Claims
- 1. A composition comprising at least two immunogenic ligands, wherein said immunogenic ligands are individually characterized by an ability to elicit an immune response against the same native ligand, and wherein said immunogenic ligand is selected from the group consisting of FLQLLMEPV (SEQ ID NO:3), FLQLEFDAV (SEQ ID NO:5), FLWFEIDIV (SEQ ID NO:7), FLSYDLFVV (SEQ ID NO:9), and NLQLLMDRV (SEQ ID NO:11).
- 2. The composition of claim 1, further comprising a carrier.
- 3. The composition of claim 2, wherein the carrier is a pharmaceutically acceptable carrier.
- 4. A host cell comprising at least two immunogenic ligands, wherein said immunogenic ligands are individually characterized by an ability to elicit an immune response against the same native ligand, and wherein said immunogenic ligand is selected from the group consisting of consisting of FLQLLMEPV (SEQ ID NO:3), FLQLEFDAV (SEQ ID NO:5), FLWFEIDIV (SEQ ID NO:7), FLSYDLFVV (SEQ ID NO:9), and NLQLLMDRV (SEQ ID NO:11).
- 5. The host cell of claim 4, wherein the host cell is an antigen presenting cell and the immunogenic ligands are presented on the surface of the cell.
- 6. The host cell of claim 5, wherein the antigen presenting cell is a dendritic cell.
- 7. A composition comprising the host cell of any of claims 4 to 6 and a carrier.
- 8. The composition of claim 7, wherein the carrier is a pharmaceutically acceptable carrier.
- 9. A method for inducing an immune response in a subject, comprising delivering to the subject a composition comprising an effective amount of two or more immunogenic ligands, wherein each of said immunogenic ligands is characterized by an ability to elicit an immune response against the same native ligand, and wherein said immunogenic ligand is selected from the group consisting of consisting of FLQLLMEPV (SEQ ID NO:3), FLQLEFDAV (SEQ ID NO:5), FLWFEIDIV (SEQ ID NO:7), FLSYDLFVV (SEQ ID NO:9), and NLQLLMDRV (SEQ ID NO:11).
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application claims priority under 35 U.S.C. § 119(e) to U.S. Provisional Application Serial Nos. 60/209,391; 60/226,258; and 60/257,008, filed May 31, 2000; Aug. 17, 2000, and Dec. 20, 2000, respectively. The contents of these applications are hereby incorporated by reference into the present disclosure.
Provisional Applications (3)
|
Number |
Date |
Country |
|
60209391 |
May 2000 |
US |
|
60226258 |
Aug 2000 |
US |
|
60257008 |
Dec 2000 |
US |