Claims
- 1. A compound of the following formula: in which X is chlorambucil and is linked to Y via the carboxyl group Y is an optional spacer group AA is an amino acid; n is a number from 0 to 5 B is H or CH2O—R3 R1, R2 and R3 are the same or different and are either hydrogen, methyl, ethyl or an acyl group derived from a fatty acid, with the proviso that at least one of R1, R2 and R3 is an acyl group derived from a fatty acid.
- 2. A compound as claimed in claim 1 in which X is chlorambucil, Y is absent, an amino acid, glycolic acid, 3-hydroxypropionic acid or lactic acid, AA is not present or glycine or alanine and the linkage is either an amide bond or an ester bond to the carboxyl group.
Priority Claims (7)
Number |
Date |
Country |
Kind |
PN0580 |
Jan 1995 |
AU |
|
PN0581 |
Jan 1995 |
AU |
|
PN0582 |
Jan 1995 |
AU |
|
PN0583 |
Jan 1995 |
AU |
|
PN0584 |
Jan 1995 |
AU |
|
PN0585 |
Jan 1995 |
AU |
|
PN0586 |
Jan 1995 |
AU |
|
Parent Case Info
This application is a divisional of application Ser. No. 08/875,098 filed Jul. 16, 1997, now U.S. Pat. No. 5,952,499, which is a 371 of PCT/AU96/0015 filed Jan. 15, 1996.
Non-Patent Literature Citations (1)
Entry |
Belogorodskii et al., Khim.-Farm. Zh., vol. 15(3), pp. 20-25, 1981. |