Alexander D. Mackerell

Person

Baltimore, MD, US

People

Patents Grantslast 30 patents

Information Patent Grant
Non-catalytic substrate-selective p38α-specific MAPK inhibitors wit...
- Patent number 11,911,392
- Issue date Feb 27, 2024
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-catalytic substrate-selective p38alpha-specific MAPK inhibitors...
- Patent number 11,911,393
- Issue date Feb 27, 2024
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors
- Patent number 11,718,595
- Issue date Aug 8, 2023
- University of Maryland, Baltimore
- Paul S. Shapiro
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
RUNX2 transcription factor inhibitors and uses thereof
- Patent number 11,634,381
- Issue date Apr 25, 2023
- University of Maryland, Baltimore
- Antonino Passaniti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Protein translation inhibitors and uses thereof
- Patent number 11,510,908
- Issue date Nov 29, 2022
- University of Maryland, Baltimore
- France Carrier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-catalytic substrate-selective, p38α-specific MAPK inhibitors wi...
- Patent number 11,357,781
- Issue date Jun 14, 2022
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-ATP/catalytic site p38 mitogen activated protein kinase inhibitors
- Patent number 11,078,171
- Issue date Aug 3, 2021
- University of Maryland, Baltimore
- Paul S. Shapiro
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Small molecule lipid II inhibitors
- Patent number 10,961,214
- Issue date Mar 30, 2021
- University of Maryland, Baltimore
- Erik de Leeuw
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Small molecule lipid II inhibitors
- Patent number 10,941,114
- Issue date Mar 9, 2021
- University of Maryland, Baltimore
- Erik de Leeuw
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of the Notch transcriptional activation complex and meth...
- Patent number 10,501,413
- Issue date Dec 10, 2019
- University of Miami
- Anthony J. Capobianco
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
RUNX2 transcription factor inhibitors and uses thereof
- Patent number 10,329,246
- Issue date Jun 25, 2019
- University of Maryland, Baltimore
- Antonino Passaniti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for binding site identification by molecular dynamics simula...
- Patent number 10,002,228
- Issue date Jun 19, 2018
- University of Maryland, Baltimore
- Alexander D. Mackerell
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Grant
BCL6 inhibitors as anticancer agents
- Patent number 9,943,506
- Issue date Apr 17, 2018
- Cornell University
- Ari Melnick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds that inhibit human DNA ligases and methods of treating ca...
- Patent number 9,757,375
- Issue date Sep 12, 2017
- University of Maryland, Baltimore
- Alan E. Tomkinson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
LRRK2 GTP binding inhibitors for treatment of Parkinson's disease a...
- Patent number 9,701,627
- Issue date Jul 11, 2017
- University of Maryland, Baltimore
- Wanli Smith
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Mixed μ agonist/ δ antagonist opioid analgesics with reduced tolera...
- Patent number 9,422,302
- Issue date Aug 23, 2016
- University of Maryland, Baltimore
- Andrew Coop
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Defensin-like molecules as novel antimicrobial agents
- Patent number 9,351,963
- Issue date May 31, 2016
- University of Maryland, Baltimore
- Erik De Leeuw
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-ATP dependent inhibitors of extracellular signal-regulated kina...
- Patent number 9,115,122
- Issue date Aug 25, 2015
- University of Maryland, Baltimore
- Paul S. Shapiro
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds that inhibit human DNA ligases and methods of treating ca...
- Patent number 9,073,896
- Issue date Jul 7, 2015
- University of Maryland, Baltimore
- Alan E. Tomkinson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Defensin-like molecules as novel antimicrobial agents
- Patent number 8,796,323
- Issue date Aug 5, 2014
- University of Maryland, Baltimore
- Erik De Leeuw
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeting NAD biosynthesis in bacterial pathogens
- Patent number 8,785,499
- Issue date Jul 22, 2014
- University of Maryland, Baltimore
- Alexander Mackerell
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
SHP-2 phosphatase inhibitor
- Patent number 8,673,913
- Issue date Mar 18, 2014
- Case Western Reserve University
- Cheng-Kui Qu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Small molecule inhibitors of Lck SH2 domain binding
- Patent number 8,476,273
- Issue date Jul 2, 2013
- University of Maryland, Baltimore
- Jun Hayashi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds that inhibit human DNA ligases and methods of treating ca...
- Patent number 8,445,537
- Issue date May 21, 2013
- STC.UNM
- Alan E. Tomkinson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of the S100-p53 protein-protein interaction and method o...
- Patent number 8,053,477
- Issue date Nov 8, 2011
- University of Maryland, Baltimore
- David J. Weber
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Immunomodulatory compounds
- Patent number 7,521,463
- Issue date Apr 21, 2009
- University of Maryland, Baltimore
- Jun Hayashi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...
- Publication number 20240366619
- Publication date Nov 7, 2024
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BETA-2 ADRENORECEPTOR MODULATORS AND METHODS OF USING SAME
- Publication number 20240150315
- Publication date May 9, 2024
- University of Maryland, Baltimore
- Alexander D. MacKerell
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX
- Publication number 20240132484
- Publication date Apr 25, 2024
- University of Maryland, Baltimore
- Matthew Frieman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS
- Publication number 20230312498
- Publication date Oct 5, 2023
- University of Maryland, Baltimore
- Paul S. SHAPIRO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...
- Publication number 20230201211
- Publication date Jun 29, 2023
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NON-ATP/CATALYTIC SITE P38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS
- Publication number 20230140941
- Publication date May 11, 2023
- University of Maryland, Baltimore
- Steven Fletcher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...
- Publication number 20220331329
- Publication date Oct 20, 2022
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX
- Publication number 20220259180
- Publication date Aug 18, 2022
- Matthew FRIEMAN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS
- Publication number 20210317097
- Publication date Oct 14, 2021
- University of Maryland, Baltimore
- Paul S. SHAPIRO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NON-CATALYTIC SUBSTRATE-SELECTIVE, P38ALPHA-SPECIFIC MAPK INHIBITOR...
- Publication number 20210267987
- Publication date Sep 2, 2021
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Protein Translation Inhibitors and Uses Thereof
- Publication number 20200368208
- Publication date Nov 26, 2020
- UNIVERSITY OF BALTIMORE, MARYLAND
- France Carrier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS
- Publication number 20200331874
- Publication date Oct 22, 2020
- University of Maryland, Baltimore
- Paul S. SHAPIRO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Small Molecule Lipid II Inhibitors
- Publication number 20200216394
- Publication date Jul 9, 2020
- University of Maryland, Baltimore
- Erik de Leeuw
- C07 - ORGANIC CHEMISTRY
Information Patent Application
RUNX2 Transcription Factor Inhibitors and Uses Thereof
- Publication number 20190263751
- Publication date Aug 29, 2019
- University of Maryland, Baltimore
- Antonino Passaniti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NON-CATALYTIC SUBSTRATE-SELECTIVE P38alpha-SPECIFIC MAPK INHIBITORS...
- Publication number 20190151324
- Publication date May 23, 2019
- University of Maryland, Baltimore
- Paul S. Shapiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Small Molecule Lipid II Inhibitors
- Publication number 20190002426
- Publication date Jan 3, 2019
- Erik de Leeuw
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND SYSTEMS FOR ORGANIC SOLUTE SAMPLING OF AQUEOUS AND HETE...
- Publication number 20180373846
- Publication date Dec 27, 2018
- University of Maryland, Baltimore
- Alexander D. MACKERELL
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
METHOD FOR BINDING SITE IDENTIFICATION BY MOLECULAR DYNAMICS SIMULA...
- Publication number 20180300447
- Publication date Oct 18, 2018
- University of Maryland, Baltimore
- Alexander D. MACKERELL
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
SMALL MOLECULE INHIBITORS OF TLR2 SIGNALING
- Publication number 20180110746
- Publication date Apr 26, 2018
- University of Maryland, Baltimore
- Stefanie N. Vogel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METH...
- Publication number 20180086700
- Publication date Mar 29, 2018
- University of Miami
- Anthony J. Capobianco
- C07 - ORGANIC CHEMISTRY
Information Patent Application
RUNX2 Transcription Factor Inhibitors and Uses Thereof
- Publication number 20180086696
- Publication date Mar 29, 2018
- University of Maryland, Baltimore
- Antonino Passaniti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND SYSTEMS FOR ORGANIC SOLUTE SAMPLING OF AQUEOUS AND HETE...
- Publication number 20160357945
- Publication date Dec 8, 2016
- University of Maryland, Baltimore
- Alexander D. MACKERELL
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
SITE-SPECIFIC FRAGMENT IDENTIFICATION GUIDED BY SINGLE-STEP FREE EN...
- Publication number 20160267219
- Publication date Sep 15, 2016
- University of Maryland, Baltimore
- Alexander D. Mackerell
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
BCL6 INHIBITORS AS ANTICANCER AGENTS
- Publication number 20160166549
- Publication date Jun 16, 2016
- Cornell University
- Ari Melnick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD FOR BINDING SITE IDENTIFICATION BY MOLECULAR DYNAMICS SIMULA...
- Publication number 20160070850
- Publication date Mar 10, 2016
- University of Maryland, Baltimore
- Alexander D. MACKERELL
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
NOVEL MIXED μ AGONIST/ δ ANTAGONIST OPIOID ANALGESICS WITH REDUCED...
- Publication number 20160016965
- Publication date Jan 21, 2016
- University of Maryland, Baltimore
- Andrew Coop
- C07 - ORGANIC CHEMISTRY
Information Patent Application
LRRK2 GTP BINDING INHIBITORS FOR TREATMENT OF PARKINSON'S DISEASE A...
- Publication number 20150361038
- Publication date Dec 17, 2015
- University of Maryland, Baltimore
- Wanli Smith
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CA...
- Publication number 20150313898
- Publication date Nov 5, 2015
- University of Maryland, Baltimore
- Alan E. Tomkinson
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
SITE-SPECIFIC FRAGMENT IDENTIFICATION GUIDED BY SINGLE-STEP FREE EN...
- Publication number 20150095007
- Publication date Apr 2, 2015
- University of Maryland, Baltimore
- Alexander D. Mackerell
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
NON-ATP DEPENDENT INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINA...
- Publication number 20140179743
- Publication date Jun 26, 2014
- University of Maryland, Baltimore
- Paul S. Shapiro
- C07 - ORGANIC CHEMISTRY

Alexander D. Mackerell

Person

Patents Grantslast 30 patents

Non-catalytic substrate-selective p38α-specific MAPK inhibitors wit...

Non-catalytic substrate-selective p38alpha-specific MAPK inhibitors...

Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors

RUNX2 transcription factor inhibitors and uses thereof

Protein translation inhibitors and uses thereof

Non-catalytic substrate-selective, p38α-specific MAPK inhibitors wi...

Non-ATP/catalytic site p38 mitogen activated protein kinase inhibitors

Small molecule lipid II inhibitors

Small molecule lipid II inhibitors

Inhibitors of the Notch transcriptional activation complex and meth...

RUNX2 transcription factor inhibitors and uses thereof

Method for binding site identification by molecular dynamics simula...

BCL6 inhibitors as anticancer agents

Compounds that inhibit human DNA ligases and methods of treating ca...

LRRK2 GTP binding inhibitors for treatment of Parkinson's disease a...

Mixed μ agonist/ δ antagonist opioid analgesics with reduced tolera...

Defensin-like molecules as novel antimicrobial agents

Non-ATP dependent inhibitors of extracellular signal-regulated kina...

Compounds that inhibit human DNA ligases and methods of treating ca...

Defensin-like molecules as novel antimicrobial agents

Targeting NAD biosynthesis in bacterial pathogens

SHP-2 phosphatase inhibitor

Small molecule inhibitors of Lck SH2 domain binding

Compounds that inhibit human DNA ligases and methods of treating ca...

Inhibitors of the S100-p53 protein-protein interaction and method o...

Immunomodulatory compounds

Patents Applicationslast 30 patents

NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...

BETA-2 ADRENORECEPTOR MODULATORS AND METHODS OF USING SAME

BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX

NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS

NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...

NON-ATP/CATALYTIC SITE P38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS

NON-CATALYTIC SUBSTRATE-SELECTIVE p38alpha-SPECIFIC MAPK INHIBITORS...

BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX

NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS

NON-CATALYTIC SUBSTRATE-SELECTIVE, P38ALPHA-SPECIFIC MAPK INHIBITOR...

Protein Translation Inhibitors and Uses Thereof

NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS

Small Molecule Lipid II Inhibitors

RUNX2 Transcription Factor Inhibitors and Uses Thereof

NON-CATALYTIC SUBSTRATE-SELECTIVE P38alpha-SPECIFIC MAPK INHIBITORS...

Small Molecule Lipid II Inhibitors

METHODS AND SYSTEMS FOR ORGANIC SOLUTE SAMPLING OF AQUEOUS AND HETE...

METHOD FOR BINDING SITE IDENTIFICATION BY MOLECULAR DYNAMICS SIMULA...

SMALL MOLECULE INHIBITORS OF TLR2 SIGNALING

INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METH...

RUNX2 Transcription Factor Inhibitors and Uses Thereof

METHODS AND SYSTEMS FOR ORGANIC SOLUTE SAMPLING OF AQUEOUS AND HETE...

SITE-SPECIFIC FRAGMENT IDENTIFICATION GUIDED BY SINGLE-STEP FREE EN...

BCL6 INHIBITORS AS ANTICANCER AGENTS

METHOD FOR BINDING SITE IDENTIFICATION BY MOLECULAR DYNAMICS SIMULA...

NOVEL MIXED μ AGONIST/ δ ANTAGONIST OPIOID ANALGESICS WITH REDUCED...

LRRK2 GTP BINDING INHIBITORS FOR TREATMENT OF PARKINSON'S DISEASE A...

COMPOUNDS THAT INHIBIT HUMAN DNA LIGASES AND METHODS OF TREATING CA...

SITE-SPECIFIC FRAGMENT IDENTIFICATION GUIDED BY SINGLE-STEP FREE EN...

NON-ATP DEPENDENT INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINA...