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Anastasia Khvorova

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  • Boulder, CO, US
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Patents Grantslast 30 patents

  • Information Patent Grant

    Branched lipid conjugates of siRNA for specific tissue delivery
    • Patent number 12,365,894
    • Issue date Jul 22, 2025
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Dual-acting siRNA based modulation of C9orf72
    • Patent number 12,344,839
    • Issue date Jul 1, 2025
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Dual-acting siRNA based modulation of C9orf72
    • Patent number 12,297,429
    • Issue date May 13, 2025
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    O-methyl rich fully stabilized oligonucleotides
    • Patent number 12,297,430
    • Issue date May 13, 2025
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Oligonucleotides for PRNP modulation
    • Patent number 12,258,566
    • Issue date Mar 25, 2025
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Dynamic pharmacokinetic-modifying anchors
    • Patent number 12,180,477
    • Issue date Dec 31, 2024
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Fully stabilized asymmetric siRNA
    • Patent number 12,173,286
    • Issue date Dec 24, 2024
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Synthesis of modified oligonucleotides with increased stability
    • Patent number 12,146,136
    • Issue date Nov 19, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Bioactive conjugates for oligonucleotide delivery
    • Patent number 12,077,755
    • Issue date Sep 3, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Grant

    Oligonucleotides for SARS-CoV-2 modulation
    • Patent number 12,077,758
    • Issue date Sep 3, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Two-tailed self-delivering siRNA
    • Patent number 12,049,627
    • Issue date Jul 30, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Oligonucleotides for tissue specific gene expression modulation
    • Patent number 12,037,585
    • Issue date Jul 16, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified oligonucleotides targeting SNPs
    • Patent number 12,024,706
    • Issue date Jul 2, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Artificial exosome composition and related methods
    • Patent number 12,023,407
    • Issue date Jul 2, 2024
    • University of Massachusetts
    • Reka Agnes Haraszti
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Branched oligonucleotides
    • Patent number 11,896,669
    • Issue date Feb 13, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified oligonucleotides targeting SNPs
    • Patent number 11,827,882
    • Issue date Nov 28, 2023
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified oligonucleotides with increased stability
    • Patent number 11,820,985
    • Issue date Nov 21, 2023
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified oligonucleotides targeting SNPs
    • Patent number 11,767,527
    • Issue date Sep 26, 2023
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Conjugated oligonucleotides
    • Patent number 11,753,638
    • Issue date Sep 12, 2023
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Optimized anti-FLT1 oligonucleotide compounds for treatment of pree...
    • Patent number 11,702,659
    • Issue date Jul 18, 2023
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    RNA duplexes with single stranded phosphorothioate nucleotide regio...
    • Patent number 11,667,915
    • Issue date Jun 6, 2023
    • Phio Pharmaceuticals Corp.
    • Tod M. Woolf
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    RNA interference in ocular indications
    • Patent number 11,584,933
    • Issue date Feb 21, 2023
    • Phio Pharmaceuticals Corp.
    • Lyn Libertine
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Exosomal loading using hydrophobically modified oligonucleotides
    • Patent number 11,505,807
    • Issue date Nov 22, 2022
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Dynamic pharmacokinetic-modifying anchors
    • Patent number 11,492,619
    • Issue date Nov 8, 2022
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Neutral nanotransporters
    • Patent number 11,396,654
    • Issue date Jul 26, 2022
    • Phio Pharmaceuticals Corp.
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Oligonucleotide compounds for treatment of preeclampsia and other a...
    • Patent number 11,345,917
    • Issue date May 31, 2022
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Grant

    O-methyl rich fully stabilized oligonucleotides
    • Patent number 11,279,930
    • Issue date Mar 22, 2022
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Inhibition of MAP4K4 through RNAi
    • Patent number 11,254,940
    • Issue date Feb 22, 2022
    • Phio Pharmaceuticals Corp.
    • Tod M. Woolf
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Oligonucleotide compounds for targeting huntingtin mRNA
    • Patent number 11,230,713
    • Issue date Jan 25, 2022
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Methods and compositions for selecting siRNA of improved functionality
    • Patent number 11,198,870
    • Issue date Dec 14, 2021
    • THERMO FISHER SCIENTIFIC INC.
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

  • Information Patent Application

    FULLY STABILIZED ASYMMETRIC SIRNA
    • Publication number 20250188458
    • Publication date Jun 12, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES WITH ETHYLENE GLYCOL MODIFICATION
    • Publication number 20250145992
    • Publication date May 8, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES WITH INTERNUCLEOTIDE LINKAGE MODIFICATIONS FOR KID...
    • Publication number 20250066780
    • Publication date Feb 27, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    SGLT-2 TARGETING OLIGONUCLEOTIDES
    • Publication number 20250059539
    • Publication date Feb 20, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY
    • Publication number 20250059533
    • Publication date Feb 20, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES FOR SNCA MODULATION
    • Publication number 20250043284
    • Publication date Feb 6, 2025
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES FOR DGAT2, FASN, OPN, AND NOX4 MODULATIONS
    • Publication number 20250034575
    • Publication date Jan 30, 2025
    • University of Massachusetts
    • Michael Czech
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES FOR SARS-CoV-2 MODULATION
    • Publication number 20240425860
    • Publication date Dec 26, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES FOR TISSUE SPECIFIC GENE EXPRESSION MODULATION
    • Publication number 20240417723
    • Publication date Dec 19, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    TUMOR DELIVERY OF DENDRITIC OLIGONUCLEOTIDES
    • Publication number 20240401042
    • Publication date Dec 5, 2024
    • University of Massachusetts
    • Hassan H. Fakih
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    DENDRITIC CONJUGATES FOR THE LUNG DELIVERY OF THERAPEUTIC OLIGONUCL...
    • Publication number 20240366773
    • Publication date Nov 7, 2024
    • University of Massachusetts
    • Hassan H. Fakih
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    DENDRITIC CONJUGATES FOR THE BRAIN DELIVERY OF THERAPEUTIC OLIGONUC...
    • Publication number 20240360444
    • Publication date Oct 31, 2024
    • University of Massachusetts
    • Hassan H. Fakih
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    DENDRITIC CONJUGATES FOR THE SKIN DELIVERY OF THERAPEUTIC OLIGONUCL...
    • Publication number 20240350526
    • Publication date Oct 24, 2024
    • University of Massachusetts
    • Hassan H. Fakih
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    COMPOSITIONS AND METHODS FOR SIRNA TREATMENT OF MUSCULAR DYSTROPHY
    • Publication number 20240352459
    • Publication date Oct 24, 2024
    • University of Massachusetts
    • Charles P. EMERSON
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY
    • Publication number 20240336916
    • Publication date Oct 10, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MODIFIED OLIGONUCLEOTIDES TARGETING SNPs
    • Publication number 20240327836
    • Publication date Oct 3, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    TOPICAL DELIVERY OF THERAPEUTIC OLIGONUCLEOTIDES
    • Publication number 20240325546
    • Publication date Oct 3, 2024
    • University of Massachusetts
    • Hassan H. Fakih
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    STABILIZATION OF OLIGONUCLEOTIDE AND OLIGONUCLEOTIDE-PROTEIN COMPLE...
    • Publication number 20240309372
    • Publication date Sep 19, 2024
    • University of Massachusetts
    • Ken Yamada
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDES FOR HTT-1A MODULATION
    • Publication number 20240301410
    • Publication date Sep 12, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CARBOHYDRATE CONJUGATES FOR THE DELIVERY OF THERAPEUTIC OLIGONUCLEO...
    • Publication number 20240293555
    • Publication date Sep 5, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    BRANCHED OLIGONUCLEOTIDES
    • Publication number 20240293550
    • Publication date Sep 5, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    OLIGONUCLEOTIDES FOR IFN-GAMMA SIGNALING PATHWAY MODULATION
    • Publication number 20240287514
    • Publication date Aug 29, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    OLIGONUCLEOTIDES TARGETING S6K1
    • Publication number 20240182904
    • Publication date Jun 6, 2024
    • University of Massachusetts
    • Claudio Punzo
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OCULAR DELIVERY OF OLIGONUCLEOTIDES
    • Publication number 20240173420
    • Publication date May 30, 2024
    • University of Massachusetts
    • Claudio Punzo
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    MODIFIED GUIDE RNAS FOR CRISPR GENOME EDITING
    • Publication number 20240167029
    • Publication date May 23, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY
    • Publication number 20240141362
    • Publication date May 2, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MODIFIED OLIGONUCLEOTIDES TARGETING SNPs
    • Publication number 20240132888
    • Publication date Apr 25, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OLIGONUCLEOTIDE-BASED MODULATION OF C9orf72
    • Publication number 20240132892
    • Publication date Apr 25, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CONJUGATED OLIGONUCLEOTIDES
    • Publication number 20240084297
    • Publication date Mar 14, 2024
    • University of Massachusetts
    • Anastasia KHVOROVA
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    OPTIMIZED ANTI-FLT1 OLIGONUCLEOTIDE COMPOUNDS FOR TREATMENT OF PREE...
    • Publication number 20240067967
    • Publication date Feb 29, 2024
    • University of Massachusetts
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...