Benjamin Kleinstiver

Person

Medford, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Unconstrained genome targeting with near-PAMless engineered CRISPR-...
- Patent number 12,312,613
- Issue date May 27, 2025
- The General Hospital Corporation
- Benjamin Kleinstiver
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
- Patent number 12,286,641
- Issue date Apr 29, 2025
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CRISPR-Cas enzymes with enhanced on-target activity
- Patent number 12,264,341
- Issue date Apr 1, 2025
- The General Hospital Corporation
- Benjamin Kleinstiver
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 12,241,096
- Issue date Mar 4, 2025
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
- Patent number 12,202,861
- Issue date Jan 21, 2025
- The General Hospital Corporation
- Y. Esther Tak
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 12,180,520
- Issue date Dec 31, 2024
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
- Patent number 12,173,339
- Issue date Dec 24, 2024
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 11,859,220
- Issue date Jan 2, 2024
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
- Patent number 11,667,677
- Issue date Jun 6, 2023
- The General Hospital Corporation
- Y. Esther Tak
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 11,624,058
- Issue date Apr 11, 2023
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
- Patent number 11,591,589
- Issue date Feb 28, 2023
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 11,286,468
- Issue date Mar 29, 2022
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 11,220,678
- Issue date Jan 11, 2022
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
- Patent number 11,168,313
- Issue date Nov 9, 2021
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 11,060,078
- Issue date Jul 13, 2021
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
- Patent number 11,021,718
- Issue date Jun 1, 2021
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 10,808,233
- Issue date Oct 20, 2020
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 10,767,168
- Issue date Sep 8, 2020
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 10,633,642
- Issue date Apr 28, 2020
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 10,526,591
- Issue date Jan 7, 2020
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 10,479,982
- Issue date Nov 19, 2019
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 10,202,589
- Issue date Feb 12, 2019
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 10,093,910
- Issue date Oct 9, 2018
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
- Patent number 9,944,912
- Issue date Apr 17, 2018
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered CRISPR-CAS9 nucleases with altered PAM specificity
- Patent number 9,926,545
- Issue date Mar 27, 2018
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 9,926,546
- Issue date Mar 27, 2018
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-CAS9 nucleases with altered PAM specificity
- Patent number 9,752,132
- Issue date Sep 5, 2017
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered CRISPR-Cas9 nucleases
- Patent number 9,512,446
- Issue date Dec 6, 2016
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20240150741
- Publication date May 9, 2024
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...
- Publication number 20230416310
- Publication date Dec 28, 2023
- The General Hospital Corporation
- Y. Esther Tak
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
- Publication number 20230407277
- Publication date Dec 21, 2023
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO CHARACTERIZE ENZYMES FOR GENOME ENGINEERING
- Publication number 20230066152
- Publication date Mar 2, 2023
- The General Hospital Corporation
- Benjamin Kleinstiver
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20230021303
- Publication date Jan 19, 2023
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
- Publication number 20220169998
- Publication date Jun 2, 2022
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20220145275
- Publication date May 12, 2022
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
- Publication number 20220025347
- Publication date Jan 27, 2022
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
- Publication number 20220017883
- Publication date Jan 20, 2022
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Engineered CRISPR-Cas9 Nucleases
- Publication number 20210355465
- Publication date Nov 18, 2021
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...
- Publication number 20210309701
- Publication date Oct 7, 2021
- The General Hospital Corporation
- Yu Gyoung Tak
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
- Publication number 20210292795
- Publication date Sep 23, 2021
- The General Hospital Corporation
- J. Keith JOUNG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-...
- Publication number 20210284978
- Publication date Sep 16, 2021
- The General Hospital Corporation
- Benjamin Kleinstiver
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Variants of CPF1 (CAS12a) With Altered PAM Specificity
- Publication number 20210269788
- Publication date Sep 2, 2021
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CRISPR-CAS ENZYMES WITH ENHANCED ON-TARGET ACTIVITY
- Publication number 20210261932
- Publication date Aug 26, 2021
- The General Hospital Corporation
- Benjamin Kleinstiver
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20200399620
- Publication date Dec 24, 2020
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20200399621
- Publication date Dec 24, 2020
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20200149023
- Publication date May 14, 2020
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 Nucleases
- Publication number 20200149024
- Publication date May 14, 2020
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 Nucleases
- Publication number 20200140835
- Publication date May 7, 2020
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
- Publication number 20190106687
- Publication date Apr 11, 2019
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 Nucleases
- Publication number 20190071657
- Publication date Mar 7, 2019
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Variants of CPF1 (CAS12a) With Altered PAM Specificity
- Publication number 20190010481
- Publication date Jan 10, 2019
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
- Publication number 20180282714
- Publication date Oct 4, 2018
- The General Hospital Corporation
- J. Keith Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
- Publication number 20180230494
- Publication date Aug 16, 2018
- The General Hospital Corporation
- J. Keith JOUNG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Engineered CRISPR-Cas9 Nucleases
- Publication number 20180216088
- Publication date Aug 2, 2018
- The General Hospital Corporation
- J. Keith Joung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
- Publication number 20180030425
- Publication date Feb 1, 2018
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20180002681
- Publication date Jan 4, 2018
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20170327806
- Publication date Nov 16, 2017
- The General Hospital Corporation
- J. Keith Joung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
- Publication number 20170327804
- Publication date Nov 16, 2017
- The General Hospital Corporation
- J. Keith Joung
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING

Benjamin Kleinstiver

Person

Patents Grantslast 30 patents

Unconstrained genome targeting with near-PAMless engineered CRISPR-...

Methods for increasing efficiency of nuclease-induced homology-dire...

CRISPR-Cas enzymes with enhanced on-target activity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Inducible, tunable, and multiplex human gene regulation using CRISP...

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Variants of Cpf1 (Cas12a) with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Inducible, tunable, and multiplex human gene regulation using CRISP...

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Variants of Cpf1 (Cas12a) with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)

Engineered CRISPR-Cas9 nucleases

Methods for increasing efficiency of nuclease-induced homology-dire...

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-CAS9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-CAS9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases

Patents Applicationslast 30 patents

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...

Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity

METHODS TO CHARACTERIZE ENZYMES FOR GENOME ENGINEERING

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)

Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)

Engineered CRISPR-Cas9 Nucleases

Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...

METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...

Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-...

Variants of CPF1 (CAS12a) With Altered PAM Specificity

CRISPR-CAS ENZYMES WITH ENHANCED ON-TARGET ACTIVITY

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 Nucleases

Engineered CRISPR-Cas9 Nucleases

Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 Nucleases

Variants of CPF1 (CAS12a) With Altered PAM Specificity

Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity

METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...

Engineered CRISPR-Cas9 Nucleases

Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity

Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity