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Benjamin Kleinstiver
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Medford, MA, US
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Patents Grants
last 30 patents
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Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
Patent number
12,202,861
Issue date
Jan 21, 2025
The General Hospital Corporation
Y. Esther Tak
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
12,180,520
Issue date
Dec 31, 2024
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
Patent number
12,173,339
Issue date
Dec 24, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,859,220
Issue date
Jan 2, 2024
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
Patent number
11,667,677
Issue date
Jun 6, 2023
The General Hospital Corporation
Y. Esther Tak
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,624,058
Issue date
Apr 11, 2023
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
Patent number
11,591,589
Issue date
Feb 28, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,286,468
Issue date
Mar 29, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,220,678
Issue date
Jan 11, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Patent number
11,168,313
Issue date
Nov 9, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
11,060,078
Issue date
Jul 13, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
Patent number
11,021,718
Issue date
Jun 1, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
10,808,233
Issue date
Oct 20, 2020
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
10,767,168
Issue date
Sep 8, 2020
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
10,633,642
Issue date
Apr 28, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
10,526,591
Issue date
Jan 7, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
10,479,982
Issue date
Nov 19, 2019
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
10,202,589
Issue date
Feb 12, 2019
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
10,093,910
Issue date
Oct 9, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
9,944,912
Issue date
Apr 17, 2018
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered CRISPR-CAS9 nucleases with altered PAM specificity
Patent number
9,926,545
Issue date
Mar 27, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
9,926,546
Issue date
Mar 27, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-CAS9 nucleases with altered PAM specificity
Patent number
9,752,132
Issue date
Sep 5, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
9,512,446
Issue date
Dec 6, 2016
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20240150741
Publication date
May 9, 2024
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...
Publication number
20230416310
Publication date
Dec 28, 2023
The General Hospital Corporation
Y. Esther Tak
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20230407277
Publication date
Dec 21, 2023
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS TO CHARACTERIZE ENZYMES FOR GENOME ENGINEERING
Publication number
20230066152
Publication date
Mar 2, 2023
The General Hospital Corporation
Benjamin Kleinstiver
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20230021303
Publication date
Jan 19, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20220169998
Publication date
Jun 2, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20220145275
Publication date
May 12, 2022
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Publication number
20220025347
Publication date
Jan 27, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Publication number
20220017883
Publication date
Jan 20, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases
Publication number
20210355465
Publication date
Nov 18, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...
Publication number
20210309701
Publication date
Oct 7, 2021
The General Hospital Corporation
Yu Gyoung Tak
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
Publication number
20210292795
Publication date
Sep 23, 2021
The General Hospital Corporation
J. Keith JOUNG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Unconstrained Genome Targeting with near-PAMless Engineered CRISPR-...
Publication number
20210284978
Publication date
Sep 16, 2021
The General Hospital Corporation
Benjamin Kleinstiver
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Variants of CPF1 (CAS12a) With Altered PAM Specificity
Publication number
20210269788
Publication date
Sep 2, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS ENZYMES WITH ENHANCED ON-TARGET ACTIVITY
Publication number
20210261932
Publication date
Aug 26, 2021
The General Hospital Corporation
Benjamin Kleinstiver
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20200399620
Publication date
Dec 24, 2020
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20200399621
Publication date
Dec 24, 2020
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20200149023
Publication date
May 14, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases
Publication number
20200149024
Publication date
May 14, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases
Publication number
20200140835
Publication date
May 7, 2020
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20190106687
Publication date
Apr 11, 2019
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases
Publication number
20190071657
Publication date
Mar 7, 2019
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Variants of CPF1 (CAS12a) With Altered PAM Specificity
Publication number
20190010481
Publication date
Jan 10, 2019
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20180282714
Publication date
Oct 4, 2018
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
Publication number
20180230494
Publication date
Aug 16, 2018
The General Hospital Corporation
J. Keith JOUNG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases
Publication number
20180216088
Publication date
Aug 2, 2018
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Publication number
20180030425
Publication date
Feb 1, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20180002681
Publication date
Jan 4, 2018
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20170327806
Publication date
Nov 16, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20170327804
Publication date
Nov 16, 2017
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING