Darell Bigner

Person

Mebane, NC, US

People

Patents Grantslast 30 patents

Information Patent Grant
Oncolytic poliovirus for human tumors
- Patent number 11,813,298
- Issue date Nov 14, 2023
- Duke University
- Matthias Gromeier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Detection of CD-155, the poliovirus receptor
- Patent number 11,506,666
- Issue date Nov 22, 2022
- Duke University
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods for predicting tumor response to immunotherapy
- Patent number 11,428,691
- Issue date Aug 30, 2022
- Duke University
- David Ashley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oncolytic poliovirus for human tumors
- Patent number 11,406,677
- Issue date Aug 9, 2022
- Duke University
- Matthias Gromeier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for activating antigen presenting cells wi...
- Patent number 11,331,343
- Issue date May 17, 2022
- Duke University
- Smita Nair
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Production of immunotoxin D2C7—(scdsFv)—PE38KDEL
- Patent number 11,311,628
- Issue date Apr 26, 2022
- Duke University
- Darell D. Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
TERT promoter mutations in gliomas and a subset of tumors
- Patent number 11,306,364
- Issue date Apr 19, 2022
- Duke University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Somatic mutations in ATRX in brain cancer
- Patent number 11,254,988
- Issue date Feb 22, 2022
- The Johns Hopkins University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Combination therapy of immunotoxin and checkpoint inhibitor
- Patent number 11,065,332
- Issue date Jul 20, 2021
- Duke University
- Darell Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Genetic alterations in isocitrate dehydrogenase and other genes in...
- Patent number 10,894,987
- Issue date Jan 19, 2021
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetic alterations in isocitrate dehydrogenase and other genes in...
- Patent number 10,837,064
- Issue date Nov 17, 2020
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oncolytic poliovirus for human tumors
- Patent number 10,799,543
- Issue date Oct 13, 2020
- Duke University
- Matthias Gromeier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Combination treatment
- Patent number 10,744,170
- Issue date Aug 18, 2020
- Duke University
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sequential anti-cancer treatment
- Patent number 10,744,171
- Issue date Aug 18, 2020
- Duke University
- Darell D. Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Tert promoter mutations in gliomas and a subset of tumors
- Patent number 10,711,310
- Issue date Jul 14, 2020
- Duke University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetic alterations in isocitrate dehydrogenase and other genes in...
- Patent number 10,704,108
- Issue date Jul 7, 2020
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for rapid and sensitive detection of hotspot mutations
- Patent number 10,633,711
- Issue date Apr 28, 2020
- Duke University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligodendroglioma drive genes
- Patent number 10,619,217
- Issue date Apr 14, 2020
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oncolytic poliovirus for human tumors
- Patent number 10,398,743
- Issue date Sep 3, 2019
- Duke University
- Matthias Gromeier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Dual specific immunotoxin for brain tumor therapy
- Patent number 10,072,084
- Issue date Sep 11, 2018
- Duke University
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Human bispecific EGFRvIII and CD3 antibody engaging molecules
- Patent number 10,053,514
- Issue date Aug 21, 2018
- Duke University
- Darell D. Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for using antibodies for 3′ iso-LM1 and 3′, 6′-iso-LD1tumor...
- Patent number 10,052,382
- Issue date Aug 21, 2018
- Duke University
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Somatic mutations in ATRX in brain cancer
- Patent number 9,982,306
- Issue date May 29, 2018
- Duke University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligodendroglioma drive genes
- Patent number 9,873,917
- Issue date Jan 23, 2018
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Medulloblastoma genes as targets for diagnosis and therapeutics
- Patent number 9,695,479
- Issue date Jul 4, 2017
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Homozygous and heterozygous IDH1 gene-defective human astrocytoma c...
- Patent number 9,695,400
- Issue date Jul 4, 2017
- Duke University
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human bispecific EGFRvIII antibody and CD3 engaging molecules
- Patent number 9,676,858
- Issue date Jun 13, 2017
- Duke University
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Dual specific immunotoxin for brain tumor therapy
- Patent number 9,492,564
- Issue date Nov 15, 2016
- Duke University
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody for 3′-isoLM1 and 3′,6′-iso-LD1 gangliosides
- Patent number 9,441,048
- Issue date Sep 13, 2016
- The United States of America as represented by the Secretary of Health & Huma...
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Concurrent chemotherapy and immunotherapy
- Patent number 9,399,662
- Issue date Jul 26, 2016
- Duke University
- John H. Sampson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
Combination Treatment
- Publication number 20240415906
- Publication date Dec 19, 2024
- DUKE UNIVERSITY
- Darell D. Bigner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...
- Publication number 20240392381
- Publication date Nov 28, 2024
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Combination Therapy of Immunotoxin and Checkpoint Inhibitor
- Publication number 20240350624
- Publication date Oct 24, 2024
- DUKE UNIVERSITY
- Darell Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
D2C7 EGFR AND EGFR VIII BI-SPECIFIC CHIMERIC ANTIGEN RECEPTOR CONST...
- Publication number 20240293546
- Publication date Sep 5, 2024
- DUKE UNIVERSITY
- Peter FECCI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IMMUNOTHERAPY WITH COMBINATION THERAPY COMPRISING AN IMMUNOTOXIN
- Publication number 20230141413
- Publication date May 11, 2023
- DUKE UNIVERSITY
- Darell BIGNER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TREATMENT FOR PRIMARY AND METASTATIC CANCER
- Publication number 20220387529
- Publication date Dec 8, 2022
- DUKE UNIVERSITY
- Darell BIGNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Oncolytic Poliovirus for Human Tumors
- Publication number 20220339223
- Publication date Oct 27, 2022
- DUKE UNIVERSITY
- Matthias Gromeier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Combination Therapy of Immunotoxin and Checkpoint Inhibitor
- Publication number 20210338811
- Publication date Nov 4, 2021
- DUKE UNIVERSITY
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...
- Publication number 20210317532
- Publication date Oct 14, 2021
- The Johns Hopkins University
- Bert VOGELSTEIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DETECTION OF CD-155, THE POLIOVIRUS RECEPTOR
- Publication number 20210311063
- Publication date Oct 7, 2021
- DUKE UNIVERSITY
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NEOADJUVANT CANCER TREATMENT WITH IMMUNOTOXIN AND CHECKPOINT INHIBI...
- Publication number 20210214442
- Publication date Jul 15, 2021
- DUKE UNIVERSITY
- Darell BIGNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NEOADJUVANT CANCER TREATMENT
- Publication number 20210106633
- Publication date Apr 15, 2021
- DUKE UNIVERSITY
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Methods For Predicting Tumor Response To Immunotherapy
- Publication number 20210063398
- Publication date Mar 4, 2021
- DUKE UNIVERSITY
- David Ashley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Oncolytic Poliovirus for Human Tumors
- Publication number 20200405795
- Publication date Dec 31, 2020
- DUKE UNIVERSITY
- Matthias Gromeier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TERT Promoter Mutations in Gliomas and a Subset of Tumors
- Publication number 20200399708
- Publication date Dec 24, 2020
- DUKE UNIVERSITY
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Combination Treatment
- Publication number 20200368300
- Publication date Nov 26, 2020
- DUKE UNIVERSITY
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Production of Immunotoxin D2C7 - (scdsFv) -PE38KDEL
- Publication number 20200046847
- Publication date Feb 13, 2020
- DUKE UNIVERSITY
- Darell D. Bigner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Oncolytic Poliovirus for Human Tumors
- Publication number 20190343904
- Publication date Nov 14, 2019
- DUKE UNIVERSITY
- Matthias Gromeier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR ACTIVATING ANTIGEN PRESENTING CELLS WI...
- Publication number 20190167718
- Publication date Jun 6, 2019
- DUKE UNIVERSITY
- Smita Nair
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Sequential Anti-Cancer Treatment
- Publication number 20190105360
- Publication date Apr 11, 2019
- DUKE UNIVERSITY
- Darell D. Bigner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...
- Publication number 20190106752
- Publication date Apr 11, 2019
- The Johns Hopkins University
- Bert VOGELSTEIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Certain Improved Human Bispecific EGFRvIII Antibody Engaging Molecules
- Publication number 20180362659
- Publication date Dec 20, 2018
- THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF HEALTH...
- Darell D. Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SOMATIC MUTATIONS IN ATRX IN BRAIN CANCER
- Publication number 20180334726
- Publication date Nov 22, 2018
- The Johns Hopkins University
- Hai Yan
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION THERAPY OF IMMUNOTOXIN AND CHECKPOINT INHIBITOR
- Publication number 20180311346
- Publication date Nov 1, 2018
- DUKE UNIVERSITY
- Darell Bigner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Combination Treatment
- Publication number 20180296614
- Publication date Oct 18, 2018
- DUKE UNIVERSITY
- Darell D. Bigner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...
- Publication number 20180282821
- Publication date Oct 4, 2018
- The Johns Hopkins University
- Bert VOGELSTEIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Concurrent Chemotherapy and Immunotherapy
- Publication number 20180215789
- Publication date Aug 2, 2018
- DUKE UNIVERSITY
- John H. Sampson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OLIGODENDROGLIOMA DRIVE GENES
- Publication number 20180195132
- Publication date Jul 12, 2018
- The Johns Hopkins University
- Bert Vogelstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR RAPID AND SENSITIVE DETECTION OF HOTSPOT MUTATIONS
- Publication number 20170247765
- Publication date Aug 31, 2017
- DUKE UNIVERSITY
- Hai Yan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Oncolytic Poliovirus for Human Tumors
- Publication number 20170216382
- Publication date Aug 3, 2017
- DUKE UNIVERSITY
- Matthias Gromeier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Darell Bigner

Person

Patents Grantslast 30 patents

Oncolytic poliovirus for human tumors

Detection of CD-155, the poliovirus receptor

Methods for predicting tumor response to immunotherapy

Oncolytic poliovirus for human tumors

Compositions and methods for activating antigen presenting cells wi...

Production of immunotoxin D2C7—(scdsFv)—PE38KDEL

TERT promoter mutations in gliomas and a subset of tumors

Somatic mutations in ATRX in brain cancer

Combination therapy of immunotoxin and checkpoint inhibitor

Genetic alterations in isocitrate dehydrogenase and other genes in...

Genetic alterations in isocitrate dehydrogenase and other genes in...

Oncolytic poliovirus for human tumors

Combination treatment

Sequential anti-cancer treatment

Tert promoter mutations in gliomas and a subset of tumors

Genetic alterations in isocitrate dehydrogenase and other genes in...

Methods for rapid and sensitive detection of hotspot mutations

Oligodendroglioma drive genes

Oncolytic poliovirus for human tumors

Dual specific immunotoxin for brain tumor therapy

Human bispecific EGFRvIII and CD3 antibody engaging molecules

Methods for using antibodies for 3′ iso-LM1 and 3′, 6′-iso-LD1tumor...

Somatic mutations in ATRX in brain cancer

Oligodendroglioma drive genes

Medulloblastoma genes as targets for diagnosis and therapeutics

Homozygous and heterozygous IDH1 gene-defective human astrocytoma c...

Human bispecific EGFRvIII antibody and CD3 engaging molecules

Dual specific immunotoxin for brain tumor therapy

Antibody for 3′-isoLM1 and 3′,6′-iso-LD1 gangliosides

Concurrent chemotherapy and immunotherapy

Patents Applicationslast 30 patents

Combination Treatment

GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...

Combination Therapy of Immunotoxin and Checkpoint Inhibitor

D2C7 EGFR AND EGFR VIII BI-SPECIFIC CHIMERIC ANTIGEN RECEPTOR CONST...

IMMUNOTHERAPY WITH COMBINATION THERAPY COMPRISING AN IMMUNOTOXIN

TREATMENT FOR PRIMARY AND METASTATIC CANCER

Oncolytic Poliovirus for Human Tumors

Combination Therapy of Immunotoxin and Checkpoint Inhibitor

GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...

DETECTION OF CD-155, THE POLIOVIRUS RECEPTOR

NEOADJUVANT CANCER TREATMENT WITH IMMUNOTOXIN AND CHECKPOINT INHIBI...

NEOADJUVANT CANCER TREATMENT

Methods For Predicting Tumor Response To Immunotherapy

Oncolytic Poliovirus for Human Tumors

TERT Promoter Mutations in Gliomas and a Subset of Tumors

Combination Treatment

Production of Immunotoxin D2C7 - (scdsFv) -PE38KDEL

Oncolytic Poliovirus for Human Tumors

COMPOSITIONS AND METHODS FOR ACTIVATING ANTIGEN PRESENTING CELLS WI...

Sequential Anti-Cancer Treatment

GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...

Certain Improved Human Bispecific EGFRvIII Antibody Engaging Molecules

SOMATIC MUTATIONS IN ATRX IN BRAIN CANCER

COMBINATION THERAPY OF IMMUNOTOXIN AND CHECKPOINT INHIBITOR

Combination Treatment

GENETIC ALTERATIONS IN ISOCITRATE DEHYDROGENASE AND OTHER GENES IN...

Concurrent Chemotherapy and Immunotherapy

OLIGODENDROGLIOMA DRIVE GENES

METHODS FOR RAPID AND SENSITIVE DETECTION OF HOTSPOT MUTATIONS

Oncolytic Poliovirus for Human Tumors