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George N. PAVLAKIS
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Bethesda, MD, US
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Patents Grants
last 30 patents
Information
Patent Grant
Codon optimized IL-15 and IL-15R-alpha genes for expression in mamm...
Patent number
11,339,198
Issue date
May 24, 2022
THE UNITED STATES OF AMERICA, AS REPRESENTED BY, THE SECRETARY, DEPARTMENT OF...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Altering the immundominance hierarchy using a DNA vaccine expressin...
Patent number
11,167,025
Issue date
Nov 9, 2021
The United States of America, as represented by the Secretary, Department of...
George Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Complexes of IL-15 and IL-15Ralpha and uses thereof
Patent number
11,110,150
Issue date
Sep 7, 2021
Novartis AG
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterodimers of IL-15 and IL-15R alpha to increase thymic output an...
Patent number
11,041,008
Issue date
Jun 22, 2021
The Government of the United States of America as represented by the Secretar...
Cristina Bergamaschi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Use of IL-15 to increase thymic output and to treat lymphopenia
Patent number
10,894,816
Issue date
Jan 19, 2021
The Government of the United States of America as represented by the Secretar...
George N. Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Altering the immundominance hierarchy using a DNA vaccine expressin...
Patent number
10,426,830
Issue date
Oct 1, 2019
The United States of America as represented by the Secretary, Department of H...
George Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Codon optimized IL-15 and IL-15R-alpha genes for expression in mamm...
Patent number
10,428,133
Issue date
Oct 1, 2019
The United States of America, as represented by the Secretary, Department of...
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
IL-15 and IL-15Rα heterodimer dose escalation regimens for treating...
Patent number
10,335,460
Issue date
Jul 2, 2019
Novartis AG
Barbara K. Felber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Complexes of IL-15 and IL-15Ralpha and uses thereof
Patent number
10,265,382
Issue date
Apr 23, 2019
Novartis AG
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heterodimers of IL-15 and IL-15R alpha to increase thymic output an...
Patent number
10,093,710
Issue date
Oct 9, 2018
The United States of America as represented by the Secretary of the Departmen...
George N. Pavlakis
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heterodimers of IL-15 and IL-15R alpha to increase thymic output an...
Patent number
9,975,937
Issue date
May 22, 2018
THE UNITED SSTATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cell expressing complexes of IL-15 and IL-15Ralpha
Patent number
9,931,377
Issue date
Apr 3, 2018
The United States of America, as represented by the Secretary, Department of...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Codon optimized IL-15 and IL-15R-alpha genes for expression in mamm...
Patent number
9,790,261
Issue date
Oct 17, 2017
The United States of America, as represented by the Secretary, Department of...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Codon optimized IL-15 and IL-15R-alpha genes for expression in mamm...
Patent number
9,725,492
Issue date
Aug 8, 2017
The United States of America, as represented by the Secretary, Department of...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Expression of IL-12 family heterodimers
Patent number
9,546,202
Issue date
Jan 17, 2017
The United States of America, as represented by the Secretary, Department of...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method of altering the immundominance hierarchy of HIV gag by DNA v...
Patent number
9,415,099
Issue date
Aug 16, 2016
The United States of America as represented by the Secretary of the Departmen...
George Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Codon optimized IL-15 and IL-15R-alpha genes for expression in mamm...
Patent number
9,303,080
Issue date
Apr 5, 2016
The United States of America as represented by the Secretary of the Departmen...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Use of IL-15 preparations to treat lymphopenia
Patent number
8,871,191
Issue date
Oct 28, 2014
The United States of America as represented by the Secretary of the Departmen...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Expression of IL-12 family heterodimers
Patent number
8,715,964
Issue date
May 6, 2014
The United States of America as represented by the Secretary of the Departmen...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
DNA immunization protocols
Patent number
8,586,055
Issue date
Nov 19, 2013
The United States of America as represented by the Secretary of the Departmen...
Barbara Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Potent combinations of mRNA transport elements
Patent number
8,163,542
Issue date
Apr 24, 2012
The United States of America as represented by the Secretary of the Departmen...
Barbara Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
Patent number
8,076,100
Issue date
Dec 13, 2011
The United States of America as represented by the Department of Health and H...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
IL-12 for expression in mammalian cell
Patent number
7,833,754
Issue date
Nov 16, 2010
The United States of America as represented by the Secretary of the Departmen...
Barbara Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of potentiating HIV-1-specific CD8+ immune responses involv...
Patent number
7,771,729
Issue date
Aug 10, 2010
The United States of America as represented by the Department of Health and H...
Genoveffa Franchini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Simian immunodeficiency virus (SIV) molecular clone encoding mutant...
Patent number
7,608,422
Issue date
Oct 27, 2009
The United States of America as represented by the Secretary of the Departmen...
George N. Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Liposome complexes for increased systemic delivery
Patent number
7,288,266
Issue date
Oct 30, 2007
United States of America as represented by the Secretary, Department of Healt...
Nancy Smyth-Templeton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Immunogenicity using a combination of DNA and vaccinia virus vector...
Patent number
7,094,408
Issue date
Aug 22, 2006
The United States of America as represented by the Department of Health and H...
Genoveffa Franchini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Liposome complexes for increased systemic delivery
Patent number
7,001,614
Issue date
Feb 21, 2006
The United States of America as represented by the Department of Health and H...
Nancy Smyth-Templeton
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acids comprising a post-transcriptional regulatory element...
Patent number
6,919,442
Issue date
Jul 19, 2005
The United States of America as represented by the Department of Health and H...
George N. Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method of eliminating inhibitory/instability regions of mRNA
Patent number
6,794,498
Issue date
Sep 21, 2004
The United States of America as represented by the Department of Health and H...
George N. Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
IL-15R ALPHA FORMS, CELLS EXPRESSING IL-15R ALPHA FORMS, AND THERAP...
Publication number
20250108092
Publication date
Apr 3, 2025
Novartis AG
Barbara K. Felber
Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information
Patent Application
METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE USING CONS...
Publication number
20230340029
Publication date
Oct 26, 2023
The United States of America as Represented by the Secretary, Department of
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CODON OPTIMIZED IL-15 AND IL-15R-ALPHA GENES FOR EXPRESSION IN MAMM...
Publication number
20200231643
Publication date
Jul 23, 2020
THE UNITED STATED OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF...
Barbara K. FELBER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Altering the Immundominance Hierarchy Using a DNA Vaccine Expressin...
Publication number
20190381166
Publication date
Dec 19, 2019
The United States of America, as represented by the Secretary, Department of...
George Pavlakis
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPLEXES OF IL-15 AND IL-15RALPHA AND USES THEREOF
Publication number
20190290734
Publication date
Sep 26, 2019
Novartis AG
Barbara K. FELBER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IL-15R ALPHA FORMS, CELLS EXPRESSING IL-15R ALPHA FORMS, AND THERAP...
Publication number
20190209653
Publication date
Jul 11, 2019
THE GOVERNMENT, DEPT OF HEALTH AND HUMAN SERVICES
Barbara K. FELBER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
USE OF HETERODIMERIC IL-15 IN ADOPTIVE CELL TRANSFER
Publication number
20190117690
Publication date
Apr 25, 2019
THE UNIVERSITY STATE OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPAR...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETERODIMERS OF IL-15 AND IL-15R ALPHA TO INCREASE THYMIC OUTPUT AN...
Publication number
20190048056
Publication date
Feb 14, 2019
The Government of the United States of America as Represented by the Secretar...
Cristina Bergamaschi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE USING CONS...
Publication number
20180346520
Publication date
Dec 6, 2018
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTME...
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
USE OF IL-15 TO INCREASE THYMIC OUTPUT AND TO TREAT LYMPHOPENIA
Publication number
20180291075
Publication date
Oct 11, 2018
The Government of the United States of America as Represented by the Secretar...
George N. Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CODON OPTIMIZED IL-15 AND IL-15R-ALPHA GENES FOR EXPRESSION IN MAMM...
Publication number
20180044392
Publication date
Feb 15, 2018
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HETERODIMERS OF IL-15 AND IL-15R ALPHA TO INCREASE THYMIC OUTPUT AN...
Publication number
20170226174
Publication date
Aug 10, 2017
The Government of the United States of America as Represented by the Secretar...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IL-15 AND IL-15RALPHA HETERODIMER DOSE ESCALATION REGIMENS FOR TREA...
Publication number
20170202924
Publication date
Jul 20, 2017
Novartis AG
Barbara K. FELBER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPLEXES OF IL-15 AND IL-15RALPHA AND USES THEREOF
Publication number
20170151310
Publication date
Jun 1, 2017
Novartis AG
Barbara K. FELBER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Altering the Immundominance Hierarchy Using a DNA Vaccine Expressin...
Publication number
20170028056
Publication date
Feb 2, 2017
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMEN...
George Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CODON OPTIMIZED IL-15 AND IL-15R-ALPHA GENES FOR EXPRESSION IN MAMM...
Publication number
20160102128
Publication date
Apr 14, 2016
The U.S.A as Represented by the Secretary of the Department of Health and Hum...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CODON OPTIMIZED IL-15 AND IL-15R-ALPHA GENES FOR EXPRESSION IN MAMM...
Publication number
20160096875
Publication date
Apr 7, 2016
The United States of America as Represented by the Secretary of the Departmen...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Application
IL-15R ALPHA FORMS, CELLS EXPRESSING IL-15R ALPHA FORMS, AND THERAP...
Publication number
20150359853
Publication date
Dec 17, 2015
ADMUNE THERAPEUTICS LLC
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
USE OF IL-15 PREPARATIONS TO TREAT LYMPHOPENIA
Publication number
20150246956
Publication date
Sep 3, 2015
The Government of the United States of America as Represented by the Secretar...
George N. Pavlakis
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD OF ALTERING THE IMMUNDOMINANCE HIERARCHY OF HIV GAG BY DNA V...
Publication number
20150056237
Publication date
Feb 26, 2015
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETAR...
George Pavlakis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EXPRESSION OF IL-12 FAMILY HETERODIMERS
Publication number
20140206758
Publication date
Jul 24, 2014
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DNA-PROTEIN VACCINATION PROTOCOLS
Publication number
20130052221
Publication date
Feb 28, 2013
The Govt. of the U.S, as represented by The Sec. of The Dept. of Health and H...
Barbara K. Felber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
USE OF IL-15 PREPARATIONS TO TREAT LYMPHOPENIA
Publication number
20120141413
Publication date
Jun 7, 2012
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
EXPRESSION VECTORS ABLE TO ELICIT IMPROVED IMMUNE RESPONSE AND METH...
Publication number
20120027792
Publication date
Feb 2, 2012
The Gov of the USA as represented by the Secretary of the Dept. of Health & H...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IMPROVED EXPRESSION OF IL-12 FAMILY HETERODIMERS
Publication number
20110166210
Publication date
Jul 7, 2011
The Govt. of the U.S.A. as represented by the Sec. of the Dept. of Health and...
Barbara K. Felber
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPLEXES OF IL-15 AND IL-15RALPHA AND USES THEREOF
Publication number
20110081311
Publication date
Apr 7, 2011
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IMMUNOGENICITY USING A COMBINATION OF DNA AND VACCINIA VIRUS VECTOR...
Publication number
20100291037
Publication date
Nov 18, 2010
The United States of America, as Represented by the Secretary, Dept. of Healt...
Genoveffa Franchini
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DNA VACCINATION PROTOCOLS
Publication number
20100285061
Publication date
Nov 11, 2010
The Government of the United States, as represented by The Secretary of The D...
Barbara Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Expression Vectors Able to Elicit Improved Immune Response and Meth...
Publication number
20090227664
Publication date
Sep 10, 2009
The Government of the United States of America as represented by the Secretar...
George N. Pavlakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DNA-BASED VACCINATION OF RETROVIRAL-INFECTED INDIVIDUALS UNDERGOING...
Publication number
20090169503
Publication date
Jul 2, 2009
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF DEPT...
Barbara K. Felber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE