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J. Keith JOUNG
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Winchester, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Engineered human-endogenous virus-like particles and methods of use...
Patent number
12,351,814
Issue date
Jul 8, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered human-endogenous virus-like particles and methods of use...
Patent number
12,351,815
Issue date
Jul 8, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Enhanced virus-like particles and methods of use thereof for delive...
Patent number
12,319,938
Issue date
Jun 3, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
Patent number
12,286,641
Issue date
Apr 29, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
12,241,096
Issue date
Mar 4, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
Patent number
12,202,861
Issue date
Jan 21, 2025
The General Hospital Corporation
Y. Esther Tak
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
12,180,520
Issue date
Dec 31, 2024
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
Patent number
12,173,339
Issue date
Dec 24, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
TAL-Tet1 fusion proteins and methods of use thereof
Patent number
12,152,254
Issue date
Nov 26, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genomewide unbiased identification of DSBs evaluated by sequencing...
Patent number
12,104,207
Issue date
Oct 1, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-guided targeting of genetic and epigenomic regulatory proteins...
Patent number
12,065,668
Issue date
Aug 20, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Highly sensitive in vitro assays to define substrate preferences an...
Patent number
11,976,324
Issue date
May 7, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adenine DNA base editor variants with reduced off-target RNA editing
Patent number
11,946,040
Issue date
Apr 2, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Increasing specificity for RNA-guided genome editing
Patent number
11,920,152
Issue date
Mar 5, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Highly sensitive in vitro assays to define substrate preferences an...
Patent number
11,898,203
Issue date
Feb 13, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,859,220
Issue date
Jan 2, 2024
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Highly sensitive in vitro assays to define substrate preferences an...
Patent number
11,845,987
Issue date
Dec 19, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for detecting site-specific and spurious genomic deaminatio...
Patent number
11,725,228
Issue date
Aug 15, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Inducible, tunable, and multiplex human gene regulation using CRISP...
Patent number
11,667,677
Issue date
Jun 6, 2023
The General Hospital Corporation
Y. Esther Tak
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Using truncated guide RNAs (tru-gRNAs) to increase specificity for...
Patent number
11,634,731
Issue date
Apr 25, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,624,058
Issue date
Apr 11, 2023
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Variants of Cpf1 (Cas12a) with altered PAM specificity
Patent number
11,591,589
Issue date
Feb 28, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of transcription activator like effector assembly
Patent number
11,472,849
Issue date
Oct 18, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Base editors with improved precision and specificity
Patent number
11,326,157
Issue date
May 10, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,286,468
Issue date
Mar 29, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Patent number
11,220,678
Issue date
Jan 11, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Patent number
11,168,313
Issue date
Nov 9, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-guided targeting of genetic and epigenomic regulatory proteins...
Patent number
11,168,338
Issue date
Nov 9, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using RNA-guided FokI nucleases (RFNs) to increase specificity for...
Patent number
11,098,326
Issue date
Aug 24, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Engineered CRISPR-Cas9 nucleases
Patent number
11,060,078
Issue date
Jul 13, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
TAL-Tet1 Fusion Proteins and Methods of Use Thereof
Publication number
20250115884
Publication date
Apr 10, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins...
Publication number
20250034597
Publication date
Jan 30, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HIGHLY SENSITIVE IN VITRO ASSAYS TO DEFINE SUBSTRATE PREFERENCES AN...
Publication number
20240309446
Publication date
Sep 19, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Increasing Specificity for RNA-Guided Genome Editing
Publication number
20240240207
Publication date
Jul 18, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HIGHLY SENSITIVE IN VITRO ASSAYS TO DEFINE SUBSTRATE PREFERENCES AN...
Publication number
20240200130
Publication date
Jun 20, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Virus-like Particles with Programmable Tropism and Methods of Use T...
Publication number
20240191256
Publication date
Jun 13, 2024
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Minimal Virus-Like Particles and Methods of Use Thereof for Deliver...
Publication number
20240191208
Publication date
Jun 13, 2024
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Minimal Human-Derived Virus-Like Particles and Methods of Use There...
Publication number
20240189247
Publication date
Jun 13, 2024
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20240150741
Publication date
May 9, 2024
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for Detecting Site-Specific and Spurious Genomic Deaminatio...
Publication number
20240076713
Publication date
Mar 7, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE...
Publication number
20240018544
Publication date
Jan 18, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE...
Publication number
20240011049
Publication date
Jan 11, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE...
Publication number
20240011050
Publication date
Jan 11, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISP...
Publication number
20230416310
Publication date
Dec 28, 2023
The General Hospital Corporation
Y. Esther Tak
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for...
Publication number
20230407341
Publication date
Dec 21, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20230407277
Publication date
Dec 21, 2023
The General Hospital Corporation
J. Keith Joung
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Systems and Methods for Stable and Heritable Alteration by Precisio...
Publication number
20230245716
Publication date
Aug 3, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENHANCED VIRUS-LIKE PARTICLES AND METHODS OF USE THEREOF FOR DELIVE...
Publication number
20230227793
Publication date
Jul 20, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEM AND METHOD FOR ACTIVATING GENE EXPRESSION
Publication number
20230036273
Publication date
Feb 2, 2023
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SPLIT DEAMINASE BASE EDITORS
Publication number
20230024833
Publication date
Jan 26, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20230021303
Publication date
Jan 19, 2023
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
C-to-G Transversion DNA Base Editors
Publication number
20220411777
Publication date
Dec 29, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Combinatorial Adenine and Cytosine DNA Base Editors
Publication number
20220290121
Publication date
Sep 15, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITORS WITH IMPROVED PRECISION AND SPECIFICITY
Publication number
20220275356
Publication date
Sep 1, 2022
The General Hospital Corporation
J. Keith JOUNG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED HUMAN-ENDOGENOUS VIRUS-LIKE PARTICLES AND METHODS OF USE...
Publication number
20220259617
Publication date
Aug 18, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity
Publication number
20220169998
Publication date
Jun 2, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity
Publication number
20220145275
Publication date
May 12, 2022
The General Hospital Corporation
J. Keith Joung
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins...
Publication number
20220090145
Publication date
Mar 24, 2022
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Publication number
20220025347
Publication date
Jan 27, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)
Publication number
20220017883
Publication date
Jan 20, 2022
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY