Manuel de Lera Ruiz

Person

Perkasie, PA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Phosphinic amide prodrugs of tenofovir
- Patent number 11,826,375
- Issue date Nov 28, 2023
- Merck Sharp & Dohme LLC
- Manuel De Lera Ruiz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antiviral benzyl-amine phosphodiamide compounds
- Patent number 11,123,355
- Issue date Sep 21, 2021
- Idenix Pharmaceuticals LLC
- Manuel de Lera Ruiz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
2,2-difluorodioxolo A2A receptor antagonists
- Patent number 11,046,714
- Issue date Jun 29, 2021
- Merck Sharp & Dohme Corp.
- Ali Amjad
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Aminoquinazoline compounds as A2A antagonist
- Patent number 10,138,212
- Issue date Nov 27, 2018
- Merck Sharp & Dohme Corp.
- Amjad Ali
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Biaryl-spiroaminooxzaoline analogues as alpha 2C adrenergic recepto...
- Patent number 8,569,312
- Issue date Oct 29, 2013
- Merck Sharp & Dohme Corp.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Functionally selective alpha2C adrenoreceptor agonists
- Patent number 8,501,747
- Issue date Aug 6, 2013
- Merck Sharp & Dohme Corp.
- Manuel de lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Biaryl spiroaminooxazoline analogues as Alpha2C adrenergic receptor...
- Patent number 8,476,274
- Issue date Jul 2, 2013
- Merck Sharp & Dohme Corp.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Biaryl-spiroaminooxazoline analogues as alpha 2C adrenergic recepto...
- Patent number 8,324,213
- Issue date Dec 4, 2012
- Merck Sharp & Dohme Corp.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
ALPHA2C adrenoreceptor agonists
- Patent number 7,985,748
- Issue date Jul 26, 2011
- Pharmacopeia Drug Discovery, Inc.
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted aniline derivatives useful as histamine H3 antagonists
- Patent number 7,879,880
- Issue date Feb 1, 2011
- Schering Corporation
- Daniel M. Solomon
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heteroatom-linked substituted piperidines and derivatives thereof u...
- Patent number 7,846,946
- Issue date Dec 7, 2010
- Schering-Plough Corporation
- Robert G. Aslanian
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
α2C adrenoreceptor agonists
- Patent number 7,700,592
- Issue date Apr 20, 2010
- Schering Corporation
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Phenoxypiperidines and analogs thereof useful as histamine H3 antag...
- Patent number 7,638,531
- Issue date Dec 29, 2009
- Schering Corporation
- Mwangi W. Mutahi
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heteroatom-linked substituted piperidines and derivatives thereof u...
- Patent number 7,635,705
- Issue date Dec 22, 2009
- Schering Corporation
- Robert G. Aslanian
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-[[1-[(2-amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...
- Patent number 7,531,660
- Issue date May 12, 2009
- Schering Corporation
- Manuel de Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...
- Patent number 7,332,604
- Issue date Feb 19, 2008
- Schering Corporation
- Manuel de Lera Ruiz
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION
- Publication number 20240228535
- Publication date Jul 11, 2024
- Merck Sharp & Dohme LLC
- John J. Acton
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY
- Publication number 20240076297
- Publication date Mar 7, 2024
- Merck Sharp & Dohme LLC
- Amjad Ali
- C07 - ORGANIC CHEMISTRY
Information Patent Application
POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PR...
- Publication number 20240018145
- Publication date Jan 18, 2024
- Merck Sharp & Dohme LLC
- Yonglian Zhang
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIMALARIAL AGENTS
- Publication number 20230139282
- Publication date May 4, 2023
- Merck Sharp & Dohme LLC
- Manuel de Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIMALARIAL AGENTS
- Publication number 20230013692
- Publication date Jan 19, 2023
- Merck Sharp & Dohme LLC
- John A. McCauley
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIMALARIAL AGENTS
- Publication number 20220331321
- Publication date Oct 20, 2022
- MERCK SHARP & DOHME CORP.
- John A. McCauley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHOSPHINIC AMIDE PRODRUGS OF TENOFOVIR
- Publication number 20210260082
- Publication date Aug 26, 2021
- MERCK SHARP & DOHME CORP.
- Manuel De Lera Ruiz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIVIRAL BENZYL-AMINE PHOSPHODIAMIDE COMPOUNDS
- Publication number 20190321380
- Publication date Oct 24, 2019
- MERCK SHARP & DOHME CORP.
- Manuel de Lera Ruiz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
AMINOQUINAZOLINE COMPOUNDS AS A2A ANTAGONIST
- Publication number 20180037554
- Publication date Feb 8, 2018
- MERCK SHARP & DOHME CORP.
- Amjad Ali
- C07 - ORGANIC CHEMISTRY
Information Patent Application
2,2-DIFLUORODIOXOLO A2A RECEPTOR ANTAGONISTS
- Publication number 20160214997
- Publication date Jul 28, 2016
- MERCK SHARP & DOHME CORP.
- Ali Amjad
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIARYL-SPIROAMINOOXZAOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTO...
- Publication number 20130225582
- Publication date Aug 29, 2013
- MERCK SHARP & DOHME CORP.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
REVERSED BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC...
- Publication number 20130079271
- Publication date Mar 28, 2013
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR...
- Publication number 20130045914
- Publication date Feb 21, 2013
- MERCK SHARP & DOHME CORP.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIARYL-SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTO...
- Publication number 20110251207
- Publication date Oct 13, 2011
- MERCK SHARP & DOHME CORP.
- Kevin D. McCormick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CYCLOPROPYLCHROMENE DERIVATIVES AS MODULATORS OF THE ALPHA-2C RECEPTOR
- Publication number 20110190247
- Publication date Aug 4, 2011
- Schering Corporation
- Younong Yu
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRICYCLIC SPIROCYCLE DERIVATIVES AND METHODS OF USE
- Publication number 20110166124
- Publication date Jul 7, 2011
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Tricyclic Heterocyclic Derivatives and Methods of Use
- Publication number 20110136790
- Publication date Jun 9, 2011
- Manuel De Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Bicyclic Heterocylic Derivatives and Methods of Use
- Publication number 20110130385
- Publication date Jun 2, 2011
- Manuel De Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS
- Publication number 20100197562
- Publication date Aug 5, 2010
- SCHERING CORPORATION AND PHARMACOPEIA, LLC
- Manuel De lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ALPHA2C ADRENORECEPTOR AGONISTS
- Publication number 20100173823
- Publication date Jul 8, 2010
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HETEROATOM-LINKED SUBSTITUTED PIPERIDINES AND DERIVATIVES THEREOF U...
- Publication number 20090286830
- Publication date Nov 19, 2009
- Schering Corporation
- Robert G. Aslanian
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...
- Publication number 20080058370
- Publication date Mar 6, 2008
- Schering Corporation
- Manuel de Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Alpha2C adrenoreceptor agonists
- Publication number 20080039439
- Publication date Feb 14, 2008
- Schering Corporation
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Phenoxypiperidines and analogs thereof useful as histamine H3 antag...
- Publication number 20070167435
- Publication date Jul 19, 2007
- Schering Corporation
- Mwangi W. Mutahi
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted aniline derivatives useful as histamine H3 antagonists
- Publication number 20070142394
- Publication date Jun 21, 2007
- Schering Corporation
- Daniel M. Solomon
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Alpha2C adrenoreceptor agonists
- Publication number 20070093477
- Publication date Apr 26, 2007
- Schering Corporation and Pharmacopeia Drug Discovery, Inc.
- Kevin D. McCormick
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...
- Publication number 20070066644
- Publication date Mar 22, 2007
- Schering Corporation
- Manuel de Lera Ruiz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Heteroatom-linked substituted piperidines and derivatives thereof u...
- Publication number 20070015807
- Publication date Jan 18, 2007
- Schering Corporation
- Robert G. Aslanian
- C07 - ORGANIC CHEMISTRY

Manuel de Lera Ruiz

Person

Patents Grantslast 30 patents

Phosphinic amide prodrugs of tenofovir

Antiviral benzyl-amine phosphodiamide compounds

2,2-difluorodioxolo A2A receptor antagonists

Aminoquinazoline compounds as A2A antagonist

Biaryl-spiroaminooxzaoline analogues as alpha 2C adrenergic recepto...

Functionally selective alpha2C adrenoreceptor agonists

Biaryl spiroaminooxazoline analogues as Alpha2C adrenergic receptor...

Biaryl-spiroaminooxazoline analogues as alpha 2C adrenergic recepto...

ALPHA2C adrenoreceptor agonists

Substituted aniline derivatives useful as histamine H3 antagonists

Heteroatom-linked substituted piperidines and derivatives thereof u...

α2C adrenoreceptor agonists

Phenoxypiperidines and analogs thereof useful as histamine H3 antag...

Heteroatom-linked substituted piperidines and derivatives thereof u...

1-[[1-[(2-amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...

1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...

Patents Applicationslast 30 patents

PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION

ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY

POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PR...

ANTIMALARIAL AGENTS

ANTIMALARIAL AGENTS

ANTIMALARIAL AGENTS

PHOSPHINIC AMIDE PRODRUGS OF TENOFOVIR

ANTIVIRAL BENZYL-AMINE PHOSPHODIAMIDE COMPOUNDS

AMINOQUINAZOLINE COMPOUNDS AS A2A ANTAGONIST

2,2-DIFLUORODIOXOLO A2A RECEPTOR ANTAGONISTS

BIARYL-SPIROAMINOOXZAOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTO...

REVERSED BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC...

BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR...

BIARYL-SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTO...

CYCLOPROPYLCHROMENE DERIVATIVES AS MODULATORS OF THE ALPHA-2C RECEPTOR

TRICYCLIC SPIROCYCLE DERIVATIVES AND METHODS OF USE

Tricyclic Heterocyclic Derivatives and Methods of Use

Bicyclic Heterocylic Derivatives and Methods of Use

FUNCTIONALLY SELECTIVE ALPHA2C ADRENORECEPTOR AGONISTS

ALPHA2C ADRENORECEPTOR AGONISTS

HETEROATOM-LINKED SUBSTITUTED PIPERIDINES AND DERIVATIVES THEREOF U...

1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...

Alpha2C adrenoreceptor agonists

Phenoxypiperidines and analogs thereof useful as histamine H3 antag...

Substituted aniline derivatives useful as histamine H3 antagonists

Alpha2C adrenoreceptor agonists

1-[[1-[(2-Amino-6-methyl-4-pyridinyl)methyl]-4-fluoro-4-piperidinyl...

Heteroatom-linked substituted piperidines and derivatives thereof u...