William Markland

Person

Southborough, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Method for treating cancer using a combination of DNA-damaging agen...
- Patent number 11,980,633
- Issue date May 14, 2024
- Vertex Pharmaceuticals Incorporated
- Diane Boucher
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for treating cancer using a combination of DNA-damaging agen...
- Patent number 11,110,108
- Issue date Sep 7, 2021
- Vertex Pharmaceuticals Incorporated
- Diane M. Boucher
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Kallikrein-binding “kunitz domain” proteins and analogues thereof
- Patent number 8,663,629
- Issue date Mar 4, 2014
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nucleic acids encoding polypeptide inhibitors of human plasmin deri...
- Patent number 8,431,359
- Issue date Apr 30, 2013
- Dyax Corp.
- William Markland
- C04 - CEMENTS CONCRETE ARTIFICIAL STONE CERAMICS REFRACTORIES
Information Patent Grant
Kallikrein-binding “Kunitz domain” proteins and analogues thereof
- Patent number 8,283,321
- Issue date Oct 9, 2012
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Crystallization of C-Jun N-Terminal Kinase 3 (JNK3)
- Patent number 8,002,891
- Issue date Aug 23, 2011
- Vertex Pharmaceuticals Incorporated
- Xiaoling Xie
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of human plasmin derived from the Kunitz domains
- Patent number 7,919,462
- Issue date Apr 5, 2011
- Dyax Corp.
- William Markland
- C04 - CEMENTS CONCRETE ARTIFICIAL STONE CERAMICS REFRACTORIES
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 7,893,007
- Issue date Feb 22, 2011
- Dyax Corp.
- Robert Charles Ladner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nucleic acids encoding polypeptide inhibitors of human plasmin deri...
- Patent number 7,736,867
- Issue date Jun 15, 2010
- Dyax Corp.
- William Markland
Information Patent Grant
Kallikrein-binding “Kunitz domain” proteins and analogues thereof
- Patent number 7,628,983
- Issue date Dec 8, 2009
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Directed evolution of disulfide-bonded micro-proteins
- Patent number 7,413,537
- Issue date Aug 19, 2008
- Dyax Corp.
- Robert Charles Ladner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of designing inhibitors for JNK kinases
- Patent number 7,383,135
- Issue date Jun 3, 2008
- Vertex Pharmaceuticals Incorporated
- Xiaoling Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 7,208,293
- Issue date Apr 24, 2007
- Dyax Corp.
- Robert Charles Ladner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method of recovering a nucleic acid encoding a proteinaceous bindin...
- Patent number 7,118,879
- Issue date Oct 10, 2006
- Dyax Corp.
- Robert Charles Ladner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
ITI-D1 Kunitz domain mutants as HNE inhibitors
- Patent number 7,078,383
- Issue date Jul 18, 2006
- Dyax Corp.
- Arthur C Ley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 6,979,538
- Issue date Dec 27, 2005
- Dyax Corp.
- Robert Charles Ladner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Inhibitors of human plasmin derived from the kunitz domains
- Patent number 6,953,674
- Issue date Oct 11, 2005
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Variegated Kunitz domain peptide library and uses thereof
- Patent number 6,423,498
- Issue date Jul 23, 2002
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Kallikrein-binding “Kunitz domain” proteins and ana...
- Patent number 6,333,402
- Issue date Dec 25, 2001
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of human plasmin derived from the Kunitz domains
- Patent number 6,103,499
- Issue date Aug 15, 2000
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of human plasmin derived from the Kunitz domains
- Patent number 6,071,723
- Issue date Jun 6, 2000
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
- Patent number 6,057,287
- Issue date May 2, 2000
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of human plasmin derived from the kunitz domains
- Patent number 6,010,880
- Issue date Jan 4, 2000
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 5,837,500
- Issue date Nov 17, 1998
- Dyax, Corp.
- Robert Charles Ladner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered human-derived kunitz domains that inhibit human neutroph...
- Patent number 5,663,143
- Issue date Sep 2, 1997
- Dyax Corp.
- Arthur Charles Ley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 5,571,698
- Issue date Nov 5, 1996
- Protein Engineering Corporation
- Robert C. Ladner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Viruses expressing chimeric binding proteins
- Patent number 5,403,484
- Issue date Apr 4, 1995
- Protein Engineering Corporation
- Robert C. Ladner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Directed evolution of novel binding proteins
- Patent number 5,223,409
- Issue date Jun 29, 1993
- Protein Engineering Corp.
- Robert C. Ladner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
METHOD FOR TREATING CANCER USING A COMBINATION OF DNA-DAMAGING AGEN...
- Publication number 20220088043
- Publication date Mar 24, 2022
- VERTEX PHARMACEUTICALS INCORPORATED
- Diane Boucher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD FOR TREATING CANCER USING A COMBINATION OF DNA-DAMAGING AGEN...
- Publication number 20200016181
- Publication date Jan 16, 2020
- VERTEX PHARMACEUTICALS INCORPORATED
- Diane M. Boucher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
KALLIKREIN-BINDING "KUNITZ DOMAIN" PROTEINS AND ANALOGUES THEREOF
- Publication number 20120328517
- Publication date Dec 27, 2012
- Dyax Corp.
- William Markland
- G01 - MEASURING TESTING
Information Patent Application
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS
- Publication number 20110152193
- Publication date Jun 23, 2011
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Kallikrein-Binding "Kunitz Domain" Proteins and Analogues Thereof
- Publication number 20110136746
- Publication date Jun 9, 2011
- Dyax Corp.
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS
- Publication number 20090234101
- Publication date Sep 17, 2009
- Dyax Corp.
- ROBERT CHARLES LADNER
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Crystallizable JNK complexes
- Publication number 20090186394
- Publication date Jul 23, 2009
- Vertex Pharmaceuticals Incorporated.
- Xiaoling Xie
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS
- Publication number 20090036365
- Publication date Feb 5, 2009
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS
- Publication number 20090036366
- Publication date Feb 5, 2009
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS
- Publication number 20090023651
- Publication date Jan 22, 2009
- Dyax Copr., a Delaware corporation
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS
- Publication number 20080182283
- Publication date Jul 31, 2008
- Dyax Corp.
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS
- Publication number 20070259417
- Publication date Nov 8, 2007
- Dyax Corp.
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
- Publication number 20060264603
- Publication date Nov 23, 2006
- William Markland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ITI-D1 Kunitz domain mutants as hNE inhibitors
- Publication number 20060134087
- Publication date Jun 22, 2006
- Dyax Corp.
- Arthur Charles Ley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Directed evolution of disulfide-bonded micro-proteins
- Publication number 20060084113
- Publication date Apr 20, 2006
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Inhibitors of human plasmin derived from the kunitz domains
- Publication number 20050186649
- Publication date Aug 25, 2005
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Method of recovering a nucleic acid encoding a proteinaceous bindin...
- Publication number 20040023205
- Publication date Feb 5, 2004
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Nucleic acids, genetic constructs, and library of nucleic acids enc...
- Publication number 20040005539
- Publication date Jan 8, 2004
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Kunitz domain mutants as cathepsin G inhibitors
- Publication number 20030223977
- Publication date Dec 4, 2003
- Arthur Charles Ley
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Directed evolution of novel binding proteins
- Publication number 20030219886
- Publication date Nov 27, 2003
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Fusion proteins, modified filamentous bacteriophage, and population...
- Publication number 20030219722
- Publication date Nov 27, 2003
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
ITI-D1 Kunitz domain mutants as hNE inhibitors
- Publication number 20030175919
- Publication date Sep 18, 2003
- Arthur Charles Ley
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Inhibitors of human plasmin derived from the kunitz domains
- Publication number 20030165896
- Publication date Sep 4, 2003
- William Markland
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Directed evolution of novel binding proteins
- Publication number 20030113717
- Publication date Jun 19, 2003
- Robert Charles Ladner
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
Directed evolution of novel binding proteins
- Publication number 20020150881
- Publication date Oct 17, 2002
- Robert Charles Ladner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

William Markland

Person

Patents Grantslast 30 patents

Method for treating cancer using a combination of DNA-damaging agen...

Method for treating cancer using a combination of DNA-damaging agen...

Kallikrein-binding “kunitz domain” proteins and analogues thereof

Nucleic acids encoding polypeptide inhibitors of human plasmin deri...

Kallikrein-binding “Kunitz domain” proteins and analogues thereof

Crystallization of C-Jun N-Terminal Kinase 3 (JNK3)

Inhibitors of human plasmin derived from the Kunitz domains

Directed evolution of novel binding proteins

Nucleic acids encoding polypeptide inhibitors of human plasmin deri...

Kallikrein-binding “Kunitz domain” proteins and analogues thereof

Directed evolution of disulfide-bonded micro-proteins

Methods of designing inhibitors for JNK kinases

Directed evolution of novel binding proteins

Method of recovering a nucleic acid encoding a proteinaceous bindin...

ITI-D1 Kunitz domain mutants as HNE inhibitors

Directed evolution of novel binding proteins

Inhibitors of human plasmin derived from the kunitz domains

Variegated Kunitz domain peptide library and uses thereof

Kallikrein-binding &#x0201C;Kunitz domain&#x0201D; proteins and ana...

Inhibitors of human plasmin derived from the Kunitz domains

Inhibitors of human plasmin derived from the Kunitz domains

Kallikrein-binding "Kunitz domain" proteins and analogues thereof

Inhibitors of human plasmin derived from the kunitz domains

Directed evolution of novel binding proteins

Engineered human-derived kunitz domains that inhibit human neutroph...

Directed evolution of novel binding proteins

Viruses expressing chimeric binding proteins

Directed evolution of novel binding proteins

Patents Applicationslast 30 patents

METHOD FOR TREATING CANCER USING A COMBINATION OF DNA-DAMAGING AGEN...

METHOD FOR TREATING CANCER USING A COMBINATION OF DNA-DAMAGING AGEN...

KALLIKREIN-BINDING "KUNITZ DOMAIN" PROTEINS AND ANALOGUES THEREOF

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

Kallikrein-Binding "Kunitz Domain" Proteins and Analogues Thereof

DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS

Crystallizable JNK complexes

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS

Kallikrein-binding "Kunitz domain" proteins and analogues thereof

ITI-D1 Kunitz domain mutants as hNE inhibitors

Directed evolution of disulfide-bonded micro-proteins

Inhibitors of human plasmin derived from the kunitz domains

Method of recovering a nucleic acid encoding a proteinaceous bindin...

Nucleic acids, genetic constructs, and library of nucleic acids enc...

Kunitz domain mutants as cathepsin G inhibitors

Directed evolution of novel binding proteins

Fusion proteins, modified filamentous bacteriophage, and population...

ITI-D1 Kunitz domain mutants as hNE inhibitors

Inhibitors of human plasmin derived from the kunitz domains

Directed evolution of novel binding proteins

Directed evolution of novel binding proteins

Kallikrein-binding “Kunitz domain” proteins and ana...