2'-O-R Modification

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CPC
C12N2310/321

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

Current Industry

C12N2310/3212'-O-R Modification

Industries

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Patents Grantslast 30 patents

Information Patent Grant
RNAi agents for inhibiting expression of mucin 5AC (MUC5AC), compos...
- Patent number 12,365,897
- Issue date Jul 22, 2025
- Arrowhead Pharmaceuticals, Inc.
- Erik W. Bush
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNAi agents and compositions for inhibiting expression of apolipopr...
- Patent number 12,365,899
- Issue date Jul 22, 2025
- Arrowhead Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Branched lipid conjugates of siRNA for specific tissue delivery
- Patent number 12,365,894
- Issue date Jul 22, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Complement component C3 iRNA compositions and methods of use thereof
- Patent number 12,365,896
- Issue date Jul 22, 2025
- Alnylam Pharmaceuticals, Inc.
- Mark Keating
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
17ß-hydroxysteroid dehydrogenase type 13 (HSD17B13) iRNA compositio...
- Patent number 12,359,201
- Issue date Jul 15, 2025
- REGENERON PHARMACEUTICALS, INC.
- Gregory Hinkle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Transgene cassettes designed to express a human MECP2 gene
- Patent number 12,359,219
- Issue date Jul 15, 2025
- The Board of Regents of the University of Texas System
- Steven J. Gray
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing ATXN3 expression
- Patent number 12,350,285
- Issue date Jul 8, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid-polypeptide compositions and uses thereof
- Patent number 12,351,637
- Issue date Jul 8, 2025
- AVIDITY BIOSCIENCES, INC.
- Andrew John Geall
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions of asymmetric interfering RNA and uses thereof
- Patent number 12,344,840
- Issue date Jul 1, 2025
- 1GLOBE HEALTH INSTITUTE LLC
- Chiang Jia Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,344,839
- Issue date Jul 1, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher f...
- Patent number 12,338,439
- Issue date Jun 24, 2025
- Alnylam Pharmaceuticals, Inc.
- Akin Akinc
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
OPA1 antisense oligomers for treatment of conditions and diseases
- Patent number 12,338,437
- Issue date Jun 24, 2025
- Stoke Therapeutics, Inc.
- Isabel Aznarez
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified nucleic acids, hybrid guide RNAS, and uses thereof
- Patent number 12,338,433
- Issue date Jun 24, 2025
- OHIO STATE INNOVATION FOUNDATION
- Yizhou Dong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific antisense oligonucleotides for dystrophin exon skipping
- Patent number 12,331,293
- Issue date Jun 17, 2025
- BIOMARIN TECHNOLOGIES B.V.
- Judith Christina Theodora van Deutekom
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions, systems, and methods for regulation of Hepatitis b vi...
- Patent number 12,325,857
- Issue date Jun 10, 2025
- TUNE THERAPEUTICS, INC.
- Brian Cosgrove
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions, systems, and methods for regulation of Hepatitis B vi...
- Patent number 12,325,858
- Issue date Jun 10, 2025
- TUNE THERAPEUTICS, INC.
- Brian Cosgrove
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for modulating gene expression using oligo...
- Patent number 12,319,914
- Issue date Jun 3, 2025
- Larry J. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for targeting, editing, or modifying genes
- Patent number 12,319,932
- Issue date Jun 3, 2025
- Celyntra Therapeutics SA
- Andrea Barghetti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides targeting frataxin and related methods
- Patent number 12,312,585
- Issue date May 27, 2025
- UNIVERSITY OF MASSACHUSETTS
- Feng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Treatment of MST1 related diseases and disorders
- Patent number 12,312,586
- Issue date May 27, 2025
- EMPIRICO INC.
- Omri Gottesman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides for the treatment of nucleotide repeat expansion d...
- Patent number 12,297,432
- Issue date May 13, 2025
- Takeda Pharmaceuticals U.S.A., Inc.
- Nessan Anthony Bermingham
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modulation of huntingtin expression
- Patent number 12,297,431
- Issue date May 13, 2025
- Ionis Pharmaceuticals, Inc.
- Gene Hung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,297,429
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
O-methyl rich fully stabilized oligonucleotides
- Patent number 12,297,430
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
- Patent number 12,291,709
- Issue date May 6, 2025
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified RNAi agents
- Patent number 12,290,573
- Issue date May 6, 2025
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oral delivery of antisense conjugates targeting PCSK9
- Patent number 12,291,708
- Issue date May 6, 2025
- CiVi Biopharma, Inc.
- Henrik Oerum
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antisense oligonucleotide targeting ATN1 mRNA or pre-mRNA
- Patent number 12,291,710
- Issue date May 6, 2025
- Nippon Shinyaku Co., Ltd.
- Takao Kawano
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibition of mir-22 miRNA by APT-110
- Patent number 12,286,625
- Issue date Apr 29, 2025
- APTAMIR THERAPEUTICS, INC.
- Marc Thibonnier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing prion expression
- Patent number 12,281,305
- Issue date Apr 22, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASES WITH SIRNAS TA...
- Publication number 20250236868
- Publication date Jul 24, 2025
- The Board of Regents of the University of Texas System
- Hao Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Nucleic acids for inhibiting expression of MASP-2 in a cell
- Publication number 20250230441
- Publication date Jul 17, 2025
- Silence Therapeutics GMBH
- Eliot Morrison
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASES WITH SIRNAS TA...
- Publication number 20250228885
- Publication date Jul 17, 2025
- The Board of Regents of the University of Texas System
- Hao Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Selective Reduction of Allelic Variants
- Publication number 20250223589
- Publication date Jul 10, 2025
- Ionis Pharmaceuticals, Inc.
- C. Frank Bennett
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INSULIN RECEPTOR-BINDING APTAMER DIMER AND USE THEREOF
- Publication number 20250223600
- Publication date Jul 10, 2025
- POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
- Sung Ho RYU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULE, MODIFIED DOUBLE-...
- Publication number 20250223594
- Publication date Jul 10, 2025
- RIGERNA THERAPEUTICS (BEIJING) CO., LTD.
- Yuanyu Huang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYF2 ANTISENSE OLIGONUCLEOTIDES
- Publication number 20250223591
- Publication date Jul 10, 2025
- AcuraStem Incorported
- Emily Elizabeth LEE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES
- Publication number 20250223588
- Publication date Jul 10, 2025
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TARGETED CELL SELECTION AND RELEASE USING APTAMER COMPLEXES IN A CE...
- Publication number 20250215386
- Publication date Jul 3, 2025
- Trenchant BioSystems, Inc.
- Jonathan Ellis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED RNAi AGENTS
- Publication number 20250213720
- Publication date Jul 3, 2025
- Kallanthottathil G. RAJEEV
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BRANCHED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS
- Publication number 20250215432
- Publication date Jul 3, 2025
- Novartis AG
- Charles ALLERSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODULATION OF HEPATITIS B VIRUS (HBV) EXPRESSION
- Publication number 20250215430
- Publication date Jul 3, 2025
- AUSPERBIO THERAPEUTICS INC.
- Guofeng CHENG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Compositions and Methods for TTR Gene Editing and Treating ATTR Amy...
- Publication number 20250207130
- Publication date Jun 26, 2025
- INTELLIA THERAPEUTICS, INC.
- Arti Mahendra Prakash Kanjolia
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...
- Publication number 20250207138
- Publication date Jun 26, 2025
- Amgen Inc.
- Bryan MEADE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kina...
- Publication number 20250207139
- Publication date Jun 26, 2025
- Arrowhead Pharmaceuticals, Inc.
- Michelle Ngai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF FOR EXON SKIPPING
- Publication number 20250197857
- Publication date Jun 19, 2025
- WAVE LIFE SCIENCES LTD.
- Xiao Shelley Hu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SIRNA TARGETING ANGIOTENSINOGEN AND PHARMACEUTICAL USE OF SIRNA
- Publication number 20250197853
- Publication date Jun 19, 2025
- Tuojie Biotech (Shanghai) Co., Ltd.
- Xiaoyan LIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION OF ALPHA-1...
- Publication number 20250197861
- Publication date Jun 19, 2025
- Arrowhead Pharmaceuticals, Inc.
- Christine I. Wooddell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LNCRNA TRANSCRIPTS IN MELANOMAGENESIS
- Publication number 20250197864
- Publication date Jun 19, 2025
- The Regents of the University of California
- Susana Ortiz Urda
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
EXPONENTIAL BASE-3 AND GREATER NUCLEIC ACID AMPLIFICATION WITH REDU...
- Publication number 20250197850
- Publication date Jun 19, 2025
- Cepheid
- Russell HIGUCHI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (...
- Publication number 20250197859
- Publication date Jun 19, 2025
- EMPIRICO INC.
- Omri GOTTESMAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUNDS AND METHODS FOR REDUCING IFNAR1 EXPRESSION
- Publication number 20250188476
- Publication date Jun 12, 2025
- Ionis Pharmaceuticals, Inc.
- Fredrik Carl Kamme
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
siRNA SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR 2
- Publication number 20250188478
- Publication date Jun 12, 2025
- DAIICHI SANKYO COMPANY, LIMITED
- Makoto KOIZUMI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA...
- Publication number 20250191692
- Publication date Jun 12, 2025
- Switch Therapeutics Inc.
- Si-ping Han
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTISENSE OLIGONUCLEOTIDES FOR TARGETING PROGRANULIN
- Publication number 20250188462
- Publication date Jun 12, 2025
- HOFFMANN-LA ROCHE INC.
- Jesper WORM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYNUCLEIC ACID MOLECULES FOR INHIBITING EXPRESSION OF LP(A), PHAR...
- Publication number 20250188464
- Publication date Jun 12, 2025
- Sirius Therapeutics, Inc.
- Curt BRADSHAW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOME...
- Publication number 20250188470
- Publication date Jun 12, 2025
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NONCOVALENTLY BRANCHED OLIGONUCLEOTIDE COMPOSITIONS
- Publication number 20250188471
- Publication date Jun 12, 2025
- Atalanta Therapeutics, Inc.
- Matthew HASSLER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20250188475
- Publication date Jun 12, 2025
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES
- Publication number 20250188453
- Publication date Jun 12, 2025
- Switch Therapeutics Inc.
- Si-ping Han
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

2'-O-R Modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

RNAi agents for inhibiting expression of mucin 5AC (MUC5AC), compos...

RNAi agents and compositions for inhibiting expression of apolipopr...

Branched lipid conjugates of siRNA for specific tissue delivery

Complement component C3 iRNA compositions and methods of use thereof

17ß-hydroxysteroid dehydrogenase type 13 (HSD17B13) iRNA compositio...

Transgene cassettes designed to express a human MECP2 gene

Compounds and methods for reducing ATXN3 expression

Nucleic acid-polypeptide compositions and uses thereof

Compositions of asymmetric interfering RNA and uses thereof

Dual-acting siRNA based modulation of C9orf72

Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher f...

OPA1 antisense oligomers for treatment of conditions and diseases

Modified nucleic acids, hybrid guide RNAS, and uses thereof

Bispecific antisense oligonucleotides for dystrophin exon skipping

Compositions, systems, and methods for regulation of Hepatitis b vi...

Compositions, systems, and methods for regulation of Hepatitis B vi...

Methods and compositions for modulating gene expression using oligo...

Compositions and methods for targeting, editing, or modifying genes

Oligonucleotides targeting frataxin and related methods

Treatment of MST1 related diseases and disorders

Oligonucleotides for the treatment of nucleotide repeat expansion d...

Modulation of huntingtin expression

Dual-acting siRNA based modulation of C9orf72

O-methyl rich fully stabilized oligonucleotides

Compositions and methods for modulating apolipoprotein (a) expression

Modified RNAi agents

Oral delivery of antisense conjugates targeting PCSK9

Antisense oligonucleotide targeting ATN1 mRNA or pre-mRNA

Inhibition of mir-22 miRNA by APT-110

Compounds and methods for reducing prion expression

Patents Applicationslast 30 patents

COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASES WITH SIRNAS TA...

Nucleic acids for inhibiting expression of MASP-2 in a cell

COMPOSITIONS AND METHODS FOR TREATING LIVER DISEASES WITH SIRNAS TA...

Selective Reduction of Allelic Variants

INSULIN RECEPTOR-BINDING APTAMER DIMER AND USE THEREOF

MODIFIED DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULE, MODIFIED DOUBLE-...

SYF2 ANTISENSE OLIGONUCLEOTIDES

OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES

TARGETED CELL SELECTION AND RELEASE USING APTAMER COMPLEXES IN A CE...

MODIFIED RNAi AGENTS

BRANCHED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS

MODULATION OF HEPATITIS B VIRUS (HBV) EXPRESSION

Compositions and Methods for TTR Gene Editing and Treating ATTR Amy...

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...

RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kina...

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF FOR EXON SKIPPING

SIRNA TARGETING ANGIOTENSINOGEN AND PHARMACEUTICAL USE OF SIRNA

COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION OF ALPHA-1...

LNCRNA TRANSCRIPTS IN MELANOMAGENESIS

EXPONENTIAL BASE-3 AND GREATER NUCLEIC ACID AMPLIFICATION WITH REDU...

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (...

COMPOUNDS AND METHODS FOR REDUCING IFNAR1 EXPRESSION

siRNA SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR 2

METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA...

ANTISENSE OLIGONUCLEOTIDES FOR TARGETING PROGRANULIN

POLYNUCLEIC ACID MOLECULES FOR INHIBITING EXPRESSION OF LP(A), PHAR...

MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOME...

NONCOVALENTLY BRANCHED OLIGONUCLEOTIDE COMPOSITIONS

KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES