2'-O-R Modification

Industry

CPC
C12N2310/321

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

Current Industry

C12N2310/3212'-O-R Modification

Industries

Patents Grantslast 30 patents

Information Patent Grant
Oligonucleotides targeting frataxin and related methods
- Patent number 12,312,585
- Issue date May 27, 2025
- UNIVERSITY OF MASSACHUSETTS
- Feng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Treatment of MST1 related diseases and disorders
- Patent number 12,312,586
- Issue date May 27, 2025
- EMPIRICO INC.
- Omri Gottesman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides for the treatment of nucleotide repeat expansion d...
- Patent number 12,297,432
- Issue date May 13, 2025
- Takeda Pharmaceuticals U.S.A., Inc.
- Nessan Anthony Bermingham
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modulation of huntingtin expression
- Patent number 12,297,431
- Issue date May 13, 2025
- Ionis Pharmaceuticals, Inc.
- Gene Hung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,297,429
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
O-methyl rich fully stabilized oligonucleotides
- Patent number 12,297,430
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
- Patent number 12,291,709
- Issue date May 6, 2025
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified RNAi agents
- Patent number 12,290,573
- Issue date May 6, 2025
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oral delivery of antisense conjugates targeting PCSK9
- Patent number 12,291,708
- Issue date May 6, 2025
- CiVi Biopharma, Inc.
- Henrik Oerum
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antisense oligonucleotide targeting ATN1 mRNA or pre-mRNA
- Patent number 12,291,710
- Issue date May 6, 2025
- Nippon Shinyaku Co., Ltd.
- Takao Kawano
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibition of mir-22 miRNA by APT-110
- Patent number 12,286,625
- Issue date Apr 29, 2025
- APTAMIR THERAPEUTICS, INC.
- Marc Thibonnier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing prion expression
- Patent number 12,281,305
- Issue date Apr 22, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid, composition and conjugate containing same, preparatio...
- Patent number 12,274,752
- Issue date Apr 15, 2025
- Suzhou Ribo Life Science Co., Ltd.
- Hongyan Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conjugated antisense compounds and their use
- Patent number 12,275,940
- Issue date Apr 15, 2025
- Ionis Pharmaceuticals, Inc.
- Michael Oestergaard
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for targeting, editing, or modifying genes
- Patent number 12,270,043
- Issue date Apr 8, 2025
- Celyntra Therapeutics SA
- Andrea Barghetti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
LAG3 binding peptides
- Patent number 12,269,880
- Issue date Apr 8, 2025
- Leidos, Inc.
- Gabriel M. Gutierrez
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Oligonucleotides for inducing paternal UBE3A expression
- Patent number 12,259,380
- Issue date Mar 25, 2025
- HOFFMANN-LA ROCHE INC.
- Veronica Costa
- G01 - MEASURING TESTING
Information Patent Grant
Complement component C3 iRNA compositions and methods of use thereof
- Patent number 12,258,565
- Issue date Mar 25, 2025
- Alnylam Pharmaceuticals, Inc.
- Mark Keating
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified oligonucleotides
- Patent number 12,258,563
- Issue date Mar 25, 2025
- EMPIRICO INC.
- Darren H. Wakefield
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting LPA expression
- Patent number 12,252,691
- Issue date Mar 18, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions, systems, and methods for regulation of hepatitis B vi...
- Patent number 12,252,692
- Issue date Mar 18, 2025
- TUNE THERAPEUTICS, INC.
- Brian Cosgrove
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
FN3 domain-siRNA conjugates and uses thereof
- Patent number 12,239,710
- Issue date Mar 4, 2025
- ARO BIOTHERAPEUTICS COMPANY
- Swapnil Kulkarni
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing LRRK2 expression
- Patent number 12,241,067
- Issue date Mar 4, 2025
- Ionis Pharmaceuticals, Inc.
- Tracy A. Cole
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified messenger RNA comprising functional RNA elements
- Patent number 12,241,063
- Issue date Mar 4, 2025
- ModernaTX, Inc.
- Melissa J. Moore
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic oligonucleotides
- Patent number 12,234,455
- Issue date Feb 25, 2025
- IFOM Fondazione Istituto FIRC di Oncologia Molecolare
- Fabrizio d′Adda di Fagagna
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid-polypeptide compositions and uses thereof
- Patent number 12,234,290
- Issue date Feb 25, 2025
- AVIDITY BIOSCIENCES, INC.
- Andrew John Geall
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating APOC3 expression
- Patent number 12,234,456
- Issue date Feb 25, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for inhibiting expression of transthyretin
- Patent number 12,227,744
- Issue date Feb 18, 2025
- Alnylam Pharmaceuticals, Inc.
- Dinah Wen-Yee Sah
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions, systems, and methods for regulation of hepatitis b vi...
- Patent number 12,221,608
- Issue date Feb 11, 2025
- TUNE THERAPEUTICS, INC.
- Brian Cosgrove
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Acetylated ribonucleic acids and uses thereof
- Patent number 12,215,317
- Issue date Feb 4, 2025
- Helix Nanotechnologies Inc
- Nikhil Dhar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
COMPOUND FOR INHIBITING C3 GENE EXPRESSION, PHARMACEUTICAL COMPOSIT...
- Publication number 20250161464
- Publication date May 22, 2025
- RIGERNA THERAPEUTICS (SUZHOU) CO., LTD.
- Yuanyu HUANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODIFIED TRANSFER RNA WITH IMPROVED ACTIVITY
- Publication number 20250163409
- Publication date May 22, 2025
- hC Bioscience, Inc.
- David H. Altreuter
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
THERAPEUTIC COMPOSITIONS FOR TREATING PAIN VIA MULTIPLE TARGETS
- Publication number 20250163419
- Publication date May 22, 2025
- QUELLTX, INC.
- Graham T. Dempsey
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITION FOR PREVENTION OR TREATMENT OF LIVER CANCER, COMPRISING...
- Publication number 20250163412
- Publication date May 22, 2025
- NEORNAT
- Suk-Woo NAM
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTISENSE OLIGONUCLEOTIDES FOR INDUCING EXON SKIPPING AND METHODS O...
- Publication number 20250163414
- Publication date May 22, 2025
- THE UNIVERSITY OF WESTERN AUSTRALIA
- Stephen Donald Wilton
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BASE EDITING OF ANGPTL3 AND METHODS OF USING SAME FOR TREATMENT OF...
- Publication number 20250152746
- Publication date May 15, 2025
- Verve Therapeutics, Inc.
- Alexandra Chadwick
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD
- Publication number 20250154507
- Publication date May 15, 2025
- Sarepta Therapeutics, Inc.
- Peter SAZANI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...
- Publication number 20250154512
- Publication date May 15, 2025
- Amgen Inc.
- Ingrid RULIFSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES WITH ETHYLENE GLYCOL MODIFICATION
- Publication number 20250145992
- Publication date May 8, 2025
- University of Massachusetts
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Antisense Nucleic Acids
- Publication number 20250145997
- Publication date May 8, 2025
- Nippon Shinyaku co., Ltd.
- Tatsushi Wakayama
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES TARGETING RNA BINDING PROTEIN SITES
- Publication number 20250145996
- Publication date May 8, 2025
- HOFFMANN-LA ROCHE INC.
- Jessica Marine Aurore BASTIEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF
- Publication number 20250135036
- Publication date May 1, 2025
- WAVE LIFE SCIENCES LTD.
- Christopher Michael Acker
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
iRNA Compositions and Methods for Silencing ANGPTL4
- Publication number 20250136978
- Publication date May 1, 2025
- Alnylam Pharmaceuticals, Inc.
- JEFFREY ZUBER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods and Compositions for Avoiding Off-Target Effects
- Publication number 20250136979
- Publication date May 1, 2025
- REGULUS THERAPEUTICS INC.
- Denis Drygin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODULATORS OF MALAT1 EXPRESSION
- Publication number 20250136986
- Publication date May 1, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
- Publication number 20250136995
- Publication date May 1, 2025
- DUKE UNIVERSITY
- Jennifer Freedman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VI...
- Publication number 20250136989
- Publication date May 1, 2025
- Tune Therapeutics, Inc.
- Brian COSGROVE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF
- Publication number 20250129364
- Publication date Apr 24, 2025
- Helix Nanotechnologies Inc
- Nikhil Dhar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VI...
- Publication number 20250129369
- Publication date Apr 24, 2025
- Tune Therapeutics, Inc.
- Brian COSGROVE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PREPARING CAPPED CIRCULAR RNA MOLECULES
- Publication number 20250129400
- Publication date Apr 24, 2025
- THE BROAD INSTITUTE, INC.
- Xiao WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR REDUCING HEPATIC TRIGLYCERIDES
- Publication number 20250129370
- Publication date Apr 24, 2025
- ADAERATA, LIMITED PARTNERSHIP
- Nabil G. SEIDAH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi OLIGONUCLEOTIDE CONJUGATES
- Publication number 20250122500
- Publication date Apr 17, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR GENE MODIFICATION
- Publication number 20250122534
- Publication date Apr 17, 2025
- VOR BIOPHARMA INC.
- Tirtha Chakraborty
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
- Publication number 20250122505
- Publication date Apr 17, 2025
- Alnyiam Pharmaceuticals, Inc.
- Brian Bettencourt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Bifunctional Molecules and Methods of Using Thereof
- Publication number 20250122502
- Publication date Apr 17, 2025
- Flagship Pioneering, Inc.
- Nathan Wilson Stebbins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMBINATIONS WITH MODULATORS OF PNPLA3 EXPRESSION
- Publication number 20250122504
- Publication date Apr 17, 2025
- AstraZeneca AB
- Daniel LINDÉN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED ADENYLATE KINASE VARIANTS
- Publication number 20250122488
- Publication date Apr 17, 2025
- Codexis, Inc.
- Stephanie Marie Forget
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUNDS FOR INHIBITION OF IL-1BETA EXPRESSION
- Publication number 20250115914
- Publication date Apr 10, 2025
- LEMBA BV
- Makiri Kawasaki
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20250115915
- Publication date Apr 10, 2025
- ADARx Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION
- Publication number 20250116656
- Publication date Apr 10, 2025
- HOFFMANN-LA ROCHE INC.
- Veronica COSTA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

2'-O-R Modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Oligonucleotides targeting frataxin and related methods

Treatment of MST1 related diseases and disorders

Oligonucleotides for the treatment of nucleotide repeat expansion d...

Modulation of huntingtin expression

Dual-acting siRNA based modulation of C9orf72

O-methyl rich fully stabilized oligonucleotides

Compositions and methods for modulating apolipoprotein (a) expression

Modified RNAi agents

Oral delivery of antisense conjugates targeting PCSK9

Antisense oligonucleotide targeting ATN1 mRNA or pre-mRNA

Inhibition of mir-22 miRNA by APT-110

Compounds and methods for reducing prion expression

Nucleic acid, composition and conjugate containing same, preparatio...

Conjugated antisense compounds and their use

Compositions and methods for targeting, editing, or modifying genes

LAG3 binding peptides

Oligonucleotides for inducing paternal UBE3A expression

Complement component C3 iRNA compositions and methods of use thereof

Modified oligonucleotides

Compositions and methods for inhibiting LPA expression

Compositions, systems, and methods for regulation of hepatitis B vi...

FN3 domain-siRNA conjugates and uses thereof

Compounds and methods for reducing LRRK2 expression

Modified messenger RNA comprising functional RNA elements

Therapeutic oligonucleotides

Nucleic acid-polypeptide compositions and uses thereof

Compositions and methods for modulating APOC3 expression

Compositions and methods for inhibiting expression of transthyretin

Compositions, systems, and methods for regulation of hepatitis b vi...

Acetylated ribonucleic acids and uses thereof

Patents Applicationslast 30 patents

COMPOUND FOR INHIBITING C3 GENE EXPRESSION, PHARMACEUTICAL COMPOSIT...

MODIFIED TRANSFER RNA WITH IMPROVED ACTIVITY

THERAPEUTIC COMPOSITIONS FOR TREATING PAIN VIA MULTIPLE TARGETS

COMPOSITION FOR PREVENTION OR TREATMENT OF LIVER CANCER, COMPRISING...

ANTISENSE OLIGONUCLEOTIDES FOR INDUCING EXON SKIPPING AND METHODS O...

BASE EDITING OF ANGPTL3 AND METHODS OF USING SAME FOR TREATMENT OF...

MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...

OLIGONUCLEOTIDES WITH ETHYLENE GLYCOL MODIFICATION

Antisense Nucleic Acids

OLIGONUCLEOTIDES TARGETING RNA BINDING PROTEIN SITES

COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF

iRNA Compositions and Methods for Silencing ANGPTL4

Methods and Compositions for Avoiding Off-Target Effects

MODULATORS OF MALAT1 EXPRESSION

SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE

COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VI...

ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF

COMPOSITIONS, SYSTEMS, AND METHODS FOR REGULATION OF HEPATITIS B VI...

COMPOSITIONS AND METHODS FOR PREPARING CAPPED CIRCULAR RNA MOLECULES

METHOD FOR REDUCING HEPATIC TRIGLYCERIDES

RNAi OLIGONUCLEOTIDE CONJUGATES

COMPOSITIONS AND METHODS FOR GENE MODIFICATION

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

Bifunctional Molecules and Methods of Using Thereof

COMBINATIONS WITH MODULATORS OF PNPLA3 EXPRESSION

ENGINEERED ADENYLATE KINASE VARIANTS

COMPOUNDS FOR INHIBITION OF IL-1BETA EXPRESSION

PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF

OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION