2'-R Modification

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CPC
C12N2310/322

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

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C12N2310/3222'-R Modification

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Patents Grantslast 30 patents

Information Patent Grant
17ß-hydroxysteroid dehydrogenase type 13 (HSD17B13) iRNA compositio...
- Patent number 12,359,201
- Issue date Jul 15, 2025
- REGENERON PHARMACEUTICALS, INC.
- Gregory Hinkle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,344,839
- Issue date Jul 1, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher f...
- Patent number 12,338,439
- Issue date Jun 24, 2025
- Alnylam Pharmaceuticals, Inc.
- Akin Akinc
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Aptamer for sclerostin and use thereof
- Patent number 12,338,441
- Issue date Jun 24, 2025
- APTACURE THERAPEUTICS LIMITED
- Ge Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified nucleic acids, hybrid guide RNAS, and uses thereof
- Patent number 12,338,433
- Issue date Jun 24, 2025
- OHIO STATE INNOVATION FOUNDATION
- Yizhou Dong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for modulating gene expression using oligo...
- Patent number 12,319,914
- Issue date Jun 3, 2025
- Larry J. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides targeting frataxin and related methods
- Patent number 12,312,585
- Issue date May 27, 2025
- UNIVERSITY OF MASSACHUSETTS
- Feng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Treatment of MST1 related diseases and disorders
- Patent number 12,312,586
- Issue date May 27, 2025
- EMPIRICO INC.
- Omri Gottesman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,297,429
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
O-methyl rich fully stabilized oligonucleotides
- Patent number 12,297,430
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
- Patent number 12,291,709
- Issue date May 6, 2025
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified RNAi agents
- Patent number 12,290,573
- Issue date May 6, 2025
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing prion expression
- Patent number 12,281,305
- Issue date Apr 22, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Muscle targeting complexes and uses thereof for treating myotonic d...
- Patent number 12,280,122
- Issue date Apr 22, 2025
- Dyne Therapeutics, Inc.
- Romesh R. Subramanian
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid, composition and conjugate containing same, preparatio...
- Patent number 12,274,752
- Issue date Apr 15, 2025
- Suzhou Ribo Life Science Co., Ltd.
- Hongyan Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conjugated antisense compounds and their use
- Patent number 12,275,940
- Issue date Apr 15, 2025
- Ionis Pharmaceuticals, Inc.
- Michael Oestergaard
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides for inducing paternal UBE3A expression
- Patent number 12,259,380
- Issue date Mar 25, 2025
- HOFFMANN-LA ROCHE INC.
- Veronica Costa
- G01 - MEASURING TESTING
Information Patent Grant
Modified oligonucleotides
- Patent number 12,258,563
- Issue date Mar 25, 2025
- EMPIRICO INC.
- Darren H. Wakefield
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting LPA expression
- Patent number 12,252,691
- Issue date Mar 18, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Tuning cascade assay kinetics via molecular design
- Patent number 12,247,205
- Issue date Mar 11, 2025
- VedaBio, Inc.
- Ashish Pandey
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
FN3 domain-siRNA conjugates and uses thereof
- Patent number 12,239,710
- Issue date Mar 4, 2025
- ARO BIOTHERAPEUTICS COMPANY
- Swapnil Kulkarni
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified messenger RNA comprising functional RNA elements
- Patent number 12,241,063
- Issue date Mar 4, 2025
- ModernaTX, Inc.
- Melissa J. Moore
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating APOC3 expression
- Patent number 12,234,456
- Issue date Feb 25, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for modulating SCN2A
- Patent number 12,227,746
- Issue date Feb 18, 2025
- Ionis Pharmaceuticals, Inc.
- Paymaan Jafar-nejad
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CCR7 aptamers and uses thereof
- Patent number 12,194,056
- Issue date Jan 14, 2025
- City of Hope
- John J. Rossi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
- Patent number 12,188,017
- Issue date Jan 7, 2025
- Arrowhead Pharmaceuticals, Inc.
- Christine I Wooddell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antisense oligonucleotides for the treatment of Stargardt disease
- Patent number 12,180,471
- Issue date Dec 31, 2024
- ProQR Therapeutics II B.V.
- Aliye Seda Yilmaz-Elis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dynamic pharmacokinetic-modifying anchors
- Patent number 12,180,477
- Issue date Dec 31, 2024
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for improving strand biased
- Patent number 12,173,287
- Issue date Dec 24, 2024
- Alnylam Pharmaceuticals, Inc.
- Rubina G. Parmar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-editing oligonucleotides and uses thereof
- Patent number 12,173,285
- Issue date Dec 24, 2024
- Korro Bio, Inc.
- Andrew W. Fraley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
Methods For The Treatment Of ANGPTL3-Related Diseases And Disorders
- Publication number 20250230439
- Publication date Jul 17, 2025
- Arrowhead Pharmaceuticals, Inc.
- Javier San Martin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INSULIN RECEPTOR-BINDING APTAMER DIMER AND USE THEREOF
- Publication number 20250223600
- Publication date Jul 10, 2025
- POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
- Sung Ho RYU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYF2 ANTISENSE OLIGONUCLEOTIDES
- Publication number 20250223591
- Publication date Jul 10, 2025
- AcuraStem Incorported
- Emily Elizabeth LEE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES
- Publication number 20250223588
- Publication date Jul 10, 2025
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED RNAi AGENTS
- Publication number 20250213720
- Publication date Jul 3, 2025
- Kallanthottathil G. RAJEEV
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TUNING CASCADE ASSAY KINETICS VIA MOLECULAR DESIGN
- Publication number 20250215428
- Publication date Jul 3, 2025
- VedaBio, Inc.
- Jacob Berger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDE AND COMP...
- Publication number 20250207137
- Publication date Jun 26, 2025
- Bioneer Corporation
- Tae-Rim KIM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...
- Publication number 20250207138
- Publication date Jun 26, 2025
- Amgen Inc.
- Bryan MEADE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kina...
- Publication number 20250207139
- Publication date Jun 26, 2025
- Arrowhead Pharmaceuticals, Inc.
- Michelle Ngai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF FOR EXON SKIPPING
- Publication number 20250197857
- Publication date Jun 19, 2025
- WAVE LIFE SCIENCES LTD.
- Xiao Shelley Hu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SIRNA TARGETING ANGIOTENSINOGEN AND PHARMACEUTICAL USE OF SIRNA
- Publication number 20250197853
- Publication date Jun 19, 2025
- Tuojie Biotech (Shanghai) Co., Ltd.
- Xiaoyan LIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi Agents of Modulating PLP1
- Publication number 20250197858
- Publication date Jun 19, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION OF ALPHA-1...
- Publication number 20250197861
- Publication date Jun 19, 2025
- Arrowhead Pharmaceuticals, Inc.
- Christine I. Wooddell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LNCRNA TRANSCRIPTS IN MELANOMAGENESIS
- Publication number 20250197864
- Publication date Jun 19, 2025
- The Regents of the University of California
- Susana Ortiz Urda
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (...
- Publication number 20250197859
- Publication date Jun 19, 2025
- EMPIRICO INC.
- Omri GOTTESMAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
siRNA SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR 2
- Publication number 20250188478
- Publication date Jun 12, 2025
- DAIICHI SANKYO COMPANY, LIMITED
- Makoto KOIZUMI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYNUCLEIC ACID MOLECULES FOR INHIBITING EXPRESSION OF LP(A), PHAR...
- Publication number 20250188464
- Publication date Jun 12, 2025
- Sirius Therapeutics, Inc.
- Curt BRADSHAW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NONCOVALENTLY BRANCHED OLIGONUCLEOTIDE COMPOSITIONS
- Publication number 20250188471
- Publication date Jun 12, 2025
- Atalanta Therapeutics, Inc.
- Matthew HASSLER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20250188475
- Publication date Jun 12, 2025
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES
- Publication number 20250188453
- Publication date Jun 12, 2025
- Switch Therapeutics Inc.
- Si-ping Han
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Antisense Nucleic Acids
- Publication number 20250188459
- Publication date Jun 12, 2025
- NIPPON SHINYAKU CO., LTD.
- Naoki Watanabe
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYNUCLEIC ACID MOLECULES TARGETING APOC3 AND USES THEREOF
- Publication number 20250188465
- Publication date Jun 12, 2025
- Sirius Therapeutics, Inc.
- Curt BRADSHAW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods and Compositions for Treatment of Polycystic Kidney Disease
- Publication number 20250188466
- Publication date Jun 12, 2025
- REGULUS THERAPEUTICS INC.
- Denis Drygin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SARM1 RNA INTERFERENCE AGENTS
- Publication number 20250188472
- Publication date Jun 12, 2025
- Eli Lilly and Company
- Nicholas Alan BABB
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HETERONUCLEIC ACID INCLUDING 2'-MODIFIED NUCLEOSIDE
- Publication number 20250179486
- Publication date Jun 5, 2025
- NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
- Takanori Yokota
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF EXPANDED REPEAT-ASSOC...
- Publication number 20250177431
- Publication date Jun 5, 2025
- University of Massachusetts
- Joel D. Richter
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS OF MODIFIED TREMS AND USES THEREOF
- Publication number 20250179492
- Publication date Jun 5, 2025
- Flagship Pioneering Innovations VI, LLC.
- Theonie Anastassiadis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE
- Publication number 20250171785
- Publication date May 29, 2025
- Alnylam Pharmaceuticals, Inc.
- Pamela Tan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Microtubule Associated Protein Tau (MAPT) iRNA Agent Compositions a...
- Publication number 20250171777
- Publication date May 29, 2025
- Alnylam Pharmaceuticals, Inc.
- JEFFREY ZUBER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED
- Publication number 20250163417
- Publication date May 22, 2025
- ALNYLAM PHARMACEUTICALS,INC.
- Rubina G. PARMAR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

2'-R Modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

17ß-hydroxysteroid dehydrogenase type 13 (HSD17B13) iRNA compositio...

Dual-acting siRNA based modulation of C9orf72

Factor XII (hageman factor) (F12), kallikrein B, plasma (fletcher f...

Aptamer for sclerostin and use thereof

Modified nucleic acids, hybrid guide RNAS, and uses thereof

Methods and compositions for modulating gene expression using oligo...

Oligonucleotides targeting frataxin and related methods

Treatment of MST1 related diseases and disorders

Dual-acting siRNA based modulation of C9orf72

O-methyl rich fully stabilized oligonucleotides

Compositions and methods for modulating apolipoprotein (a) expression

Modified RNAi agents

Compounds and methods for reducing prion expression

Muscle targeting complexes and uses thereof for treating myotonic d...

Nucleic acid, composition and conjugate containing same, preparatio...

Conjugated antisense compounds and their use

Oligonucleotides for inducing paternal UBE3A expression

Modified oligonucleotides

Compositions and methods for inhibiting LPA expression

Tuning cascade assay kinetics via molecular design

FN3 domain-siRNA conjugates and uses thereof

Modified messenger RNA comprising functional RNA elements

Compositions and methods for modulating APOC3 expression

Compounds and methods for modulating SCN2A

CCR7 aptamers and uses thereof

Compositions and methods for inhibiting gene expression of alpha-1...

Antisense oligonucleotides for the treatment of Stargardt disease

Dynamic pharmacokinetic-modifying anchors

Compositions and methods for improving strand biased

RNA-editing oligonucleotides and uses thereof

Patents Applicationslast 30 patents

Methods For The Treatment Of ANGPTL3-Related Diseases And Disorders

INSULIN RECEPTOR-BINDING APTAMER DIMER AND USE THEREOF

SYF2 ANTISENSE OLIGONUCLEOTIDES

OLIGONUCLEOTIDES WITH 2'-DEOXY-2'-F-2'-C-METHYL NUCLEOTIDES

MODIFIED RNAi AGENTS

TUNING CASCADE ASSAY KINETICS VIA MOLECULAR DESIGN

AMPHIREGULIN GENE-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDE AND COMP...

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...

RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kina...

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF FOR EXON SKIPPING

SIRNA TARGETING ANGIOTENSINOGEN AND PHARMACEUTICAL USE OF SIRNA

RNAi Agents of Modulating PLP1

COMPOSITIONS AND METHODS FOR INHIBITING GENE EXPRESSION OF ALPHA-1...

LNCRNA TRANSCRIPTS IN MELANOMAGENESIS

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (...

siRNA SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR 2

POLYNUCLEIC ACID MOLECULES FOR INHIBITING EXPRESSION OF LP(A), PHAR...

NONCOVALENTLY BRANCHED OLIGONUCLEOTIDE COMPOSITIONS

KETOHEXOKINASE (KHK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

CONDITIONALLY ACTIVATABLE NUCLEIC ACID COMPLEXES

Antisense Nucleic Acids

POLYNUCLEIC ACID MOLECULES TARGETING APOC3 AND USES THEREOF

Methods and Compositions for Treatment of Polycystic Kidney Disease

SARM1 RNA INTERFERENCE AGENTS

HETERONUCLEIC ACID INCLUDING 2'-MODIFIED NUCLEOSIDE

COMPOSITIONS AND METHODS FOR THE TREATMENT OF EXPANDED REPEAT-ASSOC...

COMPOSITIONS OF MODIFIED TREMS AND USES THEREOF

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE

Microtubule Associated Protein Tau (MAPT) iRNA Agent Compositions a...

COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED