2'-R Modification

Industry

CPC
C12N2310/322

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

Current Industry

C12N2310/3222'-R Modification

Industries

Patents Grantslast 30 patents

Information Patent Grant
Methods and compositions for modulating gene expression using oligo...
- Patent number 12,319,914
- Issue date Jun 3, 2025
- Larry J. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides targeting frataxin and related methods
- Patent number 12,312,585
- Issue date May 27, 2025
- UNIVERSITY OF MASSACHUSETTS
- Feng Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Treatment of MST1 related diseases and disorders
- Patent number 12,312,586
- Issue date May 27, 2025
- EMPIRICO INC.
- Omri Gottesman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dual-acting siRNA based modulation of C9orf72
- Patent number 12,297,429
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
O-methyl rich fully stabilized oligonucleotides
- Patent number 12,297,430
- Issue date May 13, 2025
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
- Patent number 12,291,709
- Issue date May 6, 2025
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified RNAi agents
- Patent number 12,290,573
- Issue date May 6, 2025
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing prion expression
- Patent number 12,281,305
- Issue date Apr 22, 2025
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Muscle targeting complexes and uses thereof for treating myotonic d...
- Patent number 12,280,122
- Issue date Apr 22, 2025
- Dyne Therapeutics, Inc.
- Romesh R. Subramanian
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid, composition and conjugate containing same, preparatio...
- Patent number 12,274,752
- Issue date Apr 15, 2025
- Suzhou Ribo Life Science Co., Ltd.
- Hongyan Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conjugated antisense compounds and their use
- Patent number 12,275,940
- Issue date Apr 15, 2025
- Ionis Pharmaceuticals, Inc.
- Michael Oestergaard
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides for inducing paternal UBE3A expression
- Patent number 12,259,380
- Issue date Mar 25, 2025
- HOFFMANN-LA ROCHE INC.
- Veronica Costa
- G01 - MEASURING TESTING
Information Patent Grant
Modified oligonucleotides
- Patent number 12,258,563
- Issue date Mar 25, 2025
- EMPIRICO INC.
- Darren H. Wakefield
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting LPA expression
- Patent number 12,252,691
- Issue date Mar 18, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Tuning cascade assay kinetics via molecular design
- Patent number 12,247,205
- Issue date Mar 11, 2025
- VedaBio, Inc.
- Ashish Pandey
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
FN3 domain-siRNA conjugates and uses thereof
- Patent number 12,239,710
- Issue date Mar 4, 2025
- ARO BIOTHERAPEUTICS COMPANY
- Swapnil Kulkarni
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified messenger RNA comprising functional RNA elements
- Patent number 12,241,063
- Issue date Mar 4, 2025
- ModernaTX, Inc.
- Melissa J. Moore
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating APOC3 expression
- Patent number 12,234,456
- Issue date Feb 25, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for modulating SCN2A
- Patent number 12,227,746
- Issue date Feb 18, 2025
- Ionis Pharmaceuticals, Inc.
- Paymaan Jafar-nejad
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CCR7 aptamers and uses thereof
- Patent number 12,194,056
- Issue date Jan 14, 2025
- City of Hope
- John J. Rossi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
- Patent number 12,188,017
- Issue date Jan 7, 2025
- Arrowhead Pharmaceuticals, Inc.
- Christine I Wooddell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antisense oligonucleotides for the treatment of Stargardt disease
- Patent number 12,180,471
- Issue date Dec 31, 2024
- ProQR Therapeutics II B.V.
- Aliye Seda Yilmaz-Elis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dynamic pharmacokinetic-modifying anchors
- Patent number 12,180,477
- Issue date Dec 31, 2024
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for improving strand biased
- Patent number 12,173,287
- Issue date Dec 24, 2024
- Alnylam Pharmaceuticals, Inc.
- Rubina G. Parmar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA-editing oligonucleotides and uses thereof
- Patent number 12,173,285
- Issue date Dec 24, 2024
- Korro Bio, Inc.
- Andrew W. Fraley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
- Patent number 12,163,132
- Issue date Dec 10, 2024
- Children's National Medical Center
- Yi-Wen Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for the treatment of expanded repeat-assoc...
- Patent number 12,161,658
- Issue date Dec 10, 2024
- UNIVERSITY OF MASSACHUSETTS
- Joel D. Richter
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
- Patent number 12,163,129
- Issue date Dec 10, 2024
- University of Massachusetts
- Robert H. Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bi specific aptamer
- Patent number 12,138,279
- Issue date Nov 12, 2024
- City of Hope
- John J. Rossi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified short interfering nucleic acid (siNA) molecules and uses t...
- Patent number 12,129,469
- Issue date Oct 29, 2024
- Aligos Therapeutics, Inc.
- Leonid Beigelman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
HETERONUCLEIC ACID INCLUDING 2'-MODIFIED NUCLEOSIDE
- Publication number 20250179486
- Publication date Jun 5, 2025
- NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
- Takanori Yokota
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS OF MODIFIED TREMS AND USES THEREOF
- Publication number 20250179492
- Publication date Jun 5, 2025
- Flagship Pioneering Innovations VI, LLC.
- Theonie Anastassiadis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF EXPANDED REPEAT-ASSOC...
- Publication number 20250177431
- Publication date Jun 5, 2025
- University of Massachusetts
- Joel D. Richter
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE
- Publication number 20250171785
- Publication date May 29, 2025
- Alnylam Pharmaceuticals, Inc.
- Pamela Tan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Microtubule Associated Protein Tau (MAPT) iRNA Agent Compositions a...
- Publication number 20250171777
- Publication date May 29, 2025
- Alnylam Pharmaceuticals, Inc.
- JEFFREY ZUBER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED
- Publication number 20250163417
- Publication date May 22, 2025
- ALNYLAM PHARMACEUTICALS,INC.
- Rubina G. PARMAR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...
- Publication number 20250154512
- Publication date May 15, 2025
- Amgen Inc.
- Ingrid RULIFSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Antisense Nucleic Acids
- Publication number 20250145997
- Publication date May 8, 2025
- Nippon Shinyaku co., Ltd.
- Tatsushi Wakayama
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES TARGETING RNA BINDING PROTEIN SITES
- Publication number 20250145996
- Publication date May 8, 2025
- HOFFMANN-LA ROCHE INC.
- Jessica Marine Aurore BASTIEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF
- Publication number 20250135036
- Publication date May 1, 2025
- WAVE LIFE SCIENCES LTD.
- Christopher Michael Acker
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
iRNA Compositions and Methods for Silencing ANGPTL4
- Publication number 20250136978
- Publication date May 1, 2025
- Alnylam Pharmaceuticals, Inc.
- JEFFREY ZUBER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi OLIGONUCLEOTIDE CONJUGATES
- Publication number 20250122500
- Publication date Apr 17, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMBINATIONS WITH MODULATORS OF PNPLA3 EXPRESSION
- Publication number 20250122504
- Publication date Apr 17, 2025
- AstraZeneca AB
- Daniel LINDÉN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUNDS FOR INHIBITING AMANZI
- Publication number 20250115909
- Publication date Apr 10, 2025
- LEMBA BV
- Ezio Fok
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION
- Publication number 20250116656
- Publication date Apr 10, 2025
- HOFFMANN-LA ROCHE INC.
- Veronica COSTA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20250115915
- Publication date Apr 10, 2025
- ADARx Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SNCA-TARGETING SIRNA COMPOSITIONS FOR TREATING SNCA-ASSOCIATED DISEASE
- Publication number 20250115911
- Publication date Apr 10, 2025
- Alnylam Pharmaceuticals, Inc.
- Lan Thi Hoang Dang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IONIZABLE LIPIDS, LIPID NANOPARTICLES, AND USES THEREOF
- Publication number 20250099393
- Publication date Mar 27, 2025
- Verily Life Sciences LLC
- Zhan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHEMICALLY MODIFIED ANTISENSE OLIGONUCLEOTIDES (ASOS) AND COMPOSITI...
- Publication number 20250101418
- Publication date Mar 27, 2025
- Eberhard-Karls-Universitat Tubingen
- Thorsten Stafforst
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANC...
- Publication number 20250101422
- Publication date Mar 27, 2025
- Larry J. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED siRNA FOR SELECTIVELY INHIBITING EXPRESSION OF MUTANT FUS
- Publication number 20250101420
- Publication date Mar 27, 2025
- OHARA PHARMACEUTICAL CO., LTD.
- Naoki Morita
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATMENT OF TRANSTHYRETIN AMYLOIDOSIS
- Publication number 20250101416
- Publication date Mar 27, 2025
- ACCUREDIT THERAPEUTICS (SUZHOU) CO., LTD.
- Fuxin SHI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ADVANCED RNA TARGETING (ARNATAR)
- Publication number 20250101423
- Publication date Mar 27, 2025
- Arnatar Therapeutics, Inc
- Xuehai Liang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DEGRADATION OF RNA BY THE LYSOSOMAL PATHWAY
- Publication number 20250101432
- Publication date Mar 27, 2025
- University of Massachusetts
- Micah Belew
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING KETOHEXOKINASE (KHK)
- Publication number 20250092403
- Publication date Mar 20, 2025
- Dicerna Pharmaceuticals, Inc.
- Bob Dale BROWN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GUIDE RNA WITH CHEMICAL MODIFICATIONS
- Publication number 20250092389
- Publication date Mar 20, 2025
- Agilent Technologies, Inc.
- Daniel E. Ryan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HEPARIN SULFATE BIOSYNTHESIS PATHWAY ENZYME IRNA AGENT COMPOSITIONS...
- Publication number 20250084417
- Publication date Mar 13, 2025
- Alnylam Pharmaceuticals, Inc.
- Mangala Meenakshi Soundarapandian
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20250073256
- Publication date Mar 6, 2025
- ADARx Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAi Agents for Inhibiting Expression of Inhibin Subunit Beta E (IN...
- Publication number 20250075214
- Publication date Mar 6, 2025
- Arrowhead Pharmaceuticals, Inc.
- Michelle Ngai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAS FOR COMPLEMENT INHIBITION
- Publication number 20250075209
- Publication date Mar 6, 2025
- Apellis Pharmaceuticals, Inc.
- Jasmin Gegner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

2'-R Modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Methods and compositions for modulating gene expression using oligo...

Oligonucleotides targeting frataxin and related methods

Treatment of MST1 related diseases and disorders

Dual-acting siRNA based modulation of C9orf72

O-methyl rich fully stabilized oligonucleotides

Compositions and methods for modulating apolipoprotein (a) expression

Modified RNAi agents

Compounds and methods for reducing prion expression

Muscle targeting complexes and uses thereof for treating myotonic d...

Nucleic acid, composition and conjugate containing same, preparatio...

Conjugated antisense compounds and their use

Oligonucleotides for inducing paternal UBE3A expression

Modified oligonucleotides

Compositions and methods for inhibiting LPA expression

Tuning cascade assay kinetics via molecular design

FN3 domain-siRNA conjugates and uses thereof

Modified messenger RNA comprising functional RNA elements

Compositions and methods for modulating APOC3 expression

Compounds and methods for modulating SCN2A

CCR7 aptamers and uses thereof

Compositions and methods for inhibiting gene expression of alpha-1...

Antisense oligonucleotides for the treatment of Stargardt disease

Dynamic pharmacokinetic-modifying anchors

Compositions and methods for improving strand biased

RNA-editing oligonucleotides and uses thereof

Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...

Compositions and methods for the treatment of expanded repeat-assoc...

Antisense oligonucleotides to restore dysferlin protein expression...

Bi specific aptamer

Modified short interfering nucleic acid (siNA) molecules and uses t...

Patents Applicationslast 30 patents

HETERONUCLEIC ACID INCLUDING 2'-MODIFIED NUCLEOSIDE

COMPOSITIONS OF MODIFIED TREMS AND USES THEREOF

COMPOSITIONS AND METHODS FOR THE TREATMENT OF EXPANDED REPEAT-ASSOC...

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE

Microtubule Associated Protein Tau (MAPT) iRNA Agent Compositions a...

COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED

RNAI CONSTRUCTS FOR INHIBITING PNPLA3 EXPRESSION AND METHODS OF USE...

Antisense Nucleic Acids

OLIGONUCLEOTIDES TARGETING RNA BINDING PROTEIN SITES

COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF

iRNA Compositions and Methods for Silencing ANGPTL4

RNAi OLIGONUCLEOTIDE CONJUGATES

COMBINATIONS WITH MODULATORS OF PNPLA3 EXPRESSION

COMPOUNDS FOR INHIBITING AMANZI

OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION

PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF

SNCA-TARGETING SIRNA COMPOSITIONS FOR TREATING SNCA-ASSOCIATED DISEASE

IONIZABLE LIPIDS, LIPID NANOPARTICLES, AND USES THEREOF

CHEMICALLY MODIFIED ANTISENSE OLIGONUCLEOTIDES (ASOS) AND COMPOSITI...

METHODS AND MODIFICATIONS THAT PRODUCE ssRNAi COMPOUNDS WITH ENHANC...

MODIFIED siRNA FOR SELECTIVELY INHIBITING EXPRESSION OF MUTANT FUS

COMPOSITIONS AND METHODS FOR TREATMENT OF TRANSTHYRETIN AMYLOIDOSIS

ADVANCED RNA TARGETING (ARNATAR)

DEGRADATION OF RNA BY THE LYSOSOMAL PATHWAY

COMPOSITIONS AND METHODS FOR INHIBITING KETOHEXOKINASE (KHK)

GUIDE RNA WITH CHEMICAL MODIFICATIONS

HEPARIN SULFATE BIOSYNTHESIS PATHWAY ENZYME IRNA AGENT COMPOSITIONS...

PREKALLIKREIN-MODULATING COMPOSITIONS AND METHODS OF USE THEREOF

RNAi Agents for Inhibiting Expression of Inhibin Subunit Beta E (IN...

RNAS FOR COMPLEMENT INHIBITION