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Coagulation factor Xa (3.4.21.6)
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C12Y304/21006
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C12
Biochemistry
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C12Y304/00
Hydrolases acting on peptide bonds
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C12Y304/21006
Coagulation factor Xa (3.4.21.6)
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Patents Grants
last 30 patents
Information
Patent Grant
Antidotes to factor XA inhibitors
Patent number
12,195,774
Issue date
Jan 14, 2025
Alexion Pharmaceuticals, Inc.
Pamela B. Conley
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
12,083,170
Issue date
Sep 10, 2024
Academisch Ziekenhuis Leiden
Daniël Verhoef
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lyophilized formulations for factor XA antidote
Patent number
12,005,144
Issue date
Jun 11, 2024
Alexion Pharmaceuticals, Inc.
Phuong M. Nguyen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
11,839,646
Issue date
Dec 12, 2023
Alexion Pharmaceuticals, Inc.
Genmin Lu
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Extracellular histones as biomarkers for prognosis and molecular ta...
Patent number
11,458,187
Issue date
Oct 4, 2022
Oklahoma Medical Research Foundation
Charles T. Esmon
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
11,357,836
Issue date
Jun 14, 2022
Academisch Ziekenhuis Leiden
Daniël Verhoef
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
11,304,995
Issue date
Apr 19, 2022
Academisch Ziekenhuis Leiden
Daniël Verhoef
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chimeric clotting factors
Patent number
11,168,316
Issue date
Nov 9, 2021
Bioverativ Therapeutics, Inc.
Joe Salas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions of human prothrombin and activated factor X for improv...
Patent number
11,160,850
Issue date
Nov 2, 2021
Takeda Pharmaceutical Company Limited
Michael Dockal
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Clotting composition
Patent number
11,103,560
Issue date
Aug 31, 2021
Q-SERA PTY LTD.
Paul Masci
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
11,085,032
Issue date
Aug 10, 2021
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lyophilized formulations for factor Xa antidote
Patent number
11,028,382
Issue date
Jun 8, 2021
Alexion Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,954,503
Issue date
Mar 23, 2021
Alexion Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Clotting composition
Patent number
10,786,553
Issue date
Sep 29, 2020
Q-SERA PTY LTD.
Paul Masci
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Unit dose formulation of antidotes for factor Xa inhibitors and met...
Patent number
10,765,726
Issue date
Sep 8, 2020
Portola Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Tissue factor (TF)—targeted nanotherapy
Patent number
10,738,294
Issue date
Aug 11, 2020
Melina R. Kibbe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,675,335
Issue date
Jun 9, 2020
Portola Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
10,676,730
Issue date
Jun 9, 2020
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
10,655,119
Issue date
May 19, 2020
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Non-cytotoxic protein conjugates
Patent number
10,619,146
Issue date
Apr 14, 2020
Ipsen Bioinnovation Limited
Keith Foster
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for counteracting Factor Xa inhibition
Patent number
10,588,950
Issue date
Mar 17, 2020
Pfizer Inc.
Debra D. Pittman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method of manufacturing and purifying prothrombin complex concentra...
Patent number
10,583,179
Issue date
Mar 10, 2020
Kieu Hoang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
One component fibrin glue comprising zymogens
Patent number
10,555,991
Issue date
Feb 11, 2020
Omrix Biopharmaceuticals Ltd.
Yair Pilpel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
10,537,618
Issue date
Jan 21, 2020
Academisch Ziekenhuis Leiden
Daniël Verhoef
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Factor X mutants
Patent number
10,364,424
Issue date
Jul 30, 2019
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
Jean-Luc Plantier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Extracellular histones as biomarkers for prognosis and molecular ta...
Patent number
10,350,261
Issue date
Jul 16, 2019
Oklahoma Medical Research Foundation
Charles T. Esmon
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for universal determination of anticoagulant activity
Patent number
10,337,048
Issue date
Jul 2, 2019
Roche Diagnostics Operations, Inc.
Friedrich Ackermann
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Extracellular histones as biomarkers for prognosis and molecular ta...
Patent number
10,238,711
Issue date
Mar 26, 2019
Oklahoma Medical Research Foundation
Charles T. Esmon
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Chimeric clotting factors
Patent number
10,202,595
Issue date
Feb 12, 2019
Bioverativ Therapeutics Inc.
Joe Salas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,190,111
Issue date
Jan 29, 2019
Portola Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20240390467
Publication date
Nov 28, 2024
Academisch Ziekenhuis Leiden
Daniël VERHOEF
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20240189401
Publication date
Jun 13, 2024
Alexion Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS
Publication number
20240101973
Publication date
Mar 28, 2024
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20240082367
Publication date
Mar 14, 2024
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITOR
Publication number
20230383276
Publication date
Nov 30, 2023
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20230000957
Publication date
Jan 5, 2023
Alexion Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20220354792
Publication date
Nov 10, 2022
Alexion Pharmaceuticals, Inc.
Phuong M. Nguyen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20220288172
Publication date
Sep 15, 2022
Academisch Ziekenhuis Leiden
Daniël VERHOEF
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS
Publication number
20220228131
Publication date
Jul 21, 2022
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING ACTIVE VITAMIN K-DEPENDENT P...
Publication number
20220177856
Publication date
Jun 9, 2022
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHIMERIC CLOTTING FACTORS
Publication number
20220135959
Publication date
May 5, 2022
Bioverativ Therapeutics Inc.
Joe SALAS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR TREATING INTRACRANIAL HEMORRHAGE AND ASSESSING EFFICACY
Publication number
20220125894
Publication date
Apr 28, 2022
Alexion Pharmaceuticals, Inc.
Patrick Yue
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITOR
Publication number
20220098565
Publication date
Mar 31, 2022
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR XA DERIVA...
Publication number
20210379163
Publication date
Dec 9, 2021
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20210340515
Publication date
Nov 4, 2021
Alexion Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING ACTIVE VITAMIN K-DEPENDENT P...
Publication number
20210332333
Publication date
Oct 28, 2021
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FX ACTIVATION PROCESS AND ITS USE IN THE PREPARATION OF A FXA COMPO...
Publication number
20210290738
Publication date
Sep 23, 2021
Octapharma AG
Juergen Roland ROEMISCH
C07 - ORGANIC CHEMISTRY
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20210284986
Publication date
Sep 16, 2021
Alexion Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS
Publication number
20210130795
Publication date
May 6, 2021
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20210085762
Publication date
Mar 25, 2021
Portola Pharmaceuticals, Inc.
UMA SINHA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CLOTTING COMPOSITION
Publication number
20210000925
Publication date
Jan 7, 2021
Q-Sera PTY LTD
Paul MASCI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR COUNTERACTING FACTOR XA INHIBITION
Publication number
20210000930
Publication date
Jan 7, 2021
Pfizer Inc.
Debra D. Pittman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MUTATED FACTOR X POLYPEPTIDES AND USES THEREOF FOR THE TREATMENT OF...
Publication number
20200299666
Publication date
Sep 24, 2020
Inserm (institut National de la Sante et de la Recherche Medicale)
Olivier CHRISTOPHE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20200299667
Publication date
Sep 24, 2020
Portola Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20200299668
Publication date
Sep 24, 2020
Portola Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20200276280
Publication date
Sep 3, 2020
Portola Pharmaceuticals, Inc.
GENMIN LU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS
Publication number
20200263148
Publication date
Aug 20, 2020
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MUTATED FACTOR X POLYPEPTIDES AND USES THEREOF FOR THE TREATMENT OF...
Publication number
20200248162
Publication date
Aug 6, 2020
Inserm (institut National de la Sante et de la Recherche Medicale)
Olivier CHRISTOPHE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR PRODUCING ACTIVE VITAMIN K-DEPENDENT P...
Publication number
20200224177
Publication date
Jul 16, 2020
The University of North Carolina at Chapel Hill
Darrel W. Stafford
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20200138917
Publication date
May 7, 2020
Academisch Ziekenhuis Leiden
Daniël VERHOEF
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE