containing a nuclear localisation signal

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2319/00Fusion polypeptide

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C07K2319/09containing a nuclear localisation signal

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Patents Grantslast 30 patents

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containing a nuclear localisation signal

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Delivery, use and therapeutic applications of the CRISPR-Cas system...

Engineered cascade components and cascade complexes

Modulators of CAS9 polypeptides and methods of use thereof

Using nucleosome interacting protein domains to enhance targeted ge...

RNA-targeting system

Fusion proteins for improved precision in base editing

Proximity-dependent biotinylation and uses thereof

Transcription factor-mediated promotion of direct somatic embryogen...

Engineering and optimization of systems, methods, enzymes and guide...

Cell penetrating peptides that inhibit IRF5 nuclear localization

Base editors and uses thereof

Fusion protein and use thereof in base editing

Excision of retroviral nucleic acid sequences

CRISPR enzyme mutations reducing off-target effects

DNA vectors, transposons and transposases for eukaryotic genome mod...

Base editing tool and use thereof

Base editing of ANGPTL3 and methods of using same for treatment of...

Compositions and methods for targeting nuclear import shuttles and...

Using nucleosome interacting protein domains to enhance targeted ge...

Telomerase encoding DNA vaccine

DNA vectors, transposons and transposases for eukaryotic genome mod...

Evolved Cas9 proteins for gene editing

Transfection complexes and methods of using the same

Base editing of PCSK9 and methods of using same for treatment of di...

Flp-TAL recombinases

Compositions and methods for diagnosing and/or treating kidney injury

Compositions and methods for treating hemoglobinopathies

Mutant MYC fusion polypeptides and uses thereof

Methods for treating myelin associated diseases and mitochondria as...

Multi-level specific targeting of cancer cells

Patents Applicationslast 30 patents

EVOLVED CAS14A1 VARIANTS, COMPOSITIONS, AND METHODS OF MAKING AND U...

MODIFIED REGULATORY T CELLS AND METHODS OF USING THE SAME

MITOCHONDRIAL BASE EDITORS AND METHODS FOR EDITING MITOCHONDRIAL DNA

EVOLVED CAS9 PROTEINS FOR GENE EDITING

COMPOSITIONS AND METHODS FOR CAPPING RNAS

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

COMPOSITIONS AND METHODS FOR TARGETED MODIFICATION OF MSH3

SYNTHETIC TRANSCRIPTION FACTORS

ELECTROPORATION ENHANCERS FOR CRISPR-CAS SYSTEMS

BASE EDITORS AND USES THEREOF

REGULATED SYNTHETIC GENE ACTIVATION SYSTEMS

Engineered High Activity Omni-79 Nuclease Variants

DNA VECTORS, TRANSPOSONS AND TRANSPOSASES FOR EUKARYOTIC GENOME MOD...

COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY

NOVEL RNA BASE EDITING COMPOSITIONS, SYSTEMS, METHODS AND USES THEREOF

ADENOVIRUS DELIVERY SYSTEM FOR CANCER TREATMENT

BASE EDITORS, COMPOSITIONS, AND METHODS FOR MODIFYING THE MITOCHOND...

MODULATION OF THE CRISPR ROADBLOCK

CLASS II, TYPE V CRISPR SYSTEMS

EXPRESSION SYSTEM FOR CONSTITUTIVE OR CUMATE-INDUCIBLE EXPRESSION I...

COMPOSITIONS AND METHODS FOR IMPROVED GENOME EDITING WITH NME2CAS9...

METHODS AND COMPOSITIONS FOR GENOME EDITING

INTEGRASES, LANDING PAD ARCHITECTURES, AND ENGINEERED CELLS COMPRIS...

ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS

ENHANCED PROGRAMMABLE ADDITION VIA SITE-SPECIFIC TARGETING ELEMENTS...

BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...

TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME

METHODS AND COMPOSITIONS TO SPREAD PROTEIN CARGOES ACROSS MULTI-NUC...

COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS