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last 30 patents
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CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
12,365,887
Issue date
Jul 22, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modifying a target nucleic acid
Patent number
12,359,179
Issue date
Jul 15, 2025
The Regents of the University of California
Alexander Marson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Conjugates enhancing total cellular accumulation
Patent number
12,350,346
Issue date
Jul 8, 2025
DEFENCE THERAPEUTICS INC.
Simon Beaudoin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Nucleobase editors and uses thereof
Patent number
12,344,869
Issue date
Jul 1, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Cell membrane penetrating conjugates for gene editing
Patent number
12,331,310
Issue date
Jun 17, 2025
CYGENICA LIMITED
Nusrat Sanghamitra
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Methods and compositions for genomic integration
Patent number
12,319,925
Issue date
Jun 3, 2025
Myeloid Therapeutics, Inc.
Daniel Getts
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
12,312,614
Issue date
May 27, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
12,312,616
Issue date
May 27, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Disease treatment drug based on mesenchymal-stem-cell mobilization
Patent number
12,304,933
Issue date
May 20, 2025
STEMRIM INC.
Katsuto Tamai
C07 - ORGANIC CHEMISTRY
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Nuclear localization signals, compositions formed therefrom, and me...
Patent number
12,304,970
Issue date
May 20, 2025
Yale University
James E. Hansen
C07 - ORGANIC CHEMISTRY
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Methods and compositions for reducing the immunogenicity of chimeri...
Patent number
12,297,243
Issue date
May 13, 2025
Cell Design Labs, Inc.
Peter Emtage
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Rationally-designed synthetic peptide shuttle agents for delivering...
Patent number
12,286,632
Issue date
Apr 29, 2025
Feldan Bio Inc.
Thomas Del'Guidice
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Methods for increasing efficiency of nuclease-induced homology-dire...
Patent number
12,286,641
Issue date
Apr 29, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Genetically engineered cells
Patent number
12,275,966
Issue date
Apr 15, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Variant type V CRISPR/Cas effector polypeptides and methods of use...
Patent number
12,275,964
Issue date
Apr 15, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Delivery, use and therapeutic applications of the CRISPR-Cas system...
Patent number
12,251,450
Issue date
Mar 18, 2025
The Broad Institute, Inc.
Sangeeta Bhatia
G06 - COMPUTING CALCULATING COUNTING
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Engineered cascade components and cascade complexes
Patent number
12,227,776
Issue date
Feb 18, 2025
Caribou Biosciences, Inc.
Peter Sean Cameron
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Modulators of CAS9 polypeptides and methods of use thereof
Patent number
12,227,547
Issue date
Feb 18, 2025
The Regents of the University of California
Jennifer A Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Using nucleosome interacting protein domains to enhance targeted ge...
Patent number
12,221,606
Issue date
Feb 11, 2025
Sigma-Aldrich Co. LLC
Fuqiang Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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RNA-targeting system
Patent number
12,215,326
Issue date
Feb 4, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Fusion proteins for improved precision in base editing
Patent number
12,203,077
Issue date
Jan 21, 2025
ShanghaiTech University
Jia Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Proximity-dependent biotinylation and uses thereof
Patent number
12,188,059
Issue date
Jan 7, 2025
The Broad Institute, Inc.
Steven A. Carr
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Transcription factor-mediated promotion of direct somatic embryogen...
Patent number
12,188,032
Issue date
Jan 7, 2025
PERPETUUM CROPSCIENCE BV
Jeroen Hofenk
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Engineering and optimization of systems, methods, enzymes and guide...
Patent number
12,168,789
Issue date
Dec 17, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Cell penetrating peptides that inhibit IRF5 nuclear localization
Patent number
12,162,915
Issue date
Dec 10, 2024
Rutgers, The State University of New Jersey
Betsy J. Barnes
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Base editors and uses thereof
Patent number
12,157,760
Issue date
Dec 3, 2024
The Broad Institute, Inc.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Fusion protein and use thereof in base editing
Patent number
12,134,771
Issue date
Nov 5, 2024
ShanghaiTech University
Yajing Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Excision of retroviral nucleic acid sequences
Patent number
12,122,997
Issue date
Oct 22, 2024
Temple University - of the Commonwealth System of Higher Education
Kamel Khalili
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
CRISPR enzyme mutations reducing off-target effects
Patent number
12,123,032
Issue date
Oct 22, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
DNA vectors, transposons and transposases for eukaryotic genome mod...
Patent number
12,122,995
Issue date
Oct 22, 2024
DNA TWOPOINTO INC.
Jeremy Minshull
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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last 30 patents
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Patent Application
CRISPR/CAS9-BASED FUSION PROTEINS FOR MODULATING GENE EXPRESSION AN...
Publication number
20250236854
Publication date
Jul 24, 2025
Glaxosmithkline Intellectual Property Development Limited GSK Medicines Rese...
Syandan Chakraborty
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPR...
Publication number
20250236847
Publication date
Jul 24, 2025
nChroma Bio, Inc.
Aron Brandon Jaffe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
ENGINEERING SUICIDE GENE APPROACHES TO IMPROVE CHEMOTHERAPEUTIC RES...
Publication number
20250228978
Publication date
Jul 17, 2025
University of Virginia Patent Foundation
Matthew J. Lazzara
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
Publication number
20250230424
Publication date
Jul 17, 2025
Caribou Biosciences, Inc.
Stan Johan Josef Brouns
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
Publication number
20250223578
Publication date
Jul 10, 2025
Caribou Biosciences, Inc.
Stan Johan Josef Brouns
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR EFFICIENT IN VIVO DELIVERY
Publication number
20250223584
Publication date
Jul 10, 2025
THE BROAD INSTITUTE, INC.
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
OPTIMIZED CAS PROTEIN AND USE THEREOF
Publication number
20250223576
Publication date
Jul 10, 2025
SHANDONG SHUNFENG BIOTECHNOLOGY CO.LTD.
Zhiqiang DUAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
GUIDE NUCLEIC ACID TARGETING MECP2 AND USES THEREOF
Publication number
20250205366
Publication date
Jun 26, 2025
Huidagene Therapeutics (Singapore) Pte. Ltd.
Xing Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TARGETED DELIVERY OF ARMMS
Publication number
20250205357
Publication date
Jun 26, 2025
President and Fellows of Harvard College
Quan Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
FUSION PROTEINS COMPRISING AN E2 UBIQUITIN OR UBIQUITIN-LIKE CONJUG...
Publication number
20250197819
Publication date
Jun 19, 2025
MEDIMMUNE LIMITED
SANDRINE LEGG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
RNA TARGETING COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250197824
Publication date
Jun 19, 2025
University of Rochester
Tatsuaki KUROSAKI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR EPIGENETIC EDITING
Publication number
20250197818
Publication date
Jun 19, 2025
nChroma Bio, Inc.
Ari Friedland
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
NOVEL CAS EFFECTOR PROTEINS, GENE EDITING SYSTEMS, AND USES THEREOF
Publication number
20250197827
Publication date
Jun 19, 2025
GUANGZHOU REFORGENE MEDICINE CO., LTD.
Junbin LIANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
THERAPEUTIC NUCLEIC ACIDS, PEPTIDES AND USES I
Publication number
20250188137
Publication date
Jun 12, 2025
Imperial College Innovations Limited
Mark ISALAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
CELL PENETRATING PEPTIDES THAT INHIBIT IRF5 NUCLEAR LOCALIZATION
Publication number
20250188138
Publication date
Jun 12, 2025
Rutgers, The State University of New Jersey
Betsy J. Barnes
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
COMPOSITIONS AND METHODS FOR MODULATING ALPHA-SYNUCLEIN EXPRESSION
Publication number
20250177568
Publication date
Jun 5, 2025
The Board of Trustees of the Leland Stanford Junior University
C. Alejandra Morato Torres
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
CRISPR ENZYME MUTATIONS REDUCING OFF-TARGET EFFECTS
Publication number
20250179453
Publication date
Jun 5, 2025
THE BROAD INSTITUTE, INC.
Feng ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS
Publication number
20250179456
Publication date
Jun 5, 2025
ACRIGEN BIOSCIENCES
David Rabuka
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
FUSION PROTEINS AND USES THEREOF FOR PRECISION EDITING
Publication number
20250179454
Publication date
Jun 5, 2025
MAMMOTH BIOSCIENCES, INC.
Benjamin Julius RAUCH
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR NUCLEIC ACID MODIFICATIONS
Publication number
20250179455
Publication date
Jun 5, 2025
ACRIGEN BIOSCIENCES
David Rabuka
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Materials & Methods for Treatment of Macular Degeneration
Publication number
20250177573
Publication date
Jun 5, 2025
The University of Bristol
Ying Kai Chan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
TYPE I-B CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS
Publication number
20250171811
Publication date
May 29, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
NUCLEIC ACID-GUIDED NICKASE FUSION PROTEINS
Publication number
20250163392
Publication date
May 22, 2025
Inscripta, Inc.
Juhan Kim
C07 - ORGANIC CHEMISTRY
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LIGAND GATED ION CHANNELS AND METHODS OF USE
Publication number
20250163130
Publication date
May 22, 2025
TRAMES BIO, INC.
Anthony Lau
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
COMBINATION BCL11A ENHANCER EDITING
Publication number
20250154466
Publication date
May 15, 2025
The Children's Medical Center Corporation
Daniel E. BAUER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
BASE EDITING OF ANGPTL3 AND METHODS OF USING SAME FOR TREATMENT OF...
Publication number
20250152746
Publication date
May 15, 2025
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
STREPTOCOCCUS PYOGENES-DERIVED CAS9 VARIANT
Publication number
20250154479
Publication date
May 15, 2025
Toolgen Incorporated
Younghoon KIM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR TARGETING NUCLEAR IMPORT SHUTTLES AND...
Publication number
20250144167
Publication date
May 8, 2025
Vanderbilt University
Jack J. Hawiger
C07 - ORGANIC CHEMISTRY
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KIT FOR ANALYZING INTERACTOMES, AND METHOD FOR ANALYZING INTERACTOM...
Publication number
20250147037
Publication date
May 8, 2025
O2MEDI INC.
Tae Hyuk KWON
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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Patent Application
Nucleic Acid-Guided Nucleases
Publication number
20250122490
Publication date
Apr 17, 2025
GigaMune, Inc.
David Scott JOHNSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...