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containing a nuclear localisation signal
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last 30 patents
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Patent Grant
Genome engineering with Type I CRISPR systems in eukaryotic cells
Patent number
11,970,710
Issue date
Apr 30, 2024
Duke University
Charles A. Gersbach
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR/Cas fusion proteins and systems
Patent number
11,965,184
Issue date
Apr 23, 2024
Sigma-Aldrich Co. LLC
Fuqiang Chen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Targeted DNA demethylation method, fusion protein and application t...
Patent number
11,965,187
Issue date
Apr 23, 2024
GUANGZHOU MEDICAL UNIVERSITY
Xi-Yong Yu
C07 - ORGANIC CHEMISTRY
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Patent Grant
Methods and compositions for genome editing in non-dividing cells
Patent number
11,959,094
Issue date
Apr 16, 2024
Salk Institute for Biological Studies
Juan Carlos Izpisua Belmonte
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified cascade ribonucleoproteins and uses thereof
Patent number
11,939,604
Issue date
Mar 26, 2024
Caribou Biosciences, Inc.
Stan Johan Jozef Brouns
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
High efficiency base editors comprising Gam
Patent number
11,932,884
Issue date
Mar 19, 2024
President and Fellows of Harvard College
David R. Liu
C07 - ORGANIC CHEMISTRY
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Patent Grant
Carrier peptide fragment for nucleolar localization and use thereof
Patent number
11,927,589
Issue date
Mar 12, 2024
Toagosei Co., Ltd.
Nahoko Baileykobayashi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Artificial transcription factors and uses thereof
Patent number
11,913,028
Issue date
Feb 27, 2024
Wisconsin Alumni Research Foundation
Asuka Eguchi
C40 - COMBINATORIAL CHEMISTRY
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Patent Grant
Genome engineering with Type I CRISPR systems in eukaryotic cells
Patent number
11,905,526
Issue date
Feb 20, 2024
Duke University
Charles A. Gersbach
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Receptors for ligand-dependent transcriptional regulation
Patent number
11,897,932
Issue date
Feb 13, 2024
The Regents of the University of California
Kole T. Roybal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-guided nucleic acid modifying enzymes and methods of use thereof
Patent number
11,873,504
Issue date
Jan 16, 2024
The Regents of the University of California
Jennifer A Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Regulation of gene expression using engineered nucleases
Patent number
11,845,965
Issue date
Dec 19, 2023
Sangamo Therapeutics, Inc.
Jeffrey C. Miller
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modular DNA-binding domains and methods of use
Patent number
11,827,676
Issue date
Nov 28, 2023
Ulla Bonas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Method for base editing in plants
Patent number
11,820,990
Issue date
Nov 21, 2023
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Caixia Gao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-guided nucleic acid modifying enzymes and methods of use thereof
Patent number
11,795,472
Issue date
Oct 24, 2023
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modulators of Cas9 polypeptide activity and methods of use thereof
Patent number
11,795,208
Issue date
Oct 24, 2023
The Regents of the University of California
Jennifer A Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Recombinant vector comprising ERT2 fused to CAS9
Patent number
11,785,922
Issue date
Oct 17, 2023
Seoul National University Hospital
Eun Ju Lee
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Use of cell-permeable peptide inhibitors of the JNK signal transduc...
Patent number
11,779,628
Issue date
Oct 10, 2023
Xigen Inflammation Ltd.
Jean-Marc Combette
Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
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Patent Grant
Targeted DNA demethylation and methylation
Patent number
11,780,895
Issue date
Oct 10, 2023
The Jackson Laboratory
Albert Cheng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR-Cas complex
Patent number
11,760,985
Issue date
Sep 19, 2023
Wageningen Universiteit
John Van Der Oost
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for treating hemoglobinopathies
Patent number
11,752,202
Issue date
Sep 12, 2023
Beam Therapeutics Inc.
Ian Slaymaker
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Cell penetrating peptides that inhibit IRF5 nuclear localization
Patent number
11,746,133
Issue date
Sep 5, 2023
Rutgers, The State University of New Jersey
Betsy J. Barnes
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
CRISPR-Cas12J effector polypeptides and methods of use thereof
Patent number
11,739,309
Issue date
Aug 29, 2023
The Regents of the University of California
Jennifer A. Doudna
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
CD33 exon 2 deficient donor stem cells for use with CD33 targeting...
Patent number
11,718,659
Issue date
Aug 8, 2023
The Trustees of Columbia University In the City of New York
Siddhartha Mukherjee
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
EPHA3 and multi-valent targeting of tumors
Patent number
11,697,675
Issue date
Jul 11, 2023
Wake Forest University Health Sciences
Waldemar Debinski
G01 - MEASURING TESTING
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Patent Grant
RNA-guided DNA nucleases and uses thereof
Patent number
11,692,182
Issue date
Jul 4, 2023
Monsanto Technology LLC
Jaishree Chittoor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modifying a predetermined target nucle...
Patent number
11,690,866
Issue date
Jul 4, 2023
TARGETGENE BIOTECHNOLOGIES LTD
Yoel Moshe Shiboleth
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
11,685,909
Issue date
Jun 27, 2023
The Regents of the University of California
Jennifer A. Doudna
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for genomic integration
Patent number
11,672,874
Issue date
Jun 13, 2023
Myeloid Therapeutics, Inc.
Daniel Getts
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for genome editing in non-dividing cells
Patent number
11,674,158
Issue date
Jun 13, 2023
Salk Institute for Biological Studies
Juan Carlos Izpisua Belmonte
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
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Patent Application
TARGETED DNA DEMETHYLATION AND METHYLATION
Publication number
20240132557
Publication date
Apr 25, 2024
The Jackson Laboratory
Albert Cheng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENOSINE DEAMINASE BASE EDITORS AND METHODS OF USING SAME TO MODIF...
Publication number
20240132867
Publication date
Apr 25, 2024
Beam Therapeutics Inc.
Nicole GAUDELLI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPR...
Publication number
20240132855
Publication date
Apr 25, 2024
Chroma Medicine, Inc.
Aron Brandon Jaffe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING OF TRANSTHYRETIN GENE
Publication number
20240124536
Publication date
Apr 18, 2024
Beam Therapeutics Inc.
Alexandra C. CHADWICK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9
Publication number
20240124537
Publication date
Apr 18, 2024
Scribe Therapeutics Inc.
Jason FERNANDES
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
USE OF A SPLIT dCAS FUSION PROTEIN SYSTEM FOR EPIGENETIC EDITING
Publication number
20240123088
Publication date
Apr 18, 2024
The Regents of the University of California
Julian Halmai
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NUCLEASE-MEDIATED GENOME EDITING
Publication number
20240101989
Publication date
Mar 28, 2024
WAGENINGEN UNIVERSITEIT
John VAN DER OOST
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DEAD GUIDES FOR CRISPR TRANSCRIPTION FACTORS
Publication number
20240093193
Publication date
Mar 21, 2024
THE BROAD INSTITUTE, INC.
Feng ZHANG
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE
Publication number
20240084274
Publication date
Mar 14, 2024
Renagade Therapeutics Management Inc.
Giedrius Gasiunas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF
Publication number
20240026321
Publication date
Jan 25, 2024
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEAR PROTEIN TARGETING DEUBIQUITINASES AND METHODS OF USE
Publication number
20240026329
Publication date
Jan 25, 2024
FLUX THERAPEUTICS, INC.
Andreas LOEW
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ONE-LOCUS INDUCIBLE PRECISION GUIDED STERILE INSECT TECHNIQUE OR TE...
Publication number
20240023528
Publication date
Jan 25, 2024
The Regents of the University of California
Omar S. Akbari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RAGE PROTEINS FOR THE TREATMENT OF FIBROSIS AND DNA DAMAGE MEDIATED...
Publication number
20240025960
Publication date
Jan 25, 2024
Universitaet Heidelberg
Varun KUMAR
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NOVEL NUCLEIC ACID-GUIDED NUCLEASES
Publication number
20240026322
Publication date
Jan 25, 2024
GigaMune, Inc.
David Scott JOHNSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOUNDS AND METHODS TO TREAT CYSTIC FIBROSIS
Publication number
20240024372
Publication date
Jan 25, 2024
CITY OF HOPE
Kevin V. Morris
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ENHANCEMENT OF PREDICTABLE AND TEMPLATE-FREE GENE EDITING BY THE AS...
Publication number
20230407275
Publication date
Dec 21, 2023
NEW YORK UNIVERSITY
Chengzu Long
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPT...
Publication number
20230399661
Publication date
Dec 14, 2023
FELDAN BIO INC.
David GUAY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR GENOME EDITING IN NON-DIVIDING CELLS
Publication number
20230399663
Publication date
Dec 14, 2023
Salk Institute for Biological Studies
Juan Carlos IZPISUA BELMONTE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PEPTIDE-BASED DELIVERY OF AGENTS
Publication number
20230399378
Publication date
Dec 14, 2023
The Florey Institute of Neuroscience and Mental Health
Fazel SHABANPOOR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRANSCRIPTION ACTIVE COMPLEX TARGETING CANCER DRUG FROM VIRAL PROTE...
Publication number
20230382953
Publication date
Nov 30, 2023
The Regents of the University of California
Yoshihiro Izumiya
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Flp-TAL RECOMBINASES
Publication number
20230383267
Publication date
Nov 30, 2023
Louisiana Tech Research Corporation
Yuri Voziyanov
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MODIFIED CAS12A PROTEIN AND USE THEREOF
Publication number
20230374478
Publication date
Nov 23, 2023
G+FLAS LIFE SCIENCES
Jong Jin PARK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR GENOMIC INTEGRATION
Publication number
20230364265
Publication date
Nov 16, 2023
Myeloid Therapeutics, Inc.
Daniel Getts
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR GENOMIC INTEGRATION
Publication number
20230364266
Publication date
Nov 16, 2023
Myeloid Therapeutics, Inc.
Daniel Getts
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Tracking and Manipulating Cellular RNA via Nuclear Delivery of CRIS...
Publication number
20230365951
Publication date
Nov 16, 2023
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Eugene Yeo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF
Publication number
20230348872
Publication date
Nov 2, 2023
The Regents of the University of California
Jennifer A. Doudna
C07 - ORGANIC CHEMISTRY
Information
Patent Application
RATIONALLY-DESIGNED SYNTHETIC PEPTIDE SHUTTLE AGENTS FOR DELIVERING...
Publication number
20230348537
Publication date
Nov 2, 2023
FELDAN BIO INC.
Thomas DEL'GUIDICE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BASE EDITING OF ANGPTL3 AND METHODS OF USING SAME FOR TREATMENT OF...
Publication number
20230340435
Publication date
Oct 26, 2023
Verve Therapautics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL RNA-GUIDED DNA NUCLEASES AND USES THEREOF
Publication number
20230340441
Publication date
Oct 26, 2023
Monsanto Technology LLC
Jaishree M. Chittoor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF
Publication number
20230332123
Publication date
Oct 19, 2023
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...