Decreased effector function due to an Fc-modification

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C07K2317/71

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2317/00Immunoglobulins specific feautures

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C07K2317/71Decreased effector function due to an Fc-modification

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Patents Grantslast 30 patents

Information Patent Grant
Humanized antibodies with increased stability
- Patent number 12,227,569
- Issue date Feb 18, 2025
- Innate Pharma
- Laurent Gauthier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Caninized human antibodies to human IL-4R alpha
- Patent number 12,221,486
- Issue date Feb 11, 2025
- INTERVET INC.
- Mohamad Morsey
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fc variants with altered binding to FcRn
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- Issue date Feb 4, 2025
- Xencor, Inc.
- Aaron Keith Chamberlain
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-PD-L1 antibodies
- Patent number 12,209,128
- Issue date Jan 28, 2025
- Kymab Limited
- Jamie Campbell
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies specific for FLT3 and their uses
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- Issue date Jan 21, 2025
- PFIZER INC.
- Danielle Elizabeth Dettling
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody compositions comprising Fc mutations and site-specific con...
- Patent number 12,202,893
- Issue date Jan 21, 2025
- TAE Life Sciences, LLC
- Sohye Kang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immunomodulatory antibodies and methods of use thereof
- Patent number 12,195,549
- Issue date Jan 14, 2025
- OncoResponse, Inc.
- Kamal D. Puri
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody targeting CD22 and CD79B
- Patent number 12,180,278
- Issue date Dec 31, 2024
- Janssen Biotech, Inc.
- Kyle J. Bednar
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies to canine interleukin-4 receptor alpha
- Patent number 12,180,288
- Issue date Dec 31, 2024
- INTERVET INC.
- Mohamad Morsey
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and t...
- Patent number 12,173,064
- Issue date Dec 24, 2024
- Janssen Biotech, Inc.
- Raluca Verona
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Information Patent Grant
C-KIT antibodies and method for treating cancer with such
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- Issue date Dec 24, 2024
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- William James Jonathan Finlay
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific polypeptides against CD137
- Patent number 12,173,082
- Issue date Dec 24, 2024
- Alligator Bioscience AB
- Eva Dahlén
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific antigen binding molecules capable of specific binding to...
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- Issue date Nov 19, 2024
- HOFFMANN-LA ROCHE INC.
- Peter Bruenker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
T cell activating bispecific antigen binding molecules
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- Issue date Nov 12, 2024
- HOFFMANN-LA ROCHE INC.
- Marina Bacac
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immunoglobulins and uses thereof
- Patent number 12,134,636
- Issue date Nov 5, 2024
- JANSSEN PHARMACEUTICA NV
- Mark Macielag
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effec...
- Patent number 12,129,299
- Issue date Oct 29, 2024
- ONCOC4, INC.
- Yang Liu
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
HER-2 binding antibodies
- Patent number 12,129,307
- Issue date Oct 29, 2024
- MAB DISCOVERY GMBH
- Stephan Fischer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...
- Patent number 12,122,850
- Issue date Oct 22, 2024
- LamKap Bio gamma AG
- Eric Hatterer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Site-specific antibody-drug conjugation through glycoengineering
- Patent number 12,110,338
- Issue date Oct 8, 2024
- Genzyme Corporation
- Clark Pan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
T cell activating bispecific antigen binding molecules
- Patent number 12,103,982
- Issue date Oct 1, 2024
- HOFFMANN-LA ROCHE INC.
- Christian Klein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fc binding fragments comprising a CD137 antigen-binding site
- Patent number 12,103,976
- Issue date Oct 1, 2024
- invoX Pharma Limited
- Matthew Lakins
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions for modulation of a TREM or TREML protein and methods...
- Patent number 12,091,455
- Issue date Sep 17, 2024
- Yale University
- Andrew Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods comprising anti-NRP2 antibodies
- Patent number 12,065,495
- Issue date Aug 20, 2024
- Atyr Pharma, Inc.
- Luke G. Burman
- G01 - MEASURING TESTING
Information Patent Grant
Methods of treating cancers and enhancing efficacy of T cell redire...
- Patent number 12,065,500
- Issue date Aug 20, 2024
- Janssen Biotech, Inc.
- Homer Adams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CD40 antibodies for use in treatment of Sjögren's syndrome
- Patent number 12,065,499
- Issue date Aug 20, 2024
- Novartis AG
- Pascal Espie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pharmaceutical composition containing tagged site-antihuman antibod...
- Patent number 12,065,503
- Issue date Aug 20, 2024
- Astellas Pharma Inc.
- Jumpei Suemitsu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nucleic acid molecules encoding binding proteins for gastric inhibi...
- Patent number 12,060,430
- Issue date Aug 13, 2024
- Amgen Inc.
- Junming Yie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific IgG antibodies as T cell engagers
- Patent number 12,060,418
- Issue date Aug 13, 2024
- Merus N.V.
- Alexander Berthold Hendrik Bakker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CD3-binding molecules capable of binding to human and non-human CD3
- Patent number 12,049,501
- Issue date Jul 30, 2024
- MacroGenics, In
- Ling Huang
- H01 - BASIC ELECTRIC ELEMENTS
Information Patent Grant
Modified immunoglobulin Fc regions
- Patent number 12,037,380
- Issue date Jul 16, 2024
- MABSOL VE LIMITED
- Geoffrey Hale
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
IL-6 ANTIBODIES
- Publication number 20250059270
- Publication date Feb 20, 2025
- Michael March Schmidt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-PD1 ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS
- Publication number 20250059277
- Publication date Feb 20, 2025
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- Kang LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS
- Publication number 20250051434
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- Merck Sharp & Dohme LLC
- Mehabaw Getahun Derebe
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Humanized Anti-DNAM-1 Antibody
- Publication number 20250051442
- Publication date Feb 13, 2025
- University of Tsukuba
- Akira Shibuya
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS
- Publication number 20250051477
- Publication date Feb 13, 2025
- argenx BV
- Roeland Vanhauwaert
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC PD-L1xCD28 ANTIBODIES AND METHODS OF USE THEREOF
- Publication number 20250043002
- Publication date Feb 6, 2025
- Regeneron Pharmaceuticals, Inc.
- Saida Dadi-Mehmetaj
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MUTANT ANTI-CTLA-4 ANTIBODIES WITH IMPROVED IMMUNOTHERAPEUTIC EFFEC...
- Publication number 20250043003
- Publication date Feb 6, 2025
- ONCOC4, INC.
- Yang Liu
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION THERAPY OF ANTI-PD-1 ACTIVE AGENT, ANTI-TIM-3 ACTIVE AG...
- Publication number 20250034255
- Publication date Jan 30, 2025
- INCYTE CORPORATION
- Paul E. Hoyle
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BISPECIFIC IGG ANTIBODIES AS T CELL ENGAGERS
- Publication number 20250026823
- Publication date Jan 23, 2025
- Merus N.V.
- Alexander Berthold Hendrik Bakker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IMMUNOGLOBULINS AND USES THEREOF
- Publication number 20250026803
- Publication date Jan 23, 2025
- Janssen Pharmaceutica N.V.
- Mark MACIELAG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TRIVALENT TRISPECIFIC ANTIBODY CONSTRUCTS
- Publication number 20250026861
- Publication date Jan 23, 2025
- Invenra Inc.
- Lucas BAILEY
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-NECTIN-4-ANTIBODIES AND USES THEREOF
- Publication number 20250018053
- Publication date Jan 16, 2025
- EMERGENCE THERAPEUTICS GMBH
- Jack ELANDS
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES THAT RECOGNIZE RED BLOOD CELL ANTIGENS
- Publication number 20250011467
- Publication date Jan 9, 2025
- Bloodworks
- James Charles Zimring
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PHARMACEUTICAL COMPOSITION CONTAINING TAGGED SITE-ANTIHUMAN ANTIBOD...
- Publication number 20250009897
- Publication date Jan 9, 2025
- Astellas Pharma Inc.
- Jumpei Suemitsu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES AND METHODS OF USE
- Publication number 20250011471
- Publication date Jan 9, 2025
- Genentch, Inc.
- Yongmei Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED FC VARIANTS
- Publication number 20250011428
- Publication date Jan 9, 2025
- Novartis AG
- Justine Celine Patricia GUYOT
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MODIFIED IMMUNOGLOBULIN FC REGIONS
- Publication number 20250002561
- Publication date Jan 2, 2025
- Mabsolve Limited
- Geoffrey HALE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...
- Publication number 20250002600
- Publication date Jan 2, 2025
- GENMAB A/S
- Alexander MUIK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-IL-11RA ANTIBODIES
- Publication number 20240425606
- Publication date Dec 26, 2024
- Lassen Therapeutics 1, Inc.
- Robert A. HORLICK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF SUPPRESSING MICROGLIAL ACTIVATION
- Publication number 20240425591
- Publication date Dec 26, 2024
- Tiziana Life Sciences PLC
- Howard L. WEINER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS
- Publication number 20240417456
- Publication date Dec 19, 2024
- GlaxoSmithKline Intellectual Property Development Limited
- Steven GRANT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...
- Publication number 20240409653
- Publication date Dec 12, 2024
- GENMAB A/S
- Alexander MUIK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES
- Publication number 20240409668
- Publication date Dec 12, 2024
- EpimAb Biotherapeutics, Inc.
- Chengbin WU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED ANTI-HER2 BISPECIFIC PROTEINS
- Publication number 20240392035
- Publication date Nov 28, 2024
- Denali Therapeutics Inc.
- Abira BANDYOPADHYAY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR INHIBITING MYOSTATIN ACTIVATION BY ADMINISTERING ANTI-P...
- Publication number 20240391989
- Publication date Nov 28, 2024
- Scholar Rock, Inc.
- Adriana Donovan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIGEN-BINDING MOLECULE
- Publication number 20240392020
- Publication date Nov 28, 2024
- Jiangsu Hengrui Pharmaceuticals Co., Ltd.
- Hua Ying
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES
- Publication number 20240376213
- Publication date Nov 14, 2024
- Yeda Research and Development Co. Ltd.
- Ido AMIT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-LATENT TGF-BETA 1 ANTIBODIES AND METHODS OF USE
- Publication number 20240376190
- Publication date Nov 14, 2024
- Chugai SeiYaku Kabushiki Kaisha
- Nasa SAVORY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM
- Publication number 20240368309
- Publication date Nov 7, 2024
- HOFFMANN-LA ROCHE INC.
- Stephan GASSER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OPTIMIZED ANTI-TL1A ANTIBODIES
- Publication number 20240368263
- Publication date Nov 7, 2024
- PROMETHEUS BIOSCIENCES, INC.
- Jeffry D. Watkins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Decreased effector function due to an Fc-modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Humanized antibodies with increased stability

Caninized human antibodies to human IL-4R alpha

Fc variants with altered binding to FcRn

Anti-PD-L1 antibodies

Antibodies specific for FLT3 and their uses

Antibody compositions comprising Fc mutations and site-specific con...

Immunomodulatory antibodies and methods of use thereof

Antibody targeting CD22 and CD79B

Antibodies to canine interleukin-4 receptor alpha

Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and t...

C-KIT antibodies and method for treating cancer with such

Bispecific polypeptides against CD137

Bispecific antigen binding molecules capable of specific binding to...

T cell activating bispecific antigen binding molecules

Immunoglobulins and uses thereof

Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effec...

HER-2 binding antibodies

Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...

Site-specific antibody-drug conjugation through glycoengineering

T cell activating bispecific antigen binding molecules

Fc binding fragments comprising a CD137 antigen-binding site

Compositions for modulation of a TREM or TREML protein and methods...

Compositions and methods comprising anti-NRP2 antibodies

Methods of treating cancers and enhancing efficacy of T cell redire...

Anti-CD40 antibodies for use in treatment of Sjögren's syndrome

Pharmaceutical composition containing tagged site-antihuman antibod...

Nucleic acid molecules encoding binding proteins for gastric inhibi...

Bispecific IgG antibodies as T cell engagers

CD3-binding molecules capable of binding to human and non-human CD3

Modified immunoglobulin Fc regions

Patents Applicationslast 30 patents

IL-6 ANTIBODIES

ANTI-PD1 ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS

MONOVALENT INTERLEUKIN 12 (IL-12) HETERODIMERIC FC PROTEINS

Humanized Anti-DNAM-1 Antibody

ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS

BISPECIFIC PD-L1xCD28 ANTIBODIES AND METHODS OF USE THEREOF

MUTANT ANTI-CTLA-4 ANTIBODIES WITH IMPROVED IMMUNOTHERAPEUTIC EFFEC...

COMBINATION THERAPY OF ANTI-PD-1 ACTIVE AGENT, ANTI-TIM-3 ACTIVE AG...

BISPECIFIC IGG ANTIBODIES AS T CELL ENGAGERS

IMMUNOGLOBULINS AND USES THEREOF

TRIVALENT TRISPECIFIC ANTIBODY CONSTRUCTS

ANTI-NECTIN-4-ANTIBODIES AND USES THEREOF

ANTIBODIES THAT RECOGNIZE RED BLOOD CELL ANTIGENS

PHARMACEUTICAL COMPOSITION CONTAINING TAGGED SITE-ANTIHUMAN ANTIBOD...

ANTIBODIES AND METHODS OF USE

ENGINEERED FC VARIANTS

MODIFIED IMMUNOGLOBULIN FC REGIONS

MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...

ANTI-IL-11RA ANTIBODIES

METHODS OF SUPPRESSING MICROGLIAL ACTIVATION

BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS

MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...

MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES

ENGINEERED ANTI-HER2 BISPECIFIC PROTEINS

METHODS FOR INHIBITING MYOSTATIN ACTIVATION BY ADMINISTERING ANTI-P...

ANTIGEN-BINDING MOLECULE

MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES

ANTI-LATENT TGF-BETA 1 ANTIBODIES AND METHODS OF USE

AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM

OPTIMIZED ANTI-TL1A ANTIBODIES