Decreased effector function due to an Fc-modification

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C07K2317/71

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2317/00Immunoglobulins specific feautures

Current Industry

C07K2317/71Decreased effector function due to an Fc-modification

Industries

Patents Grantslast 30 patents

Information Patent Grant
Antibody targeting CD22 and CD79B
- Patent number 12,180,278
- Issue date Dec 31, 2024
- Janssen Biotech, Inc.
- Kyle J. Bednar
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies to canine interleukin-4 receptor alpha
- Patent number 12,180,288
- Issue date Dec 31, 2024
- INTERVET INC.
- Mohamad Morsey
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and t...
- Patent number 12,173,064
- Issue date Dec 24, 2024
- Janssen Biotech, Inc.
- Raluca Verona
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
C-KIT antibodies and method for treating cancer with such
- Patent number 12,173,067
- Issue date Dec 24, 2024
- Granular Therapeutics Limited
- William James Jonathan Finlay
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific polypeptides against CD137
- Patent number 12,173,082
- Issue date Dec 24, 2024
- Alligator Bioscience AB
- Eva Dahlén
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific antigen binding molecules capable of specific binding to...
- Patent number 12,145,994
- Issue date Nov 19, 2024
- HOFFMANN-LA ROCHE INC.
- Peter Bruenker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
T cell activating bispecific antigen binding molecules
- Patent number 12,139,553
- Issue date Nov 12, 2024
- HOFFMANN-LA ROCHE INC.
- Marina Bacac
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immunoglobulins and uses thereof
- Patent number 12,134,636
- Issue date Nov 5, 2024
- JANSSEN PHARMACEUTICA NV
- Mark Macielag
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effec...
- Patent number 12,129,299
- Issue date Oct 29, 2024
- ONCOC4, INC.
- Yang Liu
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
HER-2 binding antibodies
- Patent number 12,129,307
- Issue date Oct 29, 2024
- MAB DISCOVERY GMBH
- Stephan Fischer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...
- Patent number 12,122,850
- Issue date Oct 22, 2024
- LamKap Bio gamma AG
- Eric Hatterer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Site-specific antibody-drug conjugation through glycoengineering
- Patent number 12,110,338
- Issue date Oct 8, 2024
- Genzyme Corporation
- Clark Pan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
T cell activating bispecific antigen binding molecules
- Patent number 12,103,982
- Issue date Oct 1, 2024
- HOFFMANN-LA ROCHE INC.
- Christian Klein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fc binding fragments comprising a CD137 antigen-binding site
- Patent number 12,103,976
- Issue date Oct 1, 2024
- invoX Pharma Limited
- Matthew Lakins
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions for modulation of a TREM or TREML protein and methods...
- Patent number 12,091,455
- Issue date Sep 17, 2024
- Yale University
- Andrew Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods comprising anti-NRP2 antibodies
- Patent number 12,065,495
- Issue date Aug 20, 2024
- Atyr Pharma, Inc.
- Luke G. Burman
- G01 - MEASURING TESTING
Information Patent Grant
Methods of treating cancers and enhancing efficacy of T cell redire...
- Patent number 12,065,500
- Issue date Aug 20, 2024
- Janssen Biotech, Inc.
- Homer Adams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CD40 antibodies for use in treatment of Sjögren's syndrome
- Patent number 12,065,499
- Issue date Aug 20, 2024
- Novartis AG
- Pascal Espie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pharmaceutical composition containing tagged site-antihuman antibod...
- Patent number 12,065,503
- Issue date Aug 20, 2024
- Astellas Pharma Inc.
- Jumpei Suemitsu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nucleic acid molecules encoding binding proteins for gastric inhibi...
- Patent number 12,060,430
- Issue date Aug 13, 2024
- Amgen Inc.
- Junming Yie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific IgG antibodies as T cell engagers
- Patent number 12,060,418
- Issue date Aug 13, 2024
- Merus N.V.
- Alexander Berthold Hendrik Bakker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CD3-binding molecules capable of binding to human and non-human CD3
- Patent number 12,049,501
- Issue date Jul 30, 2024
- MacroGenics, In
- Ling Huang
- H01 - BASIC ELECTRIC ELEMENTS
Information Patent Grant
Modified immunoglobulin Fc regions
- Patent number 12,037,380
- Issue date Jul 16, 2024
- MABSOL VE LIMITED
- Geoffrey Hale
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant IgG Fc polypeptides and uses thereof
- Patent number 12,030,945
- Issue date Jul 9, 2024
- Seismic Therapeutic, Inc.
- Yen-Lin Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibodies that recognize red blood cell antigens
- Patent number 12,030,956
- Issue date Jul 9, 2024
- Bloodworks NW
- James Charles Zimring
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-OX40 antibody and uses thereof
- Patent number 12,030,951
- Issue date Jul 9, 2024
- Hutchison Medipharma Limited
- Yizhen Yang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
HER2/neu-specific antibodies and methods of using same
- Patent number 12,024,569
- Issue date Jul 2, 2024
- MacroGenics, Inc.
- Leslie S. Johnson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-TIM-3 antibodies and methods of use thereof
- Patent number 12,011,481
- Issue date Jun 18, 2024
- Agenus Inc.
- Marc van Dijk
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating cancers and enhancing efficacy of T cell redire...
- Patent number 12,012,461
- Issue date Jun 18, 2024
- Janssen Biotech, Inc.
- Homer Adams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for altering body composition by administering anti-pro/lat...
- Patent number 12,006,359
- Issue date Jun 11, 2024
- SCHOLAR ROCK, INC.
- Adriana Donovan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
MODIFIED IMMUNOGLOBULIN FC REGIONS
- Publication number 20250002561
- Publication date Jan 2, 2025
- Mabsolve Limited
- Geoffrey HALE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...
- Publication number 20250002600
- Publication date Jan 2, 2025
- GENMAB A/S
- Alexander MUIK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-IL-11RA ANTIBODIES
- Publication number 20240425606
- Publication date Dec 26, 2024
- Lassen Therapeutics 1, Inc.
- Robert A. HORLICK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF SUPPRESSING MICROGLIAL ACTIVATION
- Publication number 20240425591
- Publication date Dec 26, 2024
- Tiziana Life Sciences PLC
- Howard L. WEINER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS
- Publication number 20240417456
- Publication date Dec 19, 2024
- GlaxoSmithKline Intellectual Property Development Limited
- Steven GRANT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...
- Publication number 20240409653
- Publication date Dec 12, 2024
- GENMAB A/S
- Alexander MUIK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES
- Publication number 20240409668
- Publication date Dec 12, 2024
- EpimAb Biotherapeutics, Inc.
- Chengbin WU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED ANTI-HER2 BISPECIFIC PROTEINS
- Publication number 20240392035
- Publication date Nov 28, 2024
- Denali Therapeutics Inc.
- Abira BANDYOPADHYAY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR INHIBITING MYOSTATIN ACTIVATION BY ADMINISTERING ANTI-P...
- Publication number 20240391989
- Publication date Nov 28, 2024
- Scholar Rock, Inc.
- Adriana Donovan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIGEN-BINDING MOLECULE
- Publication number 20240392020
- Publication date Nov 28, 2024
- Jiangsu Hengrui Pharmaceuticals Co., Ltd.
- Hua Ying
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES
- Publication number 20240376213
- Publication date Nov 14, 2024
- Yeda Research and Development Co. Ltd.
- Ido AMIT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-LATENT TGF-BETA 1 ANTIBODIES AND METHODS OF USE
- Publication number 20240376190
- Publication date Nov 14, 2024
- Chugai SeiYaku Kabushiki Kaisha
- Nasa SAVORY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OPTIMIZED ANTI-TL1A ANTIBODIES
- Publication number 20240368263
- Publication date Nov 7, 2024
- PROMETHEUS BIOSCIENCES, INC.
- Jeffry D. Watkins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM
- Publication number 20240368309
- Publication date Nov 7, 2024
- HOFFMANN-LA ROCHE INC.
- Stephan GASSER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MOLECULES FOR MODULATING THE IMMUNE SYSTEM AND USES THEREOF
- Publication number 20240368283
- Publication date Nov 7, 2024
- Seismic Therapeutic, Inc.
- Nathan Higginson-Scott
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD117+ CELLS
- Publication number 20240360238
- Publication date Oct 31, 2024
- CRISPR Therapeutics AG
- Bradley R. Pearse
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IMMUNOCONJUGATE MOLECULES AND RELATED METHODS AND COMPOSITIONS THEREOF
- Publication number 20240358849
- Publication date Oct 31, 2024
- SUZHOU FUSE BIOSCIENCES LIMITED
- Qufei LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND M...
- Publication number 20240360209
- Publication date Oct 31, 2024
- NEURACLE SCIENCE CO., LTD.
- Bongcheol KIM
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-PD-L1 AND IL-2 CYTOKINES
- Publication number 20240360218
- Publication date Oct 31, 2024
- Kymab Limited
- Jamie CAMPBELL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES TARGETING IMMUNOSUPPRESSIVE B CELLS
- Publication number 20240352156
- Publication date Oct 24, 2024
- Biograph 55, Inc.
- Leonard PRESTA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
- Publication number 20240343802
- Publication date Oct 17, 2024
- ZYMEWORKS BC INC.
- Gordon Yiu Kon Ng
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TISSUE-DIRECTED ANTIBODIES AND METHODS OF USING THE SAME
- Publication number 20240342260
- Publication date Oct 17, 2024
- ZAG Bio, Inc.
- Alan Crane
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY
- Publication number 20240343810
- Publication date Oct 17, 2024
- Kymab Limited
- Jamie CAMPBELL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR AUGMENTING ANTIBODY MEDIATED RECEPTOR...
- Publication number 20240336694
- Publication date Oct 10, 2024
- Dana-Farber Cancer Institute, Inc.
- Wayne A. Marasco
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION...
- Publication number 20240327544
- Publication date Oct 3, 2024
- BIONTECH SE
- Ugur SAHIN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INTERLEUKIN-2 MUTEINS FOR THE EXPANSION OF T-REGULATORY CELLS
- Publication number 20240327485
- Publication date Oct 3, 2024
- Amgen Inc.
- Marc Alain GAVIN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES AGAINST PD-L1
- Publication number 20240317861
- Publication date Sep 26, 2024
- GENMAB A/S
- Isil ALTINTAS
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODULATION OF ANTIBODY FUNCTION VIA SIALIC ACID MODIFICATION
- Publication number 20240309075
- Publication date Sep 19, 2024
- Children's Hospital Medical Center
- Sing Sing Way
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-OX40 ANTIBODY AND USES THEREOF
- Publication number 20240301077
- Publication date Sep 12, 2024
- Hutchison Medipharma Limited
- Yizhen YANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF TREATING CANCERS AND ENHANCING EFFICACY OF T CELL REDIRE...
- Publication number 20240301083
- Publication date Sep 12, 2024
- JANSSEN BIOTECH, INC.
- Homer Adams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Decreased effector function due to an Fc-modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Antibody targeting CD22 and CD79B

Antibodies to canine interleukin-4 receptor alpha

Antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3 and t...

C-KIT antibodies and method for treating cancer with such

Bispecific polypeptides against CD137

Bispecific antigen binding molecules capable of specific binding to...

T cell activating bispecific antigen binding molecules

Immunoglobulins and uses thereof

Mutant anti-CTLA-4 antibodies with improved immunotherapeutic effec...

HER-2 binding antibodies

Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...

Site-specific antibody-drug conjugation through glycoengineering

T cell activating bispecific antigen binding molecules

Fc binding fragments comprising a CD137 antigen-binding site

Compositions for modulation of a TREM or TREML protein and methods...

Compositions and methods comprising anti-NRP2 antibodies

Methods of treating cancers and enhancing efficacy of T cell redire...

Anti-CD40 antibodies for use in treatment of Sjögren's syndrome

Pharmaceutical composition containing tagged site-antihuman antibod...

Nucleic acid molecules encoding binding proteins for gastric inhibi...

Bispecific IgG antibodies as T cell engagers

CD3-binding molecules capable of binding to human and non-human CD3

Modified immunoglobulin Fc regions

Variant IgG Fc polypeptides and uses thereof

Antibodies that recognize red blood cell antigens

Anti-OX40 antibody and uses thereof

HER2/neu-specific antibodies and methods of using same

Anti-TIM-3 antibodies and methods of use thereof

Methods of treating cancers and enhancing efficacy of T cell redire...

Methods for altering body composition by administering anti-pro/lat...

Patents Applicationslast 30 patents

MODIFIED IMMUNOGLOBULIN FC REGIONS

MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...

ANTI-IL-11RA ANTIBODIES

METHODS OF SUPPRESSING MICROGLIAL ACTIVATION

BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS

MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION...

MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES

ENGINEERED ANTI-HER2 BISPECIFIC PROTEINS

METHODS FOR INHIBITING MYOSTATIN ACTIVATION BY ADMINISTERING ANTI-P...

ANTIGEN-BINDING MOLECULE

MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES

ANTI-LATENT TGF-BETA 1 ANTIBODIES AND METHODS OF USE

OPTIMIZED ANTI-TL1A ANTIBODIES

AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM

MOLECULES FOR MODULATING THE IMMUNE SYSTEM AND USES THEREOF

COMPOSITIONS AND METHODS FOR THE DEPLETION OF CD117+ CELLS

IMMUNOCONJUGATE MOLECULES AND RELATED METHODS AND COMPOSITIONS THEREOF

ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND M...

ANTI-PD-L1 AND IL-2 CYTOKINES

ANTIBODIES TARGETING IMMUNOSUPPRESSIVE B CELLS

Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs

TISSUE-DIRECTED ANTIBODIES AND METHODS OF USING THE SAME

MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY

COMPOSITIONS AND METHODS FOR AUGMENTING ANTIBODY MEDIATED RECEPTOR...

MULTISPECIFIC BINDING AGENTS AGAINST CD40 AND CD137 IN COMBINATION...

INTERLEUKIN-2 MUTEINS FOR THE EXPANSION OF T-REGULATORY CELLS

ANTIBODIES AGAINST PD-L1

MODULATION OF ANTIBODY FUNCTION VIA SIALIC ACID MODIFICATION

ANTI-OX40 ANTIBODY AND USES THEREOF

METHODS OF TREATING CANCERS AND ENHANCING EFFICACY OF T CELL REDIRE...