having a combination of backbone and sugar modifications

Industry

CPC
C12N2310/346

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

Current Industry

C12N2310/346having a combination of backbone and sugar modifications

Industries

Patents Grantslast 30 patents

Information Patent Grant
Methods and compositions for inhibiting PMP22 expression
- Patent number 11,959,080
- Issue date Apr 16, 2024
- Ionis Pharmaceuticals, Inc.
- Gene Hung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeted control of pests and pathogens by plant delivery of 2′F-AN...
- Patent number 11,946,058
- Issue date Apr 2, 2024
- The United States of America, as represented by the Secretary of Agriculture
- Wayne B. Hunter
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antisense oligonucleotides targeting SCN2A for the treatment of SCN...
- Patent number 11,939,582
- Issue date Mar 26, 2024
- RogCon, Inc.
- Steven Petrou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA interference mediated inhibition of gene expression using short...
- Patent number 11,932,854
- Issue date Mar 19, 2024
- SIRNA Therapeutics, Inc.
- Mark Cancilla
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds and methods for reducing ATXN2 expression
- Patent number 11,926,825
- Issue date Mar 12, 2024
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Oligonucleotide therapy for Leber congenital amaurosis
- Patent number 11,920,132
- Issue date Mar 5, 2024
- ProQR Therapeutics II B.V.
- Patricia Coromoto Biasutto
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for inhibiting expression of RRM2 genes
- Patent number 11,920,134
- Issue date Mar 5, 2024
- Arrowhead Pharmaceuticals, Inc.
- John Frederick Boylan
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Nucleic acid oligomers and uses therefor
- Patent number 11,911,410
- Issue date Feb 27, 2024
- REPLUCA PTY LTD
- Derek Richard
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeted nucleic acid conjugate compositions
- Patent number 11,896,672
- Issue date Feb 13, 2024
- ARBUTUS BIOPHARMA CORPORATION
- James Heyes
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Reducing intron retention
- Patent number 11,891,605
- Issue date Feb 6, 2024
- University of Southampton
- Igor Vorechovsky
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for treating multiple sclerosis using antisense oligonucleo...
- Patent number 11,891,606
- Issue date Feb 6, 2024
- Antisense Therapeutics Ltd
- George Tachas
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT R...
- Patent number 11,884,920
- Issue date Jan 30, 2024
- Arrowhead Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for reducing LRRK2 expression
- Patent number 11,873,495
- Issue date Jan 16, 2024
- Ionis Pharmaceuticals, Inc.
- Tracy A. Cole
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antiviral agents
- Patent number 11,866,706
- Issue date Jan 9, 2024
- Meharry Medical College
- Donald J. Alcendor
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
- Patent number 11,851,655
- Issue date Dec 26, 2023
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions comprising chemically modified guide RNAs for CRISPR/C...
- Patent number 11,851,652
- Issue date Dec 26, 2023
- THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR
- Matthew H. Porteus
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides for inducing paternal UBE3A expression
- Patent number 11,852,627
- Issue date Dec 26, 2023
- HOFFMANN-LA ROCHE INC.
- Veronica Costa
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Structure-guided chemical modification of guide RNA and its applica...
- Patent number 11,845,933
- Issue date Dec 19, 2023
- Massachusetts Institute of Technology
- Hao Yin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for inhibiting gene expression of Hif2alpha
- Patent number 11,840,688
- Issue date Dec 12, 2023
- Arrowhead Pharmaceuticals, Inc.
- So Wong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for increasing STMN2 expression
- Patent number 11,833,168
- Issue date Dec 5, 2023
- Ionis Pharmaceuticals, Inc.
- Huynh-Hoa Bui
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions for modulating Ataxin 2 expression
- Patent number 11,834,660
- Issue date Dec 5, 2023
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
BCL11A guide delivery
- Patent number 11,788,087
- Issue date Oct 17, 2023
- The Children's Medical Center Corporation
- Daniel Bauer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for treating Alzheimer's disease
- Patent number 11,781,135
- Issue date Oct 10, 2023
- Washington University
- Timothy M. Miller
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Defined multi-conjugates oligonucleotides
- Patent number 11,767,531
- Issue date Sep 26, 2023
- MPEG LA, LLC
- Philipp Hadwiger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and their uses directed to huntingtin
- Patent number 11,761,000
- Issue date Sep 19, 2023
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conjugated oligonucleotides
- Patent number 11,753,638
- Issue date Sep 12, 2023
- University of Massachusetts
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Allele specific modulators of P23H rhodopsin
- Patent number 11,744,846
- Issue date Sep 5, 2023
- Susan F. Murray
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Angleman syndrome antisense treatment
- Patent number 11,739,328
- Issue date Aug 29, 2023
- The Texas A&M University System
- Scott Victor Dindot
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotide compositions and methods thereof
- Patent number 11,739,325
- Issue date Aug 29, 2023
- WAVE LIFE SCIENCES LTD.
- Chandra Vargeese
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compounds and methods for the modulation of amyloid-β precursor pro...
- Patent number 11,732,260
- Issue date Aug 22, 2023
- Ionis Pharmaceuticals, Inc.
- Frank Rigo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
- Publication number 20240150756
- Publication date May 9, 2024
- WAVE LIFE SCIENCES LTD.
- Maria David Frank-Kamenetsky
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
- Publication number 20240141350
- Publication date May 2, 2024
- REGULUS THERAPEUTICS INC.
- Charles R. ALLERSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ALPHA-1 ANTITRYPSIN (AAT) RNAI AGENTS, COMPOSITIONS INCLUDING AAT R...
- Publication number 20240141351
- Publication date May 2, 2024
- Arrowhead Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
- Publication number 20240117347
- Publication date Apr 11, 2024
- WAVE LIFE SCIENCES LTD.
- David Charles Donnell Butler
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES USING TR...
- Publication number 20240100080
- Publication date Mar 28, 2024
- Alnylam Pharmaceuticals, Inc.
- Amy Chan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYNUCLEOTIDE AGENTS TARGETING PROGRAMMED CELL DEATH 1 LIGAND 1 (P...
- Publication number 20240102020
- Publication date Mar 28, 2024
- Alnylam Pharmaceuticals, Inc.
- Gregory Hinkle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJ...
- Publication number 20240093201
- Publication date Mar 21, 2024
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION
- Publication number 20240085402
- Publication date Mar 14, 2024
- HOFFMANN-LA ROCHE INC.
- Veronica COSTA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUNDS AND METHODS FOR REDUCING ATXN3 EXPRESSION
- Publication number 20240082291
- Publication date Mar 14, 2024
- Ionis Pharmaceuticals, Inc.
- Susan M. Freier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONJUGATED OLIGONUCLEOTIDES
- Publication number 20240084297
- Publication date Mar 14, 2024
- University of Massachusetts
- Anastasia KHVOROVA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIAC DISEASES
- Publication number 20240067963
- Publication date Feb 29, 2024
- Jaan Biotherapeutics LLC
- Bhawanjit Kaur Brar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTISENSE COMPOUNDS
- Publication number 20240058370
- Publication date Feb 22, 2024
- Ionis Pharmaceuticals, Inc.
- Eric E. Swayze
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS
- Publication number 20240043840
- Publication date Feb 8, 2024
- New York Genome Center, Inc.
- Neville E. Sanjana
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGOMERS AND OLIGOMER CONJUGATES
- Publication number 20240035032
- Publication date Feb 1, 2024
- HOFFMANN-LA ROCHE INC.
- Hassan JAVANBAKH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Stabilized saRNA Compositions and Methods of Use
- Publication number 20240018519
- Publication date Jan 18, 2024
- MINA THERAPEUTICS LIMITED
- Hans E. Huber
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES
- Publication number 20240011029
- Publication date Jan 11, 2024
- Janssen Pharmaceutica N.V.
- Andreas EBNETH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES CONTAINING 2'-DEOXY-2'FLUORO-BETA-D-ARABINOSE NUCL...
- Publication number 20240000824
- Publication date Jan 4, 2024
- CITY OF HOPE
- John J. Rossi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GUIDE RNA WITH CHEMICAL MODIFICATIONS
- Publication number 20230416733
- Publication date Dec 28, 2023
- Agilent Technologies, Inc.
- Daniel E. Ryan
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND METHODS FOR MODULATING PMP22
- Publication number 20230374519
- Publication date Nov 23, 2023
- Ionis Pharmaceuticals, Inc.
- Eric E. Swayze
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMBINATION
- Publication number 20230374503
- Publication date Nov 23, 2023
- AstraZeneca AB
- Richard Woessner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOUNDS AND METHODS FOR REDUCING APOE EXPRESSION
- Publication number 20230357770
- Publication date Nov 9, 2023
- Ionis Pharmaceuticals, Inc.
- Tracy A. Cole
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION
- Publication number 20230357776
- Publication date Nov 9, 2023
- Ionis Pharmaceuticals, Inc.
- Thazha P. Prakash
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
- Publication number 20230348904
- Publication date Nov 2, 2023
- SIRNA THERAPEUTICS, INC.
- Brian Allen Carr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS
- Publication number 20230340473
- Publication date Oct 26, 2023
- Alnylam Pharmaceuticals, Inc.
- Yukio Ando
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGOMERS HAVING BICYCLIC SCAFFOLD MOIETIES
- Publication number 20230330128
- Publication date Oct 19, 2023
- BioMarin Technologies B.V.
- Judith Christina Theodora Van DEUTEKOM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDES FOR REDUCTION OF PD-L1 EXPRESSION
- Publication number 20230331837
- Publication date Oct 19, 2023
- HOFFMANN-LA ROCHE INC.
- Lykke PEDERSEN
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Application
ANGELMAN SYNDROME ANTISENSE TREATMENT
- Publication number 20230332152
- Publication date Oct 19, 2023
- THE TEXAS A&M UNIVERSITY SYSTEM
- Scott Victor Dindot
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPLEMENT COMPONENT C1R INHIBITORS FOR TREATING A NEUROLOGICAL DIS...
- Publication number 20230323362
- Publication date Oct 12, 2023
- Genentech, Inc.
- Alexander MUNK
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTISENSE OLIGONUCLEOTIDES FOR RNA EDITING
- Publication number 20230323346
- Publication date Oct 12, 2023
- ProQR Therapeutics II B.V.
- Lenka VAN SINT FIET
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS FOR MODULATING TAU EXPRESSION
- Publication number 20230323351
- Publication date Oct 12, 2023
- Biogen MA Inc.
- Holly Kordasiewicz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

having a combination of backbone and sugar modifications

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Methods and compositions for inhibiting PMP22 expression

Targeted control of pests and pathogens by plant delivery of 2′F-AN...

Antisense oligonucleotides targeting SCN2A for the treatment of SCN...

RNA interference mediated inhibition of gene expression using short...

Compounds and methods for reducing ATXN2 expression

Oligonucleotide therapy for Leber congenital amaurosis

Compositions and methods for inhibiting expression of RRM2 genes

Nucleic acid oligomers and uses therefor

Targeted nucleic acid conjugate compositions

Reducing intron retention

Methods for treating multiple sclerosis using antisense oligonucleo...

Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT R...

Compounds and methods for reducing LRRK2 expression

Antiviral agents

Compositions and methods for modulating apolipoprotein (a) expression

Compositions comprising chemically modified guide RNAs for CRISPR/C...

Oligonucleotides for inducing paternal UBE3A expression

Structure-guided chemical modification of guide RNA and its applica...

Compositions and methods for inhibiting gene expression of Hif2alpha

Compounds and methods for increasing STMN2 expression

Compositions for modulating Ataxin 2 expression

BCL11A guide delivery

Methods for treating Alzheimer's disease

Defined multi-conjugates oligonucleotides

Compositions and their uses directed to huntingtin

Conjugated oligonucleotides

Allele specific modulators of P23H rhodopsin

Angleman syndrome antisense treatment

Oligonucleotide compositions and methods thereof

Compounds and methods for the modulation of amyloid-β precursor pro...

Patents Applicationslast 30 patents

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE

ALPHA-1 ANTITRYPSIN (AAT) RNAI AGENTS, COMPOSITIONS INCLUDING AAT R...

OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

METHODS FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES USING TR...

POLYNUCLEOTIDE AGENTS TARGETING PROGRAMMED CELL DEATH 1 LIGAND 1 (P...

COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJ...

OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION

COMPOUNDS AND METHODS FOR REDUCING ATXN3 EXPRESSION

CONJUGATED OLIGONUCLEOTIDES

COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIAC DISEASES

ANTISENSE COMPOUNDS

CHEMICALLY MODIFIED CRISPR-CAS13 GUIDE RNAS

OLIGOMERS AND OLIGOMER CONJUGATES

Stabilized saRNA Compositions and Methods of Use

MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES

OLIGONUCLEOTIDES CONTAINING 2'-DEOXY-2'FLUORO-BETA-D-ARABINOSE NUCL...

GUIDE RNA WITH CHEMICAL MODIFICATIONS

COMPOUNDS AND METHODS FOR MODULATING PMP22

COMBINATION

COMPOUNDS AND METHODS FOR REDUCING APOE EXPRESSION

COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION

SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS

SIRNA THERAPY FOR TRANSTHYRETIN (TTR) RELATED OCULAR AMYLOIDOSIS

OLIGOMERS HAVING BICYCLIC SCAFFOLD MOIETIES

OLIGONUCLEOTIDES FOR REDUCTION OF PD-L1 EXPRESSION

ANGELMAN SYNDROME ANTISENSE TREATMENT

COMPLEMENT COMPONENT C1R INHIBITORS FOR TREATING A NEUROLOGICAL DIS...

ANTISENSE OLIGONUCLEOTIDES FOR RNA EDITING

COMPOSITIONS FOR MODULATING TAU EXPRESSION