having a mismatch or nick in at least one of the strands

Industry

CPC
C12N2310/533

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

Current Industry

C12N2310/533having a mismatch or nick in at least one of the strands

Industries

Patents Grantslast 30 patents

Information Patent Grant
Modulatory polynucleotides
- Patent number 12,084,659
- Issue date Sep 10, 2024
- VOYAGER THERAPEUTICS, INC.
- Dinah Wen-Yee Sah
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 12,077,756
- Issue date Sep 3, 2024
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Systems, methods, and compositions for targeted nucleic acid editing
- Patent number 11,866,697
- Issue date Jan 9, 2024
- The Broad Institute, Inc.
- Feng Zhang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chemically modified single-stranded RNA-editing oligonucleotides
- Patent number 11,851,656
- Issue date Dec 26, 2023
- ProQR Therapeutics II B.V.
- Janne Juha Turunen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic editing
- Patent number 11,827,880
- Issue date Nov 28, 2023
- Shape Therapeutics Inc.
- David Huss
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant RNAi
- Patent number 11,781,137
- Issue date Oct 10, 2023
- Genzyme Corporation
- Lisa M. Stanek
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeted RNA editing
- Patent number 11,781,134
- Issue date Oct 10, 2023
- ProQR Therapeutics II B.V.
- Bart Klein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for editing RNAs
- Patent number 11,702,658
- Issue date Jul 18, 2023
- EDIGENE THERAPEUTICS (BEIJING) INC.
- Pengfei Yuan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genome editing using effector oligonucleotides for therapeutic trea...
- Patent number 11,680,265
- Issue date Jun 20, 2023
- Research Foundation to Cure AIDS, Inc.
- Kambiz Shekdar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
RNA duplexes with single stranded phosphorothioate nucleotide regio...
- Patent number 11,667,915
- Issue date Jun 6, 2023
- Phio Pharmaceuticals Corp.
- Tod M. Woolf
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for the specific inhibition of antithrombi...
- Patent number 11,667,918
- Issue date Jun 6, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 11,634,713
- Issue date Apr 25, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 11,597,929
- Issue date Mar 7, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for generating a deletion library and for...
- Patent number 11,584,931
- Issue date Feb 21, 2023
- The J. David Gladstone Institutes
- Leor S. Weinberger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Reducing beta-catenin expression to potentiate immunotherapy
- Patent number 11,572,559
- Issue date Feb 7, 2023
- Dicerna Pharmaceuticals, Inc.
- Shanthi Ganesh
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for inhibiting GYS2 expression
- Patent number 11,572,562
- Issue date Feb 7, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,549,109
- Issue date Jan 10, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted RIG-I agonists: compositions and methods thereof
- Patent number 11,542,505
- Issue date Jan 3, 2023
- Merck Sharp & Dohme LLC
- Craig A. Parish
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic compositions
- Patent number 11,530,408
- Issue date Dec 20, 2022
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,427,822
- Issue date Aug 30, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 11,414,664
- Issue date Aug 16, 2022
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 11,408,003
- Issue date Aug 9, 2022
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for treating cancers
- Patent number 11,400,170
- Issue date Aug 2, 2022
- Gradalis, Inc.
- John Nemunaitis
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,401,517
- Issue date Aug 2, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Extended dicer substrate agents and methods for the specific inhibi...
- Patent number 11,359,198
- Issue date Jun 14, 2022
- Dicerna Pharmaceuticals, Inc.
- Bob Dale Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic inhibition of lactate dehydrogenase and agents therefor
- Patent number 11,359,203
- Issue date Jun 14, 2022
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods of nucleic acid-targeting nucleic acids
- Patent number 11,312,953
- Issue date Apr 26, 2022
- Caribou Biosciences, Inc.
- Andrew Paul May
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modulatory polynucleotides
- Patent number 11,193,129
- Issue date Dec 7, 2021
- VOYAGER THERAPEUTICS, INC.
- Dinah Wen-Yee Sah
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mixed tricyclo-DNA, 2′-modified RNA oligonucleotide compositions an...
- Patent number 11,118,179
- Issue date Sep 14, 2021
- SYNTHENA AG
- Wolfgang Andreas Renner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic inhibition of lactate dehydrogenase and agents therefor
- Patent number 11,053,502
- Issue date Jul 6, 2021
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
BC200 RNA DECOY COMPOUNDS AND METHODS OF USE FOR THE TREATMENT OF A...
- Publication number 20240336927
- Publication date Oct 10, 2024
- The Research Foundation for the State University of New York
- Henri Tiedge
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Compositions and Methods for Silencing MYOC Expression
- Publication number 20240318175
- Publication date Sep 26, 2024
- Alnylam Pharmaceuticals, Inc.
- ADAM CASTORENO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Therapeutic Editing
- Publication number 20240279650
- Publication date Aug 22, 2024
- Shape Therapeutics Inc.
- David HUSS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES
- Publication number 20240271131
- Publication date Aug 15, 2024
- ProQR Therapeutics II B.V.
- Janne Juha Turunen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Asymmetric Short Duplex DNA as a Novel Gene Silencing Technology an...
- Publication number 20240271137
- Publication date Aug 15, 2024
- 1Globe Health Institute LLC
- Chiang J. LI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
- Publication number 20240254486
- Publication date Aug 1, 2024
- Alnylam Pharmaceuticals, Inc.
- Brian Bettencourt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REDIRECTING RISC FOR RNA EDITING
- Publication number 20240209339
- Publication date Jun 27, 2024
- Alnylam Pharmaceuticals, Inc.
- Min TAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA SILENCING AGENTS AND METHODS OF USE
- Publication number 20240191229
- Publication date Jun 13, 2024
- ADARx Pharmaceuticals, Inc.
- Zhen Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT RNAi
- Publication number 20240182896
- Publication date Jun 6, 2024
- Genzyme Corporation
- Lisa M. STANEK
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENOME EDITING USING EFFECTOR OLIGONUCLEOTIDES FOR THERAPEUTIC TREA...
- Publication number 20240182906
- Publication date Jun 6, 2024
- Research Foundation to Cure AIDS, Inc.
- Kambiz SHEKDAR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Modified Guide RNAs Comprising an Internal Linker for Gene Editing
- Publication number 20240150761
- Publication date May 9, 2024
- INTELLIA THERAPEUTICS, INC.
- Sabin Mulepati
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TARGETED RNA EDITING
- Publication number 20240141336
- Publication date May 2, 2024
- ProQR Therapeutics II B.V.
- Bart Klein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING
- Publication number 20240076651
- Publication date Mar 7, 2024
- THE BROAD INSTITUTE, INC.
- Feng Zhang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND COMPOSITIONS FOR GENERATING A DELETION LIBRARY AND FOR...
- Publication number 20240035021
- Publication date Feb 1, 2024
- THE J. DAVID GLADSTONE INSTITUTES
- Leor S. Weinberger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REDUCING BETA-CATENIN EXPRESSION TO POTENTIATE IMMUNOTHERAPY
- Publication number 20230392148
- Publication date Dec 7, 2023
- Dicerna Pharmaceuticals, Inc.
- Shanthi Ganesh
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING GYS2 EXPRESSION
- Publication number 20230365974
- Publication date Nov 16, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID CONSTRUCTS FOR DELIVERING POLYNUCLEOTIDES INTO EXOSOMES
- Publication number 20230287408
- Publication date Sep 14, 2023
- ReNeuron Limited
- Randolph CORTELING
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS OF DNA MOLECULES, METHODS OF MAKING THEREFOR, AND METH...
- Publication number 20230272432
- Publication date Aug 31, 2023
- Anjarium Biosciences AG
- Joel de Beer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CIRCULAR miRNA SPONGES
- Publication number 20230272389
- Publication date Aug 31, 2023
- National University of Singapore
- Annadoray Lavenniah
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Compositions and Methods for Modifying Target RNAs
- Publication number 20230193279
- Publication date Jun 22, 2023
- Shape Therapeutics Inc.
- Adrian BRIGGS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Modified Double-Stranded RNA Agents
- Publication number 20230183701
- Publication date Jun 15, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RIG-I Agonists and Methods of Using Same
- Publication number 20230159923
- Publication date May 25, 2023
- Yale University
- Anna Marie Pyle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITION AND METHODS FOR IMPROVING HEART FUNCTION AND TREATING H...
- Publication number 20230140435
- Publication date May 4, 2023
- The Trustees of the University of Pennsylvania
- Benjamin L. Prosser
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
- Publication number 20230110876
- Publication date Apr 13, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASY...
- Publication number 20230111150
- Publication date Apr 13, 2023
- Dicerna Pharmaceuticals, Inc.
- Bob D. Brown
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Therapeutic Editing
- Publication number 20230044119
- Publication date Feb 9, 2023
- Shape Therapeutics Inc.
- David HUSS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
- Publication number 20220403382
- Publication date Dec 22, 2022
- Alnylam Pharmaceuticals, Inc.
- Brian Bettencourt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
THERAPEUTIC INHIBITION OF LACTATE DEHYDROGENASE AND AGENTS THEREFOR
- Publication number 20220396799
- Publication date Dec 15, 2022
- Dicerna Pharmaceuticals, Inc.
- Bob D. BROWN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
- Publication number 20220389424
- Publication date Dec 8, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OLIGONUCLEOTIDE, AND TARGET RNA SITE-SPECIFIC EDITING METHOD
- Publication number 20220325281
- Publication date Oct 13, 2022
- FUKUOKA UNIVERSITY
- Masatora FUKUDA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

having a mismatch or nick in at least one of the strands

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Modulatory polynucleotides

Extended dicer substrate agents and methods for the specific inhibi...

Systems, methods, and compositions for targeted nucleic acid editing

Chemically modified single-stranded RNA-editing oligonucleotides

Therapeutic editing

Variant RNAi

Targeted RNA editing

Methods and compositions for editing RNAs

Genome editing using effector oligonucleotides for therapeutic trea...

RNA duplexes with single stranded phosphorothioate nucleotide regio...

Methods and compositions for the specific inhibition of antithrombi...

Extended dicer substrate agents and methods for the specific inhibi...

Extended dicer substrate agents and methods for the specific inhibi...

Methods and compositions for generating a deletion library and for...

Reducing beta-catenin expression to potentiate immunotherapy

Compositions and methods for inhibiting GYS2 expression

Modified double-stranded RNA agents

Substituted RIG-I agonists: compositions and methods thereof

Therapeutic compositions

Modified double-stranded RNA agents

Extended dicer substrate agents and methods for the specific inhibi...

Extended dicer substrate agents and methods for the specific inhibi...

Methods for treating cancers

Modified double-stranded RNA agents

Extended dicer substrate agents and methods for the specific inhibi...

Therapeutic inhibition of lactate dehydrogenase and agents therefor

Compositions and methods of nucleic acid-targeting nucleic acids

Modulatory polynucleotides

Mixed tricyclo-DNA, 2′-modified RNA oligonucleotide compositions an...

Therapeutic inhibition of lactate dehydrogenase and agents therefor

Patents Applicationslast 30 patents

BC200 RNA DECOY COMPOUNDS AND METHODS OF USE FOR THE TREATMENT OF A...

Compositions and Methods for Silencing MYOC Expression

Therapeutic Editing

CHEMICALLY MODIFIED SINGLE-STRANDED RNA-EDITING OLIGONUCLEOTIDES

Asymmetric Short Duplex DNA as a Novel Gene Silencing Technology an...

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

REDIRECTING RISC FOR RNA EDITING

RNA SILENCING AGENTS AND METHODS OF USE

VARIANT RNAi

GENOME EDITING USING EFFECTOR OLIGONUCLEOTIDES FOR THERAPEUTIC TREA...

Modified Guide RNAs Comprising an Internal Linker for Gene Editing

TARGETED RNA EDITING

SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING

METHODS AND COMPOSITIONS FOR GENERATING A DELETION LIBRARY AND FOR...

REDUCING BETA-CATENIN EXPRESSION TO POTENTIATE IMMUNOTHERAPY

COMPOSITIONS AND METHODS FOR INHIBITING GYS2 EXPRESSION

NUCLEIC ACID CONSTRUCTS FOR DELIVERING POLYNUCLEOTIDES INTO EXOSOMES

COMPOSITIONS OF DNA MOLECULES, METHODS OF MAKING THEREFOR, AND METH...

CIRCULAR miRNA SPONGES

Compositions and Methods for Modifying Target RNAs

Modified Double-Stranded RNA Agents

RIG-I Agonists and Methods of Using Same

COMPOSITION AND METHODS FOR IMPROVING HEART FUNCTION AND TREATING H...

MODIFIED DOUBLE-STRANDED RNA AGENTS

METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF KRAS BY ASY...

Therapeutic Editing

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE

THERAPEUTIC INHIBITION OF LACTATE DEHYDROGENASE AND AGENTS THEREFOR

MODIFIED DOUBLE-STRANDED RNA AGENTS

OLIGONUCLEOTIDE, AND TARGET RNA SITE-SPECIFIC EDITING METHOD