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C12N2310/3231
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
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C12N2310/3231
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Patents Grants
last 30 patents
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Patent Grant
Bispecific antisense oligonucleotides for dystrophin exon skipping
Patent number
12,331,293
Issue date
Jun 17, 2025
BIOMARIN TECHNOLOGIES B.V.
Judith Christina Theodora van Deutekom
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
MicroRNA compounds and methods for modulating mir-21 activity
Patent number
12,331,294
Issue date
Jun 17, 2025
Sanofi
Balkrishen Bhat
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulation of gene transcription using antisense oligonucleotides t...
Patent number
12,319,916
Issue date
Jun 3, 2025
CAMP4 THERAPEUTICS CORPORATION
Alfica Sehgal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nanoparticle formulations for delivery of nucleic acid complexes
Patent number
12,318,489
Issue date
Jun 3, 2025
Translate Bio MA, Inc.
Fatih Ozsolak
B82 - NANO-TECHNOLOGY
Information
Patent Grant
Oligonucleotides targeting frataxin and related methods
Patent number
12,312,585
Issue date
May 27, 2025
UNIVERSITY OF MASSACHUSETTS
Feng Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid molecule for reduction of PAPD5 and PAPD7 mRNA for tre...
Patent number
12,303,525
Issue date
May 20, 2025
Hoffman-La Roche Inc.
Susanne Kammler
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
Patent number
12,291,709
Issue date
May 6, 2025
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oral delivery of antisense conjugates targeting PCSK9
Patent number
12,291,708
Issue date
May 6, 2025
CiVi Biopharma, Inc.
Henrik Oerum
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligomers and oligomer conjugates
Patent number
12,281,307
Issue date
Apr 22, 2025
HOFFMANN-LA ROCHE INC.
Hassan Javanbakht
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing prion expression
Patent number
12,281,305
Issue date
Apr 22, 2025
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Conjugated antisense compounds and their use
Patent number
12,275,940
Issue date
Apr 15, 2025
Ionis Pharmaceuticals, Inc.
Michael Oestergaard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for inducing paternal UBE3A expression
Patent number
12,259,380
Issue date
Mar 25, 2025
HOFFMANN-LA ROCHE INC.
Veronica Costa
G01 - MEASURING TESTING
Information
Patent Grant
REVERSIR™ compounds
Patent number
12,241,064
Issue date
Mar 4, 2025
Alnylam Pharmaceuticals, Inc.
Vasant Jadhav
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides targeting alpha-synuclein and uses thereof
Patent number
12,241,065
Issue date
Mar 4, 2025
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Therapeutic oligonucleotides
Patent number
12,234,455
Issue date
Feb 25, 2025
IFOM Fondazione Istituto FIRC di Oncologia Molecolare
Fabrizio d′Adda di Fagagna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid-polypeptide compositions and uses thereof
Patent number
12,234,290
Issue date
Feb 25, 2025
AVIDITY BIOSCIENCES, INC.
Andrew John Geall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified compounds and uses thereof
Patent number
12,234,447
Issue date
Feb 25, 2025
Ionis Pharmaceuticals, Inc.
Punit P. Seth
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating SCN2A
Patent number
12,227,746
Issue date
Feb 18, 2025
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide agonists targeting progranulin
Patent number
12,203,071
Issue date
Jan 21, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating ATXN1
Patent number
12,180,479
Issue date
Dec 31, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dynamic pharmacokinetic-modifying anchors
Patent number
12,180,477
Issue date
Dec 31, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for facilitating delivery of synthetic nuc...
Patent number
12,178,855
Issue date
Dec 31, 2024
Translate Bio MA, Inc.
Balkrishen Bhat
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides targeting alpha-synuclein and uses thereof
Patent number
12,180,478
Issue date
Dec 31, 2024
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for improving strand biased
Patent number
12,173,287
Issue date
Dec 24, 2024
Alnylam Pharmaceuticals, Inc.
Rubina G. Parmar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of APOL1 expression
Patent number
12,168,766
Issue date
Dec 17, 2024
Astrazeneca AB
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified double-stranded RNA agents
Patent number
12,168,767
Issue date
Dec 17, 2024
Alnylam Pharmaceuticals, Inc.
Martin Maier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
Patent number
12,163,132
Issue date
Dec 10, 2024
Children's National Medical Center
Yi-Wen Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
Patent number
12,163,129
Issue date
Dec 10, 2024
University of Massachusetts
Robert H. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
12,163,131
Issue date
Dec 10, 2024
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulating the cellular stress response
Patent number
12,157,888
Issue date
Dec 3, 2024
The General Hospital Corporation
Jeannie T. Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
METHODS FOR THE TREATMENT OF NUCLEOTIDE REPEAT EXPANSION DISORDERS...
Publication number
20250197856
Publication date
Jun 19, 2025
Takeda Pharmaceuticals U.S.A. Inc.
Irina ANTONIJEVIC
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LNCRNA TRANSCRIPTS IN MELANOMAGENESIS
Publication number
20250197864
Publication date
Jun 19, 2025
The Regents of the University of California
Susana Ortiz Urda
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF DESIGNING CONDITIONAL-ACTIVATABLE SMALL INTERFERING RNA...
Publication number
20250191692
Publication date
Jun 12, 2025
Switch Therapeutics Inc.
Si-ping Han
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
siRNA SUPPRESSING EXPRESSION OF TRANSFERRIN RECEPTOR 2
Publication number
20250188478
Publication date
Jun 12, 2025
DAIICHI SANKYO COMPANY, LIMITED
Makoto KOIZUMI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOME...
Publication number
20250188470
Publication date
Jun 12, 2025
Alnylam Pharmaceuticals, Inc.
Muthiah MANOHARAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SIGNAL ACTIVATABLE NUCLEIC ACID CONSTRUCTS WITH WOBBLE BASE PAIRINGS
Publication number
20250188454
Publication date
Jun 12, 2025
Switch Therapeutics Inc.
Si-ping Han
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES TARGETING ALPHA-SYNUCLEIN AND USES THEREOF
Publication number
20250188463
Publication date
Jun 12, 2025
Bristol-Myers Squibb Company
Richard E. OLSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NONCOVALENTLY BRANCHED OLIGONUCLEOTIDE COMPOSITIONS
Publication number
20250188471
Publication date
Jun 12, 2025
Atalanta Therapeutics, Inc.
Matthew HASSLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHEMICALLY MODIFIED OLIGONUCLEOTIDE HAVING RNAi ACTIVITY
Publication number
20250188477
Publication date
Jun 12, 2025
DAIICHI SANKYO COMPANY, LIMITED
Makoto KOIZUMI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF USING OLIGOMERIC COMPOUNDS TO TREAT SCN2A-RELATED DISORDERS
Publication number
20250179503
Publication date
Jun 5, 2025
PRAXIS PRECISION MEDICINES, INC.
Michael S. Oldham
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Publication number
20250171544
Publication date
May 29, 2025
Avidity Biosciences, Inc.
Andrew John GEALL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR IMPROVING STRAND BIASED
Publication number
20250163417
Publication date
May 22, 2025
ALNYLAM PHARMACEUTICALS,INC.
Rubina G. PARMAR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Brush polymer-oligonucleotide conjugates for the treatment of muscu...
Publication number
20250163418
Publication date
May 22, 2025
Northeastern University
Ke Zhang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
Publication number
20250154506
Publication date
May 15, 2025
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES TARGETING RNA BINDING PROTEIN SITES
Publication number
20250145996
Publication date
May 8, 2025
HOFFMANN-LA ROCHE INC.
Jessica Marine Aurore BASTIEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Composition and Methods for Modulating Nuclear Enriched Abundant Tr...
Publication number
20250136983
Publication date
May 1, 2025
MUSC Foundation for Research Development
Hongkuan Fan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHANNEL MODULATORS
Publication number
20250136987
Publication date
May 1, 2025
Auckland UniServices Limited
Colin Richard GREEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES TARGETING ALPHA-SYNUCLEIN AND USES THEREOF
Publication number
20250136988
Publication date
May 1, 2025
Bristol-Myers Squibb Company
Richard E. OLSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATION OF MICRORNA-335-5P FOR THE TREATMENT OF SODIUM CHANNELOP...
Publication number
20250136980
Publication date
May 1, 2025
Royal College of Surgeons in Ireland
David HENSHALL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATION OF ALPHA SYNUCLEIN EXPRESSION
Publication number
20250136982
Publication date
May 1, 2025
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE AGONISTS TARGETING PROGRANULIN
Publication number
20250136984
Publication date
May 1, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES TARGETING ADENOSINE KINASE
Publication number
20250136990
Publication date
May 1, 2025
NEUmiRNA Therapeutics Aps
Markus Sakari Kauppinen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR PREPARING CAPPED CIRCULAR RNA MOLECULES
Publication number
20250129400
Publication date
Apr 24, 2025
THE BROAD INSTITUTE, INC.
Xiao WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MICRORNA INHIBITOR THERAPY IN SYSTEMIC LUPUS ERYTHEMATOSUS
Publication number
20250127149
Publication date
Apr 24, 2025
Wael N. JARJOUR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS FOR INHIBITING AMANZI
Publication number
20250115909
Publication date
Apr 10, 2025
LEMBA BV
Ezio Fok
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS FOR INHIBITION OF IL-1BETA EXPRESSION
Publication number
20250115914
Publication date
Apr 10, 2025
LEMBA BV
Makiri Kawasaki
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR INDUCING PATERNAL UBE3A EXPRESSION
Publication number
20250116656
Publication date
Apr 10, 2025
HOFFMANN-LA ROCHE INC.
Veronica COSTA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATING THE CELLULAR STRESS RESPONSE
Publication number
20250115910
Publication date
Apr 10, 2025
The General Hospital Corporation
Jeannie T. Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING STAT6
Publication number
20250115904
Publication date
Apr 10, 2025
LONZA SALES AG
Dalia BURZYN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHEMICALLY MODIFIED ANTISENSE OLIGONUCLEOTIDES (ASOS) AND COMPOSITI...
Publication number
20250101418
Publication date
Mar 27, 2025
Eberhard-Karls-Universitat Tubingen
Thorsten Stafforst
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...