Immunoglobulins having two or more different antigen binding sites

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C07K16/468

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K16/00Immunoglobulins [IGs]

Current Industry

C07K16/468Immunoglobulins having two or more different antigen binding sites

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Antibody targeting CD22 and CD79B
- Patent number 12,180,278
- Issue date Dec 31, 2024
- Janssen Biotech, Inc.
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multispecific antibody analogs comprising a common light chain, and...
- Patent number 12,180,299
- Issue date Dec 31, 2024
- Adimab, LLC
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method for in vivo generation of multispecific antibodies from mono...
- Patent number 12,180,279
- Issue date Dec 31, 2024
- HOFFMANN-LA ROCHE INC.
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Heterodimeric antibodies that bind fibroblast activation protein
- Patent number 12,180,302
- Issue date Dec 31, 2024
- Xencor, Inc.
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Bispecific molecules comprising an HIV-1 envelope targeting arm
- Patent number 12,173,051
- Issue date Dec 24, 2024
- Duke University
- Barton F. Haynes
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic use of mitochondria and combined mitochondrial agents
- Patent number 12,168,700
- Issue date Dec 17, 2024
- Children's Medical Center Corporation
- James D. McCully
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific antibody for cancer immunotherapy
- Patent number 12,168,695
- Issue date Dec 17, 2024
- H. Lee Moffitt Cancer Center & Research Institute, Inc.
- Hatem Soliman
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Readily isolated bispecific antibodies with native immunoglobulin f...
- Patent number 12,157,758
- Issue date Dec 3, 2024
- REGENERON PHARMACEUTICALS, INC.
- Samuel Davis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
IL27RAlpha binding molecules and methods of use
- Patent number 12,157,773
- Issue date Dec 3, 2024
- Synthekine, Inc.
- Robert Kastelein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multimeric protein purity determination
- Patent number 12,158,473
- Issue date Dec 3, 2024
- REGENERON PHARMACEUTICALS, INC.
- Kathir Muthusamy
- G01 - MEASURING TESTING
Information Patent Grant
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
- Patent number 12,152,076
- Issue date Nov 26, 2024
- Xencor, Inc.
- Matthew Bernett
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
T cell activating bispecific antigen binding molecules
- Patent number 12,139,553
- Issue date Nov 12, 2024
- HOFFMANN-LA ROCHE INC.
- Marina Bacac
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Covalent multi-specific antibody
- Patent number 12,134,661
- Issue date Nov 5, 2024
- Chimagen Biosciences, Ltd.
- Zhenhao Zhou
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Constrained conditionally activated binding proteins
- Patent number 12,128,102
- Issue date Oct 29, 2024
- Takeda Pharmaceutical Company Limited
- Patrick Baeuerle
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Optimized variants of anti-VEGF antibodies
- Patent number 12,121,586
- Issue date Oct 22, 2024
- Genentech, Inc.
- Patrick Koenig
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
IFNGR binding synthetic cytokines and methods of use
- Patent number 12,122,839
- Issue date Oct 22, 2024
- Synthekine, Inc.
- Robert Kastelein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...
- Patent number 12,122,850
- Issue date Oct 22, 2024
- LamKap Bio gamma AG
- Eric Hatterer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods and means for the production of Ig-like molecules
- Patent number 12,123,043
- Issue date Oct 22, 2024
- Merus N.V.
- Cornelis Adriaan De Kruif
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T cell activating bispecific antigen binding molecules
- Patent number 12,103,982
- Issue date Oct 1, 2024
- HOFFMANN-LA ROCHE INC.
- Christian Klein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific chimeric antigen receptors, encoding polynucleotides and...
- Patent number 12,091,459
- Issue date Sep 17, 2024
- Seattle Children's Hospital
- Michael Jensen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific antibody
- Patent number 12,091,461
- Issue date Sep 17, 2024
- Ono Pharmaceutical Co., Ltd.
- Shiro Shibayama
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-ROR antibody constructs
- Patent number 12,084,496
- Issue date Sep 10, 2024
- Exelixis, Inc.
- Lucas Bailey
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Trispecific binding proteins and methods of use
- Patent number 12,084,518
- Issue date Sep 10, 2024
- HARPOON THERAPEUTICS, INC.
- Patrick Baeuerle
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibodies binding BCMA and CD3 and uses thereof
- Patent number 12,084,520
- Issue date Sep 10, 2024
- Beijing Mabworks Biotech Co., Ltd.
- Fangjie Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods, compositions and kits for treating a subject using a recom...
- Patent number 12,084,519
- Issue date Sep 10, 2024
- Trustees of Tufts College
- Charles B. Shoemaker
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Proteins comprising CD3 antigen binding domains and uses thereof
- Patent number 12,084,501
- Issue date Sep 10, 2024
- Janssen Biotech, Inc.
- Adam Zwolak
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Use of car and bite technology coupled with an SCFV from an antibod...
- Patent number 12,076,378
- Issue date Sep 3, 2024
- Kim Leslie O'Neill
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multispecific antigen-binding molecules for cell targeting and uses...
- Patent number 12,077,603
- Issue date Sep 3, 2024
- REGENERON PHARMACEUTICALS, INC.
- Lauric Haber
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Site-specific crosslinking of antibodies
- Patent number 12,071,487
- Issue date Aug 27, 2024
- Life Technologies Corporation
- Brian Agnew
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific antigen binding construct
- Patent number 12,071,486
- Issue date Aug 27, 2024
- argenx BV
- Sebastian Van Der Woning
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
- Publication number 20240425616
- Publication date Dec 26, 2024
- Roche Glycart AG
- Oliver AST
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD OF MANUFACTURING BISPECIFIC ANTIBODIES, BISPECIFIC ANTIBODIE...
- Publication number 20240425617
- Publication date Dec 26, 2024
- Novartis AG
- Michael Otto BARDROFF
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETERODIMERIC ANTIBODIES THAT BIND PROSTATE SPECIFIC MEMBRANE ANTIG...
- Publication number 20240417466
- Publication date Dec 19, 2024
- Xencor, Inc.
- John R. Desjarlais
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Antibodies Reactive with B7-H3, Immunologically Active Fragments Th...
- Publication number 20240409661
- Publication date Dec 12, 2024
- MacroGenics, Inc.
- Leslie S. Johnson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES
- Publication number 20240409668
- Publication date Dec 12, 2024
- EpimAb Biotherapeutics, Inc.
- Chengbin WU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF
- Publication number 20240400720
- Publication date Dec 5, 2024
- NOVIMMUNE SA
- Krzysztof M. MASTERNAK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
USES OF DLL3-TARGETING MULTISPECIFIC ANTIGEN-BINDING MOLECULES
- Publication number 20240400721
- Publication date Dec 5, 2024
- Chugai SeiYaku Kabushiki Kaisha
- Sotaro Naoi
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CLDN6
- Publication number 20240400675
- Publication date Dec 5, 2024
- Xencor, Inc.
- Matthew S. Faber
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF
- Publication number 20240400682
- Publication date Dec 5, 2024
- SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE
- Michael Jensen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYPEPTIDE MODIFICATION METHOD FOR PURIFYING POLYPEPTIDE MULTIMERS
- Publication number 20240391952
- Publication date Nov 28, 2024
- Chugai SeiYaku Kabushiki Kaisha
- Tomoyuki Igawa
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIBODIES BINDING CD3 AND USES THEREOF
- Publication number 20240392042
- Publication date Nov 28, 2024
- BEIJING MABWORKS BIOTECH CO., LTD
- Fangjie LIU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-ROR ANTIBODY CONSTRUCTS
- Publication number 20240392002
- Publication date Nov 28, 2024
- Exelixis, Inc.
- Lucas BAILEY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-LAG3 BISPECIFIC ANTIBODY, PHARMACEUTICAL COMPOSITION AND USE
- Publication number 20240392040
- Publication date Nov 28, 2024
- AKESO HUIKE (SHANGHAI) CO. LTD.
- Peng ZHANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Site-Specific Crosslinking of Antibodies
- Publication number 20240392041
- Publication date Nov 28, 2024
- Life Technologies Corporation
- Brian Agnew
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CD20 AND CD22 TARGETING ANTIGEN-BINDING MOLECULES FOR USE IN PROLIF...
- Publication number 20240384006
- Publication date Nov 21, 2024
- AMGEN RESEARCH (MUNICH) GMBH
- Marc Panzer
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PROTEIN SPECIFICALLY BINDING TO PD-1 AND PHARMACEUTICAL USE THEREOF
- Publication number 20240376204
- Publication date Nov 14, 2024
- JIANGSU HENGRUI PHARMACEUTICALS CO., LTD.
- Zhiliang CAO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IL23R BINDING MOLECULES AND METHODS OF USE
- Publication number 20240376217
- Publication date Nov 14, 2024
- Synthekine, Inc.
- Robert Kastelein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-NKp30 ANTIBODIES AND METHODS OF USE
- Publication number 20240376195
- Publication date Nov 14, 2024
- BeiGene, LTD.
- Liu XUE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES
- Publication number 20240376213
- Publication date Nov 14, 2024
- Yeda Research and Development Co. Ltd.
- Ido AMIT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
USE OF APPROVED BISPECIFIC EGFR AND MET SPECIFIC ANTIBODY DRUG PROD...
- Publication number 20240368310
- Publication date Nov 7, 2024
- JANSSEN BIOTECH, INC.
- Roland Knoblauch
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIGEN-BINDING MOLECULES FOR CELL TARGETING AND USES...
- Publication number 20240368312
- Publication date Nov 7, 2024
- Regeneron Pharmaceuticals, Inc.
- Lauric Haber
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM
- Publication number 20240368309
- Publication date Nov 7, 2024
- HOFFMANN-LA ROCHE INC.
- Stephan GASSER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BISPECIFIC ANTIGEN BINDING CONSTRUCT
- Publication number 20240368311
- Publication date Nov 7, 2024
- argenx BV
- Sebastian VAN DER WONING
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-PD-L1 AND IL-2 CYTOKINES
- Publication number 20240360218
- Publication date Oct 31, 2024
- Kymab Limited
- Jamie CAMPBELL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COVALENT MULTI-SPECIFIC ANTIBODY
- Publication number 20240352155
- Publication date Oct 24, 2024
- CHIMAGEN BIOSCIENCES, LTD.
- Zhenhao ZHOU
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIBODIES TARGETING IMMUNOSUPPRESSIVE B CELLS
- Publication number 20240352156
- Publication date Oct 24, 2024
- Biograph 55, Inc.
- Leonard PRESTA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR TREATING MULTIPLE MYELOMA
- Publication number 20240352140
- Publication date Oct 24, 2024
- JANSSEN BIOTECH, INC.
- Homer Adams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES
- Publication number 20240344102
- Publication date Oct 17, 2024
- Merus N.V.
- Cornelis Adriaan DE KRUIF
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Tetravalent Antibody-Drug Conjugates and Use Thereof
- Publication number 20240342304
- Publication date Oct 17, 2024
- Bliss Biopharmaceutical (Hangzhou) Co., Ltd.
- Yuhong Zhou
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY
- Publication number 20240343810
- Publication date Oct 17, 2024
- Kymab Limited
- Jamie CAMPBELL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Immunoglobulins having two or more different antigen binding sites

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Antibody targeting CD22 and CD79B

Multispecific antibody analogs comprising a common light chain, and...

Method for in vivo generation of multispecific antibodies from mono...

Heterodimeric antibodies that bind fibroblast activation protein

Bispecific molecules comprising an HIV-1 envelope targeting arm

Therapeutic use of mitochondria and combined mitochondrial agents

Bispecific antibody for cancer immunotherapy

Readily isolated bispecific antibodies with native immunoglobulin f...

IL27RAlpha binding molecules and methods of use

Multimeric protein purity determination

Bispecific and monospecific antibodies using novel anti-PD-1 sequences

T cell activating bispecific antigen binding molecules

Covalent multi-specific antibody

Constrained conditionally activated binding proteins

Optimized variants of anti-VEGF antibodies

IFNGR binding synthetic cytokines and methods of use

Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination...

Methods and means for the production of Ig-like molecules

T cell activating bispecific antigen binding molecules

Bispecific chimeric antigen receptors, encoding polynucleotides and...

Bispecific antibody

Anti-ROR antibody constructs

Trispecific binding proteins and methods of use

Antibodies binding BCMA and CD3 and uses thereof

Methods, compositions and kits for treating a subject using a recom...

Proteins comprising CD3 antigen binding domains and uses thereof

Use of car and bite technology coupled with an SCFV from an antibod...

Multispecific antigen-binding molecules for cell targeting and uses...

Site-specific crosslinking of antibodies

Bispecific antigen binding construct

Patents Applicationslast 30 patents

BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES

METHOD OF MANUFACTURING BISPECIFIC ANTIBODIES, BISPECIFIC ANTIBODIE...

HETERODIMERIC ANTIBODIES THAT BIND PROSTATE SPECIFIC MEMBRANE ANTIG...

Antibodies Reactive with B7-H3, Immunologically Active Fragments Th...

MONOVALENT ASYMMETRIC TANDEM FAB BISPECIFIC ANTIBODIES

ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF

USES OF DLL3-TARGETING MULTISPECIFIC ANTIGEN-BINDING MOLECULES

HETERODIMERIC ANTIBODIES THAT BIND CD3 AND CLDN6

BISPECIFIC CHIMERIC ANTIGEN RECEPTORS AND THERAPEUTIC USES THEREOF

POLYPEPTIDE MODIFICATION METHOD FOR PURIFYING POLYPEPTIDE MULTIMERS

ANTIBODIES BINDING CD3 AND USES THEREOF

ANTI-ROR ANTIBODY CONSTRUCTS

ANTI-LAG3 BISPECIFIC ANTIBODY, PHARMACEUTICAL COMPOSITION AND USE

Site-Specific Crosslinking of Antibodies

CD20 AND CD22 TARGETING ANTIGEN-BINDING MOLECULES FOR USE IN PROLIF...

PROTEIN SPECIFICALLY BINDING TO PD-1 AND PHARMACEUTICAL USE THEREOF

IL23R BINDING MOLECULES AND METHODS OF USE

ANTI-NKp30 ANTIBODIES AND METHODS OF USE

MULTISPECIFIC ANTIBODIES FOR USE IN TREATING DISEASES

USE OF APPROVED BISPECIFIC EGFR AND MET SPECIFIC ANTIBODY DRUG PROD...

MULTISPECIFIC ANTIGEN-BINDING MOLECULES FOR CELL TARGETING AND USES...

AGONISTIC CD28 ANTIGEN BINDING MOLECULES TARGETING EPCAM

BISPECIFIC ANTIGEN BINDING CONSTRUCT

ANTI-PD-L1 AND IL-2 CYTOKINES

COVALENT MULTI-SPECIFIC ANTIBODY

ANTIBODIES TARGETING IMMUNOSUPPRESSIVE B CELLS

METHODS FOR TREATING MULTIPLE MYELOMA

METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES

Tetravalent Antibody-Drug Conjugates and Use Thereof

MULTISPECIFIC ANTIBODIES FOR IMMUNO-ONCOLOGY