Ligases forming phosphoric ester bonds (6.5)

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Patents Grantslast 30 patents

Information Patent Grant
Method for generating higher order genome editing libraries
- Patent number 12,091,656
- Issue date Sep 17, 2024
- Johann Wolfgang Goethe-Universität Frankfur
- Manuel Kaulich
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for assembling nucleic acids
- Patent number 12,018,316
- Issue date Jun 25, 2024
- Telesis Bio Inc.
- John E. Gill
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for identifying a location of an RNA in a biological sample
- Patent number 11,952,627
- Issue date Apr 9, 2024
- 10X GENOMICS, INC.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Increasing capture efficiency of spatial assays
- Patent number 11,898,205
- Issue date Feb 13, 2024
- 10X GENOMICS, INC.
- Felice Alessio Bava
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 11,834,711
- Issue date Dec 5, 2023
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T4 DNA ligase variants with increased thermostability
- Patent number 11,788,082
- Issue date Oct 17, 2023
- AbClonal Science, Inc.
- Zhenyu Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for identifying a location of an RNA in a biological sample
- Patent number 11,761,038
- Issue date Sep 19, 2023
- 10X GENOMICS, INC.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for attaching one or more polynucleotide binding proteins to...
- Patent number 11,725,235
- Issue date Aug 15, 2023
- Oxford Nanopore Technologies PLC
- Andrew John Heron
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T4 DNA ligase variants with increased resistance to salt
- Patent number 11,685,913
- Issue date Jun 27, 2023
- AbClonal Science, Inc.
- Alicia DiCicco
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Enzymatic ligation of nucleic acids
- Patent number 11,661,629
- Issue date May 30, 2023
- Life Technologies Corporation
- Stephen Hendricks
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
In vitro recombination method
- Patent number 11,542,529
- Issue date Jan 3, 2023
- Codex DNA, Inc.
- Lei Young
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Highly specific circular proximity ligation assay
- Patent number 11,530,438
- Issue date Dec 20, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Henrik H. J. Persson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Enhanced adaptor ligation
- Patent number 11,279,972
- Issue date Mar 22, 2022
- Swift Biosciences, Inc.
- Vladimir Makarov
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 11,180,800
- Issue date Nov 23, 2021
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Particles coated with catalysts useful for splicing nucleic acids
- Patent number 11,136,595
- Issue date Oct 5, 2021
- Emory University
- Khalid Salaita
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Multiple ligase compositions, systems, and methods
- Patent number 11,124,789
- Issue date Sep 21, 2021
- RGENE, INC.
- Yu Zheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method to alter Chinese hamster ovary cell line stability
- Patent number 11,124,772
- Issue date Sep 21, 2021
- University of Delaware
- Kelvin Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method of preparing cell free nucleic acid molecules by in situ amp...
- Patent number 11,015,213
- Issue date May 25, 2021
- CIRCULOGENE THERANOSTICS, LLC
- Chen-Hsiung Yeh
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Double-strand DNA break quantification method
- Patent number 10,907,199
- Issue date Feb 2, 2021
- Marie-Chantal Gregoire
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
DNA ligase variants
- Patent number 10,837,009
- Issue date Nov 17, 2020
- New England Biolabs, Inc.
- Jennifer Ong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Molecular detection using ligation amplification
- Patent number 10,781,477
- Issue date Sep 22, 2020
- ARATOME, LLC
- Jay Trautman
- G01 - MEASURING TESTING
Information Patent Grant
Method for establishing eukaryotic expression cell line of CD36 mut...
- Patent number 10,711,046
- Issue date Jul 14, 2020
- NAN-NING INSTITUTE OF TRANSFUSION MEDICINE
- Guoguang Wu
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 10,697,008
- Issue date Jun 30, 2020
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Construction of next generation sequencing (NGS) libraries using co...
- Patent number 10,683,542
- Issue date Jun 16, 2020
- Integrated DNA Technologies, Inc.
- Zachary Zwirko
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Processes for the production of oligonucleotides
- Patent number 10,640,812
- Issue date May 5, 2020
- GlaxoSmithKline Intellectual Property Development Limited
- Andreas Crameri
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Low sequence bias single-stranded DNA ligation
- Patent number 10,640,828
- Issue date May 5, 2020
- The Penn State Research Foundation
- Philip C. Bevilacqua
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multiple ligase compositions, systems, and methods
- Patent number 10,626,390
- Issue date Apr 21, 2020
- RGENE, INC.
- Yu Zheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Ligase activity
- Patent number 10,597,650
- Issue date Mar 24, 2020
- New England Biolabs, Inc.
- Gregory Lohman
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Ligase activity
- Patent number 10,597,710
- Issue date Mar 24, 2020
- New England Biolabs, Inc.
- Gregory Lohman
- G01 - MEASURING TESTING
Information Patent Grant
In vitro recombination method
- Patent number 10,577,629
- Issue date Mar 3, 2020
- SGI-DNA, Inc.
- Lei Young
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
T7 DNA Ligase Variants R129D with Increased Specificity for Cohesiv...
- Publication number 20240392336
- Publication date Nov 28, 2024
- AbClonal Science, Inc.
- Dapeng Sun
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CIRCULAR GUIDE RNAs FOR CRISPR/CAS EDITING SYSTEMS
- Publication number 20240376468
- Publication date Nov 14, 2024
- Beam Therapeutics Inc.
- Brian CAFFERTY
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID
- Publication number 20240352443
- Publication date Oct 24, 2024
- DNA Script
- Sandrine CRETON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED DNA LIGASE VARIANTS
- Publication number 20240309353
- Publication date Sep 19, 2024
- Codexis, Inc.
- Jacob Hansen Artz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TARGETED RNA EDITING BY LEVERAGING ENDOGENOUS ADAR USING ENGINEERED...
- Publication number 20240309368
- Publication date Sep 19, 2024
- Peking University
- Wensheng WEI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
- Publication number 20240301488
- Publication date Sep 12, 2024
- 10X Genomics, Inc.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
- Publication number 20240294979
- Publication date Sep 5, 2024
- Karius, Inc.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES
- Publication number 20240287566
- Publication date Aug 29, 2024
- Andreas CRAMERI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods for Assembling Nucleic Acids
- Publication number 20240287581
- Publication date Aug 29, 2024
- Telesis Bio, Inc.
- John E. Gill
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF
- Publication number 20240277872
- Publication date Aug 22, 2024
- THE BROAD INSTITUTE, INC.
- Xiao Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T7 DNA Ligase Variants Having Increased Ligation Efficiency
- Publication number 20240247246
- Publication date Jul 25, 2024
- AbClonal Science, Inc.
- Dapeng Sun
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MATERIAL AND METHOD FOR PREPARATION OF SMALL, SINGLE-STRANDED DNA C...
- Publication number 20240240216
- Publication date Jul 18, 2024
- Purdue Research Foundation
- Chengde Mao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED RNA LIGASE VARIANTS
- Publication number 20240209343
- Publication date Jun 27, 2024
- Codexis, Inc.
- Rachelle Copeland
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE-FREE ENZYMATIC SYNTHES...
- Publication number 20240209407
- Publication date Jun 27, 2024
- CAMENA BIOSCIENCE LIMITED
- Derek STEMPLE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID PROCESSING VIA CIRCULARIZATION
- Publication number 20240209346
- Publication date Jun 27, 2024
- 10X Genomics, Inc.
- Shankar Shastry
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS
- Publication number 20240182968
- Publication date Jun 6, 2024
- 10X Genomics, Inc.
- Felice Alessio Bava
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods of Library Preparation
- Publication number 20240175010
- Publication date May 30, 2024
- Illumina, Inc.
- Allison Yunghans
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF ENZYMATICALLY REPAIRING CLEAVED RNAS AND DETECTING THEREOF
- Publication number 20240076748
- Publication date Mar 7, 2024
- Institut Pasteur de Montevideo
- Juan Pablo Tosar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T4 DNA Ligase Variants with Increased Resistance to Salt
- Publication number 20240067951
- Publication date Feb 29, 2024
- AbClonal Science, Inc.
- Alicia DiCicco
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO...
- Publication number 20240026441
- Publication date Jan 25, 2024
- Oxford Nanopre Technologies PLC
- Andrew John Heron
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HIGH-SPEED PHOTO-CROSS-LINKING LINKER FOR MOLECULAR INTERACTION ANA...
- Publication number 20240002838
- Publication date Jan 4, 2024
- Saitama University
- Naoto Nemoto
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
- Publication number 20230383344
- Publication date Nov 30, 2023
- 10X Genomics, Inc.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR DISPLAYING BISPECIFIC ANTIBODY ON SURFACE OF MAMMALIAN C...
- Publication number 20230331871
- Publication date Oct 19, 2023
- DDBIO. CO, LTD., (SHANG HAI)
- Chen ZHOU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HIGHLY SPECIFIC CIRCULAR PROXIMITY LIGATION ASSAY
- Publication number 20230295691
- Publication date Sep 21, 2023
- The Board of Trustees of the Leland Stanford Junior University
- Henrik H.J. PERSSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T4 DNA Ligase Variants with Increased Thermostability
- Publication number 20230265412
- Publication date Aug 24, 2023
- AbClonal Science, Inc.
- Zhenyu Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HIGH PURITY gRNA SYNTHESIS PROCESS
- Publication number 20230220379
- Publication date Jul 13, 2023
- CRISPR Therapeutics AG
- Rajat Das
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ATP-DEPENDENT DNA LIGASE
- Publication number 20230125232
- Publication date Apr 27, 2023
- ArcticZymes AS
- Bernd Ketelsen Striberny
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Ribozyme-mediated RNA Assembly and Expression
- Publication number 20230073250
- Publication date Mar 9, 2023
- University of Rochester
- Douglas Matthew Anderson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREPARATION METHOD FOR DNA NEXT-GENERATION SEQUENCING LIBRARY
- Publication number 20230067708
- Publication date Mar 2, 2023
- DAAN GENE CO., LTD.
- ZHIKUN LIANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Nucleobase Editors
- Publication number 20230051661
- Publication date Feb 16, 2023
- Agency for Science, Technology and Research
- Liwei Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Ligases forming phosphoric ester bonds (6.5)

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Patents Grantslast 30 patents

Method for generating higher order genome editing libraries

Methods for assembling nucleic acids

Methods for identifying a location of an RNA in a biological sample

Increasing capture efficiency of spatial assays

Sample preparation methods, systems and compositions

T4 DNA ligase variants with increased thermostability

Methods for identifying a location of an RNA in a biological sample

Method for attaching one or more polynucleotide binding proteins to...

T4 DNA ligase variants with increased resistance to salt

Enzymatic ligation of nucleic acids

In vitro recombination method

Highly specific circular proximity ligation assay

Enhanced adaptor ligation

Sample preparation methods, systems and compositions

Particles coated with catalysts useful for splicing nucleic acids

Multiple ligase compositions, systems, and methods

Method to alter Chinese hamster ovary cell line stability

Method of preparing cell free nucleic acid molecules by in situ amp...

Double-strand DNA break quantification method

DNA ligase variants

Molecular detection using ligation amplification

Method for establishing eukaryotic expression cell line of CD36 mut...

Sample preparation methods, systems and compositions

Construction of next generation sequencing (NGS) libraries using co...

Processes for the production of oligonucleotides

Low sequence bias single-stranded DNA ligation

Multiple ligase compositions, systems, and methods

Ligase activity

Ligase activity

In vitro recombination method

Patents Applicationslast 30 patents

T7 DNA Ligase Variants R129D with Increased Specificity for Cohesiv...

CIRCULAR GUIDE RNAs FOR CRISPR/CAS EDITING SYSTEMS

METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID

ENGINEERED DNA LIGASE VARIANTS

TARGETED RNA EDITING BY LEVERAGING ENDOGENOUS ADAR USING ENGINEERED...

METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE

SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS

NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES

Methods for Assembling Nucleic Acids

MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF

T7 DNA Ligase Variants Having Increased Ligation Efficiency

MATERIAL AND METHOD FOR PREPARATION OF SMALL, SINGLE-STRANDED DNA C...

ENGINEERED RNA LIGASE VARIANTS

COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE-FREE ENZYMATIC SYNTHES...

NUCLEIC ACID PROCESSING VIA CIRCULARIZATION

INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS

Methods of Library Preparation

METHODS OF ENZYMATICALLY REPAIRING CLEAVED RNAS AND DETECTING THEREOF

T4 DNA Ligase Variants with Increased Resistance to Salt

METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO...

HIGH-SPEED PHOTO-CROSS-LINKING LINKER FOR MOLECULAR INTERACTION ANA...

METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE

METHOD FOR DISPLAYING BISPECIFIC ANTIBODY ON SURFACE OF MAMMALIAN C...

HIGHLY SPECIFIC CIRCULAR PROXIMITY LIGATION ASSAY

T4 DNA Ligase Variants with Increased Thermostability

HIGH PURITY gRNA SYNTHESIS PROCESS

ATP-DEPENDENT DNA LIGASE

Ribozyme-mediated RNA Assembly and Expression

PREPARATION METHOD FOR DNA NEXT-GENERATION SEQUENCING LIBRARY

Nucleobase Editors