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Lipophilic moiety
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C12N2310/3515
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N2310/00
Structure or type of the nucleic acid
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C12N2310/3515
Lipophilic moiety
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Patents Grants
last 30 patents
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Patent Grant
BBB-crossing lipid ligand of hetero nucleic acid
Patent number
12,305,169
Issue date
May 20, 2025
National University Corporation Tokyo Medical and Dental University
Takanori Yokota
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Immunostimulatory compositions
Patent number
12,305,173
Issue date
May 20, 2025
Elanco Animal Health GmbH
Thomas Ilg
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Asialoglycoprotein Receptor mediated delivery of therapeutically ac...
Patent number
12,290,567
Issue date
May 6, 2025
Arcturus Therapeutics, Inc.
Kumar Rajappan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating apolipoprotein (a) expression
Patent number
12,291,709
Issue date
May 6, 2025
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligomers and oligomer conjugates
Patent number
12,281,307
Issue date
Apr 22, 2025
HOFFMANN-LA ROCHE INC.
Hassan Javanbakht
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Conjugated antisense compounds and their use
Patent number
12,275,940
Issue date
Apr 15, 2025
Ionis Pharmaceuticals, Inc.
Michael Oestergaard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods of treating muscle atrophy and myotonic dy...
Patent number
12,263,224
Issue date
Apr 1, 2025
AVIDITY BIOSCIENCES, INC.
Andrew John Geall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for delivery of biomacromolecule agents
Patent number
12,257,352
Issue date
Mar 25, 2025
The Regents of the University of Michigan
James J. Moon
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for PRNP modulation
Patent number
12,258,566
Issue date
Mar 25, 2025
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified oligonucleotides
Patent number
12,258,563
Issue date
Mar 25, 2025
EMPIRICO INC.
Darren H. Wakefield
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Ribonucleic acids with 4′-thio-modified nucleotides and related met...
Patent number
12,247,046
Issue date
Mar 11, 2025
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid-polypeptide compositions and uses thereof
Patent number
12,234,290
Issue date
Feb 25, 2025
AVIDITY BIOSCIENCES, INC.
Andrew John Geall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting expression of transthyretin
Patent number
12,227,744
Issue date
Feb 18, 2025
Alnylam Pharmaceuticals, Inc.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Conjugation of lipophilic albumin-binding moiety to RNA for improve...
Patent number
12,201,644
Issue date
Jan 21, 2025
Vanderbilt University
Craig L. Duvall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid and other compositions and methods for the modulation...
Patent number
12,195,753
Issue date
Jan 14, 2025
The Board of Trustees of the University of Illinois
Aleksei Aksimentiev
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
Patent number
12,188,017
Issue date
Jan 7, 2025
Arrowhead Pharmaceuticals, Inc.
Christine I Wooddell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oversubscription scheduling
Patent number
12,180,475
Issue date
Dec 31, 2024
Nutanix, Inc.
Connor Patric Doyle
G06 - COMPUTING CALCULATING COUNTING
Information
Patent Grant
Dynamic pharmacokinetic-modifying anchors
Patent number
12,180,477
Issue date
Dec 31, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fully stabilized asymmetric siRNA
Patent number
12,173,286
Issue date
Dec 24, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Non-liposomal systems for nucleic acid delivery
Patent number
12,129,467
Issue date
Oct 29, 2024
ARBUTUS BIOPHARMA CORPORATION
Ed Yaworski
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Targeting ligands for therapeutic compounds
Patent number
12,116,573
Issue date
Oct 15, 2024
Arrowhead Pharmaceuticals, Inc.
David B. Rozema
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid-pegylated compounds, preparations and uses thereof
Patent number
12,098,371
Issue date
Sep 24, 2024
Hongene Biotech Corporation
Mufa Zou
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Xanthine dehydrogenase (XDH) iRNA compositions and methods of use t...
Patent number
12,091,666
Issue date
Sep 17, 2024
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating PNPLA3 expression
Patent number
12,084,662
Issue date
Sep 10, 2024
Dicerna Pharmaceuticals, Inc.
Utsav Saxena
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Bioactive conjugates for oligonucleotide delivery
Patent number
12,077,755
Issue date
Sep 3, 2024
University of Massachusetts
Anastasia Khvorova
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligonucleotides for SARS-CoV-2 modulation
Patent number
12,077,758
Issue date
Sep 3, 2024
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Agents for improved delivery of nucleic acids to eukaryotic cells
Patent number
12,065,665
Issue date
Aug 20, 2024
Molecular Transfer, Inc.
Joel Jessee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Transthyretin (TTR) iRNA compositions and methods of use thereof fo...
Patent number
12,049,628
Issue date
Jul 30, 2024
Alnylam Pharmaceuticals, Inc.
Tracy Zimmermann
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
12,042,541
Issue date
Jul 23, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Publication number
20250152726
Publication date
May 15, 2025
Avidity Biosciences, Inc.
Andrew John GEALL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS CONTAINING POLYNUCLEOTIDE AMPHIPHILES AND METHODS OF U...
Publication number
20250134992
Publication date
May 1, 2025
Elicio Therapeutics, Inc.
Peter C. DEMUTH
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTI-PTEN RNA INTERFERENCE OLIGONUCLEOTIDES AND USES THEREOF
Publication number
20250136992
Publication date
May 1, 2025
Nisim PERETS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAi OLIGONUCLEOTIDE CONJUGATES
Publication number
20250122500
Publication date
Apr 17, 2025
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TETRAMOLECULAR PARALLEL G-QUADRUPLEX-FORMING HYDROPHOBICALLY MODIFI...
Publication number
20250122496
Publication date
Apr 17, 2025
Inserm (institut National de la Sante et de la Recherche Medicale)
Philippe BARTHELEMY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONJUGATION OF LIPOPHILIC ALBUMIN-BINDING MOIETY TO RNA FOR IMPROVE...
Publication number
20250099497
Publication date
Mar 27, 2025
Vanderbilt University
Craig L. Duvall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DNA ORIGAMI STRUCTURE AND PROTEIN NANOPORE CONSTRUCT
Publication number
20250101415
Publication date
Mar 27, 2025
Illumina, Inc.
Miguel Angel Aleman Garcia
B82 - NANO-TECHNOLOGY
Information
Patent Application
COMPOSITIONS AND METHODS FOR SILENCING CARBONIC ANHYDRASE 2 EXPRESSION
Publication number
20250084418
Publication date
Mar 13, 2025
Alnylam Pharmaceuticals, Inc.
JEFFREY ZUBER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HEPARIN SULFATE BIOSYNTHESIS PATHWAY ENZYME IRNA AGENT COMPOSITIONS...
Publication number
20250084417
Publication date
Mar 13, 2025
Alnylam Pharmaceuticals, Inc.
Mangala Meenakshi Soundarapandian
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY AND M...
Publication number
20250075215
Publication date
Mar 6, 2025
Icahn School of Medicine at Mount Sinai
Anne SCHAEFER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FO...
Publication number
20250075211
Publication date
Mar 6, 2025
Alnylam Pharmaceuticals, Inc.
Tracy Zimmermann
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITION OF HAO1 (HYDROXYACID OXIDAS...
Publication number
20250064936
Publication date
Feb 27, 2025
Alnylam Pharmaceuticals, Inc.
William Querbes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DEGRADABLE LIPID COMPOUND FOR ACTIVE MOLECULE DELIVERY AND NANOCOMP...
Publication number
20250064940
Publication date
Feb 27, 2025
BEIJING CARRIUS BIO LTD.
Ming WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TUNABLE REVERSIR TM COMPOUNDS
Publication number
20250059536
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Ivan ZLATEV
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SGLT-2 TARGETING OLIGONUCLEOTIDES
Publication number
20250059539
Publication date
Feb 20, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY
Publication number
20250059533
Publication date
Feb 20, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051765
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE (HMGCR) IRNA COMPOSITIONS...
Publication number
20250043289
Publication date
Feb 6, 2025
Alnylam Pharmaceuticals, Inc.
Ho-Chou Tu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR SNCA MODULATION
Publication number
20250043284
Publication date
Feb 6, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
STEROL REGULATORY ELEMENT BINDING PROTEIN (SREBP) CHAPERONE (SCAP)...
Publication number
20250034570
Publication date
Jan 30, 2025
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY
Publication number
20250034571
Publication date
Jan 30, 2025
ARBUTUS BIOPHARMA CORPORATION
Ed Yaworski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID-PEGYLATED COMPOUNDS, PREPARATIONS AND USES THEREOF
Publication number
20250027091
Publication date
Jan 23, 2025
Hongene Biotech Corporation
Mufa Zou
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
LIPID-BASED CONJUGATES FOR SYSTEMIC, CENTRAL NERVOUS SYSTEM, PERIPH...
Publication number
20250018045
Publication date
Jan 16, 2025
Sanegene Bio USA Inc.
Weimin WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
POLYNUCLEOTIDE COMPOSITIONS, RELATED FORMULATIONS, AND METHODS OF U...
Publication number
20250019409
Publication date
Jan 16, 2025
ReCode Therapeutics, Inc.
Mirko Hennig
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE LECT2 GENE
Publication number
20250019699
Publication date
Jan 16, 2025
Alnylam Pharmaceuticals, Inc.
Gregory Hinkle
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HUNTINGTIN (HTT) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250011776
Publication date
Jan 9, 2025
Alnylam Pharmaceuticals, Inc.
William Cantley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AGENTS FOR IMPROVED DELIVERY OF NUCLEIC ACIDS TO EUKARYOTIC CELLS
Publication number
20250011815
Publication date
Jan 9, 2025
MOLECULAR TRANSFER, INC.
Joel Jessee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME
Publication number
20250011359
Publication date
Jan 9, 2025
Geron Corporation
Premchandran H. Ramiya
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
Publication number
20240424105
Publication date
Dec 26, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OLIGONUCLEOTIDES FOR SARS-CoV-2 MODULATION
Publication number
20240425860
Publication date
Dec 26, 2024
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...