Oligopeptidase A (3.4.24.70)

Industry

CPC
C12Y304/2407

This industry / category may be too specific. Please go to a parent level for more data

Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12YENZYMES C12Y304/00Hydrolases acting on peptide bonds

Current Industry

C12Y304/2407Oligopeptidase A (3.4.24.70)

Industries

Please log in for detailed analytics

Patents Grantslast 30 patents

Information Patent Grant
Deimmunized lysostaphin and methods of use
- Patent number 12,104,186
- Issue date Oct 1, 2024
- Insmed Incorporated
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Unglycosylated lysostaphin variant protein
- Patent number 12,049,653
- Issue date Jul 30, 2024
- Trustees of Dartmouth College
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multimodal antimicrobial therapy
- Patent number 11,717,561
- Issue date Aug 8, 2023
- Longhorn Vaccines & Diagnostics, LLC
- Gerald W. Fischer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Vasoconstrictive and antibacterial combination treatment for rosacea
- Patent number 11,439,693
- Issue date Sep 13, 2022
- MIGREOS HUMAN HEALTH B.V.
- Mark Leonard Offerhaus
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antimicrobial agents against Staphylococcus aureus
- Patent number 11,427,812
- Issue date Aug 30, 2022
- Lysando AG
- Manfred Biebl
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Pappalysin regulator
- Patent number 11,318,158
- Issue date May 3, 2022
- Aarhus Universitet
- Claus Oxvig
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Unglycosylated lysostaphin variant protein
- Patent number 11,155,801
- Issue date Oct 26, 2021
- Trustees of Dartmouth College
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for non-antibiotic treating of bacterial i...
- Patent number 11,149,269
- Issue date Oct 19, 2021
- New York University
- Richard Novick
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chimeric polypeptides and their use in bacterial decolonization
- Patent number 11,116,824
- Issue date Sep 14, 2021
- HYPHARM GMBH
- Holger Grallert
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Deimmunized lysostaphin and methods of use
- Patent number 11,091,749
- Issue date Aug 17, 2021
- Trustees of Dartmouth College
- Karl E. Griswold
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Targeting immunological functions to the site of bacterial infectio...
- Patent number 11,028,153
- Issue date Jun 8, 2021
- INTEGRATED BIOTHERAPEUTICS, INC.
- Mohammad Javad Aman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for detecting Staphylococcus contained in milk
- Patent number 10,732,179
- Issue date Aug 4, 2020
- Asahi Kasei Kabushiki Kaisha
- Koji Maehana
- G01 - MEASURING TESTING
Information Patent Grant
Method for detecting Staphylococcus contained in milk
- Patent number 10,527,616
- Issue date Jan 7, 2020
- Asahi Kasei Kabushiki Kaisha
- Koji Maehana
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeting immunological functions to the site of bacterial infectio...
- Patent number 10,487,140
- Issue date Nov 26, 2019
- INTEGRATED BIOTHERAPEUTICS, INC.
- Mohammad Javad Aman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Deimmunized lysostaphin and methods of use
- Patent number 10,358,636
- Issue date Jul 23, 2019
- STEALTH BIOLOGICS, LLC
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric polypeptides and their use in bacterial decolonization
- Patent number 10,342,857
- Issue date Jul 9, 2019
- HYpharm GmbH
- Holger Grallert
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for detecting Staphylococcus contained in milk
- Patent number 10,151,751
- Issue date Dec 11, 2018
- Asahi Kasei Kabushiki Kaisha
- Koji Maehana
- G01 - MEASURING TESTING
Information Patent Grant
Chimeric polypeptides and their use in bacterial decolonization
- Patent number 10,022,430
- Issue date Jul 17, 2018
- HYpharm GmbH
- Holger Grallert
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Enhanced staphylolytic activity of the Staphylococcus aureus bacter...
- Patent number 9,868,943
- Issue date Jan 16, 2018
- The United States of America, as represented by the Secretary of Agriculture
- David M. Donovan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multimodal antimicrobial therapy
- Patent number 9,814,766
- Issue date Nov 14, 2017
- Longhorn Vaccines & Diagnostics, LLC
- Gerald W. Fischer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method of peptide hydrolysis, peptidase, the composition for use as...
- Patent number 9,487,771
- Issue date Nov 8, 2016
- MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ
- Izabela Sabala
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lys K endolysin is synergistic with lysostaphin against MRSA
- Patent number 8,568,714
- Issue date Oct 29, 2013
- The United States of America, as represented by the Secretary of Agriculture
- David M. Donovan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Screening and treatment methods using IGS5 enzymes of the metallopr...
- Patent number 8,389,284
- Issue date Mar 5, 2013
- Abbott Healthcare Products B.V.
- Willy Deleersnijder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for treatment of staphylococcal infection...
- Patent number 8,198,231
- Issue date Jun 12, 2012
- Nutrition 21, Inc.
- Michael Climo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Screening and treatment methods using IGS5 enzymes of the metallopr...
- Patent number 8,012,471
- Issue date Sep 6, 2011
- Abbott Healthcare Products B.V.
- Willy Deleersnijder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-microbial compositions comprising a cationic peptide and a gly...
- Patent number 7,943,128
- Issue date May 17, 2011
- The University Court of the University of St. Andrews
- Peter John Coote
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody to human enzymes of the metalloprotease family
- Patent number 7,312,321
- Issue date Dec 25, 2007
- Solvay Pharmaceuticals B.V.
- Willy Deleersnijder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human enzymes of the metalloprotease family
- Patent number 7,189,525
- Issue date Mar 13, 2007
- Solvay Pharmaceuticals B.V.
- Willy Deleersnijder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for treatment of staphylococcal infection...
- Patent number 7,122,514
- Issue date Oct 17, 2006
- Nutrition 21, Inc.
- Michael Climo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human enzymes of the metalloprotease family
- Patent number 7,083,965
- Issue date Aug 1, 2006
- Solvay Pharmaceuticals B.V.
- Willy Deleersnijder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
CORYNEBACTERIUM TO TREAT OR LIMIT CUTANEOUS WOUND INFECTION
- Publication number 20250073280
- Publication date Mar 6, 2025
- Massachusetts Institute of Technology
- Tami Danielle LIEBERMAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN
- Publication number 20250059526
- Publication date Feb 20, 2025
- Trustees of Dartmouth College
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT POLYPEPTIDE FOR USE AS A MEDICINE, ANTISEPTIC AGENT, AN...
- Publication number 20240409910
- Publication date Dec 12, 2024
- MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE
- Izabela SABALA
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
BACTERIOLYSIS METHOD AND BACTERIA DETECTION METHOD
- Publication number 20240392231
- Publication date Nov 28, 2024
- Asahi Kasei Kabushiki Kaisha
- Katsuyoshi TAKAHASHI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LYSOSTAPHIN VARIANTS AND METHODS OF USE THEREOF
- Publication number 20240392275
- Publication date Nov 28, 2024
- BiomEdit, LLC
- Yong-Fu LI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Genetically Modified Mycoplasma Bacteria Active Against Heterogenou...
- Publication number 20240382537
- Publication date Nov 21, 2024
- FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA
- Rocco Mazzolini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods for Lysis of Cells Within a Sample
- Publication number 20230365960
- Publication date Nov 16, 2023
- MicrobeDX, Inc.
- Gabriel MONTI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PROTEINS FOR SELECTIVE LYSIS OF BACTERIA
- Publication number 20220378884
- Publication date Dec 1, 2022
- Bactoclear Holdings Pte. Ltd.
- Anisha Ambady
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VIRAL MEDIATED GENE DELIVERY FOR TRANSIENT EXPRESSION OF PROTEINS
- Publication number 20220348960
- Publication date Nov 3, 2022
- Regents of the University of Minnesota
- Christopher Stach
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN
- Publication number 20220213460
- Publication date Jul 7, 2022
- Trustees of Dartmouth College
- Karl E. Griswold
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR NON-ANTIBIOTIC TREATING OF BACTERIAL I...
- Publication number 20220033801
- Publication date Feb 3, 2022
- NEW YORK UNIVERSITY
- Richard NOVICK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BLOOD COMPONENT POTENTIATION OF LYTIC PROTEIN ANTI-BACTERIAL ACTIVI...
- Publication number 20220023399
- Publication date Jan 27, 2022
- Contrafect Corporation
- Raymond Schuch
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
- Publication number 20210395713
- Publication date Dec 23, 2021
- Trustees of Dartmouth College
- Karl E. GRISWOLD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FIBRINOLYTIC ENZYME FROM AGROCYBE AEGERITA AND A PREPARATION METHOD...
- Publication number 20210062175
- Publication date Mar 4, 2021
- XIAOLAN LIU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods for Lysis of Cells Within a Sample
- Publication number 20200370036
- Publication date Nov 26, 2020
- MicrobeDX, Inc.
- Gabriel MONTI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Pappalysin regulator
- Publication number 20200261490
- Publication date Aug 20, 2020
- AARHUS UNIVERSITET
- Claus OXVIG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Targeting Immunological Functions to the Site of Bacterial Infectio...
- Publication number 20200216521
- Publication date Jul 9, 2020
- INTEGRATED BIOTHERAPEUTICS, INC.
- Mohammad Javad AMAN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR NON-ANTIBIOTIC TREATING OF BACTERIAL I...
- Publication number 20200199570
- Publication date Jun 25, 2020
- NEW YORK UNIVERSITY
- Richard NOVICK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
- Publication number 20200040321
- Publication date Feb 6, 2020
- Trustees of Dartmouth College
- Karl E. GRISWOLD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Chimeric Polypeptides and Their Use in Bacterial Decolonization
- Publication number 20190381151
- Publication date Dec 19, 2019
- HYPHARM GMBH
- Holger Grallert
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NEW ANTIMICROBIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS
- Publication number 20190359962
- Publication date Nov 28, 2019
- LYSANDO AG
- Manfred BIEBL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK
- Publication number 20190079089
- Publication date Mar 14, 2019
- Asahi Kasei Kabushiki Kaisha
- Koji MAEHANA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK
- Publication number 20190049446
- Publication date Feb 14, 2019
- Asahi Kasei Kabushiki Kaisha
- Koji MAEHANA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Chimeric Polypeptides and Their Use in Bacterial Decolonization
- Publication number 20180333471
- Publication date Nov 22, 2018
- HYPHARM GMBH
- Holger Grallert
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Multimodal Antimicrobial Therapy
- Publication number 20180042999
- Publication date Feb 15, 2018
- Longhorn Vaccines and Diagnostics, LLC
- Gerald W. Fischer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE
- Publication number 20170145398
- Publication date May 25, 2017
- Trustees of Dartmouth College
- Karl E. GRISWOLD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TARGETING IMMUNOLOGICAL FUNCTIONS TO THE SITE OF BACTERIAL INFECTIO...
- Publication number 20160333077
- Publication date Nov 17, 2016
- Integrated BioTherapeutics, Inc.
- Mohammad Javad AMAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK
- Publication number 20160313327
- Publication date Oct 27, 2016
- Asahi Kasei Kabushiki Kaisha
- Koji MAEHANA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN
- Publication number 20160168556
- Publication date Jun 16, 2016
- Trustees of Dartmouth College
- Karl E. Griswold
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Pappalysin Regulator
- Publication number 20160151405
- Publication date Jun 2, 2016
- AARHUS UNIVERSITET
- Claus OXVIG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Oligopeptidase A (3.4.24.70)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Deimmunized lysostaphin and methods of use

Unglycosylated lysostaphin variant protein

Multimodal antimicrobial therapy

Vasoconstrictive and antibacterial combination treatment for rosacea

Antimicrobial agents against Staphylococcus aureus

Pappalysin regulator

Unglycosylated lysostaphin variant protein

Compositions and methods for non-antibiotic treating of bacterial i...

Chimeric polypeptides and their use in bacterial decolonization

Deimmunized lysostaphin and methods of use

Targeting immunological functions to the site of bacterial infectio...

Method for detecting Staphylococcus contained in milk

Method for detecting Staphylococcus contained in milk

Targeting immunological functions to the site of bacterial infectio...

Deimmunized lysostaphin and methods of use

Chimeric polypeptides and their use in bacterial decolonization

Method for detecting Staphylococcus contained in milk

Chimeric polypeptides and their use in bacterial decolonization

Enhanced staphylolytic activity of the Staphylococcus aureus bacter...

Multimodal antimicrobial therapy

Method of peptide hydrolysis, peptidase, the composition for use as...

Lys K endolysin is synergistic with lysostaphin against MRSA

Screening and treatment methods using IGS5 enzymes of the metallopr...

Compositions and methods for treatment of staphylococcal infection...

Screening and treatment methods using IGS5 enzymes of the metallopr...

Anti-microbial compositions comprising a cationic peptide and a gly...

Antibody to human enzymes of the metalloprotease family

Human enzymes of the metalloprotease family

Compositions and methods for treatment of staphylococcal infection...

Human enzymes of the metalloprotease family

Patents Applicationslast 30 patents

CORYNEBACTERIUM TO TREAT OR LIMIT CUTANEOUS WOUND INFECTION

UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN

RECOMBINANT POLYPEPTIDE FOR USE AS A MEDICINE, ANTISEPTIC AGENT, AN...

BACTERIOLYSIS METHOD AND BACTERIA DETECTION METHOD

LYSOSTAPHIN VARIANTS AND METHODS OF USE THEREOF

Genetically Modified Mycoplasma Bacteria Active Against Heterogenou...

Methods for Lysis of Cells Within a Sample

CHIMERIC PROTEINS FOR SELECTIVE LYSIS OF BACTERIA

VIRAL MEDIATED GENE DELIVERY FOR TRANSIENT EXPRESSION OF PROTEINS

UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN

COMPOSITIONS AND METHODS FOR NON-ANTIBIOTIC TREATING OF BACTERIAL I...

BLOOD COMPONENT POTENTIATION OF LYTIC PROTEIN ANTI-BACTERIAL ACTIVI...

DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE

FIBRINOLYTIC ENZYME FROM AGROCYBE AEGERITA AND A PREPARATION METHOD...

Methods for Lysis of Cells Within a Sample

Pappalysin regulator

Targeting Immunological Functions to the Site of Bacterial Infectio...

COMPOSITIONS AND METHODS FOR NON-ANTIBIOTIC TREATING OF BACTERIAL I...

DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE

Chimeric Polypeptides and Their Use in Bacterial Decolonization

NEW ANTIMICROBIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS

METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK

METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK

Chimeric Polypeptides and Their Use in Bacterial Decolonization

Multimodal Antimicrobial Therapy

DEIMMUNIZED LYSOSTAPHIN AND METHODS OF USE

TARGETING IMMUNOLOGICAL FUNCTIONS TO THE SITE OF BACTERIAL INFECTIO...

METHOD FOR DETECTING STAPHYLOCOCCUS CONTAINED IN MILK

UNGLYCOSYLATED LYSOSTAPHIN VARIANT PROTEIN

Pappalysin Regulator