Ornithine carbamoyltransferase (2.1.3.3)

Industry

CPC
C12Y201/03003

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12YENZYMES C12Y201/00Transferases transferring one-carbon groups (2.1)

Current Industry

C12Y201/03003Ornithine carbamoyltransferase (2.1.3.3)

Industries

Patents Grantslast 30 patents

Information Patent Grant
Cleavable lipids
- Patent number 12,102,720
- Issue date Oct 1, 2024
- Translate Bio, Inc.
- Braydon Charles Guild
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods for purification of messenger RNA
- Patent number 11,976,272
- Issue date May 7, 2024
- Translate Bio, Inc.
- Jonathan Abysalh
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Cationic polymers
- Patent number 11,975,110
- Issue date May 7, 2024
- Translate Bio, Inc.
- Frank DeRosa
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Arginine supplementation to improve efficiency in gas fermenting ac...
- Patent number 11,965,201
- Issue date Apr 23, 2024
- LanzaTech NZ, Inc.
- Kaspar Valgepea
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Polynucleotides and vectors for the expression of transgenes
- Patent number 11,938,197
- Issue date Mar 26, 2024
- THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD (INCORPORATING...
- Ian Alexander
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Polynucleotides encoding ornithine transcarbamylase for the treatme...
- Patent number 11,859,215
- Issue date Jan 2, 2024
- ModernaTX, Inc.
- Zhijian Zhuo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions useful in treatment of ornithine transcarbamylase (OTC...
- Patent number 11,732,246
- Issue date Aug 22, 2023
- The Trustees of the University of Pennsylvania
- Lili Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for treating ornithine transcarbamylase de...
- Patent number 11,685,906
- Issue date Jun 27, 2023
- Arcturus Therapeutics, Inc.
- Carlos G. Perez-Garcia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Subcutaneous delivery of messenger RNA
- Patent number 11,400,109
- Issue date Aug 2, 2022
- Translate Bio, Inc.
- Shrirang Karve
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Adeno-associated virus (AAV) serotype 8 sequences, vectors containi...
- Patent number 11,396,663
- Issue date Jul 26, 2022
- The Trustees of the University of Pennsylvania
- Guangping Gao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Adeno-associated virus (AAV) serotype 8 sequences, vectors containi...
- Patent number 11,390,883
- Issue date Jul 19, 2022
- The Trustees of the University of Pennsylvania
- Guangping Gao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Microorganism for producing ornithine and process for producing orn...
- Patent number 11,365,400
- Issue date Jun 21, 2022
- CJ Cheiljedang Corporation
- Su Jin Park
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Stable gene transfer to proliferating cells
- Patent number 11,351,272
- Issue date Jun 7, 2022
- THE SYDNEYCHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD) (INCORPORATING...
- Ian Alexander
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Microorganisms for producing putrescine or ornithine and process fo...
- Patent number 11,268,074
- Issue date Mar 8, 2022
- CJ Cheiljedang Corporation
- Su Jin Park
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Disease model pig exhibiting stable phenotype, and production metho...
- Patent number 11,246,299
- Issue date Feb 15, 2022
- PORMEDTEC CO., LTD.
- Hiroshi Nagashima
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Cleavable lipids
- Patent number 11,234,936
- Issue date Feb 1, 2022
- Translate Bio, Inc.
- Braydon Charles Guild
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Composition and methods for treatment of ornithine transcarbamylase...
- Patent number 11,167,043
- Issue date Nov 9, 2021
- Translate Bio, Inc.
- Kim Askew
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
MRNA for use in treatment of human genetic diseases
- Patent number 11,135,274
- Issue date Oct 5, 2021
- Translate Bio, Inc.
- Braydon Charles Guild
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multimeric coding nucleic acid and uses thereof
- Patent number 11,124,804
- Issue date Sep 21, 2021
- Translate Bio, Inc.
- Frank DeRosa
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Ornithine transcarbamylase coding polyribonucleotides and formulati...
- Patent number 11,104,887
- Issue date Aug 31, 2021
- ethris GmbH
- Carsten Rudolph
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Microorganisms having putrescine productivity and process for produ...
- Patent number 11,053,524
- Issue date Jul 6, 2021
- CJ Cheiljedang Corporation
- Kyoung Min Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Microorganisms for producing putrescine or ornithine and process fo...
- Patent number 11,053,525
- Issue date Jul 6, 2021
- CJ Cheiljedang Corporation
- Hee Kyoung Jung
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Arginine supplementation to improve efficiency in gas fermenting ac...
- Patent number 10,995,347
- Issue date May 4, 2021
- LANZATECH NEW ZEALAND LIMITED
- Michael Koepke
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for purification of messenger RNA
- Patent number 10,975,369
- Issue date Apr 13, 2021
- Translate Bio, Inc.
- Frank DeRosa
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Messenger RNA therapy for the treatment of ornithine transcarbamyla...
- Patent number 10,835,583
- Issue date Nov 17, 2020
- Translate Bio, Inc.
- Frank DeRosa
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Messenger UNA molecules and uses thereof
- Patent number 10,815,463
- Issue date Oct 27, 2020
- Arcturus Therapeutics, Inc.
- Padmanabh Chivukula
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for purification of messenger RNA
- Patent number 10,808,241
- Issue date Oct 20, 2020
- Translate Bio, Inc.
- Jonathan Abysalh
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Compositions useful in treatment of ornithine transcarbamylase (OTC...
- Patent number 10,781,430
- Issue date Sep 22, 2020
- The Trustees of the University of Pennsylvania
- Lili Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cleavable lipids
- Patent number 10,702,478
- Issue date Jul 7, 2020
- Translate Bio, Inc.
- Braydon Charles Guild
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions useful in treatment of ornithine transcarbamylase (OTC...
- Patent number 10,626,382
- Issue date Apr 21, 2020
- The Trustees of the University of Pennsylvania
- Lili Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
COMPOSITION AND METHODS INCLUDING RECOMBINANT VIRUSES MODULATING AR...
- Publication number 20240316130
- Publication date Sep 26, 2024
- UNM Rainforest Innovations
- Eric Bartee
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATME...
- Publication number 20240247239
- Publication date Jul 25, 2024
- Moderna TX, Inc.
- Zhijian Zhuo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LIPID NANOPARTICLES AND POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCAR...
- Publication number 20240189449
- Publication date Jun 13, 2024
- ModernaTX, Inc.
- Kerry Benenato
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS
- Publication number 20240189446
- Publication date Jun 13, 2024
- Poseida Therapeutics, Inc.
- Joshua RYCHAK
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Process of Preparing mRNA-Loaded Lipid Nanoparticles
- Publication number 20240041789
- Publication date Feb 8, 2024
- Translate Bio, Inc.
- Shrirang Karve
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DE...
- Publication number 20240002815
- Publication date Jan 4, 2024
- Arcturus Therapeutics, Inc.
- Carlos G. PEREZ-GARCIA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS USEFUL IN TREATMENT OF ORNITHINE TRANSCARBAMYLASE (OTC...
- Publication number 20230416700
- Publication date Dec 28, 2023
- The Trustees of the University of Pennsylvania
- Lili Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC LIVER DISOR...
- Publication number 20230104091
- Publication date Apr 6, 2023
- Poseida Therapeutics, Inc.
- Jingjing JIANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SUBCUTANEOUS DELIVERY OF MESSENGER RNA
- Publication number 20230065040
- Publication date Mar 2, 2023
- Translate Bio, Inc.
- Shrirang Karve
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ORNITHINE TRANSCARBAMYLASE (OTC) CONSTRUCTS AND METHODS OF USING TH...
- Publication number 20230001021
- Publication date Jan 5, 2023
- GENEVANT SCIENCES GMBH
- Owen DALY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF
- Publication number 20220073944
- Publication date Mar 10, 2022
- Translate Bio, Inc.
- Frank DeRosa
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Composition and Methods for Treatment of Ornithine Transcarbamylase...
- Publication number 20220072152
- Publication date Mar 10, 2022
- Translate Bio, Inc.
- Kim Askew
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES
- Publication number 20220054602
- Publication date Feb 24, 2022
- Translate Bio, Inc.
- Braydon Charles Guild
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ADENO-ASSOCIATED VIRUS (AAV) SEROTYPE 8 SEQUENCES, VECTORS CONTAINI...
- Publication number 20220025399
- Publication date Jan 27, 2022
- The Trustees of the University of Pennsylvania
- Guangping Gao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAM...
- Publication number 20210284974
- Publication date Sep 16, 2021
- Arcturus Therapeutics, Inc.
- Padmanabh Chivukula
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ARGININE SUPPLEMENTATION TO IMPROVE EFFICIENCY IN GAS FERMENTING AC...
- Publication number 20210230648
- Publication date Jul 29, 2021
- LanzaTech New Zealand Limited
- Kaspar Valgepea
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Application
MESSENGER RNA THERAPY FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLA...
- Publication number 20210205421
- Publication date Jul 8, 2021
- Translate Bio, Inc.
- Frank DeRosa
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Methods For Purification of Messenger RNA
- Publication number 20210180041
- Publication date Jun 17, 2021
- Translate Bio, Inc.
- Frank DeRosa
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Methods For Purification of Messenger RNA
- Publication number 20210123041
- Publication date Apr 29, 2021
- Translate Bio, Inc.
- Jonathan Abysalh
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
Cationic Polymers
- Publication number 20210113483
- Publication date Apr 22, 2021
- Translate Bio, Inc.
- Frank DeRosa
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR FACILITATING DELIVERY OF SYNTHETIC NUC...
- Publication number 20210052706
- Publication date Feb 25, 2021
- Translate Bio MA, Inc.
- Balkrishen Bhat
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MICROORGANISM FOR PRODUCING PUTRESCINE OR ORNITHINE AND PROCESS FOR...
- Publication number 20210054347
- Publication date Feb 25, 2021
- CJ CHEILJEDANG CORPORATION
- Su Jin PARK
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS USEFUL IN TREATMENT OF ORNITHINE TRANSCARBAMYLASE (OTC...
- Publication number 20200377866
- Publication date Dec 3, 2020
- The Trustees of the University of Pennsylvania
- Lili Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSION PROTEINS
- Publication number 20200308557
- Publication date Oct 1, 2020
- CANCER RESEARCH TECHNOLOGY LIMITED
- Francis Jay Mussai
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ORNITHINE TRANSCARBAMYLASE CODING POLYRIBONUCLEOTIDES AND FORMULATI...
- Publication number 20200308556
- Publication date Oct 1, 2020
- Ethris GmbH
- Carsten Rudolph
- C07 - ORGANIC CHEMISTRY
Information Patent Application
POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATME...
- Publication number 20200299652
- Publication date Sep 24, 2020
- ModernaTX, Inc.
- Zhijian Zhuo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DE...
- Publication number 20200181584
- Publication date Jun 11, 2020
- Arcturus Therapeutics, Inc.
- Carlos G. PEREZ-GARCIA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF
- Publication number 20200172923
- Publication date Jun 4, 2020
- Translate Bio, Inc.
- Frank DeRosa
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
STABLE GENE TRANSFER TO PROLIFERATING CELLS
- Publication number 20200016278
- Publication date Jan 16, 2020
- THE SYDNEY CHILDREN'S HOSPITALS NETWORK (RANDWICK AND WESTMEAD) (INCORPORATIN...
- Ian Alexander
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
POLYNUCLEOTIDES AND VECTORS FOR THE EXPRESSION OF TRANSGENES
- Publication number 20190365926
- Publication date Dec 5, 2019
- Children's Medical Research Institute
- Ian ALEXANDER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Ornithine carbamoyltransferase (2.1.3.3)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Cleavable lipids

Methods for purification of messenger RNA

Cationic polymers

Arginine supplementation to improve efficiency in gas fermenting ac...

Polynucleotides and vectors for the expression of transgenes

Polynucleotides encoding ornithine transcarbamylase for the treatme...

Compositions useful in treatment of ornithine transcarbamylase (OTC...

Compositions and methods for treating ornithine transcarbamylase de...

Subcutaneous delivery of messenger RNA

Adeno-associated virus (AAV) serotype 8 sequences, vectors containi...

Adeno-associated virus (AAV) serotype 8 sequences, vectors containi...

Microorganism for producing ornithine and process for producing orn...

Stable gene transfer to proliferating cells

Microorganisms for producing putrescine or ornithine and process fo...

Disease model pig exhibiting stable phenotype, and production metho...

Cleavable lipids

Composition and methods for treatment of ornithine transcarbamylase...

MRNA for use in treatment of human genetic diseases

Multimeric coding nucleic acid and uses thereof

Ornithine transcarbamylase coding polyribonucleotides and formulati...

Microorganisms having putrescine productivity and process for produ...

Microorganisms for producing putrescine or ornithine and process fo...

Arginine supplementation to improve efficiency in gas fermenting ac...

Methods for purification of messenger RNA

Messenger RNA therapy for the treatment of ornithine transcarbamyla...

Messenger UNA molecules and uses thereof

Methods for purification of messenger RNA

Compositions useful in treatment of ornithine transcarbamylase (OTC...

Cleavable lipids

Compositions useful in treatment of ornithine transcarbamylase (OTC...

Patents Applicationslast 30 patents

COMPOSITION AND METHODS INCLUDING RECOMBINANT VIRUSES MODULATING AR...

POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATME...

LIPID NANOPARTICLES AND POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCAR...

COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS

Process of Preparing mRNA-Loaded Lipid Nanoparticles

COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DE...

COMPOSITIONS USEFUL IN TREATMENT OF ORNITHINE TRANSCARBAMYLASE (OTC...

COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC LIVER DISOR...

SUBCUTANEOUS DELIVERY OF MESSENGER RNA

ORNITHINE TRANSCARBAMYLASE (OTC) CONSTRUCTS AND METHODS OF USING TH...

MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF

Composition and Methods for Treatment of Ornithine Transcarbamylase...

mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES

ADENO-ASSOCIATED VIRUS (AAV) SEROTYPE 8 SEQUENCES, VECTORS CONTAINI...

COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAM...

ARGININE SUPPLEMENTATION TO IMPROVE EFFICIENCY IN GAS FERMENTING AC...

MESSENGER RNA THERAPY FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLA...

Methods For Purification of Messenger RNA

Methods For Purification of Messenger RNA

Cationic Polymers

COMPOSITIONS AND METHODS FOR FACILITATING DELIVERY OF SYNTHETIC NUC...

MICROORGANISM FOR PRODUCING PUTRESCINE OR ORNITHINE AND PROCESS FOR...

COMPOSITIONS USEFUL IN TREATMENT OF ORNITHINE TRANSCARBAMYLASE (OTC...

FUSION PROTEINS

ORNITHINE TRANSCARBAMYLASE CODING POLYRIBONUCLEOTIDES AND FORMULATI...

POLYNUCLEOTIDES ENCODING ORNITHINE TRANSCARBAMYLASE FOR THE TREATME...

COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DE...

MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF

STABLE GENE TRANSFER TO PROLIFERATING CELLS

POLYNUCLEOTIDES AND VECTORS FOR THE EXPRESSION OF TRANSGENES