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Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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C12N15/1082
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
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C12N15/1082
Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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Patents Grants
last 30 patents
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Patent Grant
Methods of screening using barcoded libraries
Patent number
12,157,885
Issue date
Dec 3, 2024
President and Fellows of Harvard College
Christian Schroeder Kaas
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Methods and compositions for modulating a genome
Patent number
12,123,034
Issue date
Oct 22, 2024
FLAGSHIP PIONEERING INNOVATIONS VI, LLC
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA vectors, transposons and transposases for eukaryotic genome mod...
Patent number
12,122,995
Issue date
Oct 22, 2024
DNA TWOPOINTO INC.
Jeremy Minshull
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for genomic integration of nucleic acids i...
Patent number
12,110,498
Issue date
Oct 8, 2024
Amyris, Inc.
Kevin George
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cofactor self-sufficient Escherichia coli and construction method a...
Patent number
12,104,191
Issue date
Oct 1, 2024
Zhejiang University of Technology
Yaping Xue
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for using transcription-dependent directed evolution of AAV...
Patent number
12,084,654
Issue date
Sep 10, 2024
Oregon Health & Science University
Hiroyuki Nakai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for using transcription-dependent directed evolution of AAV...
Patent number
12,084,653
Issue date
Sep 10, 2024
Oregon Health & Science University
Hiroyuki Nakai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fast-track humanisation of specific binding molecules
Patent number
12,077,882
Issue date
Sep 3, 2024
ELASMOGEN LTD
Caroline Jane Barelle
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
HIV vaccines and methods of using
Patent number
12,053,517
Issue date
Aug 6, 2024
Gilead Sciences, Inc.
Jiani Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA vectors, transposons and transposases for eukaryotic genome mod...
Patent number
12,054,702
Issue date
Aug 6, 2024
DNA TWOPOINTO INC.
Jeremy Minshull
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
AAV vectors
Patent number
12,043,848
Issue date
Jul 23, 2024
Vigeneron GmbH
Stylianos Michalakis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for modulating a genome
Patent number
12,037,617
Issue date
Jul 16, 2024
FLAGSHIP PIONEERING INNOVATIONS VI, LLC
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating a genome
Patent number
12,031,162
Issue date
Jul 9, 2024
FLAGSHIP PIONEERING INNOVATIONS VI, LLC
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating a genome
Patent number
12,024,728
Issue date
Jul 2, 2024
FLAGSHIP PIONEERING INNOVATIONS VI, LLC
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Delivery and use of the CRISPR-CAS systems, vectors and composition...
Patent number
12,018,275
Issue date
Jun 25, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified peptide display
Patent number
12,012,593
Issue date
Jun 18, 2024
Miti Biosystems GmbH
Guntram Christiansen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Linking sequence reads using paired code tags
Patent number
11,993,772
Issue date
May 28, 2024
Illumina, Inc.
Frank J. Steemers
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for recovering two or more genes, or gene products, encoding...
Patent number
11,976,276
Issue date
May 7, 2024
Memo Therapeutics AG
Martin Held
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for measuring and improving CRISPR reagent function
Patent number
11,946,163
Issue date
Apr 2, 2024
KSQ Therapeutics, Inc.
Gregory V. Kryukov
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Modified immune cells having enhanced function and methods for scre...
Patent number
11,920,130
Issue date
Mar 5, 2024
The Trustees of the University of Pennsylvania
Yangbing Zhao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
High-throughput assembly of genetic elements
Patent number
11,898,141
Issue date
Feb 13, 2024
The Broad Institute, Inc.
Robert Nicol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Construction method of a tight regulation system for gene expressio...
Patent number
11,879,124
Issue date
Jan 23, 2024
HUBEI UNIVERSITY
Shihui Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Contiguity preserving transposition
Patent number
11,873,480
Issue date
Jan 16, 2024
ILLUMINA CAMBRIDGE LIMITED
Frank J. Steemers
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR/Cas screening platform to identify genetic modifiers of tau...
Patent number
11,845,931
Issue date
Dec 19, 2023
REGENERON PHARMACEUTICALS, INC.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, methods, modules and instruments for automated nuclei...
Patent number
11,845,932
Issue date
Dec 19, 2023
Inscripta, Inc.
Burak Dura
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mammalian cell line for protein production and library generation
Patent number
11,802,281
Issue date
Oct 31, 2023
ETH ZURICH
Sai Reddy
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
CRISPR enabled multiplexed genome engineering
Patent number
11,795,479
Issue date
Oct 24, 2023
The Regents of the University of Colorado
Andrew Garst
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
HIV vaccines and methods of making and using
Patent number
11,795,210
Issue date
Oct 24, 2023
Gilead Sciences, Inc.
Xinan Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR/Cas dropout screening platform to reveal genetic vulnerabili...
Patent number
11,781,131
Issue date
Oct 10, 2023
REGENERON PHARMACEUTICALS, INC.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA extraction method using microwave for next generation sequencin...
Patent number
11,781,132
Issue date
Oct 10, 2023
Macrogen, Inc.
Joshua Sungwoo Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
METHODS AND NUCLEIC ACID MOLECULES FOR AAV VECTOR SELECTION
Publication number
20240417717
Publication date
Dec 19, 2024
Children's Medical Research Institute
Adrian Westhaus
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Platform Using iPSC-Derived Cardiomyocytes Carrying Gene Variants a...
Publication number
20240401031
Publication date
Dec 5, 2024
SRI International
Paul OMAILLE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LINKING SEQUENCE READS USING PAIRED CODE TAGS
Publication number
20240384262
Publication date
Nov 21, 2024
Illumina, Inc.
Frank J. STEEMERS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FAST-TRACK HUMANISATION OF SPECIFIC BINDING MOLECULES
Publication number
20240376639
Publication date
Nov 14, 2024
ELASMOGEN LTD
Caroline Jane BARELLE
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
High-Throughput Cellular Molecular Function Assay System and Method
Publication number
20240347133
Publication date
Oct 17, 2024
Heligenics Inc.
Martin R. SCHILLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR IMPROVING T CELL PERSISTENCE AND FUNCTION
Publication number
20240327826
Publication date
Oct 3, 2024
The Board of Trustees of the Leland Stanford Junior University
Ansuman Satpathy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AAV Vectors
Publication number
20240318149
Publication date
Sep 26, 2024
VIGENERON GMBH
Stylianos MICHALAKIS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS
Publication number
20240309361
Publication date
Sep 19, 2024
bluebird bio, inc.
Ilya Shestopalov
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRANS-ACTIVATORS AND METHODS AND USE THEREOF
Publication number
20240309360
Publication date
Sep 19, 2024
The Governing Council of the University of Toronto
Mikko Joonas Oskari Taipale
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY
Publication number
20240301502
Publication date
Sep 12, 2024
Flagship Pioneering Innovations VI, LLC.
Anthony P. Shuber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY-ENGINEERED BACTERIAL STRAINS FOR IMPROVED FIXATION OF N...
Publication number
20240294953
Publication date
Sep 5, 2024
Pivot Bio, Inc.
Bilge Ozaydin Eskiyenenturk
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR CODON OPTIMIZATION AND USES THEREOF
Publication number
20240271122
Publication date
Aug 15, 2024
Opentrons LabWorks Inc.
Joel S. Bader
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AUTOMATED CELL PROCESSING METHODS, MODULES, INSTRUMENTS, AND SYSTEMS
Publication number
20240263170
Publication date
Aug 8, 2024
Inscripta, Inc.
Jorge Bernate
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING A GENOME
Publication number
20240247243
Publication date
Jul 25, 2024
Flagship Pioneering Innovations VI, LLC.
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMBINATORIAL VECTOR CLONING AND TRANSFECTION STRATEGIES FOR TARGET...
Publication number
20240240175
Publication date
Jul 18, 2024
Genentech, Inc.
Shahram Misaghi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY
Publication number
20240229151
Publication date
Jul 11, 2024
Flagship Pioneering Innovations VI, LLC.
Anthony P. Shuber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FO...
Publication number
20240209359
Publication date
Jun 27, 2024
THE BROAD INSTITUTE, INC.
Feng ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Linear DNA with Enhanced Resistance Against Exonucleases
Publication number
20240209362
Publication date
Jun 27, 2024
4BASEBIO, S.L.U.
Heikki Lanckriet
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MULTIPLEX GENOME ENGINEERING IN EUKARYOTES
Publication number
20240200056
Publication date
Jun 20, 2024
Yale University
Edward Barbieri
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
Methods of Library Preparation
Publication number
20240175010
Publication date
May 30, 2024
Illumina, Inc.
Allison Yunghans
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS FOR SATURATING MUTAGEN...
Publication number
20240167018
Publication date
May 23, 2024
THE BROAD INSTITUTE, INC.
Daniel E. Bauer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANALYZING EXPRESSION OF PROTEIN-CODING VARIANTS IN CELLS
Publication number
20240167020
Publication date
May 23, 2024
Illumina, Inc.
Hongxia Xu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENHANCED DIVERSIFYING BASE EDITORS FOR DIRECTED EVOLUTION
Publication number
20240167015
Publication date
May 23, 2024
Georgia Tech Research Corporation
John James Blazeck
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APTAMERS, CONTAINERS AND METHODS FOR CELL TRANSDUCTION
Publication number
20240167019
Publication date
May 23, 2024
SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION
Katie Campbell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED IMMUNE CELLS HAVIG ENHANCED FUNCTION AND METHODS FOR SCREE...
Publication number
20240167024
Publication date
May 23, 2024
The Trustees of the University of Pennsylvania
Yangbing Zhao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR MUTAGENESIS SCREENING IN MAMMALIAN CELLS
Publication number
20240141330
Publication date
May 2, 2024
The Board of Regents of the University of Texas System
Ralf KITTLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS, METHODS, MODULES AND INSTRUMENTS FOR AUTOMATED NUCLEI...
Publication number
20240141331
Publication date
May 2, 2024
Inscripta, Inc.
Burak Dura
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY
Publication number
20240132970
Publication date
Apr 25, 2024
Flagship Pioneering Innovations VI, LLC.
Anthony P. Shuber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IDENTIFICATION OF GENOMIC TARGETS
Publication number
20240124872
Publication date
Apr 18, 2024
UNIVERSITY OF LEEDS
Viktor Lukacs
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF CRISPR SYSTEMS AND CO...
Publication number
20240117382
Publication date
Apr 11, 2024
THE BROAD INSTITUTE, INC.
David Benjamin Turitz Cox
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...