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Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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C12N15/1082
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
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C12N15/1082
Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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Patents Grants
last 30 patents
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Patent Grant
Method for recovering two or more genes, or gene products, encoding...
Patent number
11,976,276
Issue date
May 7, 2024
Memo Therapeutics AG
Martin Held
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for measuring and improving CRISPR reagent function
Patent number
11,946,163
Issue date
Apr 2, 2024
KSQ Therapeutics, Inc.
Gregory V. Kryukov
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Modified immune cells having enhanced function and methods for scre...
Patent number
11,920,130
Issue date
Mar 5, 2024
The Trustees of the University of Pennsylvania
Yangbing Zhao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
High-throughput assembly of genetic elements
Patent number
11,898,141
Issue date
Feb 13, 2024
The Broad Institute, Inc.
Robert Nicol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Construction method of a tight regulation system for gene expressio...
Patent number
11,879,124
Issue date
Jan 23, 2024
HUBEI UNIVERSITY
Shihui Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Contiguity preserving transposition
Patent number
11,873,480
Issue date
Jan 16, 2024
ILLUMINA CAMBRIDGE LIMITED
Frank J. Steemers
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR/Cas screening platform to identify genetic modifiers of tau...
Patent number
11,845,931
Issue date
Dec 19, 2023
REGENERON PHARMACEUTICALS, INC.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, methods, modules and instruments for automated nuclei...
Patent number
11,845,932
Issue date
Dec 19, 2023
Inscripta, Inc.
Burak Dura
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mammalian cell line for protein production and library generation
Patent number
11,802,281
Issue date
Oct 31, 2023
ETH ZURICH
Sai Reddy
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
CRISPR enabled multiplexed genome engineering
Patent number
11,795,479
Issue date
Oct 24, 2023
The Regents of the University of Colorado
Andrew Garst
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
HIV vaccines and methods of making and using
Patent number
11,795,210
Issue date
Oct 24, 2023
Gilead Sciences, Inc.
Xinan Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR/Cas dropout screening platform to reveal genetic vulnerabili...
Patent number
11,781,131
Issue date
Oct 10, 2023
REGENERON PHARMACEUTICALS, INC.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA extraction method using microwave for next generation sequencin...
Patent number
11,781,132
Issue date
Oct 10, 2023
Macrogen, Inc.
Joshua Sungwoo Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multiplex genome engineering in eukaryotes
Patent number
11,725,204
Issue date
Aug 15, 2023
Yale University
Edward Barbieri
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Phosphopeptide-encoding oligonucleotide libraries and methods for d...
Patent number
11,718,849
Issue date
Aug 8, 2023
Agilent Technologies, Inc.
Jesse Rinehart
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR enabled multiplexed genome engineering
Patent number
11,702,677
Issue date
Jul 18, 2023
The Regents of the University of Colorado
Andrew Garst
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Compact scaffold of Cas9 in the type II CRISPR system
Patent number
11,685,935
Issue date
Jun 27, 2023
Cellectis
Philippe Duchateau
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Functional genomics using CRISPR-Cas systems for saturating mutagen...
Patent number
11,685,917
Issue date
Jun 27, 2023
The Broad Institute, Inc.
Daniel E. Bauer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genome editing
Patent number
11,667,933
Issue date
Jun 6, 2023
Julius Fredens
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted integration into the PPP1R12C locus
Patent number
11,649,468
Issue date
May 16, 2023
Sangamo Therapeutics, Inc.
Russell DeKeiver
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR enabled multiplexed genome engineering
Patent number
11,639,511
Issue date
May 2, 2023
The Regents of the University of Colorado, a Body Corporate
Andrew Garst
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR editing to embed nucleic acid landing pads into genomes of l...
Patent number
11,597,923
Issue date
Mar 7, 2023
Inscripta, Inc.
Daniel Held
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Automated cell processing methods, modules, instruments, and systems
Patent number
11,597,921
Issue date
Mar 7, 2023
Inscripta, Inc.
Jorge Bernate
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Optimized CRISPR-Cas double nickase systems, methods and compositio...
Patent number
11,597,949
Issue date
Mar 7, 2023
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, methods, modules and instruments for automated nuclei...
Patent number
11,591,592
Issue date
Feb 28, 2023
Inscripta, Inc.
Phillip Belgrader
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Compositions and methods of use of CRISPR-Cas systems in nucleotide...
Patent number
11,591,581
Issue date
Feb 28, 2023
The Broad Institute, Inc.
Feng Zhang
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Methods and compositions for generating a deletion library and for...
Patent number
11,584,931
Issue date
Feb 21, 2023
The J. David Gladstone Institutes
Leor S. Weinberger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for generating barcoded combinatorial libraries
Patent number
11,584,928
Issue date
Feb 21, 2023
The Regents of the University of Colorado, a Body Corporate
Ryan T. Gill
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method and system for CRISPR-based library preparation and sequencing
Patent number
11,572,555
Issue date
Feb 7, 2023
PSOMAGEN, INC.
Zachary Apte
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for studying cell evolution
Patent number
11,547,614
Issue date
Jan 10, 2023
The Broad Institute, Inc.
Pratiti Bandopadhayay
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
METHODS AND COMPOSITIONS FOR MUTAGENESIS SCREENING IN MAMMALIAN CELLS
Publication number
20240141330
Publication date
May 2, 2024
The Board of Regents of the University of Texas System
Ralf KITTLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS, METHODS, MODULES AND INSTRUMENTS FOR AUTOMATED NUCLEI...
Publication number
20240141331
Publication date
May 2, 2024
Inscripta, Inc.
Burak Dura
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY
Publication number
20240132970
Publication date
Apr 25, 2024
Flagship Pioneering Innovations VI, LLC.
Anthony P. Shuber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IDENTIFICATION OF GENOMIC TARGETS
Publication number
20240124872
Publication date
Apr 18, 2024
UNIVERSITY OF LEEDS
Viktor Lukacs
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF CRISPR SYSTEMS AND CO...
Publication number
20240117382
Publication date
Apr 11, 2024
THE BROAD INSTITUTE, INC.
David Benjamin Turitz Cox
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SELECTION BY ESSENTIAL-GENE KNOCK-IN
Publication number
20240117383
Publication date
Apr 11, 2024
EDITAS MEDICINE, INC.
John Anthony Zuris
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HIV VACCINES AND METHODS OF MAKING AND USING
Publication number
20240117017
Publication date
Apr 11, 2024
GILEAD SCIENCES, INC.
Xinan Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITION AND METHOD FOR HIGH-MULTIPLEXED GENOME ENGINEERING USIN...
Publication number
20240110175
Publication date
Apr 4, 2024
The Board of Trustees of the Leland Stanford Junior University
Jens Peter MAGNUSSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS FOR SATURATING MUTAGEN...
Publication number
20240102004
Publication date
Mar 28, 2024
THE BROAD INSTITUTE, INC.
Daniel E. Bauer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR ISOLATING AND/OR OBTAINING CAPTURED POLYNUCLEOTIDE FRAG...
Publication number
20240093181
Publication date
Mar 21, 2024
Cosimo JANN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions and Methods of Treating Ocular Diseases
Publication number
20240091378
Publication date
Mar 21, 2024
The Regents of the University of California
David V. Schaffer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CRISPR ENABLED MULTIPLEXED GENOME ENGINEERING
Publication number
20240093241
Publication date
Mar 21, 2024
The Regents of the University of Colorado, a Body Corporate
Andrew GARST
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
CRISPR/CAS SCREENING PLATFORM TO IDENTIFY GENETIC MODIFIERS OF TAU...
Publication number
20240084293
Publication date
Mar 14, 2024
Regeneron Pharmaceuticals, Inc.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MAMMALIAN CELLS AND METHODS FOR ENGINEERING THE SAME
Publication number
20240076655
Publication date
Mar 7, 2024
64-X, Inc.
Alexis Rovner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED ENVELOPED VECTORS AND METHODS OF USE THEREOF
Publication number
20240067958
Publication date
Feb 29, 2024
GigaMune, Inc.
David Scott JOHNSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AUTOCATALYTIC BASE EDITING FOR RNA-RESPONSIVE TRANSLATIONAL CONTROL
Publication number
20240067957
Publication date
Feb 29, 2024
Massachusetts Institute of Technology
James J. Collins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEMS AND METHODS FOR GENOME-WIDE ANNOTATION OF GENE REGULATORY E...
Publication number
20240058425
Publication date
Feb 22, 2024
DUKE UNIVERSITY
Charles A. Gersbach
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MAMMALIAN CELLS AND METHODS FOR ENGINEERING THE SAME
Publication number
20240052341
Publication date
Feb 15, 2024
64-X, Inc.
Alexis Rovner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FAST-TRACK HUMANISATION OF SPECIFIC BINDING MOLECULES
Publication number
20240035020
Publication date
Feb 1, 2024
ELASMOGEN LTD
Caroline Jane BARELLE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR GENERATING A DELETION LIBRARY AND FOR...
Publication number
20240035021
Publication date
Feb 1, 2024
THE J. DAVID GLADSTONE INSTITUTES
Leor S. Weinberger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION
Publication number
20240018513
Publication date
Jan 18, 2024
Fred Hutchinson Cancer Center
Robert K. Bradley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Method for multi-dimensional analysis of cell epigenomics
Publication number
20240018512
Publication date
Jan 18, 2024
BGI Shenzhen
Chunqing Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING A GENOME
Publication number
20240002886
Publication date
Jan 4, 2024
Flagship Pioneering Innovations VI, LLC.
Robert Charles Altshuler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
VIRAL VECTOR-PRODUCING CELLS HAVING IMPROVED ABILITY TO PRODUCE VEC...
Publication number
20240002883
Publication date
Jan 4, 2024
AGC Inc.
Chinatsu MORIYAMA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR/CAS DROPOUT SCREENING PLATFORM TO REVEAL GENETIC VULNERABILI...
Publication number
20230416728
Publication date
Dec 28, 2023
Regeneron Pharmaceuticals, Inc.
Marine Prissette
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Barcoded Cells Engineered With Heterozygous Genetic Diversity
Publication number
20230399638
Publication date
Dec 14, 2023
University of South Alabama Foundation for Research and Commercialization
Robert W. Sobol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BIG-IN: A VERSATILE PLATFORM FOR LOCUS-SCALE GENOME REWRITING AND V...
Publication number
20230392170
Publication date
Dec 7, 2023
NEW YORK UNIVERSITY
Ran BROSH
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR/Cas9 MULTIPLEX KNOCKOUT OF HOST CELL PROTEINS
Publication number
20230374497
Publication date
Nov 23, 2023
Genentech, Inc.
Amy SHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MAMMALIAN CELL LINE FOR PROTEIN PRODUCTION AND LIBRARY GENERATION
Publication number
20230374491
Publication date
Nov 23, 2023
ETH ZURICH
Sai REDDY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OPTIMIZED CRISPR-CAS DOUBLE NICKASE SYSTEMS, METHODS AND COMPOSITIO...
Publication number
20230374550
Publication date
Nov 23, 2023
THE BROAD INSTITUTE, INC.
Feng ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...