Receptor protein-tyrosine kinase (2.7.10.1)

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CPC
C12Y207/10001

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CCHEMISTRY METALLURGY C12Biochemistry C12YENZYMES C12Y207/00Transferases transferring phosphorus-containing groups (2.7)

Current Industry

C12Y207/10001Receptor protein-tyrosine kinase (2.7.10.1)

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Patents Grantslast 30 patents

Information Patent Grant
Method of using NAP-2 and TGF-α to improve cardiac function
- Patent number 12,357,676
- Issue date Jul 15, 2025
- Mayo Foundation for Medical Education and Research
- Atta Behfar
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Cancer stem cell targeted cancer vaccines
- Patent number 12,357,678
- Issue date Jul 15, 2025
- Stemline Therapeutics, Inc.
- Ivan Bergstein
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Neoantigen peptide mimics
- Patent number 12,275,766
- Issue date Apr 15, 2025
- Janssen Biotech, Inc.
- Vinod Krishna
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of treating cholangiocarcinoma
- Patent number 12,274,699
- Issue date Apr 15, 2025
- Foundation Medicine, Inc.
- Siraj Mahamed Ali
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Production of engineered T-cells by sleeping beauty transposon coup...
- Patent number 12,258,397
- Issue date Mar 25, 2025
- Seattle Children's Hospital
- Michael C. Jensen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Drug regulated transgene expression
- Patent number 12,202,897
- Issue date Jan 21, 2025
- Seattle Children's Hospital
- Michael C. Jensen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Expression of novel cell tags
- Patent number 12,180,517
- Issue date Dec 31, 2024
- PRECIGEN, INC.
- Rutul Shah
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
C-KIT antibodies and method for treating cancer with such
- Patent number 12,173,067
- Issue date Dec 24, 2024
- Granular Therapeutics Limited
- William James Jonathan Finlay
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fully stabilized asymmetric siRNA
- Patent number 12,173,286
- Issue date Dec 24, 2024
- UNIVERSITY OF MASSACHUSETTS
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Crenolanib for treating FLT3 mutated proliferative disorders
- Patent number 12,171,757
- Issue date Dec 24, 2024
- AROG PHARMACEUTICALS, INC.
- Vinay K. Jain
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Vaccines against an oncogenic isoform of HER2 (ErbB2) and methods o...
- Patent number 12,083,172
- Issue date Sep 10, 2024
- Duke University
- Herbert K. Lyerly
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Expression of novel cell tags
- Patent number 12,060,585
- Issue date Aug 13, 2024
- PRECIGEN, INC.
- Rutul Shah
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-TrkB agonist antibodies binding to D1 domain of TrkB
- Patent number 12,037,400
- Issue date Jul 16, 2024
- Tsinghua University
- Bai Lu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetically engineered drug resistant T cells and methods of using...
- Patent number 12,005,078
- Issue date Jun 11, 2024
- The UAB Research Foundation
- Lawrence S. Lamb
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Exosome-based anticancer agent
- Patent number 11,952,412
- Issue date Apr 9, 2024
- SHIFTBIO
- Eun-ee Koh
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method of treating aging-associated cognitive impairment by reducin...
- Patent number 11,912,998
- Issue date Feb 27, 2024
- The Board of Trustees of the Leland Stanford Junior University
- Anton Wyss-Coray
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-kit antibodies and uses thereof
- Patent number 11,891,452
- Issue date Feb 6, 2024
- Celldex Therapeutics, Inc.
- Yaron Hadari
- G01 - MEASURING TESTING
Information Patent Grant
Ligand binding molecules and uses thereof
- Patent number 11,866,739
- Issue date Jan 9, 2024
- Vegenics Pty Limited
- Michael Gerometta
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for...
- Patent number 11,814,654
- Issue date Nov 14, 2023
- Institut National de la Sante et de la Recherche Medicale
- Elvire Gouze
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Activation of APC in immunotherapy
- Patent number 11,788,072
- Issue date Oct 17, 2023
- Innovative Cellular Therapeutics Holdings, Ltd.
- Chengfei Pu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of treating cholangiocarcinoma
- Patent number 11,771,698
- Issue date Oct 3, 2023
- Foundation Medicine, Inc.
- Siraj Mahamed Ali
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for...
- Patent number 11,702,642
- Issue date Jul 18, 2023
- INSERM (Institut National de la Sante et de la Recherche Medicale)
- Elvire Gouze
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cancer stem cell targeted cancer vaccines
- Patent number 11,672,847
- Issue date Jun 13, 2023
- Stemline Therapeutics, Inc.
- Ivan Bergstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Receptor tyrosine kinase biomarkers
- Patent number 11,567,073
- Issue date Jan 31, 2023
- United Kingdom Research and Innovation
- Marisa Martin-Fernandez
- G01 - MEASURING TESTING
Information Patent Grant
Compositions for detecting mutant anaplastic lymphoma kinase in lun...
- Patent number 11,505,833
- Issue date Nov 22, 2022
- Cell Signaling Technology, Inc.
- Klarisa Rikova
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Fusion proteins and methods thereof
- Patent number 11,505,788
- Issue date Nov 22, 2022
- The Trustees of Columbia University In the City of New York
- Antonio Iavarone
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Crenolanib for treating FLT3 mutated proliferative disorders
- Patent number 11,458,131
- Issue date Oct 4, 2022
- AROG PHARMACEUTICALS, INC.
- Vinay K. Jain
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for evaluating quality of human mesenchymal stem cell, and m...
- Patent number 11,441,123
- Issue date Sep 13, 2022
- PUREC CO., LTD.
- Yumi Iyoku
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetically modified rat comprising a humanized TRKB locus
- Patent number 11,419,318
- Issue date Aug 23, 2022
- Regeneran Pharmaceuticals, Inc.
- Alexander O. Mujica
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Using nucleic acids encoding NAP-2 polypeptides to improve cardiac...
- Patent number 11,413,330
- Issue date Aug 16, 2022
- Mayo Foundation for Medical Education and Research
- Atta Behfar
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
ANTI-EGFR ANTIBODIES, ANTI-CMET ANTIBODIES, ANTI-VEGF ANTIBODIES, M...
- Publication number 20250230248
- Publication date Jul 17, 2025
- Tavotek Biotherapeutics (Hong Kong) Limited
- Pu PU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIGEN-SPECIFIC THERAPY FOR AUTOIMMUNE DISEASES
- Publication number 20250195633
- Publication date Jun 19, 2025
- BODHI BIO LLC
- Animesh Sinha
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF TREATING CHOLANGIOCARCINOMA
- Publication number 20250195514
- Publication date Jun 19, 2025
- Foundation Medicine, Inc.
- Siraj Mahamed Ali
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FULLY STABILIZED ASYMMETRIC SIRNA
- Publication number 20250188458
- Publication date Jun 12, 2025
- University of Massachusetts
- Anastasia Khvorova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
EPITOPE ENGINEERING OF CELL-SURFACE RECEPTORS
- Publication number 20250170182
- Publication date May 29, 2025
- Dana-Farber Cancer Institute, Inc.
- Pietro Genovese
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY ENGINEERED DRUG RESISTANT T CELLS AND METHODS OF USING...
- Publication number 20250073228
- Publication date Mar 6, 2025
- The UAB Research Foundation
- Lawrence S. Lamb
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
C-KIT ANTIBODIES
- Publication number 20250066475
- Publication date Feb 27, 2025
- GRANULAR THERAPEUTICS LIMITED
- William James Jonathan Finlay
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANAPLASTIC LYMPHOMA KINASE (ALK) CANCER VACCINES AND METHODS OF USE...
- Publication number 20250057930
- Publication date Feb 20, 2025
- The Children's Medical Center Corporation
- Roberto Chiarle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Crenolanib for Treating FLT3 Mutated Proliferative Disorders
- Publication number 20250032475
- Publication date Jan 30, 2025
- Arog Pharmaceuticals, Inc.
- Vinay K. Jain
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Crystal Structures of ALK and LTK Receptor Tyrosine Kinases and The...
- Publication number 20250027060
- Publication date Jan 23, 2025
- VIB VZW
- Savvas Savvides
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR TARGETING ALTERNATIVE METABOLISM ALONG...
- Publication number 20250009740
- Publication date Jan 9, 2025
- Ohio State Innovation Foundation
- Rosa LAPALOMBELLA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-H...
- Publication number 20240415103
- Publication date Dec 19, 2024
- Regeneron Pharmaceuticals, Inc.
- Davor Frleta
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TREATMENT OF MST1R RELATED DISEASES AND DISORDERS
- Publication number 20240392299
- Publication date Nov 28, 2024
- EMPIRICO INC.
- Omri GOTTESMAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Ligand Binding Molecules and Uses Thereof
- Publication number 20240301370
- Publication date Sep 12, 2024
- VEGENICS PTY LIMITED
- MICHAEL GEROMETTA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MERTK PEPTIDES AND USES THEREOF
- Publication number 20240279347
- Publication date Aug 22, 2024
- Inspirna, Inc.
- Masoud Tavazoie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING
- Publication number 20240228552
- Publication date Jul 11, 2024
- University of Massachusetts
- Min Chen
- B82 - NANO-TECHNOLOGY
Information Patent Application
FUSION PROTEIN TARGETING PD-L1 AND NEUTRALIZING GAS6 AND USES THEREOF
- Publication number 20240218337
- Publication date Jul 4, 2024
- Development Center for Biotechnology
- CHU-BIN LIAO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL EXOSOME-BASED ANTICANCER AGENT
- Publication number 20240209063
- Publication date Jun 27, 2024
- SHIFTBIO INC.
- Eun-ee KOH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOMARKERS OF AGING FOR DETECTION AND TREATMENT OF DISORDERS
- Publication number 20240191238
- Publication date Jun 13, 2024
- The Board of Trustees of the Leland Stanford Junior University
- Anton Wyss-Coray
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-KIT ANTIBODIES AND USES THEREOF
- Publication number 20240150493
- Publication date May 9, 2024
- CELLDEX THERAPEUTICS, INC.
- Yaron Hadari
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL CELL LINES, METHODS OF PRODUCING NATURAL KILLER CELLS AND USE...
- Publication number 20240141295
- Publication date May 2, 2024
- CITY OF HOPE
- Jianhua Yu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING
- Publication number 20240132551
- Publication date Apr 25, 2024
- University of Massachusetts
- Min Chen
- B82 - NANO-TECHNOLOGY
Information Patent Application
Cancer Stem Cell Targeted Cancer Vaccines
- Publication number 20240115677
- Publication date Apr 11, 2024
- STEMLINE THERAPEUTICS, INC.
- Ivan Bergstein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Ocular Compositions and Methods Thereof
- Publication number 20240009120
- Publication date Jan 11, 2024
- UNIVERSITY OF MISSISSIPPI MEDICAL CENTER
- Gene L. Bidwell
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR ALLOGENEIC TRANSPLANTATION
- Publication number 20230390412
- Publication date Dec 7, 2023
- Magenta Therapeutics, Inc.
- Geoffrey O. Gillard
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF TREATING CHOLANGIOCARCINOMA
- Publication number 20230372338
- Publication date Nov 23, 2023
- FOUNDATION MEDICINE, INC.
- Siraj Mahamed Ali
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR DENDRITIC CELLS (CAR-DCS) AND METHODS OF...
- Publication number 20230355765
- Publication date Nov 9, 2023
- Washington University
- CARL DESELM
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUSION PROTEINS AND METHODS THEREOF
- Publication number 20230303985
- Publication date Sep 28, 2023
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Antonio IAVARONE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECEPTOR TYROSINE KINASE BIOMARKERS
- Publication number 20230204578
- Publication date Jun 29, 2023
- United Kingdom Research and Innovation
- Marisa Martin-Fernandez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC RECEPTORS TO FLT3 AND METHODS OF USE THEREOF
- Publication number 20230124464
- Publication date Apr 20, 2023
- Amgen, Inc.
- Alice BAKKER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Receptor protein-tyrosine kinase (2.7.10.1)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Method of using NAP-2 and TGF-α to improve cardiac function

Cancer stem cell targeted cancer vaccines

Neoantigen peptide mimics

Methods of treating cholangiocarcinoma

Production of engineered T-cells by sleeping beauty transposon coup...

Drug regulated transgene expression

Expression of novel cell tags

C-KIT antibodies and method for treating cancer with such

Fully stabilized asymmetric siRNA

Crenolanib for treating FLT3 mutated proliferative disorders

Vaccines against an oncogenic isoform of HER2 (ErbB2) and methods o...

Expression of novel cell tags

Anti-TrkB agonist antibodies binding to D1 domain of TrkB

Genetically engineered drug resistant T cells and methods of using...

Exosome-based anticancer agent

Method of treating aging-associated cognitive impairment by reducin...

Anti-kit antibodies and uses thereof

Ligand binding molecules and uses thereof

Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for...

Activation of APC in immunotherapy

Methods of treating cholangiocarcinoma

Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for...

Cancer stem cell targeted cancer vaccines

Receptor tyrosine kinase biomarkers

Compositions for detecting mutant anaplastic lymphoma kinase in lun...

Fusion proteins and methods thereof

Crenolanib for treating FLT3 mutated proliferative disorders

Method for evaluating quality of human mesenchymal stem cell, and m...

Genetically modified rat comprising a humanized TRKB locus

Using nucleic acids encoding NAP-2 polypeptides to improve cardiac...

Patents Applicationslast 30 patents

ANTI-EGFR ANTIBODIES, ANTI-CMET ANTIBODIES, ANTI-VEGF ANTIBODIES, M...

ANTIGEN-SPECIFIC THERAPY FOR AUTOIMMUNE DISEASES

METHODS OF TREATING CHOLANGIOCARCINOMA

FULLY STABILIZED ASYMMETRIC SIRNA

EPITOPE ENGINEERING OF CELL-SURFACE RECEPTORS

GENETICALLY ENGINEERED DRUG RESISTANT T CELLS AND METHODS OF USING...

C-KIT ANTIBODIES

ANAPLASTIC LYMPHOMA KINASE (ALK) CANCER VACCINES AND METHODS OF USE...

Crenolanib for Treating FLT3 Mutated Proliferative Disorders

Crystal Structures of ALK and LTK Receptor Tyrosine Kinases and The...

METHODS AND COMPOSITIONS FOR TARGETING ALTERNATIVE METABOLISM ALONG...

VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-H...

TREATMENT OF MST1R RELATED DISEASES AND DISORDERS

Ligand Binding Molecules and Uses Thereof

MERTK PEPTIDES AND USES THEREOF

NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING

FUSION PROTEIN TARGETING PD-L1 AND NEUTRALIZING GAS6 AND USES THEREOF

NOVEL EXOSOME-BASED ANTICANCER AGENT

BIOMARKERS OF AGING FOR DETECTION AND TREATMENT OF DISORDERS

ANTI-KIT ANTIBODIES AND USES THEREOF

NOVEL CELL LINES, METHODS OF PRODUCING NATURAL KILLER CELLS AND USE...

NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING

Cancer Stem Cell Targeted Cancer Vaccines

Ocular Compositions and Methods Thereof

COMPOSITIONS AND METHODS FOR ALLOGENEIC TRANSPLANTATION

METHODS OF TREATING CHOLANGIOCARCINOMA

CHIMERIC ANTIGEN RECEPTOR DENDRITIC CELLS (CAR-DCS) AND METHODS OF...

FUSION PROTEINS AND METHODS THEREOF

RECEPTOR TYROSINE KINASE BIOMARKERS

CHIMERIC RECEPTORS TO FLT3 AND METHODS OF USE THEREOF