Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts

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AHUMAN NECESSITIES A61Medical science A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES A61K49/00Preparations for testing in vivo

Current Industry

A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts

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Patents Grantslast 30 patents

Information Patent Grant
Viral preparations and methods for treating and modulating mitochon...
- Patent number 12,297,460
- Issue date May 13, 2025
- Julian Daich
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Prophylactic and/or therapeutic agent of infectious diseases or inf...
- Patent number 12,281,158
- Issue date Apr 22, 2025
- A-CLIP INSTITUTE, CO., LTD.
- Kazuo Suzuki
- G01 - MEASURING TESTING
Information Patent Grant
Genetically modified mouse with a humanized PNPLA3 gene and methods...
- Patent number 12,250,931
- Issue date Mar 18, 2025
- REGENERON PHARMACEUTICALS, INC.
- Xiping Cheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibodies to human B7x for treatment of metastatic cancer
- Patent number 12,221,489
- Issue date Feb 11, 2025
- Albert Einstein College of Medicine
- Xingxing Zang
- G01 - MEASURING TESTING
Information Patent Grant
GRP78-binding antibodies and uses thereof in detecting or neutraliz...
- Patent number 12,180,269
- Issue date Dec 31, 2024
- Rutgers, The State University of New Jersey
- Renata Pasqualini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Phage-displayed accessible recombinant targeted antibodies and meth...
- Patent number 12,168,685
- Issue date Dec 17, 2024
- Rutgers, The State University of New Jersey
- Renata Pasqualini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of treating an inflammatory disorder by administering an an...
- Patent number 12,162,937
- Issue date Dec 10, 2024
- Board of Regents of the University of Texas System
- Jean X. Jiang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treatment with anti-PACAP antibodies
- Patent number 12,162,936
- Issue date Dec 10, 2024
- H. Lundbeck A/S
- Maria-Cristina Loomis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-human animals having a humanized signal-regulatory protein gene
- Patent number 12,161,097
- Issue date Dec 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Compositions and methods for modulating neuronal excitability and m...
- Patent number 12,163,130
- Issue date Dec 10, 2024
- Icahn School of Medicine at Mount Sinai
- Anne Schaefer
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Humanized M-CSF mice
- Patent number 12,127,536
- Issue date Oct 29, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Isoform-selective TGFB1 inhibitors and use thereof
- Patent number 12,122,823
- Issue date Oct 22, 2024
- SCHOLAR ROCK, INC.
- Abhishek Datta
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Use of alveolar or airway organoids for the treatment of lung disea...
- Patent number 12,109,242
- Issue date Oct 8, 2024
- THE CHILDREN'S MEDICAL CENTER CORPORATION
- Carla F. Kim
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
GRP78-binding antibodies and uses thereof in detecting or neutraliz...
- Patent number 12,103,966
- Issue date Oct 1, 2024
- Rutgers, The State University of New Jersey
- Renata Pasqualini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Non-human animals having a humanized lymphocyte-activation gene 3
- Patent number 12,096,754
- Issue date Sep 24, 2024
- REGENERON PHARMACEUTICALS, INC.
- Alexander O. Mujica
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Genetically modified mouse that expresses humanized PD1 and PD-L1 p...
- Patent number 12,089,575
- Issue date Sep 17, 2024
- REGENERON PHARMACEUTICALS, INC.
- Elena Burova
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Rodent animals expressing human CR1
- Patent number 12,082,566
- Issue date Sep 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Anti-PACAP antibodies and uses thereof
- Patent number 12,077,581
- Issue date Sep 3, 2024
- H. Lundbeck A/S
- Maria-Cristina Loomis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of reducing toxicity induced by Amyloid beta (A-beta) oligo...
- Patent number 12,071,472
- Issue date Aug 27, 2024
- The University of British Columbia
- Neil R. Cashman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
GRP78-binding antibodies and uses thereof and selection of phage-di...
- Patent number 12,060,415
- Issue date Aug 13, 2024
- Rutgers, The State University of New Jersey
- Renata Pasqualini
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Treatment for autistic spectrum disorder (ASD) and relevant symptoms
- Patent number 12,059,433
- Issue date Aug 13, 2024
- Academia Sinica
- Yi-Ping Hsueh
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Transgenic mouse model of Neurofibromatosis type 1
- Patent number 12,052,979
- Issue date Aug 6, 2024
- 1. PARIS SCIENCES ET LETTRES—QUARTIER LATIN
- Piotr Topilko
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Methods of using humanized FCγR mice to assay Fc regions
- Patent number 12,036,288
- Issue date Jul 16, 2024
- REGENERON PHARMACEUTICALS, INC.
- Lynn MacDonald
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Genetically modified non-human animal with human or chimeric CD3e
- Patent number 12,016,315
- Issue date Jun 25, 2024
- Biocytogen Pharmaceuticals (Beijing) Co., Ltd
- Yuelei Shen
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Animal model for SARS-CoV-2-spike induced coagulopathy
- Patent number 12,016,934
- Issue date Jun 25, 2024
- The J. David Gladstone Institutes, A Testamentary Trust Established Under The...
- Katerina Akassoglou
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Transthyretin antibodies and uses thereof
- Patent number 12,006,357
- Issue date Jun 11, 2024
- Mor Research Applications Ltd.
- Michael Fassler
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for treating and diagnosing blinding eye diseases
- Patent number 11,992,534
- Issue date May 28, 2024
- Translatum Medicus Inc.
- Shelley Romayne Boyd
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Screening method for identifying anti-PACAP antibodies or antibody...
- Patent number 11,993,648
- Issue date May 28, 2024
- H. Lundbeck A/S
- Adisa Kuburas
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method for testing ecotoxicity of disinfection by-products
- Patent number 11,977,068
- Issue date May 7, 2024
- Tongji University
- Wenhai Chu
- G01 - MEASURING TESTING
Information Patent Grant
Transgenic C57BL6-BTBR mouse with a humanized MHC II gene that expr...
- Patent number 11,974,552
- Issue date May 7, 2024
- The University of Toledo
- Shahnawaz Imam
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING

Patents Applicationslast 30 patents

Information Patent Application
ASSESSMENT OF ADVERSE EVENTS INDUCED BY ADMINISTRATION OF ANTITUMOR...
- Publication number 20250152749
- Publication date May 15, 2025
- Tohoku University
- Tetsuya KODAMA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD FOR DETERMINING ACUTE TOXICITY AND A SYSTEM USING SAID METHOD
- Publication number 20250093331
- Publication date Mar 20, 2025
- City University of Hong Kong
- Wenxiong WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHOD AND DEVICE FOR DRUG SCREENING
- Publication number 20250093330
- Publication date Mar 20, 2025
- Shanghai Lide Biotech Co., Ltd.
- Danyi Wen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Humanized M-CSF Mice
- Publication number 20250072406
- Publication date Mar 6, 2025
- Regeneron Pharmaceuticals, Inc.
- Andrew J. Murphy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY AND M...
- Publication number 20250075215
- Publication date Mar 6, 2025
- Icahn School of Medicine at Mount Sinai
- Anne SCHAEFER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Compositions and Methods for Targeting Connexin Hemichannels
- Publication number 20250059272
- Publication date Feb 20, 2025
- Board of Regents, The University of Texas System
- Jean X. Jiang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEA...
- Publication number 20250057888
- Publication date Feb 20, 2025
- Carla F. KIM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODIES TO AMYLOID BETA
- Publication number 20250051428
- Publication date Feb 13, 2025
- The University of British Columbia
- Neil R. Cashman
- G01 - MEASURING TESTING
Information Patent Application
NUCLEIC ACID COMPOSITIONS AND USES THEREOF
- Publication number 20250049951
- Publication date Feb 13, 2025
- SURGE Therapeutics, Inc.
- Michael Solomon Goldberg
- G01 - MEASURING TESTING
Information Patent Application
SCREENING METHOD OF PROBIOTIC AND ACTIVE SUBSTANCE FOR PROMOTING RE...
- Publication number 20250031679
- Publication date Jan 30, 2025
- XUZHOU MEDICAL UNIVERSITY
- Zuobin ZHU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MUTANT TDP-43 PROTEIN
- Publication number 20250002547
- Publication date Jan 2, 2025
- TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
- Takashi NONAKA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TRANSTHYRETIN ANTIBODIES AND USES THEREOF
- Publication number 20250002568
- Publication date Jan 2, 2025
- MOR RESEARCH APPLICATIONS LTD.
- Michael FASSLER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
LOW AFFINITY FcyR DEFICIENT MICE
- Publication number 20240424145
- Publication date Dec 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Lynn MacDonald
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DRUG SCREENING METHOD AND MODEL FOR MONITORING PLATINUM-RESISTANT O...
- Publication number 20240424146
- Publication date Dec 26, 2024
- THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
- Bethany N. HANNAFON
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-H...
- Publication number 20240415103
- Publication date Dec 19, 2024
- Regeneron Pharmaceuticals, Inc.
- Davor Frleta
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Animal Model With Rapid Onset Of Alzheimer's Amyloid Beta Plaque Pa...
- Publication number 20240408246
- Publication date Dec 12, 2024
- Regeneron Pharmaceuticals, Inc.
- Brian Huang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED LYMPHOCYTE-ACTIVATION GENE 3
- Publication number 20240397919
- Publication date Dec 5, 2024
- Regeneron Pharmaceuticals, Inc.
- Alexander O. Mujica
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHETIC SCAFFOLDS FOR METASTASIS DETECTION
- Publication number 20240398995
- Publication date Dec 5, 2024
- Northwestern University
- Lonnie D. Shea
- C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information Patent Application
GENETICALLY MODIFIED MOUSE THAT EXPRESSES HUMANIZED PD1 AND PD-L1 P...
- Publication number 20240389563
- Publication date Nov 28, 2024
- Regeneron Pharmaceuticals, Inc.
- Elena Burova
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR
- Publication number 20240374761
- Publication date Nov 14, 2024
- RADIUS PHARMACEUTICALS, INC.
- Beate Klara Maria MANNSTADT
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
GRP78-BINDING ANTIBODIES AND USE THEREOF IN DETECTING OR NEUTRALIZI...
- Publication number 20240368258
- Publication date Nov 7, 2024
- Rutgers, The State University of New Jersey
- Renata PASQUALINI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHAPERONES AS AN AUTOPHAGY RECEPTORS FOR CLEARANCES OF PROTEIN AGGR...
- Publication number 20240350586
- Publication date Oct 24, 2024
- TSINGHUA UNIVERSITY
- Liang GE
- G01 - MEASURING TESTING
Information Patent Application
RODENT ANMALS EXPRESSING HUMAN CR1
- Publication number 20240315221
- Publication date Sep 26, 2024
- Regeneron Pharmaceuticals, Inc.
- Andrew J. MURPHY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND COMPOSITIONS FOR CANCER TREATMENT BY TARGETING AXL SIGN...
- Publication number 20240307390
- Publication date Sep 19, 2024
- SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
- Charles SPRUCK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS AND COMPOSITIONS FOR TREATING CHRONIC LIVER DISEASE AND HEP...
- Publication number 20240301417
- Publication date Sep 12, 2024
- SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
- Cynthia LEBEAUPIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENE
- Publication number 20240298619
- Publication date Sep 12, 2024
- Regeneron Pharmaceuticals, Inc.
- Elena BUROVA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PEPTIDE FOR TREATING AGE-RELATED MACULAR DEGENERATION
- Publication number 20240294610
- Publication date Sep 5, 2024
- DAIICHI SANKYO COMPANY, LIMITED
- Daisuke Nishimiya
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NME INHIBITORS AND METHODS OF USING NME INHIBITORS
- Publication number 20240277803
- Publication date Aug 22, 2024
- Minerva Biotechnologies Corporation
- Cynthia Bamdad
- G01 - MEASURING TESTING
Information Patent Application
ULTRABRIGHT CHEMILUMINESCENT PROBES FOR DETECTION AND IMAGING
- Publication number 20240277873
- Publication date Aug 22, 2024
- Nanyang Technological University
- Kanyi PU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
POLY-ADP RIBOSE (PAR) TRACKER OPTIMIZED SPLIT-PROTEIN REASSEMBLY PA...
- Publication number 20240252689
- Publication date Aug 1, 2024
- The Board of Regents of the University of Texas System
- W. Lee KRAUS
- G01 - MEASURING TESTING

Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Viral preparations and methods for treating and modulating mitochon...

Prophylactic and/or therapeutic agent of infectious diseases or inf...

Genetically modified mouse with a humanized PNPLA3 gene and methods...

Antibodies to human B7x for treatment of metastatic cancer

GRP78-binding antibodies and uses thereof in detecting or neutraliz...

Phage-displayed accessible recombinant targeted antibodies and meth...

Methods of treating an inflammatory disorder by administering an an...

Methods of treatment with anti-PACAP antibodies

Non-human animals having a humanized signal-regulatory protein gene

Compositions and methods for modulating neuronal excitability and m...

Humanized M-CSF mice

Isoform-selective TGFB1 inhibitors and use thereof

Use of alveolar or airway organoids for the treatment of lung disea...

GRP78-binding antibodies and uses thereof in detecting or neutraliz...

Non-human animals having a humanized lymphocyte-activation gene 3

Genetically modified mouse that expresses humanized PD1 and PD-L1 p...

Rodent animals expressing human CR1

Anti-PACAP antibodies and uses thereof

Methods of reducing toxicity induced by Amyloid beta (A-beta) oligo...

GRP78-binding antibodies and uses thereof and selection of phage-di...

Treatment for autistic spectrum disorder (ASD) and relevant symptoms

Transgenic mouse model of Neurofibromatosis type 1

Methods of using humanized FCγR mice to assay Fc regions

Genetically modified non-human animal with human or chimeric CD3e

Animal model for SARS-CoV-2-spike induced coagulopathy

Transthyretin antibodies and uses thereof

Methods for treating and diagnosing blinding eye diseases

Screening method for identifying anti-PACAP antibodies or antibody...

Method for testing ecotoxicity of disinfection by-products

Transgenic C57BL6-BTBR mouse with a humanized MHC II gene that expr...

Patents Applicationslast 30 patents

ASSESSMENT OF ADVERSE EVENTS INDUCED BY ADMINISTRATION OF ANTITUMOR...

METHOD FOR DETERMINING ACUTE TOXICITY AND A SYSTEM USING SAID METHOD

METHOD AND DEVICE FOR DRUG SCREENING

Humanized M-CSF Mice

COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY AND M...

Compositions and Methods for Targeting Connexin Hemichannels

USE OF ALVEOLAR OR AIRWAY ORGANOIDS FOR THE TREATMENT OF LUNG DISEA...

ANTIBODIES TO AMYLOID BETA

NUCLEIC ACID COMPOSITIONS AND USES THEREOF

SCREENING METHOD OF PROBIOTIC AND ACTIVE SUBSTANCE FOR PROMOTING RE...

MUTANT TDP-43 PROTEIN

TRANSTHYRETIN ANTIBODIES AND USES THEREOF

LOW AFFINITY FcyR DEFICIENT MICE

DRUG SCREENING METHOD AND MODEL FOR MONITORING PLATINUM-RESISTANT O...

VECTORS, GENETICALLY MODIFIED CELLS, AND GENETICALLY MODIFIED NON-H...

Animal Model With Rapid Onset Of Alzheimer's Amyloid Beta Plaque Pa...

NON-HUMAN ANIMALS HAVING A HUMANIZED LYMPHOCYTE-ACTIVATION GENE 3

SYNTHETIC SCAFFOLDS FOR METASTASIS DETECTION

GENETICALLY MODIFIED MOUSE THAT EXPRESSES HUMANIZED PD1 AND PD-L1 P...

ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR

GRP78-BINDING ANTIBODIES AND USE THEREOF IN DETECTING OR NEUTRALIZI...

CHAPERONES AS AN AUTOPHAGY RECEPTORS FOR CLEARANCES OF PROTEIN AGGR...

RODENT ANMALS EXPRESSING HUMAN CR1

METHODS AND COMPOSITIONS FOR CANCER TREATMENT BY TARGETING AXL SIGN...

METHODS AND COMPOSITIONS FOR TREATING CHRONIC LIVER DISEASE AND HEP...

NON-HUMAN ANIMALS HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENE

PEPTIDE FOR TREATING AGE-RELATED MACULAR DEGENERATION

NME INHIBITORS AND METHODS OF USING NME INHIBITORS

ULTRABRIGHT CHEMILUMINESCENT PROBES FOR DETECTION AND IMAGING

POLY-ADP RIBOSE (PAR) TRACKER OPTIMIZED SPLIT-PROTEIN REASSEMBLY PA...