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Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts
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Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts
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Patents Grants
last 30 patents
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Patent Grant
Device for collecting and culturing fish embryos and method for eva...
Patent number
11,969,481
Issue date
Apr 30, 2024
Zhejiang Academy of Agricultural Sciences
Yanhua Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Drug for retinal degenerative disease associated with photoreceptor...
Patent number
11,931,327
Issue date
Mar 19, 2024
Daiichi Sankyo Company, Limited
Naoki Tsuji
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Method of treating osteoarthritis by administering an anti-connexin...
Patent number
11,912,762
Issue date
Feb 27, 2024
Board of Regents of the University of Texas System
Jean X. Jiang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Animal models of corneal ectatic diseases, methods of producing, an...
Patent number
11,895,992
Issue date
Feb 13, 2024
Arturo Solis Herrera
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Anti-polyethylene glycol (PEG) antibody mouse model for rigorous as...
Patent number
11,890,353
Issue date
Feb 6, 2024
Northwestern University
Evan A. Scott
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Method for culturing 3-dimensional lung cancer organoid and method...
Patent number
11,883,508
Issue date
Jan 30, 2024
ONCOCLEW CO., LTD.
Se Jin Jang
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Cas-ready mouse embryonic stem cells and mice and uses thereof
Patent number
11,866,794
Issue date
Jan 9, 2024
REGENERON PHARMACEUTICALS, INC.
Guochun Gong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions for neuromodulation of mosquito feeding behavior and u...
Patent number
11,839,662
Issue date
Dec 12, 2023
University of Central Florida Research Foundation, Inc.
Bradley Jay Willenberg
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Patent Grant
Single kidney cell-derived organoids
Patent number
11,834,680
Issue date
Dec 5, 2023
Rutgers, The State University of New Jersey
Hatem Sabaawy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Crnn loss of function rodent model
Patent number
11,825,819
Issue date
Nov 28, 2023
REGENERON PHARMACEUTICALS, INC.
Claudia Gonzaga-Jauregui
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Cell and utilization thereof
Patent number
11,814,651
Issue date
Nov 14, 2023
FUJITA ACADEMY
Hideyuki Saya
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Prevention of drug-induced atrio-ventricular block
Patent number
11,806,401
Issue date
Nov 7, 2023
Signpath Pharma, Inc.
Lawrence Helson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Mouse with cholinergic neuron-specific inactivated ANO1 gene
Patent number
11,800,858
Issue date
Oct 31, 2023
Korea University Research and Business Foundation
Jae-Yong Park
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Charged lipoprotein complexes and their uses
Patent number
11,801,282
Issue date
Oct 31, 2023
Abionyx Pharma SA
Jean-Louis Dasseux
C07 - ORGANIC CHEMISTRY
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Patent Grant
Animal model of Angelman Syndrome
Patent number
11,793,177
Issue date
Oct 24, 2023
University of South Florida
Edwin John Weeber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genetically modified non-human animals and methods relating to comp...
Patent number
11,785,923
Issue date
Oct 17, 2023
The Jackson Laboratory
Leonard D. Shultz
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Genetically modified non-human animals and methods of use thereof
Patent number
11,778,995
Issue date
Oct 10, 2023
REGENERON PHARMACEUTICALS, INC.
Richard Flavell
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Genetically modified non-human animals expressing human EPO
Patent number
11,766,032
Issue date
Sep 26, 2023
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Methods of selecting therapeutic molecules
Patent number
11,761,951
Issue date
Sep 19, 2023
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with...
Patent number
11,730,150
Issue date
Aug 22, 2023
REGENERON PHARMACEUTICALS, INC.
Charleen Hunt
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Human liver chimeric mouse with deficient P450 oxidoreductase
Patent number
11,716,974
Issue date
Aug 8, 2023
Baylor College of Medicine
Karl-Dimiter Bissig
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Murine-MHC-deficient HLA-transgenic nod-mouse models for T1D therap...
Patent number
11,712,026
Issue date
Aug 1, 2023
The Jackson Laboratory
David V. Serreze
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Non-human animals comprising a humanized ASGR1 locus
Patent number
11,696,572
Issue date
Jul 11, 2023
REGENERON PHARMACEUTICALS, INC.
Alexander O. Mujica
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Methods for identifying treatments that reduce the actions of subst...
Patent number
11,693,005
Issue date
Jul 4, 2023
Florida Atlantic University Board of trustees
Randy D. Blakely
G01 - MEASURING TESTING
Information
Patent Grant
Tetanus toxoid and CCL3 improve DC vaccines
Patent number
11,684,662
Issue date
Jun 27, 2023
Duke University
John H. Sampson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Non-human animals having a humanized programmed cell death 1 gene
Patent number
11,684,050
Issue date
Jun 27, 2023
Regeneran Pharmaceuticals, Inc.
Elena Burova
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Human innate lymphoid cell precursors: identification, characteriza...
Patent number
11,680,245
Issue date
Jun 20, 2023
Institut Pasteur
James Di Santo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of enhancing immunity
Patent number
11,679,100
Issue date
Jun 20, 2023
The Regents of the University of California
Judith Varner
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method of making a rat model of retinal degeneration and rat model...
Patent number
11,653,636
Issue date
May 23, 2023
University of Ulsan Foundation for Industry Cooperation
Joo Yong Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genetically modified mouse that expresses human albumin
Patent number
11,622,547
Issue date
Apr 11, 2023
Regeneran Pharmaceuticals, Inc.
Qing Fang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
DRUG FOR RETINAL DEGENERATIVE DISEASE ASSOCIATED WITH PHOTORECEPTOR...
Publication number
20240139134
Publication date
May 2, 2024
DAIICHI SANKYO COMPANY, LIMITED
Naoki Tsuji
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Combination therapy for the treatment or prevention of neurological...
Publication number
20240115581
Publication date
Apr 11, 2024
NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
Christiana Bjorkli
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD FOR CULTURING 3-DIMENSIONAL LUNG CANCER ORGANOID AND METHOD...
Publication number
20240108762
Publication date
Apr 4, 2024
ONCOCLEW CO., LTD.
Se Jin JANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS, METHODS, MODELS AND USES FOR SIMIAN VARICELLA VIRUS (...
Publication number
20240091386
Publication date
Mar 21, 2024
The Regents of the University of Colorado, a Body Corporate
Ravi Mahalingam
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CAS-READY MOUSE EMBRYONIC STEM CELLS AND MICE AND USES THEREOF
Publication number
20240093316
Publication date
Mar 21, 2024
Regeneron Pharmaceuticals, Inc.
Guochun Gong
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC FCRN
Publication number
20240081301
Publication date
Mar 14, 2024
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Chengzhang Shang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITION AND USE THEREOF
Publication number
20240082432
Publication date
Mar 14, 2024
Debin CUI
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MODEL OF SPINAL CORD HYPOPERFUSION AND ISCHEMIC STROKE WITH IMMEDIA...
Publication number
20240075169
Publication date
Mar 7, 2024
Ohio State Innovation Foundation
Hesham Kelani
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
Publication number
20240074414
Publication date
Mar 7, 2024
Regeneron Pharmaceuticals, Inc.
Andrew J. Murphy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
APPLICATION OF HELZ2 IN DRUGS FOR PREVENTING AND TREATING TUMORS
Publication number
20230416749
Publication date
Dec 28, 2023
JIANGSU CONCORD BIOTECHNOLOGY CO., LTD
Huabiao CHEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES
Publication number
20230405152
Publication date
Dec 21, 2023
Translatum Medicus Inc.
Shelley Romayne Boyd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Methods for Treating Conditions Associated with MASP-2 Dependent Co...
Publication number
20230391889
Publication date
Dec 7, 2023
University of Leicester
Hans-Wilhelm Schwaeble
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MURINE-MHC-DEFICIENT HLA-TRANSGENIC NOD-MOUSE MODELS FOR T1D THERAP...
Publication number
20230389531
Publication date
Dec 7, 2023
The Jackson Laboratory
David V. Serreze
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
AMYLOID-beta AGGREGATION INHIBITOR, PHARMACEUTICAL COMPOSITION FORA...
Publication number
20230374070
Publication date
Nov 23, 2023
O-FORCE CO., LTD
Toshifumi AKIZAWA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
A HIGH-THROUGHPUT SCREENING METHOD TO DISCOVER OPTIMAL GRNA PAIRS F...
Publication number
20230349888
Publication date
Nov 2, 2023
DUKE UNIVERSITY
Charles A. Gersbach
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
NON-HUMAN ANIMALS COMPRISING A HUMANIZED ASGR1 LOCUS
Publication number
20230345919
Publication date
Nov 2, 2023
Regeneron Pharmaceuticals, Inc.
Alexander O. Mujica
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRANSGENIC ANIMAL PHENOTYPING PLATFORM AND USES THEREOF
Publication number
20230337647
Publication date
Oct 26, 2023
NemaMetrix Inc.
Christopher E. Hopkins
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHOD FOR PRODUCING AVATAR MOUSE AS ATOPIC DERMATITIS ANIMAL MODEL...
Publication number
20230337642
Publication date
Oct 26, 2023
Industry-Academic Cooperation Foundation, Yonsei University
Chang Ook Park
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
HUMAN LIVER CHIMERIC NON-HUMAN ANIMAL WITH DEFICIENT P450 OXIDOREDU...
Publication number
20230337643
Publication date
Oct 26, 2023
Baylor College of Medicine
Karl-Dimiter BISSIG
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
CELLS AND NON-HUMAN ANIMALS ENGINEERED TO EXPRESS ADAR1 AND USES TH...
Publication number
20230329201
Publication date
Oct 19, 2023
WAVE LIFE SCIENCES LTD.
Hailin Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CCR8
Publication number
20230320332
Publication date
Oct 12, 2023
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Yuelei Shen
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MODEL FOR PREDICTION OF TOLERABILITY ISSUES IN CONNECTION WITH INTR...
Publication number
20230322933
Publication date
Oct 12, 2023
BIOINVENT INTERNATIONAL AB
Björn FRENDÉUS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HUMAN INNATE LYMPHOID CELL PRECURSORS: IDENTIFICATION, CHARACTERIZA...
Publication number
20230323304
Publication date
Oct 12, 2023
INSTITUT PASTEUR
James DI SANTO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANIMAL MODEL, METHODS FOR MAKING AND USING THEREOF, AND COMPOSITION...
Publication number
20230309522
Publication date
Oct 5, 2023
City University of Hong Kong
Sungchil YANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BLADDER ORGANOID AND METHOD FOR PRODUCING SAME
Publication number
20230303981
Publication date
Sep 28, 2023
Riken
Minoru TAKASATO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS OF USE THEREOF
Publication number
20230292721
Publication date
Sep 21, 2023
Regeneron Pharmaceuticals, Inc.
Dietmar Herndler-Brandstetter
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
NOVEL COMPOUNDS CAPABLE OF ANTAGONIZING ISLET AMYLOID POLYPEPTIDE (...
Publication number
20230287106
Publication date
Sep 14, 2023
NEURIMMUNE HOLDING AG
Jan GRIMM
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HUMANIZED RODENTS FOR TESTING THERAPEUTIC AGENTS
Publication number
20230277692
Publication date
Sep 7, 2023
Regeneron Pharmaceuticals, Inc.
Vera VORONINA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR PREPARING AN ALZHEIMER'S DISEASE ANIMA...
Publication number
20230256119
Publication date
Aug 17, 2023
BIORCHESTRA Co., Ltd.
Jin-Hyeob RYU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
A HYPERTENSION ANIMAL MODEL AND METHODS OF USE
Publication number
20230233713
Publication date
Jul 27, 2023
Board of Supervisors of Louisiana State University and Agricultural and Mecha...
David J. Lefer
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES