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Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts
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Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts
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Patents Grants
last 30 patents
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Patent Grant
Humanized M-CSF mice
Patent number
12,127,536
Issue date
Oct 29, 2024
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoform-selective TGFB1 inhibitors and use thereof
Patent number
12,122,823
Issue date
Oct 22, 2024
SCHOLAR ROCK, INC.
Abhishek Datta
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Use of alveolar or airway organoids for the treatment of lung disea...
Patent number
12,109,242
Issue date
Oct 8, 2024
THE CHILDREN'S MEDICAL CENTER CORPORATION
Carla F. Kim
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
GRP78-binding antibodies and uses thereof in detecting or neutraliz...
Patent number
12,103,966
Issue date
Oct 1, 2024
Rutgers, The State University of New Jersey
Renata Pasqualini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Non-human animals having a humanized lymphocyte-activation gene 3
Patent number
12,096,754
Issue date
Sep 24, 2024
REGENERON PHARMACEUTICALS, INC.
Alexander O. Mujica
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genetically modified mouse that expresses humanized PD1 and PD-L1 p...
Patent number
12,089,575
Issue date
Sep 17, 2024
REGENERON PHARMACEUTICALS, INC.
Elena Burova
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Rodent animals expressing human CR1
Patent number
12,082,566
Issue date
Sep 10, 2024
REGENERON PHARMACEUTICALS, INC.
Andrew J. Murphy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Anti-PACAP antibodies and uses thereof
Patent number
12,077,581
Issue date
Sep 3, 2024
H. Lundbeck A/S
Maria-Cristina Loomis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods of reducing toxicity induced by Amyloid beta (A-beta) oligo...
Patent number
12,071,472
Issue date
Aug 27, 2024
The University of British Columbia
Neil R. Cashman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
GRP78-binding antibodies and uses thereof and selection of phage-di...
Patent number
12,060,415
Issue date
Aug 13, 2024
Rutgers, The State University of New Jersey
Renata Pasqualini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Treatment for autistic spectrum disorder (ASD) and relevant symptoms
Patent number
12,059,433
Issue date
Aug 13, 2024
Academia Sinica
Yi-Ping Hsueh
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Transgenic mouse model of Neurofibromatosis type 1
Patent number
12,052,979
Issue date
Aug 6, 2024
1. PARIS SCIENCES ET LETTRES—QUARTIER LATIN
Piotr Topilko
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Methods of using humanized FCγR mice to assay Fc regions
Patent number
12,036,288
Issue date
Jul 16, 2024
REGENERON PHARMACEUTICALS, INC.
Lynn MacDonald
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Genetically modified non-human animal with human or chimeric CD3e
Patent number
12,016,315
Issue date
Jun 25, 2024
Biocytogen Pharmaceuticals (Beijing) Co., Ltd
Yuelei Shen
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Animal model for SARS-CoV-2-spike induced coagulopathy
Patent number
12,016,934
Issue date
Jun 25, 2024
The J. David Gladstone Institutes, A Testamentary Trust Established Under The...
Katerina Akassoglou
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Transthyretin antibodies and uses thereof
Patent number
12,006,357
Issue date
Jun 11, 2024
Mor Research Applications Ltd.
Michael Fassler
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for treating and diagnosing blinding eye diseases
Patent number
11,992,534
Issue date
May 28, 2024
Translatum Medicus Inc.
Shelley Romayne Boyd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Screening method for identifying anti-PACAP antibodies or antibody...
Patent number
11,993,648
Issue date
May 28, 2024
H. Lundbeck A/S
Adisa Kuburas
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method for testing ecotoxicity of disinfection by-products
Patent number
11,977,068
Issue date
May 7, 2024
Tongji University
Wenhai Chu
G01 - MEASURING TESTING
Information
Patent Grant
Transgenic C57BL6-BTBR mouse with a humanized MHC II gene that expr...
Patent number
11,974,552
Issue date
May 7, 2024
The University of Toledo
Shahnawaz Imam
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Device for collecting and culturing fish embryos and method for eva...
Patent number
11,969,481
Issue date
Apr 30, 2024
Zhejiang Academy of Agricultural Sciences
Yanhua Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Drug for retinal degenerative disease associated with photoreceptor...
Patent number
11,931,327
Issue date
Mar 19, 2024
Daiichi Sankyo Company, Limited
Naoki Tsuji
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Method of treating osteoarthritis by administering an anti-connexin...
Patent number
11,912,762
Issue date
Feb 27, 2024
Board of Regents of the University of Texas System
Jean X. Jiang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Animal models of corneal ectatic diseases, methods of producing, an...
Patent number
11,895,992
Issue date
Feb 13, 2024
Arturo Solis Herrera
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Anti-polyethylene glycol (PEG) antibody mouse model for rigorous as...
Patent number
11,890,353
Issue date
Feb 6, 2024
Northwestern University
Evan A. Scott
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Method for culturing 3-dimensional lung cancer organoid and method...
Patent number
11,883,508
Issue date
Jan 30, 2024
ONCOCLEW CO., LTD.
Se Jin Jang
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Cas-ready mouse embryonic stem cells and mice and uses thereof
Patent number
11,866,794
Issue date
Jan 9, 2024
REGENERON PHARMACEUTICALS, INC.
Guochun Gong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions for neuromodulation of mosquito feeding behavior and u...
Patent number
11,839,662
Issue date
Dec 12, 2023
University of Central Florida Research Foundation, Inc.
Bradley Jay Willenberg
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information
Patent Grant
Single kidney cell-derived organoids
Patent number
11,834,680
Issue date
Dec 5, 2023
Rutgers, The State University of New Jersey
Hatem Sabaawy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Crnn loss of function rodent model
Patent number
11,825,819
Issue date
Nov 28, 2023
REGENERON PHARMACEUTICALS, INC.
Claudia Gonzaga-Jauregui
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Patents Applications
last 30 patents
Information
Patent Application
ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR
Publication number
20240374761
Publication date
Nov 14, 2024
RADIUS PHARMACEUTICALS, INC.
Beate Klara Maria MANNSTADT
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
GRP78-BINDING ANTIBODIES AND USE THEREOF IN DETECTING OR NEUTRALIZI...
Publication number
20240368258
Publication date
Nov 7, 2024
Rutgers, The State University of New Jersey
Renata PASQUALINI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHAPERONES AS AN AUTOPHAGY RECEPTORS FOR CLEARANCES OF PROTEIN AGGR...
Publication number
20240350586
Publication date
Oct 24, 2024
TSINGHUA UNIVERSITY
Liang GE
G01 - MEASURING TESTING
Information
Patent Application
RODENT ANMALS EXPRESSING HUMAN CR1
Publication number
20240315221
Publication date
Sep 26, 2024
Regeneron Pharmaceuticals, Inc.
Andrew J. MURPHY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR CANCER TREATMENT BY TARGETING AXL SIGN...
Publication number
20240307390
Publication date
Sep 19, 2024
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Charles SPRUCK
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR TREATING CHRONIC LIVER DISEASE AND HEP...
Publication number
20240301417
Publication date
Sep 12, 2024
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Cynthia LEBEAUPIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NON-HUMAN ANIMALS HAVING A HUMANIZED PROGRAMMED CELL DEATH 1 GENE
Publication number
20240298619
Publication date
Sep 12, 2024
Regeneron Pharmaceuticals, Inc.
Elena BUROVA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PEPTIDE FOR TREATING AGE-RELATED MACULAR DEGENERATION
Publication number
20240294610
Publication date
Sep 5, 2024
DAIICHI SANKYO COMPANY, LIMITED
Daisuke Nishimiya
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NME INHIBITORS AND METHODS OF USING NME INHIBITORS
Publication number
20240277803
Publication date
Aug 22, 2024
Minerva Biotechnologies Corporation
Cynthia Bamdad
G01 - MEASURING TESTING
Information
Patent Application
ULTRABRIGHT CHEMILUMINESCENT PROBES FOR DETECTION AND IMAGING
Publication number
20240277873
Publication date
Aug 22, 2024
Nanyang Technological University
Kanyi PU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
POLY-ADP RIBOSE (PAR) TRACKER OPTIMIZED SPLIT-PROTEIN REASSEMBLY PA...
Publication number
20240252689
Publication date
Aug 1, 2024
The Board of Regents of the University of Texas System
W. Lee KRAUS
G01 - MEASURING TESTING
Information
Patent Application
TREATMENT OF NEURODEGENERATIVE DISEASE USING CSA- AND INDY-TYPE COM...
Publication number
20240245806
Publication date
Jul 25, 2024
Brown University
Robbert Creton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC IL1RAP
Publication number
20240224961
Publication date
Jul 11, 2024
Biocytogen JiangSu Co., Ltd.
Xiaofei Zhou
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MODEL OPTIMIZED DRUG AND DRUG COMBINATIONS FOR TREATING CANCERS
Publication number
20240216546
Publication date
Jul 4, 2024
My Personal Therapeutics
Santiago Nahuel Villegas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Artemisia anti-bacterial compositions and methods of use for inhibi...
Publication number
20240207219
Publication date
Jun 27, 2024
Worcester Polytechnic Institute
Scarlet S. Shell
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NEURO-BEHAVIORAL ASSAY FOR PHYSIOLOGICAL EVALUATION OF WATER-SOLUBL...
Publication number
20240207454
Publication date
Jun 27, 2024
Northeastern University
Gunther Zupanc
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Method for Constructing Murine Model with Mutations in Csf1r Gene a...
Publication number
20240206441
Publication date
Jun 27, 2024
BEIJING TIANTAN HOSPITAL, CAPITAL MEDICAL UNIVERSITY
Jun XU
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
METHODS FOR IN VIVO DELIVERY OF MICROBES TO HUMAN MICROENVIRONMENTS
Publication number
20240189458
Publication date
Jun 13, 2024
William Marsh Rice University
Jeffrey TABOR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DRUG FOR RETINAL DEGENERATIVE DISEASE ASSOCIATED WITH PHOTORECEPTOR...
Publication number
20240139134
Publication date
May 2, 2024
DAIICHI SANKYO COMPANY, LIMITED
Naoki Tsuji
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Combination therapy for the treatment or prevention of neurological...
Publication number
20240115581
Publication date
Apr 11, 2024
NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU)
Christiana Bjorkli
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD FOR CULTURING 3-DIMENSIONAL LUNG CANCER ORGANOID AND METHOD...
Publication number
20240108762
Publication date
Apr 4, 2024
ONCOCLEW CO., LTD.
Se Jin JANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS, METHODS, MODELS AND USES FOR SIMIAN VARICELLA VIRUS (...
Publication number
20240091386
Publication date
Mar 21, 2024
The Regents of the University of Colorado, a Body Corporate
Ravi Mahalingam
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CAS-READY MOUSE EMBRYONIC STEM CELLS AND MICE AND USES THEREOF
Publication number
20240093316
Publication date
Mar 21, 2024
Regeneron Pharmaceuticals, Inc.
Guochun Gong
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC FCRN
Publication number
20240081301
Publication date
Mar 14, 2024
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
Chengzhang Shang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITION AND USE THEREOF
Publication number
20240082432
Publication date
Mar 14, 2024
Debin CUI
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
MODEL OF SPINAL CORD HYPOPERFUSION AND ISCHEMIC STROKE WITH IMMEDIA...
Publication number
20240075169
Publication date
Mar 7, 2024
Ohio State Innovation Foundation
Hesham Kelani
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
Publication number
20240074414
Publication date
Mar 7, 2024
Regeneron Pharmaceuticals, Inc.
Andrew J. Murphy
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
APPLICATION OF HELZ2 IN DRUGS FOR PREVENTING AND TREATING TUMORS
Publication number
20230416749
Publication date
Dec 28, 2023
JIANGSU CONCORD BIOTECHNOLOGY CO., LTD
Huabiao CHEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES
Publication number
20230405152
Publication date
Dec 21, 2023
Translatum Medicus Inc.
Shelley Romayne Boyd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Methods for Treating Conditions Associated with MASP-2 Dependent Co...
Publication number
20230391889
Publication date
Dec 7, 2023
University of Leicester
Hans-Wilhelm Schwaeble
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING