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Sphingomyelin phosphodiesterase (3.1.4.12)
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C12Y301/04012
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C12
Biochemistry
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C12Y301/00
Hydrolases acting on ester bonds (3.1)
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C12Y301/04012
Sphingomyelin phosphodiesterase (3.1.4.12)
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Patents Grants
last 30 patents
Information
Patent Grant
Compositions for treating ectopic calcification disorders, and meth...
Patent number
12,234,489
Issue date
Feb 25, 2025
Yale University
Demetrios Braddock
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the treatment of steatosis-associated...
Patent number
12,171,731
Issue date
Dec 24, 2024
Duke University
Dwight D. Koeberl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the treatment of cytoplasmic glycogen...
Patent number
12,036,190
Issue date
Jul 16, 2024
Duke University
Priya Kishnani
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for activating signaling through the CB1 c...
Patent number
12,023,332
Issue date
Jul 2, 2024
Wylder Nation Foundation
Maria Dolores Ledesma
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of treating acid sphingomyelinase deficiency
Patent number
11,998,592
Issue date
Jun 4, 2024
Genzyme Corporation
Wei-Lien Chuang
G01 - MEASURING TESTING
Information
Patent Grant
Fusion proteins comprising enzyme replacement therapy enzymes
Patent number
11,866,742
Issue date
Jan 9, 2024
Denali Therapeutics Inc.
Anastasia Henry
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA preparations comprising purified modified RNA for reprogramming...
Patent number
11,739,300
Issue date
Aug 29, 2023
Katalin Kariko
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for the treatment of steatosis-associated...
Patent number
11,690,812
Issue date
Jul 4, 2023
Duke University
Dwight D. Koeberl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and pharmaceutical compositions for enhancing CD8+ T cell-d...
Patent number
11,078,277
Issue date
Aug 3, 2021
INSERM (Institut National de la Sante et de la Recherche Medicale)
Thierry Levade
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA preparations comprising purified modified RNA for reprogramming...
Patent number
11,028,370
Issue date
Jun 8, 2021
Katalin Kariko
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods and compositions for the treatment of steatosis-associated...
Patent number
10,940,125
Issue date
Mar 9, 2021
Duke University
Dwight D. Koeberl
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Gene therapy for neurometabolic disorders
Patent number
10,913,956
Issue date
Feb 9, 2021
Genzyme Corporation
Marco A. Passini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligosaccharides comprising an aminooxy group and conjugates thereof
Patent number
10,907,142
Issue date
Feb 2, 2021
Genzyme Corporation
Yunxiang Zhu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Marker for acid sphingomyelinase disorders and uses thereof
Patent number
10,888,607
Issue date
Jan 12, 2021
Genzyme Corporation
Wei-Lien Chuang
G01 - MEASURING TESTING
Information
Patent Grant
Fusion proteins comprising enzyme replacement therapy enzymes
Patent number
10,870,837
Issue date
Dec 22, 2020
Denali Therapeutics Inc.
Anastasia Henry
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method for treating a degenerative neurological disorders comprisin...
Patent number
10,682,373
Issue date
Jun 16, 2020
Kyungpook National University Industry-Academic Cooperation Foundation
Jae Sung Bae
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Dose escalation enzyme replacement therapy for treating acid sphing...
Patent number
10,188,705
Issue date
Jan 29, 2019
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Composition comprising ASM inhibitor as active ingredient for preve...
Patent number
10,098,855
Issue date
Oct 16, 2018
Kyungpook National University Industry-Academic Cooperation Foundation
Jae Sung Bae
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Intraventricular enzyme delivery for lysosomal storage diseases
Patent number
10,080,783
Issue date
Sep 25, 2018
Genzyme Corporation
James Dodge
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Marker for acid sphingomyelinase disorders and uses thereof
Patent number
10,022,428
Issue date
Jul 17, 2018
Genzyme Corporation
Wei-Lien Chuang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RNA preparations comprising purified modified RNA for reprogramming...
Patent number
10,006,007
Issue date
Jun 26, 2018
The Trustees of the University of Pennsylvania
Katalin Kariko
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Targeted protein replacement for the treatment of lysosomal storage...
Patent number
9,655,953
Issue date
May 23, 2017
Icahn School of Medicine at Mount Sinai
Silvia Muro Galindo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Dose escalation enzyme replacement therapy for treating acid sphing...
Patent number
9,655,954
Issue date
May 23, 2017
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligosaccharides comprising an aminooxy group and conjugates thereof
Patent number
9,469,850
Issue date
Oct 18, 2016
Genzyme Corporation
Yunxiang Zhu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions comprising alkaline sphingomyelinases for use as a die...
Patent number
9,439,953
Issue date
Sep 13, 2016
VSL PHARMACUETICALS, INC.
Claudio De Simone
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Dose escalation enzyme replacement therapy for treating acid sphing...
Patent number
9,114,139
Issue date
Aug 25, 2015
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antisense oligonucleotides against neutral sphingomyelinase and neu...
Patent number
9,006,205
Issue date
Apr 14, 2015
Rush University Medical Center
Kalipada Pahan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Intraventricular enzyme delivery for lysosomal storage diseases
Patent number
8,926,967
Issue date
Jan 6, 2015
Genzyme Corporation
James Dodge
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligosaccharides comprising an aminooxy group and conjugates thereof
Patent number
8,759,501
Issue date
Jun 24, 2014
Genzyme Corporation
Yunxiang Zhu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Dose escalation enzyme replacement therapy for treating acid sphing...
Patent number
8,709,408
Issue date
Apr 29, 2014
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
COMPOSITIONS AND METHODS FOR ACTIVATING SIGNALING THROUGH THE CB1 C...
Publication number
20250057838
Publication date
Feb 20, 2025
Wylder Nation Foundation
Maria Dolores LEDESMA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTI-TFR:ACID SPHINGOMYELINASE FOR TREATMENT OF ACID SPHINGOMYELINA...
Publication number
20250049896
Publication date
Feb 13, 2025
Regeneron Pharmaceuticals, Inc.
Maria Praggastis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MARKER FOR ACID SPHINGOMYELINASE DISORDERS AND USES THEREOF
Publication number
20240398907
Publication date
Dec 5, 2024
Genzyme Corporation
Wei-Lien CHUANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Methods and Compositions for the Treatment of Cytoplasmic Glycogen...
Publication number
20240398729
Publication date
Dec 5, 2024
DUKE UNIVERSITY
Priya Kishnani
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION
Publication number
20240148699
Publication date
May 9, 2024
OTSUKA PHARMACEUTICAL CO., LTD.
Minoru OKADA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATMENT OF NIEMANN PICK TYPE A DISEASE
Publication number
20240115733
Publication date
Apr 11, 2024
The Trustees of the University of Pennsylvania
James M. WILSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Pharmaceutical Recombinant Human Acid Sphingomyelinase Compositions...
Publication number
20230365946
Publication date
Nov 16, 2023
Genzyme Corporation
Thomas M. Wasylenko
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
Methods and Compositions for the Treatment of Steatosis-Associated...
Publication number
20230285328
Publication date
Sep 14, 2023
DUKE UNIVERSITY
Dwight D. Koeberl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Methods and Compositions for the Treatment of Steatosis-Associated...
Publication number
20230285329
Publication date
Sep 14, 2023
DUKE UNIVERSITY
Dwight D. Koeberl
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
USE OF RECOMBINANT HUMAN ACID SPHINGOMYELINASE TO IMPROVE SKELETAL...
Publication number
20230226221
Publication date
Jul 20, 2023
Children's National Medical Center
Jyoti K. Jaiswal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHING...
Publication number
20220305091
Publication date
Sep 29, 2022
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TREATMENT AND PREVENTION OF AGING RELATED-DISEASE AND/OR AGING BY T...
Publication number
20220288004
Publication date
Sep 15, 2022
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Pirkka-Pekka LAURILA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION
Publication number
20220265613
Publication date
Aug 25, 2022
OTSUKA PHARMACEUTICAL CO., LTD.
Minoru OKADA
C07 - ORGANIC CHEMISTRY
Information
Patent Application
OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF
Publication number
20220204963
Publication date
Jun 30, 2022
Genzyme Corporation
Yunxiang Zhu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Methods and Compositions for the Treatment of Cytoplasmic Glycogen...
Publication number
20220040126
Publication date
Feb 10, 2022
DUKE UNIVERSITY
Priya Kishnani
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Methods and Compositions for the Treatment of Steatosis-Associated...
Publication number
20210251922
Publication date
Aug 19, 2021
DUKE UNIVERSITY
Dwight D. Koeberl
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INTRAVENTRICULAR ENZYME DELIVERY FOR LYSOSOMAL STORAGE DISEASES
Publication number
20210228692
Publication date
Jul 29, 2021
Genzyme Corporation
James DODGE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES
Publication number
20210198640
Publication date
Jul 1, 2021
Denali Therapeutics Inc.
Giuseppe ASTARITA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MARKER FOR ACID SPHINGOMYELINASE DISORDERS AND USES THEREOF
Publication number
20210162021
Publication date
Jun 3, 2021
Genzyme Corporation
Wei-Lien CHUANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR ACTIVATING SIGNALING THROUGH THE CB1 C...
Publication number
20210085678
Publication date
Mar 25, 2021
Wylder Nation Foundation
Maria Dolores LEDESMA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHING...
Publication number
20210077593
Publication date
Mar 18, 2021
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR TUMOR RADIOSENSITIZATION
Publication number
20210069330
Publication date
Mar 11, 2021
Memorial Sloan-Kettering Cancer Center
Richard N. KOLESNICK
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Compositions for Treating Ectopic Calcification Disorders, and Meth...
Publication number
20210032610
Publication date
Feb 4, 2021
Yale University
Demetrios BRADDOCK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA PREPARATIONS COMPRISING PURIFIED MODIFIED RNA FOR REPROGRAMMING...
Publication number
20210024895
Publication date
Jan 28, 2021
The Trustees of the University of Pennsylvania
Katalin Kariko
C07 - ORGANIC CHEMISTRY
Information
Patent Application
FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES
Publication number
20200277584
Publication date
Sep 3, 2020
Denali Therapeutics Inc.
Giuseppe ASTARITA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION
Publication number
20200078340
Publication date
Mar 12, 2020
OTSUKA PHARMACEUTICAL CO., LTD.
Minoru OKADA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF
Publication number
20200010825
Publication date
Jan 9, 2020
Genzyme Corporation
Yunxiang Zhu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHING...
Publication number
20190151419
Publication date
May 23, 2019
Icahn School of Medicine at Mount Sinai
Edward H. Schuchman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INTRAVENTRICULAR ENZYME DELIVERY FOR LYSOSOMAL STORAGE DISEASES
Publication number
20190083582
Publication date
Mar 21, 2019
Genzyme Corporation
James DODGE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION
Publication number
20190070151
Publication date
Mar 7, 2019
OTSUKA PHARMACEUTICAL CO., LTD.
Minoru OKADA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...