Virus like particles [VLP]

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CPC
C12N2710/20023

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2710/00dsDNA Viruses

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C12N2710/20023Virus like particles [VLP]

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Universal vaccine platform
- Patent number 12,257,302
- Issue date Mar 25, 2025
- Arizona Board of Regents on behalf of Arizona State University
- Hugh Mason
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus-like particle conjugates
- Patent number 12,239,697
- Issue date Mar 4, 2025
- Inventprise, Inc.
- Subhash V. Kapre
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric papilloma virus L1 protein
- Patent number 12,139,514
- Issue date Nov 12, 2024
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus-like particle conjugates for diagnosis and treatment of tumors
- Patent number 12,029,794
- Issue date Jul 9, 2024
- Biosciences, Inc.
- Elisabet de los Pinos
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric virus-like particles and uses thereof as antigen-specific...
- Patent number 11,944,677
- Issue date Apr 2, 2024
- VERIMMUNE INC.
- Joshua Weiyuan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Non-human papillomaviruses for gene delivery in vitro and in vivo
- Patent number 11,946,048
- Issue date Apr 2, 2024
- Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.
- Thomas Grunwald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Universal vaccine platform
- Patent number 11,865,174
- Issue date Jan 9, 2024
- Arizona Board of Regents on behalf of Arizona State University
- Hugh Mason
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus-like particle conjugates for diagnosis and treatment of tumors
- Patent number 11,806,406
- Issue date Nov 7, 2023
- Aura Biosciences, Inc.
- Elisabet de los Pinos
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mutant of L1 protein of human papillomavirus type 18
- Patent number 11,771,754
- Issue date Oct 3, 2023
- Xiamen University
- Shaowei Li
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
HPV vaccine
- Patent number 11,638,754
- Issue date May 2, 2023
- Merck Sharp & Dohme LLC
- Andrew J. Bett
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conjugated virus-like particles and uses thereof as anti-tumor immu...
- Patent number 11,560,408
- Issue date Jan 24, 2023
- VERIMMUNE INC.
- Joshua Weiyuan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Serologic test for therapy control of HPV16 positive carcinoma
- Patent number 11,506,667
- Issue date Nov 22, 2022
- ABVIRIS DEUTSCHLAND GMBH
- Ralf Hilfrich
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Mutant of L1 protein of human papillomavirus type 39
- Patent number 11,427,618
- Issue date Aug 30, 2022
- XIAMEN UNIVERSITRY
- Shaowei Li
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus-like particle conjugates
- Patent number 11,389,519
- Issue date Jul 19, 2022
- Inventprise, LLC
- Subhash V. Kapre
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chimeric virus-like particles and uses thereof as antigen-specific...
- Patent number 11,285,203
- Issue date Mar 29, 2022
- VERIMMUNE INC.
- Joshua Weiyuan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Virus like particle with efficient epitope display
- Patent number 11,129,882
- Issue date Sep 28, 2021
- University of Copenhagen
- Adam Frederik Sander Bertelsen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Virus-like particle conjugates for diagnosis and treatment of tumors
- Patent number 11,110,181
- Issue date Sep 7, 2021
- Aura Biosciences, Inc.
- Elisabet de los Pinos
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Universal vaccine platform
- Patent number 11,058,766
- Issue date Jul 13, 2021
- Arizona Board of Regents on behalf of Arizona State University
- Hugh Mason
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Virus-like particle compositions and vaccines against epstein-barr...
- Patent number 10,960,072
- Issue date Mar 30, 2021
- The University of Massachusetts
- Javier Gordon Ogembo
- G01 - MEASURING TESTING
Information Patent Grant
Mutant of L1 protein of human papillomavirus type 58
- Patent number 10,940,194
- Issue date Mar 9, 2021
- Xiamen University
- Shaowei Li
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Serologic test for therapy control of HPV16 positive carcinoma
- Patent number 10,852,303
- Issue date Dec 1, 2020
- ABVIRIS DEUTSCHLAND GMBH
- Ralf Hilfrich
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Papillomavirus pseudoviruses for detection and therapy of tumors
- Patent number 10,814,014
- Issue date Oct 27, 2020
- The USA, as represented by the Secretary, Dept. of Health and Human Services
- Jeffrey Roberts
- B82 - NANO-TECHNOLOGY
Information Patent Grant
HPV vaccine formulations comprising aluminum adjuvant and methods o...
- Patent number 10,772,947
- Issue date Sep 15, 2020
- Merck Sharp & Dohme Corp.
- Ramesh V. Chintala
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Inflammasome activators and methods of use to treat tumors
- Patent number 10,751,398
- Issue date Aug 25, 2020
- Loyola University Chicago
- Liang Qiao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
HPV particles and uses thereof
- Patent number 10,688,172
- Issue date Jun 23, 2020
- INSERM (Institut National de la Sante et de la Recherche Medicale)
- Pierre L. Coursaget
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Virus-like particle conjugates for diagnosis and treatment of tumors
- Patent number 10,588,984
- Issue date Mar 17, 2020
- Aura Biosciences, Inc.
- Elisabet de los Pinos
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Truncated L1 protein of human papillomavirus type 11
- Patent number 10,537,629
- Issue date Jan 21, 2020
- Xiamen University
- Jun Zhang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Mutant of L1 protein of human papillomavirus type 11
- Patent number 10,513,541
- Issue date Dec 24, 2019
- Xiamen University
- Shaowei Li
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Microneedle-based transdermal delivery system and method of making...
- Patent number 10,463,608
- Issue date Nov 5, 2019
- The Corporation of Mercer University
- Martin J. D'Souza
- B29 - WORKING OF PLASTICS WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
Information Patent Grant
Virus-like particle compositions and vaccines against Epstein-Barr...
- Patent number 10,314,906
- Issue date Jun 11, 2019
- University of Massachusetts
- Javier Gordon Ogembo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
CONTROLLED RELEASE VACCINE FORMULATIONS
- Publication number 20250205328
- Publication date Jun 26, 2025
- Merck Sharp & Dohme LLC
- Akhilesh Bhambhani
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Virus-Like Particle Conjugates
- Publication number 20250186569
- Publication date Jun 12, 2025
- Inventprise, Inc.
- Subhash V. Kapre
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250171506
- Publication date May 29, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250145672
- Publication date May 8, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250145671
- Publication date May 8, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250136644
- Publication date May 1, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250136645
- Publication date May 1, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250136646
- Publication date May 1, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250122245
- Publication date Apr 17, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250122246
- Publication date Apr 17, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250109174
- Publication date Apr 3, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250101068
- Publication date Mar 27, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CHIMERIC PAPILLOMAVIRUS L1 PROTEIN
- Publication number 20250092096
- Publication date Mar 20, 2025
- SinoCellTech Ltd.
- Liangzhi Xie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NANOEMULSION ADJUVANT COMPOSITIONS FOR HUMAN PAPILLOMAVIRUS VACCINES
- Publication number 20240408188
- Publication date Dec 12, 2024
- Merck Sharp & Dohme LLC
- Patrick L. Ahl
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...
- Publication number 20240390473
- Publication date Nov 28, 2024
- VERIMMUNE INC.
- Joshua Weiyuan WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HUMAN PAPILLOMAVIRUS TYPE 18 CHIMERIC PROTEIN AND USE THEREOF
- Publication number 20240317808
- Publication date Sep 26, 2024
- INSTITUTE OF BASIC MEDICAL SCIENCES, CHINESE ACADEMY OF MEDICAL SCIENCES
- Xuemei Xu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
UNIVERSAL VACCINE PLATFORM
- Publication number 20240216502
- Publication date Jul 4, 2024
- Arizona Board of Regents on behalf of Arizona State University
- Hugh Mason
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VIRUS-LIKE PARTICLE CONJUGATES FOR DIAGNOSIS AND TREATMENT OF TUMORS
- Publication number 20240216527
- Publication date Jul 4, 2024
- Aura Biosciences, Inc.
- Elisabet de los Pinos
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MODIFIED HUMAN PAPILLOMAVIRUS TYPE 52 L1 PROTEIN AND USE THEREOF
- Publication number 20240002447
- Publication date Jan 4, 2024
- INSTITUTE OF BASIC MEDICAL SCIENCES, CHINESE ACADEMY OF MEDICAL SCIENCES
- Xuemei Xu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONJUGATED VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTI-TUMOR IMMU...
- Publication number 20230391830
- Publication date Dec 7, 2023
- VERIMMUNE INC.
- Joshua Weiyuan WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Virus-Like Particle Conjugates
- Publication number 20230093700
- Publication date Mar 23, 2023
- Inventprise, LLC
- Subhash V. Kapre
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Chimeric Papilloma Virus L1 Protein
- Publication number 20220281925
- Publication date Sep 8, 2022
- SinoCellTech Ltd.
- Liangzhi Xie
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR THE EXPANSION OF HPV IMMUNOGEN SPECIFIC T-CELLS
- Publication number 20220226457
- Publication date Jul 21, 2022
- NEOGAP THERAPEUTICS AB
- Hans GRONLUND
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...
- Publication number 20220226460
- Publication date Jul 21, 2022
- VERIMMUNE INC.
- Joshua Weiyuan WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
UNIVERSAL VACCINE PLATFORM
- Publication number 20210330785
- Publication date Oct 28, 2021
- Arizona Board of Regents on behalf of Arizona State University
- Hugh Mason
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MUTANT OF L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 18
- Publication number 20210228703
- Publication date Jul 29, 2021
- XIAMEN UNIVERSITY
- Shaowei LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Mutant of L1 Protein of Human Papillomavirus Type 39
- Publication number 20210198322
- Publication date Jul 1, 2021
- XIAMEN UNIVERSITY
- Shaowei LI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SEROLOGIC TEST FOR THERAPY CONTROL OF HPV16 POSITIVE CARCINOMA
- Publication number 20200408768
- Publication date Dec 31, 2020
- Abviris Deutschland GmbH
- Ralf Hilfrich
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Non-human papillomaviruses for gene delivery in vitro and in vivo
- Publication number 20200385718
- Publication date Dec 10, 2020
- Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.
- Thomas GRUNWALD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONJUGATED VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTI-TUMOR IMMU...
- Publication number 20200291072
- Publication date Sep 17, 2020
- VERIMMUNE INC.
- Joshua Weiyuan WANG
- C07 - ORGANIC CHEMISTRY

Virus like particles [VLP]

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Universal vaccine platform

Virus-like particle conjugates

Chimeric papilloma virus L1 protein

Virus-like particle conjugates for diagnosis and treatment of tumors

Chimeric virus-like particles and uses thereof as antigen-specific...

Non-human papillomaviruses for gene delivery in vitro and in vivo

Universal vaccine platform

Virus-like particle conjugates for diagnosis and treatment of tumors

Mutant of L1 protein of human papillomavirus type 18

HPV vaccine

Conjugated virus-like particles and uses thereof as anti-tumor immu...

Serologic test for therapy control of HPV16 positive carcinoma

Mutant of L1 protein of human papillomavirus type 39

Virus-like particle conjugates

Chimeric virus-like particles and uses thereof as antigen-specific...

Virus like particle with efficient epitope display

Virus-like particle conjugates for diagnosis and treatment of tumors

Universal vaccine platform

Virus-like particle compositions and vaccines against epstein-barr...

Mutant of L1 protein of human papillomavirus type 58

Serologic test for therapy control of HPV16 positive carcinoma

Papillomavirus pseudoviruses for detection and therapy of tumors

HPV vaccine formulations comprising aluminum adjuvant and methods o...

Inflammasome activators and methods of use to treat tumors

HPV particles and uses thereof

Virus-like particle conjugates for diagnosis and treatment of tumors

Truncated L1 protein of human papillomavirus type 11

Mutant of L1 protein of human papillomavirus type 11

Microneedle-based transdermal delivery system and method of making...

Virus-like particle compositions and vaccines against Epstein-Barr...

Patents Applicationslast 30 patents

CONTROLLED RELEASE VACCINE FORMULATIONS

Virus-Like Particle Conjugates

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

CHIMERIC PAPILLOMAVIRUS L1 PROTEIN

NANOEMULSION ADJUVANT COMPOSITIONS FOR HUMAN PAPILLOMAVIRUS VACCINES

CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...

HUMAN PAPILLOMAVIRUS TYPE 18 CHIMERIC PROTEIN AND USE THEREOF

UNIVERSAL VACCINE PLATFORM

VIRUS-LIKE PARTICLE CONJUGATES FOR DIAGNOSIS AND TREATMENT OF TUMORS

MODIFIED HUMAN PAPILLOMAVIRUS TYPE 52 L1 PROTEIN AND USE THEREOF

CONJUGATED VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTI-TUMOR IMMU...

Virus-Like Particle Conjugates

Chimeric Papilloma Virus L1 Protein

METHOD FOR THE EXPANSION OF HPV IMMUNOGEN SPECIFIC T-CELLS

CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...

UNIVERSAL VACCINE PLATFORM

MUTANT OF L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 18

Mutant of L1 Protein of Human Papillomavirus Type 39

SEROLOGIC TEST FOR THERAPY CONTROL OF HPV16 POSITIVE CARCINOMA

Non-human papillomaviruses for gene delivery in vitro and in vivo

CONJUGATED VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTI-TUMOR IMMU...