Claims
- 1. A antibody or antigen-binding fragment thereof capable of specifically binding to the amino acid sequence (SEQ ID NO: 4) shown in FIG. 2 for AL-1.
- 2. The antibody of claim 1 that is a monoclonal antibody.
- 3. The antibody or antigen-binding fragment of claim 1 that is a human antibody or fragment thereof.
- 4. The antibody or antibody-binding fragment of claim 1 labeled with a detectable moiety.
- 5. The antibody or antigen-binding fragment of claim 1, wherein AL-1 is in its native confirmation.
- 6. The antibody or antigen-binding fragment of claim 1 that is a chimeric antibody or antigen-binding fragment.
- 7. The antibody or antigen-binding fragment of claim 1 which is capable of substantially inhibiting or eliminating the functional activity of AL-1.
- 8. The antibody or antigen-binding fragment of claim 1 that is humanized.
- 9. The antibody or antigen-binding fragment of claim 1 that binds AL-1 with an affinity of at least about 10.sup.6 L/mole.
Parent Case Info
This is a continuation of co-pending application Ser. No. 08/330,128 filed on Oct. 27, 1994which application is incorporated herein by reference and to which application priority is claimed under 35 USC .sctn. 120.
Foreign Referenced Citations (1)
Number |
Date |
Country |
597503 A2 |
May 1994 |
EPX |
Continuations (1)
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Number |
Date |
Country |
Parent |
330128 |
Oct 1994 |
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