Claims
- 1. A beta amyloid binding peptide comprising a sequence selected from the group consisting of
- 2. A beta amyloid binding peptide as in claim 1 comprising a sequence selected from the group consisting of:
- 3. A beta amyloid binding peptide as in claim 2 comprising a sequence selected from the group consisting of:
- 4. The peptide of claim 1 wherein the peptide contains at least one D-isomeric amino acid residue.
- 5. A fusion protein comprising the β amyloid binding peptide of claim 1 operably linked to another sequence.
- 6. A method comprising the steps:
(a) contacting a β amyloid peptide with a β amyloid binding peptide of claim 1, and a putitive inhibitory compound for sufficient time to provide a β amyloid/binding peptide complex; and (b) measuring a change in quantity of β amyloid/binding peptide complex.
- 7. A diagnostic method comprising the steps:
(a) contacting a biological sample with a β amyloid binding peptide of claim 1 thereby allowing interaction of a beta amyloid peptide with the binding peptide to form a beta amyloid peptide/binding peptide complex; (b) isolating the β amyloid peptide/binding peptide complex; and (c) detecting the β amyloid peptide.
- 8. A diagnostic method comprising the steps:
(a) contacting a biological sample with a β amyloid affinity capture reagent thereby allowing interaction of a beta amyloid peptide with the affinity capture reagent to form a beta amyloid peptide/affinity capture complex; (b) isolating the amyloid peptide/affinity capture complex; and (c) detecting the β amyloid peptide with a labeled β amyloid binding peptide of claim 1.
CROSS REFERENCE OF RELATED APPLICATIONS
[0001] This application claims priority from U.S. provisional application Serial No. 60/225,048, filed Aug. 14, 2000, which is hereby incorporated by reference.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60225048 |
Aug 2000 |
US |