CA125 GENE AND ITS USE FOR DIAGNOSTIC AND THERAPEUTIC INTERVENTIONS

Information

  • Patent Application
  • 20170305980
  • Publication Number
    20170305980
  • Date Filed
    January 30, 2017
    7 years ago
  • Date Published
    October 26, 2017
    7 years ago
Abstract
The CA125 gene has been cloned and multiple repeat sequences as well as the carboxy terminus have been identified. The CA125 molecule comprises three major domains: an extracellular amino terminal domain (Domain 1); a large multiple repeat domain (Domain 2); and a carboxy terminal domain (Domain 3) which includes a transmembrane anchor with a short cytoplasmic domain. The amino terminal domain is dominated by its capacity for O-glycosylation and its resultant richness in serine and threonine residues. An amino terminal extension is presented, which comprises four genomic exons. The molecular structure is dominated by a repeat domain comprising 156 amino acid repeat units, which encompass the epitope binding sites. More than 60 repeat units have been identified, sequenced, and contiguously placed in the CA125 domain structure. More specifically, this invention is directed to a CA125 cDNA sequence which can be introduced into animal or human cells to achieve transcription or expression of the cDNA.
Description
BACKGROUND OF THE INVENTION

The present invention relates generally to the cloning, identification, and expression of the CA125 gene's glycosylated amino terminal domain, the multiple repeat domain, and the carboxy terminal domain in vitro and, more specifically, to the use of recombinant CA125 with epitope binding sites for diagnostic and therapeutic purposes. Additionally, the genomic DNA, a molecule encoding a 5′ upstream region of CA125 and a genomic DNA sequence for the amino terminal, extra cellular repeats and carboxy terminal of CA125 has been determined.


CA125 is an antigenic determinant located on the surface of ovarian carcinoma cells with essentially no expression in normal adult ovarian tissue. Elevated in the sera of patients with ovarian adenocarcinoma, CA125 has played a critical role for more than 15 years in the management of these patients relative to their response to therapy and also as an indicator of recurrent disease.


It is well established that CA125 is not uniquely expressed in ovarian carcinoma, but is also found in both normal secretory tissues and other carcinomas (i.e., pancreas, liver, colon) [Hardardottir H et al., Distribution of CA125 in embryonic tissue and adult derivatives of the fetal periderm, Am J Obstet. Gynecol. 163; 6(1):1925-1931 (1990); Zurawski V R et al., Tissue distribution and characteristics of the CA125 antigen, Cancer Rev. 11-12:102-108 (1988); and O'Brien T J et al., CA125 antigen in human amniotic fluid and fetal membranes, Am J Obstet Gynecol. 155:50-55, (1986); Nap M et al., Immunohistochemical characterization of 22 monoclonal antibodies against the CA125 antigen: 2nd report from the ISOBM TD-1 workshop, Tumor Biology 17:325-332 (1996)]. Notwithstanding, CA125 correlates directly with the disease status of affected patients (i.e., progression, regression, and no change), and has become the “gold standard” for monitoring patients with ovarian carcinoma [Bast R C et al., A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer, N Engl J Med. 309:883-887 (1983); and Bon G C et al., Serum tumor marker immunoassays in gynecologic oncology: Establishment of reference values, Am J Obstet. Gynecol. 174:107-114 (1996)]. CA125 is especially useful in post-menopausal patients where endometrial tissue has become atrophic and, as a result, is not a major source of normal circulating CA125.


During the mid 1980's, the inventor of the present invention and others developed M11, a monoclonal antibody to CA125. M11 binds to a dominant epitope on the repeat structure of the CA125 molecule [O'Brien T J et al., New monoclonal antibodies identify the glycoprotein carrying the CA125 epitope, Am J Obstet Gynecol 165:1857-64 (1991)]. More recently, the inventor and others developed a purification and stabilization scheme for CA125, which allows for the accumulation of highly purified high molecular weight CA125 [O'Brien T J et al., More than 15 years of CA125: What is known about the antigen, its structure and its function, Int J Biological Markers 13(4):188-195 (1998)].


Considerable progress has been made over the years to further characterize the CA125 molecule, its structure and its function. The CA125 molecule is a high molecular weight glycoprotein with a predominance of O-linked sugar side chains. The native molecule exists as a very large complex (˜2-5 million daltons). The complex appears to be composed of an epitope containing CA125 molecule and binding proteins which carry no CA125 epitopes. The CA125 molecule is heterogenous in both size and charge, most likely due to continuous deglycosylation of the side chains during its life-span in bodily fluids. The core CA125 subunit is in excess of 200,000 daltons, and retains the capacity to bind both OC125 and M11 class antibodies.


Despite the advances in detection and quantitation of serum tumor markers like CA125, the majority of ovarian cancer patients are still diagnosed at an advanced stage of the disease—Stage III or IV. Further, the management of patients' responses to treatment and the detection of disease recurrence remain major problems. There, thus, remains a need to significantly improve and standardize current CA125 assay systems. Further, the development of an early indicator of risk of ovarian cancer will provide a useful tool for early diagnosis and improved prognosis.


SUMMARY OF THE INVENTION

Thus, it is an object of the present invention to provide a recombinant CA125 cDNA molecule which can be introduced into animals or human cells to achieve transcription or -expression of the cDNA. The utility of knowing the DNA sequence of a specific gene is that a recombinant protein can be produced which can be used as an easily renewable source of that gene or a portion of the gene. Producing and purifying recombinant protein is easier and can produce greater quantities of protein than purifying native protein from patients. The recombinant protein can then be used to produce antibodies to the gene, both polyclonal and monoclonal. The recombinant protein can also be used as a positive control in test kits and experiments.


The genomic sequence for CA125 and a 5′ upstream region has been determined. A DNA sequence showing the 5′ upstream region and the amino terminal portion of the CA125 molecule is set out in Table 1 and SEQ ID NO: 1. The extracellular amino terminal domain is made of exons: Exon 1 from 2205-11679; Exon 2 from 13464-13570; Exon 3 from 16177-34419; Exon 4 from 34575-38024; Exon 5 from 38689-38800; Exon 6 from 40578-45257; Exon 7 from 47360-47395; Exon 8 from 52407-52442; Exon 9 from 52686-52744 as set out in SEQ ID NO: 1. A DNA sequence showing the extracellular repeat portion of the CA125 molecule is set out in Table 2 and SEQ ID NO: 2. The genomic repeats are made of exons: Exon R1 from 1-130; Exon R2 from 442-510; Exon R3 from 5479-5652; Exon R4 from 6301-6334; Exon R5 from 6593-6657; Exon R1 from 7558-7683; Exon R2 from 8216-8284; Exon R3 from 8877-9050; Exon R4 from 9380-9413; Exon R5 from 9675-9739; Exon R1 from 10201-10291; Exon R2 from 10524-10592; Exon R3 from 11200-11373; Exon R4 from 11722-11755; Exon R5 from 12016-12036; Exon R1 from 12169-12295; Exon R2 from 12532-12600; Exon R3 from 13219-13392; Exon R4 from 13723-13756; Exon R5 from 14016-14077; Exon R1 from 15001-15126; Exon R2 from 15367-15435; Exon R1 from 15648-15773; Exon R2 from 16002-16070; Exon R3 from 16653-16826; Exon R4 from 17158-17191; Exon R5 from 17453-17517; Exon R1 from 18532-18657; Exon R2 from 18888-18956; Exon R3 from 19633-19806; Exon R4 from 20141-20176; Exon R5 from 20387-20449; Exon R1 from 21609-21731; Exon R2 from 21940-22008; Exon R3 from 22605-22778; Exon R4 from 23109-23142; Exon R1 from 29046-29168; Exon R2 from 29266-29334; Exon R3 from 33917-34090; Exon R4 from 36702-36734; Exon R5 from 38270-38320; Exon R1 from 39104-39224; Exon R2 from 39315-39383; Exon R3 from 39532-39705; Exon R4 from 41862-41992. A DNA sequence showing the carboxy terminal domain of the CA125 molecule is set out in Table 3 and SEQ ID NO: 3. The carboxy terminal portion is made of exons: Exon C1 from 1-66; Exon C2 from 1802-1947; Exon C3 from 4198-4350; Exon C4, from 4679-4747; Exon C5 from 6811-6978; Exon C6 from 11232-11270; Exon C7 from 11594-11677; Exon C8 from 14095-14187 as set out in SEQ ID NO: 3. A full length cDNA molecule for CA125 is set out in Table 4 and SEQ ID NO: 4. A CA125 protein is set out in Table 5 and SEQ ID NO: 5.


Now that the DNA sequence which encodes CA125 has been discovered known synthetic methods can be employed to prepare DNA molecules containing portions of the sequence. Conventional cloning vehicles, such as plasmids, viruses, or bacteria phages can be modified using known methods so as to produce novel cloning vehicles which contain cDNA encoding, CA125, analogs or mutants thereof. Similarly, such cloning vehicles can be modified or engineered so that they contain DNA molecules from Table 4 and SEQ ID NO: 4 or segments substantially similar thereto. The DNA molecule inserted may be made by various methods including enzymatic or chemical synthesis.


The CA125 gene has been cloned and multiple repeat sequences as well as the glycosylated amino terminal and the carboxy terminus have been identified. CA125 requires a transcript of more than 35,000 bases and occupies approximately 150,000 bp on chromosome 19p 13.2. The CA125 molecule comprises three major domains: an extracellular amino terminal domain (Domain 1); a large multiple repeat domain (Domain 2); and a carboxy terminal domain (Domain 3) which includes a transmembrane anchor with a short cytoplasmic domain. The amino terminal domain is assembled by combining five genomic exons, four very short amino terminal sequences and one extraordinarily large exon. This domain is dominated by its capacity for O-glycosylation and its resultant richness in serine and threonine residues. Additionally, an amino terminal extension is present, which comprises four genomic exons. Analysis of the amino terminal extension revealed that its amino acid composition is consistent with the amino acid composition of the amino terminal domain.


Perhaps even more significantly, the multiple repeat domains of CA125 or other domains could also be used for the development of a potential vaccine for patients with ovarian cancer. In order to induce cellular and humoral immunity in humans to CA125, murine antibodies specific for CA125 were utilized in anticipation of patient production of anti-ideotypic antibodies, thus indirectly allowing the induction of an immune response to the CA125 molecule. With the availability of recombinant CA125, especially domains which encompass epitope binding sites for known murine antibodies, it will be feasible to more directly stimulate patients' immune systems to CA125 and, as a result, extend the life of ovarian carcinoma patients.


The recombinant CA125 of the present invention may also be used to develop therapeutic targets. Molecules like CA125, which are expressed on the surface of tumor cells, provide potential targets for immune stimulation, drug delivery, biological modifier delivery or any agent which can be specifically delivered to ultimately kill the tumor cells. Humanized or human antibodies to CA125 epitopes could be used to deliver all drug or toxic agents including radioactive agents to mediate direct killing of tumor cells. Natural ligands having a natural binding affinity for domains on the CA125 molecule could also be utilized to deliver therapeutic agents to tumor cells.


CA125 expression may further provide a survival or metastatic advantage to ovarian tumor cells. Antisense oligonucleotides derived from the CA125 repeat sequences could be used to down-regulate the expression of CA125. Further, antisense therapy could be used in association with a tumor cell delivery system of the type described above.


Recombinant domains of the CA125 molecule also have the potential to identify small molecules, which bind to individual domains of the CA125 molecule. These small molecules could also be used as delivery agents or as biological modifiers.


In another aspect of the present invention, an isolated nucleic acid of the CA125 gene is disclosed, which comprises a nucleotide sequence selected from the group consisting of: (a) the nucleotide sequences set forth in SEQ ID NOS: 1, 2, 3 and 4; (b) a nucleotide sequence having at least 70% sequence identity to any one of the sequences in (a); (c) a degenerate variant of any one of (a) to (b); and (d) a fragment of any one of (a) to (c).


In another aspect of the present invention, an isolated nucleic acid of the CA125 gene, comprising a sequence that encodes a polypeptide with the amino acid sequence selected from the group consisting of: (a) the amino acid sequences set forth in SEQ ID NO: 5; (b) an amino acid sequence having at least 50% sequence identity to any one of the sequences in (a); (c) a conservative variant of any one of (a) to (b); and (d) a fragment of any one of (a) to (c).


The vector may be a cloning vector, a shuttle vector, or an expression vector. A cultured cell comprising the vector is also contemplated.


More specifically, this invention relates to a purified antibody that selectively binds to an epitope in the CA125 protein of SEQ ID NO: 5. Similarly, the purified antibody selectively binds to an amino acid sequence having at least 50% sequence identity to said sequence; the purified antibody selectively binds to an amino acid sequence having at least 60% sequence identity to said sequence; the purified antibody selectively binds to an amino acid sequence having at least 70% sequence identity to said sequence; the purified antibody selectively binds to an amino acid sequence having at least 80% sequence identity to said sequence; and the purified antibody selectively binds to an amino acid sequence having at least 90% sequence identity to said sequence. Additionally, purified antibody can be a conservative variant of the amino acid sequence set forth in SEQ ID NO: 5 or a fragment thereof.







DETAILED DESCRIPTION OF THE INVENTION

In accordance with the present invention, conventional molecular biology, microbiology, and recombinant DNA techniques may be used that will be apparent to those skilled in the relevant art. Such techniques are explained fully in the literature (see, e.g., Maniatis, Fritsch & Sambrook, “Molecular Cloning: A Laboratory Manual (1982); “DNA Cloning: A Practical Approach,” Volumes I and II (D. N. Glover ed. 1985); “Oligonucleotide Synthesis” (M. J. Gait ed. 1984); “Nucleic Acid Hybridization” (B. D. Hames & S. J. Higgins eds. (1985)); “Transcription and Translation” (B. D. flames & S. J. Higgins eds. (1984)); “Animal Cell Culture” (R. I. Freshney, ed. (1986)); “Immobilized Cells And Enzymes” (IRL Press, (1986)); and B. Perbal, “A Practical Guide To Molecular Cloning” (1984)).


Therefore, if appearing herein, the following terms shall have the definitions set out below.


A “vector” is a replicon, such as plasmid, phage or cosmid, to which another DNA segment may be attached so as to bring about the replication of the attached segment.


A “DNA molecule” refers to the polymeric form of deoxyribonucleotides (adenine, guanine, thymine, or cytosine) in either single stranded form, or a double-stranded helix. This term refers only to the primary and secondary structure of the molecule, and does not limit it to any particular tertiary forms. Thus, this term includes double-stranded DNA found, inter alia, in linear DNA molecules (e.g., restriction fragments), viruses, plasmids, and chromosomes.


As used herein, the term “gene” shall mean a region of DNA encoding a polypeptide chain.


“Messenger RNA” or “mRNA” shall mean an RNA molecule that encodes for one or more polypeptides.


“DNA polymerase” shall mean an enzyme which catalyzes the polymerization of deoxyribonucleotide triphosphates to make DNA chains using a DNA template.


“Reverse transcriptase” shall mean an enzyme which catalyzes the polymerization of deoxy- or ribonucleotide triphosphates to make DNA or RNA chains using an RNA or DNA template.


“Complementary DNA” or “cDNA” shall mean the DNA molecule synthesized by polymerization of deoxyribonucleotides by an enzyme with reverse transcriptase activity.


An “isolated nucleic acid” is a nucleic acid the structure of which is not identical to that of any naturally occurring nucleic acid or to that of any fragment of a naturally occurring genomic nucleic acid spanning more than three separate genes. The term therefore covers, for example, (a) a DNA which has the sequence of part of a naturally occurring genomic DNA molecule but is not flanked by both of the coding sequences that flank that part of the molecule in the genome of the organism in which it naturally occurs; (b) a nucleic acid incorporated into a vector or into the genomic DNA of a prokaryote or eukaryote in a manner such that the resulting molecule is not identical to any naturally occurring vector or genomic DNA; (c) a separate molecule such as a cDNA, a genomic fragment, a fragment produced by polymerase chain reaction (PCR), or a restriction fragment; and (d) a recombinant nucleotide sequence that is part of a hybrid gene, i.e., a gene encoding a fusion protein.


“Oligonucleotide”, as used herein in referring to the probes or primers of the present invention, is defined as a molecule comprised of two or more deoxy- or ribonucleotides, preferably more than ten. Its exact size will depend upon many factors which, in turn, depend upon the ultimate function and use of the oligonucleotide.


“DNA fragment” includes polynucleotides and/or oligonucleotides and refers to a plurality of joined nucleotide units formed from naturally-occurring bases and cyclofuranosyl groups joined by native phosphodiester bonds. This term effectively refers to naturally-occurring species or synthetic species formed from naturally-occurring subunits. “DNA fragment” also refers to purine and pyrimidine groups and moieties which function similarly but which have non naturally-occurring portions. Thus, DNA fragments may have altered sugar moieties or inter-sugar linkages. Exemplary among these are the phosphorothioate and other sulfur containing species. They may also contain altered base units or other modifications, provided that biological activity is retained. DNA fragments may also include species which include at least some modified base forms. Thus, purines and pyrimidines other than those normally found in nature may be so employed. Similarly, modifications on the cyclofuranose portions of the nucleotide subunits may also occur as long as biological function is not eliminated by such modifications.


“Primer” shall refer to an oligonucleotide, whether occurring naturally or produced synthetically, which is capable of acting as a point of initiation of synthesis when placed under conditions in which synthesis of a primer extension product, which is complementary to a nucleic acid strand, is induced, i.e., in the presence of nucleotides and an inducing agent such as a DNA polymerase and at a suitable temperature and pH. The primer may be either single-stranded or double-stranded and must be sufficiently long to prime the synthesis of the desired extension product in the presence of the inducing agent. The exact length of the primer will depend upon many factors, including temperature, the source of primer and the method used. For example, for diagnostic applications, depending on the complexity of the target sequence, the oligonucleotide primer typically contains 10-25 or more nucleotides, although it may contain fewer nucleotides.


The primers herein are selected to be “substantially” complementary to different strands of a particular target DNA sequence. This means that the primers must be sufficiently complementary to hybridize with their respective strands. Therefore, the primer sequence need not reflect the exact sequence of the template. For example, a non-complementary nucleotide fragment may be attached to the 5′ end of the primer, with the remainder of the primer sequence being complementary to the strand. Alternatively, non-complementary bases or longer sequences can be interspersed into the primer, provided that the primer sequence has sufficient complementarity with the sequence or hybridize therewith and thereby form the template for the synthesis of the extension product.


As used herein, the term “hybridization” refers generally to a technique wherein denatured RNA or DNA is combined with complementary nucleic acid sequence which is either free in solution or bound to a solid phase. As recognized by one skilled in the art, complete complementarity between the two nucleic acid sequences is not a pre-requisite for hybridization to occur. The technique is ubiquitous in molecular genetics and its use centers around the identification of particular DNA or RNA sequences within complex mixtures of nucleic acids.


As used herein, “restriction endonucleases” and “restriction enzymes” shall refer to bacterial enzymes which cut double-stranded DNA at or near a specific nucleotide sequence.


“Purified polypeptide” refers to any peptide generated from CA125 either by proteolytic cleavage or chemical cleavage.


“Degenerate variant” refers to any amino acid variation in the repeat sequence, which fulfills the homology exon structure and conserved sequences and is recognized by the M11, OC125 and ISOBM series of antibodies.


“Fragment” refers to any part of the CA125 molecule identified in a purification scheme.


“Conservative variant antibody” shall mean any antibody that fulfills the criteria of M11, OC125 or any of the ISOBM antibody series.


“Homology” refers to similarity based on identical base matches in alignment. When two sequences are identical there is a 100% homology, as base matches differ in alignment the homology between two sequences is reduced.


The CA125 gene has been cloned and multiple repeat sequences as well as the carboxy terminus have been identified. The cDNA for the CA125. gene is set out in SEQ ID NO: 4. The CA125 molecule comprises three major domains: an extracellular amino terminal domain (Domain I); a large multiple repeat domain (Domain 2); and a carboxy terminal domain (Domain 3) which includes a transmembrane anchor with a short cytoplasmic domain. The amino terminal domain is assembled by combining five genomic exons, four very short amino terminal sequences and one extraordinarily large exon. This domain is dominated by its capacity for O-glycosylation and its resultant richness in serine and threonine residues. Additionally, an amino terminal extension is present, which comprises four genomic exons. The amino acid composition of the amino terminal extension was found to be consistent with the amino acid composition of the amino terminal domain. The molecular structure is dominated by a repeat domain comprising 156 amino acid repeat units, which encompass the epitope binding sites. More than 60 repeat units have been identified, sequenced, and contiguously placed in the CA125 domain structure. The repeat units encompass an interactive disulfide bridged C-enclosure and the site of OC125 and M11 binding. The repeat sequences demonstrated 70-85% homology to each other. Expression of the repeats was demonstrated in E. coli. The CA125 molecule is anchored at its carboxy terminal through a transmembrane domain and a short cytoplasmic tail. The carboxy terminal also contains a proteolytic cleavage site approximately 50 amino acids upstream from the transmembrane domain, which allows for proteolytic cleavage and release of the CA125 molecule. Any one of the repeat domains has the potential for use as a new gold standard for detecting and monitoring the presence of the CA125 antigen. Further, the repeat domains or other domains, especially the c-terminal to the repeat domain also provide a basis for the development of a vaccine, which would be useful for the treatment of ovarian cancer and other carcinomas where CA125 is elevated.


The DNA sequences of the present invention can also be characterized as encoding the amino acid sequence equivalents of the amino acid sequence, equivalents, as used in this context, include peptides of substantially similar length and amino acid identity to those disclosed, but having conservative amino acid substitution at a non-critical residue position. A conservative amino acid substitution is a substitution in which an amino acid residue is replaced with an amino acid residue of differing identity, but whose R group can be characterized by chemically similar. Four common categories include: polor but uncharged R groups; positively charged R groups; negatively charged R groups; and, hydrophobic R groups. A preferred conservative substitution involves the substitution of a second hydrophobic residue for a fir hydrophobic residue, the first and second hydrophobic residues differing primarily in the size of the R group. The hydrophobic residue would be predicted to be located internally in the folded peptide structure and the mild pertubatim caused only by a change in the size of an R group at an internally located which would not alter the antigenicity of R protein. More specifically, two nucleic acid molecules are substantially equivalent if they have at least about 70% homology.


The isolated cDNA sequences (Table 4 and SEQ ID NO: 4) of the present invention can be inserted into an expression vector. Such vectors contain all necessary regulatory signals to promote the expression of a DNA sequence of interest. Expression vectors are typically either prokaryote or eukaryote specific. Expression vectors can be introduced into either prokaryote or eukaryote cells to produce CA125 proteins or portions thereof. The isolated cDNA sequence as shown in Table 4 was expressed to provide the CA125 molecule set out in Table 5 and SEQ ID NO: 5. The expressed CA125 is a polypeptide with the amino acid sequence set forth in SEQ ID NO: 5; an amino acid sequence having at least 50% sequence identity to the sequence, a conservative for variant or a fragment of any of the above. Two polypeptide sequences are substantially equivalent if there is at least 50% sequence homology and substantial similar physical characteristics. However, in practice, a portion of an isolated nucleic acid molecule set out in SEQ ID NO: 4 is expressed to obtain a fragment of the CA125 molecule. This fragment is then purified to obtain an isolated CA125 fragment.


In certain embodiments, “purified” refers to a polypeptide composition which has been subjected to fractionation to remove various nonprotein components such as other cellular components. Various techniques suitable for use in protein purification are known to those skilled in the relevant art. These techniques include, for example, precipitation with ammonium sulphate, PEG, antibodies and the like or by heat denaturation, followed by centrifugation; chromatography steps such as ion exchange, gel filtration, reverse phase, hydroxylapatite and affinity chromatography; isoelectric focusing; gel electrophoresis; and combination of such techniques. Similarly, a “purification scheme” is a technique or system to remove various nonprotein components such as other cellular components from the expressed protein. Various techniques suitable for use in protein purification are known to those skilled in the relevant art. These techniques include, for example, precipitation with ammonium sulphate, PEG, antibodies and the like or by heat denaturation, followed by centrifugation; chromatography steps such as ion exchange, gel filtration, reverse phase, hydroxylapatite and affinity chromatography; isoelectric focusing; gel electrophoresis; and combination of such techniques.


The genomic DNA and a full-length cDNA sequence of human CA125 has been determined. Additionally, a nucleic acid molecule encoding a 5′ upstream region of the CA125 gene has been determined. cDNA is expressed with the use of an expression vector. An expression vector is a carrying vector that has an inducer for expression built into the vector. Different vectors use different inducers. The cDNA is ligased into the expression vector using restriction digest sites designed in the vector. The cDNA must be ligased in the sense direction and in the correct reading frame for expression to occur. Once the cDNA is ligased into the expression vector, the construct is transformed into a cell. In the preferred embodiment, we use E. Coli bacteria, but the transformation can be done with yeast, mammalian cells, plants cells, etc. The transformed cells are then grown in culture and protein production is induced with the an inducing agent for the expression vector. In the preferred embodiment, we use the pQE-30 expression vector and induce with IPTG. Once induction has occurred, the cells are harvested and the protein is purified. It should be noted that some expression vectors add tags to the recombinant protein to aid in purification. For example, pQE-30 adds a His-Tag which binds to nickel to aid in purification. Once cells have been successfully transformed, a small aliquot can be frozen and stored for future use.


With a cDNA sequence, one skilled in the art has an easily renewable source of purified CA125. Portions of this cDNA sequence can be expressed to make CA125 polypeptides and these polypeptides can be used to make monoclonal antibodies. These monoclonal antibodies can be made by one skilled in the art to portions of the protein which heretofore do not have any monoclonal antibodies, such as the amino terminal sequence.


More specifically, the purified antibodies are made by the following process: the recombinant protein is injected into an animal (usually a mouse, but other animals can be used). The animal's B-lymphocytes produce antibodies to the protein. Each activated B lymphocyte forms a clone of cells in spleen or lymph nodes, with each cell of the clone producing identical antibody. These spleen cells are then harvested and fused with myeloma cells to produce hybridomas. These hybridomas are immortal and produce only one type of antibody. The hybridomas are selected from cells that did not fuse by selective media. The hybridomas can then be grown in large quantities to produce large quantities of monoclonal antibodies.


Therapeutic Targets: Molecules, which are expressed on the surface of tumor cells as CA125 is, offer potential targets for immune stimulation, drug delivery, biological modifier delivery or any agent which can be specifically delivered to ultimately kill the tumor cells. CA125 offers such potential as a target: 1) Antibodies to CA125 epitopes or newly described potential epitopes: Most especially humanized or human antibodies to CA125 which could directly activate the patients' immune system to attack and kill tumor cells. Antibodies could be used to deliver all drug or toxic agents, including radioactive agents to mediate direct killing of tumor cells. 2) Natural ligands: Under normal circumstances, molecules are bound to the CA125 molecule e.g. a 50 k dalton protein which does not contain CA125 epitopes co-purifies with CA125. Such a molecule, which might have a natural binding affinity for domains on the CA125 molecule, could also be utilized to deliver therapeutic agents to tumor cells.


Anti-sense therapy: CA125 expression may provide a survival or metastatic advantage to ovarian tumor cells as such antisense oligonucleotide derived from the CA125 sequence could be used to down-regulate the expression of CA125. Antisense therapy could be used in association with a tumor cell delivery system such as described above.


Small Molecules: Recombinant domains of CA125 also offer the potential to identify small molecules which bind to individual domains of the molecule. Small molecules either from combinatorial chemical libraries or small peptides can also be used as delivery agents or as biological modifiers.


Transgenic Animals/Transformed: CA125 and genomic DNA can be used to develop transgenic animal models and can be used under low stringency conditions, to clone CA125 cDNAs and genomic DNAs of other animal species. The CA125 cDNA can be used to prepare stable transformants. The bacterial cells could be transformed with CA125 cDNA to include these genes.


Example 1

Expression of 6×His-tagged CA125 repeat in E. coli: The open reading frame of the CA125 repeat was amplified by PCR with the 5′ sense primer 1 (5′-ACCGGATCCATGGGCCACACAGAGCCTGGCCC-3′) (SEQ ID NO: 6) and the 3′ antisense primer 2 (5′-TGTAAGCTTAGGCAGGGAGGATGGAGTCC-3′) (SEQ ID NO: 7). The open reading frame of the CA125 repeat constitutes a portion of the isolated nucleic acid molecule set out in SEQ ID NO: 4. PCR was performed in a reaction mixture consisting of ovarian tumor cDNA derived from 50 ng of mRNA, 5 pmol each of sense and antisense primers for the CA125 repeat, 0.2 mmol of dNTPs, and 0.625 U of Taq polymerase in 1× buffer in a final volume of 25 μl. This mixture was subjected to 1 minute of denaturation at 95° C. followed by 30 cycles of PCR consisting of the following: denaturation for 30 seconds at 95° C., 30 seconds of annealing at 62° C., and 1 minute of extension at 72° C. with an additional 7 minutes of extension on the last cycle. The product was electrophoresed through a 2% agarose gel for separation, the PCR product was purified and digested with the restriction enzymes BamHI and HindIII. This digested PCR product was ligated into the expression vector pQE-30, which had also been digested with BamHI and HindIII. The ligation reaction consisted of 1 ul of 10× ligation buffer, 1 ul of 10× bovine serum albumin (BSA), 1 ul of T4 ligase enzyme, and 7 ul of digested PCR product. The reaction went overnight at 15° C. This clone would allow for expression of recombinant amino-terminal 6×His-tagged CA125 repeat. The construct was then transformed into JM109 E. coli cells. The transformation reaction consisted of 5 ul of ligation reaction and 50 ul of cells. The reaction was mixed gently and then incubated on ice for 30 minutes. The reaction was then heat shocked at 42° C. for 45 seconds in a water bath before being returned to ice for 2 minutes. 500 ul of LB broth media were added and the mixture was incubated at 37° C. for 1 hour. At the end of 1 hour the cells were spun down in a microfuge at 4,000×g for 5 minutes and approximately 450 ul of media was removed. The cells were resuspended in the remaining 100 ul of media, transferred to a LAIX plate, and incubated overnight at 37° C. White colonies were picked from the plate and cultured in 5 ml LB broth media to determine if the transformation was successful. Transformed E. coli were grown in IL cultures to an OD600 of 1.5-2.0 at 37° C. and were induced with IPTG (0.1 mM) for 4-6 hours at 25° C. to produce recombinant protein. Whole E. coli lysate was electrophoresed through a denaturing 12% polyacrylamide gel and Coomassie stained to detect highly expressed proteins. His-tagged proteins were purified under denaturing conditions using Ni-NTA agarose metal chelating affinity chromatography available from Qiagen according to the manufacturer's instructions. Cells are spun down to remove liquid LB broth media. The cells are then resuspended in 40 ml of 8M Urea lysis buffer (pH 8.0) and incubated with agitation overnight at room temperature. The mixture is then spun down and the lysate is removed. The lysate is then incubated with Ni-NTA agarose beads with agitation overnight at room temperature. The beads are pelleted and the supernatant is removed. The beads are then washed twice in lysis buffer pH 8.0 plus Triton X, three times with lysis buffer pH 6.3 plus Triton X, and four times with lysis buffer pH 6.3 without Triton X. The protein is then eluted from the beads with lysis buffer pH4.2 plus 25 mM EDTA incubated overnight with agitation at room temperature. The beads are pelleted and the supernatant containing the recombinant protein is removed. The supernatant is then dialyzed twice in 0.2×PBS to remove the urea and freeze dried for storage. IL of culture produced 2.4 mg of recombinant protein.


It should be understood that various changes and modifications to the presently preferred embodiments described herein will be apparent to those skilled in the art. Such changes and modifications can be made without departing from the spirit and scope of the present invention and without diminishing its attendant advantages.









TABLE 1





Genomic CA125 Amino Terminal Sequence


(SEQ ID NO: 1)
















1
GGTGCGCACC ACTATGTCTG GCTAATTTTT GTATTTTTTT GTAGAGACAT





51
GGTTTCACCA TGTTGGCCAG GCTGGTCTCG AATTCCTGAC TTCAAGTAAT





101
CCACCCACCT CAGCCTCCCA AAGTGCTGGG ATTACAAGCA TGAGCCACCA





151
TGCATGGCCT AAAGCTTCTT TTAAAGCCAC CAAGTCCCTT CCCATGTTAG





201
CCCACTAATC CATGGGTTAG TCATGAATGG ATTAATCTAT TCATACGGAC





251
AGAGCCCTCA TCACCCAATC ACCTCTTAAA GGCCCCACCT CTCAATACTG





301
CCACACTGGG GATTAAGTTT CAACAGAGTT TTGGAGGGGA CATTCAAATC





351
ATAGTAATGC CCAAAGTGAA AAATCTTCCC TGCACTTTTC CCTCAACAAA





401
AACAGCCAGA GATAGTGAGC TGCCAGGAAA TTCTTTTTTT TTTCCTCTTC





451
TGTCCTAAAT CAGCATCGCT AGACCTTTAC ATGATTCAAC CTCATCTTCT





501
TCACCCTCTG GGTCATGAAA TTTTATTTAT TTATTTATTA TTTTCTTGGG





551
ACAGACTCTG GCTCTGTCGC CCAGGCTGAA GTGCAGTGGT GTGATCTTGG





601
CTCACTGCAA CCTCCGCCTC CCGGGTTCAA GCGATTCTCC TGCCTCAGCC





651
TCCTGAGTAG CTGGGATTAC AGGTGGGCGC CACCACACCC AGCTAATTTT





701
TTGTATTTTT AGTAGAGATG GGGTTTCACC ATATTAGCCA GGATGGTCTC





751
CATCTCTTGA CCTCGTGATC TGCCCACCTC AGCCTCCCAA AATGCTGGGA





801
TTACAGGCAT GAGACACCAC GCCCAGCAGG CCAGGGTCAT GAGATTTTAA





851
TCAAGAGCAA CTTCCACTGA TTCCTGAGAG TGCATCTGTG GGCCCCTGCT





901
CTGATCTGAA CAGAAGTGCC GTGTCTTCTC TGACCTCCAC TTCTCAATTC





951
AAGAGCCTTA GTATCTGCCA GTATCACACA CTGAGCATTA GCTCCATCTC





1001
ATGGGGGTGT AGGTAGGGGC TCTATCTGCA TCTTTCTTTC TTTTTTTCTT





1051
TCTTTCCCTT CCTCCCTTCC TCACTCCCTC GGTCCTCTCT TTCTTTCCTT





1101
TTCTTTCTTC CTTCCTCCCT TCCTCCCTCC CTCCCTCTCT CTTTCTCTCT





1151
TTCTTTCTTT CCTTCTTTCT TTCTTTCTCT CTTCCTTCCC TCCCTCCCTC





1201
CTTCCTTCCT TTCTCTTTCT TTCTCTTTCT TTCTTTTTTT CCTTCCTTCC





1251
TTCCTTCTTT CTCTTTCTCT CCCTCCCTTC CTTCCTTCCT TCCTTCCTTC





1301
CTTCCTTTCT TTCTTTCTTT CTTTCTTTCT TTCTTTCTTT CTTTCTTTCT





1351
TTCTTTCTTC CTTCCTTCCT TCCTTCCTTC CTTCCTTCCT TCCTTCCTTT





1401
CTTTTCTTTC TTTCTCTTTC TTTTTGAGAC AGAGCTCTTA TTACCCATGC





1451
TGGAGTGCAG TGGTGTGACC TTGGCTTACT GCAACATCTG CCTCCTAGGG





1501
TCAAGTGATT CTCCTGCCTC AGCCTCCTAA GTAGCTGGGA TTACAGACAC





1551
ATGCCACCAC ACCCAATATT TATTTTTATT AAAATTTTTT TTAAAATTAT





1601
TTTTAAAAAA TTAAAAATAA TTTTGTATTT TTAGTAGAGA CGGGGTTTCT





1651
CCATGTTGGT CAGGCTGATC TCAAACTCCC AACCTCAGGT GATCCTCCCA





1701
CCTCACCTCC CAAAGTGCTG GGATTACAGG CATGAGCCAC CGTGCCCAGC





1751
CTGGTTCCTG GTTTCTAAGA CATCACACAC ACACACACAC ACACACACAC





1801
ACACTCACAC ACTCAGAGAG AGAGAGAGAG AGAGGATCAT TAAGACATGA





1851
TACACTAAGA AATTCTATTC TGCAGACACT GAGAATCCGT TAAAAAGTTT





1901
GAAGGGAAGA ATTGAGATCA TCAGGTGTTT ATTTGAGGAA ATTGTCTGTG





1951
GTTGAACTAT CCTTTCCTTT CTCTCCCTGA GATTTGGTCT TCTCAATTAG





2001
AAGCGTTGCA CAATTCCCCC AACCTCCATA CATACGGCAG CTCTTCTAGA





2051
CACAGGTTTT CCCAGGTCAA ATGCGGGGAC CCCAGCCATA TCTCCCACCC





2101
TGAGAAATTT TGGAGTTTCA GGGAGCTCAG AAGCTCTGCA GAGGCCACCC





2151
TCTCTGAGGG GATTCTTCTT AGACCTCCAT CCAGAGGCAA ATGTTGACCT





Exon 1



2201
GTCCATGCTG AAACCCTCAG GCCTTCCTGG GTCATCTTCT CCCACCCGCT





2251

CCTTGATGAC AGGGAGCAGG AGCACTAAAG CCACACCAGA AATGGATTCA






2301

GGACTGACAG GAGCCACCTT GTCACCTAAG ACATCTACAG GTGCAATCGT






2351

GGTGACAGAA CATACTCTGC CCTTTACTTC CCCAGATAAG ACCTTGGCCA






2401

GTCCTACATC TTCGGTTGTG GGAAGAACCA CCCAGTCTTT GGGGGTGATG






2451

TCCTCTGCTC TCCCTGAGTC AACCTCTAGA GGAATGACAC ACTCCGAGCA






2501

AAGAACCAGC CCATCGCTGA GTCCCCAGGT CAATGGAACT CCCTCTAGGA






2551

ACTACCCTGC TACAAGCATG GTTTCAGGAT TGAGTTCCCC AAGGACCAGG






2601

ACCAGTTCCA CAGAAGGAAA TTTTACCAAA GAAGCATCTA CATACACACT






2651

CACTGTAGAG ACCACAAGTG GCCCAGTCAC TGAGAAGTAC ACAGTCCCCA






2701

CTGAGACCTC AACAACTGAA GGTGACAGCA CAGAGACCCC CTGGGACACA






2751

AGATATATTC CTGTAAAAAT CACATCTCCA ATGAAAACAT TTGCAGATTC






2801

AACTGCATCC AAGGAAAATG CCCCAGTGTC TATGACTCCA GCTGAGACCA






2851

CAGTTACTGA CTCACATACT CCAGGAAGGA CAAACCCATC ATTTGGGACA






2901

CTTTATTCTT CCTTCCTTGA CCTATCACCT AAAGGGACCC CAAATTCCAG






2951

AGGTGAAACA AGCCTGGAAC TGATTCTATC AACCACTGGA TATCCCTTCT






3001

CCTCTCCTGA ACCTGGCTCT GCAGGACACA GCAGAATAAG TACCAGTGCG






3051

CCTTTGTCAT CATCTGCTTC AGTTCTCGAT AATAAAATAT CAGAGACCAG






3101

CATATTCTCA GGCCAGAGTC TCACCTCCCC TCTGTCTCCT GGGGTGCCCG






3151

AGGCCAGAGC CAGCACAATG CCCAACTCAG CTATCCCTTT TTCCATGACA






3201

CTAAGCAATG CAGAAACAAG TGCCGAAAGG GTCAGAAGCA CAATTTCCTC






3251

TCTGGGGACT CCATCAATAT CCACAAAGCA GACAGCAGAG ACTATCCTTA






3301

CCTTCCATGC CTTCGCTGAG ACCATGGATA TACCCAGCAC CCACATAGCC






3351

AAGACTTTGG CTTCAGAATG GTTGGGAAGT CCAGGTACCC TTGGTGGCAC






3401

CAGCACTTCA GCGCTGACAA CCACATCTCC ATCTACCACT TTAGTCTCAG






3451

AGGAGACCAA CACCCATCAC TCCACGAGTG GAAAGGAAAC AGAAGGAACT






3501

TTGAATACAT CTATGACTCC ACTTGAGACC TCTGCTCCTG GAGAAGAGTC






3551

CGAAATGACT GCCACCTTGG TCCCCACTCT AGGTTTTACA ACTCTTGACA






3601

GCAAGATCAG AAGTCCATCT CAGGTCTCTT CATCCCACCC AACAAGAGAG






3651

CTCAGAACCA CAGGCAGCAC CTCTGGGAGG CAGAGTTCCA GCACAGCTGC






3701

CCACGGGAGC TCTGACATCC TGAGGGCAAC CACTTCCAGC ACCTCAAAAG






3751

CATCATCATG GACCAGTGAA AGCACAGCTC AGCAATTTAG TGAACCCCAG






3801

CACACACAGT GGGTGGAGAC AAGTCCTAGC ATGAAAACAG AGAGACCCCC






3851

AGCATCAACC AGTGTGGCAG CCCCTATCAC CACTTCTGTT CCCTCAGTGG






3901

TCTCTGGCTT CACCACCCTG AAGACCAGCT CCACAAAAGG GATTTGGCTT






3951

GAAGAAACAT CTGCAGACAC ACTCATCGGA GAATCCACAG CTGGCCCAAC






4001

CACCCATCAG TTTGCTGTTC CCACTGGGAT TTCAATGACA GGAGGCAGCA






4051

GCACCAGGGG AAGCCAGGGC ACAACCCACC TACTCACCAG AGCCACAGCA






4101

TCATCTGAGA CATCCGCAGA TTTGACTCTG GCCACGAACG GTGTCCCAGT






4151

CTCCGTGTCT CCAGCAGTGA GCAAGACGGC TGCTGGCTCA AGTCCTCCAG






4201

GAGGGACAAA GCCATCATAT ACAATGGTTT CTTCTGTCAT CCCTGAGACA






4251

TCATCTCTAC AGTCCTCAGC TTTCAGGGAA GGAACCAGCC TGGGACTGAC






4301

TCCATTAAAC ACTAGACATC CCTTCTCTTC CCCTGAACCA GACTCTGCAG






4351

GACACACCAA GATAAGCACC AGCATTCCTC TGTTGTCATC TGCTTCAGTT






4401

CTTGAGGATA AAGTGTCAGC GACCAGCACA TTCTCACACC ACAAAGCCAC






4451

CTCATCTATT ACCACAGGGA CTCCTGAAAT CTCAACAAAG ACAAAGCCCA






4501

GCTCAGCCGT TCTTTCCTCC ATGACCCTAA GCAATGCAGC AACAAGTCCT






4551

GAAAGAGTCA GAAATGCAAC TTCCCCTCTG ACTCATCCAT CTCCATCAGG






4601

GGAAGAGACA GCAGGGAGTG TCCTCACTCT CAGCACCTCT GCTGAGACTA






4651

CAGACTCACC TAACATCCAC CCAACTGGGA CACTGACTTC AGAATCGTCA






4701

GAGAGTCCTA GCACTCTCAG CCTCCCAAGT GTCTCTGGAG TCAAAACCAC






4751

ATTTTCTTCA TCTACTCCTT CCACTCATCT ATTTACTAGT GGAGAAGAAA






4801

CAGAGGAAAC TTCGAATCCA TCTGTGTCTC AACCTGAGAC TTCTGTTTCC






4851

AGAGTAAGGA CCACCTTGGC CAGCACCTCT GTCCCTACCC CAGTATTCCC






4901

CACCATGGAC ACCTGGCCTA CACGTTCAGC TCAGTTCTCT TCATCCCACC






4951

TAGTGAGTGA GCTCAGAGCT ACGAGCAGTA CCTCAGTTAC AAACTCAACT






5001

GGTTCAGCTC TTCCTAAAAT ATCTCACCTC ACTGGGACGG CAACAATGTC






5051

ACAGACCAAT AGAGACACGT TTAATGACTC TGCTGCACCC CAAAGCACAA






5101

CTTGGCCAGA GACTAGTCCC AGATTCAAGA CAGGGTTACC TTCAGCAACA






5151

ACCACTGTTT CAACCTCTGC CACTTCTCTC TCTGCTACTG TAATGGTCTC






5201

TAAATTCACT TCTCCAGCAA CTAGTTCCAT GGAAGCAACT TCTATCAGGG






5251

AACCATCAAC AACCATCCTC ACAACAGAGA CCACGAATGG CCCAGGCTCT






5301

ATGGCTGTGG CTTCTACCAA CATCCCAATT GGAAAGGGCT ACATTACTGA






5351

AGGAAGATTG GACACAAGCC ATCTGCCCAT TGGAACCACA GCTTCCTCTG






5401

AGACATCTAT GGATTTTACC ATGGCCAAAG AAAGTGTCTC AATGTCAGTA






5451

TCTCCATCTC AGTCCATGGA TGCTGCTGGC TCAAGCACTC CAGGAAGGAC






5501

AAGCCAATTC GTTGACACAT TTTCTGATGA TGTCTATCAT TTAACATCCA






5551

GAGAAATTAC AATACCTAGA GATGGAACAA GCTCAGCTCT GACTCCACAA






5601

ATGACTGCAA CTCACCCTCC ATCTCCTGAT CCTGGCTCTG CTAGAAGCAC






5651

CTGGCTTGGC ATCTTGTCCT CATCTCCTTC TTCTCCTACT CCCAAAGTCA






5701

CAATGAGCTC CACATTTTCA ACTCAGAGAG TCACCACAAG CATGATAATG






5751

GACACAGTTG AAACTAGTCG GTGGAACATG CCCAACTTAC CTTCCACGAC






5801

TTCCTTGACA CCAAGTAATA TTCCAACAAG TGGTGCCATA GGAAAAAGCA






5851

CCCTGGTTCC CTTGGACACT CCATCTCCAG CCACATCATT GGAGGCATCA






5901

GAAGGGGGAC TTCCAACCCT CAGCACCTAC CCTGAATCAA CAAACACACC






5951

CAGCATCCAC CTCGGAGCAC ACGCTAGTTC AGAAAGTCCA AGCACCATCA






6001

AACTTACCAT GGCTTCAGTA GTAAAACCTG GCTCTTACAC ACCTCTCACC






6051

TTCCCCTCAA TAGAGACCCA CATTCATGTA TCAACAGCCA GAATGGCTTA






6101

CTCTTCTGGG TCTTCACCTG AGATGACAGC TCCTGGAGAG ACTAACACTG






6151

GTAGTACCTG GGACCCCACC ACCTACATCA CCACTACGGA TCCTAAGGAT






6201

ACAAGTTCAG CTCAGGTCTC TACACCCCAC TCAGTGAGGA CACTCAGAAC






6251

CACAGAAAAC CATCCAAAGA CAGAGTCCGC CACCCCAGCT GCTTACTCTG






6301

GAAGTCCTAA AATCTCAAGT TCACCCAATC TCACCAGTCC GGCCACAAAA






6351

GCATGGACCA TCACAGACAC AACTGAACAC TCCACTCAAT TACATTACAC






6401

AAAATTGGCA GAAAAATCAT CTGGATTTGA GACACAGTCA GCTCCAGGAC






6451

CTGTCTCTGT AGTAATCCCT ACCTCCCCTA CCATTGGAAG CAGCACATTG






6501

GAACTAACTT CTGATGTCCC AGGGGAACCC CTGGTCCTTG CTCCCAGTGA






6551

GCAGACCACA ATCACTCTCC CCATGGCAAC ATGGCTGAGT ACCAGTTTGA






6601

CAGAGGAAAT GGCTTCAACA GACCTTGATA TTTCAAGTCC AAGTTCACCC






6651

ATGAGTACAT TTGCTATTTT TCCACCTATG TCCACACCTT CTCATGAACT






6701

TTCAAAGTCA GAGGCAGATA CCAGTGCCAT TAGAAATACA GATTCAACAA






6751

CGTTGGATCA GCACCTAGGA ATCAGGAGTT TGGGCAGAAC TGGGGACTTA






6801

ACAACTGTTC CTATCACCCC ACTGACAACC ACGTGGACCA GTGTGATTGA






6851

ACACTCAACA CAAGCACAGG ACACCCTTTC TGCAACGATG AGTCCTACTC






6901

ACGTGACACA GTCACTCAAA GATCAAACAT CTATACCAGC CTCAGCATCC






6951

CCTTCCCATC TTACTGAAGT CTACCCTGAG CTCGGGACAC AAGGGAGAAG






7001

CTCCTCTGAG GCAACCACTT TTTGGAAACC ATCTACAGAC ACACTGTCCA






7051

GAGAGATTGA GACTGGCCCA ACAAACATTC AATCCACTCC ACCCATGGAC






7101

AACACAACAA CAGGGAGCAG TAGTAGTGGA GTCACCCTGG GCATAGCCCA






7151

CCTTCCCATA GGAACATCCT CCCCAGCTGA GACATCCACA AACATGGCAC






7201

TGGAAAGAAG AAGTTCTACA GCCACTGTCT CTATGGCTGG GACAATGGGA






7251

CTCCTTGTTA CTAGTGCTCC AGGAAGAAGC ATCAGCCAGT CATTAGGAAG






7301

AGTTTCCTCT GTCCTTTCTG AGTCAACTAC TGAAGGAGTC ACAGATTCTA






7351

GTAAGGGAAG CAGCCCAAGG CTGAACACAC AGGGAAATAC AGCTCTCTCC






7401

TCCTCTCTTG AACCCAGCTA TGCTGAAGGA AGCCAGATGA GCACAAGCAT






7451

CCCTCTAACC TCATCTCCTA CAACTCCTGA TGTGGAATTC ATAGGGGGCA






7501

GCACATTTTG GACCAAGGAG GTCACCACAG TTATGACCTC AGACATCTCC






7551

AAGTCTTCAG CAAGGACAGA GTCCAGCTCA GCTACCCTTA TGTCCACAGC






7601

TTTGGGAAGC ACTGAAAATA CAGGAAAAGA AAAACTCAGA ACTGCCTCTA






7651

TGGATCTTCC ATCTCCAACT CCATCAATGG AGGTGACACC ATGGATTTCT






7701

CTCACTCTCA GTAATGCCCC CAATACCACA GATTCACTTG ACCTCAGCCA






7751

TGGGGTGCAC ACCAGCTCTG CAGGGACTTT GGCCACTGAC AGGTCATTGA






7801

ATACTGGTGT CACTAGAGCC TCCAGATTGG AAAACGGCTC TGATACCTCT






7851

TCTAAGTCCC TGTCTATGGG AAACAGCACT CACACTTCCA TGACTTACAC






7901

AGAGAAGAGT GAAGTGTCTT CTTCAATCCA TCCCCGACCT GAGACCTCAG






7951

CTCCTGGAGC AGAGACCACT TTGACTTCCA CTCCTGGAAA CAGGGCCATA






8001

AGCTTAACAT TGCCTTTTTC ATCCATTCCA GTGGAAGAAG TCATTTCTAC






8051

AGGCATAACC TCAGGACCAG ACATCAACTC AGCACCCATG ACACATTCTC






8101

CCATCACCCC ACCAACAATT GTATGGACCA GTACAGGCAC AATTGAACAG






8151

TCCACTCAAC CACTACATGC AGTTTCTTCA GAAAAAGTTT CTGTGCAGAC






8201

ACAGTCAACT CCATATGTCA ACTCTGTGGC AGTGTCTGCT TCCCCTACCC






8251

ATGAGAATTC AGTCTCTTCT GGAAGCAGCA CATCCTCTCC ATATTCCTCA






8301

GCCTCACTTG AATCCTTGGA TTCCACAATC AGTAGGAGGA ATGCAATCAC






8351

TTCCTGGCTA TGGGACCTCA CTACATCTCT CCCCACTACA ACTTGGCCAA






8401

GTACTAGTTT ATCTGAGGCA CTGTCCTCAG GCCATTCTGG GGTTTCAAAC






8451

CCAAGTTCAA CTACGACTGA ATTTCCACTC TTTTCAGCTG CATCCACATC






8501

TGCTGCTAAG CAAAGAAATC CAGAAACAGA GACCCATGGT CCCCAGAATA






8551

CAGCCGCGAG TACTTTGAAC ACTGATGCAT CCTCGGTCAC AGGTCTTTCT






8601

GAGACTCCTG TGGGGGCAAG TATCAGCTCT GAAGTCCCTC TTCCAATGGC






8651

CATAACTTCT AGATCAGATG TTTCTGGCCT TACATCTGAG AGTACTGCTA






8701

ACCCGAGTTT AGGCACAGCC TCTTCAGCAG GGACCAAATT AACTAGGACA






8751

ATATCCCTGC CCACTTCAGA GTCTTTGGTT TCCTTTAGAA TGAACAAGGA






8801

TCCATGGACA GTGTCAATCC CTTTGGGGTC CCATCCAACT ACTAATACAG






8851

AAACAAGCAT CCCAGTAAAC AGCGCAGGTC CACCTGGCTT GTCCACAGTA






8901

GCATCAGATG TAATTGACAC ACCTTCAGAT GGGGCTGAGA GTATTCCCAC






8951

TGTCTCCTTT TCCCCCTCCC CTGATACTGA AGTGACAACT ATCTCACATT






9001

TCCCAGAAAA GACAACTCAT TCATTTAGAA CCATTTCATC TCTCACTCAT






9051

GAGTTGACTT CAAGAGTGAC ACCTATTCCT GGGGATTGGA TGAGTTCAGC






9101

TATGTCTACA AAGCCCACAG GAGCCAGTCC CTCCATTACA CTGGGAGAGA






9151

GAAGGACAAT CACCTCTGCT GCTCCAACCA CTTCCCCCAT AGTTCTCACT






9201

GCTAGTTTCA CAGAGACCAG CACAGTTTCA CTGGATAATG AAACTACAGT






9251

AAAAACCTCA GATATCCTTG ACGCACGGAA AACAAATGAG CTCCCCTCAG






9301

ATAGCAGTTC TTCTTCTGAT CTGATCAACA CCTCCATAGC TTCTTCAACT






9351

ATGGATGTCA CTAAAACAGC CTCCATCAGT CCCACTAGCA TCTCAGGAAT






9401

GACAGCAAGT TCCTCCCCAT CTCTCTTCTC TTCAGATAGA CCCCAGGTTC






9451

CCACATCTAC AACAGAGACA AATACAGCCA CCTCTCCATC TGTTTCCAGT






9501

AACACCTATT CTCTTGATGG GGGCTCCAAT GTGGGTGGCA CTCCATCCAC






9551

TTTACCACCC TTTACAATCA CCCACCCTGT CGAGACAAGC TCGGCCCTAT






9601

TAGCCTGGTC TAGACCAGTA AGAACTTTCA GCACCATGGT CAGCACTGAC






9651

ACTGCCTCCG GAGAAAATCC TACCTCTAGC AATTCTGTGG TGACTTCTGT






9701

TCCAGCACCA GGTACATGGA CCAGTGTAGG CAGTACTACT GACTTACCTG






9751

CCATGGGCTT TCTCAAGACA AGTCCTGCAG GAGAGGCACA CTCACTTCTA






9801

GCATCAACTA TTGAACCAGC CACTGCCTTC ACTCCCCATC TCTCAGCAGC






9851

AGTGGTCACT GGATCCAGTG CTACATCAGA AGCCAGTCTT CTCACTACGA






9901

GTGAAAGCAA AGCCATTCAT TCTTCACCAC AGACCCCAAC TACACCCACC






9951

TCTGGAGCAA ACTGGGAAAC TTCAGCTACT CCTGAGAGCC TTTTGGTAGT






10001

CACTGAGACT TCAGACACAA CACTTACCTC AAAGATTTTG GTCACAGATA






10051

CCATCTTGTT TTCAACTGTG TCCACGCCAC CTTCTAAATT TCCAAGTACG






10101

GGGACTCTGT CTGGAGCTTC CTTCCCTACT TTACTCCCGG ACACTCCAGC






10151

CATCCCTCTC ACTGCCACTG AGCCAACAAG TTCATTAGCT ACATCCTTTG






10201

ATTCCACCCC ACTGGTGACT ATAGCTTCGG ATAGTCTTGG CACAGTCCCA






10251

GAGACTACCC TGACCATGTC AGAGACCTCA AATGGTGATG CACTGGTTCT






10301

TAAGACAGTA AGTAACCCAG ATAGGAGCAT CCCTGGAATC ACTATCCAAG






10351

GAGTAACAGA AAGTCCACTC CATCCTTCTT CCACTTCCCC CTCTAAGATT






10401

GTTGCTCCAC GGAATACAAC CTATGAAGGT TCGATCACAG TGGCACTTTC






10451

TACTTTGCCT GCGGGAACTA CTGGTTCCCT TGTATTCAGT CAGAGTTCTG






10501

AAAACTCAGA GACAACGGCT TTGGTAGACT CATCAGCTGG GCTTGAGAGG






10551

GCATCTGTGA TGCCACTAAC CACAGGAAGC CAGGGTATGG CTAGCTCTGG






10601

AGGAATCAGA AGTGGGTCCA CTCACTCAAC TGGAACCAAA ACATTTTCTT






10651

CTCTCCCTCT GACCATGAAC CCAGGTGAGG TTACAGCCAT GTCTGAAATC






10701

ACCACGAACA GACTGACAGC TACTCAATCA ACAGCACCCA AAGGGATACC






10751

TGTGAAGCCC ACCAGTGCTG AGTCAGGCCT CCTAACACCT GTCTCTGCCT






10801

CCTCAAGCCC ATCAAAGGCC TTTGCCTCAC TGACTACAGC TCCCCCAACT






10851

TGGGGGATCC CACAGTCTAC CTTGACATTT GAGTTTTCTG AGGTCCCAAG






10901

TTTGGATACT AAGTCCGCTT CTTTACCAAC TCCTGGACAG TCCCTGAACA






10951

CCATTCCAGA CTCAGATGCA AGCACAGCAT CTTCCTCACT GTCCAAGTCT






11001

CCAGAAAAAA ACCCAAGGGC AAGGATGATG ACTTCCACAA AGGCCATAAG






11051

TGCAAGCTCA TTTCAATCAA CAGGTTTTAC TGAAACCCCT GAGGGATCTG






11101

CCTCCCCTTC TATGGCAGGG CATGAACCCA GAGTCCCCAC TTCAGGAACA






11151

GGGGACCCTA GATATGCCTC AGAGAGCATG TCTTATCCAG ACCCAAGCAA






11201

GGCATCATCA GCTATGACAT CGACCTCTCT TGCATCAAAA CTCACAACTC






11251

TCTTCAGCAC AGGTCAAGCA GCAAGGTCTG GTTCTAGTTC CTCTCCCATA






11301

AGCCTATCCA CTGAGAAAGA AACAAGCTTC CTTTCCCCCA CTGCATCCAC






11351

CTCCAGAAAG ACTTCACTAT TTCTTGGGCC TTCCATGGCA AGGCAGCCCA






11401
ACATATTGGT GCATCTTCAG ACTTCAGCTC TGACACTTTC TCCAACATCC





11451

ACTCTAAATA TGTCCCAGGA GGAGCCTCCT GAGTTAACCT CAAGCCAGAC






11501

CATTGCAGAA GAAGAGGGAA CAACAGCTGA AACACAGACG TTAACCTTCA






11551

CACCATCTGA GACCCCAACA TCCTTGTTAC CTGTCTCTTC TCCCACAGAA






11601

CCCACAGCCA GAAGAAAGAG TTCTCCAGAA ACATGGGCAA GCTCTATTTC






11651

AGTTCCTGCC AAGACCTCCT TGGTTGAAAG TAAGAATGCC CTGCTCCTTC






11701
CCCAAGTGTG CTGGGGATGA ATCTGGAAAT AAACTACATC TTTTTTATTT





11751
TTTAAACTTT TATATTTGAA AATATAAATA TTTTAGGTTC AGGGAACATG





11801
TGCAGGTTTG TTATATAGGT AAATTGCATG TCATGGGGGC TTGGGGTACA





11851
GATTACATCA TCAGCCAGGT AATAAGCCTA GTACCTGATC AGTAGATTTT





11901
TTTTAATCCT CTCCCTCCTC CCAGCCTCCA CCCTCAATTC ACATGTCTCC





11951
ATGTGTACTC AAGGTTTAAT TCCCACTTAT GAGTGAGAAC ATGCGGTATT





12001
TGTAAACTAC ATCTTTATTT TTGCTAACCT CGAACTGAAA TTTAGCATTT





12051
GTTTTATTGA TGAATAGAGG TAACAAAACA AACCACATTA ATCCTAGCAG





12101
TGCCTGTGCC TTTGCCAACA ACAGAAATTC CGGACACTTT CATATCCTAT





12151
GACAATTGTT GCAAGCACTT TTAAAAATCA TGTACGACTT TATTCATAAT





12201
TATAGTGGTT ATTAGGCTTT TCAATAGATC TTATTTTATG AGTTAGTAAA





12251
ATAAGTGCCT GTATTATTGT ATTACATTTG TTTATTAAGA TCTTGATAAC





12301
AACATTTCAA TATAATCATT TCCTTTGTTT TTTAAATTTT AGATTCAGGG





12351
GTATATGTGC AGGTTTGTTA CGTGGATATA CTGCATAATG ATGAGGTTTG





12401
GCTTCTAGTG AACCCATCAG CCAAATAGTG AATGTTGTGC CCAATAAGTA





12451
GTTTTTCAAT CCTCACTTCA CTCCCAGCCT CCTCTATTTT GGAGTCCCAG





12501
TGTCTATTAT TTCTATCTTT ATGTCCACAT GTACCCATTG GTTAGCTCCC





12551
ACTTATAAGT GAGAATGTGC AGTATTTAAT TTTCTGTTTT TGAGTTATTT





12601
TGCTTAGGTT GATGGCCTTC AGCTCCAGCC ACGTTGCTTT AAAGAACATG





12651
ATTTCATTCT TTTTTATGGC TGCATAGTAC TCCGAGGTGT ATGTGTACCA





12701
GATTTTCTTT ATCCACAATG ATTTCCTTTG TAATCTAATA TTTTATATTG





12751
TTATTTTATG TTTTATTCTA TATTTTTATT TTAATTTATA AAGGAATTCA





12801
TATGGTTCAC AAGCCTGTCA AAGGGACCTA TAATAAAAAG AGGTTAAGAA





12851
TCCATGCTCT AAACAGAATA TTACTCCATT TTATTTCATT TATTTTTAAA





12901
GAGACAGTCT CACTCTGTCA TCCAGGCTGG AGTACAGTGG AGTGATCATA





12951
GCTCATTGCA ACCCTGAACT CTTGGGCACA AGCAATTCTC CTGCTTCATC





13001
CTCCAGAGGA GCTGGGACTA CAGGTGCACA TCACCATGCC CAGCTAGTTT





13051
TAAAAATTAT TTTGTAGAGA TGGTGTCTCA CTATCCTACC CAGGCTGGTC





13101
TCAAACTCCT GGGCTCAGGC AATCCTCCCA CTTTGACCTC CCAAAGTGTT





13151
GAGATTACAG GGGCAAGCCA CTGTGCCTGG CCACTTGTCA CATTTTAATT





13201
TGTGATTACT TATAAAATGA ACCCCTTCCC ATCTGAGATC TGTCAGTCTT





13251
TCTGGTGACG GTGCCTGGTG TCTGCTTTCT ACCATGTCCT GTTAGACTAG





13301
TGTTTGATGG GAGGTCACCT GGGCAGCTGT CCAGCTCACT CACTGGGCTC





13351
TAGAGCCTCT GAGTTGAAGC AAAATAGAAA GATCAGTCAA TGTAAAGAAA





13401
GCTCAAAAAC TGACATTCTG AAGTAATGGA TAGCTAAACC TTCCTATTGC





Exon 2



13451
CCTTTTCTTT CAGCAACTGA TGGAACGCTA GTGACCACCA TAAAGATGTC





13501

AAGCCAGGCA GCACAAGGAA ATTCCACGTG GCCTGCCCCA GCAGAGGAGA






13551

CGGGGACCAG TCCAGCAGGT AAATATAGAC CTTGTTTCCA TTTCTGCTCT






13601
GCTAATGCCA CCCAAGCCTT TCTTTTCTTT TCTTTTCTTT TCTTTTCTTT





13651
TCTTTTCTTT TCTTTTCTTT CTCTCCCTTT CTTTCTTTCT TTCTTTCTTT





13701
CTTTCTTTCT TTCTTTCTTT CTTTCTTTCT CTTTCTTTCT TTCTTTCTTT





13751
CTTTCTTTCT TTCTTTCTTT CTTTCTTTCT CTTTCTTTCT TCTTTCTCTC





13801
TCTCTCTTTC TTTCTTTCTC TTGTTCTTTT TAAATTTTTT ATTTTTTTAC





13851
TTAATTTTTT TCACCCAAGC CTTAAGGCCA GTTTGGACCA GATAGTGAGA





13901
CCCCACCTCT ATAAAAAAAA TTTTTAAAAA AAAAATAAGT TGGGCATCGT





13951
GCAGGCCTGT AGTCCCTGCT ACTCGAGAGG CCAAGGTGGG AGGACAGCTT





14001
GCTGCTGACT AAAAGTGCTG CTTATTGATT CTGGGAAGAA AAAATATACA





14051
AGGCTTCAGT TTCATTATTT TATAAGTAAA TGCTAGCAAC TTTTCCTTTC





14101
TTTCTCTCTT TCTCTCTTCC TCTCTTTCTC TCCTCTCCTT CTCTTCTCTC





14151
TCTCTCTCTC TCTCTCTCTC TTTCTCTCTC CTCTCCTTCT CTTCTCTTCT





14201
TTCTCTCTCT CTCTCTTTCA TTTATTTTTG AGACATGGTC TCATTCTGTC





14251
ACCCAGGCTG GAGTACAGTG GTGTATATTT ACTGCAGTAC TCACTGTACT





14301
CACTGCAGCC TCAAATTCCT GGGCTCAAGC TATCCTCTCA CCTCAGCCTC





14351
CTGAGTAGCT GGGCAGCAGT CCAGCTCACT CACTGGGCTC TAGAGCCTCT





14401
GTGCTATGCC CAGCTTATTG TTGTTGTTTT TTTAAATTTT TTTTTTTGTA





14451
CAGATGGGGT CTCACTATGT GGCCCAAGGT GGTCTTAAAC TCCTGGCTCC





14501
AAGAGATCCT CCCACCTCAG CCTCCCAAAG TGCAGGGATT ACAGGTGTGA





14551
GCCACTGTGC CCAGCCTAGA CAGCATTTTT TTTTTTTGAA ACAGGGTCTC





14601
CCTCTGTTGC CCAGGCTGGA GTGCAATGGC GTGTTCATGG TTCACTGCAG





14651
CCTCAGCCTC CTCAGTCTCA AGCAATCCTC CAACTTCAGC CTCCCCCAAC





14701
AGCTAGAACT GCAGGTGATC ATCACCAATT AGCCTGGTTA ATTGTGTGTG





14751
TATTTCTTAA ATTTTTTGTA GAGATAGTTC TCACTATATT GCTTGGGCTG





14801
GTCTCAAACT CCTGGACTCA AGTGATTCAC CTACCTCGGC CTCCCTAAGC





14851
ACTGGGATTA CAGGCTTGAG CCACCACACC CGGCAAGGAC TAGGTTTTAA





14901
AATAGGTTCC TAGGCTGGGT GTGGTGGCTT ACGCCCGTAA TCCCAGCACT





14951
TTGGGAGGCT GAGGTGGGCG GATCACGAGG TCAGGAGTTT GAGACCAGCC





15001
TGGCCAACAT AGTGAAACCC TGTCTCTACT AAAAATACAA AAAATTAGCT





15051
GGGCATAGTG GCACACACCT GTAATCCCAG CTACTCGGGA GGCTGAGGAA





15101
GGAGAATCAC TTGAACCTGG GAGGCGGAGG TTGCAGTGAG CCGAGATCAT





15151
GCCATTGCTC TCCAGCCTGG GTGACAGAGC AAGACTCCAT CTAAAAAAAA





15201
AAAAAAAAGT TCCTTTGACT TCTTGACACT CTTCTCTGAG GATATTGATC





15251
ATTTTTCCCC AATAGATGTT ACTAATTGAA CACTTCTGTT GCTTCAACTT





15301
ACTAATTTAC ATGATCAATA GCCAATTAAT TCAGCAGGAG AGAATGCTAC





15351
AGAGTCGATT CTTTCTGTAC TTTCTTCTGC TCCAGAGTGA AGGATCTTTC





15401
TAAATCAGAG ACCATCACTG TGTTCACAGG GAGGGCCTAG GTGAACCTGA





15451
GATGGCAAAT GTTGCGTTTG TTCTACGGAA GAAGGGATTA TGGGTTGAAG





15501
TCCTTGGCAG TGCCAAATTG CTTAGAAAAA TGTGAAATAT GGTCCCTAGG





15551
AGTGCTCTTG GGATGTCACA TTTTTCTCAC TCCTTTGACA GGTAGATGTT





15601
ATTTTCCTGA AGGCCAGGGA AAGGATTCAG AGGGAGGAAT GAATTTGAAA





15651
GAAAATGAAG GTGACGAGAA AGAATGAGCT CATCTCCCTT ATCCTCTTTC





15701
TTCTCAAATC CTTAAGTAGC TTTGCAGTGA ACTAAGATTT GGGGGAACCT





15751
AGAGGAGGCT GAAAGTTGGA AGCTGAAATT GGCTTAGCAA GGGCAAGCTC





15801
CAAAGACAAA AGTGGAAATA GTTTGGGGGT AGCCTTTTGC ATGGGTGAAA





15851
TCCTGGTTCA TCACATCCTC CCTTATGCAA AGAGCCCTTT TATATGGGGC





15901
ATGGGGAAAA ACTGAGCTAA AGGTGATAAT TTCTCCTGAG CAAGCCAGAT





15951
GGTCAAAGCT CTAACTTCAC CATCTCCCTT GGAATGTTTA ATGTGTTCCC





16001
TGGTGTCCAG AGGCTTAACG TGTGAGAATT AAAAGCTCAA CATTTTCTTT





16051
CCCAGGGAAG GAGGAAATAG TTTTAATTGA AATCCCGGGA GGAAATGAAT





16101
GATAGTGTCA AACCAAAAAA CTTCATCTTC TGTACCACTT GCATATACTC





Exon 3



16151
CACTGACTTA CTTTCTAATC ACAGGCACAT CCCCAGGAAG CCCAGAAATG





16201

TCTACCACTC TCAAAATCAT GAGCTCCAAG GAACCCGGCA TCAGCCCAGA






16251

GATCAGGTCC ACTGTGAGAA ATTCTCCTTG GAAGACTCCA GAAACAACTG






16301

TTCCCATGGA GACCACAGTG GAACCAGTCA CCCTTCAGTC CACAGCCCTA






16351

GGAAGTGGCA GCACCAGCAT CTCTCACCTG CCCACAGGAA CCACATCACC






16401

AACCAAGTCA CCAACAGAAA ATATGTTGGC TACAGAAAGG GTCTCCCTCT






16451

CCCCATCCCC ACCTGAGGCT TGGACCAACC TTTATTCTGG AACTCCAGGA






16501

GGGACCAGGC AGTCACTGGC CACAATGTCC TCTGTCTCCC TAGAGTCACC






16551

AACTGCTAGA AGCATCACAG GGACTGGTCA GCAAAGCAGT CCAGAACTGG






16601

TTTTAAAGAC AACTGGAATG GAATTCTCTA TGTGGCATGG CTCTACTGGA






16651

GGGACCACAG GGGACACACA TGTCTCTCTG AGCACATCTT CCAATATCCT






16701

TGAAGACCCT GTAACCAGCC CAAACTCTGT GAGCTCATTG ACAGATAAAT






16751

CCAAACATAA AACCGAGACA TGGGTCAGCA CCACAGCCAT TCCCTCCACT






16801

GTCCTGAATA ATAAGATAAT GGCAGCTGAA CAACAGACAA GTCGATCTGT






16851

GGATGAGGCT TATTCATCAA CTAGTTCTTG GTCAGATCAG ACATCTGGGA






16901

GTGACATCAC CCTTGGTGCA TCTCCTGATG TCACAAACAC ATTATACATC






16951

ACCTCCACAG CACAAACCAC CTCACTAGTA TCTCTGCCCT CTGGAGACCA






17001

AGGCATTACA AGCCTCACCA ATCCCTCAGG AGGAAAAACA AGCTCTGCAT






17051

CATCTGTCAC ATCTCCTTCA ATAGGGCTTG AGACTCTGAT GGCCAATGTA






17101

AGTGCAGTGA CAAGTGACAT TGCCCCTACT GCTGGGCATC TATCTCAGAC






17151

TTCATCTCCT GCGGAAGTGA GCATCCTGGA CATAACCACA GCTCCTACTC






17201

CAGGTATCTC CACCACCATC ACCACCATGG GAACCAACTC AATCTCAACT






17251

ACCACACCCA ACCCAGAAGT GGGTATGAGT ACCATGGACA GCACCCCGGC






17301

CACAGAGAGG CACACAACTT CTACAGAACA CCCTTCCACC TGGTCTTCCA






17351

CAGCTGCATC AGATTCCTGG ACTGTCACAG ACATGACTTC AAACTTGAAA






17401

GTTGCAAGAT CTCCTGGAAC AATTTCCACA ATGCATACAA CTTCATTCTT






17451

AGCCTCAAGC ACTGAATTAG ACTCCATGTC TACTCCCCAT GGCCGTATAA






17501

CTGTCATTGG AACCAGCCTG GTCACTCCAT CCTCTGATGC TTCAGCTGTA






17551

AAGACAGAGA CCAGTACAAG TGAAAGAACA TTGAGTCCTT CAGACACAAC






17601

TGCATCTACT CCCATCTCAA CTTTTTCTCG TGTCCAGAGG ATGAGCATCT






17651

CAGTTCCTGA CATTTTAAGT ACAAGTTGGA CTCCCAGTAG TACAGAAGCA






17701

GAAGATGTGC CTGTTTCAAT GGTTTCTACA GATCATGCTA GTACAAAGAC






17751

TGACCCAAAT ATGCCCCTGT CCACTTTTCT GTTTGATTCT CTGTCCACTC






17801

TTGACTGGGA CACTGGGAGA TCTCTGTCAT CAGCCACAGC CACTACCTCA






17851

GCTCCTCAGG GGGCCACAAC TCCCCAAGAA CTCACTTTGG AAACCATGAT






17901

CAGCCCAGCT ACCTCACAGT TGCCCTTCTC TATAGGGCAC ATTACAAGTG






17951

CAGTCATACC AGCTGCAATG GCAAGGAGCT CTGGAGTTAC TTTTTCAAGA






18001

CCAGATCCCA CAAGCAAAAA GGCAGAGCAG ACTTCCACTC AGCTTCCCAC






18051

CACCACTTCT GCACATCCAG AGCAGGTGCC CAGATCAGCA GCAACAACTC






18101

TGGATGTGAT CCCACACACA GCAAAAACTC CAGATGCAAC TTTTCAGAGA






18151

CAAGGGCAGA CAGCTCTTAC AACAGAGGCA AGAGCTACAT CTGACTCCTG






18201

GAATGAGAAA GAAAAATCAA CCCCAAGTGC ACCTTGGATC ACTGAGATGA






18251

TGAATTCTGT CTCAGAAGAT ACCATCAAGG AGGTTACCAG CTCCTCCAGT






18301

GTGTTAAGGA CCCTGAATAC GCTGGACATA AACTTGGAAT CTGGGACGAC






18351

TTCATCCCCA AGTTGGAAAA GCAGCCCATA TGAGAGAATT GCCCCTTCTG






18401

AGTCTACCAC AGACAAAGAG GCAATTCACC CTTCTACAAA CACAGTAGAG






18451

ACCACTGGCT GGGTCACAAG TTCCGAACAT GCTTCTCATT CCACTATCCC






18501

AGCCCACTCA GCGTCATCCA AACTCACATC TCCAGTGGTT ACAACCTCCA






18551

CCAGGGAACA AGCAATAGTT TCTATGTCAA CAACCACATG GCCAGAGTCT






18601

ACAAGGGCTA GAACAGAGCC TAATTCCTTC TTGACTATTG AACTGAGGGA






18651

CGTCAGCCCT TACATGGACA CCAGCTCAAC CACACAAACA AGTTTTATCT






18701

CTTCCCCAGG TTCCACTGCG ATCACCAAGG GGCCTAGAAC AGAAATTACC






18751

TCCTCTAAGA GAATATCCAG CTCATTCCTT GCCCAGTCTA TGAGGTCGTC






18801

AGACAGCCCC TCAGAAGCCA TCTCCAGGCT GTCTAACTTT CCTGCCATGA






18851

CAGAATCTGG AGGAATGATC CTTGCTATGC AAACAAGTCC ACCTGGCGCT






18901

ACATCACTAA GTGCACCTAC TTTGGATACA TCAGCCACAG CCTCCTGGAC






18951

AGGGACTCCA CTGGCTACGA CTCAGAGATT TACATACTCA GAGAAGACCA






19001

CTCTCTTTAG CAAAGGTCCT GAGGATACAT CACAGCCAAG CCCTCCCTCT






19051

GTGGAAGAAA CCAGCTCTTC CTCTTCCCTG GTACCTATCA ATGCTACAAC






19101

CTCGCCTTCC AATATTTTGT TGACATCACA AGGGCACAGT CCCTCCTCTA






19151

CTCCACCTGT GACCTCAGTT TTCTTGTCTG AGACCTCTGG CCTGGGGAAG






19201

ACCACAGACA TGTCGAGGAT AAGCTTGGAA CCTGGCACAA GTTTACCTCC






19251

CAATTTGAGC AGTACAGCAG GTGAGGCGTT ATCCACTTAT GAAGCCTCCA






19301

GAGATACAAA GGCAATTCAT CATTCTGCAG ACACAGCAGT GACGAATATG






19351

GAGGCAACCA GTTCTGAATA TTCTCCTATC CCAGGCCATA CAAAGCCATC






19401

CAAAGCCACA TCTCCATTGG TTACCTCCCA CATCATGGGG GACATCACTT






19451

CTTCCACATC AGTATTTGGC TCCTCCGAGA CCACAGAGAT TGAGACAGTG






19501

TCCTCTGTGA ACCAGGGACT TCAGGAGAGA AGCACATCCC AGGTGGCCAG






19551

CTCTGCTACA GAGACAAGCA CTGTCATTAC CCATGTGTCT AGTGGTGATG






19601

CTACTACTCA TGTCACCAAG ACACAAGCCA CTTTCTCTAG CGGAACATCC






19651

ATCTCAAGCC CTCATCAGTT TATAACTTCT ACCAACACAT TTACAGATGT






19701

GAGCACCAAC CCCTCCACCT CTCTGATAAT GACAGAATCT TCAGGAGTGA






19751

CCATCACCAC CCAAACAGGT CCTACTGGAG CTGCAACACA GGGTCCATAT






19801

CTCTTGGACA CATCAACCAT GCCTTACTTG ACAGAGACTC CATTAGCTGT






19851

GACTCCAGAT TTTATGCAAT CAGAGAAGAC CACTCTCATA AGCAAAGGTC






19901

CCAAGGATGT GTCCTGGACA AGCCCTCCCT CTGTGGCAGA AACCAGCTAT






19951

CCCTCTTCCC TGACACCTTT CTTGGTCACA ACCATACCTC CTGCCACTTC






20001

CACGTTACAA GGGCAACATA CATCCTCTCC TGTTTCTGCG ACTTCAGTTC






20051

TTACCTCTGG ACTGGTGAAG ACCACAGATA TGTTGAACAC AAGCATGGAA






20101

CCTGTGACCA ATTCACCTCA AAATTTGAAC AATCCATCAA ATGAGATACT






20151

GGCCACTTTG GCAGCCACCA CAGATATAGA GACTATTCAT CCTTCCATAA






20201

ACAAAGCAGT GACCAATATG GGGACTGCCA GTTCAGCACA TGTACTGCAT






20251

TCCACTCTCC CAGTCAGCTC AGAACCATCT ACAGCCACAT CTCCAATGGT






20301

TCCTGCCTCC AGCATGGGGG ACGCTCTTGC TTCTATATCA ATACCTGGTT






20351

CTGAGACCAC AGACATTGAG GGAGAGCCAA CATCCTCCCT GACTGCTGGA






20401

CGAAAAGAGA ACAGCACCCT CCAGGAGATG AACTCAACTA CAGAGTCAAA






20451

CATCATCCTC TCCAATGTGT CTGTGGGGGC TATTACTGAA GCCACAAAAA






20501

TGGAAGTCCC CTCTTTTGAT GCAACATTCA TACCAACTCC TGCTCAGTCA






20551

ACAAAGTTCC CAGATATTTT CTCAGTAGCC AGCAGTAGAC TTTCAAACTC






20601

TCCTCCCATG ACAATATCTA CCCACATGAC CACCACCCAG ACAGGGTCTT






20651

CTGGAGCTAC ATCAAAGATT CCACTTGCCT TAGACACATC AACCTTGGAA






20701

ACCTCAGCAG GGACTCCATC AGTGGTGACT GAGGGGTTTG CCCACTCAAA






20751

AATAACCACT GCAATGAACA ATGATGTCAA GGACGTGTCA CAGACAAACC






20801

CTCCCTTTCA GGATGAAGCC AGCTCTCCCT CTTCTCAAGC ACCTGTCCTT






20851

GTCACAACCT TACCTTCTTC TGTTGCTTTC ACACCGCAAT GGCACAGTAC






20901

CTCCTCTCCT GTTTCTATGT CCTCAGTTCT TACTTCTTCA CTGGTAAAGA






20951

CCGCAGGCAA GGTGGATACA AGCTTAGAAA CAGTGACCAG TTCACCTCAA






21051

AGATATAGAG ACAACGCATC CTTCCATAAA CACAGTAGTT ACCAATGTGG






21101

GGACCACCGG TTCAGCATTT GAATCACATT CTACTGTCTC AGCTTACCCA






21151

GAGCCATCTA AAGTCACATC TCCAAATGTT ACCACCTCCA CCATGGAAGA






21201

CACCACAATT TCCAGATCAA TACCTAAATC CTCTAAGACT ACAAGAACTG






21251

AGACTGAGAC AACTTCCTCC CTGACTCCTA AACTGAGGGA GACCAGCGTC






21301

TCCCAGGAGA TCACCTCGTC CACAGAGACA AGCACTGTTC CTTACAAAGA






21351

GCTCACTGGT GCCACTACCG AGGTATCCAG GACAGATGTC ACTTCCTCTA






21401

GCAGTACATC CTTCCCTGGC CCTGATCAGT CCACAGTGTC ACTAGACATC






21451

TCCACAGAAA CCAACACCAG GCTGTCTACC TCCCCAATAA TGACAGAATC






21501

TGCAGAAATA ACCATCACCA CCCAAACAGG TCCTCATGGG GCTACATCAC






21551

AGGATACTTT TACCATGGAC CCATCAAATA CAACCCCCCA GGCAGGGATC






21601

CACTCAGCTA TGACTCATGG ATTTTCACAA TTGGATGTGA CCACTCTTAT






21651

GAGCAGAATT CCACAGGATG TATCATGGAC AAGTCCTCCC TCTGTGGATA






21701

AAACCAGCTC CCCCTCTTCC TTTCTGCCCT CACCTGCAAT GACCACACCT






21751

TCCCTGATTT CTTCTACCTT ACCAGAGGAT AAGCTCTCCT CTCCTATGAC






21801

TTCACTTCTC ACCTCTGGCC TAGTGAAGAT TACAGACATA TTACGTACAC






21851

GCTTGGAACC TGTGACCAGC TCACTTCCAA ATTTCAGCAG CACCTCAGAT






21901

AAGATACTGG CCACTTCTAA AGACAGTAAA GACACAAAGG AAATTTTTCC






21951

TTCTATAAAC ACAGAAGAGA CCAATGTGAA AGCCAACAAC TCTGGACATG






22001

AATCCCATTC CCCTGCACTG GCTGACTCAG AGACACCCAA AGCCACAACT






22051

CAAATGGTTA TCACCACCAC TGTGGGAGAT CCAGCTCCTT CCACATCAAT






22101

GCCAGTGCAT GGTTCCTCTG AGACTACAAA CATTAAGAGA GAGCCAACAT






22151

ATTTCTTGAC TCCTAGACTG AGAGAGACCA GTACCTCTCA GGAGTCCAGC






22201

TTTCCCACGG ACACAAGTTT TCTACTTTCC AAAGTCCCCA CTGGTACTAT






22251

TACTGAGGTC TCCAGTACAG GGGTCATCTC TTCTAGCAAA ATTTCCACCC






22301

CAGACCATGA TAAGTCCACA GTGCCACCTG ACACCTTCAC AGGAGAGATC






22351

CCCAGGGTCT TCACCTCCTC TATTAAGACA AAATCTGCAG AAATGACGAT






22401

CACCACCCAA GCAAGTCCTC CTGAGTCTGC ATCGCACAGT ACCCTTCCCT






22451

TGGACACATC AACCACACTT TCCCAGGGAG GGACTCATTC AACTGTGACT






22501

CAGGGATTCC CATACTCAGA GGTGACCACT CTCATGGGCA TGGGTCCTGG






22551

GAATGTGTCA TGGATGACAA CTCCCCCTGT GGAAGAAACC AGCTCTGTGT






22601

CTTCCCTGAT GTCTTCACCT GCCATGACAT CCCCTTCTCC TGTTTCCTCC






22651

ACATCACCAC AGAGCATCCC CTCCTCTCCT CTTCCTGTGA CTGCACTTCC






22701

TACTTCTGTT CTGGTGACAA CCACAGATGT GTTGGGCACA ACAAGCCCAG






22751

AGTCTGTAAC CAGTTCACCT CCAAATTTGA GCAGCATCAC TCATGAGAGA






22801

CCGGCCACTT ACAAAGACAC TGCACACACA GAAGCCGCCA TGCATCATTC






22851

CACAAACACC GCAGTGACCA ATGTAGGGAC TTCCGGGTCT GGACATAAAT






22901

CACAATCCTC TGTCCTAGCT GACTCAGAGA CATCGAAAGC CACACCTCTG






22951

ATGAGTACCA CCTCCACCCT GGGGGACACA AGTGTTTCCA CATCAACTCC






23001

TAATATCTCT CAGACTAACC AAATTCAAAC AGAGCCAACA GCATCCCTGA






23051

GCCCTAGACT GAGGGAGAGC AGCACGTCTG AGAAGACCAG CTCAACAACA






23101

GAGACAAATA CTGCCTTTTC TTATGTGCCC ACAGGTGCTA TTACTCAGGC






23151

CTCCAGAACA GAAATCTCCT CTAGCAGAAC ATCCATCTCA GACCTTGATC






23201

GGTCCACAAT AGCACCCGAC ATCTCCACAG GAATGATCAC CAGGCTCTTC






23251

ACCTCCCCCA TCATGACAAA ATCTGCAGAA ATGACCGTCA CCACTCAAAC






23301

AACTACTCCT GGGGCTACAT CACAGGGTAT CCTTCCCTGG GACACATCAA






23351

CCACACTTTT CCAGGGAGGG ACTCATTCAA CCGTGTCTCA GGGATTCCCA






23401

CACTCAGAGA TAACCACTCT TCGGAGCAGA ACCCCTGGAG ATGTGTCATG






23451

GATGACAACT CCCCCTGTGG AAGAAACCAG CTCTGGGTTT TCCCTGATGT






23501

CACCTTCCAT GACATCCCCT TCTCCTGTTT CCTCCACATC ACCAGAGAGC






23551

ATCCCCTCCT CTCCTCTCCC TGTGACTGCA CTTCTTACTT CTGTTCTGGT






23601

GACAACCACA AATGTATTGG GCACAACAAG CCCAGAGCCC GTAACGAGTT






23651

CACCTCCAAA TTTAAGCAGC CCCACACAGG AGAGACTGAC CACTTACAAA






23701

GACACTGCGC ACACAGAAGC CATGCATGCT TCCATGCATA CAAACACTGC






23751

AGTGGCCAAC GTGGGGACCT CCATTTCTGG ACATGAATCA CAATCTTCTG






23801

TCCCAGCTGA TTCAGACACA TCCAAAGCCA CATCTCCAAT GGGTACCACC






23851

TTCGCCATGG GGGATACAAG TGTTTCTACA TCAACTCCTG CCTTCTTTGA






23901

GACTAGAATT CAGACTGAAT CAACATCCTC TTTGATTCCT GGATTAAGGG






23951

ACACCAGGAC GTCTGAGGAG ATCAACACTG TGACAGAGAC CAGCACTGTC






24001

CTTTCAGAAG TGCCCACTAC TACTACTACT GAGGTCTCCA GGACAGAAGT






24051

TATCACTTCC AGCAGAACAA CCATCTCAGG GCCTGATCAT TCCAAAATGT






24101

CACCCTACAT CTCCACAGAA ACCATCACCA GGCTCTCCAC TTTTCCTTTT






24151

GTAACAGGAT CCACAGAAAT GGCCATCACC AACCAAACAG GTCCTATAGG






24201

GACTATCTCA CAGGCTACCC TTACCCTGGA CACATCAAGC ACAGCTTCCT






24251

GGGAAGGGAC TCACTCACCT GTGACTCAGA GATTTCCACA CTCAGAGGAG






24301

ACCACTACTA TGAGCAGAAG TACTAAGGGC GTGTCATGGC AAAGCCCTCC






24351

CTCTGTGGAA GAAACCAGTT CTCCTTCTTC CCCAGTGCCT TTACCTGCAA






24401

TAACCTCACA TTCATCTCTT TATTCCGCAG TATCAGGAAG TAGCCCCACT






24451

TCTGCTCTCC CTGTGACTTC CCTTCTCACC TCTGGCAGGA GGAAGACCAT






24501

AGACATGTTG GACACACACT CAGAACTTGT GACCAGCTCC TTACCAAGTG






24551

CAAGTAGCTT CTCAGGTGAG ATACTCACTT CTGAAGCCTC CACAAATACA






24601

GAGACAATTC ACTTTTCAGA GAACACAGCA GAAACCAATA TGGGGACCAC






24651

CAATTCTATG CATAAACTAC ATTCCTCTGT CTCAATCCAC TCCCAGCCAT






24701

CCGGACACAC ACCTCCAAAG GTTACTGGAT CTATGATGGA GGACGCTATT






24751

GTTTCCACAT CAACACCTGG TTCTCCTGAG ACTAAAAATG TTGACAGAGA






24801

CTCAACATCC CCTCTGACTC CTGAACTGAA AGAGGACAGC ACCGCCCTGG






24851

TGATGAACTC AACTACAGAG TCAAACACTG TTTTCTCCAG TGTGTCCCTG






24901

GATGCTGCTA CTGAGGTCTC CAGGGCAGAA GTCACCTACT ATGATCCTAC






24951

ATTCATGCCA GCTTCTGCTC AGTCAACAAA GTCCCCAGAC ATTTCACCTG






25001

AAGCCAGCAG CAGTCATTCT AACTCTCCTC CCTTGACAAT ATCTACACAC






25051

AAGACCATCG CCACACAAAC AGGTCCTTCT GGGGTGACAT CTCTTGGCCA






25101

ACTGACCCTG GACACATCAA CCATAGCCAC CTCAGCAGGA ACTCCATCAG






25151

CCAGAACTCA GGATTTTGTA GATTCAGAAA CAACCAGTGT CATGAACAAT






25201

GATCTCAATG ATGTGTTGAA GACAAGCCCT TTCTCTGCAG AAGAAGCCAA






25251

CTCTCTCTCT TCTCAGGCAC CTCTCCTTGT GACAACCTCA CCTTCTCCTG






25301

TAACTTCCAC ATTGCAAGAG CACAGTACCT CCTCTCTTGT TTCTGTGACC






25351

TCAGTACCCA CCCCTACACT GGCGAAGATC ACAGACATGG ACACAAACTT






25401

AGAACCTGTG ACTCGTTCAC CTCAAAATTT AAGGAACACC TTGGCCACTT






25451

CAGAAGCCAC CACAGATACA CACACAATGC ATCCTTCTAT AAACACAGCA






25501

GTGGCCAATG TGGGGACCAC CAGTTCACCA AATGAATTCT ATTTTACTGT






25551

CTCACCTGAC TCAGACCCAT ATAAAGCCAC ATCCGCAGTA GTTATCACTT






25601

CCACCTCGGG GGACTCAATA GTTTCCACAT CAATGCCTAG ATCCTCTGCG






25651

ATGAAAAAGA TTGAGTCTGA GACAACTTTC TCCCTGATAT TTAGACTGAG






25701

GGAGACTAGC ACCTCCCAGA AAATTGGCTC ATCCTCAGAC ACAAGCACGG






25751

TCTTTGACAA AGCATTCACT GCTGCTACTA CTGAGGTCTC CAGAACAGAA






25801

CTCACCTCCT CTAGCAGAAC ATCCATCCAA GGCACTGAAA AGCCCACAAT






25851

GTCACCGGAC ACCTCCACAA GATCTGTCAC CATGCTTTCT ACTTTTGCTG






25901

GCCTGACAAA ATCCGAAGAA AGGACCATTG CCACCCAAAC AGGTCCTCAT






25951

AGGGCGACAT CACAGGGTAC CCTTACCTGG GACACATCAA TCACAACCTC






26001

ACAGGCAGGG ACCCACTCAG CTATGACTCA TGGATTTTCA CAATTAGATT






26051

TGTCCACTCT TACGAGTAGA GTTCCTGAGT ACATATCAGG GACAAGCCCA






26101

CCCTCTGTGG AAAAAACCAG CTCTTCCTCT TCCCTTCTGT CTTTACCAGC






26151

AATAACCTCA CCGTCCCCTG TACCTACTAC ATTACCAGAA AGTAGGCCGT






26201

CTTCTCCTGT TCATCTGACT TCACTCCCCA CCTCTGGCCT AGTGAAGACC






26251

ACAGATATGC TGGCATCTGT GGCCAGTTTA CCTCCAAACT TGGGCAGCAC






26301

CTCACATAAG ATACCGACTA CTTCAGAAGA CATTAAAGAT ACAGAGAAAA






26351

TGTATCCTTC CACAAACATA GCAGTAACCA ATGTGGGGAC CACCACTTCT






26401

GAAAAGGAAT CTTATTCGTC TGTCCCAGCC TACTCAGAAC CACCCAAAGT






26451

CACCTCTCCA ATGGTTACCT CTTTCAACAT AAGGGACACC ATTGTTTCCA






26501

CATCCATGCC TGGCTCCTCT GAGATTACAA GGATTGAGAT GGAGTCAACA






26551

TTCTCCCTGG CTCATGGGCT GAAGGGAACC AGCACCTCCC AGGACCCCAT






26601

CGTATCCACA GAGAAAAGTG CTGTCCTTCA CAAGTTGACC ACTGGTGCTA






26651

CTGAGACCTC TAGGACAGAA GTTGCCTCTT CTAGAAGAAC ATCCATTCCA






26701

GGCCCTGATC ATTCCACAGA GTCACCAGAC ATCTCCACTG AAGTGATCCC






26751

CAGCCTGCCT ATCTCCCTTG GCATTACAGA ATCTTCAAAT ATGACCATCA






26801

TCACTCGAAC AGGTCCTCCT CTTGGCTCTA CATCACAGGG CACATTTACC






26851

TTGGACACAC CAACTACATC CTCCAGGGCA GGAACACACT CGATGGCGAC






26901

TCAGGAATTT CCACACTCAG AAATGACCAC TGTCATGAAC AAGGACCCTG






26951

AGATTCTATC ATGGACAATC CCTCCTTCTA TAGAGAAAAC CAGCTTCTCC






27001

TCTTCCCTGA TGCCTTCACC AGCCATGACT TCACCTCCTG TTTCCTCAAC






27051

ATTACCAAAG ACCATTCACA CCACTCCTTC TCCTATGACC TCACTGCTCA






27101

CCCCTAGCCT AGTGATGACC ACAGACACAT TGGGCACAAG CCCAGAACCT






27151

ACAACCAGTT CACCTCCAAA TTTGAGCAGT ACCTCACATG AGATACTGAC






27201

AACAGATGAA GACACCACAG CTATAGAAGC CATGCATCCT TCCACAAGCA






27251

CAGCAGCGAC TAATGTGGAA ACCACCAGTT CTGGACATGG GTCACAATCC






27301

TCTGTCCTAG CTGACTCAGA AAAAACCAAG GCCACAGCTC CAATGGATAC






27351

CACCTCCACC ATGGGGCATA CAACTGTTTC CACATCAATG TCTGTTTCCT






27401

CTGAGACTAC AAAAATTAAG AGAGAGTCAA CATATTCCTT GACTCCTGGA






27451

CTGAGAGAGA CCAGCATTTC CCAAAATGCC AGCTTTTCCA CTGACACAAG






27501

TATTGTTCTT TCAGAAGTCC CCACTGGTAC TACTGCTGAG GTCTCCAGGA






27551

CAGAAGTCAC CTCCTCTGGT AGAACATCCA TCCCTGGCCC TTCTCAGTCC






27601

ACAGTTTTGC CAGAAATATC CACAAGAACA ATGACAAGGC TCTTTGCCTC






27651

GCCCACCATG ACAGAATCAG CAGAAATGAC CATCCCCACT CAAACAGGTC






27701

CTTCTGGGTC TACCTCACAG GATACCCTTA CCTTGGACAC ATCCACCACA






27751

AAGTCCCAGG CAAAGACTCA TTCAACTTTG ACTCAGAGAT TTCCACACTC






27801

AGAGATGACC ACTCTCATGA GCAGAGGTCC TGGAGATATG TCATGGCAAA






27851

GCTCTCCCTC TCTGGAAAAT CCCAGCTCTC TCCCTTCCCT GCTGTCTTTA






27901

CCTGCCACAA CCTCACCTCC TCCCATTTCC TCCACATTAC CAGTGACTAT






27951

CTCCTCCTCT CCTCTTCCTG TGACTTCACT TCTCACCTCT AGCCCGGTAA






28001

CGACCACAGA CATGTTACAC ACAAGCCCAG AACTTGTAAC CAGTTCACCT






28051

CCAAAGCTGA GCCACACTTC AGATGAGAGA CTGACCACTG GCAAGGACAC






28101

CACAAATACA GAAGCTGTGC ATCCTTCCAC AAACACAGCA GCGTCCAATG






28151

TGGAGATTCC CAGCTCTGGA CATGAATCCC CTTCCTCTGC CTTAGCTGAC






28201

TCAGAGACAT CCAAAGCCAC ATCACCAATG TTTATTACCT CCACCCAGGA






28251

GGATACAACT GTTGCCATAT CAACCCCTCA CTTCTTGGAG ACTAGCAGAA






28301

TTCAGAAAGA GTCAATTTCC TCCCTGAGCC CTAAATTGAG GGAGACAGGC






28351

AGTTCTGTGG AGACAAGCTC AGCCATAGAG ACAAGTGCTG TCCTTTCTGA






28401

AGTGTCCGTT GGTGCTACTA CTGAGATCTC CAGGACAGAA GTCACCTCCT






28451

CTAGCAGAAC ATCCATCTCT GGTTCTGCTG AGTCCACAAT GTTGCCAGAA






28501

ATATCCACCA CAAGAAAAAT CATTAAGTTC CCTACTTCCC CCATCCTGGC






28551

AGAATCATCA GAAATGACCA TCAAGACCCA AACAAGTCCT CCTGGGTCTA






28601

CATCAGAGAG TACCTTTACA TTAGACACAT CAACCACTCC CTCCTTGGTA






28651

ATAACCCATT CGACTATGAC TCAGAGATTG CCACACTCAG AGATAACCAC






28701

TCTTGTGAGT AGAGGTGCTG GGGATGTGCC ACGGCCCAGC TCTCTCCCTG






28751

TGGAAGAAAC AAGCCCTCCA TCTTCCCAGC TGTCTTTATC TGCCATGATC






28801

TCACCTTCTC CTGTTTCTTC CACATTACCA GCAAGTAGCC ACTCCTCTTC






28851

TGCTTCTGTG ACTTCACTTC TCACACCAGG CCAAGTGAAG ACTACTGAGG






28901

TGTTGGACGC AAGTGCAGAA CCTGAAACCA GTTCACCTCC AAGTTTGAGC






28951

AGCACCTCAG TTGAAATACT GGCCACCTCT GAAGTCACCA CAGATACGGA






29001

GAAAATTCAT CCTTTCTCAA ACACGGCAGT AACCAAAGTT GGAACTTCCA






29051

GTTCTGGACA TGAATCCCCT TCCTCTGTCC TACCTGACTC AGAGACAACC






29101

AAAGCCACAT CGGCAATGGG TACCATCTCC ATTATGGGGG ATACAAGTGT






29151

TTCTACATTA ACTCCTGCCT TATCTAACAC TAGGAAAATT CAGTCAGAGC






29201

CAGCTTCCTC ACTGACCACC AGATTGAGGG AGACCAGCAC CTCTGAAGAG






29251

ACCAGCTTAG CCACAGAAGC AAACACTGTT CTTTCTAAAG TGTCCACTGG






29301

TGCTACTACT GAGGTCTCCA GGACAGAAGC CATCTCCTTT AGCAGAACAT






29351

CCATGTCAGG CCCTGAGCAG TCCACAATGT CACAAGACAT CTCCATAGGA






29401

ACCATCCCCA GGATTTCTGC CTCCTCTGTC CTGACAGAAT CTGCAAAAAT






29451

GACCATCACA ACCCAAACAG GTCCTTCGGA GTCTACACTA GAAAGTACCC






29501

TTAATTTGAA CACAGCAACC ACACCCTCTT GGGTGGAAAC CCACTCTATA






29551

GTAATTCAGG GATTTCCACA CCCAGAGATG ACCACTTCCA TGGGCAGAGG






29601

TCCTGGAGGT GTGTCATGGC CTAGCCCTCC CTTTGTGAAA GAAACCAGCC






29651

CTCCATCCTC CCCGCTGTCT TTACCTGCCG TGACCTCACC TCATCCTGTT






29701

TCCACCACAT TCCTAGCACA TATCCCCCCC TCTCCCCTTC CTGTGACTTC






29751

ACTTCTCACC TCTGGCCCGG CGACAACCAC AGATATCTTG GGTACAAGCA






29801

CAGAACCTGG AACCAGTTCA TCTTCAAGTT TGAGCACCAC CTCCCATGAG






29851

AGACTGACCA CTTACAAAGA CACTGCACAT ACAGAAGCCG TGCATCCTTC






29901

CACAAACACA GGAGGGACCA ATGTGGCAAC CACCAGCTCT GGATATAAAT






29951

CACAGTCCTC TGTCCTAGCT GACTCATCTC CAATGTGTAC CACCTCCACC






30001

ATGGGGGATA CAAGTGTTCT CACATCAACT CCTGCCTTCC TTGAGACTAG






30051

GAGGATTCAG ACAGAGCTAG CTTCCTCCCT GACCCCTGGA TTGAGGGAGT






30101

CCAGTGGCTC TGAAGGGACC AGCTCAGGCA CCAAGATGAG CACTGTCCTC






30151

TCTAAAGTGC CCACTGGTGC TACTACTGAG ATCTCCAAGG AAGACGTCAC






30201

CTCCATCCCA GGTCCCGCTC AATCCACAAT ATCACCAGAC ATCTCCACAA






30251

GAACCGTCAG CTGGTTCTCT ACATCCCCTG TCATGACAGA ATCAGCAGAA






30301

ATAACCATGA ACACCCATAC AAGTCCTTTA GGGGCCACAA CACAAGGCAC






30351

CAGTACTTTG GCCACGTCAA GCACAACCTC TTTGACAATG ACACACTCAA






30401

CTATATCTCA AGGATTTTCA CACTCACAGA TGAGCACTCT TATGAGGAGG






30451

GGTCCTGAGG ATGTATCATG GATGAGCCCT CCCCTTCTGG AAAAAACTAG






30501

ACCTTCCTTT TCTCTGATGT CTTCACCAGC CACAACTTCA CCTTCTCCTG






30551

TTTCCTCCAC ATTACCAGAG AGCATCTCTT CCTCTCCTCT TCCTGTGACT






30601

TCACTCCTCA CGTCTGGCTT GGCAAAAACT ACAGATATGT TGCACAAAAG






30651

CTCAGAACCT GTAACCAACT CACCTGCAAA TTTGAGCAGC ACCTCAGTTG






30701

AAATACTGGC CACCTCTGAA GTCACCACAG ATACAGAGAA AACTCATCCT






30751

TCTTCAAACA GAACAGTGAC CGATGTGGGG ACCTCCAGTT CTGGACATGA






30801

ATCCACTTCC TTTGTCCTAG CTGACTCACA GACATCCAAA GTCACATCTC






30851

CAATGGTTAT TACCTCCACC ATGGAGGATA CGAGTGTCTC CACATCAACT






30901

CCTGGCTTTT TTGAGACTAG CAGAATTCAG ACAGAACCAA CATCCTCCCT






30951

GACCCTTGGA CTGAGAAAGA CCAGCAGCTC TGAGGGGACC AGCTTAGCCA






31001

CAGAGATGAG CACTGTCCTT TCTGGAGTGC CCACTGGTGC CACTGCTGAA






31051

GTCTCCAGGA CAGAAGTCAC CTCCTCTAGC AGAACATCCA TCTCAGGCTT






31101

TGCTCAGCTC ACAGTGTCAC CAGAGACTTC CACAGAAACC ATCACCAGAC






31151

TCCCTACCTC CAGCATAATG ACAGAATCAG CAGAAATGAT GATCAAGACA






31201

CAAACAGATC CTCCTGGGTC TACACCAGAG AGTACTCATA CTGTGGACAT






31251

ATCAACAACA CCCAACTGGG TAGAAACCCA CTCGACTGTG ACTCAGAGAT






31301

TTTCACACTC AGAGATGACC ACTCTTGTGA GCAGAAGCCC TGGTGATATG






31351

TTATGGCCTA GTCAATCCTC TGTGGAAGAA ACCAGCTCTG CCTCTTCCCT






31401

GCTGTCTCTG CCTGCCACGA CCTCACCTTC TCCTGTTTCC TCTACATTAG






31451

TAGAGGATTT CCCTTCCGCT TCTCTTCCTG TGACTTCTCT TCTCACCCCT






31501

GGCCTGGTGA TAACCACAGA CAGGATGGGC ATAAGCAGAG AACCTGGAAC






31551

CAGTTCCACT TCAAATTTGA GCAGCACCTC CCATGAGAGA CTGACCACTT






31601

TGGAAGACAC TGTAGATACA GAAGACATGC AGCCTTCCAC ACACACAGCA






31651

GTGACCAACG TGAGGACCTC CATTTCTGGA CATGAATCAC AATCTTCTGT






31701

CCTATCTGAC TCAGAGACAC CCAAAGCCAC ATCTCCAATG GGTACCACCT






31751

ACACCATGGG GGAAACGAGT GTTTCCATAT CCACTTCTGA CTTCTTTGAG






31801

ACCAGCAGAA TTCAGATAGA ACCAACATCC TCCCTGACTT CTGGATTGAG






31851

GGAGACCAGC AGCTCTGAGA GGATCAGCTC AGCCACAGAG GGAAGCACTG






31901

TCCTTTCTGA AGTGCCCAGT GGTGCTACCA CTGAGGTCTC CAGGACAGAA






31951

GTGATATCCT CTAGGGGAAC ATCCATGTCA GGGCCTGATC AGTTCACCAT






32001

ATCACCAGAC ATCTCTACTG AAGCGATCAC CAGGCTTTCT ACTTCCCCCA






32051

TTATGACAGA ATCAGCAGAA AGTGCCATCA CTATTGAGAC AGGTTCTCCT






32101

GGGGCTACAT CAGAGGGTAC CCTCACCTTG GACACCTCAA CAACAACCTT






32151

TTGGTCAGGG ACCCACTCAA CTGCATCTCC AGGATTTTCA CACTCAGAGA






32201

TGACCACTCT TATGAGTAGA ACTCCTGGAG ATGTGCCATG GCCGAGCCTT






32251

CCCTCTGTGG AAGAAGCCAG CTCTGTCTCT TCCTCACTGT CTTCACCTGC






32301

CATGACCTCA ACTTCTTTTT TCTCCACATT ACCAGAGAGC ATCTCCTCCT






32351

CTCCTCATCC TGTGACTGCA CTTCTCACCC TTGGCCCAGT GAAGACCACA






32401

GACATGTTGC GCACAAGCTC AGAACCTGAA ACCAGTTCAC CTCCAAATTT






32451

GAGCAGCACC TCAGCTGAAA TATTAGCCAC GTCTGAAGTC ACCAAAGATA






32501

GAGAGAAAAT TCATCCCTCC TCAAACACAC CTGTAGTCAA TGTAGGGACT






32551

GTGATTTATA AACATCTATC CCCTTCCTCT GTTTTGGCTG ACTTAGTGAC






32601

AACAAAACCC ACATCTCCAA TGGCTACCAC CTCCACTCTG GGGAATACAA






32651

GTGTTTCCAC ATCAACTCCT GCCTTCCCAG AAACTATGAT GACACAGCCA






32701

ACTTCCTCCC TGACTTCTGG ATTAAGGGAG ATCAGTACCT CTCAAGAGAC






32751

CAGCTCAGCA ACAGAGAGAA GTGCTTCTCT TTCTGGAATG CCCACTGGTG






32801

CTACTACTAA GGTCTCCAGA ACAGAAGCCC TCTCCTTAGG CAGAACATCC






32851

ACCCCAGGTC CTGCTCAATC CACAATATCA CCAGAAATCT CCACGGAAAC






32901

CATCACTAGA ATTTCTACTC CCCTCACCAC GACAGGATCA GCAGAAATGA






32951

CCATCACCCC CAAAACAGGT CATTCTGGGG CATCCTCACA AGGTACCTTT






33001

ACCTTGGACA CATCAAGCAG AGCCTCCTGG CCAGGAACTC ACTCAGCTGC






33051

AACTCACAGA TCTCCACACT CAGGGATGAC CACTCCTATG AGCAGAGGTC






33101

CTGAGGATGT GTCATGGCCA AGCCGCCCAT CAGTGGAAAA AACTAGCCCT






33151

CCATCTTCCC TGGTGTCTTT ATCTGCAGTA ACCTCACCTT CGCCACTTTA






33201

TTCCACACCA TCTGAGAGTA GCCACTCATC TCCTCTCCGG GTGACTTCTC






33251

TTTTCACCCC TGTCATGATG AAGACCACAG ACATGTTGGA CACAAGCTTG






33301

GAACCTGTGA CCACTTCACC TCCCAGTATG AATATCACCT CAGATGAGAG






33351

TCTGGCCACT TCTAAAGCCA CCATGGAGAC AGAGGCAATT CAGCTTTCAG






33401

AAAACACAGC TGTGACTCAG ATGGGCACCA TCAGCGCTAG ACAAGAATTC






33451

TATTCCTCTT ATCCAGGCCT CCCAGAGCCA TCCAAAGTGA CATCTCCAGT






33501

GGTCACCTCT TCCACCATAA AAGACATTGT TTCTACAACC ATACCTGCTT






33551

CCTCTGAGAT AACAAGAATT GAGATGGAGT CAACATCCAC CCTGACCCCC






33601

ACACCAAGGG AGACCAGCAC CTCCCAGGAG ATCCACTCAG CCACAAAGCC






33651

AAGCACTGTT CCTTACAAGG CACTCACTAG TGCCACGATT GAGGACTCCA






33701

TGACACAAGT CATGTCCTCT AGCAGAGGAC CTAGCCCTGA TCAGTCCACA






33751

ATGTCACAAG ACATATCCAG TGAAGTGATC ACCAGGCTCT CTACCTCCCC






33801

CATCAAGGCA GAATCTACAG AAATGACCAT TACCACCCAA ACAGGTTCTC






33851

CTGGGGCTAC ATCAAGGGGT ACCCTTACCT TGGACACTTC AACAACTTTT






33901

ATGTCAGGGA CCCACTCAAC TGCATCTCAA GGATTTTCAC ACTCACAGAT






33951

GACCGCTCTT ATGAGTAGAA CTCCTGGAGA TGTGCCATGG CTAAGCCATC






34001

CCTCTGTGGA AGAAGCCAGC TCTGCCTCTT TCTCACTGTC TTCACCTGTC






34051

ATGACCTCAT CTTCTCCCGT TTCTTCCACA TTACCAGACA GCATCCACTC






34101

TTCTTCGCTT CCTGTGACAT CACTTCTCAC CTCAGGGCTG GTGAAGACCA






34151

CAGAGCTGTT GGGCACAAGC TCAGAACCTG AAACCAGTTC ACCCCCAAAT






34201

TTGAGCAGCA CCTCAGCTGA AATACTGGCC ACCACTGAAG TCACTACAGA






34251

TACAGAGAAA CTGGAGATGA CCAATGTGGT AACCTCAGGT TATACACATG






34301

AATCTCCTTC CTCTGTCCTA GCTGACTCAG TGACAACAAA GGCCACATCT






34351

TCAATGGGTA TCACCTACCC CACAGGAGAT ACAAATGTTC TCACATCAAC






34401

CCCTGCCTTC TCTGACACCN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN






34451
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





34501
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNCGGAAA CCAAGTTTCT





Exon 4



34551
AACCAACCCC TCCTTTTTGA CCCCAGTAGG ATTCAAACAA AGTCAAAGCT





34601

CTCACTGACT CCTGGGTTGA TGGAGACCAG CATCTCTGAA GAGACCAGCT






34651

CTGCCACAGA AAAAAGCACT GTCCTTTCTA GTGTGCCCAC TGGTGCTACT






34701

ACTGAGGTCT CCAGGACAGA AGCCATCTCT TCTAGCAGAA CATCCATCCC






34751

AGGCCCTGCT CAATCCACAA TGTCATCAGA CACCTCCATG GAAACCATCA






34801

CTAGAATTTC TACCCCCCTC ACAAGGAAAG AATCAACAGA CATGGCCATC






34851

ACCCCCAAAA CAGGTCCTTC TGGGGCTACC TCGCAGGGTA CCTTTACCTT






34901

GGACTCATCA AGCACAGCCT CCTGGCCAGG AACTCACTCA GCTACAACTC






34951

AGAGATTTCC ACAGTCAGTG GTGACAACTC CTATGAGCAG AGGTCCTGAG






35001

GATGTGTCAT GGCCAAGCCC GCTGTCTGTG GAAAAAAACA GCCCTCCATC






35051

TTCCCTGGTA TCTTCATCTT CAGTAACCTC ACCTTCGCCA CTTTATTCCA






35101

CACCATCTGG GAGTAGCCAC TCCTCTCCTG TCCCTGTCAC TTCTCTTTTC






35151

ACCTCTATCA TGATGAAGGC CACAGACATG TTGGATGCAA GTTTGGAACC






35201

TGAGACCACT TCAGCTCCCA ATATGAATAT CACCTCAGAT GAGAGTCTGG






35251

CCACTTCTAA AGCCACCACG GAGACAGAGG CAATTCACGT TTTTGAAAAT






35301

ACAGCAGCGT CCCATGTGGA AACCACCAGT GCTACAGAGG AACTCTATTC






35351

CTCTTCCCCA GGCTTCTCAG AGCCAACAAA AGTGATATCT CCAGTGGTCA






35401

CCTCTTCCTC TATAAGAGAC AACATGGTTT CCACAACAAT GCCTGGCTCC






35451

TCTGGCATTA CAAGGATTGA GATAGAGTCA ATGTCATCTC TGACCCCTGG






35501

ACTGAGGGAG ACCAGAACCT CCCAGGACAT CACCTCATCC ACAGAGACAA






35551

GCACTGTCCT TTACAAGATG TCCTCTGGTG CCACTCCTGA GGTCTCCAGG






35601

ACAGAAGTTA TGCCCTCTAG CAGAACATCC ATTCCTGGCC CTGCTCAGTC






35651

CACAATGTCA CTAGACATCT CCGATGAAGT TGTCACCAGG CTGTCTACCT






35701

CTCCCATCAT GACAGAATCT GCAGAAATAA CCATCACCAC CCAAACAGGT






35751

TATTCTCTGG CTACATCCCA GGTTACCCTT CCCTTGGGCA CCTCAATGAC






35801

CTTTTTGTCA GGGACCCACT CAACTATGTC TCAAGGACTT TCACACTCAG






35851

AGATGACCAA TCTTATGAGC AGGGGTCCTG AAAGTCTGTC ATGGACGAGC






35901

CCTCGCTTTG TGGAAACAAC TAGATCTTCC TCTTCTCTGA CATCATTACC






35951

TCTCACGACC TCACTTTCTC CTGTGTCCTC CACATTACTA GACAGTAGCC






36001

CCTCCTCTCC TCTTCCTGTG ACTTCACTTA TCCTCCCAGG CCTGGTGAAG






36051

ACTACAGAAG TGTTGGATAC AAGCTCAGAG CCTAAAACCA GTTCATCTCC






36101

AAATTTGAGC AGCACCTCAG TTGAAATACC GGCCACCTCT GAAATCATGA






36151

CAGATACAGA GAAAATTCAT CCTTCCTCAA ACACAGCGGT GGCCAAAGTG






36201

AGGACCTCCA GTTCTGTTCA TGAATCTCAT TCCTCTGTCC TAGCTGACTC






36251

AGAAACAACC ATAACCATAC CTTCAATGGG TATCACCTCC GCTGTGGACG






36301

ATACCACTGT TTTCACATCA AATCCTGCCT TCTCTGAGAC TAGGAGGATT






36351

CCGACAGAGC CAACATTCTC ATTGACTCCT GGATTCAGGG AGACTAGCAC






36401

CTCTGAAGAG ACCACCTCAA TCACAGAAAC AAGTGCAGTC CTTTATGGAG






36451

TGCCCACTAG TGCTACTACT GAAGTCTCCA TGACAGAAAT CATGTCCTCT






36501

AATAGAACAC ACATCCCTGA CTCTGATCAG TCCACGATGT CTCCAGACAT






36551

CATCACTGAA GTGATCACCA GGCTCTCTTC CTCATCCATG ATGTCAGAAT






36601

CAACACAAAT GACCATCACC ACCCAAAAAA GTTCTCCTGG GGCTACAGCA






36651

CAGAGTACTC TTACCTTGGC CACAACAACA GCCCCCTTGG CAAGGACCCA






36701

CTCAACTGTT CCTCCTAGAT TTTTACACTC AGAGATGACA ACTCTTATGA






36751

GTAGGAGTCC TGAAAATCCA TCATGGAAGA GCTCTCCCTT TGTGGAAAAA






36801

ACTAGCTCTT CATCTTCTCT GTTGTCCTTA CCTGTCACGA CCTCACCTTC






36851

TGTTTCTTCC ACATTACCGC AGAGTATCCC TTCCTCCTCT TTTTCTGTGA






36901

CTTCACTCCT CACCCCAGGC ATGGTGAAGA CTACAGACAC AAGCACAGAA






36951

CCTGGAACCA GTTTATCTCC AAATCTGAGT GGCACCTCAG TTGAAATACT






37001

GGCTGCCTCT GAAGTCACCA CAGATACAGA GAAAATTCAT CCTTCTTCAA






37051

GCATGGCAGT GACCAATGTG GGAACCACCA GTTCTGGACA TGAACTATAT






37101

TCCTCTGTTT CAATCCACTC GGAGCCATCC AAGGCTACAT ACCCAGTGGG






37151

TACTCCCTCT TCCATGGCTG AAACCTCTAT TTCCACATCA ATGCCTGCTA






37201

ATTTTGAGAC CACAGGATTT GAGGCTGAGC CATTTTCTCA TTTGACTTCT






37251

GGATTTAGGA AGACAAACAT GTCCCTGGAC ACCAGCTCAG TCACACCAAC






37301

AAATACACCT TCTTCTCCTG GGTCCACTCA CCTTTTACAG AGTTCCAAGA






37351

CTGATTTCAC CTCTTCTGCA AAAACATCAT CCCCAGACTG GCCTCCAGCC






37401

TCACAGTATA CTGAAATTCC AGTGGACATA ATCACCCCCT TTAATGCTTC






37451

TCCATCTATT ACGGAGTCCA CTGGGATAAC CTCCTTCCCA GAATCCAGGT






37501

TTACTATGTC TGTAACAGAA AGTACTCATC ATCTGAGTAC AGATTTGCTG






37551

CCTTCAGCTG AGACTATTTC CACTGGCACA GTGATGCCTT CTCTATCAGA






37601

GGCCATGACT TCATTTGCCA CCACTGGAGT TCCACGAGCC ATCTCAGGTT






37651

CAGGTAGTCC ATTCTCTAGG ACAGAGTCAG GCCCTGGGGA TGCTACTCTG






37701

TCCACCATTG CAGAGAGCCT GCCTTCATCC ACTCCTGTGC CATTCTCCTC






37751

TTCAACCTTC ACTACCACTG ATTCTTCAAC CATCCCAGCC CTCCATGAGA






37801

TAACTTCCTC TTCAGCTACC CCATATAGAG TGGACACCAG TCTTGGGACA






37851

GAGAGCAGCA CTACTGAAGG ACGCTTGGTT ATGGTCAGTA CTTTGGACAC






37901

TTCAAGCCAA CCAGGCAGGA CATCTTCAAC ACCCATTTTG GATACCAGAA






37951

TGACAGAGAG CGTTGAGCTG GGAACAGTGA CAAGTGCTTA TCAAGTTCCT






38001

TCACTCTCAA CACGGTTGAC AAGAGAATGC GCATGGCGAG AAGGGAGAAG






38051
TGTAGTTGGA TGGATAAAAG GAAGAATGGA GAGAAGAGTG AATGGAAGGA





38101
AGCAAAGATG AAGCGGAGGA AGGATAGATG CACAGAAGGA AGGATGAAAA





38151
GAAAGAAAGA TGATGGAAGA CAGGATTGAA GGGGATATAG ATTGAAGGAA





38201
AGAAAGGTAG AAGGATGAAA TGAAGTAAAG ATTGAAGAAA AGATGGATGG





38251
AAAGAAGAAA GGAGGGTGCA CAAAAAATCT CACACTTCAC CACATATGAT





38301
TCATCCATAT AAGAAAAAAC CACTTGTACC CTCAAAGCTA TTGAAATACA





38351
AACTTTTAAA TTAAAATTTT AAAAAGCAAG AGAAAGGAAA GAAGGGAGGA





38401
AAGACAAAAG GAAGAATGGG TGATAGAAGG AAAGAATAAA AGGAAGAAAA





38451
AATGGAAGAA TAGATGATCA GATCTAGGGA TGAATGAAAG GAAGGATGGA





38501
CAAATCTATA GGTAGGTGGA TGGATCTATG GACAGGTGTG GCCACTTATG





38551
GCACATAGTC CCAGCTCCAG TTCATACTGA TGGACTTGAG GAGTGTTTGT





38601
GGCCAATGAA GTGGATCCAT TTAGACAGTG CTCTTCTTCT GAATGAGATG





Exon 5



38651
AGTTACCCCA GTTTTTCTCC CCACCTTCAT CTTCAGGAAC TGATGGCATT





38701

ATGGAACACA TCACAAAAAT ACCCAATGAA GCAGCACACA GAGGTACCAT






38751

AAGACCAGTC AAAGGCCCTC AGACATCCAC TTCGCCTGCC AGTCCTAAAG






38801
GTAGGTTTAA CTTTGCTTAC CTCCCAGTAA TGCCACTCGT GACCATATTT





38851
CCTCCTCCAG AGAGACAAAA TGTTTGTATT CTTTAGAGAG AGAATTGTGT





38901
GTGGTTGTCA TAGGTTTCCC TGTCTGAACT GAGTCTTTAT CTAATGGTTA





38951
CCAGGCAGAT GTTACCACTG TCTCTTTCTC CTCATGGCAT GCTGAGTGAG





39001
TTTTGTCCAA CATCAAATAT TCACAAATTT GTCCATATTA ACCAAATTTT





39051
AAAAATGCTC ATTAAAAACT TACTATGAGC TGGGCGCAGT GGCTCATGCC





39101
TGTAATCCCA ATACTTTGGG AGGCTGAGCT GGGTGGATCA CCAGAGGTCA





39151
AAAATTCGAG ACCAGTCTGA CCAAAATGGT GAAACTCCAT CTCTACTGAA





39201
AATATAAAAA TTAGCCGGGC ATGGTGGCAC ACACCGTAAT CACAGCTACT





39251
CAGGAGGCTG AGGCAAGAGA GTCACTTGAA CCACAGGAGG TAGAGGCTGC





39301
AGTGAGCTGA GCATTGTGCC AATGCACTCC AGCCTGGGTG GCAGAGCAAG





39351
ACTCCAGCTC AGAAATAAAT AATATATTAT ATATATATAT ATATGTTTTA





39401
TTTAGATGGA ATATACTATA TATATATGTA TATATATATG TATGTATATA





39451
TATATATGTA TGTATATATA TATATATATA TATATATATA TATATAGAGA





39501
GAGAGAGAGA GAGAGAGAGA GAGAGAGACA GAGTATGTCT GAGAATGCAT





39551
CCCGATAGTT CTAGCAAGGT AGGAAAAGGA AGTATCATAA CAGCCTTGAA





39601
GTAGCCTGTT GAAACAGACA GACTCTCTTG TAAGAGAACT CACAAAATCT





39651
AGGATTATAT CTCCCATGAT GAAAAATTTG GAACTGTACA TTTTTGTTTA





39701
ACTGTCACTT AAATNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





39751
NNNNNNNNNN NNNNNNNNNN NCCAGGAGGC ACTGTGCTTG GCGCCTTTTT





39801
ACCAACACTT TGAGATGGCC ATTGTACTTA TCCCCACTTT ATAGACGGGA





39851
AAATGGAGGT CCAGCAATAT TTTTTAACTT AAAGAGCCAC CCATCTCTTT





39901
AGAGAAAGAG CCAGAATCCC AGGCAGGGGC TATCTTATTC CAGAGCCCAA





39951
GCTCTCAAAC ACATGATACA CAATACTTAA TCTCTCTCAA GTCAGAGGAG





40001
ATCCACTTAA GTATACATCC ATCCACATAT TCATTCATTC AATCATTCAA





40051
CAAATATTAG TTGAGCACTT ACCGTATGCC AAACAGTCAA ACGTGAATAG





40101
CTGTTACAAA TGAGACTGTG AAGGATGGTA CAACGCAGAT TCAGACAGTG





40151
TGATAAGGAA ATATTGAGAA GCAAAGATGA GTTCTGGAGT GAATTTGTAA





40201
AGGTGGATGT GGGCTTGGAT TTCAATAATG GCAGAACTTA AGGAATCTGA





40251
TGAGAAGTGG GCACTTCAGG CAGAGAGAAG AGCTTGAACA AGGCTCAGAG





40301
GCTGACAGTG CAGGAAACAC ATGGGAAGAG GGAATAGAGT AGCGGTCAAG





40351
AATTCACAGA GGAGTTATAG GTGAAGATGC AACCAAGTTA CAGACCAAGG





40401
TAAGATAGGG GAATACCAAT CACAATCTCT TTTCCCATTC CAGAAGCATC





40451
CCAGACACAT CCTAGTAACC GAGAGACATT TCTCTCCCTT TCCTCCTGTG





40501
GAGAATAAAT AAGCTATTGC AAGTCCAGTA AGTGTAATCA TTTTGTTCAA





Exon 6



40551
ATTGTGTGCC CATTCCCCAA TTTACAGGAC TACACACAGG AGGGACAAAA





40601

AGAATGGAGA CCACAACCAC AGCTCTGAAG ACCACCACCA CAGCTCTGAA






40651

GACCACTTCC AGAGCCACCT TGACCACCAG TGTCTATACT CCCACTTTGG






40701

GAACACTGAC TCCCCTCAAT GCATCAATGC AAATGGCCAG CACAATCCCC






40751

ACAGAAATGA TGATCACAAC CCCATATGTT TTCCCTGATG TTCCAGAAAC






40801

GACATCCTCA TTGGCTACCA GCCTGGGAGC AGAAACCAGC ACAGCTCTTC






40851

CCAGGACAAC CCCATCTGTT TTCAATAGAG AATCAGAGAC CACAGCCTCA






40901

CTGGTCTCTC GTTCTGGGGC AGAGAGAAGT CCGGTTATTC AAACTCTAGA






40951

TGTTTCTTCT AGTGAGCCAG ATACAACAGC TTCATGGGTT ATCCATCCTG






41001

CAGAGACCAT CCCAACTGTT TCCAAGACAA CCCCCAATTT TTTCCACAGT






41051

GAATTAGACA CTGTATCTTC CACAGCCACC AGTCATGGGG CAGACGTCAG






41101

CTCAGCCATT CCAACAAATA TCTCACCTAG TGAACTAGAT GCACTGACCC






41151

CACTGGTCAC TATTTCGGGG ACAGATACTA GTACAACATT CCCAACACTG






41201

ACTAAGTCCC CACATGAAAC AGAGACAAGA ACCACATGGC TCACTCATCC






41251

TGCAGAGACC AGCTCAACTA TTCCCAGAAC AATCCCCAAT TTTTCTCATC






41301

ATGAATCAGA TGCCACACCT TCAATAGCCA CCAGTCCTGG GGCAGAAACC






41351

AGTTCAGCTA TTCCAATTAT GACTGTCTCA CCTGGTGCAG AAGATCTGGT






41401

GACCTCACAG GTCACTAGTT CTGGGACAGA CAGAAATATG ACTATTCCAA






41451

CTTTGACTCT TTCTCCTGGT GAACCAAAGA CGATAGCCTC ATTAGTCACC






41501

CATCCTGAAG CACAGACAAG TTCGGCCATT CCAACTTCAA CTATCTCGCC






41551

TGCTGTATCA CGGTTGGTGA CCTCAATGGT CACCAGTTTG GCGGCAAAGA






41601

CAAGTACAAC TAATCGAGCT CTGACAAACT CCCCTGGTGA ACCAGCTACA






41651

ACAGTTTCAT TGGTCACGCA TCCTGCACAG ACCAGCCCAA CAGTTCCCTG






41701

GACAACTTCC ATTTTTTTCC ATAGTAAATC AGACACCACA CCTTCAATGA






41751

CCACCAGTCA TGGGGCAGAA TCCAGTTCAG CTGTTCCAAC TCCAACTGTT






41801

TCAACTGAGG TACCAGGAGT AGTGACCCCT TTGGTCACCA GTTCTAGGGC






41851

AGTGATCAGT ACAACTATTC CAATTCTGAC TCTTTCTCCT GGTGAACCAG






41901

AGACCACACC TTCAATGGCC ACCAGTCATG GGGAAGAAGC CAGTTCTGCT






41951

ATTCCAACTC CAACTGTTTC ACCTGGGGTA CCAGGAGTGG TGACCTCTCT






42001

GGTCACTAGT TCTAGGGCAG TGACTAGTAC AACTATTCCA ATTCTGACTT






42051

TTTCTCTTGG TGAACCAGAG ACCACACCTT CAATGGCCAC CAGTCATGGG






42101

ACAGAAGCTG GCTCAGCTGT TCCAACTGTT TTACCTGAGG TACCAGGAAT






42151

GGTGACCTCT CTGGTTGCTA GTTCTAGGGC AGTAACCAGT ACAACTCTTC






42201

CAACTCTGAC TCTTTCTCCT GGTGAACCAG AGACCACACC TTCAATGGCC






42251

ACCAGTCATG GGGCAGAAGC CAGCTCAACT GTTCCAACTG TTTCACCTGA






42301

GGTACCAGGA GTGGTGACCT CTCTGGTCAC TAGTTCTAGT GGAGTAAACA






42351

GTACAAGTAT TCCAACTCTG ATTCTTTCTC CTGGTGAACT AGAAACCACA






42401

CCTTCAATGG CCACCAGTCA TGGGGCAGAA GCCAGCTCAG CTGTTCCAAC






42451

TCCAACTGTT TCACCTGGGG TATCAGGAGT GGTGACCCCT CTGGTCACTA






42501

GTTCCAGGGC AGTGACCAGT ACAACTATTC CAATTCTAAC TCTTTCTTCT






42551

AGTGAGCCAG AGACCACACC TTCAATGGCC ACCAGTCATG GGGTAGAAGC






42601

CAGCTCAGCT GTTCTAACTG TTTCACCTGA GGTACCAGGA ATGGTGACCT






42651

CTCTGGTCAC TAGTTCTAGA GCAGTAACCA GTACAACTAT TCCAACTCTG






42701

ACTATTTCTT CTGATGAACC AGAGACCACA ACTTCATTGG TCACCCATTC






42751

TGAGGCAAAG ATGATTTCAG CCATTCCAAC TTTAGCTGTC TCCCCTACTG






42801

TACAAGGGCT GGTGACTTCA CTGGTCACTA GTTCTGGGTC AGAGACCAGT






42851

GCGTTTTCAA ATCTAACTGT TGCCTCAAGT CAACCAGAGA CCATAGACTC






42901

ATGGGTCGCT CATCCTGGGA CAGAAGCAAG TTCTGTTGTT CCAACTTTGA






42951

CTGTCTCCAC TGGTGAGCCG TTTACAAATA TCTCATTGGT CACCCATCCT






43001

GCAGAGAGTA GCTCAACTCT TCCCAGGACA ACCTCAAGGT TTTCCCACAG






43051

TGAATTAGAC ACTATGCCTT CTACAGTCAC CAGTCCTGAG GCAGAATCCA






43101

GCTCAGCCAT TTCAACAACT ATTTCACCTG GTATACCAGG TGTGCTGACA






43151

TCACTGGTCA CTAGCTCTGG GAGAGACATC AGTGCAACTT TTCCAACAGT






43201

GCCTGAGTCC CCACATGAAT CAGAGGCAAC AGCCTCATGG GTTACTCATC






43251

CTGCAGTCAC CAGCACAACA GTTCCCAGGA CAACCCCTAA TTATTCTCAT






43301

AGTGAACCAG ACACCACACC ATCAATAGCC ACCAGTCCTG GGGCAGAAGC






43351

CACTTCAGAT TTTCCAACAA TAACTGTCTC ACCTGATGTA CCAGATATGG






43401

TAACCTCACA GGTCACTAGT TCTGGGACAG ACACCAGTAT AACTATTCCA






43451

ACTCTGACTC TTTCTTCTGG TGAGCCAGAG ACCACAACCT CATTTATCAC






43501

CTATTCTGAG ACACACACAA GTTCAGCCAT TCCAACTCTC CCTGTCTCCC






43551

CTGGTGCATC AAAGATGCTG ACCTCACTGG TCATCAGTTC TGGGACAGAC






43601

AGCACTACAA CTTTCCCAAC ACTGACGGAG ACCCCATATG AACCAGAGAC






43651

AACAGCCATA CAGCTCATTC ATCCTGCAGA GACCAACACA ATGGTTCCCA






43701

GGACAACTCC CAAGTTTTCC CATAGTAAGT CAGACACCAC ACTCCCAGTA






43751

GCCATCACCA GTCCTGGGCC AGAAGCCAGT TCAGCTGTTT CAACGACAAC






43801

TATCTCACCT GATATGTCAG ATCTGGTGAC CTCACTGGTC CCTAGTTCTG






43851

GGACAGACAC CAGTACAACC TTCCCAACAT TGAGTGAGAC CCCATATGAA






43901

CCAGAGACTA CAGCCACGTG GCTCACTCAT CCTGCAGAAA CCAGCACAAC






43951

GGTTTCTGGG ACAATTCCCA ACTTTTCCCA TAGGGGATCA GACACTGCAC






44001

CCTCAATGGT CACCAGTCCT GGAGTAGACA CGAGGTCAGG TGTTCCAACT






44051

ACAACCATCC CACCCAGTAT ACCAGGGGTA GTGACCTCAC AGGTCACTAG






44101

TTCTGCAACA GACACTAGTA CAGCTATTCC AACTTTGACT CCTTCTCCTG






44151

GTGAACCAGA GACCACAGCC TCATCAGCTA CCCATCCTGG GACACAGACT






44201

GGCTTCACTG TTCCAATTCG GACTGTTCCC TCTAGTGAGC CAGATACAAT






44251

GGCTTCCTGG GTCACTCATC CTCCACAGAC CAGCACACCT GTTTCCAGAA






44301

CAACCTCCAG TTTTTCCCAT AGTAGTCCAG ATGCCACACC TGTAATGGCC






44351

ACCAGTCCTA GGACAGAAGC CAGTTCAGCT GTACTGACAA CAATCTCACC






44401

TGGTGCACCA GAGATGGTGA CTTCACAGAT CACTAGTTCT GGGGCAGCAA






44451

CCAGTACAAC TGTTCCAACT TTGACTCATT CTCCTGGTAT GCCAGAGACC






44501

ACAGCCTTAT TGAGCACCCA TCCCAGAACA GAGACAAGTA AAACATTTCC






44551

TGCTTCAACT GTGTTTCCTC AAGTATCAGA GACCACAGCC TCACTCACCA






44601

TTAGACCTGG TGCAGAGACT AGCACAGCTC TCCCAACTCA GACAACATCC






44651

TCTCTCTTCA CCCTACTTGT AACTGGAACC AGCAGAGTTG ATCTAAGTCC






44701

AACTGCTTCA CCTGGTGTTT CTGCAAAAAC AGCCCCACTT TCCACCCATC






44751

CAGGGACAGA AACCAGCACA ATGATTCCAA CTTCAACTCT TTCCCTTGGT






44801

TTACTAGAGA CTACAGGCTT ACTGGCCACC AGCTCTTCAG CAGAGACCAG






44851

CACGAGTACT CTAACTCTGA CTGTTTCCCC TGCTGTCTCT GGGCTTTCCA






44901

GTGCCTCTAT AACAACTGAT AAGCCCCAAA CTGTGACCTC CTGGAACACA






44951

GAAACCTCAC CATCTGTAAC TTCAGTTGGA CCCCCAGAAT TTTCCAGGAC






45001

TGTCACAGGC ACCACTATGA CCTTGATACC ATCAGAGATG CCAACACCAC






45051

CTAAAACCAG TCATGGAGAA GGAGTGAGTC CAACCACTAT CTTGAGAACT






45101

ACAATGGTTG AAGCCACTAA TTTAGCTACC ACAGGTTCCA GTCCCACTGT






45151

GGCCAAGACA ACAACCACCT TCAATACACT GGCTGGAAGC CTCTTTACTC






45201

CTCTGACCAC ACCTGGGATG TCCACCTTGG CCTCTGAGAG TGTGACCTCA






45251

AGAACAAGTA AGAATAACTT TTTTATTGTG GTAAAATATA AATACTATAA






45301
AAATTGCCAT TCTAAACATT TTAATTGTAC AACTCAGCAG TACTAATACA





45351
TTCACATTGT TGTGCAACCC TCACCACTAT CTGTTTTCAA AACTTTTTTT





45401
ATCACCCCAA ACAGGACTGA AGGAATAATT TCCCATTCCC CATTCTCCCT





45451
AGTGCAGTGG TGCAATCTCG GCTCACCACA ACCTCTGAAC CTCTGTCTCC





45501
TGGGTTCAAG CAATTCTCCT GCATCAGCCT CCTGAGTAGT TGGGACTACA





45551
GGTGCACGCC ACCGTGCCTG GCTAATTTTT GTATTTTTAG TACAGACAGG





45601
GTTTTACCAT GTTGGTCAGG CTGGTCTCAA ACTCCTGACC TCAGGTGGTC





45651
CACACGCCTT GGCCTCCCAA AGTGCTGGGA TTACAAGTGT GAGACACTGT





45701
GCCCGGCCAT ATCTGTTAGA TCTTACTAAT CCTGTCAAGA GGATTCAGTG





45751
TCCTTTTTTT TTTTTCTTTC TTTTTTTTGA TAGAGTCTCC CTCTGGCACC





45801
CAGGCTGGAG TGCAGTGGTA CGGTCTTGGC TCACTGCAGC CTCCACCTCC





45851
CAGACTGAAG CGATTCTCCT GCCTCAGCCT CCCGAATAGC TGGGACTACA





45901
GGCGCGTGCC ACCACGCCCA GCTAATTTTT GCATTTTTAG TAGAGATGGG





45951
ATTTCACTAT GTTGGCCAGG CTGGTCTCAA ACTCCTGATC TCAAGTGATC





46001
CGCCCAAGGG CCTCCCAAAG TACTGGGATT ACAGGTAGGA GCCACCTCAC





46051
CTGGCCCTAT TTTCGGAATG GATTTTTTTT TAATGTTTAA AATGTCACCT





46101
AAGATTATTG TGAAGATCAA ATAAGATAAA ATCCTAATAA CCCAAGTAAA





46151
CCACAGGGCT CCACTTGGAC CAGTCTCAGA AGTTTCAAGA AAATCAGTCA





46201
GACCATCAAA TGTAAAATAA GTCTAAATTT TCTTTGCACT ATTCACAGAG





46251
TGCCAAAGAG GATCTAATTC ATGTTTCAGA ACATACCCTA CTTACTAAAA





46301
TCCCCTTTTC CTCATTTCTT CTCATTCTGC AACTTTATCA TCTCCTGCGG





46351
ACCCCCTAGC CTCTCCCCTC CCCATAGTCA GTCTCTCTCT CTCTCTTTCC





46401
CTCCCCTCTT ATTATCTCAA TTTCACACGA AAGAATTCCA GAAACTATAC





46451
TGCCAAAAGT CTTTCCTGTC TTTGAAAAGT TGGGAAAGAG GAGAAACTCA





46501
GACAGCAATG ACAAAATTAT ACGTAATGGA TGAAGGAAAC ACAAATAAGG





46551
CTGGAAACAG AAAATTTTGT CCCCATCATT TATTTAATGA AGGTGGCAGT





46601
ATTCCAGCCA CATAGTGAAC CCCCACAATA AGAAGGGGCC TCTGGCGATT





46651
GATTATTGTC ATTGTTGTTA ATGATAATGA GGGTGAGGAT ATCATGAGCA





46701
TCAGTGTAGG AGGCAGTTAA CTAATAAGAC CAAGCTGTTG GCTGGGCGTG





46751
CTGGTTCACA CCTGCAGTCC CAGCACTTTG GGAGGCCAAA GTGGGTGGAT





46801
CACTTGAGGT CAGGAGTTCA AGACTAGCCT GGCCAACATG GTGAAACCTG





46851
GTCTCTACCA AAAATACAAA AATTAGTCAG GTGTGGTGGC GTGTGCCTGT





46901
AATGACAACT ACTTGGGAGG CTGAGGCAGG AGAATCACTT GAACCTGGGA





46951
GGCGGAGGCT GCAGTGAGAT GAGCTTGAAC CACTGCACTC CAGCCCGGGC





47001
AACAGAGAGA GACTCTTGTC TCAAAAAACA AAACAAACAA ACAAAAACTA





47051
AACCAAACAA AAAAAGACTA GCTGTTATTC ATTTATTTAT TTATTTATTT





47101
AGAGACGGAG TCTCGCTCTG TCACCCAGGC TGGAGTGCAG CGGCACAATC





47151
TTGGCTCACT GCAACCTCTG CCTCCCAGGT TCATGTGATT CTCCCGCCTC





47201
AGCCTCCCCA GCTGTTGTTA TTCATGAATG AACCTCAGAG AAAGCACACA





47251
GGAGGGTTGG TGCACCTGTG TTTTGAGTTC TACCCCTCCT TCCTCTCTTA





47301
ACTTCCTCCT GTCTTCTCAC TCTGATTCGT TCTTCCTTCC TCTCCCTCTC





Exon 7



47351
TCTCTGCAGG TTATAACCAT CGGTCCTGGA TCTCCACCAC CAGCAGTGAG





47401
TAAACATGGC CCTGAAGTCC CTATGCCCTG GGAATTCTTC CTCCCTAAGC





47451
CTGCCTTCCA GGAGGAAAGT ATCCCCCATT CCCTAGGTTC TCATCCCCAC





47501
AGAAACTCCA GAATAGCAAA AGTCTCAGGC TGAGCCAAGG CACAGATGCC





47551
AGTGCTCACC AAGAGTCCTA TTCTCCCCTC GCTAAATGAT AGGACCCAAC





47601
AAACCCGATT CACGCTGCGT TTTCTTTCAG CTCCGATGAC CTCCATGTTC





47651
TCTCCAAGGC CTCTCGTATC TGTGAGCCCC ACCCCCAGCG CTACAGGTAG





47701
GAATCTGGCT TCCAGCTCCC ATGAAACGTC GGCTGCCATT CAGTGGCTGA





47751
TTAATTGCTG TGTGGTCTGA GTCCTGATGC CCACCAAGTC TCAGCGTGTT





47801
CCCCTCTGTC CAATCTCATC CAACAATTTA AGCTAATGCT TGTTTAATGA





47851
TGTCCTCACT ATACCACCTT GGACACTTTC TTTTTGCCTG GATTTAAAGC





47901
TTCCATTTCT TTCCTTCCTT CCTTCTTTTC TTCCTTCCTT CCTTCCTTCC





47951
TTCCTTCCTT CCTTCCTTCC TTCCTTCCTT CCTTCCTTCC TCCTTCCTTC





48001
CTTCCTTTCT TCCTTTCTTC CTGTCTTTTT CTTTCTTTCC TTCTTTTGGC





48051
AGAGTCTCAC TCTGTCGCCC AGGCTGGAGT GCAATGGTGC AATCTCGGTT





48101
CACTGCAACC TCTGCCTCCC AGGTTCAAGC GATTCTCATG CCACATGCCA





48151
CTATGCCTGG CTAATTTTTG TTTTTTTGTT TTTTGGGGGG TTTTTTGAGA





48201
CAGAGTCTCA GTCTGTTGCC CAAGCTGGAG TGCAGTGGCA TGATCTCGGG





48251
TCACTGCAAC CTCCTTCTCC CAGGTTCAAG CGATTTTCCT GCCTCAGCCT





48301
CCTGAGTAGC TGGAACTACA GGCACGCACC ATCACACCGG CTAATTTTTT





48351
GTGTTTTTAG TAGAGACGAC GGTTTTGCAA TGTGGGCCAG GCTTGTCTCG





48401
AACTCCTGAC CTCAAGTGAT CCTCCAGCCT CGGCCTCTCA AAGTGCTGGG





48451
ATTACAAGTG TGAGCCACTG CACCAGGCCA AAAACTTGTA TTTCAATAGT





48501
CATTGAGGCT GGGTGCAGTG GCTCACGCCT GTAATCCCAG CACTTTGGGA





48551
GGCTGAGGCC AGTGGATCAT GAGGTCAGGA GATCAAGACC ACCCTGGCTA





48601
ACACAGTGAA ACCCCATCTC TACTAAAAAT ACACACAAAA ATTAGCCGGG





48651
CATGGTGGCA AGATGCCTGT AGTCCCAGCT ACTCAGGAGG CTGAGGCAGG





48701
AGAATGGCGT GAACCTGGGA GGCAGAGCTT GCAGTGAGCG GAGATCGCAC





48751
CGCTGCACTC CAGCCTGGGC AACAGAGAGC GACTCTGTCT CAAAAAAAAA





48801
AATATATATA TATATATATA TATATTCATT GAGACCGACT CTGACTTAAA





48851
AGCAGTAATG AATGGTGTAG GTTTTGGTAA ATTACAGGTC TTGCTTTAAG





48901
TCCTGGTCCT CTCTTTTGCT CACTGTGTGG CCCCGGAAGA GCCATGTAAC





48951
CTCTCCAGGC TTCAGTGTCC ATTTTTAGAA CGGAGTAAGT GAATAAGCTG





49001
TGTCCAATCA TCTCTGGCCA TATCAGCTTC ATTTTTTTTT TCCTCCAGGG





49051
TCCAAACATC CCTCCACCCT CAGAGTCTTT GCACCTGGTG TTCTTGTCCT





49101
TCAAATCTCA GCTTGGATCA CCCTTTATAA AGTAGCATTT CCCCCGTATA





49151
CGCATCTTGC ACACAGCCAA TCTCTATTCT ACCTCTATGC TCACTTCCTT





49201
CCTGGCAATT ATTACTACAG CTGGGCCCTT GAACAGCATG AGGGTTCAGG





49251
GTGCTGACCC CTATGCATTC AAAAATCCAC ATATAACTTT TTTTTTTTTG





49301
AGATGGAGTT TCACACTTGT TGCCCAGGCT GGAGTGCAGT GGCGCCATCT





49351
TGGCTCACTG CAAACTCTGC CTCCTGGGTT CAAGTGATTC TCCTGCCTCA





49401
GCCTCCTGAG TAGCTGGGAT TACAGGCATG TGCCACCATG CCCAGCTAAT





49451
TTTGTATTTT TAGTAGAGAT GAGGTTTCTC CATGTTCGCC AGGCTGCTCT





49501
TGAACTCCTG ACTTCAGGTG ATCCGCCTGC CTTGGCCTCC CAAAGTGCTG





49551
GGATTACAGG CATGAGCCAT GATGCCCGGC CATTTGCTAA TGGCATCTAG





49601
TAAGTAGAGG CCAGAGATGT TGCAAAACAT CCAACAATGC ACAAAGCAGC





49651
CTCCTATCAA AACACATTAT CCAGACCAAA ATGTCAATAG GGCTGAGGTT





49701
GAGCATCTGC TGTACACAGA TTCCAAGTTC TGGTACAAAT CTCGTAGTTC





49751
TCTGAGGGCT CATCTTTCAA TGCCTAGCAC ATCAAAGGAG GCCAATTTCC





49801
TCTTCCCTTT CACCTCCTGG TATGAAATGT TTCCTCCTCC ACCTTGATCC





49851
TGTAAGAGCC CAGCTGGAGT TTGCAGACGA CGGGGAAAGA AATGGGTGAG





49901
GGAGGGTCCT ATGGTTGAGT CTCCGCAGTG GGCCCTGGGT GCCCAGTTCA





49951
CCCTCCTCCC CTTCATTTTC TCCATCATGA CAACTCAAGG CAAATTCTCA





50001
GTTTCCATGG GCCAGTGGAA TCCACTGACT TCATGAAATA ACCCCACCCT





50051
GAGCAAATAC CCCTCAAATA ATAACTGTTT ACACAACATC AGTGGCAACA





50101
ATGACCCAAG CAGCAATGCC ACCACCAGAA TAGCAACCAT AACAGCAGCT





50151
CATTTTCATC AAAAGGAAAC TGTAGGGCCA GGCACAGTGG CTCACACCTA





50201
TATTCCCAGC ATTTTGGGAG GCTGAGGCAG GCAGATCACC TGAGGTCAGG





50251
AGTTCAAGAC CAGCCCAGCC AACATGGTGA AACCCCATCT CTACTAAAAA





50301
TACAAAAACT AGCCAGGCTT GGTGGCATGT GCCTGTAATC CTAGCTACTC





50351
GGGAGGCTGA GGCAGGAGAA TTGCTTGAAC CTGGGAGGCA GAGGTTGCAG





50401
TGAGCTGAGA TTGTGCCACT GCACTCCAGC CTGGGCGACA GAGCAAGACT





50451
CCGTCTGAAA AAAAAAAAAA AAGGAATTGT GCCAGGAATT GTGATGAGAA





50501
CTTTATATGC ATTATCTCCT ATTAATATTA CCCAAACCTC CGTGAGTTAG





50551
TATACTCATT TCTACAGAGA GCATTTATGC ATCCAGGGAG GAAGTAATTA





50601
GCCCAGAATT ACTCAGTTAT GACACAGGAC AGTATGAAAA CTCCAACCGA





50651
AGATTGGAGA CTCATGAAAA CTCCAGGCTC CTAACTACAA GACATCACTG





50701
TGGATCGTCC AAATAGAGCA AGCCCCAATC TCAGGACAGG AATGAGGCAT





50751
GAATGGCCTC TATGCTAATG ATCTAACCTA ATGCTGAATT TGTTACTTCC





50801
CTTCTGAATC CACTTGGAGA TTTCCTTTAT ATCTGACTTG AAATAGAGGA





50851
TATATACTCC TCTATCCTTG ACATAGGAGA TAATACACAG AAAGTATTTC





50901
ATTGTAGTAT CAAGTACACA TCCTGTTCTG TGTCCATAGG ATTATGACTA





50951
ATTTAGGGCA TGGCTTAACA GTGTGGTACT ATTGAATGAC AGACAGATGT





51001
CTGTTTTGTT GGATGCAGGA CAAGCCATGT AACCTCCCCA GACTTTAGTG





51051
TCCCCTCTGT GGAATGGAAT AAAAATACTA CGTGGGATTG TTCTGATAAT





51101
CAAATGAGAT AATTCAGGAA CAACCCAGAT AAATAACAGG GCTGCCCTGG





51151
GTTCTGTCTT TCCTTGTATC TCTCACAGAG CCTCAAAGGA GATGCAATCC





51201
ATGACCTAGA GAAACACTCA GGACAAATTC TCTTTTCCCC AGTTCCTTTC





51251
TTGCTCCAAT GGCAACACCA CCCCTCTCAT CCTGAAGTCT CTTGTTTTTA





51301
CCACCACACC TATTTTGCCA AATTTTCTCC AATATTCCAA ACCATATGAA





51351
ACCTTTCTTT CTTTCTTTTC TTTCCTTCCT TTCCTTCTTT CTTTCTTTTT





51401
TCTCTTCTTT TCTTTTCTTT TTGAGACATG GTCTCACTCT GTTGCACAGG





51451
CTGGAGTGCA ATGGCACGAT CTTTGCTCAC TGCAACCTCC GCCTCCCAGG





51501
TTCAAGAGAT TCTCTTGCCT CAGCCTCCTG AGTAGCTGGG ATTACAGGCG





51551
CCCACCGCCA CGCCACGCTA ATTTTTGTGT TCTTAGTGGA GACGGGGTTT





51601
CGCCATGTTG GCCAGGCTGG TCTTGAACTC CTGACCTCAA GTGATTTGCC





51651
CATCTCGGTC TCCCAAAGTG CTAGGATTAC AGGCGTGAGC CACCAAGCCC





51701
GGCCCCATAT GAACCGTTTC TATCCCTCAT TTCTCTGTAC TTTTACCTAA





51751
AAACACCACT CCCTTCACCC ATCACATTTT TGTCAATTCT ACATCACACA





51801
CACACACACA CACACACACA CACACACAGA GAAAGTAAGT TGGAAAAAAA





51851
TTATACTATC ATGAAATTTT GTGAAAGGAG GTAAGCTGAG AGAGTAAGAA





51901
TCAAACTAAA TTATCTTTAT GGGTAGAAAG CACACTCATC CATACATGTG





51951
TCTTTCCACC CTTGTAATGT ATTTATTATT ATTGTTTGTA TATACTAGAT





52001
TCCCAATAAA TAGGGACAGC TATTATGGTA TTTTTATTTC AGGAATAATA





52051
ATAGTGATGA TTTCCACCAT TATTGTCAAA GGACAAAGCA CAAAATATGT





52101
ACCAAATAAA ATATAGCCAT TATCCTTTAT TCACAAAAGA TCTTGGCCCC





52151
ACCTCTTCTC AATGAAATGT CCATGACTTG TTCAACTTTG GCCACTCTGG





52201
GCTGAGAGAT GGAGGTTCCC TTGCGAGCTG AAGTCACACA TCGAAGGTGG





52251
AAGCCCCTCC CCTCCCTCTG GCTGGCTGAG GGATAGCCCA GATGGGCTCA





52301
TCATGAAAGT TTCCCATTAT TTCCATTTCT GGATCTACCA TCTTCCCCTC





52351
CCCTACCTCT CACCCATCAT AATTGTCCTT CTTTACTCTT TCCTCCCTAT





Exon 8



52401
CTGCAGGTTA TAACCGTCGG TACTGGACCC CTGCCACCAG CAGTGAGTAT





52451
TCAAACCTGT GATATTCCAA TGCCCTTGGG ACCCTTCCTC CCCAAGGTGC





52501
ATTCCTCAGA AGAGAAACTG ATCATTCTCC CTCCCTACGT GCCCAGCCAC





52551
AGCCTCAGAG CAGCCCCTAA CCCGTCAAGG TCTTGGTGTG AGTCAAGATA





52601
GAAGTCCAAA TTCCAATGAG CAGTTCCTGT CCCATATTCC TTTAGGAAGA





Exon 9



52651
CACCCAATCA TTTCTCCATG TTCTTTTTTT CTCAGCTCCA GTGACTTCTA





52701

CATTCTCCCC AGGGATTTCC ACATCCTCCA TCCCCAGCTC CACAGGTAGG






52751
AAGCTCCTCT CTGGCATCTA TGAAATTTAA CACTGCATGG TCTGTTCCCT





52801
GCTGACCACC CAGACTCAGC CTGTTCCACT CGCCCTCTCA CTCTCTCTCT





52851
CTCTCTTTTT TTTTTTTTTT TTTTTTTTTT TTTACGGAGT CTTGCTCTGT





52901
CACCCAGGCT GGAGTGGAAT GGTGTGATCT CGGCTCACTG CAACCTTCGC





52951
CTCCCAGGTT CACGTGATTC TCCTGCCTCA GCCTCCGGAG TAGCTGGGAT





53001
TACAGGTGCA CACCACCATG CCTGGCTAAT TTTTTGTATT TTTAGTAGAG





53051
ACGGGGTTTC ACCATGTTGG CCAGGCTGGT CTTGAACTCC TGACCTCAAG





53101
TGATCTACCC ACCTTGGCCT CCCAAAGTGC TGGGATTATA GGCATGAGCC





53151
ACCACGCCAG GCCCACTCTC TAAATTTTGA CCACCCTGCC TTGAGTGGTC





53201
TTCTAGCACC CTAACCTCTG TCTAACCTCG AGAGCTTTGC ACTAGCGATT





53251
CCTGGGGACC AGCTATGGTT GGTATCTTCT CAACTTTCTA ATTTTTTTAA





53301
AATTATTATT ATTATTATTA TTATTTTAAA TGGAGTCTCG CTCTGTCACC





53351
CAGGCTGGAG TGCAGTGGCA CCATCTCGGC TCATTGCAAC CTCTACCTCC





53401
CGGGTTCATG CAATTTTCCT GCCTCAGCCA GAAATTTTCT CAGTGGTCGA





53451
GATTGTGCCA CTGCACTCCA GCCTGGGCAA TGGAGCTAGG CTCCATCTCA





53501
AAAAAAAAAA AAAAAAGACG GAGGTCGGGC ATTCCTAACC CTTAACCCTG





53551
CCTTGTGATT CTGGAGTTAT GAGATAGAAC CTGGTGTCCC GTAATTAAAA





53601
TTCCGCCTTC AGGCCTTATG TTTTGTGAGT CACAACACTG CAAACTTTTT





53651
ACATGCTGTA GACAGGATGT TCACTCTCCA CTTCCTCACT GCTCTGCTCT





53701
AATCAATTCA ACCATTTATG TGACATGCCT AACCCCTCTG GGCTTGTACG





53751
TATGTAACAT GTATTACAAA GCAAGTCATT CCATGATCAA TGCTGTCACT





53801
TTTTCTAGGT GCTTTCAAAA TTTGTTCTTC ATCATTGATT TTCAGTAGTT





53851
TGATTACGAT GTGTCTGGGC ATGGTTTTCT TTGAGTTTAT CCTGCTTAAA





53901
GTGTTCTCAG CTTCTTGAGT CTCAAAGTGT TTATTTTCTG CTCTGATTCT





53951
TTCTCCCCTT CGGACCTCCA ATGAAATGAT GTTGCCCGAA GAGACCCTGA





54001
GGTTCTGTTC ATTTTGTTAT TTATCAATCT TTTTTCCTCT CCGAATTTCA





54051
GGTTTAATAA TTTTTTTTTT TTTTTTGAGA CGGAGTCTCG CTCTGTCGCC





54101
CAGGCTGGAG TGCAGTGGCG CGATCTCGGC TCACCGCAAG CTCCGCCCCC





54151
TGGGTTCACG CCATTCTCCT GCCTCAGCCT CCGGAGTAGC TGGGATTACA





54201
GGCACCCGCC ACCATGCCCG GCTAATTTTT TGTATTTTTT AGTAGAGACG





54251
GGGTTTCACC GTATTAGCCA GGATGGTCTC AATCTCCTGA CCTCGTGATC





54301
CGCCCGCCTC AGCCTCCTAA AGAGCTGGGA TTACAGGCGT GAGCCACTGC





54351
GCCCGGCCCA GGTTTAATAA TTTTTATAGA ATATTTTCAC AATCACCAAG





54401
CCTTTTCTCT ACCAGCTCCA TTCTGCCCAT CCATTGAATT CTTTTTATCT





54451
CAGTTACTTT ATGTTTCAGT TCGAAAGTTT CTACTTGGTT AGATAGATAG





54501
ATGTTATATC ATATATTATA TGTTATATAA AAATATATTT ATGGTTATAC





54551
ATATAACATA TATGTTATAT ATAGTTATTT ATATAGCCAT AACTATATAT





54601
AGCCATATAT ATAGTTATAT ATAACCATAT ATATAGTTAC CATATAGTAA





54651
CCACATATAT AAAACATATA TATATAGTGT CTCTCTATAT ATAGTTATAT





54701
ATATAGTTTC TATATCTGTA ACTATATATA GTTATATATG TATGTTTCTC





54751
TGTATATAAA TATATATATT TCTATATATA TAGTTATACA CATTATATAT





54801
ATAACTGGGA GATGTTGGTA AAGGATGGCG TGAGGAAACC TGGAGCAGTC





54851
ATGGTAATCC TCGCTCTGCT CCGAACTCCT CAAGAGCAGG AGAAGGGTCC





54901
TCCTCATTCT CCAGCCATGT TGACTTTGAG CAATTTACTC ATCCTCTCAG





54951
TACCTCAGTT TCCTCACCTG CCAATTGAGG ATAATAATAT TTCATAAATT





55001
GTTTGCAAAT GTTATATGCA ACTCTACGTA AGAACACCTA GCACAGGGGC





55051
TACCAGGGAA TTTGGTTTAA CAAATATTTA TCAGGCACCT ATTCTGGGCT





55101
GGGCAGGGGG GATAAGATGT TGACTAAGTC AAATGCAGTC CCTCCCCTCA





55151
CCAAGTTTAC AGTGTATTGG GCAAGACTGA AATGGAACAA GCAATTACAA





55201
TTGACAATAA AAGACAACCA AGTTATTGAG CACTTACTAT ATGGCATGCC





55251
ATATGCTATG TATTTTTTTT ATTTTTAACT TTTCATTTTG AAATAAATAA





55301
TAAATATAAA GTAAATAATA ATATAAATAA ATAATAAATA ACTTTTCATT





55351
TTGAAATAAA TAATAAATAA ATTCAGGAGA TGTTGCGAAA ATAGTGTAGC





55401
ATTCCCCTGT ATCCTTCACC CAGTTTCTCC CCAATGGCTA CATCTTACAT





55451
AACTCTAATA CAATATCAAA AGCAGGAAAC TGACATTGTT AAAATCCATT





55501
TTACTGGTTT TACACGCGTG TGTGCATATG TGAGCTTGTG TATGTGCGTG





55551
TGTGTGCAGG CATGTGTGTG CATGCACGCC TGTGTGTGCA TATGTGCATG





55601
TGTGCATGCG TGTGTGCATG TGTGCATGTG TGTGTGCATG CGTGCGTGCG





55651
TGCGTGCATC TGTGTGCATG TATGCACATG TGTGTGTGTC TGTGCACGTG





55701
TGTGCATGCA TGTGTGTGTG CGTGTGTGTT GGTAGCCCTA TGCAATTTTT





55751
ATCACATGGG CATAGCCCTA TAATCACCAC CACCATCAAG ATTCAGAACT





55801
GTTCCATTCC CCCAAAGATT CCCCTCATGC TAGCCTTCGT AATCATGCCC





55851
ACTGAGCCCA ACACTATTGC ATAGAATAGC TATTCTACTC TCCATCTCCA





55901
TCTCTGTCTC TACAATTTTC TTTTGAAGAT GTTATATAAA TGGAAATGTA





55951
CAACATGTCA CCTTTGAAAT TGGCTTCTTT TCCACTCAGT GTAATGCCCT





56001
GGAGATGTGC TCTTTTTAAC AGTCATGTAA CCTTCCTAAT TTCCCTCCAA





56051
AATATCATTA TGCCCCTCGC CGCCTTTTTT TTTTTTTTTT TTTTTTGAGA





56101
CAGAGTCTCG CTCTGTTGCC CAGGCTGGAG TGCAGTGGTA TAATCTCAGC





56151
TCACTGCAGC CTCCGTCTCC CGGGTTCAAG GGATTCCCCT GCCTCAGCCT





56201
CCCAAGTAGC CAGGATTACA AGTGCATGCC ACCACGCCTG GCTAATTTTT





56251
GTATTTTTAG TCGAGACGGG GTTTCATTGT GTTGGCCAGG CTGGTCTCGA





56301
ATTCCTGACC TCAAGTGATC TGCCCGCCTT GGCCTCCCAA AGTGCTGGGA





56351
TTACAGGTGT GAGCCACCGC GCCCGACCCA TATTGCCCAT TGTATTACAG





56401
CGGAAGAAAC TGAGGTATGG ACAGGTAACA TGTCCATGGT CACTTGGCTG





56451
GTGAGGGGCA GAGAGGAGAT TTGAAACCAA ATCTGACTCA CTAGTGTGGC





56501
CGTAACCATG GTAACTATGT CTCTCTACCA TGTGGTCTCC TCTTTATTAA





56551
AGGAAGGGCA AGTTCTGGGA GTTTTGGGAG TTTTGGGCTT GAGTGGGGAA





56601
GGGTAGCCAA GTAAAGCAGG TGAGAGAAGG TCTGCTTTAA GGACTGCTGT





56651
TTGATTTTTA TTGTTGTTGT TCAGTGTTCA ATGGGATTGA GTTGACTCTT





56701
TTTTCCCTTC TTGTTCCCCA AAGCATGAGA CTGTTCCGGT CCTTTTCCCT





56751
TTTAACTTCT CAGCTAGAGT TTGTTAGGGC GGGTATGGGC ACCTGGCAGA





56801
GTCTGAGACC TCAGCTTCCA GTAGGCACAC GTTCTGACCC AATACACCTA





56851
CCCTGGTCCC CTAACCTGCT TCTGGTCCCC TAACCTGCTT CTGGGCCCAG





56901
GTAATGCATT TTAGGAACAT CCCACTTTTC TCCTTACCTG GCTTTCCATT





56951
ATCCGTCCAA ACTAAAGCAC CCACCTGTCT GCTTCAGACT CTTGCTTCAA





57001
GCACTCCGTC TGGGTCCTCA GAAATTGACT TACAGTCAGT TCAGATCTGA





57051
CTCAGGCGTG GCCTTCTTTT CTCCTTCCTT GC
















TABLE 2





Genomic Repeats


(SEQ ID NO: 2)







Exon R1








1

AGCAGCCACA GTCCCATTCA TGGTGCCATT CACCCTCAAC TTCACCATCA






51

CCAACCTGCA GTACGAGGAG GACATGCGGC ACCCTGGTTC CAGGAAGTTC






101

AACGCCACAG AGAGAGAACT GCAGGGTCTG GTGAGAGCCC CGCCCACCGT






151
ACTCCTCCCT CGCCCACTTA GACAAACCAG CCCACCTCAC ACTGCCTCGC





201
CCACTGATGC CAGCCACGCC CACCTCATCC AACCCCAGAC ACCTTTCCCT





251
GCCCCACCCA CTGATTTTAG CCAAGCCCAC CTCACCCCAC CCAGCCTACT





301
GATGCCAGCC ACGCCCACCT TTCCCTGCCC CGCCCACTGA TTTCAGCCAC





351
GCCCACCTCA CCCTGGTCCA CCCCTCCAAT GCCCCACTCT TCCTGGCTTC










Exon R2








401
CCGCAGCTGT TGTTTCTCAC CTCCCCTCTC CTTCCTTGCA GCTCAAACCC





451

TTGTTCAGGA ATAGCAGTCT GGAATACCTC TATTCAGGCT GCAGACTAGC






501

CTCACTCAGG TGAGACGCTC CTTAAGAAAA ACACAGCCCA ACAGGTGAAT






551
ATGACCCTAG TCTCTGGGCT CCCTGACTCT GTTCATACTT GGAACAACTA





601
TTGCCCATGG ATACTAAGCA TCACCACCAG CAGCAGCAGA TAACTATTCC





651
TAAGACCCAA GGCACTGCAT TATGTACTTT ATATTTAATG CCTCATCAGT





701
GCTTGCAACA GCCTCATGAA GCAGGAGCAG AAGGGGAAAC TGAGGCCCAG





751
ATTAAGTGGC TTGTGCCAGG ACACACAAAG CAACTGCAGC ACTTCAGGTT





801
CTATATCCAA ACTCCTATCC CTTAGGTGGC ACTTCCTCCT CTGCCCCCAT





851
TATGAACTTG CAGCATGTGG AAAACCCCAA TCTGACTTCC CTCTAAGGGA





901
ACTTGCCCAG AGAATCTAAG AGGGGAGGAA AGGAAGGCGT TCAGCCCTTA





951
CAGGCAGGAG GTCAGCTCCT GAGTGGCTCA GATGCAGCCA CAGAGGGCCT





1001
GGCCGGTCTG AGGGTGACTG AGAGGCACCG AGGGCACTGT CCCTGAGTGC





1051
TGGAAAGGGC AGGTCTTTTA GGGTAGACAG CGGTTGATAT CATTTCCTGC





1101
CTGGCATTCT CACCTTCCAC ACCTCTCTCA CAGAATCTCC AAGTGTGGCT





1151
CTCCCAAGAG AGAGTGTCAG TCATCTACCT CCAGCTTCCT TTCCTTCCCA





1201
GGGGGAAGAG GGGACAGGGG GGCCCTAGTG GCTAAGAGCA TTGGTGAACT





1251
CAGGCAGACC TCAGTTCTGA ACCAACCCAG CTCTGCCATT TACTATCTGT





1301
GACTCTGAGC AAGTGCCTGA AGCCTTCTGT GCCCTATTTC CTGACATATT





1351
ATATATATAA AATACATATA TTATATATAG ACATATTTTA TATACATATT





1401
GAGGCATATT TTATAAACAT GTTTATAGAC ACATTTTTAT ATGCATATGT





1451
TATATACGTA TATAACATAT GTTATATATA ATGTATATAT TATACATATT





1501
GTTATATTGT ATACATGTTA TATATGTTAT AGCATATATA GTACAAGTTA





1551
TATATAACAC ATACATTATG TTACATATAA TGTATATGTT ATATATGATA





1601
TATTATATAT AATTATATAT TATATAAAAC TGTTATATAT AATTATATAT





1651
AATATATAGT TGTTATATAT AATTATATAA TTGTTATATA TTATATACAA





1701
CATATAACAT ACATTATATA TTGTTATATA TAATATAATA TATACATATA





1751
TAACATATGT ATAACTTTTA TGTTATACAT AATGTATATA ACATATATGT





1801
GTATGTGTGA TGTACATAAC ATATCTGACA TTAACATATA ACATATGATA





1851
TAACAATATT ATATGTTATA ACATAATATA TGTTATAATA TAACAATATT





1901
ATATGTTATA ACTTATACTG TCATATGTAA CATATACATA ATATTTTATA





1951
AATCAGTTTA ATATACATTA TGTTACATAT AATGTATGTT ATATATGATA





2001
TATTATATAT AATTATATTA TACATAATTG TTATATATAA TGCATACATT





2051
GTATTTGTTA CGTATTATAT GCAACATATG GGGATCCTCT AGAGTCGGAC





2101
CAGCGGCAGC AGCTGCCTGC CTTTTNNNNN NNNNNNNNNN NNNNNNNNNN





2151
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





2201
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





2251
ATATACATAC ATAACATATG TATAACTTAT ATGTTATATA TAAGTATATA





2301
ACATATATGT GTATGTGATG TATATAACAT ATCTGACATT AACATATAAC





2351
ATATGTTATA ATATGACATA TTATATATAT TACATATAAC GTATATCATG





2401
TATAATATAA TGTGTATATA TAATATATTA AAGTATATAA GTATAAATAC





2451
ATGTAATATT TAAATATATA TTATATATAG TATACATGTG GATACATACA





2501
ACTTCTACAT ATACCTAGTA TATATTCTAT ATATAAACAG TCCATGAATT





2551
ACAATGATTC AACTTATGAT TTTTCAAACT TTGTGATAAT GCCATAGCAA





2601
TATGCATTCA GTAGAAAGCA TACCTTCAAC ACCCATGCAA CCATTCTGTC





2651
ATTCACTTTC AGTACAATAT TCAATAAATT ATATGAGATA TTCAACAGTT





2701
TATTATAAAA TAGGCTTTGT GTTAGGTGAT TTTGCCCACA TGTAGGCTAA





2751
TGTAAGGGTT CAGAGCATGT TTAAGGTAGG ATAGGCTAAC CTATCATGTT





2801
CTGTAGGTTA GGTATAGTCG ATTTTTATTT TTATTTTTAT TTTTGAGACA





2851
GAGTCTTGCT CTGTCACCCA GACTGGAATG CACTGGTGCG ATCATAGCTC





2901
ACTGCAGCCT TGAACTCCTG GGCTCAAGTG ATCCTCCTAC CTCAGCCTCC





2951
TGAGTAGCTG GGACTACAGG TGTGTGCCAC CACACCTGGC TATTTTTTTT





3001
TTAATTTTTT TTTTTTTGTG GAGAGGAGGG TCTTGCCATG TTGCCCAGGT





3051
GGCCTTGAAC TCCTGGGCTC AAGGAATCCT CCCACCTTGG CCTCCCAAAA





3101
TCCTGGGATT ACAGGTGTGA GCCATCACGC CCGGCTACAG GGCATTTTTG





3151
ACTTATGACA TTTTCAGTTC ACAATGGATT TGTCAGGGCT GGGCATGATG





3201
GCTCACACCT GTCATCCCAG CACTTTGGGA GGCTGAGGCA GGTGGATCAC





3251
TTGAGGCCAG GAGTTTGAGA CCAGGCTGTC CAAATGGCAA AATCTTGTCT





3301
CTACTAAAAA TACAAAAATT AGCCAGGCGT GGTGTGACAA CTGTAGTTCC





3351
AGCTACTCGG GAGACTGAAG CGTGAGAATC ACTTGAACTT AGGAGATGGA





3401
AGTTACAGTG AGTCAAGATC ACACCACCGC ACTCCAGCCT GGATGACAGA





3451
GCAAGACTCT TGTCTCCAAA AAACAAAAAA CAGGCTGGGT GCATGGCTCA





3501
TGCCTGTAAT CCCAGCAGTT TGGGAAGCTG AGGCAGGTTT ATCACCTGAG





3551
GTCAGTAGTT CACGATCAGC TTGGCAAACA TGGAGAAAAC CCATCTCTAC





3601
TAAAAATACA AAAATTAGCT GGATGTGGTG GTGGGTACCT GTAGTCCCAG





3651
CTACTCGGGA GGCTGAGGCA GGAGAATGGA TTGAACCTGG GAGGCAGAGG





3701
TTGCAGTGAG CCAAGATCAC ACCATTGAAC TCCAGCCTGG GCAACAGAGT





3751
GAGACTCCAT CTCCAAAAAC AAAAGAAAGC AAAAACAAAA AAATAAAATA





3801
AAAAACCTGT GTTTATCAGG ACATAATACC ATCATGAGTC AAGAAGCATC





3851
TAAATGTACA TGGTAGTTAT ATAAAAATAG TTATATAGTT ATATACAATA





3901
GTTATATATA AACCAGTTTA ATATATGTTA AGTAGAGGTA TATGGTAGTT





3951
ATATAAAAAA TAGTTATATA ATAGTTATAG AGTTATATAA TTATATAAAA





4001
TAGTTATATA TAAACCAGTT TAATATATGT TAGGTAGAGG TATAATAATA





4051
TATATTGTAT ATACTATATA ATATAGTAAT GTATAAAATG CAAAACGATA





4101
TCATATATTT CTATATTAAG TTTATATTTA CAGATCTACA TTTTATATAT





4151
TTTATGTTAT ATACAATTGT GTTATACATA ATATAATTAG TATAGTACTG





4201
ACTTGGGGAA TTGAGCAGTA CCAACCCATA GGGATGTTTG AGGATGAAAA





4251
TATGTGATTA TGAATACAAA ATGCTGGGCC TGCTGCATAG GAAGTATTTA





4301
ATAAATGGTA GTTGTTACTA TAAAGTCGTT CCTACTATAG AGCTACTCAC





4351
AACCTGGGAC ATAGGGAAAG AGCCCGTTTC CCTCTAATCA CTCAATAGTG





4401
GGTGGCTAGG TAGGTGAGTC CACATCCTGT GGCCGGGAAC AGGTGCTGAG





4451
ACATGAAGAC CTTCTGACTG CATGTTGGAC CAGCCACAGT TTCAGACGGA





4501
CCAGCCAAAA AGGGCATTTT CCCCAAGCCA TTTAGCTCCC TTGAGTCTCA





4551
TAACAAATCT CCTAGACCCT GCTGGTCCAT AGGATCTAGA GAGGATGACT





4601
TGAACCTTCT GATCCCACCA TTTGAAAACG CCATGCCATG GGCACCAGTA





4651
GGAGGGCCAC TGCTACGTGC ACCAGTACAA GGGCCACTGC CATGGATTAC





4701
AGATTAACCC TAAGTATAGC TGTCGCACAC CTAGTACTTC AGGAGGCTTA





4751
TTCGGGGCCA TGCAGATCCC TGGCATTATT ATCCTAGGAT CCTACACCAA





4801
GCAAAGCAGG AGCTGCCCCT CCTCATAAAC CCATAAGCCC TCCTCTTGAG





4851
CAAAGCAGCT GGGAAGGCCA GAAGTTATTC AAGCTCCCCT CTGCCCCGGT





4901
TCCAAAGACA GACAGCTCAA GCCTACATGC AGCAAACCCT ATAAAAGTGT





4951
CACCTCTTGG CATTTCTGCC ATGGTAATGC TTTCTGCTTC CACTAATAAT





5001
CCTAGTAATT TGTTTATGGT GGGCATCTCT CTGATGAGAA CCACATTCTT





5051
TTTTTTTTTT TTTTTTTTTT TTGAGATAGA GTCTCACTCT GTTGCCCAGA





5101
CTGGAGTGCA GTGGCGCGAT CTCGGCTCAC TGTAACCTTT GGCTCCTAGG





5151
TTCAAGCAAT TCTCCTGCCT CAGCCTCCCA AGTAGCTGGG ACTGCAGGCA





5201
CGTACCACCA TGCCCAGCTA ATTTTTGTAT TTTTAGTTGA GACGGGGTTT





5251
CACCATGTTA GCCAGGATGG TCTCAATCTC TTGACCTCAT GATCCACCTG





5301
CCTTGGCCTC CCAAAGTGTT GGGATTACAG GCATGAGCCA CCATGCCTAG





5351
CCTGAGAGCC ACATTCTTGT TAACCACAAT TTTCTCAGAG TCTGCATTAG





5401
GGGTTGACAA AGAGTGGAAA GGAAGGACAA AAGGATGGAG AGGTGGATGG










Exon R3








5451
ACTAAGCATA TGTAGGTTCT TACCCAGGCC AGAGAAGGAT AGCTCAGCCA





5501

CGGCAGTGGA TGCCATCTGC ACACATCGCC CTGACCCTGA AGACCTCGGA






5551

CTGGACAGAG AGCGACTGTA CTGGGAGCTG AGCAATCTGA CAAATGGCAT






5601

CCAGGAGCTG GGCCCCTACA CCCTGGACCG GAACAGTCTC TATGTCAATG






5651

GTGAGCAGCT GTGATGTGGT TGGAGGCTCT TCCTCCTTGC TGAGCAGCCT






5701
GTAATCACTG GCTTGAGGTC ACACTCACTG TCAGGCAATT GAAAATTTGG





5751
TCCTGTGCTC TACATGGGAT GACTAATTTC CGGACTTCAT GGTATCTTTT





5801
TTTTTTTTTT TTTTTTTTTG AGATGGAGTC TCGCTCTGTC ACCAGGCTGA





5851
GGTGCAGTGG CATGATCTCA GCTCACTGCA ACCTCCGCCT CCCGGATTCA





5901
AGCAATTCTC CTGCCTCAGC CTCCTGAGTA GCTGGGACTA CAGGTGCATG





5951
CCACCACACC CAGCTAATTT TTGTATTTTT AGTAGAGACA GGGTTTCACC





6001
ATGTTGGTCA GGATGGTCTC AATCTCTTGA CCTTCTACTC CACCTTGCCT





6051
TGGCCTCCCA AAGTACTGGG ATTACAGGCT TGAGCCACCA CACCTGGCCA





6101
GGACTTCATG GTTTCTTCAT CATCATGGAA TGAATTCCAT CAGGGCATTC





6151
TTCCCTGATG TGAGGGCACT GATAGGAAAT CTTTAATGGT CCCTGCTGCA





6201
TGAAACTGCT TCCATTGCAC CAGGGTAGCC CTGACCCCTA TTTGGTCCCC





6251
CACATCTCCT TGTAACTTAC CCACACTCCT CCCTCCTTCT CTGTGCAGGT










Exon R4








6301

TTCACCCATC GAAGCTCTAT GCCCACCACC AGCAGTGAGT ATTCAACTCA






6351
TGTCCACATG CCCATGATCC TACACCAAGC AAAGCAGGAG CTGCCCCTCC





6401
TCATAAACCC ATAAGTCCTC CTCTTGAGCA AAGTAGCTGG GAAGGCAGAA





6451
GTTATTCAAG CTCCCCTCTG CCCCAGTTTC AAAGACAGAC TCAGCTCAAG





6501
CCCACATGCA GCAAACCCTA TAAAAGTCTC ACCTCTTGGC ATTTCTGCCA





6551
TGGTAATGCT TTCTGCTCTC ACTAATGAGG ACTTCTCCTC AGCTCCTGGG










Exon R5








6601

ACCTCCACAG TGGATGTGGG AACCTCAGGG ACTCCATCCT CCAGCCCCAG






6651

CCCCACGAGT AAGTACCAGT CAATGGCATC TCTATTAGAG CATGCTATCT






6701
CTGTCATTTT TACTCAGATG AAGATGGAAA ATCATAGCAA ATCTACTGAT





6751
AGTGAGTGGA CCAACGAAAT TTGTTGGCCA CCTAGTGTGT ACCAGATCCT





6801
AGAGATACAG GAGGGAAAAC AAAACCAATA CAAAATTTCT GCTCTCAGTG





6851
AGCTTGTATT CTTGTCATGA TGATGATGTT GGTGGTGGTG CTGTTGATGA





6901
CGATGATGAT GATGATGATG ATGATGATGC TGGTGATACT GTTGATGGTG





6951
ATAGTGATGT TGATGACAAT GATGATGATG ATGATGTTGA AGAAAATGAT





7001
GCTGGTGATG GTGGTGGGGG TTATTATGGT AATAATGATA TGTTGAGTGT





7051
GACGATGATG GTGGTGGTGT TGATGATGAT GATGATTATT ATGCTAGTGA





7101
CATTGATGAT GGTAATGGTG ATATCAACGA CAGTGACAAT GATGGTGATG





7151
AGGATGATGT CGGTGATGGT GGTGGGGTTA TGATGGTAAT GATATGTTGA





7201
ATGTGATGAT GGTGATGATG ATATTTGTGG TTCATGATGG GGATTGTCAT





7251
GGTGGTGCTG GTGGTACTTG TGATGACAAT AATGATAATA ATGATGACAA





7301
TGATAGTGAT GATGGTGATG GTGATAATAA AGATAACAGA TATCACCTTA





7351
CAATATTGAG CACTAAATAT GTACCAAGAG CTATGCTCAG TATCTAACTA





7401
CTATTATATA ATCTACTTTA GAAAATGAAT TGTATCATAG ATAAGAAAGG





7451
CGTGGAAAAT ATTTATTATG TCACTCAATT TAATTGCTGC ATATGGTTAT





7501
TACAAAGTGC TATTCTCTCT ACTTTGAACA TAATGTTTAT TTCACACTCC










Exon R1








7551
CACTATAGCT GCTGGCCCTC TCCTGATGCC GTTCACCCTC AACTTCACCA





7601

TCACCAACCT GCAGTACGAG GAGGACATGC GTCGCACTGG CTCCAGGAAG






7651

TTCAACACCA TGGAGAGTGT CCTGCAGGGT CTGGTTAGTG TCCTGCCCTC






7701
CACACTCTGC CCTGCTCATG ATACCCAGTC CCTCTTACAT CATCCATGCC





7751
AGGGCAATGG AAGAATATCA AACCCAACTC ACTTTTGCCC CAAGAGATGC





7801
AAGCCTCAGC CAGGAGCGGT GGCTCACGCC TGTAATACCA GCATTTGGGA





7851
GGCCAAGGCG GGTGGATCAC CTGAGGTCAG GAGTTTGTGA CCAGCCTGGC





7901
CAACATAGTG AAACCTCATC CCTACTAAAA TACAAAAATT AGCCAAGCAT





7951
GGTGGTGCAT GCCTGTAATC CCAGCTACTT GGGAGGGTGA GGCAAGAGAA





8001
TCACTTGAAT CAAGGAGGCA GAGGTTGCAG TGAGTCAAGA TCATGCCACT





8051
TTACTCCAGC CTAGGCAAAA AAGCGAAACT CCATCTCACA AAAAAAAGAA





8101
AAAAAGAGAG AGATGCAAGC CTCCCCCACC AAGGCCAGCC CTGCCCACCT





8151
CACTTCTGCC TGGCTCTTAC ATAAAACTTA GCCCTCCTAC TCACTGCCCT










Exon R2








8201
CTCCCTCCTC CACAGCTCAA GCCCTTGTTC AAGAACACCA GTGTTGGCCC





8251

TCTGTACTCT GGCTGCAGAT TGACCTTGCT CAGGTGAGAA CTTAGAATTT






8301
CCAGCCTGGC TGCCCCACTT GTACTCACTC CAAAAGACTT TGCACTGCTT





8351
CCTTGCTGCA CTTCCTAGGG ATATCCTCAC CAAAGGTGGA ATTCAGGAGT





8401
CACAGGCTTC AGGATCAGTG TGTTTCCTGA CAGTAACACC CCTACACTCC





8451
ACCTCAACAG AGAGAATCTG CATGGCCCAT CATCAGGATT GAGCCTCTCC





8501
CTTTATCATC CCTCTGAATT CCCTCCATTC CCTGTGCCTC CCTTTCCTTT





8551
ACATGTTAAA TTCTGTCCCC AGGATTTCTT TCAGGACAAT CATGCCTTAT





8601
CCACGTGATT TCATCCTCAT TTCGAGCTCT TCACTGGGCT CAAGTCCGGC





8651
TCCCCGTCCC GTCCATGAAA GTGTCAGTTT CATCTTGTCA CTGTATCCGT





8701
GACTCCACTC ACAGTCCTCA GCAAGCCAAT AGTCCATGCA CTAAGAGTCG





8751
ATGTGGCTTC TCACCTCTTT CCCAGGTTTC TCATTTCTCT GGTCCTTGCT





8801
GTCCTTCCCT CAGCAATCGC AAGACCCTTC CTAGATAAAC TTTTCATTGT










Exon R3








8851
GATTTTTCCC ACTGACCCTC CCCAGGCCCG AGAAAGATGG GGCAGCCACT





8901

GGAGTGGATG CCATCTGCAC CCACCGCCTT GACCCCAAAA GCCCTGGACT






8951

CAACAGGGAG CAGCTGTACT GGGAGCTAAG CAAACTGACC AATGACATTG






9001

AAGAGCTGGG CCCCTACACC CTGGACAGGA ACAGTCTCTA TGTCAATGGT






9051
GAGTGGCTGT GATGTGGTTG AAATCTCTTC CCCCTTGCTG GGCAGCCTCT





9101
AATCTCTAAC TAGAGATCAC ACTCCCTGCC TGGCCTTTGA AAATTCTGTC





9151
ATGTGCTCTA CATGGGATGA CTAAGGTCTG GACTTCATGG TTTCCTTACC





9201
ATCATGGACT GTGTTCCCTC AGGGCATTCT TTCCTGATGT GAGGATGCTG





9251
ATAGAAAATC TTCAATTGTC CCTGTACCAT GAAACTCGGT TCATTGCACC





9301
AGGGTAGCAT TGACCTCCAT TTGGTCCCCC ACCTCTCCTT GTCTCTTACC










Exon R4








9351
CACTCTCCTC CCTCCTTCTC TATGCAGGTT TCACCCATCA GAGCTCTGTG





9401

TCCACCACCA GCAGTGAGTA TTCAACTCAT ATCCACATGC CTCGGTTCCT






9451
ACACCAAGAG GAGCAGGAGC TGGCCCCTCC TCATAAACCC ATTAAGTCCT





9501
CTTCATAAGC AAAGGATTTA GGAGGGCAGA AGTTATTTAA GTGTCCCTCT





9551
GCCCAGCTCA AGAGACCGAC CCAGCTCAAG CTACACATGC AACAAACCCC





9601
ATAAATAGTC TCCCCTCTTG CCATTTCTGC CAAGAGAGTG CTTTATGCTT










Exon R5








9651
TCACTGATGA GAACTTTTCC TCAGCTCCTG GGACCTCCAC AGTGGATCTC





9701

AGAACCTCAG GGACTCCATC CTCCCTCTCC AGCCCCACAA GTAAGTATCA






9751
GTCAATGACA TCTCTATGAG AGCATACCTG ATTAGTGTAA ACATCTCTGT





9801
CATTTTCACT CAAATAAAGA TGGAAAATCA TAGTAAATCT AGTGATACTG





9851
AGTGGACAAA TTTGTTTGTT TGTTTTTTCT CATCCTTTTC ACTTTTTTTA





9901
TTATACTTTA AGTTTTAGGG TACATGTGCA CAATGTGCAG TTTAGTTACA





9951
CATGTATACA TGTGCCATGC TGGTGTGCTG CACCCATTTG CTCGTCATTT





10001
AGCATTAAGT ATATGTCCTA TGCGATCCAA GCCCACGCGC CGCACCACGT





10051
GCAACAGTTT CACAGATTGG ATGGTCCGAT ANNNNNNNNN NNNNNNNNNN





10101
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





10151
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R1








10201

CTTCACCATC ACCAACCTGC AGTATGAGGA GGACATGCAT CGCCCTGGAT






10251

CTAGGAAGTT CAACACCACA GAGAGGGTCC TGCAGGGTCT GGTTAGCACC






10301
CTGCCCTCTT CACTCTCCCC CGCCCTGGAT GCCGAGCCCC TCATACAACA





10351
TTCATGCCAG GGCAATGGAA GAATATCGCA CCAACCTTGC CCTCATCCCC





10401
AGAGATGCAA GCCTCACCCA CTGAGGCCAG CCACTCTCAT GGGTGTCTGC





10451
CCCACCCACC TCACTTTTGT CCCCACACAG GGACCTTAGC CCTCCTACTT










Exon R2








10501
ACCTCTCTCT CCCTCCCCCA CAGCTTAGTC CCATATTCAA GAACACCAGT





10551

GTTGGCCCTC TGTACTCTGG CTGCAGACTG ACCTCTCTCA GGTGAGACCT






10601
TAGAAGATCC AGCCTGGCTG CCCCAGTTGT TCCCACTCCA GTAGATTTTG





10651
CTCTGCTTCC TTGCTGCACC TCCTAGGGAT ATCCTCACCA AAAGGGGAAT





10701
TCAGGAGTCA CTGGCTTCTG GACCAATGTG TTTCCTGATA GTAACACTCC





10751
CACACCTCAC CTCAACAGGG AGAATCTGCA TGGTCCATCA TCAGGATTGA





10801
GCCTCTATCC TGATCATCCC TCAGAATTCC CTGCCCCTCC CTTTCATTTA





10851
GGTGTTAAAT TCTGTCCCCA GAATTTCTCT CAAGACAATC ATGCCTCATC





10901
CAAGTGCTTT CATCCCTGTT TCTAGCTCTT CACTGGTCTC AAGTCTGGGC





10951
TCTCCTGTCC CCATGCTATG AGAATGCAGG TTTCACCTTG CACTTTTATA





11001
AGCATGGTTG TATCTGTGAC TCTGTGCACA GTCCCAAGCA AGCCAGTAGT





11051
CCATGCACTC AGAGAATCTA AGTGTAGCTT CTCACCTCTT TCCCAGGTTT





11101
CTCATTTCCT CTGGTTCTTT ACTGTCTTTC CATCAGCAGT CTCAGGACAC










Exon R3








11151
AACCTAAGTA ATCTTTTCAT AGTCATTCTC CCCACCTACC TTCCCCAGGT





11201

CTGAGAAGGA TGGAGCAGCC ACTGGAGTGG ATGCCATCTG CATCCATCAT






11251

CTTGACCCCA AAAGCCCTGG ACTCAACAGA GAGCGGCTGT ACTGGGAGCT






11301

GAGCCGACTG ACCAATGGCA TCAAAGAGCT GGGCCCCTAC ACCCTGGACA






11351

GGAACAGTCT CTATGTCAAT GGTGAGCAGC TGTGATGTGG TTGGAGTCTT






11401
TTCCTTCTAG AGTCTGGAAA GAATCTAATC TGTGGCTTGA AGTCACACTC





11451
CCTGCCTGGC CATTGAATAT TCTGTCATGT GGTGTAGATG GGATGACAAA





11501
GTTCTGGACT TCACAGTTTC TTCATTGTCG TGAACTGTGT TCCCTCAGGG





11551
CACTCTTCCC TGTTGTGAGG ATACTGATAG GAATTCTTTA ATGGCCCCAG





11601
TCCCATGAAA CTCATTGTCC CATGAAACTC ATTTAATTGC ATTGGGATTG





11651
CCATGACCTT ATTGTGTCCC TCGTATCTCC TTAACGCTTA CCAAGTCTCC










Exon R4








11701
TCCCTCCTTC TCTATGCAGG TTTCACCCAT CGGACCTCTG TGCCCACCAC





11751

CAGCAGTGAG TATTCAACTC ATGTCCACAT GCCCCTGATC CTACATTAAG






11801
TGGAGCAGGA GCTGGCCCCT CCTCTTAAAC CCATAAGTCC TCCTCTTGAG





11851
CAAAGGAGCT GGGAAGGCAG AAGTTATTGA AGCTCCCTTC CACCTAGCTC





11901
CAAAGACAGG CCCAGCTCAT GCCCGTATGC AGCAGACCTC ATAATAGTCT





11951
ACCTTCTTGC CATTTCTGCC ATGAGATTAT TTTCTGCTTT CACTGATGAG










Exon R5








12001
CACTTTTTCT CAGCTCCTGG GACCTCCACA GTGGACNNNN NNNNNNNNNN





12051
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





12101
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R1








12151
ATTTTCAATT CCCACTACAG CTGCTGGCCC TCTCCTGGTG CTGTTCACCC





12201

TCAACTTCAC CATCACCAAC CTGAAGTATG AGGAGGACAT GCATCGCCCT






12251

GGCTCCAGGA AGTTCAACAC CACTGAGAGG GTCCTGCAGA CTCTGGTTAG






12301
TGCCCTTCCC TCCTCACTCT GCCCAGCCCC AGATATCCAG TCCCTTCTAC





12351
ATCATCCATG CCAGGGTGAT GAAAGAAGAT AGCAACAACT TCCCCCCTTC





12401
CCCCCAAGAG ATGCAAGCCC CACCCACAGA GACCAGTCCT GCTTATTGGT





12451
GCCTGCTCCA CCCACCTCAC ATCTGCCCCG ACACACACAC ACCTTAGCCC










Exon R2








12501
CACTACTCAC CTCCCTCTCC CTCCTCTACA GCTTGGTCCT ATGTTCAAGA





12551

ACACCAGTGT TGGCCTTCTG TACTCTGGCT GCAGACTGAC CTTGCTCAGG






12601
TGAGACTTTA GAAGAGCCAG CCTGGGTGCC CAAACTTGTT CCCACTCTAA





12651
AAGACTTTGC ACTGCTTCCT TGCTGCACTT CCTAGGTATA TCTTCACCAC





12701
AAGGGGAATT CAGGAGTCAT TGGCTTGAGA ACCAGTTGTT TCCTGATAGT





12751
AACACCCCCA TGCCCCAACT CAACATGCAA AATCTTCATG GTTCATCATC





12801
AGGATTGAGA CACTACCCTG ATTACCCATC TGAATTCCCT CCTTTCCCTG





12851
ACCCCTCCCT TTCATTTAGG TGTTAAATTC TGTCCCCAGG ATTTCTCTCA





12901
AGATAACCAT GCCTCATCCA CATACATGCA TCCGCCTTTC AAGCTCATCA





12951
CTAGTCTGAA GCTCTGGGTT CTCCTGTTCC CATGCCATGA GAATGCAGGT





13001
TTCACCTTGC ACTTTTATAA AAATTATTAT ATCCATGACT CTGCTTGCAG





13051
TCCCAGACCA AGATAGTGGT CTATGTACTC AGATAATCTA AGTGCAGATT





13101
CTCACCTCTT TCCCAGATTT CTCATTTCCT CTGGTTCCTT GATATGTTTC





13151
CCTCAGCAAT CTCAAGACAA GTCCTAGGCA ATCTTTTCAT TGTCATTCCC










Exon R3








13201
CCTCCTACCT TCCTCAGGTC CGAGAAGGAT GGAGCAGCCA CTGGAGTGGA





13251

TGCCATCTGC ACCCACCGTC TTGACCCCAA AAGCCCTGGA GTGGACAGGG






13301

AGCAGCTATA CTGGGAGCTG AGCCAGCTGA CCAATGGCAT CAAAGAGCTG






13351

GGCCCCTACA CCCTGGACAG GAACAGTCTC TATGTCAATG GTGAGCAGCT






13401
GTGATATGGT AGGGGTCTCT TCCTCCTGGC TGTGCAACCA TCTAATCTCT





13451
GGCTTGGGGG CACACTCCCT GCCTGGCCAT TGAAAATTCT GTCACGTGCT





13501
CTACATGGGA TGACTAAGTT CTGGACTTCA TGGTTTCTTT GTTATCATGA





13551
GAGGCATTCC CTCTGGGCAC TCTTCCCTGT TGTGAGGATG CTGATAGGAA





13601
ATCTTTAATG ACCCCTGTCC CATGAAACTC ATTTAATTGC ACCAGGGTAG





13651
TCCTGAACTC TATCGCGTCC CCCACATCTC CTTAACCCTT ACCCAGTCTC










Exon R4








13701
CTCCCTCCTT CTCTATGCAG GTTTCACCCA TTGGATCCCT GTGCCCACCA





13751

GCAGCAGTGA GTATTCAACT CATGTCCATG ATGCCCCTGA TCCTACATCA






13801
AGTGGAGCAA GAGCTGGCCC CTCCTCTTTA ACCCATAAGT CCTCCTCTTG





13851
AGCAAATGAG CTGGGAAGGC AGAAGTTACT CAAGCTCCCC TCTGCCCCAG





13901
CTCCAAAGAC AGACCCAGCT CAAGCCCACA TGCAGCAGAC CTCATAATAG





13951
TCTATCTTCT TGCCATTTCT GCCATGAGAG TGCTTTCTGC TTTCACTGAT










Exon R5








14001
GAGGACTTTT TTCAGCTCCT GGGACCTCCA CAGTGGACCT TGGGTCAGGG





14051

ACTCCATCCT CCCTCCCCAG CCCCACAAGT AAGTACCAGC CAATGGTATC






14101
TGTATTAGAT CATGCCTGAT GAATGCAAAC ATCTGTGCCA TTTTCAGTCA





14151
AATGAAAATG GAAAATCATA ATAAATCTAG TGATACTGAG TGAACCAAAA





14201
AAAATGTATT GGCCACCTAC AGTGTACCAG ACCCTAGGGA TATAGCAAGG





14251
AAAATAGAAC CAATAAAAAC ATCTCTGCCC TCAGTGAGCT TGTGTTCATG





14301
TGATGATATG ATGGTGGTGG TGGTGGTAAT AGTAATAATG ACATATTCAG





14351
TTTGATGATA ATTTATGATT ATGGTGTTGC TGTTGATGAT GGTGGTGGTG





14401
ATGTTACTGA CAATGATGGT GACGGATCTT TGAGGATATT GTCCGTGATG





14451
GTCGTGAAGA TTATGATGAT AATGATGATG TGTTAAGTGT GATGATGATG





14501
ATGATCTGTG GTGATGCTGT TTAGGATGCT GTTCCGTGGT ACCGATGATA





14551
TTGATGTTGG TCGTGGTTAT GTTGTATGAC AATGACAATG ATGGTGATGA





14601
GGATAATCGC CAGTGATGGT GTGGGTTTAT GATGATGATG ATGTGTTGAA





14651
TGTGGTGATG ATAATGTTCG TGGTGGTCGT GATGGGCATT ACTATGGCAG





14701
TGATGGTCAT AATAATGATG GTGATGGTGA CAATGATAGC AAGGATGATG





14751
ATGGCAATAA AGATAGTACA TAACATCAGA CAATATTGAG CTCTGAATAT





14801
GCACCACGAG GAGTGCTCAG CATCTAAATA CTATTATATA ATATATTTTT





14851
GTAAAAATAA ATTGTATTGT TTTAGGCAAG GGAAGCATGG TAAATATTTT





14901
GTCACTCAAT TTAAATTCTG CATATGTTTA AAGATAAGTC TATTGCAAAC





14951
TCCTATTTTC TCTACTTTGG ACATAGTGTT TGTTTCCCAC CTCCACTACA










Exon R1








15001

GCTGCTGGCC CTCTCCTGGT GCCATTCACC CTCAACTTCA CCATCACCAA






15051

CCTGCAGTAC GAGGAGGACA TGCATCACCC AGGCTCCAGG AAGTTCAACA






15101

CCACGGAGCG GGTCCTGCAG GGTCTGGTTA GTGCTCCACC CTCCTCACTC






15151
CGCCCCACCC CAGAGAGTCA GTACCTCCTA CATCATCCAT GCCAGGTGAT





15201
GGAACAAGAT CATACCCACC TCACCCTTGC CCCAAGAGAT GCAAGCCATG





15251
CCCATTGAAA CCAGCCCCAC TCACTGATGC CTGTTACTGC CCCACCTGAC





15301
TTCTGCCCTA CACACCCACA CACGCAACTT AGCCCTCCTA CTCATCTCCT










Exon R2








15351
TCTCCCTCCT CCACAGCTTG GTCCCATGTT CAAGAACACC AGTGTCGGCC





15401

TTCTGTACTC TGGCTGCAGA CTGACCTTGC TCAGGTGAGA CCTTAGAAGA






15451
TCAAGCTTGG CTGCCCCACT TGTTNNNNNN NNNNNNNNNN NNNNNNNNNN





15501
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





15551
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R1








15601
NGTGTTAGTC TACTTTTGAA CACTGTTTAT TTCCCATCTT CACTATAGCC





15651

GCCAGCCCTC TCCTGGTGCT ATTCACAATT AACTTCACCA TCACTAACCT






15701

GCGGTATGAG GAGAACATGC ATCAGCCTGG CTCTAGAAAG TTTAACACCA






15751

CGGAGAGAGT CCTTCAGGGT CTGGTAAGAG CCCCACATAC CTCATTCTAC






15801
CGCCACTCAC CATGTTTAGT CCTGCCCACC TCACCTATTG CAGAGCATGG





15851
AAGATCTCAT CTACCTCATC TTGCCCCCAG ATATGCATAC CCCAACCACT





15901
GATGCCAGCC CCACCAACTG TTGCCAGCCC TGCCCACCTC CCTTCTACCA





15951
CACCCCTATG ACTTCAGTCC TCCCACTCAC CTCCCTCTCC CTCCTCCACA










Exon R2








16001
GCTCAGGCCT GTGTTCAAGA ACACCAGTGT TGGCCCTCTG TACTCTGGCT





16051

GCAGACTGAC CTTGCTCAGG TGAGAACTGA GAACAGCCAG TCTGACTGAT






16101
CTGAGCAGTT TGACCTGCTT CCCTTCTGCA CTCCCTGGAG ATGTCCGCAG





16151
CCAGGTGGAA TCCAGGAGGC AGTGGCTCTA AGACCAATGT GCTTCCTGTT





16201
CCCACCACCT CCCACCTCAA CTGAGAGATG CAGAGCCCAT CAGCAGGACT





16251
GAGCTTCTAC CTTGGTCATC CCTCTGAATT CCCTCCTTTC CCCTACCTGC





16301
CTTTCCACAA GTGGTTCAAT TCTGTTCCCA GGATTTCTCC CAAGAAAAAC





16351
ATGCCTCGTC CACTTGCTTT CATCCCCAAA CCTAGCTCTT CACCTGTCTC





16401
AAGTATGAGT TCTCCTTACC CCATGCTACA AGAATGCAGT TTCCACTTTG





16451
CAATTTTATA AAAATCCTTG CATCCATGAT TCTGCTCATA GTTGCTAAGA





16501
GTCAGTGCAC TCAGAGAATG GAAGTATGGC TTCTCACTTC TCTACCAGGC





16551
TTCTCATTTC CTCTGGCCCC CTCCTGTCCT GCCCTGTGGG ATCTCAGAAC





16601
CCCTCCCTAG GCAATCCGTG TATTGTCTTT CCCCAATCTT GCCCTCCCCA










Exon R3








16651
GGCCCAAGAA GGATGGGGCA GCCACCAAAG TGGATGCCAT CTGCACTTAC





16701

CGCCCTGATC CCAAAAGCCC TGGACTGGAC AGAGAGCAGC TATACTGGGA






16751

GCTGAGCCAG CTGACCCACA GCATCACTGA GCTGGGCCCC TACACACTGG






16801

ACAGGGACAG TCTCTATGTC AATGGTGAGT AGTTGTGATG TGGTTGGAGT






16851
CTCTTCCTCC TTGCTGGGCA GCCTCTACTC TCTGCCTTGA GGTCACGCTC





16901
CCTGCCTGGC TATTGAATGC TCATCCATGT TGTCTGTATG TGATGGCTGA





16951
GGTTGGAACT TCATGGTTTC TATTTCATCT TGGACTGAGT TCATCCTCAG





17001
GATCTGCTTT CTGGATCTGA GGGTGCTGAT AGAGAATCTT CAATGGTTCG





17051
TGTTCTGGGA AATTCCTTCC ATTGCACCAG GGTACCCTGA CCCCTATATA





17101
GTTCCCCACC ACTCCCTTAA CCCTTACCCA CCCTCTTCCC TCCCTCTCTA










Exon R4








17151
TGCAGGTTTC ACACAGCGGA GCTCTGTGCC CACCACTAGC AGTGAGTATC





17201
CACTGATTTC CAGTGCTCCT GATCCTACAT CATGCAGGGC AAGAACTGAC





17251
CCCTCCTCAC ATGCCCCTAT GTCCTCTATG AGCAAAGGAG CTGGGACAGC





17301
ACAAGTTACT CCCTTTCCCT TCTGGCCCAA GTCTCTTCAG AGAGAGACCC





17351
AGCTCAAGCC CCACATGCAG CAAGGTCCAT AAATACTCCT ACCTGCTGGC





17401
ATTTCTGCCA TGAGAGGGTT CAACACTTTC ACTAATGAGG CCTTCTCCTC










Exon R5








17451
AGTTCCTGGG ACCCCCACAG TGGACCTGGG AACATCTGGG ACTCCAGTTT





17501

CTAAACCTGG TCCCTCGGGT AAGTACAAAT CAATCGCATC TCTGTTAGAG






17551
CATGCCTGAT GACTGTCAAC ATCTCTGCCA TTTTCACTTA AATAAAGATA





17601
AAAAATCCTA GTGAATCTAC GGATGAGGAG TCATCCAGCA AACTTAATTG





17651
AGTGCCTAGT TTCTGCAGGG CTCTAGGGAT AAGAAAGGGG ACACAAAACA





17701
GTTAAAAATA TCTGCTGCAA GAAAGCTTAT TTTATTGTGA GGGTGATGGG





17751
AGTTGGTGGT GGTGAAGTTA CTGGAGATGA TGACAATAAG AATGGTGATG





17801
CTAGTGATGA TGATGGTGAT AAGGATGATA ATTATGAAGA TGGTGGTGGT





17851
GATGATGATG ATGGTNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





17901
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





17951
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18001
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18051
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18101
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18151
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18201
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18251
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18301
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18351
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18401
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18451
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R1








18501
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NGCTGCCAGC CCTCTCCTGG





18551

TGCTATTCAC TCTCAACTTC ACCATCACCA ACCTGCGGTA TGAGGAGAAC






18601

ATGCAGCACC CTGGCTCCAG GAAGTTCAAC ACCACGGAGA GGGTCCTTCA






18651

GGGCCTGNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN






18701
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18751
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





18801
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R2








18851
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNCTC AGGTCCCTGT





18901

TCAAGAGCAC CAGTGTTGGC CCTCTGTACT CTGGCTGCAG ACTGACTTTG






18951

CTCAGGNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNAGAAT






19001
TCAGTCGACC TACCGGCTTT GATGATTGCT CAGTTGAACT TAGAAATGCA





19051
CTGTCTGCCC AATGGTCCAG TCTCATGAGT GTGACTCTTT TCTGCCTCTC





19101
TTGGGTATCT GATCAAGATG GACTCAGGAA AAGTGCTCCA GATAACTGTC





19151
TCCAATATAA CACTGCCCCT GCCATCACAC CCAAATGACT GGAAGTTTCA





19201
CAGGGTCATC AGCAGGGATT GGACTTCCAC CCCGGCCATC CCTCTGAATT





19251
TTCCCTCTTT TCTCCCCACC TCCCTTGCCC TTAGGTGTTA AAATTCTCTA





19301
ACTAAGATTT CTCTCAAGAC AAATGTGCCT CATTCACTTG TTTAATTCCC





19351
AATTCCAGCT TGTCACCTGT CTCAAGTCTA GGCTGTCCTG TCCCCATGCC





19401
ATGAGAATGC AAGAACCACA CTGAAATGTT AGAAAAATTC TTTTATCCAC





19451
AAGTATGCTC ACCGTCCCAA GCTGGACAGT AGTCAGTGCA CTCAGAGAAT





19501
CTAAGTGTGG CTTCTCATCT GTGTACCAGG CTTCTCATTT CCTGTGGGCC





19551
CTTCTTGTCC TTCCCTCCGC AATCTTGGGA CTCCTCCCTA GACAAAACTT










Exon R3








19601
TATTATTATT CCCCTCACCT GCCCTCTCCA GGCCTGAAAA GGATGGGACA





19651

GCCACTGGAG TGGATGCCAT CTGCACCCAC CACCCTGACC CCAAAAGCCC






19701

TAGGCTGGAC AGAGAGCAGC TGTATTGGGA GCTGAGCCAG CTGACCCACA






19751

ATATCACTGA GCTGGGCCCC TATGCCCTGG ACAACGACAG CCTCTTTGTC






19801

AATGGTGAGC AATTGTGATG TGGTTGGAGT TTCTTCTTCC TTGCTGAGCA






19851
GGCCTCTACT CTCTGTCTTG AGGTCACTCT CCCTGCCTGG CCACTGGTCT





19901
TGGCCATGTT GTCTGTATTT GATGATTGAT ATGAACTTCA CCGTTTCTTC





19951
TTCATCTTGT ACTGGAGACC TTCATCCTCA GGACCTTCTT CCCTGATCTG





20001
AGTGTACTTG TATAGAATCC TCAAAGCCCA TGTTCCCTGA AACTCCTTCA





20051
ATTGCACCAT GGTAGCACTG ACCCCTTTTG GTCCCCCACC TTNNNNNNNN










Exon R4








20101
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN TTCACTCATC





20151

GGAGCTCTGT GTCCACCACC AGCACTNNNN NNNNNNNNNN NNNNNNNNNN






20201
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





20251
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





20301
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN










Exon R5








20351
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNCCTG GGACCCCCAC





20401

AGTGTATCTG GGAGCATCTA AGACTCCAGC CTCGATATTT GGCCCTTCAN






20451
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNGACTCCA GCCTCGATAT





20501
TTGGCCCTTC AGGTAAGTAC CAGTCAATGG CACCTCTATT AGAGTATGCA





20551
TGATGAGTGT CAACATCTCT GTCCTTTTCA CTCAAATAAG ATTAAAAATC





20601
ATAGCAAATT GTACGTGATG ATGAGTCACC CAACAAACTT CTTTGAGTAC





20651
CCACTCTCTG CCAGGCCCTA GAGATAAGGC AGGGAACACA AAAGAGGTAA





20701
AAATCTCTGC CCTCAGAGAG CTTCTTTTAT TTTGAGGATG ATGTGGGATA





20751
GTGGTGATGA TGATGTTGCT GGAGATGATT ACAATAATGA TGGTGATGCT





20801
TATGACCATG ATGTGATGAT GATGGTGATT ATGAAGATGA TGATGATGAT





20851
ATTGATGATG GTAGTGGTTT TGACAGTAAT GATGATGTGA TGATGATGAT





20901
GATAGTGGTG GTGGTGATTA TGGGAAGGAT GACAGTGGTG GTGGTGATGG





20951
TGGTGGTTGT GGTGGTGATT GACAATGTGG TGGTGATATT GACAATGAGG





21001
ATGATGATGA TAGTGGTGGT GGTTATGATG GTTAAGGATG ATGTGATGAT





21051
GGTGTTGGTG ATCACGGTAC TAGTGGTGGT GATGTGGACC GTCATGGTTG





21101
TGGTTGTGGT GGTGATGGTG GTGATCATGA TGATAATGAG GATGATGGTG





21151
GTGATTGTCA TGATGGTAAG GATGAAACAG TGATGGTGTT GGTGACCATG





21201
TTCCTGGTGG TGATGGTGCA GGTGATGATG TGGATGATGA TGGTGATGGT





21251
GGTGGAGATG ATAGGGATTA TGAATATGGT TCGGGTCTCT GACTGGTGGT





21301
GGTGATGACA ATAATGAAAA TGATGGTCAC AGTGTTGGTG ATGATGATGG





21351
TGGTGATAAC AAAGGTAATA GATAGTGTCT AGTATTATGG AACACAGAAC





21401
ATCACCAAAG GTTATGCTCA GCATCTAACT ATTATTATTT AGCATGCTCT





21451
ATGAAAAACT TTGATCGTTA TAGTCAAGGG AGGCATGAAA ACCTTCTATT





21501
TTATCACTCT CTTTAAATCT GGTTGCATAT GTTTAGAAAT AAATCTATTA





21551
CAAACTCTTA AATGTTCTCT ACTTTTGAAC ATAGTGTTTA TTTCCCACCT










Exon R1








21601
CCACTACAGC TGCCAGCCAT CTCCTGATAC TATTCACCCT CAACTTCACC





21651

ATCACTAACC TGCGGTATGA GGAGAACATG TGGCCTGGCT CCAGGAAGTT






21701

CAACACTACA GAGAGGGTCC TTCAGGGCCT GGTGAGAGCC CTGCCCACCT






21751
CACTCTGCCC TGCCCACCTT GTCTTGTTCC ACCTACGTCA CCCATTCCAA





21801
GGCATGGAAG AAGATCTCAC CCACCTCCCC TCACCTGAGA GATAGCCCCG





21851
CCCCCTGATT ACAGCCCCTT CCACCTTACA TCTTCCTCAC TTCTATGTCC










Exon R2








21901
TCAGCCATCT TACTCACCTC CCTCTTCCTC CTCCACAGGC TAAGGCCCTT





21951

GTTCAAGAAC ACCAGTGTTG GCCCTCTGTA CTCTGGCTGC AGGCTGACCT






22001

TGCTCAGGTG AGAACTGAGA ATAACCAGTC TGGCTACCCC AAGTGTTCCC






22051
AGGCCCAAGG AGTTTCATCA GCTTTCTTCC TTCCCTCCCT ATGGAAGTCC





22101
TCAGCACAAG TGGAATTCAG GCGTTGGTGG CTCCAGGATG AACATATCTG





22151
CTGATCCTAC CACCTCCCCC ATCAATCGAG AGAATTTGCA GGGCCCATCA





22201
GCCAGATCAG GCTTCTACTT TGGTCATCCT TCTGAATTTC TTACTTCTCC





22251
CTACCTCCCT CTCCTTCAGG TGTTAAATTC TCTTCCAAGG TTTCTCTCAA





22301
GATAAACATC CCCCATCCAC TTGCTTTCAT CCCCAATTCC AGCTCTTAAT





22351
ATTTCTCAAG TCTGGGCTCT CCTGTCCCCA TACCATGAGA ATGCAATTTT





22401
ATAAAATTCT TGTATTCCTG ACTCTACTCA CATTCCCAGG CTGCCTGGAA





22451
GTTGGTGCAT TCAGAGAATC TTAGTATGGC TTCTCACCTG TCTACCAGGA





22501
TTCTCATTTC CTCTGTCCCC TTCCTGTCCT GCCCCCAGGA ATCTCAGGAT





22551
GCCTCCCCAT AGGCAATCTA TTTAATGTCA TCCCCCTTAT CTGCCCTCCC










Exon R3








22601
TAGGCCAGAG AAAGATGGGG AAGCCACCGG AGTGGATGCC ATCTGCACCC





22651

ACCGCCCTGA CCCCACAGGC CCTGGGCTGG ACAGAGAGCA GCTGTATTTG






22701

GAGCTGAGCC AGCTGACCCA CAGCATCACT GAGCTGGGCC CCTACACACT






22751

GGACAGGGAC AGTCTCTATG TCAATGGTGA GCGGCTGTGA TGTGGTTGGA






22801
GATTCTTCCT CTTTGCTGGA CAGCTTCTTA CTCTCTGACT TGAGGTCACA





22851
CTCCCTGACT GGCCATTGAC GTCTTGGCTA TGTTGTCTGT ATGTGATGAC





22901
TGATGTCTGA ACTTCATAGT TTCTTCATCT TGGACTGAGT TCATCCTCAG





22951
TACCTTCTTC CCTGATCTGA GGGTACTGAT AGAGAATCTT CAAAGGCCCC





23001
TGTTCCTTGA AACTTCTTCC ATTCCACTAG GGTATCTGTG ACCCCTATTT





23051
GATTCCCCAC CTCTCCCTTA ACCCTTACCC ACTCTCCTCC CTCCTTCTCT










Exon R4








23101
GTGCAGGTTT CACCCATCGG AGCTCTGTAC CCACCACCAG CAGTGAGTAT





23151
TCAACCGATG CTCCAGTAGC CCCAATTATA CACCAAGCAG GGCAGGAGCT





23201
GTCCTGTCTT CCTATGCCCC TATGTCCTCT TCATAAAGGA AGGGGCTGGG





23251
AGGGCACAAG TTATTCCCTT TCCCTTCTGG CCAGCTCCAG AGAGAGACCC





23301
AGCTCAGGCC CGATATGCAG CAAGGCCTGT AAATAGTTTT ATTTGCTGAC





23351
CTTTCTGCCA TGAGAGGCTT GGATGCTTCC CCTGAAGAGG GTTTCTCTGT





23401
AGCTCTTGGG ACTACCACAG TGGACCTGGG AAACTCTGGG GATCCACCCC





23451
TTCTACTGGT CCCTTGAATA AGTACCAGCC AATGGCACCT CTGTTAGAGC





23501
ATGGCTGATG AGTGTAAACA TCTCTTCCAT TATTCAGTCA AATAAAGATG





23551
GAAATTCTTT ATAAATCTAG TGATGATGAG CCAACCAACA AACTTTATTG





23601
AGCATTGTGA CAAGCCCTGG GGCTCTGCCA AATCCTGGGG ATATGGCATG





23651
GATCATGAAA CAATTAATAA TCTCTCCTCT CAGAGAGCTA TTTTTATGAT





23701
GATACTGATG GTGGCAATGA TGATGATGTT GATGGTGATT ATGACCATGA





23751
TGACAATGGT GATGGTGGTG GTGATGATGG TAATGATGAT GATGGTGATG





23801
TTGGTAATGA TGGTGGTGAT TATGACAATA ATGATGGTGA TGGTGACAGG





23851
GATGGTGATG ATTATGATGG TGGTGGTGAT AACAAAGTTA ATGGATAATA





23901
TATGAACTTA TTGGCTACTG AATATGCACC AAAGTGCTAT GCTCAGTGTT





23951
TAACTAGTAC TATTTAATAT GATTTCTAAA AAAAATCTTG AATTATTATA





24001
GGCAGAAGAA TCATGGGAAC CTTTTATTTT GTCACTCACT TTAAGTCCTA





24051
TTGCATATTT TTTAAGTCAA TTGCAAACAC AGTTTCTCTG CTTTGAACAT





24101
TGTGTTTATA TCCAGTCACC CCAATAGTGC ATAAACCTGC TGATTGGAGC





24151
AACTGTGTCT TACTCCCTTG TGCTTCCCTA GTATCTGCTT CAGGACCTTG





24201
TACATGGTAG ATCGACAGAT TTAGATCTAC AGGAAAATAT GGATTTTCCC





24251
AGGGAAGGAA GGAATGAAGT ATGCTTTCTT ATAATGTATG GAAACTTTCC





24301
TCTTCTGCCT TGGTTCAACT TTAGTGTCTG CCAGAGTTTA CACTGGAAAA





24351
CTATATGGCA TCTGCTCCAC TCCCTCATCC ATGACAGACA TCATTAATTG





24401
ATTGCAGCAT TCATGGCAGA CATCACCAAT TGATAATAGC ATTCATTTTC





24451
TCTCAGTTCA AAACAGCTTC AGAATGGTTA CCAAAAAAAA AAAATTCAGT





24501
CGCTACCAAT TCAATTGGAG CTGACTCAGG ATTATGGGAC AGAATTCAAG





24551
AGAGTTAGGT TCCTTGATGA TGTGTAGTGG CTATTTGTTT TCCGGTCCAG





24601
GCTAATNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





24651
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





24701
CTTTGTGCGG CAAAGTTCAG GGGCCCCAAA AATTTCTGTG CCCCAATCAT





24751
GGCGGACCTA GGTTTAGGCA CAAATTCCAG GGATTAAGTC CCTGGAGATG





24801
TTATGGCTTT TGGTTTTCCT AGAAAGGCTC AGCTCAGGCT CAGCTTGGTC





24851
ATGCTGATAT CCTTTCTTCC ACTTGGTCGA TTTGGCTGTT GATACTTATG





24901
TATGCTTCAC GAAGTTTTTG TGCTGTGTTT TTCAGCTCCA TCGGTTGGTT





24951
TATGTTCCTC TCTAAACTGG TTATTCTAGT TAGCAATTCC TTTAACCTTT





25001
CATCAAGGTG CTTAGCTTTG CATTGCATTA GAACATGCTC CTTTAGCTCA





25051
TCGTACTTTT TTATTGCCCA TCTTCTGAAG CCTACTTCTG TCAATTCATC





25101
CATCTGATCC TCCATCCAGT TCTGCACCCT TAATGGAGAG ATGTTGCGGT





25151
CATTTGGAGG AAAAGAGGCA CTCTGGCCTT TTGGGTTTTC AGCATTTTTT





25201
TGTTGATTAT TTCCCATCTT CAGGAGTTTT AGTTTCAGGC TTTGAGGCTG





25251
CTGATCCTTG GATGGGGTTT TTATGGGGGT CTTTTGGTTG TTGTTGTTGA





25301
TGATGATGAT GTTATTGTCA CTTTCTGCTT GTTTTTCTTT CAATAGTCAG





25351
GTCCCTCTTC TGTAGGGCTG CTGCAGTTTG CTAGGGGTTC ACTTCAGGCC





25401
CTATTCATCT GATTCGCTCC CATGTCTGGA GGTGTCACTC AAGGAGGCTT





25451
GGAGAGCAGC GAACATAGGT GCCTGCTTCT TCTGGGACCT CTGACCTCGA





25501
GGGACACCAA CCTGATGCCA GTAGGATCGC TCCTGTGTAG GGTGTCTGAC





25551
AACTATTGTT GGAGGGTTTC GCCCAGTTGA CTGGCATGGA GAGCAGGACC





25601
CATTTAATGA AGCACTTTGT CCCCTGGTGG AGAGGGGGTT CTTCACTGGG





25651
GGGAAACCAC ATGTCTGGGC TGCTTGGATT CCTCAGAACT ACCAGAGGAG





25701
AGGCTAAGTC TGCTGGTCCA CAGAGACTAC AGCCATCCCT CCCACTAGGG





25751
GCCCAAGCCC AGGGAGTCCA AATTCTGTCT CTGAGCCTCT GGCTGGAGTC





25801
TTTGGAGATC CTGCAAGGAA GCTCTGCCCA CTGAGGAAGG ATGGGTCAGG





25851
GTTAGCCCTG AAGAGGCACT CTGGCTGCAG ACTGCCACAG CCGGTGTGTT





25901
GGGCTGTGGG GACAAGTCTT GGGACCAAGC CGTCCAGCCT ACCCGGCTCT





25951
AGCAGGGGAA AAGTACAGCC TGGAGCTATT GAAAGGGGTG CCGCCCTTCC





26001
CCCGCCCAGG GAGCTTAGCG TGTTAGGCAG TTGTGAGTCC AGTGCTGGCT





26051
GTCGCCCCTT CCCCAAGGAA CAAAAAAGAC TTAGCAGGCA GCCGCAGCCA





26101
GTGCTGGTCG CCCCTCCCCC GGGGAGTTCC GTAGGCTTAG GCAGATTCCA





26151
GCTGTAAGAA TCTGCGTGTT CTGGGGTTGG GACACTAGGT CCCAGTGGCA





26201
TGGGTTCGCG AGTGAGATCT TCCAATCTGT GAGTTGCACA GTTCCGTGGA





26251
AAAAGCACAG TTTCCCCCTC TTGGGTAGCC CGCTCACTCA CCACCTCCCT





26301
TGGCTGGAAG GAGGGGGTTC CCCTTCCCCG TGTGTCTCTC AGGTGGGCCA





26351
CCACACCACA CTGCTCTTCC TTCTCTCTGT GGGTCACTGC CAGCCTTCTA





26401
GTCAATTTTG ATGAGGGAAC CTGGACATTT TGGTTGCCAG GAAGGATCAC





26451
ACACTTATTA CAGTTTTTTT CAATGTGAGC CTCTGAGCGC TGCTGCTTAT





26501
AGTCGACCAT CTTGGCCCCC AGAGTCACAC ATCTGTTATT TTTTGATGTT





26551
TTGATTGTGG CAATTCTTGC AGAAGTAAGG TGGTATCACC TTATGGTTTT





26601
GATTTCCCTG GTCATTAGTG ATGTTGAACA TTTTTTTCAT ATGTTCATTA





26651
GCCATTTGTA TATATTCTTT CAACAACTGT CTATTTATGT CCTTAGCCCA





26701
CTTTTTGATG GGATTGTTTT TTTCTTGCCA ATTTGTTTGA GTTCGTTGTA





26751
GATTCTAGAT ATTAGTCCTT TGTTGGATAT ATAGATTGTG AAGATTTTCT





26801
CCCACTCTGT GGGTTGTCTG TTTACTCTAC TGACTGTGAA GGAAAAGTCA





26851
ATTTCTTATA CGAATTTGTC TCACTCCTAC TTCCAAATGA GATCCTGGGG





26901
TTTTTTTTTT CTGTTAATCC TTCACAATAC TTCTCCCACT TTTTTGAACT





26951
CATTTGTTTA TATTCTGTTG TCTGCTTCTC TTTTATAGGA ATGTGACTTC





27001
TTATGGGCTT TCTCTATTAT ACCACATATG GGTTTTTGTT TTGTTTTGTT





27051
TTGTTTTGTT TTGTTTTTGT CCTCGGATCC ATTCTCCAAC CTCCTCCAGC





27101
CTTCCCGTGC TCTGTGGGAT AGACGTCTGA CTCATGAAAA CTACATTTCC





27151
CAGGCTCCCA TGCTAACTAG CTTCCTGTTA GGTTCAGCCA ATAGGAGGCA





27201
TTGGTGGGAC AATGGTGGGC GGGGCTATGG AAGGGCCAGA GTATTTCTGT





27251
ACCCCGCCCC CCTGCTCCCC TTCCAATGTT CCTGGAGCGG TGTAGGACCA





27301
ATACTGTATA TATGGAAGGA AGGCAAGGTG GATAGATTGG AAGGAAGAAG





27351
TGACAGATGG AAAGAAGAAG TGATAAATGG CAAGCGAGGC AAGGGAGCAG





27401
AGGATGGATG AGTGGATTGC AAGAAAGAAA AAAATGGATG AAATATAAAA





27451
GGAGCAGGAC AGATGGATAA GTAGATGGAA GTAAGAAAAG ACTGGTGTAA





27501
GAAAGGAACG ATTGATGATG GATGATGAAT GGATCAGTGG TGATTGGGTG





27551
AAGGGATGAA TGGATGGATG GACAGATGGA TGAACAGATG GGTGGGTGGA





27601
TAGATGGATG GATGGATAAA ATGGGTAGGT GGATGGATGG ATGGATGGAC





27651
AGATGGGTGG GTAGGTGGAT GGATGGATAG ATGGATGGAT AAGTGAATGG





27701
ATGGATGGAT GGATGGATGG ATAAATGGAT GGATGGGTGA AAGGAAGGAA





27751
AGAAGTGAGA GAAGGAAGAG GAAGGATAGA CAGATGTTAG AAGGTACAAA





27801
TGAAAGGAAG GAAGCCAGCA AGAAAGAAAG GATGCATTAA TAGAATGAAA





27851
GATGGAAGGG AAGAAGAAAG GATGGAAAGA GAGAAGGAAG AATGAACAGA





27901
AGGAAGTTCA AGAGTGGTGA AAAGAAGAAA GGCAGGGAGA GAAGGAGAAG





27951
TAAACTTTTC TTCTAGAGAT TTGTCTTAAA CCTTAGCTTG GCTGGACACT





28001
GTGGTTCACG CCTGTAATCC CAGCACTTTG GGAGGCCGAG GCGGGTGGAT





28051
CATGAGGTCA GGAGATCAAG ACCATCCTGG CTAACACGGT GAAACCCTGT





28101
CTCTACTAAA AATACAAAAA AAATTTAGTC AGGTGTGGTG GTGCATGCCT





28151
GTGGTCCCAG CTACTCAGGA GGCTGAGGCA GGAGAATGGC ATAAAACCTG





28201
GGAGGCAGAG CTTGCAGTGA GCCAAGATCA CACCACTGCA CTCTAGCCTG





28251
GGCGACAAAG TGAGACTCTG TCTCAAACAA AAACAAAACA AAAAAACAAA





28301
AACAAAAAAC AAAACCAAAC CAAAACAAAA AAAAAAACCT TAACTCATAC





28351
TTTCATAAAG TTCCACACAC AGGGAGTGAT TAGAAAGCAT TTGCTGATAT





28401
ATTTTATATA ATAAACATGT ACACCATATT GACCTGTGTG CCCAGCAGTG





28451
CTTACATGAT TTACAATGAT TAACTTGTTT AAGCTTCATA ACAACGGTTG





28501
AGGCAGGAAA CATCATTGTG AACCATTGTC ATCTCATTTT ACAGATGAGT





28551
AAACTGAAGT GCTGAGAGGT TGGTTATGGC TGCAAAGATT GTTGGCCATG





28601
TTAACCAATG CATAGAAGAT TAGCATACCT GGTTGTGAGT GCAGGAGAGA





28651
GAGAGAAATG GGAGAAAGGC AGAGAAGGAT CGATGGGGAG AGAGGAAGAG





28701
AGAGAGAGAG AATAAATTTT TTAAAAATGT CTAGAGTCAT GACTTCCGCA





28751
TCAGTGTGGT AATATGCAGC CTTTACCCTG GGAAAGATCA GAACCATTGG





28801
TACTTTTTAC AGAATCTTCC CTTCCTGCAT TTGGGTAGAA GGACCCCATC





28851
TGGACATCCC AAATCATTAA GCACACCCTT ACTGGCTGCT GGAGTTGTCT





28901
CCATTAAAAG TCACCGTTGG GTTTATTAAG AGGCGGACAC AGGGTCCTTA





28951
GAACACACTG CCCCCACCTG TCCCACACCA CCCCCCACCC ACCCATCATC










Exon R1








29001
CTCCCCAAGA GCTTCATCTC TCTCTCTCTT CCCCCTGCCC TAGCCGGGGT





29051

GGTCAGCGAG GAGCCATTCA CACTGAACTT CACCATCAAC AACCTGCGCT






29101

ACATGGCGGA CATGGGCCAA CCCGGCTCCC TCAAGTTCAA CATCACAGAC






29151

AACGTCATGC AGCACCTGGT GAGAGGCCTG CCTCCCGCTG CAGCCCTGCC






29201
ATGCCCATCC TAGGGCTGTT GCCTGCCTGC CTCTGACCAA CCCAAGCTCC










Exon R2








29251
CTTCTCCCTC TGCAGCTCAG TCCTTTGTTC CAGAGGAGCA GCCTGGGTGC





29301

ACGGTACACA GGCTGCAGGG TCATCGCACT AAGGTGAGAA ACTCCCCCAC






29351
CCACAGCGCA CCACCAAGAA CTTAGAGTTC TGACTGGGAG GTCCCTCTTG





29401
GGTTGGGGTG GGCTACATAT TTTTTTAAAT CTTTTTATCT TTCCTTTTTT





29451
TTTTTTTGAG ATGAAGTTTC GCTCTCGTTG CCCAGGCTAG AGTGCAATGG





29501
CACGATCTTG GCTCACTGCA ACCTCTGCCT CCCGGGTTCA AGTGATTATC





29551
CTGCCTCAGC CTCCCCAGTA GCTGGGATTA CAGGCAGGCA CCACCATGCC





29601
TGGCTAATTG TTTTGTATTT TTAGTAGAGA TGGGGTGTCT CCATGTTGAT





29651
CAGGCTGGTC TTGAACTCCT GACTTCAGGT GATCCACCCT CCTCAGCCTC





29701
CCAAAGTGCT GGGATTACAG GCGTGAGCCA CCATATCTGG CCCCATTCTT





29751
TTTTTTTAAA TGAATTTAAG GAGTGCAAAT GCAGTTTTTG TTACATGCAT





29801
ATATTCCATA GTGAAGTCTG CAGACAGTAG ACTTCCAGAC AGTAGCTTCT





29851
GGTGTATCAC CCGAATAGTG TACATTGTAC TTATTAAGTG AGGTTCCCCA





29901
CCCTTCTCCC ACTCTCCCAC CTTTCTGAGT ATCCAGTGTC TATTATTCCA





29951
CACTCCAGGT CCATGCTCTC ACGTATAAGT GAGAACGTAT GGTATTCCAC





30001
CATGAGCTAA TGGACATGGA GTCCATTGGC TCCCACTTAT AAGTGAGAGC





30051
ATGCGGTATT TGACTATTTC TGAGTTTCAC TTAAGATAAT GGACTCCCAT





30101
TCCATCCATG TTGCTGCAAA ATACATGATT TCACTCTTTT TATGGCTGAA





30151
TAGTATTTCG TGGTATATAT ATATACCACA TTTTCTTTAT CCAGTCTTCT





30201
ACTGATGGAC ACTTAGGTTG GGTCCATACC TTTGCTGTTG AAATAGTGCT





30251
GCAATAAACA TACACGTGCA GGTGTCTTTC TTATATAAAT GATTTCTTTT





30301
TTTCTTTCCT TTTTTTTGAT ATAACGAATT TCTTTTATTT GGGTTAAATC





30351
CCCCAATAGT GGGATTGNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





30401
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





30451
TGACCTGTCC GTATTGATAT ATAAAATGCT GCATTTAAAG TGTACAACTT





30501
GATATTTTGG TATACATTGT TAAATCATGG CCACATTTCA GCTAATTAAT





30551
ATATCTATTA TCTCTACATA GTTATCATGT TTGTACCCTT TGACCAGCAT





30601
CACCCCATTT GCTCCTCCTC CCAGCCCCTG GCAACCACCA TCCTACTCTC





30651
TGCTTCTATG AGTCTGACAA TTTTAGATTC CACCTATAAG TTAGATTATG





30701
CGGTATTTGT CTTTCTGTGC CTGGCTTATT TCACTTAGCC TAATGTCCTC





30751
CAGCTCCATC TATGTTATCC CAAGTGGCAG GATTTTCATC TTTCTTATAT





30801
ATTTCATTGT ATATGTGTAT GCCACATTTT CTTTACCCAT TCATCCATTG





30851
AAGGTCATTT AGCTTGTTTC CATATCTTGG CTATTTTGAA TAGTGCTGCA





30901
ATGAACATAG GAGTGCAGAT ATCTCTTTAA GATACTGGTT TCATTTCTTT





30951
CTTTCTTCTC TTTTTTTTTT TTCTGAGACA GAGTCTGACT CTGTCGCTCA





31001
AGCTGGAGTA CAGTGGTGCA ATCTTGGCTC ACTGCAAACT CTGCCTCCTG





31051
AGTTCAAGCG ATTCTCGTGC CTCAACCTCC CAGGGAGTTT TGCTCTTGCT





31101
GCCCAGGCTG AAGTGCAGTG GTGCAATCTT CACTCACCAC AACCTGTGCC





31151
TCCCGGGTTC AAGCGATTCT CGTGCCTCAG CCTCCCAGGT AGCAAGGATT





31201
ACAGGCGCCC AACACCACAC CAGGCTAAAT TTTTTTGCAT TTTTAGTAGA





31251
GACGGGGTTT TGCCATGTTG GCCAGGCTGG TCTCAAATTC CTGGCCTCAA





31301
GTGATCCACC TGCCTCAGCC TCCTGAAGTG CTGGGATTTT ACAGGCATGA





31351
ACCACCACAC ATGGCCTCAT TTCTTTTAGA TATATATGGG TTGAGCTATT





31401
CTCAGAGGGT CCTTTTCTGC ATCTATTTAA GATCACATTT TTTTTATATT





31451
GTGGCAAAAA TACATGTAAC ATAAAATCTG CCATTTTAAC CATTTTTAAA





31501
TGTACAATTC AGTGACATTG ATTATATTCA CAATGTCATA CAGCCATCAC





31551
CACTATTTAT TTCTAATACT TTTCCATTGG GTAGATCCCC AACAGTGGGA





31601
TTGCTGGGTC AAATGGTAGT TCTGATTTTT TTTTTTTGTT TTTTGAGAAA





31651
TCTCCATACT GTTTTTCATT TGAGGTTGTA CTAATTTACA TTCCCACCAA





31701
CAGTGTATAA GAGTTTCCTA GGCCGGGCAT GGTGGCTTAT GCCTGTAATC





31751
CCAGCACTTT GCGAGGCCCA GGTGGGTGGA TCATGAGGTC AGGAGATCGA





31801
GACCACCCTG GCTAACATGG TGAAACCCCG TCTCTACTAA AAATGCAAAA





31851
AATTAGCCGG GCGTGGTGGC GGGTGCCTGT AGTCCCAGCT ACTGGAGAGG





31901
CTGAGGCAGG AGAATGGCAT GAACCCTGAA GGCGGGGCTT GCAGTGAGCT





31951
GAGATCGCAC CACTGCACAC TTCAACCTAG GCGACAGAGC GAGACTCCAT





32001
CTCAAAAAAA AAAAAAAAAA AAAAGGTTTC CTTTCAGTGC ATCCTTGCCA





32051
ACTTGAGTTT TCTGGGTTGG TTTGCACTCT CATGGTATTT ACTAGATACT





32101
TCTCCATTTA TATTTTTACT CAACCCATGC CCATAACACC ACTCCTCTAC





32151
CATTCCCACC AACCATGTAT AAGAGTTCCT TTTCTTGCAT CCTTGCCAAC





32201
TTGACTTCTT TGGGTCAGTT TGCACTCTCT TGGTATTTAC TATTTACTTC





32251
TCCATTTATA TTTTTAGTCA ACTGATGCCC ATGGCACCGC TCCTCTGAGG





32301
CAGGTGCTGG GTACTAGAGT GATAAGACAG ATGCTGTCCC TGCCCTCACC





32351
CAGTGGAGAA GAACAGATGC TAAACAGGAA CATAAATATC TAAGTAAAAT





32401
GGCTTCAAAT GGAGTAAAGT GATATGAAAC ATAAATAAAT AGCAAGTGAT





32451
GGGTAGAGCA ACTTTACCCA GGATGAATCT TGGGCTGTGT CCCAAATGGC





32501
CATGAAAACT GTTCCAGGCA GGGAGAACAG CATGAGAAAA GGTCTTGAGG





32551
TGCAAATGAG CTTGGCATGT TCTATGAACA GCAAAGAGGC CAGTGTGGCT





32601
GGAGCAGAGA GAGAGCAAGA AGAAAAGAGA GAAAGGATGA GACTCAAGAC





32651
ATCAGCAAGT TTGAAGGGCC TTGGAGGACT TGGATTTTTT TTTTTAAGAC





32701
AGCTTTGTTC TTGTTGCCCA GGCATGATCT CGGCTCACCA CAACCTCCGC





32751
CTCCTGGGTT CAAACGATTC CTCTGCCTCA GCCTCCCGAG TAGCTGGGGG





32801
TAACAGGCAT GTGCCCACCA CACCTGGCTA ATTTTGTATT TTTAGTAGAA





32851
ATGGGGCTTC TCCATGGTTG GTCAGGCTGG TCTCGAACTC CCGACCTCAG





32901
GTGATCCGAC CGCCTCGGCC TCCCAAAGTG CTGGGATTAT AGGTGTGAGC





32951
CACTGCACCT GGCTTGGATT TTTTTTGTTC TATATTGTGG TAACATACAC





33001
ATCACATTAA ATTGATCATT TTAGCTATAT TTCCCGTTCA GTGGCATCAA





33051
GCACATTCAC ATTATTGTGC AACCATCACC ACTATCATCC ATCTCCAGAA





33101
CTTTCTCATC TTCCCAAACT GAAACTCCAT CCCCATGAAA CACTCATTCC





33151
TCATCCCCCT CCTCAAGCCT CTGGCACCCA CCATTCTACT TTCTGTCTCT





33201
GTGAATCTGA TGATTCTGAG GACCTCCTAT GAATGGAGGA ATCATATGGT





33251
ATATGTCCTG GTTTATACTG TATGGCTGGC TTATTTCACC AAGCATAATG





33301
TCCTCAAAGT TCATCCATGT TGTAGCATGT GTCAGAATTC CCTTCCTTTT





33351
CCACTTGTAT GTAAATGCTG TATTGTGTTT CTCCATTCAT TAGGACTTTG





33401
ATTTTTGCAG GGAGTTGTCA AGGGGTGCTG GGTTCTGGGG CTTCAATATA





33451
ATAAGAGTAA GCTAAACTGG TTCATTTCCT CCTTCGTGGA GACCATGTTC





33501
TGGTAGGAAC AGGAACAAAT AATTTATGAT TACATAGAGG GTGACCAGGG





33551
CAGTGACAGG GGAAGAGTGG AGGATTGTGG GACCCAGAGG AGGCTCCTGA





33601
CCTTGCCTAG GAAGATAGGA GGAGGAAGAG GAGGAGGAAG AGGAGGAGGA





33651
AGAGGAGGAG GAGGAGGAGG AGGGAGTCCT CTAAGCTGAG ACCTGGAGGA





33701
TGACCAGGAA GTTATCCAGG TAAGGAGAAA TGGGGAGAAG CTTCCAGACA





33751
AAAGTAACAG CAATTGCAAA GATCCTGAGA TGATAGATAA GGTCAGGTGG





33801
AGAAAGTGCA AACTGTCAAT GAGACCAAAA TATGGACTGT GAGTTGTGCA





33851
GTGACCACAA GTGGAGAGGT GCTAGGTGGC CTTCATCCCC CAAAGCTGCA










Exon R3








33901
CCTCTCCCTC CTCAGGTCTG TGAAGAACGG TGCTGAGACA CGGGTGGACC





33951

TCCTCTGCAC CTACCTGCAG CCCCTCAGCG GCCCAGGTCT GCCTATCAAG






34001

CAGGTGTTCC ATGAGCTGAG CCAGCAGACC CATGGCATCA CCCGGCTGGG






34051

CCCCTACTCT CTGGACAAAG ACAGCCTCTA CCTTAACGGT GAGCAGCTAT






34101
CAGCCCCATC TCCCTGCCCC ACCCCCCAGC CCCCACTGCA GTCCAGGAGG





34151
GTGTCTGTTT GCCGGTTCTC TAGGGAAAGA CTTGGGGTTC AAGTCTTGGC





34201
ATTACCACTG GCCCTCCCAT AACCACAATG CAAGGTTGGA CTTTGATTAA





34251
TCCCATTTTA CAGATGAAGA AACTGAGGCT TAGACAGGCT AAGCAATTTA





34301
CCTTGACAGT GGTGGAACCA GGATATGAAC TCCACTTGTC AGCATTCGGT





34351
GCTATGATCC ACTCCACATG TTTAACTCAC AGAAGAGTCT TCCTGGTGGG





34401
GGCACTTGGG GGACAAAAAA CACATTTCCG GCTGTGAGCA GTGGCTCACA





34451
CCTGTAATCC CAGCACTTTG GGAGGCCAAG GCGGGCGGAT CACAAGGTCA





34501
AGAGATTGAG ACCACCCTGG ACAACATAGT GAAACCCTGT CTCTACTAAA





34551
AATACAAAAA TTAGCTGGGT GTGGTGGCGC ACGCCTGTAG TCCCACCTAC





34601
TCGGGAGGCT GAGGCAGGAG AATCGCTTGA ACTCGGGAGG CAGAGGTTGC





34651
AGTGAGCCAA GATTGCGCCA TTGCACTCCA GTCTGGGTGA CAAGAGTGAA





34701
ACTCTGTCTC AAAAAAAAAA AAAACAATTT CCCCTCCCTG CTTTCTTCTC





34751
ACCATTGACG AGGGATGGGC TTCTCTCCTA CCTGAGGCCC CCTATACCAG





34801
GAAGATCTAT GGGATCTAAT CTTCAGCGCA CACTGGGCCT CAGCATTGGT





34851
CTAGAACTCA GGATAAGATA GCATTTAAGA AGGCATCCCC TAAATGGGGT





34901
TCTGAGAGGC AAAGCATGAC CGTGGAGAAT TGACAAAATA GCTCGCCTTT





34951
CATCCCCTCC ACCGCCAACC CAAGAACAGT GCTTATCATC ATGACCCCAT





35001
GAGGTGGGCA CCCCATATCA CTTATATGAG GTACCTTTAG GTAGGTACCG





35051
GGATGTGGAG AGACATCCTG GGCTTTCATT ACTCTTATTT TAGCAAAGAG





35101
GGAATCTGAG GCACAGAGAA GGGAAGGGAC TTGCCCATGC CCACAGCGAG





35151
TTTTTGGCTA GTATGGGTCT TGATGTTCTT TCTGGGTCCG TNNNNNNNNN





35201
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





35251
NNNNNNNNNT TCCTGCGTGG GAGATGTGTG GATTTGATTT GTATCTGGAA





35301
AGATGATTTT TTATTGGTGA CAAAGCAGTT AAAGTTAATC TTCACAGTTG





35351
TGCGGAGAGT GACCACGCGA GTTAGTCTTA TCCTTATTTT TTTGATCATC





35401
CCGCTACACA AGACAAAGCG AACCGCACAG GCAACATCAG CAGGCCCCAT





35451
TGGTGTGTTC CCCTCTATGG GTCCATGTGT TCTCATCATT AGCTCCCACG





35501
TATAAAGTGA GAAGATGGCA GTATTGGTTT TCTGTTCCTG CATTAGTTTG





35551
GTAAGGATAA TGACCTCCAG CTCCAACCAT GTTCCTGCAA CGGACATGAT





35601
CTCATTCTTT TTTATAGCTG CATAGTATTC CATGGTGTAT ATGTTCCTCA





35651
TGTTCTTTAT CCAGTCTATC CTTGATGGGC ATTTAAGTAG ATTCCATGTC





35701
TTTGCTATTG TGAATAGTGC TTCAGTGAAC AGGTGTCTTT ATGATAGAAA





35751
AATTTATATG CCTTTGGGCA TATATGCAGT GATGAGATTG CTGGGTCAGA





35801
CGGTAGTTCT GTTTTTAGCT CTTTGAGGAA TCATCCTGCT GCTTTCTACA





35851
GTGGATGAAC TAATTTACAC TCCCACCAAC AGTGTATAAA CACTCCTTTT





35901
TATCTGCAAC CTCAGCAGCA TGGTTTTATT TCTCTTTATG GCTGAATAGT





35951
GTTCCATTGT GCATATATAC CACACTTTCT TTATGGATTC ATCTGCTGAT





36001
GGACATATAG GTTGATTCCA CATCTCTGCT ATTGTGAATA GTGCTGTGAT





36051
AAACACACAG GTGCGGGTTG GGTCTTGATG ATCTCAGTTA ACATCCAGTC





36101
CCTTCAACTT GGCTATTGCA GGGAGCTGTT CCCCCTTGTA AACTGCACAG





36151
CTTATGTGCT TCATTTTGTT CCTTCATTTA GATTTACCAA GCAGCTACTA





36201
TTAACCAGGC CACAATGTGC CTCGCCCCCA GGAACAGAGA TAGGTTACAT





36251
GTGCATCCTG TCCTAATGTA ATCTCCAGGG GGGCGGAGAC TGTTTTGTTC





36301
TACCCTATAT TCCCCAAATG TAAAGGGAGC CTTGCACATA CTAAGCCCTT





36351
AATAAACATT CATTGGGTGG AGGAATAGAT TGGAGGAGGC CTGGAAGGGG





36401
AGGCGGGGGT TATGGATGGA TAGGAGGATA GACTTGTGAA CACAAAGGTA





36451
GTGAGAGCCT CTCATTGGAG GCATGCTGGA GACGTGAGTA GGGAAGGGTC





36501
AGTGCTAATT GAAATATCAG GAAATTCTTT CTAGTGGTGA ACACATTTAA





36551
GTCAAATATT AGATGATACA TAAATGTATC CATAATCTCT AGATACACAA





36601
AGGGAAAGGC ATCCAGGCAG GGGCCCCATA TGGACAAAGG CATGGAGTAT





36651
CTGGGACGGT TCCACCACCT CCTCTTACGT GTGACTTCTT TGTTTCAAGG










Exon R4








36701
TTACAATGAA CCTGGTCTAG ATGAGCCTCC TACAAGTACG TGTCTTTGAA





36751
TCTAGTGCCC ATTTCAATCT CCATGGGTCT TGGTTCAAGC TTTTCTCCTC





36801
ATTCATGAAG GAAGGTTGCC CCAAATTCGG GCTGGTCCCC TAGGTGGTGA





36851
GGGGCATTGT CTCAGTGGGA GGAAGAATGC TGAGTCCTTG GCCCTGTTTT





36901
TAGACCTGCA GCCATAGTCT TGGCTTTGTG AATTTTCCAT GTCCCTCTGG





36951
GTTGGAGGAA GAAGTTTGAA CAAGCATTCC CTACACGGGA TAGAGGTTGA





37001
GGTCAGATGA TGACCTCTGT TAGTCTGTAC CCTCCTTGAT AAGAAAATCT





37051
CCTCCAAGTG CCCCAGCAGA GGCTTCATGG TCAAGCTGCA GACTCTGCTG





37101
GCTACTGGTT TTGGCTAAAT TTGCCCATTG CCTCATCCAG TGATCCACTC





37151
GTCTATCTTT CCAGCCATCC ATTTTTCTAT CCTTCCAGTC ATCTCTCAGA





37201
CACCACCTGT CCTTCCATCC ATCCATCCGT CCATCCATTT ACCCATCCAT





37251
CCATCCACCC CATTTTCCTG ACCATTTACC TCCTCGTCCT TCCTTCCATC





37301
TGTCCTTTTA TCCATCTATT CATCCATCAC CCATCCTCCT GCCCATTCAC





37351
CTGCTTGTCC CTCCTTTCTT CTGTCCTTCT ATACATCCAT CCATCCATCC





37401
ATCCATCCAT CCACCCATCC ACTCATCCAC CACCCACCCA TCCTTCTGCC





37451
CACTCACTCG CTAGCCCCTC CTTCCTTCTG TCCTTCCATC CATCCATCCA





37501
CCCATCTTCC TGCCCATTCA CCTGCTTGTC CTTCCTTCTA TCTGTCTTTT





37551
ATCCATCTCT CCATCCATTC TCACCATCCA TCCATCCATC CTTCTCCCTA





37601
TTCACTGGTT TGTCTTTCCT TCTGTCCTTC CAACCATCCA CCCATCTCTC





37651
CATTCATTCT CCTCTTCATT CACCATGTTT CCTTATTTCT GTCTCTTCCA





37701
TCCATCCATC TATCCAGACA GACATCTCCT CCCCCCATTC TCCTCCCCAT





37751
TCACTCAATT GTCCTTCCTT CCATCTGTCC TTTTATCCAT CCATCCACCC





37801
ATCCATCCAT CCATCTATCC TTCTCCCCAT TCACCTGTTT GTCCTTCTTT





37851
CTGTCCTTCC AACCATCCAT CCATCCATCA TCCATCCATC TATCCTTTTC





37901
CCCATTCACC TGTTTTGTCC TTCCTTCTGT CCTTCCAACA TCCCTCCATC





37951
TCTCCATCCA TCCTCCTGCC TATTCATCTG CTTGTCTTTC CTTCCTTCTG





38001
TCCTTCCATC CATTCATCCA TCTGCCCATC CACCCACTCA TCCTCTTGCC





38051
CATTCACCTG CTTGTCCTTC CTTCCACCTG TCCTTTTATC CATCCATCCA





38101
TCCATCCATC TTGCTCACTC CTCCACTCAC ACAATCACTC CTTCCCTCAG





38151
TCTCATTTAT GGCCCACCTG TGAATGGTTG TCCTGGCTTG GACCACTGAT





38201
GAAGCCCAGG GGAGCTTCTC CCACTAGTGG TGGGCTTTTG TCCTCTCTGA










Exon R5








38251
TGGACTGTTC CTTCCACAGC TCCCAAGCCA GCCACCACAT TCCTGCCTCC





38301

TCTGTCAGAA GCCACAACAG GTATTTGGGG CCATTTTTCC TCCTCGAAGA






38351
TTAGAATAGC ATTTCAATCA GACACCTGCC CTCGTGGAGT CCCAGATTTT





38401
ATGAAATAAA TAGACCATCA TAATGTCAGA TGTTTTGGGG TGAGATACCT





38451
GGCATAGTTG GGAAGGAGGA GGGCTTTCTG GAGAAAGTTT CACCTGAACT





38501
GAGTCTTTAA GGATGACTAA GAGTGATTCA GGCAAATAGG GCATGAATAG





38551
TATAACTGAA AGAGGGGAAT CTGTGAGCAA AGCCTCAGTG GCCAGAAACA





38601
GCATAGAGTA TAGGGAGAAG TGAGAGAAAT TTGGTTTGCA TGAAACATAA





38651
AGCTTAACCC AGAGTGGATG GATAAGTGAG ACTGAAAGGT CAGCAGGAGC





38701
CAGATTGGGA AGGGCCTTGA ATGCCAAGTC AAGAAATTTG AACTTAACAC





38751
TGAAGGCCAT AGGGAGCTGT GGATGGTACT AGAGCAGGGG CAGCCATAGT





38801
GAGATTGTCA TTTCAGAAAG ATTCTTCTTG TGTTCAGTAT AGAGAATGTC





38851
CTTTAGACAG GGCATCCAGT GAGTCTGCCA GGTGCTAATC AGGGTGAGAG





38901
AAAATAAGAC CTGAACTGGG ATAGGGGGAG GAGAGAGAGG ATATATGTGA





38951
TGAATATTCA GTAAAGAGAA TTGGTGTTAC TTGGAGGGGA GAAGACACAT





39001
AGCTTCTGAC TTGCGATGGC CACACTCAGT TTAATAATGA GCGCAGTCTG





39051
ATCTAGTCTC AGACCAGCCC TCAGTTGCAG ACGTCTCTCC TCCCCTCCTG










Exon R1








39101
CAGCATGGGG TACCACCTGA AGACCCTCAC ACTCAACTTC ACCATCTCCA





39151

ATCTCCAGTA TTCACCAGAT ATGGGCAAGG GCTCAGCTAC ATTCAACTCC






39201

ACCGAGGGGG TCCTTCAGCA CCTGGTGAGA CCCTGGTCCC AGCAGCTCCT






39251
GGTGGGATAA ATCCTACCCC CAACCTCTGT TCCTCGGCTT ACCCTCTTCC










Exon R2








39301
TCCTTCCTCT CAAGCTCAGA CCCTTGTTCC AGAAGAGCAG CATGGGCCCC





39351

TTCTACTTGG GTTGCCAACT GATCTCCCTC AGGTGAGACC ACTTCCTGGC






39401
CATTTGCCAG TAACAACCAC CCCTTTTGTG ACCACCCCTT CCTCAGCTTT





39451
CCCCTGCTCC TCCCTCCACT GCTCTTTACC TGCAGAGGTC TCGGGACCTC










Exon R3








39501
TCTAGAGTCC TCAAATGCCT CTCTCCCCAG GCCTGAGAAG GATGGGGCAG





39551

CCACTGGTGT GGACACCACC TGCACCTACC ACCCTGACCC TGTGGGCCCC






39601

GGGCTGGACA TACAGCAGCT TTACTGGGAG CTGAGTCAGC TGACCCATGG






39651

TGTCACCCAA CTGGGCTTCT ATGTCCTGGA CAGGGATAGC CTCTTCATCA






39701

ATGGTGAGTG TCAGGCTGAA CTTGGATTTA CAGTGACTTT TGGGGAGTTG






39751
GTTTCTTTGT TTTTGAGATG GAGTCTCACT CTATCACCCA GGCTGGAGTG





39801
CAATGGTGCA ATCTTGGCTC TGCAACAGTG ATTCTCCTGC CTCAGCCTCC





39851
CAAGTAGCTG GGATTTACAG GTGCATGCCA CCACGCTCAG CTAATTTTTG





39901
TATTTTTAGT AGAGATGGGG TTTCACCATG TTGCCCAGGC TGGTCTCGAA





39951
CTCCTGACCT CAGGTGATCC ACCTGCCTTG GCCTCCCAAA GTGCCAGGAT





40001
TACAGGCATG AGCCACCATG CCCGGCCCAC CATGACTATT ATTTGTCCCT





40051
GTTGTATGCC CTTTCCTCTC TAAAAAAAAT AGCCCAAGGC CTGGCTGGGG





40101
GACACCCTTC CCCAAACCAC CAAGGGGAGG GTCTTTCCCA TTATTTTGAG





40151
TAAATAGCAT GAAATTCTTT GACCAAATTA ATGTCATAAA TTGTTTGTCT





40201
CTTTCTCCTT CACTTTTGTT TCCAACTTGG TTGCGGTATA ACTATCAAAT





40251
ACAATTGTAT GTATTTAAGA TGTATAATGC AGTGATTTAA TATATGTGTA





40301
GCTTATGAAA TGATTACCAT GATCAAATTA GTTAACACTG CTTTCATGTC





40351
ACATAGTTAC CGTGTGTCTG TGTGCGTCTG TGTGAGTTAG AGAGAAAGAG





40401
AACATTTAAG GTCTACCCTC ATAGAAAATT TCAGGTTTAC AATACAGTAT





40451
TATTAACTAT AATCATCAAG CTTTATACTC GATCCCCAGA ACTTATTCAT





40501
CTTGTAACTA AAAGTTTGTA TTTTGTGACC AACATCTCCC CATTTTCTCT





40551
ATCACCACCC CCATGCCCCC AGCCCCTGAT AACCATCATG CTACTCTCTG





40601
CTTCTGTAAG TTTGACTTCT GATCCCACAT ATAAGTGAGA TCATGCAGTA





40651
TTTGTTTCTC TCTATCTGGT ATATTTCACT TAGCATAATG AACCCCCCCC





40701
AGGTACATCC ATAATGAATT TCAATTCAAA ACCCAAGTGG CTGAGTCGTG





40751
GCATCCTTTG GGACAGGATA GCAGGTCCCT TCTATATAAG GATCCTCTGT





40801
GTCAGTGGTT ATTACCAGGG GACAATTCTG CACTTCTGCC CCACCCCACC





40851
CCCCAACTGG GAGACTCTAG GCAATATCCG AAATCATTTT TGGGTATCAC





40901
AACTCAGGGA GGGAAGGAGG GTGCAACTGG CACCTAGTGG GTCGGTAGCC





40951
CATTTTCCAG TGCACAGGAG ACAACCACCC CAGGGAATGA TCCAGCCCCA





41001
AATGCCAATA ATTTCAAGGG TGAGAAATCC TGTTGTACAT GGTCTCAAAG





41051
TTCTTAGGTG GGCACAAGGC TGACATTTAT CACACTTTAC TGTAATTACT





41101
TGTTAAATTT ATCTGATTCC CCCTTACCCT GTGAACTCAA CAAAATTACG





41151
GTCTATTATG AGTGCCACTG TACCCTCGGT TCGCAGTACA TCAGCACATC





41201
ATAGTATGGA AAGAATCATT GAATGAGTGA GCAAATTAAA GATTTGTGTC





41251
TCTGCTGTAA CTCACATTCA TTAATTCATT CATTCAGCAA ACATATATGG





41301
GTGGCTGTTC TGCCCCAAGC CTTGTACTGG GTCTGGAGAT AGAAGACACA





41351
TTTTTCTGTC TCTGAAAAAC TCATACTCAA GTTAACAACA AATTACGGGC





41401
ACAACAAAGA CCCCACTGCT GTTATTAACA GGGTACTATG GGAGCTGAGA





41451
GGAGGAGTAA ATTAAGGAGG GCTTCCTGGA GGAGGGTGTT ATATACCCGG





41501
CCCTGTGCCG GGACACATAA TGATAAGACA GACTTGGGCC TCTGCTGTCC





41551
TGGAGCTCCC TCTCACTGGG CTCTTGAAGC GTGAGCAGGA GTTTTGCAGG





41601
AAATGAAAAG GATGCATTCC TAGAAGTGGG AACTGCATAG CACATGCAGG





41651
AAAGCTCAGC TCAGAAGAAT CTGTGTAATA TTCCATTTTT CCCTCTCTTT





41701
GGGGCAACTT TCTGTCTAAG AGCTCCTGCA ATGCCCAGCG TGTGGACCTG





41751
AAATTGATTC TGACAGTAGG CAGGGGACTG CTGGGCAACT TTGGCTCTGC





41801
ATTTTGTGAT CAACATTTCC CCACCATATG TTGCCTTTTC TTCTTCTCTG










Exon R4








41851
TGGCTCCAGG CTATGCACCC CAGAATTTAT CAATCCGGGG CGAGTACCAG





41901

ATAAATTTCC ACATTGTCAA CTGGAACCTC AGTAATCCAG ACCCCACATC






41951

CTCAGAGTAC ATCACCCTGC TGAGGGACAT CCAGGACAAG GTGGGGCATC






42001
TCTCACCCCT CCCGTCTTCT CTGTCCTGTG TGCTTCTCTC CCTCTTCTAC





42051
CTGATTTCTC TGTTAAGTGA TCACTTTAAA TGCTTCACTT CACTATGTAT





42101
TCTGGGTTCT CTCTCAGTTT CCAAAAGTAC TCTCTTGACT ACCATTCCCA





42151
TTTCACAGAT GGGCAAACTG AGGCTCAGAA AGGGGCGTGG TGTGCCTAGG





42201
GTCATACAGT GCTTTAGGAA CAGAGTTAGG ATTTGAACTC TGGTCCCCTT





42251
TGCTCCAAGT CCTGTGTTTT TTTCCACTGG CATCAGCGGC CCCTCCACCC





42301
CCAAGAGGCC TCCATCTCAC CCACTCTCCC TACCCATCTT TCTAGGTC
















TABLE 3





Genomic Carboxy Terminal


(SEQ ID NO: 3)







Exon C1








1
ACCACACTCT ACAAAGGCAG TCAACTACAT GACACATTCC GCTTCTGCCT





51

GGTCACCAAC TTGACGTAAG TTCTGAAGGT CATAAGCAGT GACCAAGCTT






101
GTGGCTGTGT CTCTGAGCAC CCTTGAGCTA GACGTCCCCA GTGGGGTACC





151
CATTCTCCCC TACATCCCTG TCTAGCTAAT CCTACCATCT CCTCCCATAA





201
ATCCTCAAGG TAGGGAGTGA GGATTAACCT CATGGGGCCA CCAACTCCCA





251
GCATACACCT TCTTTTTTTT CTGGACACTT GGGAAAATAT AACTTTTTGA





301
TGTAGAACTC AAAATATTAG CCCAATAATA ATATTTAACA TCAACCAGCC





351
TCCTCTCATT TAATTCTCAC AACAGAATCT ATGAGTTGAG TGCAAAAATC





401
ATCCCTATTG TGCAGATGGG AAAACTGAGG GTCAGAAAAG TGAACTTCCC





451
AAGAACTGTC AAAGTTGGGA TTTGAACCCA GGTCTCTGAT GACTGGATGA





501
AGGAATGAAG ATACCTATAC TTGGGAATGA GGAGGGTCGA CAGGACACGA





551
GGGCTGACTT TGTATATTTC TAAACTTCAA AGATTTTCTG TATTTCAGCT





601
GGGAATATGG TAGAAGGTTA ATTGGAACAA AAAAATGCAA AGCAATGAAT





651
AAGACCTCAG TATTTGCTAT GCACAACAGG GTGACTGTAG TCCCACAAAT





701
AACTTCACTG TACATTGTTA AAATATAACT AAAGGTGTAT GCTTGGATTG





751
TTTGCAACAC AAAGGATATA TGCTTGAGGG GATGGATACC CCATTTACCC





801
TGATGATTAT TATGCATTAC ATGCTTGTAT CAAAACATCT CATATACCCC





851
ATAAATATAA AAACACCTAC TATGTACCCC AAAAAATTAA AAACAAATAA





1051
AGGCATGGTG GCACACACCT GTAGTCCCAG CCACTCAGGA AGCTGAGGTG





1101
GGAGGATCGC CTGAGCCTAG GAGGCTGTAC TCCAGCCTGG GTGACAGAGC





1151
GAGACTCTAT CTCAAAAAAT AAAATAAAAT AATAAAAAGT AGAAATCAAG





1201
AGGGAAAATG TGGGAGAAAT TGGGATAATT TTAACAATAC CTTCCACCAG





1251
AGTGATGATG AAGAATGCAT AAGTCACTTC TTAGTGGTCT TGATCTATAA





1301
AAAGTGTTCA ATAAATATCG ATTATTGTTA CTGTTATTGC TTCTAGACGT





1351
AATTCCTGGA AGCATTTTTT TTTTTTTTTT TTTTGAGATG GAGTCATGCT





1401
CTGTTGCTCA GGCTGGAGTG CAGTGGTATG ATCTCGGCTC ACTACAACTG





1451
CCTCCTGGGT TCAAGCAATT CTCCTGCCTC AGCCCCCCAT GTAGCAGGGA





1501
CTACAGGCAT GCGCCACCAC ACCCGGTGAA GTTTTGTATT TTTATTAGAG





1551
ACAGGGTTTT GCCATGTTGG TCAGGCTGGT CTCGAACTCC TGACCTCAGG





1601
CAATTTGCCT GCCTCGGCCT CCCAAAGTGC TGAGATTACA GGCTTGGGCC





1651
ACTGCATCCA GCCGAAGGCC TCCCATTTTG ATCAGAACCC TTCTCTAGAC





1701
TGAGGGTGGG TGCCTCTAGA TCTTTTGCTC TTTAAAGACA GCAACCGATG





1751
ACCCTGCTGA TGCTGAGTAC TGGCTGAATT CCTGTGGTCT CTGTCCCTAG










Exon C2








1801
GATGGACTCC GTGTTGGTCA CTGTCAAGGC ATTGTTCTCC TCCAATTTGG





1851

ACCCCAGCCT GGTGGAGCAA GTCTTTCTAG ATAAGACCCT GAATGCCTCA






1901

TTCCATTGGC TGGGCTCCAC CTACCAGTTG GTGGACATCC ATGTGACAGG






1951
TACAAGGTGG GGTGGCTGGT TTCCTAACTG GAAGAGGTGG GGTTATGAGG





2001
AAAGATGGGG CTTCTCGGTA CCAGTGGAAT TGGTGGAGGC TCTAGAGAGG





2051
GAAAGGGAGG CTTTCTGGAG ACCCATGTAG GTGACCTCTG GCAGTAGATC





2101
ATCCAACGAG GCAGGAACAG AACACCAGCC ATTGCATCTA AGAGAATAGC





2151
TATTTTTACA TGTAAAAAGA ATTGTGTTGA ATGAATGAAT CAATAGATCA





2201
TTTATTTTGA ATCAATTTAT TGATTCATTC ATTTAATTAA TGAATAATAA





2251
ATGATTCAGT ACATAATTGA TTAATTGATG TAATTGAGAA TTGATTTAAT





2301
TGATTAATTG ATCAATTAAA ATGATCAATT AAATGAATGA ATCAGTAAAT





2351
GAATAATTCA TTCATTCAAT AAACAATGGA AGTAGGCCGG GCATGGTGGC





2401
TCACGCCTGT AATACCAGTA CTTTGGGAGG CCCAGGCAGG CAGATCACGA





2451
GGTCAGGAGA TTGAGACCAT CCTGGCTAAC ACGGTGAAAC CCTGTCTCTA





2501
CTAAAAATAC AAAAAAAATT AGCCAGGCAT GGTGGTGGCC ACCTGTAGTC





2551
GCAGCTACTC GGGAGGCTGA GGCAGGAGAA TGGCGTGAAC CCGGGAGGCA





2601
GAGCTTGCAG TGAGCCGAGA TCGCGCCACT GCACTCCAGC CTGGGCGACA





2651
GATGGAGACT CTGTCTCAAA AATAAATAAA TAAATAAAAA TAAAAAATAA





2701
ATAAACAATG GAAGTAAACA CGTACTGATA ACACAGTGTG ATCATTGCTA





2751
TGATAAGGGA ATTTCAGGGG CCTGTGGGAG CCCCAAGGAG GAACACACAA





2801
CCTTGTCTTG GAAAGTTTTA TGTAGGAAGG GGTGAAGAAG CTGAGATCTG





2851
ACAGAGAATG GGACCTAGCC AGGGGTAATA GATGGAGAAT TGTGCTCCAT





2901
GCATCTATAA CCTAGAAGAT AGAAAGAATA TGGCATCTGG CCGGGTGCGG





2951
TGGCTCACGC CTGTAGTCCC AGCACTTTCA GAGGCTGAGA TGGGTGGATC





3001
ACCTGAGGTC AGGAGTTCAA GACCAGCCTG ACCAATATGA TGAAACCCCA





3051
TCTCTGCTAA AAATACAAAA ATTAGCCAGG CATGGTGGTG CGTGCCTGTA





3101
ATCCCAGCCA CTTGGGAGGC TGAGAGAGGA GAACTGCTTG AACTCGGGAG





3151
GCGGAGGTTG CAGTGAGCCG AGATTGTGCC ATTGCACTCA AGCCTGGGCA





3201
AAAAGAGCAA AACTGCATTT CAAAAAAAAA AAAAGTGGCA TTTTGGGGCA





3251
AGTTTAAGAA GATTGGTGTA GCTGGAGCAT CCACTTTGAT ACTGGAGAGG





3301
TGACAGTTGA AGCCAAAGAT GTGGGCAGAG ACTTTGTTGG GCACTGGAAT





3351
GGCTTGGGGA GGAACATGAC ACACTCATGA GTTCTGCTTT AGAAAGAAAA





3401
TGAAATGAAT TCTGCTCATC CTCTGGGTGC TGTGTGCAGA ATGGAGGGTG





3451
GGGGGAGAGA AGAGCAAAGG CAAGAAGACC CTTTAGGAAC AATGATCATT





3501
AGTTAGAAGA CTCTGGGTTT CTCAGCACCT GCAATTGCTG ACTACACCCC





3551
CAGAGAAACC CAGTCTCTTT TCCCCCATGT TGTAGAGAAT TCTTACAATG





3601
CTTGGTAGAA AGAGAATTGA ACAGGTAGAT GGGTGGATGG ATACAAGCTG





3651
GACAGATGGA TGGAGGAAGA TCCTCCATCC AATATAGAGC TGTTACCTAA





3701
AACCCTCCAT CCCACCTTTA AAATCCTAGC TCAGCCAGGC GCGGTGGCTC





3751
ACACCTGTAA TCCCAGCACT TTGGGAGGCC AAGGCGGGTG GATCACTTGA





3801
GGTCGGGGGT TCGAGACCAG TCTGACCAAC ATGGTGAAAC CCCCTTCTCC





3851
ACTAAAAATA CAAAAAAAAA AAAAAGTTAG CCAGGCAGGG TGGCGCATGC





3901
CTGTAATCCC GCTACTCGGG AGGCTGAGGC AGGAGAATGG CTTGCACCCA





3951
GGAGGTGGAG GTTGTGGTGA GCCAAGATCA CGCCATTACA CTCCAGCCTG





4001
GGCAAAGAGA GTGAAACTGT CTCAAAAAAC AAAACAAATG ACCCCCCTGC





4051
CAAAAAAAAA AAAAAAAAAA AAGAAAAGAA AAAAAGAAAA GCCTAGCTCA





4101
GCTCACACTG TCAGGAATAA GTAAGCTAGC TGGAATCATC TCTTTCTTAA










Exon C3








4151
AACCCTGCCT TGATAGTGGA TTTTTACATA CTTTTTTTTT AATTCTAGAA





4201

ATGGAGTCAT CAGTTTATCA ACCAACAAGC AGCTCCAGCA CCCAGCACTT






4251

CTACCTGAAT TTCACCATCA CCAACCTACC ATATTCCCAG GACAAAGCCC






4301

AGCCAGGCAC CACCAATTAC CAGAGGAACA AAAGGAATAT TGAGGATGCG






4351
GTGAGAAGGG GGTGGTATGT CCACTCTGTT GCCATGCAGA AACTGACTTA





4401
TGCATACTGG GTAGCCACAG GGTGACTTTT TATAACAATC CACAAAGACA





4451
GGTTCTTATT CCCATTTAAT ACACAAGCAC AGAGAGGTTC AGTAGCTGAC





4501
CCAAGGTCAC ACAGCTAAGT CATACCCTAG AAGAGCATGT CCTTTGATAT





4551
ACATACCTGG GCAAGTGGTT GTCATGACAA GAAGCAAAAT AGACGGAGAA





4601
GTGTGCTCAG TGGCTGAAAA TTCTCTGATG CTACTGGGGC CAGGATTCTG










Exon C4








4651
ACCTAAGAAA CATCGCCCTG TCTTTCAGCT CAACCAACTC TTCCGAAACA





4701

GCAGCATCAA GAGTTATTTT TCTGACTGTC AAGTTTCAAC ATTCAGGTAA






4751
GTTCTAACTC AGGACCTAAT GACTCTAGGA ACTTCTGCTG TCCTTTAAAT





4801
AGAAGTGTCC CCAAGCCATA GCTTTGATGG AAGAGAGCCC TAGAAATAGA





4851
GAGCTGTTAA CTAAAAACTA GCTTTTTCCT AAAGCTGGAG CCCAACTGGC





4901
TTCAACACTC AAGAGAGCTG GTGTAAATCT CAGCAGACAT AAAGGTACCT





4951
GGTGCTGAGG CCATGGAGTC TAGAGTGTAG AATCTACTAC ATTAAGACAT





5001
CAGCTACTGA AATCAGGACC CATGGAAGAC GGGGGAAGGA GGGGACTAAA





5051
ACCAGATTAC TTAGAATCTA GCAGCCTAAC TGTGCTTTTC AATGAGAGGT





5101
ATCATTTCCA ATGGTGGGGG GTACCAATGA TTTTTTTTTT TTGACAACTG





5151
CCTTGAGAAC AGGCTTTCCT CACTAAACAA ATTCTGAATC AGAACAAATA





5201
AAGATAAGCC CTGAGAATAG GGCTTTTTCA AGGAGCTGCC AAACAGATCA





5251
AATAGTGACT ATGTTCTGCA GATTGATGTC TGGAGAACTC TACAGCTATT





5301
TTGACTGCTA GGCAGCTGGT TTTCACAGAT ATCATGATTC TGAGGCTGCC





5351
AGTTTTCAAA GTTACCGAGG ATCTTGCTGG ATGCAGTGGC TTGCGACTGT





5401
AATCCCAGCC CTTTGGGAGG CCAAGGTGGG TAGATCGCTT GAGCTCAGGA





5451
GTTTGAGACC AGCCTGGGCA ATATGGTGAA AACCCATCTC TACAAAAAAT





5501
ACAAAAATCA GCTGAGCATA GTGGCATGTG CTGTAGTCCC AGTTACTTAG





5551
GAGGCTGAGG TGGGAGGATG GCTTGAGCCC AGGAGGCAGA GGTTGCAGTG





5601
AGCTGACATT GTGCCATGCA CTCTAGCCTG GGCAACAGAG CCAAAGCCTG





5651
TCTCAAAAAA AAAAAAACAA ATAATAATAA TAATAAAATA CTGAGGATCT





5701
TGAAAGAGCA CTGTGGAAAT AATGCAAGTT AAAATGCCAC AAAGCTTGCT





5751
CTTTTTACTG AGATTTAACA CTTTCCTTAA CTAAACACCC CTCGAATTTT





5801
TGCAAGCCTT TGGTTCACTT CTAGACTTCT GGAAAAATTG ATTTGGACTA





5851
TTTTGGCCAA TGTTCTCATT GATTTTATGG GTATTCAGAA GTTGTTACCC





5901
CAACATTCCA GAAATGTTCT CCCTGTGGCT ATTACTTTAT TTATTTATTT





5951
ATTTATTTAT TTATTTATTT ATTTGAGACG GAGTCTCCCT CTGTTGCCCA





6001
GGCTGGAGTG CAGTGGCGCA ATCTCAGCTC ACTGCAACCT CCGCTTCCCA





6051
GGTTCAAGCG ATTCTCCTGC CTCAGCCTCC CAAGTAGCTG GGATTATGGA





6101
TGTGCACCAC CACACCGGCT AATTTTTGTG TTTTTAGTAG AGATGGGGTT





6151
TCACTGTGTT GGCCAGGCTG GTCTCGAACT CCTGATCTCA AGTGATCCAC





6201
CCGCCTTGGC CTCCCAAAGT GCTGGGATAA CAGGCATGAG CCACTGTGCC





6251
TGACCTCCCT GTGGCTATTT TTAAATGAAT TAAGTGGAAT AAAATTAGAA





6301
ATTCAGTTCT TCTCCCACGC TAGCTGCATT TTAAGCATTT AATAACAACA





6351
TGAAGCTACT AATGGCTGCA TTGTGTAGTG CAGATGTAGA ATTTTTTTTT





6401
TGTTTTTTGT TTTGTTTTTG AGATGGAGTC TCGCTCTGTC ACCAGGCTAG





6451
AGTGCAGTGG CGTGATCTCG TCTCACTGCA ATCTCTACTC CCCGATTCAA





6501
GTGATTCTCC TGCCTCAGCC TCCCAAGTAG CTGGGATTAC AGGCACGTGC





6551
CACCACACCC AGCTAATATT TGTATGGATG GTCTCAATCT CCTGACCTCG





6601
TGATTTGTAT GGATGGTCTC GATCTGACCT CATGATCCGC CTGCCTGGGC





6651
CTCCCAAAGT GCTGGGATTA CAGGCGTGAG CCACTGTGCC CGGCCGACAT





6701
AGAATGTTTA CATCATTGCA GAAAGTTTCT GCAGGAAGAG CCTAGAAGGA





6751
GAAAGCCTAG AATCATGATA AAATTGCAGA TATCTTTGCT TATCCCTGTC










Exon C5








6801
CCCTTCCAGG TCTGTCCCCA ACAGGCACCA CACCGGGGTG GACTCCCTGT





6851

GTAACTTCTC GCCACTGGCT CGGAGAGTAG ACAGAGTTGC CATCTATGAG






6901

GAATTTCTGC GGATGACCCG GAATGGTACC CAGCTGCAGA ACTTCACCCT






6951

GGACAGGAGC AGTGTCCTTG TGGATGGTAA AGCTCCCTGG GTCATTGGGA






7001
CTGAGGTGGA AGCTCCCACT TCCTCACCTG GGTCCTTCCC TGGGAATCTG





7051
AAGGCTTGGG GTTGATTCGT CATCGAGCTT TCTCAGACTG GGAGAAAGTG





7101
GCTTAGTTCT CCTAAGCTTT ACCCATCATT GAAGGAAAGA AAAGGACGCC





7151
CGAGGGATAT GGGAGGCATT TGCCCTCTTC TGGCCAGCTC TGTGACCTCA





7201
GGCTAGTCAC ATCTCCTTTC TGGACTTCTT ATCTCTCTGT ACTTAGCAAG





7251
CCACTTGGTT TTTGGTTCCC ATCTTGCCTG CCCTAGATGG TATTGCTCCT





7301
CCACCCCCAG GCAGCTGCAG TGTTAAACAA TTACCCTGAT TAGTTATTGT





7351
TGTTGTGTTG TTTGTTTGTT TTTGAGACAG GGTCTCACTC TGTCACCTAG





7401
GCTGGAGTGC AGTGACATGA TCTCAGCTCA CTGCAACCTC AACCCCTGGA





7451
CTCAAGCAAT CCACCCACTT CAGCCTCCCA AGTAACTGGG ACTACAGCCA





7501
TGCGCCACCA CACCCGGATA ATTTTTGTAT TTTTTCTAGA GATGGGGTTT





7551
TGCAACATTG CCCAGGCTGG TCTTGAACTC CTGAGCTCAA GCATGCCACC





7601
TGCTTCAGCC TCCCAAAGTG CTGGGATTAC AGGCAGGCAG GCACCACTGC





7651
AGCTGGTTCT GGTTTTTTGT GTTTGTTTTT TTCTTTTAGA GGCAGGGTCT





7701
CGCTCTGTTA ACCAGAATGG AGTACAGTGG TGCAATCATA GCTCACTGCA





7751
GTCTTGAACT CCTGGGCTCA AGCGATCCTC CCACCTCAGC CTCCTGAGTA





7801
CCTGGAACTA CAGGCACGTG TCACCACGCC TTGCTAATTT CTAAATTTTT





7851
TGTAGAGACA GGGTCTCACT ATGTTGCCCA GACTGGTCTC TAATTCCTGG





7901
CCACAAGTGA TCCTCCTGCC TCAGCAGGTC AATGAGGGCT TCCAGTTTCA





7951
AGTTGTATGT GATTCATCCT CAACAAATGT GGTAGGATGG ACCTATTTTC





8001
CAACTCCAGA GATGGCTTCA AGGTGGCTCA ACTTTGCATA TCCAATTTTA





8051
CCCATTCAAA GAATAGTTAT ATACATTGTA CCATGTATCA GGAATATAAC





8101
AGAGAGTAAC TGTTTGCTCT TTCACCACTA TATTCCAAGA ACCCCATATT





8151
CTGCCTGGCA CATAATAAAC ACTCAAGTCA TATTTGCAGA AGGAATAACT





8201
AGATTTCATA CAAGGTTCTT TTCAAGTCAA ATGCGAATAA CGTTTTAGAC





8251
GGGACCTTCC AATGCCTGTG TGCACTGTCC TTGATTCCGA ATTATTGTTG





8301
TGCAAGAGAG CACTGTTGAT CCTTCAGAAT CAACAAGCCT TTCACATGCC





8351
TGTCACAGGT TTTTCTTTTT CTTGTTTTAC CAATTTTGTT TGTTGTTTGT





8401
TTGTTGTTAT TGTTTTGTTT TGTTTTTGTT TTTTATTTGT TTTTATTTTT





8451
TCTTTTTTTT TGAGACAGAG TCTCGCTCTG TCACCCAGGC TGGAGTGCAG





8501
TGGCACGATC TCCGCCCACT GCAAGCTCCG CCTCCTGGGT TCATGCCATT





8551
TTCCTGCCTC AGCCTCCTGA GTAGCTGGGA CTACAGGCGC CTGCCACCAT





8601
GTCTGGCTAA TTTTTTTTGT ATTTTTAGTA GAAACAGGGT TTCACCATGT





8651
TGACCAGGAT GGTCTCGATC TCCTGACCTC GTGATCTGCC CACCTGGGCC





8701
TCCCAAAGTG CTGGGATTAC AGGCGTGAGC CACCACACCC AGCCCCAATT





8751
TTTTTTTTAA TTAAAATTGT TGTCAGCTCA CAAGCTTTCT AAAAACAGGC





8801
CATGGACCCA GCATCGCTGT AGTTTGCCAA ACCCTTGCCT TGAATCAGTA





8851
CCATCCAATA GAACTTTCTG CAGTGATAGA AAATGTTTCT ATCTGTGCTA





8901
TTCAGCACAA AGCCATGTGT GATTACTAAG CTTGAAGTGT GGTTAATGTA





8951
ACTGAGATAC CGAAGTTTTA ATTTTATTTA ATTTTAATTT AAAAAGCCAC





9001
TTGTGGCTGC TCCATATTGC ACACTACTTT TTAAAATTAT TATTTGTATA





9051
TATTTAAGGG GCACAAGTAC AATTTTGTTG CATGGATTTA TAGCCCAGTG





9101
GGGAAGTCTG GGCTTTTAGG GTATCTATTA CCTGAATAAT GTACATTGTA





9151
CCCATTGAGT AATTTCTCAT CATCCACTCT CCTCCACTCC CCAACCCTTC





9201
CAAGTTTCCA CTGTCTATTA TTCCACTCTC TATGTCCATG CCTATGCATT





9251
ATTTAGCATT GACATGTCTA TGCATTATTT AGTCAAATAC ATGTGCTATT





9301
TGACTTCCTG TATCTGAGTT GTTTGACTTA AGATAATGAC CTTCACTTGC





9351
ATCCATGTTG CTGCAAAAGA CATGATTTCA TTCTTTTTTA TGCCTGGGTG





9401
GTATTGCATT GTGTGTGTGT GTGTGTGTGT GTGTGTAGAG AGAGAGAGAG





9451
ATCACATTTT CTTTATACAG TCCTCCATTG ATGGGCACTT AGGTTGATTC





9501
CATATCTTTG CTATTGTGAA TAGTTTTGTG ATAAACACAC AGGTTCAGGT





9551
GTCTTTTTGA CAAAATTATT TATTTTCCTT TGTGTAGATA CCCAGTCGTG





9601
GGATTCCTGG ATCAAATGGT AGTTTCATTT TTAGTTATTT GAGAAATCTC





9651
CACGTTTTTC ATAGAGATTA TACTAAATTA CATTCCCACC AACAGTGTGT





9701
AACGGTTCAC TTTTCTTGCA TCCTTTTTAA CATCTGTTAT TTTTGTCTTT





9751
TTAGTAACAG CCATTCTGAC TGGCGTAAGG TGGTATCTCA TCATGGTTTT





9801
AATCTGTATT TCTCTGATTA TTAGTAATGT CGAGCATTTT TTCATATGCT





9851
TGTTAGCCAT TGGTATGTCT TCTACATCTT TAAGAAGCTG GCTATGGGCT





9901
GGGCGCAGTG GCTCACACCT GTAATCCCAG CACTTTGGGA GGCCGAGGCA





9951
GGCGGATCAC GAGGTCAGGA GTTAAAAACC AGCCTGGCCA ACATGGTAAA





10001
ACCCTGCCTC TACTAAAAAT ACAAAAAATT ACCCAGGCAT GGTGGTGCGC





10051
CTGTAATCCC AGCTACTCAG GAAGCTGAGG CAGGAGAATC ACTTGAACCC





10101
AGGAGGCGGA GGTTGCAGTG AGACGAGATC ACATCATTGC ACTCCAGCCT





10151
GGGTGACAGA GTGAGACTCT ATCTTGAGAA AAAAAAAAAG TTGGCTATAA





10201
CAGGGTTGTA GAAGTAGAGG AACCAGTAAC CCTTCTCGCC ATGCCTGATG





10251
ATGGCTTTAC ATCCCTGTCT TCATGGAGTT TATGCTGTCG TGAGGAATAA





10301
CAAGAACAGG CAGTTGTCAA TTATAAATTA TTTGATGTGA ACCTATTCAT





10351
ACATGGGTGT GGTCATCAGG GAAGGCTTCC TGGAGGAAAT GACATTGAAG





10401
GTGAATTCTA AAAGATGACG ATAAACCACC AAGTGAAGGA GAGCTTAAAT





10451
GTGTTTTTAG GCAGAAGAAA AACCTTTTGG GTGAAAATTT TAAAACTTAG





10501
AGAGGTCCCA TCAGTTTCCA ACTGCGATGA TCCATTCTCT CCACCACTGC





10551
CCTTGGGCCC AGCCCAATTT AGGTCCACCA TGCCCAGAGG CATGAATTTA





10601
ACTTATGACA CTCTTGTGGT GGAATAATGG CTTTGGGCTT ATGTAGCCAT





10651
GTGTCATTTT TTTAGAGATA CAAATTGAAA TATTTGGGGT GAGATGTCAT





10701
GGTGTCTACT GGCCTCTAAA ACTTCAGTGA AAACATTTAC TTTCACTGAA





10751
ATGTCAATAA ATCATAAATT GGATGTATAT GTTTTAGTTG GAGGAAATAT





10801
AAACCACTAA ATCTAGGTGA TGCATATTTA TTATACTCTT CTCTCTGCTT





10851
TTTTGTACGC TTGTAAAATT GTATTTAAAA GAATAAGACA CACTTGGCCG





10901
GGCGCGGTGG CTCACGCCTG TAATCCCAGC ACTTTGGGAG ACCGAGGTGG





10951
GTGGATCATG AGGTCAGGAG TTCAAGACCA GCCTGGCCAA CATGGTAAAA





11001
CTCCATCACT ACATACAAAA ATTAGCCAGG CATTTTGGCG GGCACCTGTA





11051
ATCTCAGCTA CTTGGGAGGC TGAAGCAGGA GAATTGCTTG AACCCGGGAA





11101
GCAGAGGTTG CAGTGAGCCA AGATCACGCC ACTGCACTCT AGCCTGGGCA





11151
ACAGAGCAAG ACTCCATCTC CAGAAAAAAA AAAAAAAAAA GACACACTCA










Exon C6








11201
CATGCACCCT CCATTTCTTT CATTTCTAGG GTATTCTCCC AACAGAAATG





11251

AGCCCTTAAC TGGGAATTCT GGTAAGTCTC AAAGAAGCCC CAGCCCAGGG






11301
TAGGGAGGGG GTAGCCTGAT GGTGCTTTGC CTTGTCCAAG AGCACCAGGC





11351
ACACAGAGTC TTGGATGAGG ATCAAAATTG CCAACCCATG GCAAAGACTA





11401
TTGAGGCATA GTAAAGGGAT AGCAGGGATC CTGGCTTTCT GGGGGCCCAG





11451
TTTTTGGGGG CATCAGAGGC ATGAGGTGTT GAGCCACTAA GCTCTCTTCC





11501
CCAGGGGCTG TGCCCATCCT CAGGCCACAT AGGGTCCAAG AAGGAGCCCT










Exon C7








11551
GGGACGTGGC AGGAGGTGGC TCACCCCAGC CCTTGTCTCC CCAGACCTTC





11601

CCTTCTGGGC TGTCATCCTC ATCGGCTTGG CAGGACTCCT GGGAGTCATC






11651

ACATGCCTGA TCTGCGGTGT CCTGGTGAGC AAGGAAGGGT TGCTTGTCTT






11701
CTTAACAATT GGGTTGTAAG AGTTCTTAAT ATATTATAAA ACCATACTAT





11751
ACTATACACA AGTCCTTTGC TGGATATATG TTTTGCAAAT ATTTTCTCCC





11801
AGTTCACGGA GTGGCTTTCC TATTTTCTTT TTATAATTTT ATTTTTAATT





11851
AATTGACAAA TAATGAATGC ATATATTTAG GGGATACAAT GTGATGCTTT





11901
GGTATATGTA CAATTATGGA ATGACTCAAT CAAGCTAATT AATATGTCCC





11951
TCACCTCTCA TACTTATTAT TTCTTTGTGG TGTGAACATT GGCAACCTAT





12001
ACTCTTAGCA ATTTTGAAAT CTACATTATT ATTAACTATA GTTACTATGT





12051
TATGCAGATC TCAAAAACTT CACAACCTAT ATGCTGATTA CAAGATATTG





12101
AGAGAAAAAG TGATTGCAAA GAGTGTAAAT AAAATAATGT AAGAGGGAAA





12151
AATGTAACAA AATTAGTCGT TAGGGAAATG TACACGGAAG TCACAATGAG





12201
AGGCCACTTT TCACAAGAAT GGATAAAATT GAAAAGATTG ACTATAACAA





12251
GTGTTGGTGA AAATGTGACA GAACTGGAAC TCTCATAAAG TGAAAGTGGA





12301
AAATAGCTTG GCCATTTCTT TGAAAATTAC ACACACCTAC CGTAAGACCT





12351
ACCATCCCAC TACTAGTAAT TTATCTAAGA GAAATAAAAA CATATGTCTA





12401
TATGAAGACT TGTACACAAG TAAATGTTCA TAACAGCTTT GTTTGTAATA





12451
GCCAAACTCT GAAAACAAGC CCCTAATGTC CATTAACAAA TATATCCTGA





12501
CAATGGAATA TTATTCAGCA ACAAAAAGGA ATTATTAATA CATTAATAAA





12551
TTATACAGCA ACATGTATAA ATTGCAAAAT AGTTATGCCT AGTGAAAGAA





12601
TCCAGATGAA GAAAAGAGTA CATGCCATAT GATTCCCTTA ATAGACAAAT





12651
TCTAGAAAAT ACAAACTAAT CTGTAAGGAC AGGAATCAGA TCAGCGGTTG





12701
CCTGGGAATG AAAATGTGTT TGCAGTGGCA GGGAAAAAGG AATTGTAAAA





12751
GAGCAGGAAG AAAGTTTTTT TGTTGTTTTT TTTTTGTTTT TTCTTGAGAC





12801
AGAGTCTTAG TCTATCGCCC AAGCTGGAGT GCAATGGCAC GATCTCAGCT





12851
CATTGCAACC TCTGCCTCTC GGGTTCAAGC GTTTTTCCTG CCCCAGCCTC





12901
CCAAGTAGCT GGGATTACAC ATGCGCACCA CCACACTCAG CTAATTTTTG





12951
TATTTTTAGT AGAGACGGGG TTTTACCATG TTGGCCAGGC TGGTCTCGAA





13001
CTCCTGACCT CAGGTGATCC ACCCGCCTTG GCCTCCCAAA GTGCTGGGAT





13051
TACAGGAGTG AGCCACCATG CCTGGCCAGG ACGAAAGTTT TGGGGATGAT





13101
GGATGGATGT TCCTTATGTT GATTGTGGTG ACGATTCAAT AAGTTATGAT





13151
CAGAACTTAT CAAAACATTC ACTTTAAATG TGTGCAGTTT ATTTTATGTC





13201
AGTTATGCCT CAGTTAAGCT GGACAGATGT AGAGGAGGAA GGGAGGGAGA





13251
GAGGGGGCTG AGATCAGGAC CAAAAGCCAG AGAGAAAGAG ACTGAGAATG





13301
AGATGAGAGA GAAATGGTAT TTAGACAGAA GACAGGCGAT AGATGATTGA





13351
TAGTTGACAG ATGATTGGTG GATANNNNNN NNNNNNNNNN NNNNNNNNNN





13401
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





13451
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN





13501
AGGAGGTTTA AACAAAACGC AATTATGTTG AAATGACAAT GATTGTGGAT





13551
ATAAAGGTAG ATAGAAATAG ATATTTGTGA AGATAATGGT TAGATAAAAA





13601
TGATAGGTAA CAGATATTGA TAGATCTTGA TAAGTAGATG ATAAATACAT





13651
GATTGATGGA TGACAGGTGA TTGATAGATG ATTTGATGGA TTATAAATAG





13701
GAGATGATTG AGAGGTGAGA GATAATTGAT GGTTATTTGA TTGGTAGATA





13751
ATTGATTGAC AGGTTGATAA ATATTGATAG CTAGATGATA GATAAATAGA





13801
TCATTGGTAG ATATGTGATA TATTGATAAA GAAATTCAGA GGCAAAAGGA





13851
GAGAGAAATG AAGGGGATAT CGGAGGGGGA AAAATTTTTT TAAACCGAGA





13901
GTGAAACAAG GAGACAGAAG AAAAGAAAGT GGTGAAAAGA GGAAAAGAAC





13951
TGAGGGAGAA ATTAAATGAA ACAATGAAGG GAGACAGAGG AAGCATAAGG










Exon C8








14001
CCTCTGGCTT TGGCCATATT CTCACCCCTG TGGTCTCCTC TCCCTGGACG





14051
GCTGACCAGT CCATTCTCAC GCCTCCTCCT CACCCTCATA GGTGACCACC





14101

CGCCGGCGGA AGAAGGAAGG AGAATACAAC GTCCAGCAAC AGTGCCCAGG






14151

CTACTACCAG TCACACCTAG ACCTGGAGGA TCTGCAATGA CTGGAACTTG






14201
CCGGTGCCTG GGGTGCCTTT CCCCCAGCCA GGGTCCAAAG AAGCTTGGCT





14251
GGGGCAGAAA TAAACCATAT TGGTCGG
















TABLE 4





Human cDNA of CA125


(SEQ ID NO: 4)
















1
AAGCGTTGCA CAATTCCCCC AACCTCCATA CATACGGCAG CTCTTCTAGA





51
CACAGGTTTT CCCAGGTCAA ATGCGGGGAC CCCAGCCATA TCTCCCACCC





101
TGAGAAATTT TGGAGTTTCA GGGAGCTCAG AAGCTCTGCA GAGGCCACCC





151
TCTCTGAGGG GATTCTTCTT AGACCTCCAT CCAGAGGCAA ATGTTGACCT





201
GTCCATGCTG AAACCCTCAG GCCTTCCTGG GTCATCTTCT CCCACCCGCT





251
CCTTGATGAC AGGGAGCAGG AGCACTAAAG CCACACCAGA AATGGATTCA





301
GGACTGACAG GAGCCACCTT GTCACCTAAG ACATCTACAG GTGCAATCGT





351
GGTGACAGAA CATACTCTGC CCTTTACTTC CCCAGATAAG ACCTTGGCCA





401
GTCCTACATC TTCGGTTGTG GGAAGAACCA CCCAGTCTTT GGGGGTGATG





451
TCCTCTGCTC TCCCTGAGTC AACCTCTAGA GGAATGACAC ACTCCGAGCA





501
AAGAACCAGC CCATCGCTGA GTCCCCAGGT CAATGGAACT CCCTCTAGGA





551
ACTACCCTGC TACAAGCATG GTTTCAGGAT TGAGTTCCCC AAGGACCAGG





601
ACCAGTTCCA CAGAAGGAAA TTTTACCAAA GAAGCATCTA CATACACACT





651
CACTGTAGAG ACCACAAGTG GCCCAGTCAC TGAGAAGTAC ACAGTCCCCA





701
CTGAGACCTC AACAACTGAA GGTGACAGCA CAGAGACCCC CTGGGACACA





751
AGATATATTC CTGTAAAAAT CACATCTCCA ATGAAAACAT TTGCAGATTC





801
AACTGCATCC AAGGAAAATG CCCCAGTGTC TATGACTCCA GCTGAGACCA





851
CAGTTACTGA CTCACATACT CCAGGAAGGA CAAACCCATC ATTTGGGACA





901
CTTTATTCTT CCTTCCTTGA CCTATCACCT AAAGGGACCC CAAATTCCAG





951
AGGTGAAACA AGCCTGGAAC TGATTCTATC AACCACTGGA TATCCCTTCT





1001
CCTCTCCTGA ACCTGGCTCT GCAGGACACA GCAGAATAAG TACCAGTGCG





1051
CCTTTGTCAT CATCTGCTTC AGTTCTCGAT AATAAAATAT CAGAGACCAG





1101
CATATTCTCA GGCCAGAGTC TCACCTCCCC TCTGTCTCCT GGGGTGCCCG





1151
AGGCCAGAGC CAGCACAATG CCCAACTCAG CTATCCCTTT TTCCATGACA





1201
CTAAGCAATG CAGAAACAAG TGCCGAAAGG GTCAGAAGCA CAATTTCCTC





1251
TCTGGGGACT CCATCAATAT CCACAAAGCA GACAGCAGAG ACTATCCTTA





1301
CCTTCCATGC CTTCGCTGAG ACCATGGATA TACCCAGCAC CCACATAGCC





1351
AAGACTTTGG CTTCAGAATG GTTGGGAAGT CCAGGTACCC TTGGTGGCAC





1401
CAGCACTTCA GCGCTGACAA CCACATCTCC ATCTACCACT TTAGTCTCAG





1451
AGGAGACCAA CACCCATCAC TCCACGAGTG GAAAGGAAAC AGAAGGAACT





1501
TTGAATACAT CTATGACTCC ACTTGAGACC TCTGCTCCTG GAGAAGAGTC





1551
CGAAATGACT GCCACCTTGG TCCCCACTCT AGGTTTTACA ACTCTTGACA





1601
GCAAGATCAG AAGTCCATCT CAGGTCTCTT CATCCCACCC AACAAGAGAG





1651
CTCAGAACCA CAGGCAGCAC CTCTGGGAGG CAGAGTTCCA GCACAGCTGC





1701
CCACGGGAGC TCTGACATCC TGAGGGCAAC CACTTCCAGC ACCTCAAAAG





1751
CATCATCATG GACCAGTGAA AGCACAGCTC AGCAATTTAG TGAACCCCAG





1801
CACACACAGT GGGTGGAGAC AAGTCCTAGC ATGAAAACAG AGAGACCCCC





1851
AGCATCAACC AGTGTGGCAG CCCCTATCAC CACTTCTGTT CCCTCAGTGG





1901
TCTCTGGCTT CACCACCCTG AAGACCAGCT CCACAAAAGG GATTTGGCTT





1951
GAAGAAACAT CTGCAGACAC ACTCATCGGA GAATCCACAG CTGGCCCAAC





2001
CACCCATCAG TTTGCTGTTC CCACTGGGAT TTCAATGACA GGAGGCAGCA





2051
GCACCAGGGG AAGCCAGGGC ACAACCCACC TACTCACCAG AGCCACAGCA





2101
TCATCTGAGA CATCCGCAGA TTTGACTCTG GCCACGAACG GTGTCCCAGT





2151
CTCCGTGTCT CCAGCAGTGA GCAAGACGGC TGCTGGCTCA AGTCCTCCAG





2201
GAGGGACAAA GCCATCATAT ACAATGGTTT CTTCTGTCAT CCCTGAGACA





2251
TCATCTCTAC AGTCCTCAGC TTTCAGGGAA GGAACCAGCC TGGGACTGAC





2301
TCCATTAAAC ACTAGACATC CCTTCTCTTC CCCTGAACCA GACTCTGCAG





2351
GACACACCAA GATAAGCACC AGCATTCCTC TGTTGTCATC TGCTTCAGTT





2401
CTTGAGGATA AAGTGTCAGC GACCAGCACA TTCTCACACC ACAAAGCCAC





2451
CTCATCTATT ACCACAGGGA CTCCTGAAAT CTCAACAAAG ACAAAGCCCA





2501
GCTCAGCCGT TCTTTCCTCC ATGACCCTAA GCAATGCAGC AACAAGTCCT





2551
GAAAGAGTCA GAAATGCAAC TTCCCCTCTG ACTCATCCAT CTCCATCAGG





2601
GGAAGAGACA GCAGGGAGTG TCCTCACTCT CAGCACCTCT GCTGAGACTA





2651
CAGACTCACC TAACATCCAC CCAACTGGGA CACTGACTTC AGAATCGTCA





2701
GAGAGTCCTA GCACTCTCAG CCTCCCAAGT GTCTCTGGAG TCAAAACCAC





2751
ATTTTCTTCA TCTACTCCTT CCACTCATCT ATTTACTAGT GGAGAAGAAA





2801
CAGAGGAAAC TTCGAATCCA TCTGTGTCTC AACCTGAGAC TTCTGTTTCC





2851
AGAGTAAGGA CCACCTTGGC CAGCACCTCT GTCCCTACCC CAGTATTCCC





2901
CACCATGGAC ACCTGGCCTA CACGTTCAGC TCAGTTCTCT TCATCCCACC





2951
TAGTGAGTGA GCTCAGAGCT ACGAGCAGTA CCTCAGTTAC AAACTCAACT





3001
GGTTCAGCTC TTCCTAAAAT ATCTCACCTC ACTGGGACGG CAACAATGTC





3051
ACAGACCAAT AGAGACACGT TTAATGACTC TGCTGCACCC CAAAGCACAA





3101
CTTGGCCAGA GACTAGTCCC AGATTCAAGA CAGGGTTACC TTCAGCAACA





3151
ACCACTGTTT CAACCTCTGC CACTTCTCTC TCTGCTACTG TAATGGTCTC





3201
TAAATTCACT TCTCCAGCAA CTAGTTCCAT GGAAGCAACT TCTATCAGGG





3251
AACCATCAAC AACCATCCTC ACAACAGAGA CCACGAATGG CCCAGGCTCT





3301
ATGGCTGTGG CTTCTACCAA CATCCCAATT GGAAAGGGCT ACATTACTGA





3351
AGGAAGATTG GACACAAGCC ATCTGCCCAT TGGAACCACA GCTTCCTCTG





3401
AGACATCTAT GGATTTTACC ATGGCCAAAG AAAGTGTCTC AATGTCAGTA





3451
TCTCCATCTC AGTCCATGGA TGCTGCTGGC TCAAGCACTC CAGGAAGGAC





3501
AAGCCAATTC GTTGACACAT TTTCTGATGA TGTCTATCAT TTAACATCCA





3551
GAGAAATTAC AATACCTAGA GATGGAACAA GCTCAGCTCT GACTCCACAA





3601
ATGACTGCAA CTCACCCTCC ATCTCCTGAT CCTGGCTCTG CTAGAAGCAC





3651
CTGGCTTGGC ATCTTGTCCT CATCTCCTTC TTCTCCTACT CCCAAAGTCA





3701
CAATGAGCTC CACATTTTCA ACTCAGAGAG TCACCACAAG CATGATAATG





3751
GACACAGTTG AAACTAGTCG GTGGAACATG CCCAACTTAC CTTCCACGAC





3801
TTCCCTGACA CCAAGTAATA TTCCAACAAG TGGTGCCATA GGAAAAAGCA





3851
CCCTGGTTCC CTTGGACACT CCATCTCCAG CCACATCATT GGAGGCATCA





3901
GAAGGGGGAC TTCCAACCCT CAGCACCTAC CCTGAATCAA CAAACACACC





3951
CAGCATCCAC CTCGGAGCAC ACGCTAGTTC AGAAAGTCCA AGCACCATCA





4001
AACTTACCAT GGCTTCAGTA GTAAAACCTG GCTCTTACAC ACCTCTCACC





4051
TTCCCCTCAA TAGAGACCCA CATTCATGTA TCAACAGCCA GAATGGCTTA





4101
CTCTTCTGGG TCTTCACCTG AGATGACAGC TCCTGGAGAG ACTAACACTG





4151
GTAGTACCTG GGACCCCACC ACCTACATCA CCACTACGGA TCCTAAGGAT





4201
ACAAGTTCAG CTCAGGTCTC TACACCCCAC TCAGTGAGGA CACTCAGAAC





4251
CACAGAAAAC CATCCAAAGA CAGAGTCCGC CACCCCAGCT GCTTACTCTG





4301
GAAGTCCTAA AATCTCAAGT TCACCCAATC TCACCAGTCC GGCCACAAAA





4351
GCATGGACCA TCACAGACAC AACTGAACAC TCCACTCAAT TACATTACAC





4401
AAAATTGGCA GAAAAATCAT CTGGATTTGA GACACAGTCA GCTCCAGGAC





4451
CTGTCTCTGT AGTAATCCCT ACCTCCCCTA CCATTGGAAG CAGCACATTG





4501
GAACTAACTT CTGATGTCCC AGGGGAACCC CTGGTCCTTG CTCCCAGTGA





4551
GCAGACCACA ATCACTCTCC CCATGGCAAC ATGGCTGAGT ACCAGTTTGA





4601
CAGAGGAAAT GGCTTCAACA GACCTTGATA TTTCAAGTCC AAGTTCACCC





4651
ATGAGTACAT TTGCTATTTT TCCACCTATG TCCACACCTT CTCATGAACT





4701
TTCAAAGTCA GAGGCAGATA CCAGTGCCAT TAGAAATACA GATTCAACAA





4751
CGTTGGATCA GCACCTAGGA ATCAGGAGTT TGGGCAGAAC TGGGGACTTA





4801
ACAACTGTTC CTATCACCCC ACTGACAACC ACGTGGACCA GTGTGATTGA





4851
ACACTCAACA CAAGCACAGG ACACCCTTTC TGCAACGATG AGTCCTACTC





4901
ACGTGACACA GTCACTCAAA GATCAAACAT CTATACCAGC CTCAGCATCC





4951
CCTTCCCATC TTACTGAAGT CTACCCTGAG CTCGGGACAC AAGGGAGAAG





5001
CTCCTCTGAG GCAACCACTT TTTGGAAACC ATCTACAGAC ACACTGTCCA





5051
GAGAGATTGA GACTGGCCCA ACAAACATTC AATCCACTCC ACCCATGGAC





5101
AACACAACAA CAGGGAGCAG TAGTAGTGGA GTCACCCTGG GCATAGCCCA





5151
CCTTCCCATA GGAACATCCT CCCCAGCTGA GACATCCACA AACATGGCAC





5201
TGGAAAGAAG AAGTTCTACA GCCACTGTCT CTATGGCTGG GACAATGGGA





5251
CTCCTTGTTA CTAGTGCTCC AGGAAGAAGC ATCAGCCAGT CATTAGGAAG





5301
AGTTTCCTCT GTCCTTTCTG AGTCAACTAC TGAAGGAGTC ACAGATTCTA





5351
GTAAGGGAAG CAGCCCAAGG CTGAACACAC AGGGAAATAC AGCTCTCTCC





5401
TCCTCTCTTG AACCCAGCTA TGCTGAAGGA AGCCAGATGA GCACAAGCAT





5451
CCCTCTAACC TCATCTCCTA CAACTCCTGA TGTGGAATTC ATAGGGGGCA





5501
GCACATTTTG GACCAAGGAG GTCACCACAG TTATGACCTC AGACATCTCC





5551
AAGTCTTCAG CAAGGACAGA GTCCAGCTCA GCTACCCTTA TGTCCACAGC





5601
TTTGGGAAGC ACTGAAAATA CAGGAAAAGA AAAACTCAGA ACTGCCTCTA





5651
TGGATCTTCC ATCTCCAACT CCATCAATGG AGGTGACACC ATGGATTTCT





5701
CTCACTCTCA GTAATGCCCC CAATACCACA GATTCACTTG ACCTCAGCCA





5751
TGGGGTGCAC ACCAGCTCTG CAGGGACTTT GGCCACTGAC AGGTCATTGA





5801
ATACTGGTGT CACTAGAGCC TCCAGATTGG AAAACGGCTC TGATACCTCT





5851
TCTAAGTCCC TGTCTATGGG AAACAGCACT CACACTTCCA TGACTGACAC





5901
AGAGAAGAGT GAAGTGTCTT CTTCAATCCA TCCCCGACCT GAGACCTCAG





5951
CTCCTGGAGC AGAGACCACT TTGACTTCCA CTCCTGGAAA CAGGGCCATA





6001
AGCTTAACAT TGCCTTTTTC ATCCATTCCA GTGGAAGAAG TCATTTCTAC





6051
AGGCATAACC TCAGGACCAG ACATCAACTC AGCACCCATG ACACATTCTC





6101
CCATCACCCC ACCAACAATT GTATGGACCA GTACAGGCAC AATTGAACAG





6151
TCCACTCAAC CACTACATGC AGTTTCTTCA GAAAAAGTTT CTGTGCAGAC





6201
ACAGTCAACT CCATATGTCA ACTCTGTGGC AGTGTCTGCT TCCCCTACCC





6251
ATGAGAATTC AGTCTCTTCT GGAAGCAGCA CATCCTCTCC ATATTCCTCA





6301
GCCTCACTTG AATCCTTGGA TTCCACAATC AGTAGGAGGA ATGCAATCAC





6351
TTCCTGGCTA TGGGACCTCA CTACATCTCT CCCCACTACA ACTTGGCCAA





6401
GTACTAGTTT ATCTGAGGCA CTGTCCTCAG GCCATTCTGG GGTTTCAAAC





6451
CCAAGTTCAA CTACGACTGA ATTTCCACTC TTTTCAGCTG CATCCACATC





6501
TGCTGCTAAG CAAAGAAATC CAGAAACAGA GACCCATGGT CCCCAGAATA





6551
CAGCCGCGAG TACTTTGAAC ACTGATGCAT CCTCGGTCAC AGGTCTTTCT





6601
GAGACTCCTG TGGGGGCAAG TATCAGCTCT GAAGTCCCTC TTCCAATGGC





6651
CATAACTTCT AGATCAGATG TTTCTGGCCT TACATCTGAG AGTACTGCTA





6701
ACCCGAGTTT AGGCACAGCC TCTTCAGCAG GGACCAAATT AACTAGGACA





6751
ATATCCCTGC CCACTTCAGA GTCTTTGGTT TCCTTTAGAA TGAACAAGGA





6801
TCCATGGACA GTGTCAATCC CTTTGGGGTC CCATCCAACT ACTAATACAG





6851
AAACAAGCAT CCCAGTAAAC AGCGCAGGTC CACCTGGCTT GTCCACAGTA





6901
GCATCAGATG TAATTGACAC ACCTTCAGAT GGGGCTGAGA GTATTCCCAC





6951
TGTCTCCTTT TCCCCCTCCC CTGATACTGA AGTGACAACT ATCTCACATT





7001
TCCCAGAAAA GACAACTCAT TCATTTAGAA CCATTTCATC TCTCACTCAT





7051
GAGTTGACTT CAAGAGTGAC ACCTATTCCT GGGGATTGGA TGAGTTCAGC





7101
TATGTCTACA AAGCCCACAG GAGCCAGTCC CTCCATTACA CTGGGAGAGA





7151
GAAGGACAAT CACCTCTGCT GCTCCAACCA CTTCCCCCAT AGTTCTCACT





7201
GCTAGTTTCA CAGAGACCAG CACAGTTTCA CTGGATAATG AAACTACAGT





7251
AAAAACCTCA GATATCCTTG ACGCACGGAA AACAAATGAG CTCCCCTCAG





7301
ATAGCAGTTC TTCTTCTGAT CTGATCAACA CCTCCATAGC TTCTTCAACT





7351
ATGGATGTCA CTAAAACAGC CTCCATCAGT CCCACTAGCA TCTCAGGAAT





7401
GACAGCAAGT TCCTCCCCAT CTCTCTTCTC TTCAGATAGA CCCCAGGTTC





7451
CCACATCTAC AACAGAGACA AATACAGCCA CCTCTCCATC TGTTTCCAGT





7501
AACACCTATT CTCTTGATGG GGGCTCCAAT GTGGGTGGCA CTCCATCCAC





7551
TTTACCACCC TTTACAATCA CCCACCCTGT CGAGACAAGC TCGGCCCTAT





7601
TAGCCTGGTC TAGACCAGTA AGAACTTTCA GCACCATGGT CAGCACTGAC





7651
ACTGCCTCCG GAGAAAATCC TACCTCTAGC AATTCTGTGG TGACTTCTGT





7701
TCCAGCACCA GGTACATGGG CCAGTGTAGG CAGTACTACT GACTTACCTG





7751
CCATGGGCTT TCTCAAGACA AGTCCTGCAG GAGAGGCACA CTCACTTCTA





7801
GCATCAACTA TTGAACCAGC CACTGCCTTC ACTCCCCATC TCTCAGCAGC





7851
AGTGGTCACT GGATCCAGTG CTACATCAGA AGCCAGTCTT CTCACTACGA





7901
GTGAAAGCAA AGCCATTCAT TCTTCACCAC AGACCCCAAC TACACCCACC





7951
TCTGGAGCAA ACTGGGAAAC TTCAGCTACT CCTGAGAGCC TTTTGGTAGT





8001
CACTGAGACT TCAGACACAA CACTTACCTC AAAGATTTTG GTCACAGATA





8051
CCATCTTGTT TTCAACTGTG TCCACGCCAC CTTCTAAATT TCCAAGTACG





8101
GGGACTCTGT CTGGAGCTTC CTTCCCTACT TTACTCCCGG ACACTCCAGC





8151
CATCCCTCTC ACTGCCACTG AGCCAACAAG TTCATTAGCT ACATCCTTTG





8201
ATTCCACCCC ACTGGTGACT ATAGCTTCGG ATAGTCTTGG CACAGTCCCA





8251
GAGACTACCC TGACCATGTC AGAGACCTCA AATGGTGATG CACTGGTTCT





8301
TAAGACAGTA AGTAACCCAG ATAGGAGCAT CCCTGGAATC ACTATCCAAG





8351
GAGTAACAGA AAGTCCACTC CATCCTTCTT CCACTTCCCC CTCTAAGATT





8401
GTTGCTCCAC GGAATACAAC CTATGAAGGT TCGATCACAG TGGCACTTTC





8451
TACTTTGCCT GCGGGAACTA CTGGTTCCCT TGTATTCAGT CAGAGTTCTG





8501
AAAACTCAGA GACAACGGCT TTGGTAGACT CATCAGCTGG GCTTGAGAGG





8551
GCATCTGTGA TGCCACTAAC CACAGGAAGC CAGGGTATGG CTAGCTCTGG





8601
AGGAATCAGA AGTGGGTCCA CTCACTCAAC TGGAACCAAA ACATTTTCTT





8651
CTCTCCCTCT GACCATGAAC CCAGGTGAGG TTACAGCCAT GTCTGAAATC





8701
ACCACGAACA GACTGACAGC TACTCAATCA ACAGCACCCA AAGGGATACC





8751
TGTGAAGCCC ACCAGTGCTG AGTCAGGCCT CCTAACACCT GTCTCTGCCT





8801
CCTCAAGCCC ATCAAAGGCC TTTGCCTCAC TGACTACAGC TCCCCCATCA





8851
ACTTGGGGGA TCCCACAGTC TACCTTGACA TTTGAGTTTT CTGAGGTCCC





8901
AAGTTTGGAT ACTAAGTCCG CTTCTTTACC AACTCCTGGA CAGTCCCTGA





8951
ACACCATTCC AGACTCAGAT GCAAGCACAG CATCTTCCTC ACTGTCCAAG





9001
TCTCCAGAAA AAAACCCAAG GGCAAGGATG ATGACTTCCA CAAAGGCCAT





9051
AAGTGCAAGC TCATTTCAAT CAACAGGTTT TACTGAAACC CCTGAGGGAT





9101
CTGCCTCCCC TTCTATGGCA GGGCATGAAC CCAGAGTCCC CACTTCAGGA





9151
ACAGGGGACC CTAGATATGC CTCAGAGAGC ATGTCTTATC CAGACCCAAG





9201
CAAGGCATCA TCAGCTATGA CATCGACCTC TCTTGCATCA AAACTCACAA





9251
CTCTCTTCAG CACAGGTCAA GCAGCAAGGT CTGGTTCTAG TTCCTCTCCC





9301
ATAAGCCTAT CCACTGAGAA AGAAACAAGC TTCCTTTCCC CCACTGCATC





9351
CACCTCCAGA AAGACTTCAC TATTTCTTGG GCCTTCCATG GCAAGGCAGC





9401
CCAACATATT GGTGCATCTT CAGACTTCAG CTCTGACACT TTCTCCAACA





9451
TCCACTCTAA ATATGTCCCA GGAGGAGCCT CCTGAGTTAA CCTCAAGCCA





9501
GACCATTGCA GAAGAAGAGG GAACAACAGC TGAAACACAG ACGTTAACCT





9551
TCACACCATC TGAGACCCCA ACATCCTTGT TACCTGTCTC TTCTCCCACA





9601
GAACCCACAG CCAGAAGAAA GAGTTCTCCA GAAACATGGG CAAGCTCTAT





9651
TTCAGTTCCT GCCAAGACCT CCTTGGTTGA AACAACTGAT GGAACGCTAG





9701
TGACCACCAT AAAGATGTCA AGCCAGGCAG CACAAGGAAA TTCCACGTGG





9751
CCTGCCCCAG CAGAGGAGAC GGGGACCAGT CCAGCAGGCA CATCCCCAGG





9801
AAGCCCAGAA GTGTCTACCA CTCTCAAAAT CATGAGCTCC AAGGAACCCA





9851
GCATCAGCCC AGAGATCAGG TCCACTGTGC GAAATTCTCC TTGGAAGACT





9901
CCAGAAACAA CTGTTCCCAT GGAGACCACA GTGGAACCAG TCACCCTTCA





9951
GTCCACAGCC CTAGGAAGTG GCAGCACCAG CATCTCTCAC CTGCCCACAG





10001
GAACCACATC ACCAACCAAG TCACCAACAG AAAATATGTT GGCTACAGAA





10051
AGGGTCTCCC TCTCCCCATC CCCACCTGAG GCTTGGACCA ACCTTTATTC





10101
TGGAACTCCA GGAGGGACCA GGCAGTCACT GGCCACAATG TCCTCTGTCT





10151
CCCTAGAGTC ACCAACTGCT AGAAGCATCA CAGGGACTGG TCAGCAAAGC





10201
AGTCCAGAAC TGGTTTCAAA GACAACTGGA ATGGAATTCT CTATGTGGCA





10251
TGGCTCTACT GGAGGGACCA CAGGGGACAC ACATGTCTCT CTGAGCACAT





10301
CTTCCAATAT CCTTGAAGAC CCTGTAACCA GCCCAAACTC TGTGAGCTCA





10351
TTGACAGATA AATCCAAACA TAAAACCGAG ACATGGGTAA GCACCACAGC





10401
CATTCCCTCC ACTGTCCTGA ATAATAAGAT AATGGCAGCT GAACAACAGA





10451
CAAGTCGATC TGTGGATGAG GCTTATTCAT CAACTAGTTC TTGGTCAGAT





10501
CAGACATCTG GGAGTGACAT CACCCTTGGT GCATCTCCTG ATGTCACAAA





10551
CACATTATAC ATCACCTCCA CAGCACAAAC CACCTCACTA GTGTCTCTGC





10601
CCTCTGGAGA CCAAGGCATT ACAAGCCTCA CCAATCCCTC AGGAGGAAAA





10651
ACAAGCTCTG CGTCATCTGT CACATCTCCT TCAATAGGGC TTGAGACTCT





10701
GAGGGCCAAT GTAAGTGCAG TGAAAAGTGA CATTGCCCCT ACTGCTGGGC





10751
ATCTATCTCA GACTTCATCT CCTGCGGAAG TGAGCATCCT GGACGTAACC





10801
ACAGCTCCTA CTCCAGGTAT CTCCACCACC ATCACCACCA TGGGAACCAA





10851
CTCAATCTCA ACTACCACAC CCAACCCAGA AGTGGGTATG AGTACCATGG





10901
ACAGCACCCC GGCCACAGAG AGGCGCACAA CTTCTACAGA ACACCCTTCC





10951
ACCTGGTCTT CCACAGCTGC ATCAGATTCC TGGACTGTCA CAGACATGAC





11001
TTCAAACTTG AAAGTTGCAA GATCTCCTGG AACAATTTCC ACAATGCATA





11051
CAACTTCATT CTTAGCCTCA AGCACTGAAT TAGACTCCAT GTCTACTCCC





11101
CATGGCCGTA TAACTGTCAT TGGAACCAGC CTGGTCACTC CATCCTCTGA





11151
TGCTTCAGCT GTAAAGACAG AGACCAGTAC AAGTGAAAGA ACATTGAGTC





11201
CTTCAGACAC AACTGCATCT ACTCCCATCT CAACTTTTTC TCGTGTCCAG





11251
AGGATGAGCA TCTCAGTTCC TGACATTTTA AGTACAAGTT GGACTCCCAG





11301
TAGTACAGAA GCAGAAGATG TGCCTGTTTC AATGGTTTCT ACAGATCATG





11351
CTAGTACAAA GACTGACCCA AATACGCCCC TGTCCACTTT TCTGTTTGAT





11401
TCTCTGTCCA CTCTTGACTG GGACACTGGG AGATCTCTGT CATCAGCCAC





11451
AGCCACTACC TCAGCTCCTC AGGGGGCCAC AACTCCCCAG GAACTCACTT





11501
TGGAAACCAT GATCAGCCCA GCTACCTCAC AGTTGCCCTT CTCTATAGGG





11551
CACATTACAA GTGCAGTCAC ACCAGCTGCA ATGGCAAGGA GCTCTGGAGT





11601
TACTTTTTCA AGACCAGATC CCACAAGCAA AAAGGCAGAG CAGACTTCCA





11651
CTCAGCTTCC CACCACCACT TCTGCACATC CAGGGCAGGT GCCCAGATCA





11701
GCAGCAACAA CTCTGGATGT GATCCCACAC ACAGCAAAAA CTCCAGATGC





11751
AACTTTTCAG AGACAAGGGC AGACAGCTCT TACAACAGAG GCAAGAGCTA





11801
CATCTGACTC CTGGAATGAG AAAGAAAAAT CAACCCCAAG TGCACCTTGG





11851
ATCACTGAGA TGATGAATTC TGTCTCAGAA GATACCATCA AGGAGGTTAC





11901
CAGCTCCTCC AGTGTATTAA AGGACCCTGA ATACGCTGGA CATAAACTTG





11951
GAATCTGGGA CGACTTCATC CCCAAGTTTG GAAAAGCAGC CCATATGAGA





12001
GAGTTGCCCC TTCTGAGTCC ACCACAGGAC AAAGAGGCAA TTCACCCTTC





12051
TACAAACACA GTAGAGACCA CAGGCTGGGT CACAAGTTCC GAACATGCTT





12101
CTCATTCCAC TATCCCAGCC CACTCAGCGT CATCCAAACT CACATCTCCA





12151
GTGGTTACAA CCTCCACCAG GGAACAAGCA ATAGTTTCTA TGTCAACAAC





12201
CACATGGCCA GAGTCTACAA GGGCTAGAAC AGAGCCTAAT TCCTTCTTGA





12251
CTATTGAACT GAGGGACGTC AGCCCTTACA TGGACACCAG CTCAACCACA





12301
CAAACAAGTA TTATCTCTTC CCCAGGTTCC ACTGCGATCA CCAAGGGGCC





12351
TAGAACAGAA ATTACCTCCT CTAAGAGAAT ATCCAGCTCA TTCCTTGCCC





12401
AGTCTATGAG GTCGTCAGAC AGCCCCTCAG AAGCCATCAC CAGGCTGTCT





12451
AACTTTCCTG CCATGACAGA ATCTGGAGGA ATGATCCTTG CTATGCAAAC





12501
AAGTCCACCT GGCGCTACAT CACTAAGTGC ACCTACTTTG GATACATCAG





12551
CCACAGCCTC CTGGACAGGG ACTCCACTGG CTACGACTCA GAGATTTACA





12601
TACTCAGAGA AGACCACTCT CTTTAGCAAA GGTCCTGAGG ATACATCACA





12651
GCCAAGCCCT CCCTCTGTGG AAGAAACCAG CTCTTCCTCT TCCCTGGTAC





12701
CTATCCATGC TACAACCTCG CCTTCCAATA TTTTGTTGAC ATCACAAGGG





12751
CACAGTCCCT CCTCTACTCC ACCTGTGACC TCAGTTTTCT TGTCTGAGAC





12801
CTCTGGCCTG GGGAAGACCA CAGACATGTC GAGGATAAGC TTGGAACCTG





12851
GCACAAGTTT ACCTCCCAAT TTGAGCAGTA CAGCAGGTGA GGCGTTATCC





12901
ACTTATGAAG CCTCCAGAGA TACAAAGGCA ATTCATCATT CTGCAGACAC





12951
AGCAGTGACG AATATGGAGG CAACCAGTTC TGAATATTCT CCTATCCCAG





13001
GCCATACAAA GCCATCCAAA GCCACATCTC CATTGGTTAC CTCCCACATC





13051
ATGGGGGACA TCACTTCTTC CACATCAGTA TTTGGCTCCT CCGAGACCAC





13101
AGAGATTGAG ACAGTGTCCT CTGTGAACCA GGGACTTCAG GAGAGAAGCA





13151
CATCCCAGGT GGCCAGCTCT GCTACAGAGA CAAGCACTGT CATTACCCAT





13201
GTGTCTAGTG GTGATGCTAC TACTCATGTC ACCAAGACAC AAGCCACTTT





13251
CTCTAGCGGA ACATCCATCT CAAGCCCTCA TCAGTTTATA ACTTCTACCA





13301
ACACATTTAC AGATGTGAGC ACCAACCCCT CCACCTCTCT GATAATGACA





13351
GAATCTTCAG GAGTGACCAT CACCACCCAA ACAGGTCCTA CTGGAGCTGC





13401
AACACAGGGT CCATATCTCT TGGACACATC AACCATGCCT TACTTGACAG





13451
AGACTCCATT AGCTGTGACT CCAGATTTTA TGCAATCAGA GAAGACCACT





13501
CTCATAAGCA AAGGTCCCAA GGATGTGACC TGGACAAGCC CTCCCTCTGT





13551
GGCAGAAACC AGCTATCCCT CTTCCCTGAC ACCTTTCTTG GTCACAACCA





13601
TACCTCCTGC CACTTCCACG TTACAAGGGC AACATACATC CTCTCCTGTT





13651
TCTGCGACTT CAGTTCTTAC CTCTGGACTG GTGAAGACCA CAGATATGTT





13701
GAACACAAGC ATGGAACCTG TGACCAATTC ACCTCAAAAT TTGAACAATC





13751
CATCAAATGA GATACTGGCC ACTTTGGCAG CCACCACAGA TATAGAGACT





13801
ATTCATCCTT CCATAAACAA AGCAGTGACC AATATGGGGA CTGCCAGTTC





13851
AGCACATGTA CTGCATTCCA CTCTCCCAGT CAGCTCAGAA CCATCTACAG





13901
CCACATCTCC AATGGTTCCT GCCTCCAGCA TGGGGGACGC TCTTGCTTCT





13951
ATATCAATAC CTGGTTCTGA GACCACAGAC ATTGAGGGAG AGCCAACATC





14001
CTCCCTGACT GCTGGACGAA AAGAGAACAG CACCCTCCAG GAGATGAACT





14051
CAACTACAGA GTCAAACATC ATCCTCTCCA ATGTGTCTGT GGGGGCTATT





14101
ACTGAAGCCA CAAAAATGGA AGTCCCCTCT TTTGATGCAA CATTCATACC





14151
AACTCCTGCT CAGTCAACAA AGTTCCCAGA TATTTTCTCA GTAGCCAGCA





14201
GTAGACTTTC AAACTCTCCT CCCATGACAA TATCTACCCA CATGACCACC





14251
ACCCAGACAG GGTCTTCTGG AGCTACATCA AAGATTCCAC TTGCCTTAGA





14301
CACATCAACC TTGGAAACCT CAGCAGGGAC TCCATCAGTG GTGACTGAGG





14351
GGTTTGCCCA CTCAAAAATA ACCACTGCAA TGAACAATGA TGTCAAGGAC





14401
GTGTCACAGA CAAACCCTCC CTTTCAGGAT GAAGCCAGCT CTCCCTCTTC





14451
TCAAGCACCT GTCCTTGTCA CAACCTTACC TTCTTCTGTT GCTTTCACAC





14501
CGCAATGGCA CAGTACCTCC TCTCCTGTTT CTATGTCCTC AGTTCTTACT





14551
TCTTCACTGG TAAAGACCGC AGGCAAGGTG GATACAAGCT TAGAAACAGT





14601
GACCAGTTCA CCTCAAAGTA TGAGCAACAC TTTGGATGAC ATATCGGTCA





14651
CTTCAGCAGC CACCACAGAT ATAGAGACAA CGCATCCTTC CATAAACACA





14701
GTAGTTACCA ATGTGGGGAC CACCGGTTCA GCATTTGAAT CACATTCTAC





14751
TGTCTCAGCT TACCCAGAGC CATCTAAAGT CACATCTCCA AATGTTACCA





14801
CCTCCACCAT GGAAGACACC ACAATTTCCC GATCAATACC TAAATCCTCT





14851
AAGACTACAA GAACTGAGAC TGAGACAACT TCCTCCCTGA CTCCTAAACT





14901
GAGGGAGACC AGCATCTCCC AGGAGATCAC CTCGTCCACA GAGACAAGCA





14951
CTGTTCCTTA CAAAGAGCTC ACTGGTGCCA CTACCGAGGT ATCCAGGACA





15001
GATGTCACTT CCTCTAGCAG TACATCCTTC CCTGGCCCTG ATCAGTCCAC





15051
AGTGTCACTA GACATCTCCA CAGAAACCAA CACCAGGCTG TCTACCTCCC





15101
CAATAATGAC AGAATCTGCA GAAATAACCA TCACCACCCA AACAGGTCCT





15151
CATGGGGCTA CATCACAGGA TACTTTTACC ATGGACCCAT CAAATACAAC





15201
CCCCCAGGCA GGGATCCACT CAGCTATGAC TCATGGATTT TCACAATTGG





15251
ATGTGACCAC TCTTATGAGC AGAATTCCAC AGGATGTATC ATGGACAAGT





15301
CCTCCCTCTG TGGATAAAAC CAGCTCCCCC TCTTCCTTTC TGTCCTCACC





15351
TGCAATGACC ACACCTTCCC TGATTTCTTC TACCTTACCA GAGGATAAGC





15401
TCTCCTCTCC TATGACTTCA CTTCTCACCT CTGGCCTAGT GAAGATTACA





15451
GACATATTAC GTACACGCTT GGAACCTGTG ACCAGCTCAC TTCCAAATTT





15501
CAGCAGCACC TCAGATAAGA TACTGGCCAC TTCTAAAGAC AGTAAAGACA





15551
CAAAGGAAAT TTTTCCTTCT ATAAACACAG AAGAGACCAA TGTGAAAGCC





15601
AACAACTCTG GACATGAATC CCATTCCCCT GCACTGGCTG ACTCAGAGAC





15651
ACCCAAAGCC ACAACTCAAA TGGTTATCAC CACCACTGTG GGAGATCCAG





15701
CTCCTTCCAC ATCAATGCCA GTGCATGGTT CCTCTGAGAC TACAAACATT





15751
AAGAGAGAGC CAACATATTT CTTGACTCCT AGACTGAGAG AGACCAGTAC





15801
CTCTCAGGAG TCCAGCTTTC CCACGGACAC AAGTTTTCTA CTTTCCAAAG





15851
TCCCCACTGG TACTATTACT GAGGTCTCCA GTACAGGGGT CAACTCTTCT





15901
AGCAAAATTT CCACCCCAGA CCATGATAAG TCCACAGTGC CACCTGACAC





15951
CTTCACAGGA GAGATCCCCA GGGTCTTCAC CTCCTCTATT AAGACAAAAT





16001
CTGCAGAAAT GACGATCACC ACCCAAGCAA GTCCTCCTGA GTCTGCATCG





16051
CACAGTACCC TTCCCTTGGA CACATCAACC ACACTTTCCC AGGGAGGGAC





16101
TCATTCAACT GTGACTCAGG GATTCCCATA CTCAGAGGTG ACCACTCTCA





16151
TGGGCATGGG TCCTGGGAAT GTGTCATGGA TGACAACTCC CCCTGTGGAA





16201
GAAACCAGCT CTGTGTCTTC CCTGATGTCT TCACCTGCCA TGACATCCCC





16251
TTCTCCTGTT TCCTCCACAT CACCACAGAG CATCCCCTCC TCTCCTCTTC





16301
CTGTGACTGC ACTTCCTACT TCTGTTCTGG TGACAACCAC AGATGTGTTG





16351
GGCACAACAA GCCCAGAGTC TGTAACCAGT TCACCTCCAA ATTTGAGCAG





16401
CATCACTCAT GAGAGACCGG CCACTTACAA AGACACTGCA CACACAGAAG





16451
CCGCCATGCA TCATTCCACA AACACCGCAG TGACCAATGT AGGGACTTCC





16501
GGGTCTGGAC ATAAATCACA ATCCTCTGTC CTAGCTGACT CAGAGACATC





16551
GAAAGCCACA CCTCTGATGA GTACCACCTC CACCCTGGGG GACACAAGTG





16601
TTTCCACATC AACTCCTAAT ATCTCTCAGA CTAACCAAAT TCAAACAGAG





16651
CCAACAGCAT CCCTGAGCCC TAGACTGAGG GAGAGCAGCA CGTCTGAGAA





16701
GACCAGCTCA ACAACAGAGA CAAATACTGC CTTTTCTTAT GTGCCCACAG





16751
GTGCTATTAC TCAGGCCTCC AGAACAGAAA TCTCCTCTAG CAGAACATCC





16801
ATCTCAGACC TTGATCGGCC CACAATAGCA CCCGACATCT CCACAGGAAT





16851
GATCACCAGG CTCTTCACCT CCCCCATCAT GACAAAATCT GCAGAAATGA





16901
CCGTCACCAC TCAAACAACT ACTCCTGGGG CTACATCACA GGGTATCCTT





16951
CCTTGGGACA CATCAACCAC ACTTTTCCAG GGAGGGACTC ATTCAACCGT





17001
GTCTCAGGGA TTCCCACACT CAGAGATAAC CACTCTTCGG AGCAGAACCC





17051
CTGGAGATGT GTCATGGATG ACAACTCCCC CTGTGGAAGA AACCAGCTCT





17101
GGGTTTTCCC TGATGTCACC TTCCATGACA TCCCCTTCTC CTGTTTCCTC





17151
CACATCACCA GAGAGCATCC CCTCCTCTCC TCTCCCTGTG ACTGCACTTC





17201
TTACTTCTGT TCTGGTGACA ACCACCAATG TATTGGGCAC AACAAGCCCA





17251
GAGACCGTAA CGAGTTCACC TCCAAATTTA AGCAGCCCCA CACAGGAGAG





17301
ACTGACCACT TACAAAGACA CTGCGCACAC AGAAGCCATG CATGCTTCCA





17351
TGCATACAAA CACTGCAGTG GCCAACGTCG GGACCTCCAT TTCTGGACAT





17401
GAATCACAAT CTTCTGTCCC AGCTGATTCA CACACATCCA AAGCCACATC





17451
TCCAATGGGT ATCACCTTCG CCATGGGGGA TACAAGTGTT TCTACATCAA





17501
CTCCTGCCTT CTTTGAGACT AGAATTCAGA CTGAATCAAC ATCCTCTTTG





17551
ATTCCTGGAT TAAGGGACAC CAGGACGTCT GAGGAGATCA ACACTGTGAC





17601
AGAGACCAGC ACTGTCCTTT CAGAAGTGCC CACTACTACT ACTACTGAGG





17651
TCTCCAGGAC AGAAGTTATC ACTTCCAGCA GAACAACCAT CTCAGGGCCT





17701
GATCATTCCA AAATGTCACC CTACATCTCC ACAGAAACCA TCACCAGGCT





17751
CTCCACTTTT CCTTTTGTAA CAGGATCCAC AGAAATGGCC ATCACCAACC





17801
AAACAGGTCC TATAGGGACT ATCTCACAGG CTACCCTTAC CCTGGACACA





17851
TCAAGCACAG CTTCCTGGGA AGGGACTCAC TCACCTGTGA CTCAGAGATT





17901
TCCACACTCA GAGGAGACCA CTACTATGAG CAGAAGTACT AAGGGCGTGT





17951
CATGGCAAAG CCCTCCCTCT GTGGAAGAAA CCAGTTCTCC TTCTTCCCCA





18001
GTGCCTTTAC CTGCAATAAC CTCACATTCA TCTCTTTATT CCGCAGTATC





18051
AGGAAGTAGC CCCACTTCTG CTCTCCCTGT GACTTCCCTT CTCACCTCTG





18101
GCAGGAGGAA GACCATAGAC ATGTTGGACA CACACTCAGA ACTTGTGACC





18151
AGCTCCTTAC CAAGTGCAAG TAGCTTCTCA GGTGAGATAC TCACTTCTGA





18201
AGCCTCCACA AATACAGAGA CAATTCACTT TTCAGAGAAC ACAGCAGAAA





18251
CCAATATGGG GACCACCAAT TCTATGCATA AACTACATTC CTCTGTCTCA





18301
ATCCACTCCC AGCCATCCGG ACACACACCT CCAAAGGTTA CTGGATCTAT





18351
GATGGAGGAC GCTATTGTTT CCACATCAAC ACCTGGTTCT CCTGAGACTA





18401
AAAATGTTGA CAGAGACTCA ACATCCCCTC TGACTCCTGA ACTGAAAGAG





18451
GACAGCACCG CCCTGGTGAT GAACTCAACT ACAGAGTCAA ACACTGTTTT





18501
CTCCAGTGTG TCCCTGGATG CTGCTACTGA GGTCTCCAGG GCAGAAGTCA





18551
CCTACTATGA TCCTACATTC ATGCCAGCTT CTGCTCAGTC AACAAAGTCC





18601
CCAGACATTT CACCTGAAGC CAGCAGCAGT CATTCTAACT CTCCTCCCTT





18651
GACAATATCT ACACACAAGA CCATCGCCAC ACAAACAGGT CCTTCTGGGG





18701
TGACATCTCT TGGCCAACTG ACCCTGGACA CATCAACCAT AGCCACCTCA





18751
GCAGGAACTC CATCAGCCAG AACTCAGGAT TTTGTAGATT CAGAAACAAC





18801
CAGTGTCATG AACAATGATC TCAATGATGT GTTGAAGACA AGCCCTTTCT





18851
CTGCAGAAGA AGCCAACTCT CTCTCTTCTC AGGCACCTCT CCTTGTGACA





18901
ACCTCACCTT CTCCTGTAAC TTCCACATTG CAAGAGCACA GTACCTCCTC





18951
TCTTGTTTCT GTGACCTCAG TACCCACCCC TACACTGGCG AAGATCACAG





19001
ACATGGACAC AAACTTAGAA CCTGTGACTC GTTCACCTCA AAATTTAAGG





19051
AACACCTTGG CCACTTCAGA AGCCACCACA GATACACACA CAATGCATCC





19101
TTCTATAAAC ACAGCAATGG CCAATGTGGG GACCACCAGT TCACCAAATG





19151
AATTCTATTT TACTGTCTCA CCTGACTCAG ACCCATATAA AGCCACATCC





19201
GCAGTAGTTA TCACTTCCAC CTCGGGGGAC TCAATAGTTT CCACATCAAT





19251
GCCTAGATCC TCTGCGATGA AAAAGATTGA GTCTGAGACA ACTTTCTCCC





19301
TGATATTTAG ACTGAGGGAG ACTAGCACCT CCCAGAAAAT TGGCTCATCC





19351
TCAGACACAA GCACGGTCTT TGACAAAGCA TTCACTGCTG CTACTACTGA





19401
GGTCTCCAGA ACAGAACTCA CCTCCTCTAG CAGAACATCC ATCCAAGGCA





19451
CTGAAAAGCC CACAATGTCA CCGGACACCT CCACAAGATC TGTCACCATG





19501
CTTTCTACTT TTGCTGGCCT GACAAAATCC GAAGAAAGGA CCATTGCCAC





19551
CCAAACAGGT CCTCATAGGG CGACATCACA GGGTACCCTT ACCTGGGACA





19601
CATCAATCAC AACCTCACAG GCAGGGACCC ACTCAGCTAT GACTCATGGA





19651
TTTTCACAAT TAGATTTGTC CACTCTTACG AGTAGAGTTC CTGAGTACAT





19701
ATCAGGGACA AGCCCACCCT CTGTGGAAAA AACCAGCTCT TCCTCTTCCC





19751
TTCTGTCTTT ACCAGCAATA ACCTCACCGT CCCCTGTACC TACTACATTA





19801
CCAGAAAGTA GGCCGTCTTC TCCTGTTCAT CTGACTTCAC TCCCCACCTC





19851
TGGCCTAGTG AAGACCACAG ATATGCTGGC ATCTGTGGCC AGTTTACCTC





19901
CAAACTTGGG CAGCACCTCA CATAAGATAC CGACTACTTC AGAAGACATT





19951
AAAGATACAG AGAAAATGTA TCCTTCCACA AACATAGCAG TAACCAATGT





20001
GGGGACCACC ACTTCTGAAA AGGAATCTTA TTCGTCTGTC CCAGCCTACT





20051
CAGAACCACC CAAAGTCACC TCTCCAATGG TTACCTCTTT CAACATAAGG





20101
GACACCATTG TTTCCACATC CATGCCTGGC TCCTCTGAGA TTACAAGGAT





20151
TGAGATGGAG TCAACATTCT CCGTGGCTCA TGGGCTGAAG GGAACCAGCA





20201
CCTCCCAGGA CCCCATCGTA TCCACAGAGA AAAGTGCTGT CCTTCACAAG





20251
TTGACCACTG GTGCTACTGA GACCTCTAGG ACAGAAGTTG CCTCTTCTAG





20301
AAGAACATCC ATTCCAGGCC CTGATCATTC CACAGAGTCA CCAGACATCT





20351
CCACTGAAGT GATCCCCAGC CTGCCTATCT CCCTTGGCAT TACAGAATCT





20401
TCAAATATGA CCATCATCAC TCGAACAGGT CCTCCTCTTG GCTCTACATC





20451
ACAGGGCACA TTTACCTTGG ACACACCAAC TACATCCTCC AGGGCAGGAA





20501
CACACTCGAT GGCGACTCAG GAATTTCCAC ACTCAGAAAT GACCACTGTC





20551
ATGAACAAGG ACCCTGAGAT TCTATCATGG ACAATCCCTC CTTCTATAGA





20601
GAAAACCAGC TTCTCCTCTT CCCTGATGCC TTCACCAGCC ATGACTTCAC





20651
CTCCTGTTTC CTCAACATTA CCAAAGACCA TTCACACCAC TCCTTCTCCT





20701
ATGACCTCAC TGCTCACCCC TAGCCTAGTG ATGACCACAG ACACATTGGG





20751
CACAAGCCCA GAACCTACAA CCAGTTCACC TCCAAATTTG AGCAGTACCT





20801
CACATGTGAT ACTGACAACA GATGAAGACA CCACAGCTAT AGAAGCCATG





20851
CATCCTTCCA CAAGCACAGC AGCGACTAAT GTGGAAACCA CCTGTTCTGG





20901
ACATGGGTCA CAATCCTCTG TCCTAACTGA CTCAGAAAAA ACCAAGGCCA





20951
CAGCTCCAAT GGATACCACC TCCACCATGG GGCATACAAC TGTTTCCACA





21001
TCAATGTCTG TTTCCTCTGA GACTACAAAA ATTAAGAGAG AGTCAACATA





21051
TTCCTTGACT CCTGGACTGA GAGAGACCAG CATTTCCCAA AATGCCAGCT





21101
TTTCCACTGA CACAAGTATT GTTCTTTCAG AAGTCCCCAC TGGTACTACT





21151
GCTGAGGTCT CCAGGACAGA AGTCACCTCC TCTGGTAGAA CATCCATCCC





21201
TGGCCCTTCT CAGTCCACAG TTTTGCCAGA AATATCCACA AGAACAATGA





21251
CAAGGCTCTT TGCCTCGCCC ACCATGACAG AATCAGCAGA AATGACCATC





21301
CCCACTCAAA CAGGTCCTTC TGGGTCTACC TCACAGGATA CCCTTACCTT





21351
GGACACATCC ACCACAAAGT CCCAGGCAAA GACTCATTCA ACTTTGACTC





21401
AGAGATTTCC ACACTCAGAG ATGACCACTC TCATGAGCAG AGGTCCTGGA





21451
GATATGTCAT GGCAAAGCTC TCCCTCTCTG GAAAATCCCA GCTCTCTCCC





21501
TTCCCTGCTG TCTTTACCTG CCACAACCTC ACCTCCTCCC ATTTCCTCCA





21551
CATTACCAGT GACTATCTCC TCCTCTCCTC TTCCTGTGAC TTCACTTCTC





21601
ACCTCTAGCC CGGTAACGAC CACAGACATG TTACACACAA GCCCAGAACT





21651
TGTAACCAGT TCACCTCCAA AGCTGAGCCA CACTTCAGAT GAGAGACTGA





21701
CCACTGGCAA GGACACCACA AATACAGAAG CTGTGCATCC TTCCACAAAC





21751
ACAGCAGCGT CCAATGTGGA GATTCCCAGC TTTGGACATG AATCCCCTTC





21801
CTCTGCCTTA GCTGACTCAG AGACATCCAA AGCCACATCA CCAATGTTTA





21851
TTACCTCCAC CCAGGAGGAT ACAACTGTTG CCATATCAAC CCCTCACTTC





21901
TTGGAGACTA GCAGAATTCA GAAAGAGTCA ATTTCCTCCC TGAGCCCTAA





21951
ATTGAGGGAG ACAGGCAGTT CTGTGGAGAC AAGCTCAGCC ATAGAGACAA





22001
GTGCTGTCCT TTCTGAAGTG TCCATTGGTG CTACTACTGA GATCTCCAGG





22051
ACAGAAGTCA CCTCCTCTAG CAGAACATCC ATCTCTGGTT CTGCTGAGTC





22101
CACAATGTTG CCAGAAATAT CCACCACAAG AAAAATCATT AAGTTCCCTA





22151
CTTCCCCCAT CCTGGCAGAA TCATCAGAAA TGACCATCAA GACCCAAACA





22201
AGTCCTCCTG GGTCTACATC AGAGAGTACC TTTACATTAG ACACATCAAC





22251
CACTCCCTCC TTGGTAATAA CCCATTCGAC TATGACTCAG AGATTGCCAC





22301
ACTCAGAGAT AACCACTCTT GTGAGTAGAG GTGCTGGGGA TGTGCCACGG





22351
CCCAGCTCTC TCCCTGTGGA AGAAACAAGC CCTCCATCTT CCCAGCTGTC





22401
TTTATCTGCC ATGATCTCAC CTTCTCCTGT TTCTTCCACA TTACCAGCAA





22451
GTAGCCACTC CTCTTCTGCT TCTGTGACTT CACCTCTCAC ACCAGGCCAA





22501
GTGAAGACTA CTGAGGTGTT GGACGCAAGT GCAGAACCTG AAACCAGTTC





22551
ACCTCCAAGT TTGAGCAGCA CCTCAGTTGA AATACTGGCC ACCTCTGAAG





22601
TCACCACAGA TACGGAGAAA ATTCATCCTT TCCCAAACAC GGCAGTAACC





22651
AAAGTTGGAA CTTCCAGTTC TGGACATGAA TCCCCTTCCT CTGTCCTACC





22701
TGACTCAGAG ACAACCAAAG CCACATCGGC AATGGGTACC ATCTCCATTA





22751
TGGGGGATAC AAGTGTTTCT ACATTAACTC CTGCCTTATC TAACACTAGG





22801
AAAATTCAGT CAGAGCCAGC TTCCTCACTG ACCACCAGAT TGAGGGAGAC





22851
CAGCACCTCT GAAGAGACCA GCTTAGCCAC AGAAGCAAAC ACTGTTCTTT





22901
CTAAAGTGTC CACTGGTGCT ACTACTGAGG TCTCCAGGAC AGAAGCCATC





22951
TCCTTTAGCA GAACATCCAT GTCAGGCCCT GAGCAGTCCA CAATGTCACA





23001
AGACATCTCC ATAGGAACCA TCCCCAGGAT TTCTGCCTCC TCTGTCCTGA





23051
CAGAATCTGC AAAAATGACC ATCACAACCC AAACAGGTCC TTCGGAGTCT





23101
ACACTAGAAA GTACCCTTAA TTTGAACACA GCAACCACAC CCTCTTGGGT





23151
GGAAACCCAC TCTATAGTAA TTCAGGGATT TCCACACCCA GAGATGACCA





23201
CTTCCATGGG CAGAGGTCCT GGAGGTGTGT CATGGCCTAG CCCTCCCTTT





23251
GTGAAAGAAA CCAGCCCTCC ATCCTCCCCG CTGTCTTTAC CTGCCGTGAC





23301
CTCACCTCAT CCTGTTTCCA CCACATTCCT AGCACATATC CCCCCCTCTC





23351
CCCTTCCTGT GACTTCACTT CTCACCTCTG GCCCGGCGAC AACCACAGAT





23401
ATCTTGGGTA CAAGCACAGA ACCTGGAACC AGTTCATCTT CAAGTTTGAG





23451
CACCACCTCC CATGAGAGAC TGACCACTTA CAAAGACACT GCACATACAG





23501
AAGCCGTGCA TCCTTCCACA AACACAGGAG GGACCAATGT GGCAACCACC





23551
AGCTCTGGAT ATAAATCACA GTCCTCTGTC CTAGCTGACT CATCTCCAAT





23601
GTGTACCACC TCCACCATGG GGGATACAAG TGTTCTCACA TCAACTCCTG





23651
CCTTCCTTGA GACTAGGAGG ATTCAGACAG AGCTAGCTTC CTCCCTGACC





23701
CCTGGATTGA GGGAGTCCAG TGGCTCTGAA GGGACCAGCT CAGGCACCAA





23751
GATGAGCACT GTCCTCTCTA AAGTGCCCAC TGGTGCTACT ACTGAGATCT





23801
CCAAGGAAGA CGTCACCTCC ATCCCAGGTC CCGCTCAATC CACAATATCA





23851
CCAGACATCT CCACAAGAAC CGTCAGCTGG TTCTCTACAT CCCCTGTCAT





23901
GACAGAATCA GCAGAAATAA CCATGAACAC CCATACAAGT CCTTTAGGGG





23951
CCACAACACA AGGCACCAGT ACTTTGGCCA CGTCAAGCAC AACCTCTTTG





24001
ACAATGACAC ACTCAACTAT ATCTCAAGGA TTTTCACACT CACAGATGAG





24051
CACTCTTATG AGGAGGGGTC CTGAGGATGT ATCATGGATG AGCCCTCCCC





24101
TTCTGGAAAA AACTAGACCT TCCTTTTCTC TGATGTCTTC ACCAGCCACA





24151
ACTTCACCTT CTCCTGTTTC CTCCACATTA CCAGAGAGCA TCTCTTCCTC





24201
TCCTCTTCCT GTGACTTCAC TCCTCACGTC TGGCTTGGCA AAAACTACAG





24251
ATATGTTGCA CAAAAGCTCA GAACCTGTAA CCAACTCACC TGCAAATTTG





24301
AGCAGCACCT CAGTTGAAAT ACTGGCCACC TCTGAAGTCA CCACAGATAC





24351
AGAGAAAACT CATCCTTCTT CAAACAGAAC AGTGACCGAT GTGGGGACCT





24401
CCAGTTCTGG ACATGAATCC ACTTCCTTTG TCCTAGCTGA CTCACAGACA





24451
TCCAAAGTCA CATCTCCAAT GGTTATTACC TCCACCATGG AGGATACGAG





24501
TGTCTCCACA TCAACTCCTG GCTTTTTTGA GACTAGCAGA ATTCAGACAG





24551
AACCAACATC CTCCCTGACC CTTGGACTGA GAAAGACCAG CAGCTCTGAG





24601
GGGACCAGCT TAGCCACAGA GATGAGCACT GTCCTTTCTG GAGTGCCCAC





24651
TGGTGCCACT GCTGAAGTCT CCAGGACAGA AGTCACCTCC TCTAGCAGAA





24701
CATCCATCTC AGGCTTTGCT CAGCTCACAG TGTCACCAGA GACTTCCACA





24751
GAAACCATCA CCAGACTCCC TACCTCCAGC ATAATGACAG AATCAGCAGA





24801
AATGATGATC AAGACACAAA CAGATCCTCC TGGGTCTACA CCAGAGAGTA





24851
CTCATACTGT GGACATATCA ACAACACCCA ACTGGGTAGA AACCCACTCG





24901
ACTGTGACTC AGAGATTTTC ACACTCAGAG ATGACCACTC TTGTGAGCAG





24951
AAGCCCTGGT GATATGTTAT GGCCTAGTCA ATCCTCTGTG GAAGAAACCA





25001
GCTCTGCCTC TTCCCTGCTG TCTCTGCCTG CCACGACCTC ACCTTCTCCT





25051
GTTTCCTCTA CATTAGTAGA GGATTTCCCT TCCGCTTCTC TTCCTGTGAC





25101
TTCTCTTCTC ACCCCTGGCC TGGTGATAAC CACAGACAGG ATGGGCATAA





25151
GCAGAGAACC TGGAACCAGT TCCACTTCAA ATTTGAGCAG CACCTCCCAT





25201
GAGAGACTGA CCACTTTGGA AGACACTGTA GATACAGAAG ACATGCAGCC





25251
TTCCACACAC ACAGCAGTGA CCAACGTGAG GACCTCCATT TCTGGACATG





25301
AATCACAATC TTCTGTCCTA TCTGACTCAG AGACACCCAA AGCCACATCT





25351
CCAATGGGTA CCACCTACAC CATGGGGGAA ACGAGTGTTT CCATATCCAC





25401
TTCTGACTTC TTTGAGACCA GCAGAATTCA GATAGAACCA ACATCCTCCC





25451
TGACTTCTGG ATTGAGGGAG ACCAGCAGCT CTGAGAGGAT CAGCTCAGCC





25501
ACAGAGGGAA GCACTGTCCT TTCTGAAGTG CCCAGTGGTG CTACCACTGA





25551
GGTCTCCAGG ACAGAAGTGA TATCCTCTAG GGGAACATCC ATGTCAGGGC





25601
CTGATCAGTT CACCATATCA CCAGACATCT CTACTGAAGC GATCACCAGG





25651
CTTTCTACTT CCCCCATTAT GACAGAATCA GCAGAAAGTG CCATCACTAT





25701
TGAGACAGGT TCTCCTGGGG CTACATCAGA GGGTACCCTC ACCTTGGACA





25751
CCTCAACAAC AACCTTTTGG TCAGGGACCC ACTCAACTGC ATCTCCAGGA





25801
TTTTCACACT CAGAGATGAC CACTCTTATG AGTAGAACTC CTGGAGATGT





25851
GCCATGGCCG AGCCTTCCCT CTGTGGAAGA AGCCAGCTCT GTCTCTTCCT





25901
CACTGTCTTC ACCTGCCATG ACCTCAACTT CTTTTTTCTC CGCATTACCA





25951
GAGAGCATCT CCTCCTCTCC TCATCCTGTG ACTGCACTTC TCACCCTTGG





26001
CCCAGTGAAG ACCACAGACA TGTTGCGCAC AAGCTCAGAA CCTGAAACCA





26051
GTTCACCTCC AAATTTGAGC AGCACCTCAG CTGAAATATT AGCCACGTCT





26101
GAAGTCACCA AAGATAGAGA GAAAATTCAT CCCTCCTCAA ACACACCTGT





26151
AGTCAATGTA GGGACTGTGA TTTATAAACA TCTATCCCCT TCCTCTGTTT





26201
TGGCTGACTT AGTGACAACA AAACCCACAT CTCCAATGGC TACCACCTCC





26251
ACTCTGGGGA ATACAAGTGT TTCCACATCA ACTCCTGCCT TCCCAGAAAC





26301
TATGATGACA CAGCCAACTT CCTCCCTGAC TTCTGGATTA AGGGAGATCA





26351
GTACCTCTCA AGAGACCAGC TCAGCAACAG AGAGAAGTGC TTCTCTTTCT





26401
GGAATGCCCA CTGGTGCTAC TACTAAGGTC TCCAGAACAG AAGCCCTCTC





26451
CTTAGGCAGA ACATCCACCC CAGGTCCTGC TCAATCCACA ATATCACCAG





26501
AAATCTCCAC GGAAACCATC ACTAGAATTT CTACTCCCCT CACCACGACA





26551
GGATCAGCAG AAATGACCAT CACCCCCAAA ACAGGTCATT CTGGGGCATC





26601
CTCACAAGGT ACCTTTACCT TGGACACATC AAGCAGAGCC TCCTGGCCAG





26651
GAACTCACTC AGCTGCAACT CACAGATCTC CACACTCAGG GATGACCACT





26701
CCTATGAGCA GAGGTCCTGA GGATGTGTCA TGGCCAAGCC GCCCATCAGT





26751
GGAAAAAACT AGCCCTCCAT CTTCCCTGGT GTCTTTATCT GCAGTAACCT





26801
CACCTTCGCC ACTTTATTCC ACACCATCTG AGAGTAGCCA CTCATCTCCT





26851
CTCCGGGTGA CTTCTCTTTT CACCCCTGTC ATGATGAAGA CCACAGACAT





26901
GTTGGACACA AGCTTGGAAC CTGTGACCAC TTCACCTCCC AGTATGAATA





26951
TCACCTCAGA TGAGAGTCTG GCCACTTCTA AAGCCACCAT GGAGACAGAG





27001
GCAATTCAGC TTTCAGAAAA CACAGCTGTG ACTCAGATGG GCACCATCAG





27051
CGCTAGACAA GAATTCTATT CCTCTTATCC AGGCCTCCCA GAGCCATCCA





27101
AAGTGACATC TCCAGTGGTC ACCTCTTCCA CCATAAAAGA CATTGTTTCT





27151
ACAACCATAC CTGCTTCCTC TGAGATAACA AGAATTGAGA TGGAGTCAAC





27201
ATCCACCCTG ACCCCCACAC CAAGGGAGAC CAGCACCTCC CAGGAGATCC





27251
ACTCAGCCAC AAAGCCAAGC ACTGTTCCTT ACAAGGCACT CACTAGTGCC





27301
ACGATTGAGG ACTCCATGAC ACAAGTCATG TCCTCTAGCA GAGGACCTAG





27351
CCCTGATCAG TCCACAATGT CACAAGACAT ATCCAGTGAA GTGATCACCA





27401
GGCTCTCTAC CTCCCCCATC AAGGCAGAAT CTACAGAAAT GACCATTACC





27451
ACCCAAACAG GTTCTCCTGG GGCTACATCA AGGGGTACCC TTACCTTGGA





27501
CACTTCAACA ACTTTTATGT CAGGGACCCA CTCAACTGCA TCTCAAGGAT





27551
TTTCACACTC ACAGATGACC GCTCTTATGA GTAGAACTCC TGGAGATGTG





27601
CCATGGCTAA GCCATCCCTC TGTGGAAGAA GCCAGCTCTG CCTCTTTCTC





27651
ACTGTCTTCA CCTGTCATGA CCTCATCTTC TCCCGTTTCT TCCACATTAC





27701
CAGACAGCAT CCACTCTTCT TCGCTTCCTG TGACATCACT TCTCACCTCA





27751
GGGCTGGTGA AGACCACAGA GCTGTTGGGC ACAAGCTCAG AACCTGAAAC





27801
CAGTTCACCC CCAAATTTGA GCAGCACCTC AGCTGAAATA CTGGCCACCA





27851
CTGAAGTCAC TACAGATACA GAGAAACTGG AGATGACCAA TGTGGTAACC





27901
TCAGGTTATA CACATGAATC TCCTTCCTCT GTCCTAGCTG ACTCAGTGAC





27951
AACAAAGGCC ACATCTTCAA TGGGTATCAC CTACCCCACA GGAGATACAA





28001
ATGTTCTCAC ATCAACCCCT GCCTTCTCTG ACACCAGTAG GATTCAAACA





28051
AAGTCAAAGC TCTCACTGAC TCCTGGGTTG ATGGAGACCA GCATCTCTGA





28101
AGAGACCAGC TCTGCCACAG AAAAAAGCAC TGTCCTTTCT AGTGTGCCCA





28151
CTGGTGCTAC TACTGAGGTC TCCAGGACAG AAGCCATCTC TTCTAGCAGA





28201
ACATCCATCC CAGGCCCTGC TCAATCCACA ATGTCATCAG ACACCTCCAT





28251
GGAAACCATC ACTAGAATTT CTACCCCCCT CACAAGGAAA GAATCAACAG





28301
ACATGGCCAT CACCCCCAAA ACAGGTCCTT CTGGGGCTAC CTCGCAGGGT





28351
ACCTTTACCT TGGACTCATC AAGCACAGCC TCCTGGCCAG GAACTCACTC





28401
AGCTACAACT CAGAGATTTC CACAGTCAGT GGTGACAACT CCTATGAGCA





28451
GAGGTCCTGA GGATGTGTCA TGGCCAAGCC CGCTGTCTGT GGAAAAAAAC





28501
AGCCCTCCAT CTTCCCTGGT ATCTTCATCT TCAGTAACCT CACCTTCGCC





28551
ACTTTATTCC ACACCATCTG GGAGTAGCCA CTCCTCTCCT GTCCCTGTCA





28601
CTTCTCTTTT CACCTCTATC ATGATGAAGG CCACAGACAT GTTGGATGCA





28651
AGTTTGGAAC CTGAGACCAC TTCAGCTCCC AATATGAATA TCACCTCAGA





28701
TGAGAGTCTG GCCACTTCTA AAGCCACCAC GGAGACAGAG GCAATTCACG





28751
TTTTTGAAAA TACAGCAGCG TCCCATGTGG AAACCACCAG TGCTACAGAG





28801
GAACTCTATT CCTCTTCCCC AGGCTTCTCA GAGCCAACAA AAGTGATATC





28851
TCCAGTGGTC ACCTCTTCCT CTATAAGAGA CAACATGGTT TCCACAACAA





28901
TGCCTGGCTC CTCTGGCATT ACAAGGATTG AGATAGAGTC AATGTCATCT





28951
CTGACCCCTG GACTGAGGGA GACCAGAACC TCCCAGGACA TCACCTCATC





29001
CACAGAGACA AGCACTGTCC TTTACAAGAT GTCCTCTGGT GCCACTCCTG





29051
AGGTCTCCAG GACAGAAGTT ATGCCCTCTA GCAGAACATC CATTCCTGGC





29101
CCTGCTCAGT CCACAATGTC ACTAGACATC TCCGATGAAG TTGTCACCAG





29151
GCTGTCTACC TCTCCCATCA TGACAGAATC TGCAGAAATA ACCATCACCA





29201
CCCAAACAGG TTATTCTCTG GCTACATCCC AGGTTACCCT TCCCTTGGGC





29251
ACCTCAATGA CCTTTTTGTC AGGGACCCAC TCAACTATGT CTCAAGGACT





29301
TTCACACTCA GAGATGACCA ATCTTATGAG CAGGGGTCCT GAAAGTCTGT





29351
CATGGACGAG CCCTCGCTTT GTGGAAACAA CTAGATCTTC CTCTTCTCTG





29401
ACATCATTAC CTCTCACGAC CTCACTTTCT CCTGTGTCCT CCACATTACT





29451
AGACAGTAGC CCCTCCTCTC CTCTTCCTGT GACTTCACTT ATCCTCCCAG





29501
GCCTGGTGAA GACTACAGAA GTGTTGGATA CAAGCTCAGA GCCTAAAACC





29551
AGTTCATCTC CAAATTTGAG CAGCACCTCA GTTGAAATAC CGGCCACCTC





29601
TGAAATCATG ACAGATACAG AGAAAATTCA TCCTTCCTCA AACACAGCGG





29651
TGGCCAAAGT GAGGACCTCC AGTTCTGTTC ATGAATCTCA TTCCTCTGTC





29701
CTAGCTGACT CAGAAACAAC CATAACCATA CCTTCAATGG GTATCACCTC





29751
CGCTGTGGAC GATACCACTG TTTTCACATC AAATCCTGCC TTCTCTGAGA





29801
CTAGGAGGAT TCCGACAGAG CCAACATTCT CATTGACTCC TGGATTCAGG





29851
GAGACTAGCA CCTCTGAAGA GACCACCTCA ATCACAGAAA CAAGTGCAGT





29901
CCTTTATGGA GTGCCCACTA GTGCTACTAC TGAAGTCTCC ATGACAGAAA





29951
TCATGTCCTC TAATAGAACA CACATCCCTG ACTCTGATCA GTCCACGATG





30001
TCTCCAGACA TCATCACTGA AGTGATCACC AGGCTCTCTT CCTCATCCAT





30051
GATGTCAGAA TCAACACAAA TGACCATCAC CACCCAAAAA AGTTCTCCTG





30101
GGGCTACAGC ACAGAGTACT CTTACCTTGG CCACAACAAC AGCCCCCTTG





30151
GCAAGGACCC ACTCAACTGT TCCTCCTAGA TTTTTACACT CAGAGATGAC





30201
AACTCTTATG AGTAGGAGTC CTGAAAATCC ATCATGGAAG AGCTCTCCCT





30251
TTGTGGAAAA AACTAGCTCT TCATCTTCTC TGTTGTCCTT ACCTGTCACG





30301
ACCTCACCTT CTGTTTCTTC CACATTACCG CAGAGTATCC CTTCCTCCTC





30351
TTTTTCTGTG ACTTCACTCC TCACCCCAGG CATGGTGAAG ACTACAGACA





30401
CAAGCACAGA ACCTGGAACC AGTTTATCTC CAAATCTGAG TGGCACCTCA





30451
GTTGAAATAC TGGCTGCCTC TGAAGTCACC ACAGATACAG AGAAAATTCA





30501
TCCTTCTTCA AGCATGGCAG TGACCAATGT GGGAACCACC AGTTCTGGAC





30551
ATGAACTATA TTCCTCTGTT TCAATCCACT CGGAGCCATC CAAGGCTACA





30601
TACCCAGTGG GTACTCCCTC TTCCATGGCT GAAACCTCTA TTTCCACATC





30651
AATGCCTGCT AATTTTGAGA CCACAGGATT TGAGGCTGAG CCATTTTCTC





30701
ATTTGACTTC TGGATTTAGG AAGACAAACA TGTCCCTGGA CACCAGCTCA





30751
GTCACACCAA CAAATACACC TTCTTCTCCT GGGTCCACTC ACCTTTTACA





30801
GAGTTCCAAG ACTGATTTCA CCTCTTCTGC AAAAACATCA TCCCCAGACT





30851
GGCCTCCAGC CTCACAGTAT ACTGAAATTC CAGTGGACAT AATCACCCCC





30901
TTTAATGCTT CTCCATCTAT TACGGAGTCC ACTGGGATAA CCTCCTTCCC





30951
AGAATCCAGG TTTACTATGT CTGTAACAGA AAGTACTCAT CATCTGAGTA





31001
CAGATTTGCT GCCTTCAGCT GAGACTATTT CCACTGGCAC AGTGATGCCT





31051
TCTCTATCAG AGGCCATGAC TTCATTTGCC ACCACTGGAG TTCCACGAGC





31101
CATCTCAGGT TCAGGTAGTC CATTCTCTAG GACAGAGTCA GGCCCTGGGG





31151
ATGCTACTCT GTCCACCATT GCAGAGAGCC TGCCTTCATC CACTCCTGTG





31201
CCATTCTCCT CTTCAACCTT CACTACCACT GATTCTTCAA CCATCCCAGC





31251
CCTCCATGAG ATAACTTCCT CTTCAGCTAC CCCATATAGA GTGGACACCA





31301
GTCTTGGGAC AGAGAGCAGC ACTACTGAAG GACGCTTGGT TATGGTCAGT





31351
ACTTTGGACA CTTCAAGCCA ACCAGGCAGG ACATCTTCAA CACCCATTTT





31401
GGATACCAGA ATGACAGAGA GCGTTGAGCT GGGAACAGTG ACAAGTGCTT





31451
ATCAAGTTCC TTCACTCTCA ACACGGTTGA CAAGAACTGA TGGCATTATG





31501
GAACACATCA CAAAAATACC CAATGAAGCA GCACACAGAG GTACCATAAG





31551
ACCAGTCAAA GGCCCTCAGA CATCCACTTC GCCTGCCAGT CCTAAAGGAC





31601
TACACACAGG AGGGACAAAA AGAATGGAGA CCACCACCAC AGCTTTGAAG





31651
ACCACCACCA CAGCTTTGAA GACCACTTCC AGAGCCACCT TGACCACCAG





31701
TGTCTATACT CCCACTTTGG GAACACTGAC TCCCCTCAAT GCATCAAGGC





31751
AAATGGCCAG CACAATCCTC ACAGAAATGA TGATCACAAC CCCATATGTT





31801
TTCCCTGATG TTCCAGAAAC GACATCCTCA TTGGCTACCA GCCTGGGAGC





31851
AGAAACCAGC ACAGCTCTTC CCAGGACAAC CCCATCTGTT CTCAATAGAG





31901
AATCAGAGAC CACAGCCTCA CTGGTCTCTC GTTCTGGGGC AGAGAGAAGT





31951
CCGGTTATTC AAACTCTAGA TGTTTCTTCT AGTGAGCCAG ATACAACAGC





32001
TTCATGGGTT ATCCATCCTG CAGAGACCAT CCCAACTGTT TCCAAGACAA





32051
CCCCCAATTT TTTCCACAGT GAATTAGACA CTGTATCTTC CACAGCCACC





32101
AGTCATGGGG CAGACGTCAG CTCAGCCATT CCAACAAATA TCTCACCTAG





32151
TGAACTAGAT GCACTGACCC CACTGGTCAC TATTTCGGGG ACAGATACTA





32201
GTACAACATT CCCAACACTG ACTAAGTCCC CACATGAAAC AGAGACAAGA





32251
ACCACATGGC TCACTCATCC TGCAGAGACC AGCTCAACTA TTCCCAGAAC





32301
AATCCCCAAT TTTTCTCATC ATGAATCAGA TGCCACACCT TCAATAGCCA





32351
CCAGTCCTGG GGCAGAAACC AGTTCAGCTA TTCCAATTAT GACTGTCTCA





32401
CCTGGTGCAG AAGATCTGGT GACCTCACAG GTCACTAGTT CTGGGACAGA





32451
CAGAAATATG ACTATTCCAA CTTTGACTCT TTCTCCTGGT GAACCAAAGA





32501
CGATAGCCTC ATTAGTCACC CATCCTGAAG CACAGACAAG TTCGGCCATT





32551
CCAACTTCAA CTATCTCGCC TGCTGTATCA CGGTTGGTGA CCTCAATGGT





32601
CACCAGTTTG GCGGCAAAGA CAAGTACAAC TAATCGAGCT CTGACAAACT





32651
CCCCTGGTGA ACCAGCTACA ACAGTTTCAT TGGTCACGCA TCCTGCACAG





32701
ACCAGCCCAA CAGTTCCCTG GACAACTTCC ATTTTTTTCC ATAGTAAATC





32751
AGACACCACA CCTTCAATGA CCACCAGTCA TGGGGCAGAA TCCAGTTCAG





32801
CTGTTCCAAC TCCAACTGTT TCAACTGAGG TACCAGGAGT AGTGACCCCT





32851
TTGGTCACCA GTTCTAGGGC AGTGATCAGT ACAACTATTC CAATTCTGAC





32901
TCTTTCTCCT GGTGAACCAG AGACCACACC TTCAATGGCC ACCAGTCATG





32951
GGGAAGAAGC CAGTTCTGCT ATTCCAACTC CAACTGTTTC ACCTGGGGTA





33001
CCAGGAGTGG TGACCTCTCT GGTCACTAGT TCTAGGGCAG TGACTAGTAC





33051
AACTATTCCA ATTCTGACTT TTTCTCTTGG TGAACCAGAG ACCACACCTT





33101
CAATGGCCAC CAGTCATGGG ACAGAAGCTG GCTCAGCTGT TCCAACTGTT





33151
TTACCTGAGG TACCAGGAAT GGTGACCTCT CTGGTTGCTA GTTCTAGGGC





33201
AGTAACCAGT ACAACTCTTC CAACTCTGAC TCTTTCTCCT GGTGAACCAG





33251
AGACCACACC TTCAATGGCC ACCAGTCATG GGGCAGAAGC CAGCTCAACT





33301
GTTCCAACTG TTTCACCTGA GGTACCAGGA GTGGTGACCT CTCTGGTCAC





33351
TAGTTCTAGT GGAGTAAACA GTACAAGTAT TCCAACTCTG ATTCTTTCTC





33401
CTGGTGAACT AGAAACCACA CCTTCAATGG CCACCAGTCA TGGGGCAGAA





33451
GCCAGCTCAG CTGTTCCAAC TCCAACTGTT TCACCTGGGG TATCAGGAGT





33501
GGTGACCCCT CTGGTCACTA GTTCCAGGGC AGTGACCAGT ACAACTATTC





33551
CAATTCTAAC TCTTTCTTCT AGTGAGCCAG AGACCACACC TTCAATGGCC





33601
ACCAGTCATG GGGTAGAAGC CAGCTCAGCT GTTCTAACTG TTTCACCTGA





33651
GGTACCAGGA ATGGTGACCT CTCTGGTCAC TAGTTCTAGA GCAGTAACCA





33701
GTACAACTAT TCCAACTCTG ACTATTTCTT CTGATGAACC AGAGACCACA





33751
ACTTCATTGG TCACCCATTC TGAGGCAAAG ATGATTTCAG CCATTCCAAC





33801
TTTAGCTGTC TCCCCTACTG TACAAGGGCT GGTGACTTCA CTGGTCACTA





33851
GTTCTGGGTC AGAGACCAGT GCGTTTTCAA ATCTAACTGT TGCCTCAAGT





33901
CAACCAGAGA CCATAGACTC ATGGGTCGCT CATCCTGGGA CAGAAGCAAG





33951
TTCTGTTGTT CCAACTTTGA CTGTCTCCAC TGGTGAGCCG TTTACAAATA





34001
TCTCATTGGT CACCCATCCT GCAGAGAGTA GCTCAACTCT TCCCAGGACA





34051
ACCTCAAGGT TTTCCCACAG TGAATTAGAC ACTATGCCTT CTACAGTCAC





34101
CAGTCCTGAG GCAGAATCCA GCTCAGCCAT TTCAACTACT ATTTCACCTG





34151
GTATACCAGG TGTGCTGACA TCACTGGTCA CTAGCTCTGG GAGAGACATC





34201
AGTGCAACTT TTCCAACAGT GCCTGAGTCC CCACATGAAT CAGAGGCAAC





34251
AGCCTCATGG GTTACTCATC CTGCAGTCAC CAGCACAACA GTTCCCAGGA





34301
CAACCCCTAA TTATTCTCAT AGTGAACCAG ACACCACACC ATCAATAGCC





34351
ACCAGTCCTG GGGCAGAAGC CACTTCAGAT TTTCCAACAA TAACTGTCTC





34401
ACCTGATGTA CCAGATATGG TAACCTCACA GGTCACTAGT TCTGGGACAG





34451
ACACCAGTAT AACTATTCCA ACTCTGACTC TTTCTTCTGG TGAGCCAGAG





34501
ACCACAACCT CATTTATCAC CTATTCTGAG ACACACACAA GTTCAGCCAT





34551
TCCAACTCTC CCTGTCTCCC CTGGTGCATC AAAGATGCTG ACCTCACTGG





34601
TCATCAGTTC TGGGACAGAC AGCACTACAA CTTTCCCAAC ACTGACGGAG





34651
ACCCCATATG AACCAGAGAC AACAGCCATA CAGCTCATTC ATCCTGCAGA





34701
GACCAACACA ATGGTTCCCA AGACAACTCC CAAGTTTTCC CATAGTAAGT





34751
CAGACACCAC ACTCCCAGTA GCCATCACCA GTCCTGGGCC AGAAGCCAGT





34801
TCAGCTGTTT CAACGACAAC TATCTCACCT GATATGTCAG ATCTGGTGAC





34851
CTCACTGGTC CCTAGTTCTG GGACAGACAC CAGTACAACC TTCCCAACAT





34901
TGAGTGAGAC CCCATATGAA CCAGAGACTA CAGTCACGTG GCTCACTCAT





34951
CCTGCAGAAA CCAGCACAAC GGTTTCTGGG ACAATTCCCA ACTTTTCCCA





35001
TAGGGGATCA GACACTGCAC CCTCAATGGT CACCAGTCCT GGAGTAGACA





35051
CGAGGTCAGG TGTTCCAACT ACAACCATCC CACCCAGTAT ACCAGGGGTA





35101
GTGACCTCAC AGGTCACTAG TTCTGCAACA GACACTAGTA CAGCTATTCC





35151
AACTTTGACT CCTTCTCCTG GTGAACCAGA GACCACAGCC TCATCAGCTA





35201
CCCATCCTGG GACACAGACT GGCTTCACTG TTCCAATTCG GACTGTTCCC





35251
TCTAGTGAGC CAGATACAAT GGCTTCCTGG GTCACTCATC CTCCACAGAC





35301
CAGCACACCT GTTTCCAGAA CAACCTCCAG TTTTTCCCAT AGTAGTCCAG





35351
ATGCCACACC TGTAATGGCC ACCAGTCCTA GGACAGAAGC CAGTTCAGCT





35401
GTACTGACAA CAATCTCACC TGGTGCACCA GAGATGGTGA CTTCACAGAT





35451
CACTAGTTCT GGGGCAGCAA CCAGTACAAC TGTTCCAACT TTGACTCATT





35501
CTCCTGGTAT GCCAGAGACC ACAGCCTTAT TGAGCACCCA TCCCAGAACA





35551
GGGACAAGTA AAACATTTCC TGCTTCAACT GTGTTTCCTC AAGTATCAGA





35601
GACCACAGCC TCACTCACCA TTAGACCTGG TGCAGAGACT AGCACAGCTC





35651
TCCCAACTCA GACAACATCC TCTCTCTTCA CCCTACTTGT AACTGGAACC





35701
AGCAGAGTTG ATCTAAGTCC AACTGCTTCA CCTGGTGTTT CTGCAAAAAC





35751
AGCCCCACTT TCCACCCATC CAGGGACAGA GACCAGCACA ATGATTCCAA





35801
CTTCAACTCT TTCCCTTGGT TTACTAGAGA CTACAGGCTT ACTGGCCACC





35851
AGCTCTTCAG CAGAGACCAG CACGAGTACT CTAACTCTGA CTGTTTCCCC





35901
TGCTGTCTCT GGGCTTTCCA GTGCCTCTAT AACAACTGAT AAGCCCCAAA





35951
CTGTGACCTC CTGGAACACA GAAACCTCAC CATCTGTAAC TTCAGTTGGA





36001
CCCCCAGAAT TTTCCAGGAC TGTCACAGGC ACCACTATGA CCTTGATACC





36051
ATCAGAGATG CCAACACCAC CTAAAACCAG TCATGGAGAA GGAGTGAGTC





36101
CAACCACTAT CTTGAGAACT ACAATGGTTG AAGCCACTAA TTTAGCTACC





36151
ACAGGTTCCA GTCCCACTGT GGCCAAGACA ACAACCACCT TCAATACACT





36201
GGCTGGAAGC CTCTTTACTC CTCTGACCAC ACCTGGGATG TCCACCTTGG





36251
CCTCTGAGAG TGTGACCTCA AGAACAAGTT ATAACCATCG GTCCTGGATC





36301
TCCACCACCA GCAGTTATAA CCGTCGGTAC TGGACCCCTG CCACCAGCAC





36351
TCCAGTGACT TCTACATTCT CCCCAGGGAT TTCCACATCC TCCATCCCCA





36401
GCTCCACAGC AGCCACAGTC CCATTCATGG TGCCATTCAC CCTCAACTTC





36451
ACCATCACCA ACCTGCAGTA CGAGGAGGAC ATGCGGCACC CTGGTTCCAG





36501
GAAGTTCAAC GCCACAGAGA GAGAACTGCA GGGTCTGCTC AAACCCTTGT





36551
TCAGGAATAG CAGTCTGGAA TACCTCTATT CAGGCTGCAG ACTAGCCTCA





36601
CTCAGGCCAG AGAAGGATAG CTCAGCCATG GCAGTGGATG CCATCTGCAC





36651
ACATCGCCCT GACCCTGAAG ACCTCGGACT GGACAGAGAG CGACTGTACT





36701
GGGAGCTGAG CAATCTGACA AATGGCATCC AGGAGCTGGG CCCCTACACC





36751
CTGGACCGGA ACAGTCTCTA TGTCAATGGT TTCACCCATC GAAGCTCTAT





36801
GCCCACCACC AGCACTCCTG GGACCTCCAC AGTGGATGTG GGAACCTCAG





36851
GGACTCCATC CTCCAGCCCC AGCCCCACGG CTGCTGGCCC TCTCCTGATG





36901
CCGTTCACCC TCAACTTCAC CATCACCAAC CTGCAGTACG AGGAGGACAT





36951
GCGTCGCACT GGCTCCAGGA AGTTCAACAC CATGGAGAGT GTCCTGCAGG





37001
GTCTGCTCAA GCCCTTGTTC AAGAACACCA GTGTTGGCCC TCTGTACTCT





37051
GGCTGCAGAT TGACCTTGCT CAGGCCCGAG AAAGATGGGG CAGCCACTGG





37101
AGTGGATGCC ATCTGCACCC ACCGCCTTGA CCCCAAAAGC CCTGGACTCA





37151
ACAGGGAGCA GCTGTACTGG GAGCTAAGCA AACTGACCAA TGACATTGAA





37201
GAGCTGGGCC CCTACACCCT GGACAGGAAC AGTCTCTATG TCAATGGTTT





37251
CACCCATCAG AGCTCTGTGT CCACCACCAG CACTCCTGGG ACCTCCACAG





37301
TGGATCTCAG AACCTCAGGG ACTCCATCCT CCCTCTCCAG CCCCACAATT





37351
ATGGCTGCTG GCCCTCTCCT GGTACCATTC ACCCTCAACT TCACCATCAC





37401
CAACCTGCAG TATGGGGAGG ACATGGGTCA CCCTGGCTCC AGGAAGTTCA





37451
ACACCACAGA GAGGGTCCTG CAGGGTCTGC TTGGTCCCAT ATTCAAGAAC





37501
ACCAGTGTTG GCCCTCTGTA CTCTGGCTGC AGACTGACCT CTCTCAGGTC





37551
TGAGAAGGAT GGAGCAGCCA CTGGAGTGGA TGCCATCTGC ATCCATCATC





37601
TTGACCCCAA AAGCCCTGGA CTCAACAGAG AGCGGCTGTA CTGGGAGCTG





37651
AGCCAACTGA CCAATGGCAT CAAAGAGCTG GGCCCCTACA CCCTGGACAG





37701
GAACAGTCTC TATGTCAATG GTTTCACCCA TCGGACCTCT GTGCCCACCA





37751
CCAGCACTCC TGGGACCTCC ACAGTGGACC TTGGAACCTC AGGGACTCCA





37801
TTCTCCCTCC CAAGCCCCGC AACTGCTGGC CCTCTCCTGG TGCTGTTCAC





37851
CCTCAACTTC ACCATCACCA ACCTGAAGTA TGAGGAGGAC ATGCATCGCC





37901
CTGGCTCCAG GAAGTTCAAC ACCACTGAGA GGGTCCTGCA GACTCTGCTT





37951
GGTCCTATGT TCAAGAACAC CAGTGTTGGC CTTCTGTACT CTGGCTGCAG





38001
ACTGACCTTG CTCAGGTCCG AGAAGGATGG AGCAGCCACT GGAGTGGATG





38051
CCATCTGCAC CCACCGTCTT GACCCCAAAA GCCCTGGACT GGACAGAGAG





38101
CAGCTATACT GGGAGCTGAG CCAGCTGACC AATGGCATCA AAGAGCTGGG





38151
CCCCTACACC CTGGACAGGA ACAGTCTCTA TGTCAATGGT TTCACCCATT





38201
GGATCCCTGT GCCCACCAGC AGCACTCCTG GGACCTCCAC AGTGGACCTT





38251
GGGTCAGGGA CTCCATCCTC CCTCCCCAGC CCCACAGCTG CTGGCCCTCT





38301
CCTGGTGCCA TTCACCCTCA ACTTCACCAT CACCAACCTG CAGTACGAGG





38351
AGGACATGCA TCACCCAGGC TCCAGGAAGT TCAACACCAC GGAGCGGGTC





38401
CTGCAGGGTC TGCTTGGTCC CATGTTCAAG AACACCAGTG TCGGCCTTCT





38451
GTACTCTGGC TGCAGACTGA CCTTGCTCAG GTCCGAGAAG GATGGAGCAG





38501
CCACTGGAGT GGATGCCATC TGCACCCACC GTCTTGACCC CAAAAGCCCT





38551
GGAGTGGACA GGGAGCAGCT ATACTGGGAG CTGAGCCAGC TGACCAATGG





38601
CATCAAAGAG CTGGGTCCCT ACACCCTGGA CAGAAACAGT CTCTATGTCA





38651
ATGGTTTCAC CCATCAGACC TCTGCGCCCA ACACCAGCAC TCCTGGGACC





38701
TCCACAGTGG ACCTTGGGAC CTCAGGGACT CCATCCTCCC TCCCCAGCCC





38751
TACATCNGCT GGCCCTCTCC TGGTNCCNTT CACCCTCAAC TTCACCATCA





38801
CCAACCTGCA GTACGAGGAG GACATGCGGC ACCCNGGNTC CAGGAAGTTC





38851
AACACCACNG AGAGGGTNCT GCAGGGTCTG CTNAAGCCCC TNTTCAAGAG





38901
CACCAGTGTT GGCCCTCTGT ACTCTGGCTG CAGACTGACC TTGCTCAGGT





38951
CCGAGAAGGA TGGAGCAGCC ACTGGAGTGG ATGCCATCTG CACCCACCGT





39001
CTTGACCCCA AAAGCCCTGG AGTGGACAGG GAGCAGCTAT ACTGGGAGCT





39051
GAGCCAGCTG ACCAATGGCA TCAAAGAGCT GGGTCCCTAC ACCCTGGACA





39101
GAAACAGTCT CTATGTCAAT GGTTTCACCC ATCAGACCTC TGCGCCCAAC





39151
ACCAGCACTC CTGGGACCTC CACAGTGGAC CTTGGGACCT CAGGGACTCC





39201
ATCCTCCCTC CCCAGCCCTA CATCTGCTGG CCCTCTCCTG GTGCCATTCA





39251
CCCTCAACTT CACCATCACC AACCTGCAGT ACGAGGAGGA CATGCATCAC





39301
CCAGGCTCCA GGAAGTTCAA CACCACGGAG CGGGTCCTGC AGGGTCTGCT





39351
TGGTCCCATG TTCAAGAACA CCAGTGTCGG CCTTCTGTAC TCTGGCTGCA





39401
GACTGACCTT GCTCAGGCCT GAGAAGAATG GGGCAGCCAC TGGAATGGAT





39451
GCCATCTGCA GCCACCGTCT TGACCCCAAA AGCCCTGGAC TCAACAGAGA





39501
GCAGCTGTAC TGGGAGCTGA GCCAGCTGAC CCATGGCATC AAAGAGCTGG





39551
GCCCCTACAC CCTGGACAGG AACAGTCTCT ATGTCAATGG TTTCACCCAT





39601
CGGAGCTCTG TGGCCCCCAC CAGCACTCCT GGGACCTCCA CAGTGGACCT





39651
TGGGACCTCA GGGACTCCAT CCTCCCTCCC CAGCCCCACA ACAGCTGTTC





39701
CTCTCCTGGT GCCGTTCACC CTCAACTTTA CCATCACCAA TCTGCAGTAT





39751
GGGGAGGACA TGCGTCACCC TGGCTCCAGG AAGTTCAACA CCACAGAGAG





39801
GGTCCTGCAG GGTCTGCTTG GTCCCTTGTT CAAGAACTCC AGTGTCGGCC





39851
CTCTGTACTC TGGCTGCAGA CTGATCTCTC TCAGGTCTGA GAAGGATGGG





39901
GCAGCCACTG GAGTGGATGC CATCTGCACC CACCACCTTA ACCCTCAAAG





39951
CCCTGGACTG GACAGGGAGC AGCTGTACTG GCAGCTGAGC CAGATGACCA





40001
ATGGCATCAA AGAGCTGGGC CCCTACACCC TGGACCGGAA CAGTCTCTAC





40051
GTCAATGGTT TCACCCATCG GAGCTCTGGG CTCACCACCA GCACTCCTTG





40101
GACTTCCACA GTTGACCTTG GAACCTCAGG GACTCCATCC CCCGTCCCCA





40151
GCCCCACAAC TGCTGGCCCT CTCCTGGTGC CATTCACCCT CAACTTCACC





40201
ATCACCAACC TGCAGTATGA GGAGGACATG CATCGCCCTG GATCTAGGAA





40251
GTTCAACACC ACAGAGAGGG TCCTGCAGGG TCTGCTTAGT CCCATTTTCA





40301
AGAACTCCAG TGTTGGCCCT CTGTACTCTG GCTGCAGACT GACCTCTCTC





40351
AGGCCCGAGA AGGATGGGGC AGCAACTGGA ATGGATGCTG TCTGCCTCTA





40401
CCACCCTAAT CCCAAAAGAC CTGGACTGGA CAGAGAGCAG CTGTACTGGG





40451
AGCTAAGCCA GCTGACCCAC AACATCACTG AGCTGGGCCC CTACAGCCTG





40501
GACAGGGACA GTCTCTATGT CAATGGTTTC ACCCATCAGA ACTCTGTGCC





40551
CACCACCAGT ACTCCTGGGA CCTCCACAGT GTACTGGGCA ACCACTGGGA





40601
CTCCATCCTC CTTCCCCGGC CACACAGAGC CTGGCCCTCT CCTGATACCA





40651
TTCACTTTCA ACTTTACCAT CACCAACCTG CATTATGAGG AAAACATGCA





40701
ACACCCTGGT TCCAGGAAGT TCAACACCAC GGAGAGGGTT CTGCAGGGTC





40751
TGCTCAAGCC CTTGTTCAAG AACACCAGTG TTGGCCCTCT GTACTCTGGC





40801
TGCAGACTGA CCTCTCTCAG GCCCGAGAAG GATGGGGCAG CAACTGGAAT





40851
GGATGCTGTC TGCCTCTACC ACCCTAATCC CAAAAGACCT GGGCTGGACA





40901
GAGAGCAGCT GTACTGGGAG CTAAGCCAGC TGACCCACAA CATCACTGAG





40951
CTGGGCCCCT ACAGCCTGGA CAGGGACAGT CTCTATGTCA ATGGTTTCAC





41001
CCATCAGAAC TCTGTGCCCA CCACCAGTAC TCCTGGGACC TCCACAGTGT





41051
ACTGGGCAAC CACTGGGACT CCATCCTCCT TCCCCGGCCA CACAGAGCCT





41101
GGCCCTCTCC TGATACCATT CACTTTCAAC TTTACCATCA CCAACCTGCA





41151
TTATGAGGAA AACATGCAAC ACCCTGGTTC CAGGAAGTTC AACACCACGG





41201
AGAGGGTTCT GCAGGGTCTG CTCAAGCCCT TGTTCAAGAA CACCAGTGTT





41251
GGCCCTCTGT ACTCTGGCTG CAGACTGACC TTGCTCAGAC CTGAGAAGCA





41301
TGAGGCAGCC ACTGGAGTGG ACACCATCTG TACCCACCGC GTTGATCCCA





41351
TCGGACCTGG ACTGGACAGG GAGCGGCTAT ACTGGGAGCT GAGCCAGCTG





41401
ACCAACAGCA TTACCGAACT GGGACCCTAC ACCCTGGACA GGGACAGTCT





41451
CTATGTCAAT GGCTTCAACC CTCGGAGCTC TGTGCCAACC ACCAGCACTC





41501
CTGGGACCTC CACAGTGCAC CTGGCAACCT CTGGGACTCC ATCCTCCCTG





41551
CCTGGCCACA CAGCCCCTGT CCCTCTCTTG ATACCATTCA CCCTCAACTT





41601
TACCATCACC AACCTGCATT ATGAGGAAAA CATGCAACAC CCTGGTTCCA





41651
GGAAGTTCAA CACCACGGAG AGGGTTCTGC AGGGTCTGCT CAAGCCCTTG





41701
TTCAAGAACA CCAGTGTTGG CCCTCTGTAC TCTGGCTGCA GACTGACCTT





41751
GCTCAGACCT GAGAAGCATG AGGCAGCCAC TGGAGTGGAC ACCATCTGTA





41801
CCCACCGCGT TGATCCCATC GGACCTGGAC TGNACAGNGA GCNGCTNTAC





41851
TGGGAGCTNA GCCANCTGAC CAANNNCATC NNNGAGCTGG GNCCCTACAC





41901
CCTGGACAGG NACAGTCTCT ATGTCAATGG TTTCACCCAT CNGANCTCTG





41951
NGCCCACCAC CAGCACTCCT GGGACCTCCA CAGTGNACNT NGGNACCTCN





42001
GGGACTCCAT CCTCCNTCCC CNGCCNCACA TCTGCTGGCC CTCTCCTGGT





42051
GCCATTCACC CTCAACTTCA CCATCACCAA CCTGCAGTAC GAGGAGGACA





42101
TGCATCACCC AGGCTCCAGG AAGTTCAACA CCACGGAGCG GGTCCTGCAG





42151
GGTCTGCTTG GTCCCATGTT CAAGAACACC AGTGTCGGCC TTCTGTACTC





42201
TGGCTGCAGA CTGACCTTGC TCAGGCCTGA GAAGAATGGG GCAGCCACTG





42251
GAATGGATGC CATCTGCAGC CACCGTCTTG ACCCCAAAAG CCCTGGACTC





42301
GACAGAGAGC AGCTGTACTG GGAGCTGAGC CAGCTGACCC ATGGCATCAA





42351
AGAGCTGGGC CCCTACACCC TGGACAGGAA CAGTCTCTAT GTCAATGGTT





42401
TCACCCATCG GAGCTCTGTG GCCCCCACCA GCACTCCTGG GACCTCCACA





42451
GTGGACCTTG GGACCTCAGG GACTCCATCC TCCCTCCCCA GCCCCACAAC





42501
AGCTGTTCCT CTCCTGGTGC CGTTCACCCT CAACTTTACC ATCACCAATC





42551
TGCAGTATGG GGAGGACATG CGTCACCCTG GCTCCAGGAA GTTCAACACC





42601
ACAGAGAGGG TCCTGCAGGG TCTGCTTGGT CCCTTGTTCA AGAACTCCAG





42651
TGTCGGCCCT CTGTACTCTG GCTGCAGACT GATCTCTCTC AGGTCTGAGA





42701
AGGATGGGGC AGCCACTGGA GTGGATGCCA TCTGCACCCA CCACCTTAAC





42751
CCTCAAAGCC CTGGACTGGA CAGGGAGCAG CTGTACTGGC AGCTGAGCCA





42801
GATGACCAAT GGCATCAAAG AGCTGGGCCC CTACACCCTG GACCGGAACA





42851
GTCTCTACGT CAATGGTTTC ACCCATCGGA GCTCTGGGCT CACCACCAGC





42901
ACTCCTTGGA CTTCCACAGT TGACCTTGGA ACCTCAGGGA CTCCATCCCC





42951
CGTCCCCAGC CCCACAACTG CTGGCCCTCT CCTGGTGCCA TTCACCCTAA





43001
ACTTCACCAT CACCAACCTG CAGTATGAGG AGGACATGCA TCGCCCTGGA





43051
TCTAGGAAGT TCAACGCCAC AGAGAGGGTC CTGCAGGGTC TGCTTAGTCC





43101
CATATTCAAG AACTCCAGTG TTGGCCCTCT GTACTCTGGC TGCAGACTGA





43151
CCTCTCTCAG GCCCGAGAAG GATGGGGCAG CAACTGGAAT GGATGCTGTC





43201
TGCCTCTACC ACCCTAATCC CAAAAGACCT GGACTGGACA GAGAGCAGCT





43251
GTACTGGGAG CTAAGCCAGC TGACCCACAA CATCACTGAG CTGGGCCCCT





43301
ACAGCCTGGA CAGGGACAGT CTCTATGTCA ATGGTTTCAC CCATCAGAGC





43351
TCTATGACGA CCACCAGAAC TCCTGATACC TCCACAATGC ACCTGGCAAC





43401
CTCGAGAACT CCAGCCTCCC TGTCTGGACC TACGACCGCC AGCCCTCTCC





43451
TGGTGCTATT CACAATCAAC TGCACCATCA CCAACCTGCA GTACGAGGAG





43501
GACATGCGTC GCACTGGCTC CAGGAAGTTC AACACCATGG AGAGTGTCCT





43551
GCAGGGTCTG CTCAAGCCCT TGTTCAAGAA CACCAGTGTT GGCCCTCTGT





43601
ACTCTGGCTG CAGATTGACC TTGCTCAGGC CCAAGAAAGA TGGGGCAGCC





43651
ACTGGAGTGG ATGCCATCTG CACCCACCGC CTTGACCCCA AAAGCCCTGG





43701
ACTCAACAGG GAGCAGCTGT ACTGGGAGCT AAGCAAACTG ACCAATGACA





43751
TTGAAGAGCT GGGCCCCTAC ACCCTGGACA GGAACAGTCT CTATGTCAAT





43801
GGTTTCACCC ATCAGAGCTC TGTGTCCACC ACCAGCACTC CTGGGACCTC





43851
CACAGTGGAT CTCAGAACCT CAGGGACTCC ATCCTCCCTC TCCAGCCCCA





43901
CAATTATGNC NNCTGNCCCT CTCCTGNTNC CNTTCACCNT CAACTTNACC





43951
ATCACCAACC TGCANTANGN GGANNACATG CNNCNCCCNG GNTCCAGGAA





44001
GTTCAACACC ACNGAGAGGG TCCTACAGGG TCTGCTCAGG CCCTTGTTCA





44051
AGAACACCAG TGTCAGCTCT CTGTACTCTG GTTGCAGACT GACCTTGCTC





44101
AGGCCTGAGA AGGATGGGGC AGCCACCAGA GTGGATGCTG CCTGCACCTA





44151
CCGCCCTGAT CCCAAAAGCC CTGGACTGGA CAGAGAGCAA CTATACTGGG





44201
AGCTGAGCCA GCTAACCCAC AGCATCACTG AGCTGGGACC CTACACCCTG





44251
GACAGGGTCA GTCTCTATGT CAATGGCTTC AACCCTCGGA GCTCTGTGCC





44301
AACCACCAGC ACTCCTGGGA CCTCCACAGT GCACCTGGCA ACCTCTGGGA





44351
CTCCATCCTC CCTGCCTGGC CACACANCNN CTGNCCCTCT CCTGNTNCCN





44401
TTCACCNTCA ACTTNACCAT CACCAACCTG CANTANGNGG ANNACATGCN





44451
NCNCCCNGGN TCCAGGAAGT TCAACACCAC NGAGAGGGTT CTGCAGGGTC





44501
TGCTCAAACC CTTGTTCAGG AATAGCAGTC TGGAATACCT CTATTCAGGC





44551
TGCAGACTAG CCTCACTCAG GCCAGAGAAG GATAGCTCAG CCATGGCAGT





44601
GGATGCCATC TGCACACATC GCCCTGACCC TGAAGACCTC GGACTGGACA





44651
GAGAGCGACT GTACTGGGAG CTGAGCAATC TGACAAATGG CATCCAGGAG





44701
CTGGGCCCCT ACACCCTGGA CCGGAACAGT CTCTACGTCA ATGGTTTCAC





44751
CCATCGGAGC TCTGGGCTCA CCACCAGCAC TCCTTGGACT TCCACAGTTG





44801
ACCTTGGAAC CTCAGGGACT CCATCCCCCG TCCCCAGCCC CACAACTGCT





44851
GGCCCTCTCC TGGTGCCATT CACCCTCAAC TTCACCATCA CCAACCTGCA





44901
GTATGAGGAG GACATGCATC GCCCTGGTTC CAGGAGGTTC AACACCACGG





44951
AGAGGGTTCT GCAGGGTCTG CTCACGCCCT TGTTCAAGAA CACCAGTGTT





45001
GGCCCTCTGT ACTCTGGCTG CAGACTGACC TTGCTCAGAC CTGAGAAGCA





45051
AGAGGCAGCC ACTGGAGTGG ACACCATCTG TACCCACCGC GTTGATCCCA





45101
TCGGACCTGG ACTGGACAGA GAGCGGCTAT ACTGGGAGCT GAGCCAGCTG





45151
ACCAACAGCA TCACAGAGCT GGGACCCTAC ACCCTGGATA GGGACAGTCT





45201
CTATGTCAAT GGCTTCAACC CTTGGAGCTC TGTGCCAACC ACCAGCACTC





45251
CTGGGACCTC CACAGTGCAC CTGGCAACCT CTGGGACTCC ATCCTCCCTG





45301
CCTGGCCACA CAGCCCCTGT CCCTCTCTTG ATACCATTCA CCCTCAACTT





45351
TACCATCACC GACCTGCATT ATGAAGAAAA CATGCAACAC CCTGGTTCCA





45401
GGAAGTTCAA CACCACGGAG AGGGTTCTGC AGGGTCTGCT CAAGCCCTTG





45451
TTCAAGAGCA CCAGCGTTGG CCCTCTGTAC TCTGGCTGCA GACTGACCTT





45501
GCTCAGACCT GAGAAACATG GGGCAGCCAC TGGAGTGGAC GCCATCTGCA





45551
CCCTCCGCCT TGATCCCACT GGTCCTGGAC TGGACAGAGA GCGGCTATAC





45601
TGGGAGCTGA GCCAGCTGAC CAACAGCGTT ACAGAGCTGG GCCCCTACAC





45651
CCTGGACAGG GACAGTCTCT ATGTCAATGG CTTCACCCAT CGGAGCTCTG





45701
TGCCAACCAC CAGTATTCCT GGGACCTCTG CAGTGCACCT GGAAACCTCT





45751
GGGACTCCAG CCTCCCTCCC TGGCCACACA GCCCCTGGCC CTCTCCTGGT





45801
GCCATTCACC CTCAACTTCA CTATCACCAA CCTGCAGTAT GAGGAGGACA





45851
TGCGTCACCC TGGTTCCAGG AAGTTCAGCA CCACGGAGAG AGTCCTGCAG





45901
GGTCTGCTCA AGCCCTTGTT CAAGAACACC AGTGTCAGCT CTCTGTACTC





45951
TGGTTGCAGA CTGACCTTGC TCAGGCCTGA GAAGGATGGG GCAGCCACCA





46001
GAGTGGATGC TGTCTGCACC CATCGTCCTG ACCCCAAAAG CCCTGGACTG





46051
GACAGAGAGC GGCTGTACTG GAAGCTGAGC CAGCTGACCC ACGGCATCAC





46101
TGAGCTGGGC CCCTACACCC TGGACAGGCA CAGTCTCTAT GTCAATGGTT





46151
TCACCCATCA GAGCTCTATG ACGACCACCA GAACTCCTGA TACCTCCACA





46201
ATGCACCTGG CAACCTCGAG AACTCCAGCC TCCCTGTCTG GACCTACGAC





46251
CGCCAGCCCT CTCCTGGTGC TATTCACAAT TAACTTCACC ATCACTAACC





46301
TGCGGTATGA GGAGAACATG CATCACCCTG GCTCTAGAAA GTTTAACACC





46351
ACGGAGAGAG TCCTTCAGGG TCTGCTCAGG CCTGTGTTCA AGAACACCAG





46401
TGTTGGCCCT CTGTACTCTG GCTGCAGACT GACCACGCTC AGGCCCAAGA





46451
AGGATGGGGC AGCCACCAAA GTGGATGCCA TCTGCACCTA CCGCCCTGAT





46501
CCCAAAAGCC CTGGACTGGA CAGAGAGCAG CTATACTGGG AGCTGAGCCA





46551
GCTAACCCAC AGCATCACTG AGCTGGGCCC CTACACCCAG GACAGGGACA





46601
GTCTCTATGT CAATGGCTTC ACCCATCGGA GCTCTGTGCC AACCACCAGT





46651
ATTCCTGGGA CCTCTGCAGT GCACCTGGAA ACCTCTGGGA CTCCAGCCTC





46701
CCTCCCTGGC CACACAGCCC CTGGCCCTCT CCTGGTGCCA TTCACCCTCA





46751
ACTTCACTAT CACCAACCTG CAGTATGAGG AGGACATGCG TCACCCTGGT





46801
TCCAGGAAGT TCAACACCAC GGAGAGAGTC CTGCAGGGTC TGCTCAAGCC





46851
CTTGTTCAAG AGCACCAGTG TTGGCCCTCT GTACTCTGGC TGCAGACTGA





46901
CCTTGCTCAG GCCTGAAAAA CGTGGGGCAG CCACCGGCGT GGACACCATC





46951
TGCACTCACC GCCTTGACCC TCTAAACCCA GGACTGGACA GAGAGCAGCT





47001
ATACTGGGAG CTGAGCAAAC TGACCCGTGG CATCATCGAG CTGGGCCCCT





47051
ACCTCCTGGA CAGAGGCAGT CTCTATGTCA ATGGTTTCAC CCATCGGACC





47101
TCTGTGCCCA CCACCAGCAC TCCTGGGACC TCCACAGTGG ACCTTGGAAC





47151
CTCAGGGACT CCATTCTCCC TCCCAAGCCC CGCANCNNCT GNCCCTCTCC





47201
TGNTNCCNTT CACCNTCAAC TTNACCATCA CCAACCTGCA NTANGNGGAN





47251
NACATGCNNC NCCCNGGNTC CAGGAAGTTC AACACCACNG AGAGGGTCCT





47301
GCAGACTCTG CTTGGTCCTA TGTTCAAGAA CACCAGTGTT GGCCTTCTGT





47351
ACTCTGGCTG CAGACTGACC TTGCTCAGGT CCGAGAAGGA TGGAGCAGCC





47401
ACTGGAGTGG ATGCCATCTG CACCCACCGT CTTGACCCCA AAAGCCCTGG





47451
AGTGGACAGG GAGCAACTAT ACTGGGAGCT GAGCCAGCTG ACCAATGGCA





47501
TTAAAGAACT GGGCCCCTAC ACCCTGGACA GGAACAGTCT CTATGTCAAT





47551
GGGTTCACCC ATTGGATCCC TGTGCCCACC AGCAGCACTC CTGGGACCTC





47601
CACAGTGGAC CTTGGGTCAG GGACTCCATC CTCCCTCCCC AGCCCCACAA





47651
CTGCTGGCCC TCTCCTGGTG CCGTTCACCC TCAACTTCAC CATCACCAAC





47701
CTGAAGTACG AGGAGGACAT GCATTGCCCT GGCTCCAGGA AGTTCAACAC





47751
CACAGAGAGA GTCCTGCAGA GTCTGCTTGG TCCCATGTTC AAGAACACCA





47801
GTGTTGGCCC TCTGTACTCT GGCTGCAGAC TGACCTTGCT CAGGTCCGAG





47851
AAGGATGGAG CAGCCACTGG AGTGGATGCC ATCTGCACCC ACCGTCTTGA





47901
CCCCAAAAGC CCTGGAGTGG ACAGGGAGCA GCTATACTGG GAGCTGAGCC





47951
AGCTGACCAA TGGCATCAAA GAGCTGGGTC CCTACACCCT GGACAGAAAC





48001
AGTCTCTATG TCAATGGTTT CACCCATCAG ACCTCTGCGC CCAACACCAG





48051
CACTCCTGGG ACCTCCACAG TGGACCTTGG GACCTCAGGG ACTCCATCCT





48101
CCCTCCCCAG CCCTACANCN NCTGNCCCTC TCCTGNTNCC NTTCACCNTC





48151
AACTTNACCA TCACCAACCT GCANTANGNG GANNACATGC NNCNCCCNGG





48201
NTCCAGGAAG TTCAACACCA CNGAGNGNGT NCTGCAGGGT CTGCTNNNNC





48251
CCNTNTTCAA GAACNCCAGT GTNGGCCNTC TGTACTCTGG CTGCAGACTG





48301
ACCTNNCTCA GGNCNGAGAA GNATGGNGCA GCCACTGGAN TGGATGCCAT





48351
CTGCANCCAC CNNCNTNANC CCAAAAGNCC TGGACTGNAC AGNGAGCNGC





48401
TNTACTGGGA GCTNAGCCAN CTGACCAANN NCATCNNNGA GCTGGGNCCC





48451
TACACCCTGG ACAGGNACAG TCTCTATGTC AATGGTTTCA CCCATTGGAT





48501
CCCTGTGCCC ACCAGCAGCA CTCCTGGGAC CTCCACAGTG GACCTTGGGT





48551
CAGGGACTCC ATCCTCCCTC CCCAGCCCCA CAACTGCTGG CCCTCTCCTG





48601
GTGCCGTTCA CCCTCAACTT CACCATCACC AACCTGAAGT ACGAGGAGGA





48651
CATGCATTGC CCTGGCTCCA GGAAGTTCAA CACCACAGAG AGAGTCCTGC





48701
AGAGTCTGCT TGGTCCCATG TTCAAGAACA CCAGTGTTGG CCCTCTGTAC





48751
TCTGGCTGCA GACTGACCTC GCTCAGGTCC GAGAAGGATG GAGCAGCCAC





48801
TGGAGTGGAT GCCATCTGCA CCCACCGTGT TGACCCCAAA AGCCCTGGAG





48851
TGGACAGGGA GCAGCTATAC TGGGAGCTGA GCCAGCTGAC CAATGGCATC





48901
AAAGAGCTGG GTCCCTACAC CCTGGACAGA AACAGTCTCT ATGTCAATGG





48951
TTTCACCCAT CAGACCTCTG CGCCCAACAC CAGCACTCCT GGGACCTCCA





49001
CAGTGNACNT NGGNACCTCN GGGACTCCAT CCTCCNTCCC CNGCCNCACA





49051
TCTGCTGGCC CTCTCCTGGT GCCATTCACC CTCAACTTCA CCATCACCAA





49101
CCTGCAGTAC GAGGAGGACA TGCATCACCC AGGCTCCAGG AAGTTCAACA





49151
CCACGGAGCG GGTCCTGCAG GGTCTGCTTG GTCCCATGTT CAAGAACACC





49201
AGTGTCGGCC TTCTGTACTC TGGCTGCAGA CTGACCTTGC TCAGGCCTGA





49251
GAAGAATGGG GCAACCACTG GAATGGATGC CATCTGCACC CACCGTCTTG





49301
ACCCCAAAAG CCCTGGACTG NACAGNGAGC NGCTNTACTG GGAGCTNAGC





49351
CANCTGACCA ANNNCATCNN NGAGCTGGGN CCCTACACCC TGGACAGGNA





49401
CAGTCTCTAT GTCAATGGTT TCACCCATCN GANCTCTGNG CCCACCACCA





49451
GCACTCCTGG GACCTCCACA GTGNACNTNG GNACCTCNGG GACTCCATCC





49501
TCCNTCCCCN GCCNCACANC NNCTGNCCCT CTCCTGNTNC CNTTCACCNT





49551
CAACTTNACC ATCACCAACC TGCANTANGN GGANNACATG CNNCNCCCNG





49601
GNTCCAGGAA GTTCAACACC ACNGAGAGGG TTCTGCAGGG TCTGCTCAAA





49651
CCCTTGTTCA GGAATAGCAG TCTGGAATAC CTCTATTCAG GCTGCAGACT





49701
AGCCTCACTC AGGCCAGAGA AGGATAGCTC AGCCATGGCA GTGGATGCCA





49751
TCTGCACACA TCGCCCTGAC CCTGAAGACC TCGGACTGGA CAGAGAGCGA





49801
CTGTACTGGG AGCTGAGCAA TCTGACAAAT GGCATCCAGG AGCTGGGCCC





49851
CTACACCCTG GACCGGAACA GTCTCTATGT CAATGGTTTC ACCCATCGAA





49901
GCTCTATGCC CACCACCAGC ACTCCTGGGA CCTCCACAGT GGATGTGGGA





49951
ACCTCAGGGA CTCCATCCTC CAGCCCCAGC CCCACGACTG CTGGCCCTCT





50001
CCTGATACCA TTCACCCTCA ACTTCACCAT CACCAACCTG CAGTATGGGG





50051
AGGACATGGG TCACCCTGGC TCCAGGAAGT TCAACACCAC AGAGAGGGTC





50101
CTGCAGGGTC TGCTTGGTCC CATATTCAAG AACACCAGTG TTGGCCCTCT





50151
GTACTCTGGC TGCAGACTGA CCTCTCTCAG GTCTGAGAAG GATGGAGCAG





50201
CCACTGGAGT GGATGCCATC TGCATCCATC ATCTTGACCC CAAAAGCCCT





50251
GGACTCAACA GAGAGCGGCT GTACTGGGAG CTGAGCCAAC TGACCAATGG





50301
CATCAAAGAG CTGGGCCCCT ACACCCTGGA CAGGAACAGT CTCTATGTCA





50351
ATGGTTTCAC CCATCGGACC TCTGTGCCCA CCACCAGCAC TCCTGGGACC





50401
TCCACAGTGG ACCTTGGAAC CTCAGGGACT CCATTCTCCC TCCCAAGCCC





50451
CGCAACTGCT GGCCCTCTCC TGGTGCTGTT CACCCTCAAC TTCACCATCA





50501
CCAACCTGAA GTATGAGGAG GACATGCATC GCCCTGGCTC CAGGAAGTTC





50551
AACACCACTG AGAGGGTCCT GCAGACTCTG CTTGGTCCTA TGTTCAAGAA





50601
CACCAGTGTT GGCCTTCTGT ACTCTGGCTG CAGACTGACC TTGCTCAGGT





50651
CCGAGAAGGA TGGAGCAGCC ACTGGAGTGG ATGCCATCTG CACCCACCGT





50701
CTTGACCCCA AAAGCCCTGG ACTGNACAGN GAGCNGCTNT ACTGGGAGCT





50751
NAGCCANCTG ACCAANNNCA TCNNNGAGCT GGGNCCCTAC ACCCTGGACA





50801
GGNACAGTCT CTATGTCAAT GGTTTCACCC ATCNGANCTC TGNGCCCACC





50851
ACCAGCACTC CTGGGACCTC CACAGTGNAC NTNGGNACCT CNGGGACTCC





50901
ATCCTCCNTC CCCNGCCNCA CANCNNCTGN CCCTCTCCTG NTNCCNTTCA





50951
CCNTCAACTT NACCATCACC AACCTGCANT ANGNGGANNA CATGCNNCNC





51001
CCNGGNTCCA GGAAGTTCAA CACCACNGAG AGAGTCCTTC AGGGTCTGCT





51051
CAGGCCTGTG TTCAAGAACA CCAGTGTTGG CCCTCTGTAC TCTGGCTGCA





51101
GACTGACCTT GCTCAGGCCC AAGAAGGATG GGGCAGCCAC CAAAGTGGAT





51151
GCCATCTGCA CCTACCGCCC TGATCCCAAA AGCCCTGGAC TGGACAGAGA





51201
GCAGCTATAC TGGGAGCTGA GCCAGCTAAC CCACAGCATC ACTGAGCTGG





51251
GCCCCTACAC CCAGGACAGG GACAGTCTCT ATGTCAATGG CTTCACCCAT





51301
CGGAGCTCTG TGCCAACCAC CAGTATTCCT GGGACCTCTG CAGTGCACCT





51351
GGAAACCACT GGGACTCCAT CCTCCTTCCC CGGCCACACA GAGCCTGGCC





51401
CTCTCCTGAT ACCATTCACT TTCAACTTTA CCATCACCAA CCTGCGTTAT





51451
GAGGAAAACA TGCAACACCC TGGTTCCAGG AAGTTCAACA CCACGGAGAG





51501
GGTTCTGCAG GGTCTGCTCA CGCCCTTGTT CAAGAACACC AGTGTTGGCC





51551
CTCTGTACTC TGGCTGCAGA CTGACCTTGC TCAGACCTGA GAAGCAGGAG





51601
GCAGCCACTG GAGTGGACAC CATCTGTACC CACCGCGTTG ATCCCATCGG





51651
ACCTGGACTG GACAGAGAGC GGCTATACTG GGAGCTGAGC CAGCTGACCA





51701
ACAGCATCAC AGAGCTGGGA CCCTACACCC TGGATAGGGA CAGTCTCTAT





51751
GTCGATGGCT TCAACCCTTG GAGCTCTGTG CCAACCACCA GCACTCCTGG





51801
GACCTCCACA GTGCACCTGG CAACCTCTGG GACTCCATCC CCCCTGCCTG





51851
GCCACACAGC CCCTGTCCCT CTCTTGATAC CATTCACCCT CAACTTTACC





51901
ATCACCGACC TGCATTATGA AGAAAACATG CAACACCCTG GTTCCAGGAA





51951
GTTCAACACC ACGGAGAGGG TTCTGCAGGG TCTGCTCAAG CCCTTGTTCA





52001
AGAGCACCAG CGTTGGCCCT CTGTACTCTG GCTGCAGACT GACCTTGCTC





52051
AGACCTGAGA AACATGGGGC AGCCACTGGA GTGGACGCCA TCTGCACCCT





52101
CCGCCTTGAT CCCACTGGTC CTGGACTGGA CAGAGAGCGG CTATACTGGG





52151
AGCTGAGCCA GCTGACCAAC AGCATCACAG AGCTGGGACC CTACACCCTG





52201
GATAGGGACA GTCTCTATGT CAATGGCTTC AACCCTTGGA GCTCTGTGCC





52251
AACCACCAGC ACTCCTGGGA CCTCCACAGT GCACCTGGCA ACCTCTGGGA





52301
CTCCATCCTC CCTGCCTGGC CACACAACTG CTGGCCCTCT CCTGGTGCCG





52351
TTCACCCTCA ACTTCACCAT CACCAACCTG AAGTACGAGG AGGACATGCA





52401
TTGCCCTGGC TCCAGGAAGT TCAACACCAC AGAGAGAGTC CTGCAGAGTC





52451
TGCATGGTCC CATGTTCAAG AACACCAGTG TTGGCCCTCT GTACTCTGGC





52501
TGCAGACTGA CCTTGCTCAG GTCCGAGAAG GATGGAGCAG CCACTGGAGT





52551
GGATGCCATC TGCACCCACC GTCTTGACCC CAAAAGCCCT GGACTGNACA





52601
GNGAGCNGCT NTACTGGGAG CTNAGCCANC TGACCAANNN CATCNNNGAG





52651
CTGGGNCCCT ACACCCTGGA CAGGNACAGT CTCTATGTCA ATGGTTTCAC





52701
CCATCNGANC TCTGNGCCCA CCACCAGCAC TCCTGGGACC TCCACAGTGN





52751
ACNTNGGNAC CTCNGGGACT CCATCCTCCN TCCCCNGCCN CACANCNNCT





52801
GNCCCTCTCC TGNTNCCNTT CACCNTCAAC TTNACCATCA CCAACCTGCA





52851
NTANGNGGAN NACATGCNNC NCCCNGGNTC CAGGAAGTTC AACACCACNG





52901
AGNGNGTNCT GCAGGGTCTG CTNNNNCCCN TNTTCAAGAA CNCCAGTGTN





52951
GGCCNTCTGT ACTCTGGCTG CAGACTGACC TNNCTCAGGN CNGAGAAGNA





53001
TGGNGCAGCC ACTGGANTGG ATGCCATCTG CANCCACCNN CNTNANCCCA





53051
AAAGNCCTGG ACTGNACAGN GAGCNGCTNT ACTGGGAGCT NAGCCANCTG





53101
ACCAACAGCA TCACAGAGCT GGGACCCTAC ACCCTGGATA GGGACAGTCT





53151
CTATGTCAAT GGTTTCACCC ATCGAAGCTC TATGCCCACC ACCAGTATTC





53201
CTGGGACCTC TGCAGTGCAC CTGGAAACCT CTGGGACTCC AGCCTCCCTC





53251
CCTGGCCACA CAGCCCCTGG CCCTCTCCTG GTGCCATTCA CCCTCAACTT





53301
CACTATCACC AACCTGCAGT ATGAGGAGGA CATGCGTCAC CCTGGTTCCA





53351
GGAAGTTCAA CACCACGGAG AGAGTCCTGC AGGGTCTGCT CAAGCCCTTG





53401
TTCAAGAGCA CCAGTGTTGG CCCTCTGTAC TCTGGCTGCA GACTGACCTT





53451
GCTCAGGCCT GAAAAACGTG GGGCAGCCAC CGGCGTGGAC ACCATCTGCA





53501
CTCACCGCCT TGACCCTCTA AACCCTGGAC TGNACAGNGA GCNGCTNTAC





53551
TGGGAGCTNA GCCANCTGAC CAANNNCATC NNNGAGCTGG GNCCCTACAC





53601
CCTGGACAGG NACAGTCTCT ATGTCAATGG TTTCACCCAT CNGANCTCTG





53651
NGCCCACCAC CAGCACTCCT GGGACCTCCA CAGTGNACNT NGGNACCTCN





53701
GGGACTCCAT CCTCCNTCCC CNGCCNCACA NCNNCTGNCC CTCTCCTGNT





53751
NCCNTTCACC NTCAACTTNA CCATCACCAA CCTGCANTAN GNGGANNACA





53801
TGCNNCNCCC NGGNTCCAGG AAGTTCAACA CCACNGAGNG NGTNCTGCAG





53851
GGTCTGCTNN NNCCCNTNTT CAAGAACNCC AGTGTNGGCC NTCTGTACTC





53901
TGGCTGCAGA CTGACCTNNC TCAGGNCNGA GAAGNATGGN GCAGCCACTG





53951
GANTGGATGC CATCTGCANC CACCNNCNTN ANCCCAAAAG NCCTGGACTG





54001
NACAGNGAGC NGCTNTACTG GGAGCTNAGC CANCTGACCA ANNNCATCNN





54051
NGAGCTGGGN CCCTACACCC TGGACAGGNA CAGTCTCTAT GTCAATGGTT





54101
TTCACCCTCG GAGCTCTGTG CCAACCACCA GCACTCCTGG GACCTCCACA





54151
GTGCACCTGG CAACCTCTGG GACTCCATCC TCCCTGCCTG GCCACACAGC





54201
CCCTGTCCCT CTCTTGATAC CATTCACCCT CAACTTTACC ATCACCAACC





54251
TGCATTATGA AGAAAACATG CAACACCCTG GTTCCAGGAA GTTCAACACC





54301
ACGGAGCGGG TCCTGCAGGG TCTGCTTGGT CCCATGTTCA AGAACACAAG





54351
TGTCGGCCTT CTGTACTCTG GCTGCAGACT GACCTTGCTC AGGCCTGAGA





54401
AGAATGGGGC AGCCACTGGA ATGGATGCCA TCTGCAGCCA CCGTCTTGAC





54451
CCCAAAAGCC CTGGACTGNA CAGNGAGCNG CTNTACTGGG AGCTNAGCCA





54501
NCTGACCAAN NNCATCNNNG AGCTGGGNCC CTACACCCTG GACAGGNACA





54551
GTCTCTATGT CAATGGTTTC ACCCATCNGA NCTCTGNGCC CACCACCAGC





54601
ACTCCTGGGA CCTCCACAGT GNACNTNGGN ACCTCNGGGA CTCCATCCTC





54651
CNTCCCCNGC CNCACANCNN CTGNCCCTCT CCTGNTNCCN TTCACCNTCA





54701
ACTTNACCAT CACCAACCTG CANTANGNGG ANNACATGCN NCNCCCNGGN





54751
TCCAGGAAGT TCAACACCAC NGAGNGNGTN CTGCAGGGTC TGCTNNNNCC





54801
CNTNTTCAAG AACNCCAGTG TNGGCCNTCT GTACTCTGGC TGCAGACTGA





54851
CCTNNCTCAG GNCNGAGAAG NATGGNGCAG CCACTGGANT GGATGCCATC





54901
TGCANCCACC NNCNTNANCC CAAAAGNCCT GGACTGNACA GNGAGCNGCT





54951
NTACTGGGAG CTNAGCCANC TGACCAANNN CATCNNNGAG CTGGGNCCCT





55001
ACACCCTGGA CAGGNACAGT CTCTATGTCA ATGGTTTCAC CCATCAGAAC





55051
TCTGTGCCCA CCACCAGTAC TCCTGGGACC TCCACAGTGT ACTGGGCAAC





55101
CACTGGGACT CCATCCTCCT TCCCCGGCCA CACAGAGCCT GGCCCTCTCC





55151
TGATACCATT CACTTTCAAC TTTACCATCA CCAACCTGCA TTATGAGGAA





55201
AACATGCAAC ACCCTGGTTC CAGGAAGTTC AACACCACGG AGAGGGTTCT





55251
GCAGGGTCTG CTCACGCCCT TGTTCAAGAA CACCAGTGTT GGCCCTCTGT





55301
ACTCTGGCTG CAGACTGACC TTGCTCAGAC CTGAGAAGCA GGAGGCAGCC





55351
ACTGGAGTGG ACACCATCTG TACCCACCGC GTTGATCCCA TCGGACCTGG





55401
ACTGNACAGN GAGCNGCTNT ACTGGGAGCT NAGCCANCTG ACCAANNNCA





55451
TCNNNGAGCT GGGNCCCTAC ACCCTGGACA GGNACAGTCT CTATGTCAAT





55501
GGTTTCACCC ATCNGANCTC TGNGCCCACC ACCAGCACTC CTGGGACCTC





55551
CACAGTGNAC NTNGGNACCT CNGGGACTCC ATCCTCCNTC CCCNGCCNCA





55601
CANCNNCTGN CCCTCTCCTG NTNCCNTTCA CCNTCAACTT NACCATCACC





55651
AACCTGCANT ANGNGGANNA CATGCNNCNC CCNGGNTCCA GGAAGTTCAA





55701
CACCACNGAG NGNGTNCTGC AGGGTCTGCT NNNNCCCNTN TTCAAGAACN





55751
CCAGTGTNGG CCNTCTGTAC TCTGGCTGCA GACTGACCTN NCTCAGGNCN





55801
GAGAAGNATG GNGCAGCCAC TGGANTGGAT GCCATCTGCA NCCACCNNCN





55851
TNANCCCAAA AGNCCTGGAC TGNACAGNGA GCNGCTNTAC TGGGAGCTNA





55901
GCCANCTGAC CAANNNCATC NNNGAGCTGG GNCCCTACAC CCTGGACAGG





55951
NACAGTCTCT ATGTCAATGG TTTCACCCAT CGGAGCTCTG TGCCAACCAC





56001
CAGCAGTCCT GGGACCTCCA CAGTGCACCT GGCAACCTCT GGGACTCCAT





56051
CCTCCCTGCC TGGCCACACA GCCCCTGTCC CTCTCTTGAT ACCATTCACC





56101
CTCAACTTTA CCATCACCAA CCTGCATTAT GAAGAAAACA TGCAACACCC





56151
TGGTTCCAGG AAGTTCAACA CCACGGAGAG GGTTCTGCAG GGTCTGCTCA





56201
AGCCCTTGTT CAAGAGCACC AGTGTTGGCC CTCTGTACTC TGGCTGCAGA





56251
CTGACCTTGC TCAGACCTGA GAAACATGGG GCAGCCACTG GAGTGGACGC





56301
CATCTGCACC CTCCGCCTTG ATCCCACTGG TCCTGGACTG NACAGNGAGC





56351
NGCTNTACTG GGAGCTNAGC CANCTGACCA ANNNCATCNN NGAGCTGGGN





56401
CCCTACACCC TGGACAGGNA CAGTCTCTAT GTCAATGGTT TCACCCATCN





56451
GANCTCTGNG CCCACCACCA GCACTCCTGG GACCTCCACA GTGNACNTNG





56501
GNACCTCNGG GACTCCATCC TCCNTCCCCN GCCNCACANC NNCTGNCCCT





56551
CTCCTGNTNC CNTTCACCNT CAACTTNACC ATCACCAACC TGCANTANGN





56601
GGANNACATG CNNCNCCCNG GNTCCAGGAA GTTCAACACC ACNGAGNGNG





56651
TNCTGCAGGG TCTGCTNNNN CCCNTNTTCA AGAACNCCAG TGTNGGCCNT





56701
CTGTACTCTG GCTGCAGACT GACCTNNCTC AGGNCNGAGA AGNATGGNGC





56751
AGCCACTGGA NTGGATGCCA TCTGCANCCA CCNNCNTNAN CCCAAAAGNC





56801
CTGGACTGNA CAGNGAGCNG CTNTACTGGG AGCTNAGCCA NCTGACCAAN





56851
NNCATCNNNG AGCTGGGNCC CTACACCCTG GACAGGNACA GTCTCTATGT





56901
CAATGGTTTC ACCCATCGGA CCTCTGTGCC CACCACCAGC ACTCCTGGGA





56951
CCTCCACAGT GCACCTGGCA ACCTCTGGGA CTCCATCCTC CCTGCCTGGC





57001
CACACAGCCC CTGTCCCTCT CTTGATACCA TTCACCCTCA ACTTTACCAT





57051
CACCAACCTG CAGTATGAGG AGGACATGCA TCGCCCTGGA TCTAGGAAGT





57101
TCAACACCAC AGAGAGGGTC CTGCAGGGTC TGCTTAGTCC CATTTTCAAG





57151
AACTCCAGTG TTGGCCCTCT GTACTCTGGC TGCAGACTGA CCTCTCTCAG





57201
GCCCGAGAAG GATGGGGCAG CAACTGGAAT GGATGCTGTC TGCCTCTACC





57251
ACCCTAATCC CAAAAGACCT GGGCTGGACA GAGAGCAGCT GTACTGCGAG





57301
CTAAGCCAGC TGACCCACAA CATCACTGAG CTGGGCCCCT ACAGCCTGGA





57351
CAGGGACAGT CTCTATGTCA ATGGTTTCAC CCATCAGAAC TCTGTGCCCA





57401
CCACCAGTAC TCCTGGGACC TCCACAGTGT ACTGGGCAAC CACTGGGACT





57451
CCATCCTCCT TCCCCGGCCA CACANCNNCT GNCCCTCTCC TGNTNCCNTT





57501
CACCNTCAAC TTNACCATCA CCAACCTGCA NTANGNGGAN NACATGCNNC





57551
NCCCNGGNTC CAGGAAGTTC AACACCACNG AGNGNGTNCT GCAGGGTCTG





57601
CTNNNNCCCN TNTTCAAGAA CNCCAGTGTN GGCCNTCTGT ACTCTGGCTG





57651
CAGACTGACC TNNCTCAGGN CNGAGAAGNA TGGNGCAGCC ACTGGANTGG





57701
ATGCCATCTG CANCCACCNN CNTNANCCCA AAAGNCCTGG ACTGNACAGN





57751
GAGCNGCTNT ACTGGGAGCT NAGCCANCTG ACCAANNNCA TCNNNGAGCT





57801
GGGNCCCTAC ACCCTGGACA GGNACAGTCT CTATGTCAAT GGTTTCACCC





57851
ATTGGAGCTC TGGGCTCACC ACCAGCACTC CTTGGACTTC CACAGTTGAC





57901
CTTGGAACCT CAGGGACTCC ATCCCCCGTC CCCAGCCCCA CAACTGCTGG





57951
CCCTCTCCTG GTGCCATTCA CCCTAAACTT CACCATCACC AACCTGCAGT





58001
ATGAGGAGGA CATGCATCGC CCTGGATCTA GGAAGTTCAA CGCCACAGAG





58051
AGGGTCCTGC AGGGTCTGCT TAGTCCCATA TTCAAGAACA CCAGTGTTGG





58101
CCCTCTGTAC TCTGGCTGCA GACTGACCTT GCTCAGACCT GAGAAGCAGG





58151
AGGCAGCCAC TGGAGTGGAC ACCATCTGTA CCCACCGCGT TGATCCCATC





58201
GGACCTGGAC TGNACAGNGA GCNGCTNTAC TGGGAGCTNA GCCANCTGAC





58251
CAANNNCATC NNNGAGCTGG GNCCCTACAC CCTGGACAGG NACAGTCTCT





58301
ATGTCAATGG TTTCACCCAT CNGANCTCTG NGCCCACCAC CAGCACTCCT





58351
GGGACCTCCA CAGTGNACNT NGGNACCTCN GGGACTCCAT CCTCCNTCCC





58401
CNGCCNCACA NCNNCTGNCC CTCTCCTGNT NCCNTTCACC NTCAACTTNA





58451
CCATCACCAA CCTGCANTAN GNGGANNACA TGCNNCNCCC NGGNTCCAGG





58501
AAGTTCAACA CCACNGAGNG NGTNCTGCAG GGTCTGCTNN NNCCCNTNTT





58551
CAAGAACNCC AGTGTNGGCC NTCTGTACTC TGGCTGCAGA CTGACCTNNC





58601
TCAGGNCNGA GAAGNATGGN GCAGCCACTG GANTGGATGC CATCTGCANC





58651
CACCNNCNTN ANCCCAAAAG NCCTGGACTG NACAGNGAGC NGCTNTACTG





58701
GGAGCTNAGC CANCTGACCA ANNNCATCNN NGAGCTGGGN CCCTACACCC





58751
TGGACAGGNA CAGTCTCTAT GTCAATGGTT TCACCCATCG GAGCTTTGGG





58801
CTCACCACCA GCACTCCTTG GACTTCCACA GTTGACCTTG GAACCTCAGG





58851
GACTCCATCC CCCGTCCCCA GCCCCACAAC TGCTGGCCCT CTCCTGGTGC





58901
CATTCACCCT AAACTTCACC ATCACCAACC TGCAGTATGA GGAGGACATG





58951
CATCGCCCTG GCTCCAGGAA GTTCAACACC ACGGAGAGGG TCCTTCAGGG





59001
TCTGCTTACG CCCTTGTTCA GGAACACCAG TGTCAGCTCT CTGTACTCTG





59051
GTTGCAGACT GACCTTGCTC AGGCCTGAGA AGGATGGGGC AGCCACCAGA





59101
GTGGATGCTG TCTGCACCCA TCGTCCTGAC CCCAAAAGCC CTGGACTGNA





59151
CAGNGAGCNG CTNTACTGGG AGCTNAGCCA NCTGACCAAN NNCATCNNNG





59201
AGCTGGGNCC CTACACCCTG GACAGGNACA GTCTCTATGT CAATGGTTTC





59251
ACCCATCNGA NCTCTGNGCC CACCACCAGC ACTCCTGGGA CCTCCACAGT





59301
GNACNTNGGN ACCTCNGGGA CTCCATCCTC CNTCCCCNGC CNCACANCNN





59351
CTGNCCCTCT CCTGNTNCCN TTCACCNTCA ACTTNACCAT CACCAACCTG





59401
CANTANGNGG ANNACATGCN NCNCCCNGGN TCCAGGAAGT TCAACACCAC





59451
NGAGNGNGTN CTGCAGGGTC TGCTNNNNCC CNTNTTCAAG AACNCCAGTG





59501
TNGGCCNTCT GTACTCTGGC TGCAGACTGA CCTNNCTCAG GNCNGAGAAG





59551
NATGGNGCAG CCACTGGANT GGATGCCATC TGCANCCACC NNCNTNANCC





59601
CAAAAGNCCT GGACTGNACA GNGAGCNGCT NTACTGGGAG CTNAGCCANC





59651
TGACCAANNN CATCNNNGAG CTGGGNCCCT ACACCCTGGA CAGGNACAGT





59701
CTCTATGTCA ATGGTTTCAC CCATTGGATC CCTGTGCCCA CCAGCAGCAC





59751
TCCTGGGACC TCCACAGTGG ACCTTGGGTC AGGGACTCCA TCCTCCCTCC





59801
CCAGCCCCAC AACTGCTGGC CCTCTCCTGG TACCATTCAC CCTCAACTTC





59851
ACCATCACCA ACCTGCAGTA TGGGGAGGAC ATGGGTCACC CTGGCTCCAG





59901
GAAGTTCAAC ACCACAGAGA GGGTCCTGCA GGGTCTGCTT GGTCCCATAT





59951
TCAAGAACAC CAGTGTTGGC CCTCTGTACT CTGGCTGCAG ACTGACCTCT





60001
CTCAGGTCCG AGAAGGATGG AGCAGCCACT GGAGTGGATG CCATCTGCAT





60051
CCATCATCTT GACCCCAAAA GCCCTGGACT GNACAGNGAG CNGCTNTACT





60101
GGGAGCTNAG CCANCTGACC AANNNCATCN NNGAGCTGGG NCCCTACACC





60151
CTGGACAGGN ACAGTCTCTA TGTCAATGGT TTCACCCATC NGANCTCTGN





60201
GCCCACCACC AGCACTCCTG GGACCTCCAC AGTGNACNTN GGNACCTCNG





60251
GGACTCCATC CTCCNTCCCC NGCCNCACAN CNNCTGNCCC TCTCCTGNTN





60301
CCNTTCACCN TCAACTTNAC CATCACCAAC CTGCANTANG NGGANNACAT





60351
GCNNCNCCCN GGNTCCAGGA AGTTCAACAC CACNGAGNGN GTNCTGCAGG





60401
GTCTGCTNNN NCCCNTNTTC AAGAACNCCA GTGTNGGCCN TCTGTACTCT





60451
GGCTGCAGAC TGACCTNNCT CAGGNCNGAG AAGNATGGNG CAGCCACTGG





60501
ANTGGATGCC ATCTGCANCC ACCNNCNTNA NCCCAAAAGN CCTGGACTGN





60551
ACAGNGAGCN GCTNTACTGG GAGCTNAGCC ANCTGACCAA NNNCATCNNN





60601
GAGCTGGGNC CCTACACCCT GGACAGGNAC AGTCTCTATG TCAATGGTTT





60651
CACCCATCAG ACCTTTGCGC CCAACACCAG CACTCCTGGG ACCTCCACAG





60701
TGGACCTTGG GACCTCAGGG ACTCCATCCT CCCTCCCCAG CCCTACATCT





60751
GCTGGCCCTC TCCTGGTGCC ATTCACCCTC AACTTCACCA TCACCAACCT





60801
GCAGTACGAG GAGGACATGC ATCACCCAGG CTCCAGGAAG TTCAACACCA





60851
CGGAGCGGGT CCTGCAGGGT CTGCTTGGTC CCATGTTCAA GAACACCAGT





60901
GTCGGCCTTC TGTACTCTGG CTGCAGACTG ACCTTGCTCA GGCCTGAGAA





60951
GAATGGGGCA GCCACCAGAG TGGATGCTGT CTGCACCCAT CGTCCTGACC





61001
CCAAAAGCCC TGGACTGNAC AGNGAGCNGC TNTACTGGGA GCTNAGCCAN





61051
CTGACCAANN NCATCNNNGA GCTGGGNCCC TACACCCTGG ACAGGNACAG





61101
TCTCTATGTC AATGGTTTCA CCCATCNGAN CTCTGNGCCC ACCACCAGCA





61151
CTCCTGGGAC CTCCACAGTG NACNTNGGNA CCTCNGGGAC TCCATCCTCC





61201
NTCCCCNGCC NCACAGCCCC TGTCCCTCTC TTGATACCAT TCACCCTCAA





61251
CTTTACCATC ACCAACCTGC ATTATGAAGA AAACATGCAA CACCCTGGTT





61301
CCAGGAAGTT CAACACCACG GAGAGGGTTC TGCAGGGTCT GCTCAAGCCC





61351
TTGTTCAAGA GCACCAGCGT TGGCCCTCTG TACTCTGGCT GCAGACTGAC





61401
CTTGCTCAGA CCTGAGAAAC ATGGGGCAGC CACTGGAGTG GACGCCATCT





61451
GCACCCTCCG CCTTGATCCC ACTGGTCCTG GACTGGACAG AGAGCGGCTA





61501
TACTGGGAGC TGAGCCAGCT GACCAACAGC GTTACAGAGC TGGGCCCCTA





61551
CACCCTGGAC AGGGACAGTC TCTATGTCAA TGGCTTCACC CAGCGGAGCT





61601
CTGTGCCAAC CACCAGTATT CCTGGGACCT CTGCAGTGCA CCTGGAAACC





61651
TCTGGGACTC CAGCCTCCCT CCCTGGCCAC ACAGCCCCTG GCCCTCTCCT





61701
GGTGCCATTC ACCCTCAACT TCACTATCAC CAACCTGCAG TATGAGGTGG





61751
ACATGCGTCA CCCTGGTTCC AGGAAGTTCA ACACCACGGA GAGAGTCCTG





61801
CAGGGTCTGC TCAAGCCCTT GTTCAAGAGC ACCAGTGTTG GCCCTCTGTA





61851
CTCTGGCTGC AGACTGACCT TGCTCAGGCC TGAAAAACGT GGGGCAGCCA





61901
CCGGCGTGGA CACCATCTGC ACTCACCGCC TTGACCCTCT AAACCCTGGA





61951
CTGGACAGAG AGCAGCTATA CTGGGAGCTG AGCAAACTGA CCCGTGGCAT





62001
CATCGAGCTG GGCCCCTACC TCCTGGACAG AGGCAGTCTC TATGTCAATG





62051
GTTTCACCCA TCGGAACTTT GTGCCCATCA CCAGCACTCC TGGGACCTCC





62101
ACAGTACACC TAGGAACCTC TGAAACTCCA TCCTCCCTAC CTAGACCCAT





62151
AGTGCCTGGC CCTCTCCTGG TGCCATTCAC CCTCAACTTC ACCATCACCA





62201
ACTTGCAGTA TGAGGAGGCC ATGCGACACC CTGGCTCCAG GAAGTTCAAT





62251
ACCACGGAGA GGGTCCTACA GGGTCTGCTC AGGCCCTTGT TCAAGAATAC





62301
CAGTATCGGC CCTCTGTACT CCAGCTGCAG ACTGACCTTG CTCAGGCCAG





62351
AGAAGGACAA GGCAGCCACC AGAGTGGATG CCATCTGTAC CCACCACCCT





62401
GACCCTCAAA GCCCTGGACT GAACAGAGAG CAGCTGTACT GGGAGCTGAG





62451
CCAGCTGACC CACGGCATCA CTGAGCTGGG CCCCTACACC CTGGACAGGG





62501
ACAGTCTCTA TGTCGATGGT TTCACTCATT GGAGCCCCAT ACCGACCACC





62551
AGCACTCCTG GGACCTCCAT AGTGAACCTG GGAACCTCTG GGATCCCACC





62601
TTCCCTCCCT GAAACTACAN CNNCTGNCCC TCTCCTGNTN CCNTTCACCN





62651
TCAACTTNAC CATCACCAAC CTGCANTANG NGGANNACAT GCNNCNCCCN





62701
GGNTCCAGGA AGTTCAACAC CACNGAGAGG GTTCTGCAGG GTCTGCTCAA





62751
GCCCTTGTTC AAGAGCACCA GTGTTGGCCC TCTGTATTCT GGCTGCAGAC





62801
TGACCTTGCT CAGGCCTGAG AAGGACGGAG TAGCCACCAG AGTGGACGCC





62851
ATCTGCACCC ACCGCCCTGA CCCCAAAATC CCTGGGCTAG ACAGACAGCA





62901
GCTATACTGG GAGCTGAGCC AGCTGACCCA CAGCATCACT GAGCTGGGAC





62951
CCTACACCCT GGATAGGGAC AGTCTCTATG TCAATGGTTT CACCCAGCGG





63001
AGCTCTGTGC CCACCACCAG CACTCCTGGG ACTTTCACAG TACAGCCGGA





63051
AACCTCTGAG ACTCCATCAT CCCTCCCTGG CCCCACAGCC ACTGGCCCTG





63101
TCCTGCTGCC ATTCACCCTC AATTTTACCA TCACTAACCT GCAGTATGAG





63151
GAGGACATGC ATCGCCCTGG CTCCAGGAAG TTCAACACCA CGGAGAGGGT





63201
CCTTCAGGGT CTGCTTATGC CCTTGTTCAA GAACACCAGT GTCAGCTCTC





63251
TGTACTCTGG TTGCAGACTG ACCTTGCTCA GGCCTGAGAA GGATGGGGCA





63301
GCCACCAGAG TGGATGCTGT CTGCACCCAT CGTCCTGACC CCAAAAGCCC





63351
TGGACTGGAC AGAGAGCGGC TGTACTGGAA GCTGAGCCAG CTGACCCACG





63401
GCATCACTGA GCTGGGCCCC TACACCCTGG ACAGGCACAG TCTCTATGTC





63451
AATGGTTTCA CCCATCAGAG CTCTATGACG ACCACCAGAA CTCCTGATAC





63501
CTCCACAATG CACCTGGCAA CCTCGAGAAC TCCAGCCTCC CTGTCTGGAC





63551
CTACGACCGC CAGCCCTCTC CTGGTGCTAT TCACAATTAA CTTCACCATC





63601
ACTAACCTGC GGTATGAGGA GAACATGCAT CACCCTGGCT CTAGAAAGTT





63651
TAACACCACG GAGAGAGTCC TTCAGGGTCT GCTCAGGCCT GTGTTCAAGA





63701
ACACCAGTGT TGGCCCTCTG TACTCTGGCT GCAGACTGAC CTTGCTCAGG





63751
CCCAAGAAGG ATGGGGCAGC CACCAAAGTG GATGCCATCT GCACCTACCG





63801
CCCTGATCCC AAAAGCCCTG GACTGGACAG AGAGCAGCTA TACTGGGAGC





63851
TGAGCCAGCT AACCCACAGC ATCACTGAGC TGGGCCCCTA CACCCTGGAC





63901
AGGGACAGTC TCTATGTCAA TGGTTTCACA CAGCGGAGCT CTGTGCCCAC





63951
CACTAGCATT CCTGGGACCC CCACAGTGGA CCTGGGAACA TCTGGGACTC





64001
CAGTTTCTAA ACCTGGTCCC TCGGCTGCCA GCCCTCTCCT GGTGCTATTC





64051
ACTCTCAACT TCACCATCAC CAACCTGCGG TATGAGGAGA ACATGCAGCA





64101
CCCTGGCTCC AGGAAGTTCA ACACCACGGA GAGGGTCCTT CAGGGCCTGC





64151
TCAGGTCCCT GTTCAAGAGC ACCAGTGTTG GCCCTCTGTA CTCTGGCTGC





64201
AGACTGACTT TGCTCAGGCC TGAAAAGGAT GGGACAGCCA CTGGAGTGGA





64251
TGCCATCTGC ACCCACCACC CTGACCCCAA AAGCCCTAGG CTGGACAGAG





64301
AGCAGCTGTA TTGGGAGCTG AGCCAGCTGA CCCACAATAT CACTGAGCTG





64351
GGCCACTATG CCCTGGACAA CGACAGCCTC TTTGTCAATG GTTTCACTCA





64401
TCGGAGCTCT GTGTCCACCA CCAGCACTCC TGGGACCCCC ACAGTGTATC





64451
TGGGAGCATC TAAGACTCCA GCCTCGATAT TTGGCCCTTC AGCTGCCAGC





64501
CATCTCCTGA TACTATTCAC CCTCAACTTC ACCATCACTA ACCTGCGGTA





64551
TGAGGAGAAC ATGTGGCCTG GCTCCAGGAA GTTCAACACT ACAGAGAGGG





64601
TCCTTCAGGG CCTGCTAAGG CCCTTGTTCA AGAACACCAG TGTTGGCCCT





64651
CTGTACTCTG GCTCCAGGCT GACCTTGCTC AGGCCAGAGA AAGATGGGGA





64701
AGCCACCGGA GTGGATGCCA TCTGCACCCA CCGCCCTGAC CCCACAGGCC





64751
CTGGGCTGGA CAGAGAGCAG CTGTATTTGG AGCTGAGCCA GCTGACCCAC





64801
AGCATCACTG AGCTGGGCCC CTACACACTG GACAGGGACA GTCTCTATGT





64851
CAATGGTTTC ACCCATCGGA GCTCTGTACC CACCACCAGC ACCGGGGTGG





64901
TCAGCGAGGA GCCATTCACA CTGAACTTCA CCATCAACAA CCTGCGCTAC





64951
ATGGCGGACA TGGGCCAACC CGGCTCCCTC AAGTTCAACA TCACAGACAA





65001
CGTCATGAAG CACCTGCTCA GTCCTTTGTT CCAGAGGAGC AGCCTGGGTG





65051
CACGGTACAC AGGCTGCAGG GTCATCGCAC TAAGGTCTGT GAAGAACGGT





65101
GCTGAGACAC GGGTGGACCT CCTCTGCACC TACCTGCAGC CCCTCAGCGG





65151
CCCAGGTCTG CCTATCAAGC AGGTGTTCCA TGAGCTGAGC CAGCAGACCC





65201
ATGGCATCAC CCGGCTGGGC CCCTACTCTC TGGACAAAGA CAGCCTCTAC





65251
CTTAACGGTT ACAATGAACC TGGTCTAGAT GAGCCTCCTA CAACTCCCAA





65301
GCCAGCCACC ACATTCCTGC CTCCTCTGTC AGAAGCCACA ACAGCCATGG





65351
GGTACCACCT GAAGACCCTC ACACTCAACT TCACCATCTC CAATCTCCAG





65401
TATTCACCAG ATATGGGCAA GGGCTCAGCT ACATTCAACT CCACCGAGGG





65451
GGTCCTTCAG CACCTGCTCA GACCCTTGTT CCAGAAGAGC AGCATGGGCC





65501
CCTTCTACTT GGGTTGCCAA CTGATCTCCC TCAGGCCTGA GAAGGATGGG





65551
GCAGCCACTG GTGTGGACAC CACCTGCACC TACCACCCTG ACCCTGTGGG





65601
CCCCGGGCTG GACATACAGC AGCTTTACTG GGAGCTGAGT CAGCTGACCC





65651
ATGGTGTCAC CCAACTGGGC TTCTATGTCC TGGACAGGGA TAGCCTCTTC





65701
ATCAATGGCT ATGCACCCCA GAATTTATCA ATCCGGGGCG AGTACCAGAT





65751
AAATTTCCAC ATTGTCAACT GGAACCTCAG TAATCCAGAC CCCACATCCT





65801
CAGAGTACAT CACCCTGCTG AGGGACATCC AGGACAAGGT CACCACACTC





65851
TACAAAGGCA GTCAACTACA TGACACATTC CGCTTCTGCC TGGTCACCAA





65901
CTTGACGATG GACTCCGTGT TGGTCACTGT CAAGGCATTG TTCTCCTCCA





65951
ATTTGGACCC CAGCCTGGTG GAGCAAGTCT TTCTAGATAA GACCCTGAAT





66001
GCCTCATTCC ATTGGCTGGG CTCCACCTAC CAGTTGGTGG ACATCCATGT





66051
GACAGAAATG GAGTCATCAG TTTATCAACC AACAAGCAGC TCCAGCACCC





66101
AGCACTTCTA CCTGAATTTC ACCATCACCA ACCTACCATA TTCCCAGGAC





66151
AAAGCCCAGC CAGGCACCAC CAATTACCAG AGGAACAAAA GGAATATTGA





66201
GGATGCGCTC AACCAACTCT TCCGAAACAG CAGCATCAAG AGTTATTTTT





66251
CTGACTGTCA AGTTTCAACA TTCAGGTCTG TCCCCAACAG GCACCACACC





66301
GGGGTGGACT CCCTGTGTAA CTTCTCGCCA CTGGCTCGGA GAGTAGACAG





66351
AGTTGCCATC TATGAGGAAT TTCTGCGGAT GACCCGGAAT GGTACCCAGC





66401
TGCAGAACTT CACCCTGGAC AGGAGCAGTG TCCTTGTGGA TGGGTATTCT





66451
CCCAACAGAA ATGAGCCCTT AACTGGGAAT TCTGACCTTC CCTTCTGGGC





66501
TGTCATCCTC ATCGGCTTGG CAGGACTCCT GGGACTCATC ACATGCCTGA





66551
TCTGCGGTGT CCTGGTGACC ACCCGCCGGC GGAAGAAGGA AGGAGAATAC





66601
AACGTCCAGC AACAGTGCCC AGGCTACTAC CAGTCACACC TAGACCTGGA





66651
GGATCTGCAA TGACTGGAAC TTGCCGGTGC CTGGGGTGCC TTTCCCCCAG





66701
CCAGGGTCCA AAGAAGCTTG GCTGGGGCAG AAATAAACCA TATTGGTCGG





66751
AAAAAAAAAA AAAAA
















TABLE 5





Human Protein of CA125 Molecule


(SEQ ID NO: 5)
















1
MLKPSGLPGS SSPTRSLMTG SRSTKATPEM DSGLTGATLS PKTSTGAIVV





51
TEHTLPFTSP DKTLASPTSS VVGRTTQSLG VMSSALPEST SRGMTHSEQR





101
TSPSLSPQVN GTPSRNYPAT SMVSGLSSPR TRTSSTEGNF TKEASTYTLT





151
VETTSGPVTE KYTVPTETST TEGDSTETPW DTRYIPVKIT SPMKTFADST





201
ASKENAPVSM TPAETTVTDS HTPGRTNPSF GTLYSSFLDL SPKGTPNSRG





251
ETSLELILST TGYPFSSPEP GSAGHSRIST SAPLSSSASV LDNKISETSI





301
FSGQSLTSPL SPGVPEARAS TMPNSAIPFS MTLSNAETSA ERVRSTISSL





351
GTPSISTKQT AETILTFHAF AETMDIPSTH IAKTLASEWL GSPGTLGGTS





401
TSALTTTSPS TTLVSEETNT HHSTSGKETE GTLNTSMTPL ETSAPGEESE





451
MTATLVPTLG FTTLDSKIRS PSQVSSSHPT RELRTTGSTS GRQSSSTAAH





501
GSSDILRATT SSTSKASSWT SESTAQQFSE PQHTQWVETS PSMKTERPPA





551
STSVAAPITT SVPSVVSGFT TLKTSSTKGI WLEETSADTL IGESTAGPTT





601
HQFAVPTGIS MTGGSSTRGS QGTTHLLTRA TASSETSADL TLATNGVPVS





651
VSPAVSKTAA GSSPPGGTKP SYTMVSSVIP ETSSLQSSAF REGTSLGLTP





701
LNTRHPFSSP EPDSAGHTKI STSIPLLSSA SVLEDKVSAT STFSHHKATS





751
SITTGTPEIS TKTKPSSAVL SSMTLSNAAT SPERVRNATS PLTHPSPSGE





801
ETAGSVLTLS TSAETTDSPN IHPTGTLTSE SSESPSTLSL PSVSGVKTTF





851
SSSTPSTHLF TSGEETEETS NPSVSQPETS VSRVRTTLAS TSVPTPVFPT





901
MDTWPTRSAQ FSSSHLVSEL RATSSTSVTN STGSALPKIS HLTGTATMSQ





951
TNRDTFNDSA APQSTTWPET SPRFKTGLPS ATTTVSTSAT SLSATVMVSK





1001
FTSPATSSME ATSIREPSTT ILTTETTNGP GSMAVASTNI PIGKGYITEG





1051
RLDTSHLPIG TTASSETSMD FTMAKESVSM SVSPSQSMDA AGSSTPGRTS





1101
QFVDTFSDDV YHLTSREITI PRDGTSSALT PQMTATHPPS PDPGSARSTW





1151
LGILSSSPSS PTPKVTMSST FSTQRVTTSM IMDTVETSRW NMPNLPSTTS





1201
LTPSNIPTSG AIGKSTLVPL DTPSPATSLE ASEGGLPTLS TYPESTNTPS





1251
IHLGAHASSE SPSTINLTMA SVVKPGSYTP LTFPSIETHI HVSTARMAYS





1301
SGSSPEMTAP GETNTGSTWD PTTYITTTDP KDTSSAQVST PHSVRTLRTT





1351
ENHPKTESAT PAAYSGSPKI SSSPNLTSPA TKAWTITDTT EHSTQLHYTK





1401
LAEKSSGFET QSAPGPVSVV IPTSPTIGSS TLELTSDVPG EPLVLAPSEQ





1451
TTITLPMATW LSTSLTEEMA STDLDISSPS SPMSTFAIFP PMSTPSHELS





1501
KSEADTSAIR NTDSTTLDQH LGIRSLGRTG DLTTVPITPL TTTWTSVIEH





1551
STQAQDTLSA TMSPTHVTQS LKDQTSIPAS ASPSHLTEVY PELGTQGRSS





1601
SEATTFWKPS TDTLSREIET GPTNIQSTPP MDNTTTGSSS SGVTLGIAHL





1651
PIGTSSPAET STNMALERRS STATVSMAGT MGLLVTSAPG RSISQSLGRV





1701
SSVLSESTTE GVTDSSKGSS PRLNTQGNTA LSSSLEPSYA EGSQMSTSIP





1751
LTSSPTTPDV EFIGGSTFWT KEVTTVMTSD ISKSSARTES SSATLMSTAL





1801
GSTENTGKEK LRTASMDLPS PTPSMEVTPW ISLTLSNAPN TTDSLDLSHG





1851
VHTSSAGTLA TDRSLNTGVT RASRLENGSD TSSKSLSMGN STHTSMTDTE





1901
KSEVSSSIHP RPETSAPGAE TTLTSTPGNR AISLTLPFSS IPVEEVISTG





1951
ITSGPDINSA PMTHSPITPP TIVWTSTGTI EQSTQPLHAV SSEKVSVQTQ





2001
STPYVNSVAV SASPTHENSV SSGSSTSSPY SSASLESLDS TISRRNAITS





2051
WLWDLTTSLP TTTWPSTSLS EALSSGHSGV SNPSSTTTEF PLFSAASTSA





2101
AKQRNPETET HGPQNTAAST LNTDASSVTG LSETPVGASI SSEVPLPMAI





2151
TSRSDVSGLT SESTANPSLG TASSAGTKLT RTISLPTSES LVSFRMNKDP





2201
WTVSIPLGSH PTTNTETSIP VNSAGPPGLS TVASDVIDTP SDGAESIPTV





2251
SFSPSPDTEV TTISHFPEKT THSFRTISSL THELTSRVTP IPGDWMSSAM





2301
STKPTGASPS ITLGERRTIT SAAPTTSPIV LTASFTETST VSLDNETTVK





2351
TSDILDARKT NELPSDSSSS SDLINTSIAS STMDVTKTAS ISPTSISGMT





2401
ASSSPSLFSS DRPQVPTSTT ETNTATSPSV SSNTYSLDGG SNVGGTPSTL





2451
PPFTITHPVE TSSALLAWSR PVRTFSTMVS TDTASGENPT SSNSVVTSVP





2501
APGTWASVGS TTDLPAMGFL KTSPAGEAHS LLASTIEPAT AFTPHLSAAV





2551
VTGSSATSEA SLLTTSESKA IHSSPQTPTT PTSGANWETS ATPESLLVVT





2601
ETSDTTLTSK ILVTDTILFS TVSTPPSKFP STGTLSGASF PTLLPDTPAI





2651
PLTATEPTSS LATSFDSTPL VTIASDSLGT VPETTLTMSE TSNGDALVLK





2701
TVSNPDRSIP GITIQGVTES PLHPSSTSPS KIVAPRNTTY EGSITVALST





2751
LPAGTTGSLV FSQSSENSET TALVDSSAGL ERASVMPLTT GSQGMASSGG





2801
IRSGSTHSTG TKTFSSLPLT MNPGEVTAMS EITTNRLTAT QSTAPKGIPV





2851
KPTSAESGLL TPVSASSSPS KAFASLTTAP PSTWGIPQST LTFEFSEVPS





2901
LDTKSASLPT PGQSLNTIPD SDASTASSSL SKSPEKNPRA RMMTSTKAIS





2951
ASSFQSTGFT ETPEGSASPS MAGHEPRVPT SGTGDPRYAS ESMSYPDPSK





3001
ASSAMTSTSL ASKLTTLFST GQAARSGSSS SPISLSTEKE TSFLSPTAST





3051
SRKTSLFLGP SMARQPNILV HLQTSALTLS PTSTLNMSQE EPPELTSSQT





3101
IAEEEGTTAE TQTLTFTPSE TPTSLLPVSS PTEPTARRKS SPETWASSIS





3151
VPAKTSLVET TDGTLVTTIK MSSQAAQGNS TWPAPAEETG TSPAGTSPGS





3201
PEVSTTLKIM SSKEPSISPE IRSTVRNSPW KTPETTVPME TTVEPVTLQS





3251
TALGSGSTSI SHLPTGTTSP TKSPTENMLA TERVSLSPSP PEAWTNLYSG





3301
TPGGTRQSLA TMSSVSLESP TARSITGTGQ QSSPELVSKT TGMEFSMWHG





3351
STGGTTGDTH VSLSTSSNIL EDPVTSPNSV SSLTDKSKHK TETWVSTTAI





3401
PSTVLNNKIM AAEQQTSRSV DEAYSSTSSW SDQTSGSDIT LGASPDVTNT





3451
LYITSTAQTT SLVSLPSGDQ GITSLTNPSG GKTSSASSVT SPSIGLETLR





3501
ANVSAVKSDI APTAGHLSQT SSPAEVSILD VTTAPTPGIS TTITTMGTNS





3551
ISTTTPNPEV GMSTMDSTPA TERRTTSTEH PSTWSSTAAS DSWTVTDMTS





3601
NLKVARSPGT ISTMHTTSFL ASSTELDSMS TPHGRITVIG TSLVTPSSDA





3651
SAVKTETSTS ERTLSPSDTT ASTPISTFSR VQRMSISVPD ILSTSWTPSS





3701
TEAEDVPVSM VPTDHASTKT DPNTPLSTFL FDSLSTLDWD TGRSLSSATA





3751
TTSAPQGATT PQELTLETMI SPATSQLPFS IGHITSAVTP AAMARSSGVT





3801
FSRPDPTSKK AEQTSTQLPT TTSAHPGQVP RSAATTLDVI PHTAKTPDAT





3851
FQRQGQTALT TEARATSDSW NEKEKSTPSA PWITEMMNSV SEDTIKEVTS





3901
SSSVLKDPEY AGHKLGIWDD FIPKFGKAAH MRELPLLSPP QDKEAIHPST





3951
NTVETTGWVT SSEHASHSTI PAHSASSKLT SPVVTTSTRE QAIVSMSTTT





4001
WPESTRARTE PNSFLTIELR DVSPYMDTSS TTQTSIISSP GSTAITKGHR





4051
TEITSYKRIS SSFLAQSMRS SDSPSEAITR LSNFPAMTES GGMILAMQTS





4101
PPGATSISAP TLDTSATASW TGTPLATTQR FTYSEKTTLF SKGREDTSQP





4151
SPPCVEETSS SSSVVPIHAT TSPSNILLTS QGHSPSSTPP VTSVFLSETS





4201
GLGKTTDMSR ISLEPGTSLP PNLSSTAGEA LSTYEASRDT KAIHHSADTA





4251
VTNMEATSSE YSPIPGHTKP SKATSPLVTS HIMGDITSST SVFGSSETTE





4301
IETVSSVNQG LQERSTSQVA SSATETSTVI THVSSGDATT HVTKTQATFS





4351
SGTSISSPHQ FITSTNTFTD VSTNPSTSLI MTESSGVTIT TQTGPTGAAT





4401
QGPYLLDTST MPYLTETPLA VTPDFMQSEK TTLISKGPKD VTWTSPPSVA





4451
ETSYPSSLTP FLVTTIPPAT STLQGQHTSS PVSATSVLTS GLVKTTDMLN





4501
TSMEPVTNSP QNLNNPSNEI LATLAATTDI ETIHPSINKA VTNMGTASSA





4551
HVLHSTLPVS SEPSTATSPM VPASSMGDAL ASISIPGSET TDIEGEPTSS





4601
LTAGRKENST LQEMNSTTES NIILSNVSVG AITEATKMEV PSFDATFIPT





4651
PAQSTKFPDI FSVASSRLSN SPPMTISTHM TTTQTGSSGA TSKIPLALDT





4701
STLETSAGTP SVVTEGFAHS KITTAMNNDV KDVSQTNPPF QDEASSPSSQ





4751
APVLVTTLPS SVAFTPQWHS TSSPVSMSSV LTSSLVKTAG KVDTSLETVT





4801
SSPQSMSNTL DDISVTSAAT TDIETTHPSI NTVVTNVGTT GSAFESHSTV





4851
SAYPEPSKVT SPNVTTSTME DTTISRSIPK SSKTTRTETE TTSSLTPKLR





4901
ETSISQEITS STETSTVPYK ELTGATTEVS RTDVTSSSST SFPGPDQSTV





4951
SLDISTETNT RLSTSPIMTE SAEITITTQT GPHGATSQDT FTMDPSNTTP





5001
QAGIHSAMTH GFSQLDVTTL MSRIPQDVSW TSPPSVDKTS SPSSFLSSPA





5051
MTTPSLISST LPEDKLSSPM TSLLTSGLVK ITDILRTRLE PVTSSLPNFS





5101
STSDKILATS KDSKDTKEIF PSINTEETNV KANNSGHESH SPALADSETP





5151
KATTQMVITT TVGDPAPSTS MPVHGSSETT NIKREPTYFL TPRLRETSTS





5201
QESSFPTDTS FLLSKVPTGT ITEVSSTGVI SSSKISTPDH DKSTVPPDTF





5251
TGEIPRVFTS SIKTKSAEMT ITTQASPPES ASHSTLPLDT STTLSQGGTH





5301
STVSQGFPYS EVTTLMGMGP GNVSWMTTPP VEETSSVSSL MSSPAMTSPS





5351
PVSSTSPQSI PSSPLPVTAL PTSVLVTTTD VLGTTSPESV TSSPPNLSSI





5401
THERPATYKD TAHTEAAMHH STNTAVTNVG TSGSGHKSQS SVLADSETSK





5451
ATPLMSTAST LGDTSVSTST PNISQTNQIQ TEPTASLSPR LRESSTSEKT





5501
SSTTETNTAF SYVPTGAITQ ASRTEISSSR TSISDLDRST IAPDISTGMI





5551
TRLFTSPIMT KSAEMTVTTQ TTTPGATSQG ILPWDTSTTL FQGGTHSTVS





5601
QGFPHSEITT LRSRTPGDVS WMTTPPVEET SSGFSLMSPS MTSPSPVSST





5651
SPESIPSSPL PVTALLTSVL VTTTNVLGTT SPEPVTSSPP NLSSPTQERL





5701
TTYKDTAHTE AMHASMHTNT AVANVGTSIS GHESQSSVPA DSHTSKATSP





5751
MGITFAMGDT SVYTSTPAFF ETRIQSESTS SLIPGLRDTR TSEEINTVTE





5801
TSTVLSEVPT TTTTEVSRTE VITSSRTTIS GPDHSKMSPY ISTETITRLS





5851
TFPFVTGSTE MAITNQTGPI GTISQATLTL DTSSTASWEG THSPVTQRFP





5901
HSEETTTMSR STKGVSWQSP PSVEETSSPS SPVPLPAITS HSSLYSAVSG





5951
SSPTSALPVT SLLTSGRRKT IDMLDTHSEL VTSSLPSASS FSGEILTSEA





6001
STNTETIHFS ENTAETNMGT TNSMHKLHSS VSIHSQPSGH TPPKVTGSMM





6051
EDAIVSTSTP GSPETKNVDR DSTSPLTPEL KEDSTALVMN STTESNTVFS





6101
SVSLDAATEV SRAEVTYYDP TFMPASAQST KSPDISPEAS SSHSNSPPLT





6151
ISTHKTIATQ TGPSGVTSLG QLTLDTSTIA TSAGTPSART QDFVDSETTS





6201
VMNNDLNDVL KTSPFSAEEA NSLSSQAPLL VTTSPSPVTS TLQEHSTSSL





6251
VSVTSVPTPT LAKITDMDTN LEPVTRSPQN LRNTLATSEA TTDTHTMHPS





6301
INTAMANVGT TSSPNEFYFT VSPDSDPYKA TSAVVITSTS GDSIVSTSMP





6351
RSSAMKKIES ETTFSLIFRL RETSTSQKIG SSSDTSTVFD KAFTAATTEV





6401
SRTELTSSSR TSIQGTEKPT MSPDTSTRSV TMLSTFAGLT KSEERTIATQ





6451
TGPHRATSQG TLTWDTSITT SQAGTHSAMT HGFSQLDLST LTSRVPEYIS





6501
GTSPPSVEKT SSSSSLLSLP AITSPSPVPT TLPESRPSSP VHLTSLPTSG





6551
LVKTTDMLAS VASLPPNLGS TSHKIPTTSE DIKDTEKMYP STNIAVTNVG





6601
TTTSEKESYS SVPAYSEPPK VTSPMVTSFN IRDTIVSTSM PGSSEITRIE





6651
MESTFSLAHG LKGTSTSQDP IVSTEKSAVL HKLTTGATET SRTEVASSRR





6701
TSIPGPDHST ESPDISTEVI PSLPISLGIT ESSNMTIITR TGPPLGSTSQ





6751
GTFTLDTPTT SSRAGTHSMA TQEFPHSEMT TVMNKDPEIL SWTIPPSIEK





6801
TSFSSSLMPS PAMTSPPVSS TLPKTIHTTP SPMTSLLTPS LVMTTDTLGT





6851
SPEPTTSSPP NLSSTSHVIL TTDEDTTAIE AMHPSTSTAA TNVETTCSGH





6901
GSQSSVLTDS EKTKATAPMD TTSTMGHTTV STSMSVSSET TKIKRESTYS





6951
LTPGLRETSI SQNASFSTDT SIVLSEVPTG TTAEVSRTEV TSSGRTSIPG





7001
PSQSTVLPEI STRTMTRLFA SPTMTESAEM TIPTQTGPSG STSQDTLTLD





7051
TSTTKSQAKT HSTLTQRFPH SEMTTLMSRG PGDMSWQSSP SLENPSSLPS





7101
LLSLPATTSP PPISSTLPVT ISSSPLPVTS LLTSSPVTTT DMLHTSPELV





7151
TSSPPKLSHT SDERLTTGKD TTNTEAVHPS TNTAASNVEI PSFGHESPSS





7201
ALADSETSKA TSPMFITSTQ EDTTVAISTP HFLETSRIQK ESISSLSPKL





7251
RETGSSVETS SAIETSAVLS EVSIGATTEI SRTEVTSSSR TSISGSAEST





7301
MLPEISTTRK IIKFPTSPIL AESSEMTIKT QTSPPGSTSE STFTLDTSTT





7351
PSLVITHSTM TQRLPHSEIT TLVSRGAGDV PRPSSLPVEE TSPPSSQLSL





7401
SAMISPSPVS STLPASSHSS SASVTSPLTP GQVKTTEVLD ASAEPETSSP





7451
PSLSSTSVEI LATSEVTTDT EKIHPFPNTA VTKVGTSSSG HESPSSVLPD





7501
SETTKATSAM GTISIMGDTS VSTLTPALSN TRKIQSEPAS SLTTRLRETS





7551
TSEETSLATE ANTVLSKVST GATTEVSRTE AISFSRTSMS GPEQSTMSQD





7601
ISIGTIPRIS ASSVLTESAK MTITTQTGPS ESTLESTLNL NTATTPSWVE





7651
THSIVIQGFP HPEMTTSMGR GPGGVSWPSP PFVKETSPPS SPLSLPAVTS





7701
PHPVSTTFLA HIPPSPLPVT SLLTSGPATT TDILGTSTEP GTSSSSSLST





7751
TSHERLTTYK DTAHTEAVHP STNTGGTNVA TTSSGYKSQS SVLADSSPMC





7801
TTSTMGDTSV LTSTPAFLET RRIQTELASS LTPGLRESSG SEGTSSGTKM





7851
STVLSKVPTG ATTEISKEDV TSIPGPAQST ISPDTSTRTV SWFSTSPVMT





7901
ESAEITMNTH TSPLGATTQG TSTLDTSSTT SLTMTHSTIS QGFSHSQMST





7951
LMRRGPEDVS WMSPPLLEKT RPSFSLMSSP ATTSPSPVSS TLPESISSSP





8001
LPVTSLLTSG LAKTTDMLHK SSEPVTNSPA NLSSTSVEIL ATSEVTTDTE





8051
KTHPSSNRTV TDVGTSSSGH ESTSFVLADS QTSKVTSPMV ITSTMEDTSV





8101
STSTPGFFET SRIQTEPTSS LTLGLRKTSS SEGTSLATEM STVLSGVPTG





8151
ATAEVSRTEV TSSSRTSISG FAQLTVSPET STETITRLPT SSIMTESAEM





8201
MIKTQTDPPG STPESTHTVD ISTTPNWVET HSTVTQRFSH SEMTTLVSRS





8251
PGDMLWPSQS SVEETSSASS LLSLPATTSP SPVSSTLVED FPSASLPVTS





8301
LLTPGLVITT DRMGISREPG TSSTSNLSST SHERLTTLED TVDTEAMQPS





8351
THTAVTNVRT SISGHESQSS VLSDSETPKA TSSMGTTYTM GETSVSISTS





8401
DFFETSRVQI EPTSSLTSGL RETSSSERIS SATEGSTVLS EVPSGATTEV





8451
SRTEVISSRG TSMSGPDQFT ISPDISTEAI TRLSTSPIMT ESAESAITIE





8501
TGSPGATSEG TLTLDTSTTT FWSGTHSTAS PGFSHSEMTT LMSRTPGDVP





8551
WPSLPSVEEA SSVSSSLSSP AMTSTSFFSA LPESISSSPH PVTALLTLGP





8601
VKTTDMLRTS SEPETSSPPN LSSTSAEILA TSEVTKDREK IHPSSNTPVV





8651
NVGTVIYKHL SPSSVLADLV TTKPTSPMAT TSTLGNTSVS TSTPAFPETM





8701
MTQPTSSLTS GLREISTSQE TSSATERSAS LSGMPTGATT KVSRTEALSL





8751
GRTSTPGPAQ STISPEISTE TITRISTPLT TTGSAEMTIT PKTGHSGASS





8801
QGTFTLDTSS RASWPGTHSA ATHRSPHSGM TTPMSRGPED VSWPSRPSVE





8851
KTSPPSSLVS LSAVTSPSPL YSTPSESSHS SPLRVTSLFT PVMMKTTDML





8901
DTSLEPVTTS PPSMNITSDE SLATSKATME TEAIQLSENT AVTQMGTISA





8951
RQEFYSSYPG LPEPSKVTSP VVTSSTIKDI VSTTIPASSE ITRIEMESTS





9001
TLTPTPRETS TSQEIHSATK PSTVPYKALT SATIEDSMTQ VMSSSRGPSP





9051
DQSTMSQDIS TEVITRLSTS PIKAESTEMT ITTQTGSPGA TSRGTLTLDT





9101
STTFMSGTHS TASQGFSHSQ MTALMSRTPG DVPWLSHPSV EEASSASFSL





9151
SSPVMTSSSP VSSTLPDSIH SSSLPVTSLL TSGLVKTTEL LGTSSEPETS





9201
SPPNLSSTSA EILATTEVTT DTEKLEMTNV VTSGYTHESP SSVLADSVTT





9251
KATSSMGITY PTGDTNVLTS TPAFSDTSRI QTKSKLSLTP GLMETSISEE





9301
TSSATEKSTV LSSVPTGATT EVSRTEAISS SRTSIPGPAQ STMSSDTSME





9351
TITRISTPLT RKESTDMAIT PKTGPSGATS QGTFTLDSSS TASWPGTHSA





9401
TTQRFPQSVV TTPMSRGPED VSWPSPLSVE KNSPPSSLVS SSSVTSPSPL





9451
YSTPSGSSHS SPVPVTSLFT SIMMKATDML DASLEPETTS APNMNITSDE





9501
SLATSKATTE TEAIHVFENT AASHVETTSA TEELYSSSPG FSEPTKVISP





9551
VVTSSSIRDN MVSTTMPGSS GITRIEIESM SSLTPGLRET RTSQDITSST





9601
ETSTVLYKMS SGATPEVSRT EVMPSSRTSI PGPAQSTMSL DISDEVVTRL





9651
STSPIMTESA EITITTQTGY SLATSQVTLP LGTSMTFLSG THSTMSQGLS





9701
HSEMTNLMSR GPESLSWTSP RFVETTRSSS SLTSLPLTTS LSPVSSTLLD





9751
SSPSSPLPVT SLILPGLVKT TEVLDTSSEP KTSSSPNLSS TSVEIPATSE





9801
IMTDTEKIHP SSNTAVAKVR TSSSVHESHS SVLADSETTI TIPSMGITSA





9851
VDDTTVFTSN PAFSETRRIP TEPTFSLTPG FRETSTSEET TSITETSAVL





9901
YGVPTSATTE VSMTEIMSSN RTHIPDSDQS TMSPDIITEV ITRLSSSSMM





9951
SESTQMTITT QKSSPGATAQ STLTLATTTA PLARTHSTVP PRFLHSEMTT





10001
LMSRSPENPS WKSSPFVEKT SSSSSLLSLP VTTSPSVSST LPQSIPSSSF





10051
SVTSLLTPGM VKTTDTSTEP GTSLSPNLSG TSVEILAASE VTTDTEKIHP





10101
SSSMAVTNVG TTSSGHELYS SVSIHSEPSK ATYPVGTPSS MAETSISTSM





10151
PANFETTGFE AEPFSHLTSG FRKTNMSLDT SSVTPTNTPS SPGSTHLLQS





10201
SKTDFTSSAK TSSPDWPPAS QYTEIPVDII TPFNASPSIT ESTGITSFPE





10251
SRFTMSVTES THHLSTDLLP SAETISTGTV MPSLSEAMTS FATTGVPRAI





10301
SGSGSPFSRT ESGPGDATLS TIAESLPSST PVPFSSSTFT TTDSSTIPAL





10351
HEITSSSATP YRVDTSLGTE SSTTEGRLVM VSTLDTSSQP GRTSSTPILD





10401
TRMTESVELG TVTSAYQVPS LSTRLTRTDG IMEHITKIPN EAAHRGTIRP





10451
VKGPQTSTSP ASPKGLHTGG TKRMETTTTA LKTTTTALKT TSRATLTTSV





10501
YTPTLGTLTP LNASRQMAST ILTEMMITTP YVFPDVPETT SSLATSLGAE





10551
TSTALPRTTP SVLNRESETT ASLVSRSGAE RSPVIQTLDV SSSEPDTTAS





10601
WVIHPAETIP TVSKTTPNFF HSELDTVSST ATSHGADVSS AIPTNISPSE





10651
LDALTPLVTI SGTDTSTTFP TLTKSPHETE TRTTWLTHPA ETSSTIPRTI





10701
PNFSHHESDA TPSIATSPGA ETSSAIPIMT VSPGAEDLVT SQVTSSGTDR





10751
NMTIPTLTLS PGEPKTIASL VTHPEAQTSS AIPTSTISPA VSRLVTSMVT





10801
SLAAKTSTTN RALTNSPGEP ATTVSLVTHP AQTSPTVPWT TSIFFHSKSD





10851
TTPSMTTSHG AESSSAVPTP TVSTEVPGVV TPLVTSSRAV ISTTIPILTL





10901
SPGEPETTPS MATSHGEEAS SAIPTPTVSP GVPGVVTSLV TSSRAVTSTT





10951
IPILTFSLGE PETTPSMATS HGTEAGSAVP TVLPEVPGMV TSLVASSRAV





11001
TSTTLPTLTL SPGEPETTPS MATSHGAEAS STVPTVSPEV PGVVTSLVTS





11051
SSGVNSTSIP TLILSPGELE TTPSMATSHG AEASSAVPTP TVSPGVSGVV





11101
TPLVTSSRAV TSTTIPILTL SSSEPETTPS MATSHGVEAS SAVLTVSPEV





11151
PGMVTSLVTS SRAVTSTTIP TLTISSDEPE TTTSLVTHSE AKMISAIPTL





11201
AVSPTVQGLV TSLVTSSGSE TSAFSNLTVA SSQPETIDSW VAHPGTEASS





11251
VVPTLTVSTG EPFTNISLVT HPAESSSTLP RTTSRFSHSE LDTMPSTVTS





11301
PEAESSSAIS TTISPGIPGV LTSLVTSSGR DISATFPTVP ESPHESEATA





11351
SWVTHPAVTS TTVPRTTPNY SHSEPDTTPS IATSPGAEAT SDFPTITVSP





11401
DVPDMVTSQV TSSGTDTSIT IPTLTLSSGE PETTTSFITY SETHTSSAIP





11451
TLPVSPGASK MLTSLVISSG TDSTTTFPTL TETPYEPETT AIQLIHPAET





11501
NTMVPRTTPK FSHSKSDTTL PVAITSPGPE ASSAVSTTTI SPDMSDLVTS





11551
LVPSSGTDTS TTFPTLSETP YEPETTATWL THPAETSTTV SGTIPNFSHR





11601
GSDTAPSMVT SPGVDTRSGV PTTTIPPSIP GVVTSQVTSS ATDTSTAIPT





11651
LTPSPGEPET TASSATHPGT QTGFTVPIRT VPSSEPDTMA SWVTHPPQTS





11701
TPVSRTTSSF SHSSPDATPV MATSPRTEAS SAVLTTISPG APEMVTSQIT





11751
SSGAATSTTV PTLTHSPGMP ETTALLSTHP RTETSKTFPA STVFPQVSET





11801
TASLTIRPGA ETSTALPTQT TSSLFTLLVT GTSRVDLSPT ASPGVSAKTA





11851
PLSTHPGTET STMIPTSTLS LGLLETTGLL ATSSSAETST STLTLTVSPA





11901
VSGLSSASIT TDKPQTVTSW NTETSPSVTS VGPPEFSRTV TGTTMTLIPS





11951
EMPTPPKTSH GEGVSPTTIL RTTMVEATNL ATTGSSPTVA KTTTTFNTLA





12001
GSLFTPLTTP GMSTLASESV TSRTSYNHRS WISTTSSYNR RYWTPATSTP





12051
VTSTFSPGIS TSSIPSSTAA TVPFMVPFTL NFTITNLQYE EDMRHPGSRK





12101
FNATERELQG LLKPLFRNSS LEYLYSGCRL ASLRPEKDSS AMAVDAICTH





12151
RPDPEDLGLD RERLYWELSN LTNGIQELGP YTLDRNSLYV NGFTHRSSMP





12201
TTSTPGTSTV DVGTSGTPSS SPSPTAAGPL LMPFTLNFTI TNLQYEEDMR





12251
RTGSRKFNTM ESVLQGLLKP LFKNTSVGPL YSGCRLTLLR PEKDGAATGV





12301
DAICTHRLDP KSPGLNREQL YWELSKLTND IEELGPYTLD RNSLYVNGFT





12351
HQSSVSTTST PGTSTVDLRT SGTPSSLSSP TIMAAGPLLV PFTLNFTITN





12401
LQYGEDMGHP GSRKFNTTER VLQGLLGPIF KNTSVGPLYS GCRLTSLRSE





12451
KDGAATGVDA ICIHHLDPKS PGLNRERLYW ELSQLTNGIK ELGPYTLDRN





12501
SLYVNGFTHR TSVPTSSTPG TSTVDLGTSG TPFSLPSPAT AGPLLVLFTL





12551
NFTITNLKYE EDMHRPGSRK FNTTERVLQT LLGPMFKNTS VGLLYSGCRL





12601
TLLRSEKDGA ATGVDAICTH RLDPKSPGLD REQLYWELSQ LTNGIKELGP





12651
YTLDRNSLYV NGFTHWIPVP TSSTPGTSTV DLGSGTPSSL PSPTAAGPLL





12701
VPFTLNFTIT NLQYEEDMHH PGSRKFNTTE RVLQGLLGPM FKNTSVGLLY





12751
SGCRLTLLRS EKDGAATGVD AICTHRLDPK SPGVDREQLY WELSQLTNGI





12801
KELGPYTLDR NSLYVNGFTH QTSAPNTSTP GTSTVDLGTS GTPSSLPSPT





12851
SAGPLLVPFT LNFTITNLQY EEDMRHPGSR KFNTTERVLQ GLLKPLFKST





12901
SVGPLYSGCR LTLLRSEKDG AATGVDAICT HRLDPKSPGV DREQLYWELS





12951
QLTNGIKELG PYTLDRNSLY VNGFTHQTSA PNTSTPGTST VDLGTSGTPS





13001
SLPSPTSAGP LLVPFTLNFT ITNLQYEEDM HHPGSRKFNT TERVLQGLLG





13051
PMFKNTSVGL LYSGCRLTLL RPEKNGAATG MDAICSHRLD PKSPGLNREQ





13101
LYWELSQLTH GIKELGPYTL DRNSLYVNGF THRSSVAPTS TPGTSTVDLG





13151
TSGTPSSLPS PTTAVPLLVP FTLNFTITNL QYGEDMRHPG SRKFNTTERV





13201
LQGLLGPLFK NSSVGPLYSG CRLISLRSEK DGAATGVDAI CTHHLNPQSP





13251
GLDREQLYWQ LSQMTNGIKE LGPYTLDRNS LYVNGFTHRS SGLTTSTPWT





13301
STVDLGTSGT PSPVPSPTTA GPLLVPFTLN FTITNLQYEE DMHRPGSRKF





13351
NATERVLQGL LSPIFKNSSV GPLYSGCRLT SLRPEKDGAA TGMDAVCLYH





13401
PNPKRPGLDR EQLYWELSQL THNITELGPY SLDRDSLYVN GFTHQNSVPT





13451
TSTPGTSTVY WATTGTPSSF PGHTEPGPLL IPFTFNFTIT NLHYEENMQH





13501
PGSRKFNTTE RVLQGLLKPL FKNTSVGPLY SGCRLTSLRP EKDGAATGMD





13551
AVCLYHPNPK RPGLDREQLY CELSQLTHNI TELGPYSLDR DSLYVNGFTH





13601
QNSVPTTSTP GTSTVYWATT GTPSSFPGHT EPGPLLIPFT FNFTITNLHY





13651
EENMQHPGSR KFNTTERVLQ GLLKPLFKNT SVGPLYSGCR LTLLRPEKHE





13701
AATGVDTICT HRVDPIGPGL DRERLYWELS QLTNSITELG PYTLDRDSLY





13751
VNGFNPRSSV PTTSTPGTST VHLATSGTPS SLPGHTAPVP LLIPFTLNFT





13801
ITNLHYEENM QHPGSRKFNT TERVLQGLLK PLFKNTSVGP LYSGCRLTLL





13851
RPEKHEAATG VDTICTHRVD PIGPGLDREX LYWELSXLTX XIXELGPYXL





13901
DRXSLYVNGF XXXXXXXXTS TPGTSXVXLX TSGTPXXXPX XTSAGPLLVP





13951
FTLNFTITNL QYEEDMHHPG SRKFNTTERV LQGLLGPMFK NTSVGLLYSG





14001
CRLTLLRPEK NGAATGMDAI CSHRLDPKSP GLDREQLYWE LSQLTHGIKE





14051
LGPYTLDRNS LYVNGFTHRS SVAPTSTPGT STVDLGTSGT PSSLPSPTTA





14101
VPLLVPFTLN FTITNLQYGE DMRHPGSRKF NTTERVLQGL LGPLFKNSSV





14151
GPLYSGCRLI SLRSEKDGAA TGVDAICTHH LNPQSPGLDR EQLYWQLSQM





14201
TNGIKELGPY TLDRNSLYVN GFTHRSSGLT TSTPWTSTVD LGTSGTPSPV





14251
PSPTTAGPLL VPFTLNFTIT NLQYEEDMHR PGSRKFNATE RVLQGLLSPI





14301
FKNSSVGPLY SGCRLTSLRP EKDGAATGMD AVCLYHPNPK RPGLDREQLY





14351
WELSQLTHNI TELGPYSLDR DSLYVNGFTH QSSMTTTRTP DTSTMHLATS





14401
RTPASLSGPT TASPLLVLFT INCTITNLQY EEDMRRTGSR KFNTMESVLQ





14451
GLLKPLFKNT SVGPLYSGCR LTLLRPKKDG AATGVDAICT HRLDPKSPGL





14501
NREQLYWELS KLTNDIEELG PYTLDRNSLY VNGFTHQSSV STTSTPGTST





14551
VDLRTSGTPS SLSSPTIMXX XPLLXPFTLN FTITNLXYEE XMXXPGSRKF





14601
NTTERVLQGL LRPLFKNTSV SSLYSGCRLT LLRPEKDGAA TRVDAACTYR





14651
PDPKSPGLDR EQLYWELSQL THSITELGPY TLDRVSLYVN GFNPRSSVPT





14701
TSTPGTSTVH LATSGTPSSL PGHTXXXPLL XPFTLNFTIT NLXYEEXMXX





14751
PGSRKFNTTE RVLQGLLKPL FRNSSLEYLY SGCRLASLRP EKDSSAMAVD





14801
AICTHRPDPE DLGLDRERLY WELSNLTNGI QELGPYTLDR NSLYVNGFTH





14851
RSSFLTTSTP WTSTVDLGTS GTPSPVPSPT TAGPLLVPFT LNFTITNLQY





14901
EEDMHRPGSR RFNTTERVLQ GLLTPLFKNT SVGPLYSGCR LTLLRPEKQE





14951
AATGVDTICT HRVDPIGPGL DRERLYWELS QLTNSITELG PYTLDRDSLY





15001
VNGFNPWSSV PTTSTPGTST VHLATSGTPS SLPGHTAPVP LLIPFTLNFT





15051
ITDLHYEENM QHPGSRKFNT TERVLQGLLK PLFKSTSVGP LYSGCRLTLL





15101
RPEKHGAATG VDAICTLRLD PTGPGLDRER LYWELSQLTN SVTELGPYTL





15151
DRDSLYVNGF THRSSVPTTS IPGTSAVHLE TSGTPASLPG HTAPGPLLVP





15201
FTLNFTITNL QYEEDMRHPG SRKFSTTERV LQGLLKPLFK NTSVSSLYSG





15251
CRLTLLRPEK DGAATRVDAV CTHRPDPKSP GLDRERLYWK LSQLTHGITE





15301
LGPYTLDRHS LYVNGFTHQS SMTTTRTPDT STMHLATSRT PASLSGPTTA





15351
SPLLVLFTIN FTITNQRYEE NMHHPGSRKF NTTERVLQGL LRPVFKNTSV





15401
GPLYSGCRLT LLRPKKDGAA TKVDAICTYR PDPKSPGLDR EQLYWELSQL





15451
THSITELGPY TQDRDSLYVN GFTHRSSVPT TSIPGTSAVH LETSGTPASL





15501
PGHTAPGPLL VPFTLNFTIT NLQYEEDMRH PGSRKFNTTE RVLQGLLKPL





15551
FKSTSVGPLY SGCRLTLLRP EKRGAATGVD TICTHRLDPL NPGLDREQLY





15601
WELSKLTRGI IELGPYLLDR GSLYVNGFTH RTSVPTTSTP GTSTVDLGTS





15651
GTPFSLPSPA XXXPLLXPFT LNFTITNLXY EEXMXXPGSR KFNTTERVLQ





15701
TLLGPMFKNT SVGLLYSGCR LTLLRSEKDG AATGVDAICT HRLDPKSPGV





15751
DREQLYWELS QLTNGIKELG PYTLDRNSLY VNGFTHWIPV PTSSTPGTST





15801
VDLGSGTPSL PSSPTTAGPL LVPFTLNFTI TNLKYEEDMH CPGSRKFNTT





15851
ERVLQSLLGP MFKNTSVGPL YSGCRLTLLR SEKDGAATGV DAICTHRLDP





15901
KSPGVDREQL YWELSQLTNG IKELGPYTLD RNSLYVNGFT HQTSAPNTST





15951
PGTSTVDLGT SGTPSSLPSP TXXXPLLXPF TLNFTITNLX YEEXMXXPGS





16001
RKFNTTERVL QGLLXPXFKX TSVGXLYSGC RLTLLRXEKX XAATXVDXXC





16051
XXXXDPXXPG LDREXLYWEL SXLTXXIXEL GPYXLDRXSL YVNGFTHWIP





16101
VPTSSTPGTS TVDLGSGTPS SLPSPTTAGP LLVPFTLNFT ITNLKYEEDM





16151
HCPGSRKFNT TERVLQSLLG PMFKNTSVGP LYSGCRLTSL RSEKDGAATG





16201
VDAICTHRVD PKSPGVDREQ LYWELSQLTN GIKELGPYTL DRNSLYVNGF





16251
THQTSAPNTS TPGTSTVDLG TSGTPSSLPS PTSAGPLLVP FTLNFTITNL





16301
QYEEDMHHPG SRKFNTTERV LQGLLGPMFK NTSVGLLYSG CRLTLLRPEK





16351
NGAATGMDAI CTHRLDPKSP GLDREXLYWE LSXLTXXIXE LGPYXLDRXS





16401
LYVNGFXXXX XXXXTSTPGT SXVXLXTSGT PXXXPXXTXX XPLLXPFTLN





16451
FTITNLXYEE XMXXPGSRKF NTTERVLQGL LKPLFRNSSL EYLYSGCRLA





16501
SLRPEKDSSA MAVDAICTHR PDPEDLGLDR ERLYWELSNL TNGIQELGPY





16551
TLDRNSLYVN GFTHRSSMPT TSTPGTSTVD VGTSGTPSSS PSPTTAGPLL





16601
IPFTLNFTIT NLQYGEDMGH PGSRKFNTTE RVLQGLLGPI FKNTSVGPLY





16651
SGCRLTSLRS EKDGAATGVD AICIHHLDPK SPGLNRERLY WELSQLTNGI





16701
KELGPYTLDR NSLYVNGFTH RTSVPTTSTP GTSTVDLGTS GTPFSLPSPA





16751
TAGPLLVLFT LNFTITNLKY EEDMHRPGSR KFNTTERVLQ TLLGPMFKNT





16801
SVGLLYSGCR LTLLRSEKDG AATGVDAICT HRLDPKSPGL DREXLYWELS





16851
XLTXXIXELG PYXLDRXSLY VNGFXXXXXX XXTSTPGTSX VXLXTSGTPX





16901
XXPXXTXXXP LLXPFTLNFT ITNLXYEEXM XXPGSRKFNT TERVLQGLLR





16951
PVFKNTSVGP LYSGCRLTLL RPKKDGAATK VDAICTYRPD PKSPGLDREQ





17001
LYWELSQLTH SITELGPYTQ DRDSLYVNGF THRSSVPTTS IPGTSAVHLE





17051
TTGTPSSFPG HTEPGPLLIP FTFNFTITNL RYEENMQHPG SRKFNTTERV





17101
LQGLLTPLFK NTSVGPLYSG CRLTLLRPEK QEAATGVDTI CTHRVDPIGP





17151
GLDRERLYWE LSQLTNSITE LGPYTLDRDS LYVDGFNPWS SVPTTSTPGT





17201
STVHLATSGT PSPLPGHTAP VPLLIPFTLN FTITDLHYEE NMQHPGSRKF





17251
NTTERVLQGL LKPLFKSTSV GPLYSGCRLT LLRPEKHGAA TGVDAICTLR





17301
LDPTGPGLDR ERLYWELSQL TNSITELGPY TLDRDSLYVN GFNPWSSVPT





17351
TSTPGTSTVH LATSGTPSSL PGHTTAGPLL VPFTLNFTIT NLKYEEDMHC





17401
PGSRKFNTTE RVLQSLHGPM FKNTSVGPLY SGCRLTLLRS EKDGAATGVD





17451
AICTHRLDPK SPGLDREXLY WELSXLTXXI XELGPYXLDR XSLYVNGFXX





17501
XXXXXXTSTP GTSXVXLXTS GTPXXXPXXT XXXPLLXPFT LNFTITNLXY





17551
EEXMXXPGSR KFNTTERVLQ GLLXPXFKXT SVGXLYSGCR LTLLRXEKXX





17601
AATXVDXXCX XXXDPXXPGL DREXLYWELS XLTNSITELG PYTLDRDSLY





17651
VNGFTHRSSM PTTSIPGTSA VHLETSGTPA SLPGHTAPGP LLVPFTLNFT





17701
ITNLQYEEDM RHPGSRKFNT TERVLQGLLK PLFKSTSVGP LYSGCRLTLL





17751
RPEKRGAATG VDTICTHRLD PLNPGLDREX LYWELSXLTX XIXELGPYXL





17801
DRXSLYVNGF XXXXXXXXTS TPGTSXVXLX TSGTPXXXPX XTXXXPLLXP





17851
FTLNFTITNL XYEEXMXXPG SRKFNTTERV LQGLLXPXFK XTSVGXLYSG





17901
CRLTLLRXEK XXAATXVDXX CXXXXDPXXP GLDREXLYWE LSXLTXXIXE





17951
LGPYXLDRXS LYVNGFHPRS SVPTTSTPGT STVHLATSGT PSSLPGHTAP





18001
VPLLIPFTLN FTITNLHYEE NMQHPGSRKF NTTERVLQGL LGPMFKNTSV





18051
GLLYSGCRLT LLRPEKNGAA TGMDAICSHR LDPKSPGLDR EXLYWELSXL





18101
TXXIXELGPY XLDRXSLYVN GFXXXXXXXX TSTPGTSXVX LXTSGTPXXX





18151
PXXTXXXPLL XPFTLNFTIT NLXYEEXMXX PGSRKFNTTE RVLQGLLXPX





18201
FKXTSVGXLY SGCRLTLLRX EKXXAATXVD XXCXXXXDPX XPGLDREXLY





18251
WELSXLTXXI XELGPYXLDR XSLYVNGFTH QNSVPTTSTP GTSTVYWATT





18301
GTPSSFPGHT EPGPLLIPFT FNFTITNLHY EENMQHPGSR KFNTTERVLQ





18351
GLLTPLFKNT SVGPLYSGCR LTLLRPEKQE AATGVDTICT HRVDPIGPGL





18401
DREXLYWELS XLTXXIXELG PYXLDRXSLY VNGFXXXXXX XXTSTPGTSX





18451
VXLXTSGTPX XXPXXTXXXP LLXPFTLNFT ITNLXYEEXM XXPGSRKFNT





18501
TERVLQGLLX PXFKXTSVGX LYSGCRLTLL RXEKXXAATX VDXXCXXXXD





18551
PXXPGLDREX LYWELSXLTX XIXELGPYXL DRXSLYVNGF THRSSVPTTS





18601
SPGTSTVHLA TSGTPSSLPG HTAPVPLLIP FTLNFTITNL HYEENMQHPG





18651
SRKFNTTERV LQGLLKPLFK STSVGPLYSG CRLTLLRPEK HGAATGVDAI





18701
CTLRLDPTGP GLDREXLYWE LSXLTXXIXE LGPYXLDRXS LYVNGFXXXX





18751
XXXXTSTPGT SXVXLXTSGT PXXXPXXTXX XPLLXPFTLN FTITNLXYEE





18801
XMXXPGSRKF NTTERVLQGL LXPXFKXTSV GXLYSGCRLT LLRXEKXXAA





18851
TXVDXXCXXX XDPXXPGLDR EXLYWELSXL TXXIXELGPY XLDRXSLYVN





18901
GFTHRTSVPT TSTPGTSTVH LATSGTPSSL PGHTAPVPLL IPFTLNFTIT





18951
NLQYEEDMHR PGSRKFNTTE RVLQGLLSPI FKNSSVGPLY SGCRLTSLRP





19001
EKDGAATGMD AVCLYHPNPK RPGLDREQLY CELSQLTHNI TELGPYSLDR





19051
DSLYVNGFTH QNSVPTTSTP GTSTVYWATT GTPSSFPGHT XXXPLLXPFT





19101
LNFTITNLXY EEXMXXPGSR KFNTTERVLQ GLLXPXFKXT SVGXLYSGCR





19151
LTLLRXEKXX AATXVDXXCX XXXDPXXPGL DREXLYWELS XLTXXIXELG





19201
PYXLDRXSLY VNGFTHWSSG LTTSTPWTST VDLGTSGTPS PVPSPTTAGP





19251
LLVPFTLNFT ITNLQYEEDM HRPGSRKFNA TERVLQGLLS PIFKNTSVGP





19301
LYSGCRLTLL RPEKQEAATG VDTICTHRVD PIGPGLDREX LYWELSXLTX





19351
XIXELGPYXL DRXSLYVNGF XXXXXXXXTS TPGTSXVXLX TSGTPXXXPX





19401
XTXXXPLLXP FTLNFTITNL XYEEXMXXPG SRKFNTTERV LQGLLXPXFK





19451
XTSVGXLYSG CRLTLLRXEK XXAATXVDXX CXXXXDPXXP GLDREXLYWE





19501
LSXLTXXIXE LGPYXLDRXS LYVNGFTHRS FGLTTSTPWT STVDLGTSGT





19551
PSPVPSPTTA GPLLVPFTLN FTITNLQYEE DMHRPGSRKF NTTERVLQGL





19601
LTPLFRNTSV SSLYSGCRLT LLRPEKDGAA TRVDAVCTHR PDPKSPGLDR





19651
EXLYWELSXL TXXIXELGPY XLDRXSLYVN GFXXXXXXXX TSTPGTSXVX





19701
LXTSGTPXXX PXXTXXXPLL XPFTLNFTIT NLXYEEXMXX PGSRKFNTTE





19751
RVLQGLLXPX FKXTSVGXLY SGCRLTLLRX EKXXAATXVD XXCXXXXDPX





19801
XPGLDREXLY WELSXLTXXI XELGPYXLDR XSLYVNGFTH WIPVPTSSTP





19851
GTSTVDLGSG TPSSLPSPTT AGPLLVPFTL NFTITNLQYG EDMGHPGSRK





19901
FNTTERVLQG LLGPIFKNTS VGPLYSGCRL TSLRSEKDGA ATGVDAICIH





19951
HLDPKSPGLD REXLYWELSX LTXXIXELGP YXLDRXSLYV NGFXXXXXXX





20001
XTSTPGTSXV XLXTSGTPXX XPXXTXXXPL LXPFTLNFTI TNLXYEEXMX





20051
XPGSRKFNTT ERVLQGLLXP XFKXTSVGXL YSGCRLTLLR XEKXXAATXV





20101
DXXCXXXXDP XXPGLDREXL YWELSXLTXX IXELGPYXLD RXSLYVNGFT





20151
HQTFAPNTST PGTSTVDLGT SGTPSSLPSP TSAGPLLVPF TLNFTITNLQ





20201
YEEDMHHPGS RKFNTTERVL QGLLGPMFKN TSVGLLYSGC RLTLLRPEKN





20251
GAATRVDAVC THRPDPKSPG LDREXLYWEL SXLTXXIXEL GPYXLDRXSL





20301
YVNGFXXXXX XXXTSTPGTS XVXLXTSGTP XXXPXXTAPV PLLIPFTLNF





20351
TITNLHYEEN MQHPGSRKFN TTERVLQGLL RPLFKSTSVG PLYSGCRLTL





20401
LRPEKHGAAT GVDAICTLRL DPTGPGLDRE RLYWELSQLT NSVTELGPYT





20451
LDRDSLYVNG FTQRSSVPTT SIPGTSAVHL ETSGTPASLP GHTAPGPLLV





20501
PFTLNFTITN LQYEVDMRHP GSRKFNTTER VLQGLLKPLF KSTSVGPLYS





20551
GCRLTLLRPE KRGAATGVDT ICTHRLDPLN PGLDREQLYW ELSKLTRGII





20601
ELGPYLLDRG SLYVNGFTHR NFVPITSTPG TSTVHLGTSE TPSSLPRPIV





20651
PGPLLVPFTL NFTITNLQYE EAMRHPGSRK FNTTERVLQG LLRPLFKNTS





20701
IGPLYSSCRL TLLRPEKDKA ATRVDAICTH HPDPQSPGLN REQLYWELSQ





20751
LTHGITELGP YTLDRDSLYV DGFTHWSPIP TTSTPGTSIV NLGTSGIPPS





20801
LPETTXXXPL LXPFTLNFTI TNLXYEEXMX XPGSRKFNTT ERVLQGLLKP





20851
LFKSTSVGPL YSGCRLTLLR PEKDGVATRV DAICTHRPDP KIPGLDRQQL





20901
YWELSQLTHS ITELGPYTLD RDSLYVNGFT QRSSVPTTST PGTFTVQPET





20951
SETPSSLPGP TATGPVLLPF TLNFTITNLQ YEEDMHRPGS RKFNTTERVL





21001
QGLLMPLFKN TSVSSLYSGC RLTLLRPEKD GAATRVDAVC THRPDPKSPG





21051
LDRERLYWKL SQLTHGITEL GPYTLDRHSL YVNGFTHQSS MTTTRTPDTS





21101
TMHLATSRTP ASLSGPTTAS PLLVLFTINF TITNLRYEEN MHHPGSRKFN





21151
TTERVLQGLL RPVFKNTSVG PLYSGCRLTL LRPKKDGAAT KVDAICTYRP





21201
DPKSPGLDRE QLYWELSQLT HSITELGPYT QDRDSLYNVG FTQRSSVPTT





21251
SVPGTPTVDL GTSGTPVSKP GPSAASPLLV LFTLNGTITN LRYEENMQHP





21301
GSRKFNTTER VLQGLLRSLF KSTSVGPLYS GCRLTLLRPE KDGTATGVDA





21351
ICTHHPDPKS PRLDREQLYW ELSQLTHNIT ELGHYALDND SLFVNGFTHR





21401
SSVSTTSTPG TPTVYLGASK TPASIFGPSA ASHLLILFTL NFTITNLRYE





21451
ENMWPGSRKF NTTERVLQGL LRPLFKNTSV GPLYSGSRLT LLRPEKDGEA





21501
TGVDAICTHR PDPTGPGLDR EQLYLELSQL THSITELGPY TLDRDSLYVN





21551
GFTHRSSVPT TSTGVVSEEP FTLNFTINNL RYMADMGQPG SLKFNITDNV





21601
MKHLLSPLFQ RSSLGARYTG CRVIALRSVK NGAETRVDLL CTYLQPLSGP





21651
GLPIKQVFHE LSQQTHGITR LGPYSLDKDS LYLNGYNEPG LDEPPTTPKP





21701
ATTFLPPLSE ATTAMGYHLK TLTLNFTISN LQYSPDMGKG SATFNSTEGV





21751
LQHLLRPLFQ KSSMGPFYLG CQLISLRPEK DGAATGVDTT CTYHPDPVGP





21801
GLDIQQLYWE LSQLTHGVTQ LGFYVLDRDS LFINGYAPQN LSIRGEYQIN





21851
FHIVNWNLSN PDPTSSEYIT LLRDIQDKVT TLYKGSQLHD TFRFCLVTNL





21901
TMDSVLVTVK ALFSSNLDPS LVEQVFLDKT LNASFHWLGS TYQLVDIHVT





21951
EMESSVYQPT SSSSTQHFYL NFTITNLPYS QDKAQPGTTN YQRNKRNIED





22001
ALNQLFRNSS IKSYFSDCQV STFRSVPNRH HTGVDSLCNF SPLARRVDRV





22051
AIYEEFLRMT RNGTQLQNFT LDRSSVLVDG YSPNRNEPLT GNSDLPFWAV





22101
ILIGLAGLLG LITCLICGVL VTTRRRKKEG EYNVQQQCPG YYQSHLDLED





22151
LQ








Claims
  • 1-20. (canceled)
  • 21. A purified polypeptide consisting of 200 to 1000 amino acid residues and comprising at least 150 consecutive residues of residues 12,057-12,515 of SEQ ID NO:5.
  • 22. The purified polypeptide of claim 21 wherein the polypeptide comprises residues 12,057-12,515 of SEQ ID NO:5.
  • 23. The purified polypeptide of claim 22 wherein the polypeptide consists of 459 to 700 amino acid residues.
Parent Case Info

This application is a continuation-in-part of U.S. Provisional Application Ser. No. 60/284,175 filed Apr. 17, 2001, U.S. Provisional Application Ser. No. 60/299,380 filed Jun. 19, 2001, U.S. Non-Provisional application Ser. No. 09/965,738 filed Sep. 27, 2001, and U.S. Provisional Application Ser. No. 60/345,180. This application is a continuation-in-part of provisional application 60/427,045 (filed Nov. 15, 2002), all of which are hereby Specifically incorporated by reference. Applicants hereby specifically claims the benefit of these prior filed applications under 35 U.S.C. §119(e), and 120.

Provisional Applications (7)
Number Date Country
60427045 Nov 2002 US
60284175 Apr 2001 US
60299380 Jun 2001 US
60427045 Nov 2002 US
60345180 Dec 2001 US
60284175 Apr 2001 US
60299380 Jun 2001 US
Continuations (2)
Number Date Country
Parent 12455366 Jun 2009 US
Child 15420068 US
Parent 10715066 Nov 2003 US
Child 12455366 US
Continuation in Parts (5)
Number Date Country
Parent 10475117 Oct 2003 US
Child 10715066 US
Parent 09965738 Sep 2001 US
Child 10475117 US
Parent 10475117 Oct 2003 US
Child 12455366 US
Parent PCT/US02/11734 Apr 2002 US
Child 10475117 US
Parent 09965738 Sep 2001 US
Child PCT/US02/11734 US