Claims
- 1. An antibody molecule having specificity for carcinoembryonic antigen comprising a composite heavy chain and a complementary light chain, said composite heavy chain having a variable domain comprising the amino acid sequence of SEQ ID NO: 10.
- 2. An antibody molecule having specificity for carcinoembryonic antigen comprising a composite heavy chain and a complementary light chain, said composite heavy chain having a variable domain comprising the amino acid sequence of SEQ ID NO: 12.
- 3. An antibody molecule having specificity for carcinoembryonic antigen comprising a composite light chain and a complementary heavy chain, said composite light chain having a variable domain comprising the amino acid sequence of SEQ ID NO: 6.
- 4. An antibody molecule having specificity for carcinoembryonic antigen comprising a composite light chain and a complementary heavy chain, said composite light chain having a variable domain comprising the amino acid sequence of SEQ ID NO: 8.
- 5. An antibody molecule having specificity for carcinoembryonic antigen comprising a composite light chain and a composite heavy chain, said composite light chain having a variable domain comprising an amino acid sequence selected from SEQ ID NOs: 6 and 8 and said composite heavy chain having a variable domain comprising an amino acid sequence selected from SEQ ID NOs: 10 and 12.
- 6. The antibody molecule of claim 1, 2, 3, 4, or 5, wherein said antibody molecule is selected from the group consisting of a complete antibody molecule, Fab, Fab', (Fab').sub.2, Fv, and a single chain antibody.
- 7. The antibody molecule of claim 1, 2, 3, 4, or 5, further wherein said molecule has an effector or reporter molecule attached thereto.
- 8. The antibody molecule of claim 1, 2, 3, or 4 wherein the complementary chain is a chimeric chain.
- 9. A therapeutic or diagnostic composition comprising the antibody molecule of claim 1, 2, 3, 4, or 5 in combination with a pharmaceutically acceptable excipient, diluent, or carrier.
Priority Claims (1)
Number |
Date |
Country |
Kind |
9014932 |
Jul 1990 |
GBX |
|
Parent Case Info
This is a continuation of application Ser. No. 08/154,389, filed Nov. 17, 1993, now abandoned, which is a continuation of Ser. No. 07/847,995, filed Apr. 21, 1992, now abandoned, which is a continuation of PCT/GB90/01108 filed Jul. 5, 1991.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5530101 |
Queen et al. |
Jun 1996 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
0239400 |
Sep 1987 |
EPX |
Continuations (2)
|
Number |
Date |
Country |
Parent |
154389 |
Nov 1993 |
|
Parent |
847995 |
Apr 1992 |
|