Genetic analysis of peyer's patches and M cells and methods and compositions targeting peyer's patches and M cell receptors

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of U.S. provisional application No. 60/281,387 filed Apr. 4, 2001, and U.S. provisional application No. 60/302,591 filed Jul. 2, 2001.

FIELD OF THE INVENTION

[0002] This invention relates to the genetic analysis of M cells and methods and compositions targeting M cell receptors.

BACKGROUND OF THE INVENTION

[0003] The Peyer's patch of the intestinal lining is a specialized tissue that allows the immune system to identify foreign antigens that require an immune response. It is also a potential pathway for orally delivered drugs to cross the intestinal barrier into the bloodstream. Central to these properties are M cells, which populate the patch's epithelial sheet. In view of the importance of the Peyer's patch and its M cells for the immune response and drug delivery, it is desirable to identify the cell proteins important for these phenomena. It is also desirable to increase the amounts of such important proteins in order to either facilitate the immune response and drug delivery or promote the conversion of non-M cells to M cells.

[0004] Similarly, it is important to identify and further decrease the levels of proteins whose absence or down-regulation in expression facilitates the immune response and drug delivery, or promotes the conversion of non-M cells to M cells.

BRIEF SUMMARY OF THE INVENTION

[0005] Increasing the Levels of a Protein or Antigen-Protein Combination

[0006] In a first general aspect, the invention is a method of increasing the levels of a protein in a Peyer's patch cell, said method comprising delivering to said cell a nucleic acid coding for a protein, wherein absent said increase, the levels of said protein or its mRNA is greater than in a non-Peyer's patch cell.

[0007] Peyer's patch cells of particular interest are M cells. The levels of a protein or its mRNA in Caco-2 cells co-cultured with Raji B cells are considered herein to be representative of such levels in a human Peyer's patch M cell. Monoculture Caco-2 cells are considered herein to be an appropriate non-Peyer's patch cell for purposes of comparison of such protein or mRNA levels.

[0008] The levels of a protein or its mRNA in rat Peyer's patch epithelial cells can be compared to their respective levels in a culture of rat normal gut epithelial cells. Absent evidence to the contrary, results of rat cells are assumed to be predictive of the results in human cells.

[0009] The presence of Increased levels of an mRNA, and therefore presumptively its protein, are indicated in the Table 2 and 3 by a ** a *, or an expression Fold Change greater than 1.00. Preferred are those indicated by a ** or an expression Fold Change greater than 2.00. Most highly preferred are those indicated by a **. The presence of decreased levels of an mRNA, and presumptively its protein, are indicated by a minus sign (−) or an expression Fold Change less than 1.00. Preferred targets are those indicated by a minus sign or an expression Fold Change less than 0.50.

[0010] In embodiments of particular interest, the protein is a receptor, a transporter, cell surface antigen, or cell adhesion molecule, especially a receptor. In other embodiments of particular interest, the protein is selected from the group consisting of nucleoside diphosphate kinases and member of the 14-3-3 family.

[0011] In the methods of greatest interest, the nucleic acid is delivered to a human cell. There are many delivery options, one of which is to deliver it by the oral route with the cell in a human, another to deliver it to a cell outside a human.

[0012] In an important variation of the method, a nucleic acid coding for a tumor antigen or foreign peptide is also delivered to the Peyer's patch cell. The purpose of this aspect of the invention is to improve the immune response to a tumor antigen or the foreign peptide. Normally, therefore, the foreign peptide will be that of a virus or infectious microorganism. A tumor antigen is one that is more abundant in a tumor cell than its normal counterpart.

[0013] Decreasing the Levels of a Protein

[0014] Another general aspect of the invention is a method of decreasing the levels of a protein in a Peyer's patch cell, said method comprising delivering to said cell an anti-sense nucleic acid molecule, a ribozyme nucleic acid molecule, an RNA interference (RNAi) nucleic acid molecule, said anti-sense, ribozyme or RNAi nucleic acid being complementary to a sequence of at least 10 nucleotides of the mRNA for said protein, wherein absent said anti-sense nucleic acid molecule, ribozyme or RNAi nucleic acid, the levels of said protein or its mRNA are less than in a non-Peyer's patch cell. More preferably the anti-sense nucleic acid is complementary to a sequence of at least 15 nucleotides of the mRNA of the protein, and most preferably to a sequence of at least 30 nucleotides of the mRNA of the protein. It is preferred that the protein is coded for by a gene with an expression Fold Change denoted by a minus sign (−) or an expression Fold Change less than 0.50.

[0015] In a particular embodiment, the latter method comprises delivering to said cell an anti-sense nucleic acid molecules, a ribozyme or RNAi nucleic acid molecules, said anti-sense, ribozyme or RNAi nucleic acid being complementary to a sequence of at least 10 nucleotides of the mRNA for at least 5 different proteins, wherein absent said anti-sense, ribozyme or RNAi nucleic acid molecule, the levels of each of said proteins or its mRNA are less than in a non-Peyer's patch cell.

[0016] Alternatively described, the latter invention is a method of deceasing the levels of a protein in a Peyer's patch cell, said method comprising delivering to said cell an anti-sense nucleic acid molecule, ribozyme or RNAi nucleic acid molecules, said anti-sense, ribozyme or RNAi nucleic acid forming a double-stranded molecule with part or all of the mRNA for said protein, wherein absent said anti-sense, ribozyme or RNAi nucleic acid molecule, the levels of said protein or its mRNA are less than in a non-Peyer's patch cell.

[0017] Cells of the Invention

[0018] A human or rat cell to which any of the above methods in this Brief Summary of the Invention section has been applied, or the progeny of said cell, is also an aspect of the present invention.

[0019] Delivery Enhancement using a Targeting Ligand which Targets a Receptor, a Transporter or a Cell-Surface Molecule Expressed on Surface of M Cells or Pever's Patch Tissue Cells

[0020] In another general aspect, the invention is a method of targeting an antigen or a drug delivery vehicle containing an antigen, or a drug delivery vehicle containing an antigen and adjuvant, or a drug delivery vehicle containing a drug, or a viral vector, or a bacterio-phage vector such as, but without limitation M13 or Fd, or a bacterial vector or a gene delivery vector expressing an antigen of interest, or a viral vector, or a bacterio-phage vector such as, but without limitation M13 or Fd, or a bacterial vector or a gene delivery vector expressing a gene product(s) to M cells of Peyer's patch tissue, by targeted delivery to receptors, or to transporters or to other cell surface proteins which are found to be expressed on the cell surface of M cells or other cells found within Peyer's patch tissue, or which are found to be differentially expressed on these cells. Said gene product(s) coded by the viral vector, or a bacterio-phage vector such as, but without limitation M13 or Fd, or a bacterial vector or a gene delivery vector regulate the function of Peyer's patch cells to M cell phenotype or regulate M cell function to increase their immuno-surveillance or antigen presentation to the mucosal immune system.

[0021] In one embodiment, a phage display library such as M13 or Fd which express random peptide sequences on the surface of the phage, coded by example gene III or gene VII of M13 or Fd bacteriophage, can be screened by in vivo panning against example Peyer's patch tissue found in vivo in the GIT, in order to discover and identify phage or targeting ligands which specifically target M cells or Peyer's patch tissue in vivo in the GIT; such phage which target M cells and Peyer's patch tissue can subsequently be genetically engineered to encode a gene or genes of interest such as a DNA vaccine gene, a gene coding for an antigen of interest together with gene(s) which modify M cell function and which enhance the immuno-responsiveness of the M cells to the antigen or DNA vaccine product coded by the genetically engineered bacteriophage genome.

[0022] Delivery Enhancement using Transport Enhancing Proteins

[0023] Another invention disclosed herein is a method for enhancing transport of a drug through the gastrointestinal tract, said method comprising orally administering said drug in a composition that comprises a transport-enhancing protein, said transport-enhancing protein selected from the group consisting of human serum albumin (HSA), clusterin, T-cell surface glycoprotein CD5 precursor, HSP84, and Ca2+-dependant phospholipase A2 (Ca2+ pla2), or a homolog that has at least 80% amino acid identity with said transport-enhancing protein over a length of said transport-enhancing protein identical to the homolog. In a preferred embodiment, the homolog has at least 90% amino acid identity with the transport-enhancing protein over a length of the transport-enhancing protein identical to the homolog. In a more preferred embodiment, the transport-enhancing protein is selected from the group consisting of human serum albumin (HSA), clusterin, T-cell surface glycoprotein CD5 precursor, HSP84, and Ca2+ pla2.

[0024] Method of Delivering a Vaccine to a Target Cell

[0025] Further invention disclosed herein is a method of delivering a vaccine to a target cell, said method comprising utilizing as the target cell a Peyer's patch cell in which a protein or mRNA is upregulated.

[0026] Method of Decreasing the Levels of a Protein

[0027] Yet, another invention disclosed herein is a method of decreasing the levels of a protein in a Peyer's patch cell, said method comprising delivering to said cell a DNA molecule coding for an anti-sense nucleic acid molecule, a ribozyme nucleic acid molecule, an RNA interference nucleic acid molecule (RNAi), said anti-sense molecule, ribozyme or RNAi nucleic acid being complementary to a sequence of at least 10 nucleotides of the mRNA for said protein, wherein absent said anti-sense molecule, ribozyme or RNAi nucleic acid, the levels of said protein or its mRNA is less than in a non-Peyer's patch cell.

[0028] Method of Increasing the Extent to which the Function of a Protein is Carried Out

[0029] Another invention disclosed herein is a method of increasing the extent to which the function of a protein is carried out in a Peyer's patch cell, said method comprising delivering to said cell a nucleic acid coding for said protein, wherein absent said delivery, the level of said protein or its mRNA is greater in said cell than in a non-Peyer's patch cell.

[0030] Chimeric Protein that Comprises Two or More Segments, each of said Segments Enhancing a Different Step in the Peptide Transport Process

[0031] Another invention disclosed herein is a chimeric protein that comprises two or more segments, each of said segments enhancing a different step in the peptide transport process, said steps selected from the group consisting of binding to a cell such as an M cell, transporting the peptide into the cell such as an M cell, presenting the chimeric protein to a protein processing pathway within a cell such as an M cell in order to maximise processing in a way to optimize presentation of the processed chimeric peptides to epitopes suitable for immune activation, transporting the peptide through the cell such as an M cell, and transporting the peptide out of the cell such as an M cell to an underlying immune cell such as a B-cell or T-cell.

[0032] Delivery Enhancement using Calreticulin and other Proteins

[0033] Another method disclosed herein is a method to facilitate intracellular trafficking of an antigen that has been orally delivered by itself or as part of a composition or particle, said method comprising administering calreticulin.

[0034] Related to the latter invention is a chimeric protein comprising the amino acid sequences for (1) calreticulin, rab family proteins and and/or a ribosomal protein, and (2) a second polypeptide. Also related is a method of administering a polypeptide, where said polypeptide is part of the chimeric protein and wherein said chimeric protein is orally administered.

DETAILED DESCRIPTION OF THE INVENTION

[0035] The present invention and the related research were intended to improve targeted vaccine delivery and targeted gene delivery methods, especially as they relate to Peyer's patch cells. In significant part, this was achieved by identifying proteins whose up-regulation or down-regulation would indicate their possible or probable role in cellular functions important to vaccine and or drug delivery. In some cases, such as receptors, the proteins are important from the point of view of cell specificity during the delivery process. In many cases, the proteins have functions that are important after the vaccine or drug enter the cell.

[0036] Closely related to those inventions and research goals, was the concept that in M cells there would be proteins that, as compared to M cell precursors, were up-regulated or down-regulated. The identification of such proteins provides a strategy for altering M cell precursors so as to shift their phenotype toward that of M cells.

[0037] As indicated, one aim of the research related to the present invention was to determine if there were detectable differences in protein/gene expression between: (1) Peyer's patch (PP) and non-Peyer's patch (NPP) rat gastrointestinal tract (GIT) tissue and (2) M cell enriched follicle-associated epithelium of Peyer's patch (PP FAE) tissue. This was done with a view to finding novel or highly expressed ligand targeting sites on the Peyer's patch or M cells as well as other protein relevant to the delivery of drugs across the GIT.

[0038] This invention is based in part on the discovery of over-expression of a range of genes in Peyer's patch (PP) tissue from rat small intestine in comparison to normal non-Peyer's patch (NPP) small intestine tissue.

[0039] This invention is also based on the discovery of over-expressed genes in co-cultures of Caco-2 cells. The idea was to use genetic mapping of the M cell co-culture, e.g. Caco-2 cells co-cultured with Raji cells versus a monolayer of Caco-2 cells, to ascertain the differences in epithelial gene expression between M cells and enterocytes. It became immediately apparent that some of these gene products are going to be unique apical membrane proteins (e.g. receptors, transporters, adhesion proteins) in M cells. By examining the differences between M cells and enterocytes in vitro and in vivo, one could identify key targets that can be used to generate M cell specific ligands. These ligands can then be used for targeting oral vaccines in particles.

[0040] The identification of over-expressed ribosomal proteins or homologues/related proteins thereof indicates a generally higher protein turnover or protein synthesis capacity in PPs or a possible role for such ribosomal proteins (or homologues thereof) in other cellular functions such as protein chaperoning, endocytosis, trafficking of proteins/antigens/particulates/viruses uptaken from the lumen of the gastrointestinal tract (GIT) and/or from the M cells to underlying immune cells, antigen presenting cells, dendritic cells, B cells, other cell types.

[0041] The identification of a series of transcription factors (TFs) that are over-expressed in PP tissue versus the control enterocyte GIT tissue is considered herein to indicate a role for such TFs in the development of M cell phenotype, in conferring M cell phenotype and/or in programming M cells to prime other downstream cellular events leading to a better or more efficacious immune outcome following antigen presentation. The co-delivery of genes coding for such TFs with either antigens themselves and/or with gene(s) coding for antigen(s) of question to M cells and/or PP tissue following oral administration provides the basis for a more efficacious and pronounced immune outcome when the TF coding genes are key or vital for driving M cells/PP tissue to an effective immune outcome.

[0042] The general over-expression of a number of proteins species in PPs versus NPPs, both membrane and cytosolic-associated was also determined by a novel technique of enrichment and M cell selection following enrichment of the follicle-associated epithelium (FAE) of Peyer's patch (PP FAE) by ethylene-diamine tetra-acetic acid (EDTA) extraction and recovery of M cells/PP FAE. Such novel or differentially expressed proteins have significant implications for the use of this protein expression information and methods of selection/enrichment of M cells/PP tissue for the targeting of drug/vaccine uptake to Peyer's patches. Among proteins found to be over expressed in rat PP tissue following this enrichment technique was the human serum albumin homolog which is considered here to have implications for drug/cargo transport from the GIT either into oracross intestinal tissue including PP tissue and systemic delivery of same to the blood.

Incorporation by Reference

[0043] All references cited herein are incorporated herein by reference in their entireties.

[0044] All GenBank records specified bytheiraccession numbers are incorporated herein by their entireties.

[0045] The GenBank amino acid sequences and nucleotide sequences specified by their GenBank ID number are incorporated by reference herein. All GenBank records corresponding to those ID numbers are incorporated herein in their entirety. Absent a date specifying the date of the record, the date of the record is the filing date of this application.

[0046] Many of GenBank sequences specified by their GenBank ID numbers are reproduced herein in the section “Amino acid sequences and nucleotide sequences corresponding to selected GenBank ID numbers.” The CDS line refers to the exon(s).

[0047] Any GenBank ID numbers specified herein, absent a decimal point and an integer following that decimal point, is for GenBank version 1 of that sequence. Any GenBank ID number that has a decimal point and an integer following it is the GenBank version number.

[0048] The invention will be illustrated in more details with reference to the following Examples, but it should be understood that the present invention is not deemed to be limited thereto.

EXAMPLES

Example 1

Preparation of Cytosolic (S100) and Membrane (P100) Proteins from Rat PP and NPP Tissues

[0049] Protein samples were prepared from PP and NPP tissue extracted from freshly sacrificed rats. These protein samples underwent electrophoresis on denatured SDS-PAGE gels and were stained using two different standard proteins Commassie Blue stains. Subsequently, fresh PP and NPP tissue samples were fractionated into cytosolic (S100) and membrane (P100) proteins and these samples were also electrophoresed on SDS-PAGE in order to compare S100 and P100 fractions in both PP and NPP tissues.

Example 2

Preparation of GIT Tissue or Co-Culture Cell Membrane (P100) and Cytosolic (S 100) Fractions

[0050] The fractions were prepared using the following procedure:

[0051] 1. Scrape the co-culture cells into PBS and pool cells into a universal.

[0052] 2. Centrifuge the cells for 5 minutes at 1,500 rpm.

[0053] 3. Remove the supernatant.

[0054] 4. Re-suspend the cell pellet in 3 volumes of ice-cold HED buffer, and allow it to swell for 5 minutes on ice.

[0055] 5. Homogenize the cells for 30 seconds.

[0056] 6. Centrifuge the homogenate in hard walled tubes at 40,000 rpm for 45 minutes at 4° C. in a Beckmann Ultra Centrifuge (rotor Ti90).

[0057] 7. Remove the supernatant (S 100) and re-suspend the pellet (P100) in 3 volumes of HEDG buffer, before centrifugation again at 1000 rpm for 2 min. Remove the supernatant and store on ice. Repeat the procedure and add the second supernatant to the first.

[0058] 8. Determine the protein concentration (using the Bio-Rad protein assay).

[0059] 9. All fractions were stored at −80° C.

[0060] The following reagents were used in the above methods: HED buffer (20 mM HEPES pH 7.67), 1 mM EGTA, 0.5 mM dithiothreitol, 1 mM phenylmethylsulphonyl fluoride (PMSF):

1HEPES (pH to 7.67)0.5206gEGTA38.04mgDithiothreitol7.71mgDistilled waterto 100ml

[0061] 10 μl PMSF stock solution was added to 1 ml of buffer prior to use.

[0062] HEDG buffer (the same as HED buffer plus 100 mM NaCl, 10% glycerol)

2NaCl0.584gGlycerol11.4mlHEPES (pH to 7.67)0.5206gEGTA38.04mgDithiothreitol7.71mgDistilled waterto 100ml

[0063] 10μl PMSF stock solution was added to 1 ml of buffer prior to use.

[0064] PMSF(100 mM) stock solution

3PMSF17.42 mgIsopropanol

Example 3

Isolation of Epithelial Sheaths from Rat Pever's Patch and Non-Pever's Patch Tissue

[0065] The M cell is a very elusive cell type, at least in terms of isolating a purified population. Previous attempts have found that when M cells are separated and purified and put into culture they very quickly lose their characteristic morhphology and probably gene/protein expression profile. In many cases this is due to the length of time taken to isolate and purify the cells from the very homogenous mix of cells in a Peyer's patch. We desired a quick and routine method to enrich for M cells is Peyer's patch samples. M cells are only contained in the epithelium of Peyer's patches, the so-called follicle associated epithelium (FAE), while underneath the epithelial layer lays all the B and T lymphocytes, dendritic cells etc. So by isolating the epithelium away from the rest of the Peyer's patch dome, we are greatly enriching it for the M cell population. Previously, treatment of mouse intestinal tissue with EDTA was shown to cause separation of the epithelium as a sheet from the rest of the tissue, allowing for it's specific isolation (Bjerknes M and Cheng H (1981). Methods for the isolation of intact epithelium from the mouse intestine. Anat. Rec., (199):565). This method was adapted for the isolation of FAE from rat Peyer's patch. Control epithelium from normal gut tissue (no Peyer's patches) was used as a control.

[0066] Epithelial sheaths were prepared using EDTA method comprising the following steps:

[0067] 1. Sacrifice the rats (Wistar) by cervical dislocation.

[0068] 2. Remove the entire length of the GIT tract from (but not including) the stomach to the caecum and place in a dish of PBS (at room temperature).

[0069] 3. Excise the Peyer's patches, taking care to remove as much normal non-PP GI tissue as is visible. Rinse briefly in PBS.

[0070] 4. Also take samples of normal non-Peyer's (N PP) tissue close to the patches, rinse in PBS and treat as for the PPs (steps 5-9,11-12).

[0071] 5. Pool the PP's from the entire GI section in Hank's Buffered Saline Solution (HBSS, Gibco Life Sciences) with 0.011 M glucose and 25 mM Hepes.

[0072] 6. When pooling is complete, place PP sections into 15-20 ml of HBSS (with 0.011M glucose and 25 mM Hepes) along with 40 mM of EDTA into a small conical flask.

[0073] 7. Add a stirrer bar to the flask, place on a stirring plate and spin the PP's for 15 min at RT.

[0074] 8. After 15 minutes pipette the PP solution vigorously with a wide-bore 3 ml plastic pasteur pipette.

[0075] 9. Strain the supernatant through a 100 micron nylon cell strainer (from FALCON™, 352360).

[0076] 10. Move the filter to another 50 ml tube and wash out the residue material on the filter with HBSS (with 0.011M glucose and 25 mM Hepes, no EDTA). This residue contains the majority of the PP dome epithelial sheaths.

[0077] 11. Centrifuge the PP residue material at 3000 rpm for 5 min. Also centrifuge the NPP tissue supernatant at 3000 rpm for 5 min.

[0078] 12. Snap freeze the cell pellets and store at −70° C.

Example 4

Identification of Over-Expressed Proteins in Enriched M cells/PP FAE Cells

[0079] Epithelial cell layers of Wistar rat PP (representing enriched M cells/PP FAE cells) and normal villi were extracted using EDTA as described in Example 3 above. Epithelial layers from numerous Patches and rats were pooled and the protein isolated into either cytosolic and membrane fractions following centrifugal separation. 2D gel electrophoresis (between isoelectric points pH 3.5 to 10) was performed on 50 μg of each fraction, wherein the gels were silver stained. The gels were overlaid, and numerous differentially expressed proteins between the membrane fractions of PP and normal villi epithelia were observed. Further, protein samples underwent a second 2D gel electrophoresis, this time the gel was stained with a “special” silver stain, that did not inhibit the mass spectrometry analysis of individual spots. The differentially expressed proteins were identified and highlighted by gel overlay.

[0080] Thirty-seven protein spots were identified that were increased in PP over villi epithelial membrane fractions. Of these, 16 spots (the most highly over-expressed) were chosen for mass spectrometry analysis. The spots were digested with endoproteinase Lys-C/trypsin (8:1 ratio) and analyzed on a MALDI-MS. The spots, however, gave very poor spectra and only 4 of the 16 were identifiable. These were:

[0081] serum albumin;

[0082] calreticulin;

[0083] 14-3-3 zeta (tentative ID; mouse); and

[0084] nucleoside diphosphate kinase B.

[0085] One protein showed homologyto human serum albumin (HSA). Work byA. Fasano at Maryland had suggested that Zonulin, the human homologue of ZOT, showed sequence homology to human serum albumin (85% homology across the limited sequence available from the Fasano's work). Given our finding that a protein differentially expressed in rat PP tissue shows homology to HSA, we propose that HSA (or a homologue or splice variant thereof) is involved in drug transport in the GIT, in particular Peyer's patch tissue of the GIT.

[0086] Calreticulin is a 46-kDa Ca (2+)-binding chaperone of the endoplasmic reticulum membranes. This protein binds Ca (2+) with high capacity, affects intracellular Ca (2+) homeostasis, and functions as a lectin-like chaperone. Given the over-abundance of expression of this protein in epithelial layers selected from PP tissue and the role of this protein as a lectin-like chaperone, we propose that this protein is a valuable protein target to aid or facilitate the intracellular trafficking of antigens or antigens in particles following targeted delivery to M cells or PP tissue. Proteins comprising chimerics of calreticulin plus a polypeptide with an antigen of choice would therefore prove valuable in that regard.

[0087] Members of the 14-3-3 protein family have been identified as regulatory elements in intracellular signaling pathways and cell cycle control. There had been reports that 14-3-3 protein can be used as a marker for Creutzfeldt-Jacob Disease (CJD) in cerebrospinal fluid (CSF). It is proposed that this protein or the gene coding for it is valuable in the control of the M cell phenotype, and as a result it would be advantageous to co-deliver that protein or gene with a protein, antigen, or DNA vaccine.

[0088] Nucleoside diphosphate kinases (NDP kinases) form a family of oligomeric enzymes present in all organisms. Eukaryotic NDP kinases are hexamers composed of identical subunits (approximately 17 kDa). A distinctive property of human NDPK-B is its ability to stimulate gene transcription. This property is independent of its catalytic activity and is possibly related to the role of this protein in cellular events including differentiation and tumor metastasis. Given our discovery of the increased expression of nucleoside diphosphate kinase B in M cell enriched PP FAE cells, we propose the importance of this protein in determining or controlling M cell phenotype, in M cell development, and optimal activation or priming of the mucosal immune system.

Example 5

Gene Expression Analysis of Rat PP and NPP Tissue Samples

[0089] In addition to the proteomic studies highlighted above, PP and NPP tissue samples were sent for gene expression analysis to CLONTECH Laboratories Inc. (a division of Becton Dickinson (BD) Biosciences) who then extracted RNA from the tissues to probe on ATLAS™1.2 rat arrays. The data containing differential expression levels of 1,200 genes many of which are presented in Table 1 below. The data show over-expression of many proteins. In Table 1, over-expressed genes are shown in bold and italicized.

[0090] In Table 1, “N/C” means not calculated due to manually-determined inconsistencies in one or both spots, and “?” means low confidence level (small difference).

[0091] Also, over-expressed genes from Table 1 that had a fold change above 0, as well as over-expressed genes are shown in Table 2 below with corresponding GenBank accession numbers for rat and human origin.

[0092] Based on the results (ratio PP/Normal epithelial tissue) in Table 1, the following proteins are of the particular interest: clusterin, T-cell surface glycoprotein CD5 precursor, HSP84, Ca2+-dependant phospholipase A2 precursor, ribosomal proteins S12, S11, L12, L11, S29, S19, L21, L19, L13, L44, and L36A.

[0093] In addition a series of genes coding for different TFs was noted including the following:

[0094] Jun-B; c-jun related TF,

[0095] Jun-D; c-jun related TF,

[0096] STAT 3-signal transducer and activator of transcription 3,

[0097] NF-kappaβ Tf p105 subunit,

[0098] CREB active TF,

[0099] New england deaconess TF,

[0100] C-jun proto-oncogene; TF AP-1; RJG-9,

[0101] S-myc proto-oncogene; myc related,

[0102] Nm23-M2; nucleoside diphosphate kinase B; metastasis reducing protein,

[0103] NDK-B; nucleoside diphosphate kinase B; metastasis reducing protein,

[0104] Lim-2; embryonic motor neuron topographic organizer; homeobox protein LIM-2, and

[0105] C-est-I proto-oncogene; p54.

[0106] TF coding genes such as these are considered here to be important in the development of M cell phenotype and in priming the immune system. Their co-delivery or co-targeting with DNA vaccine genes and/or with vaccines is expected to enhance activation of mucosal immunity to the co-delivered DNA vaccine and/or antigen by virtue of their priming of the cells to give a better mucosal immunity outcome.

4TABLE 1GENE EXPRESSION DATA FROM ATLAS 1.2 RAT ARRAY ANALYSISSpot Intensity#coordinatePP1NE1RATIODifferenceGENE1A03c3860.16−32T-cell surface glycoprotein CD5 precursor; lymphocyte glycoprotein LY12A03g31571.8426CD4 homologue, W3/25 antigen3A04f20723.6052signal transducer CD24 precursor; heat stable antigen (HSA); nectadrin4A04i17402.3523CD2, membrane glycoprotein, T-cell marker5A04i8344.2526scavenger receptor class B type I6A04m16311.9415SR13 myelin protein, peripheral myelin protein 22 (PMP-22), CD25 protein7A05a4174.2513glutamyl aminopeptidase A8A05i52290.56−23I-kB (I-kappa B) alpha chain; RL/IF-1 gene product9A05m6183.0012interferon regulatory factor 1 (IRF1)10A06a7213.0014LIM domain protein CLP36, homologous to rat RIL11A06c152780.51−74Gax. growth-arrest-specific protein12A07c42240.57−18G1/S-specific cyclin D3 (CCND3)13A07l1730.18−14M-phase inducer phosphatase 2 (MPI2); cell division control protein 25 B (CDC25B)14A07n37200.54−17p55cdc; cell division control protein 2015A08e56240.43−32prothymosin-alpha (PTMA)16A08n321053.2873antigen peptide transporter 117A09g13362.7723proteasome delta subunit precursor; macropain delta; multicatalytic endopeptidasecomplex delta;18A09i15271.8012proteasome component C13 precursor; macropain subunit C13; multicatalyticendopeptidase19A09j3418932.62552apolipoprotein A-I precursor (APO-AI)20A09k7272310.04651apolipoprotein A-IV precursor (APO-AIV)21A11l11313.0012ErbB3 EGF receptor-related proto-oncogene; HER322A12c21482.2927A-raf proto-oncogene23A12i19452.3726rac-alpha serine/threonine kinase (RAC-PK-alpha); protein kinase B (PKB), AKT124A13k208600.29−148HSP84; HSP90-beta; heat shock 90 kD protein25A14c7385.4331glutathione S-transferase Ya subunit (GST YA); liqandin subunit 1 alpha26A14d651622.4997microsomal glutathione S-transferase (GST12; MGST1)27A14e941601.7066glutathione S-transferase Yb subunit; GST subunit 4 mu (GSTM2)28A14q1292652.05136glutathione S-transferase P subunit; GST subunit 7 pi (GST7-7)29A14n7192.7112NADPH-cytochrome P450 reductase (CPR); POR30B01h1212071.7186copper-zinc-containing superoxide dismutase 1 (Cu—Zn SOD1)31B02f4256.2521fructose (glucose) transporter32B05k13362.7723sodium channel SCNB2, beta 2 subunit, brain33B06d28120.43−16potassium channel, inward rectifier 1134B07k2189.0016proton-coupled dipeptide cotransporter35B08b591813.07122fibroblast ADP/ATP carrier protein; ADP/ATP translocase 2, adenine nucleotidetranslocator 236B09i7436.1436sodium-glucose cotransporter 137B09l401152.8875Na+/K+ ATPase alpha 1 subunit38B09n43781.8135vacuolar ATP synthase 16-kDa proteolipid subunit, ATP6C; MVP; ATPL39B10b10787.8068sodium/potassium-transporting ATPase beta 1 subunit (ATP1B1)40B12e10686.8058urate transporter/channel41B12f1432972.08154ATP synthase lipid-binding protein P1 precursor, ATPase protein 9, ATP5G142B12q211125.3391ATP synthase, subunit c, P2 gene43B12m18382.1120annexin IV(ANX4); lipocortin IV;36-kDa zymogen granule membrane-associatedprotein (ZAP36)44B13f371273.4390lipocortin 245B14d593265.53267fatty acid-binding protein (liver; L-FABP); Z-protein; squalene - & sterol-carrierprotein (SCP); P1446B14f491573.20108fatty acid-binding protein (intestinal; I-FABP; FABPI)47C02f19784.1159fructose-bisphosphate aldolase B (ALDOB); liver-type aldolase48C02g37762.0539fructose-bisphosphate aldolase A (ALDOA); muscle-type aldolase49C02j15302.0015testis fructose-6-phosphate 2-kinase/fructose 2,6-biphosphate(testis 6PF-2-K/fru-2,6-P2ase); 6-50C02n60411231.86519cytochrome c oxidase subunit Vb & Vla precursor (COX5B)51C03a9202.2211cytochrome B5 (CYB5)52C03e651382.1273mitochondrial hydroxymethylglutaryl-CoA synthase precursor (HMG-CoA synthase);3-hydroxy-3-53C03f1777604.29583cytochrome oxidase, subunit I, Sertoli cells54C03q27471.7420ATPase, subunit F, vacuolar (vatf)55C03i64110871.70446cvtochrome c oxidase, subunit IV, mitochondrial56C03l461473.20101cytochrome c oxidase, subunit Va, mitochondrial57C03l3171800.57−137cytochrome c oxidase, subunit VIIIh58C04b1893511.86162mitochondrial ATP synthase beta subunit precursor (ATP5B)59C04q231275.52104creatine kinase, ubiquitous, mitochondrial60C06c6528.6746fatty acid amide hydrolase61C06j731752.40102cytochrome P450 17 (CYP17), P450C17, CYPXVII, steroid 17-alpha-hydroxylase/17,20lyase62C07i9515.6742cytochrome P-450 4F1, hepatic tumour63C07l19392.0520cytochrome P-450 4F464C08a17331.9416cytochrome P-450 4F565C08l8243.0016adenylate kinase 366C08m32652.0333cAMP-dependent protein kinase type I-alpha regulatory chain67C09e7304.2923glutathione synthetase (GSH synthetase; GSH-S; GSS). glutathione synthase68C10e25100.40−15carbonic anhydrase 469C10j1990.47−10alkaline phosphatase70C10k2150.24−16dopamine beta-hydroxylase71C10l29110.38−18acetylcholinesterase, T subunit, glycolipid-anchored72C10m2284451.95217NADP+ alcohol dehydrogenase; aldehyde reductase (ALR); 3-dG-reducing enzyme73C11b19331.7414calcium bindinq protein 2 (CABP2), endoplasmic reticulum stress protein (ERP72);protein disulfide74C11d97550.57−4260S ribosomal protein L44; L36A75C11e17285270.30−120140S ribosomal protein S1276C11q4001790.45−221ribosomal protein L1177C11h6703550.53−315ribosomal protein L1378C11i9674240.44−543ribosomal protein L1279C11k8124130.51−399S19; 40S ribosomal protein S1980C11l5542860.52−26860S ribosomal protein L2181C11m14057370.52−66860S ribosomal protein L19 (RPL19)82C11n3151090.35−20640S ribosomal protein S1183C12b158480.30−110Fte-1; putative v-fos transformation effector protein; yeast mitochondrial proteinimport homolog; 40S84C12d14517870.54−664elongation factor 2 (EF2)85C12l346100.03−336clusterin (CLU); testosterone-repressed prostate message 2 (TRPM2); apolipoproteinJ; sulfated86C12m140Undefined−14activator of apoptosis harakiri (HRK); neuronal death protein 5 (DP5); BID387C13c1950.26−14SURVIVAL OF MOTOR NEURON(RSMN)88D08i6172.8311retinoid X receptor alpha (RXR alpha; RXRA); NR2B189D12c6183.0012INOSITOL TRIPHOSPHATE RECEPTOR SUBTYPE 390E01m10505.0040neurotrophin 3 precursor (NTF3); neurotrophic factor, HDNF, nerve growthfactor 2 (NGF2)91E02c1980.42−11transforming growth factor, beta 192E03k401854.63145C-type natriuretic peptide precursor (CNP; NPPC)93E04b1770.41−10thyroid stimulating hormone, beta94E07c33150.45−18c-src-kinase (CSK) & negative regulator; tyrosine-protein kinase95E08a1052492.37144extracellular signal-regulated kinase 1 (ERK1); mitogen-activated protein kinase 1(MAP kinase 1:96E08l8222.7514protein kinase C delta type (PKC-delta)97E09l36681.8932insulin receptor-related receptor-alpha (sIRR-1)98E10f3175.6714CamK II; calcium/calmodulin-dependent protein kinase brain type II beta99E10q3134.3310CamK I, calcium/calmodulin-dependent protein kinase type I + CaM-like protein kinase100E10l18422.3324Casein kinase I delta, CKId; 49-kDa isoform101E11e15291.9314cyclin-dependent kinase 4 (CDK4); cell division protein kinase 4, PSK-J3102E12g23451.9622protein phosphatase 2C isoform; Mg2+ dependent protein phosphatase beta isoform103E13i40190.48−21quanine nucleotide-bindinq protein G(I) alpha 2 subunit (GNAI2); adenylate cyclase-104E14i2686612.47393rab12, ras related GTPase105F01e10292.9019RalGDSB; GTP/GDP dissociation stimulator for a ras-related GTPase106F02a189970.51−92calcium-dependent phospholipase A2 precursor (PLA2); phosphatidylcholine 2-107F02h15795.2764phospholipase C beta 3 (PLC-beta 3)108F04e33571.732414-3-3 protein zeta/delta, PKC inhibitor protein-1, KCIP-1, mitochondrial importstimulation factor109F04k15291.931414-3-3 protein epsilon; PKC inhibitor protein-1, KCIP-1; mitochondrial importstimulation factor L110F05e8212.6313presenilin 1 (PSNL1; PSEN1; PS1); S182 protein111F05j6172.8311PDGF-associated protein112F06a591432.4284ADP-ribosylation factor 5 (ARF5)113F06j12221.8310dipeptidase (DPEP1)114F07m7294.1422granzyme M precursor (GZMM). MET-ASE; natural killer cell granular protease;RNK-MET-1115F08e111009.0989angiotensin converting enzyme (ACE; somatic; dipeptidyl carboxypeptidase I, kininase II116F08h18482.6730amonipeptidase B117F08i39922.3653kidney aminopeptidase M (APM)118F08k19814.2662metalloendopeptidase meprin beta subunit119F08l5153.0010endothelin converting enzyme120F09a3165.3313gelatinase A121F09g13272.0814cathepsin L122F09l14282.0014proteasome component C3123F12a6162.6710leukocyte common antigen-related tyrosine phosphatase (LAR)124G3112393.2527ornithine decarboxylase (ODC)125G4328711323.94845cytoplasmic beta-actin (ACTB)126G47732736140.49−371340S ribosomal protein S29 (RPS29)

[0107]

5

TABLE 2

RAT GENES (PP VS. NPP)

Fold
GenBank ID
GenBank ID

GENE
change
Human
Rat

activator of apoptosis harakiri (HRK); neuronal death
**
U76376.1
D83697

protein 5 (DP5); BID3

RET ligand 1 (RET1)
**
—
U97142

P2X purinoceptor 1; ATP receptor P2X1; purinergic
**
P51575
U14414

receptor; RP-2 protein

leukocyte common antigen precursor (LCA); CD45
**
Y00638
M10072

antigen; T200; PTPRC

amphiphysin II (AMPH2)
**
AF001383.1
Y13380

Jak3 tyrosine-protein kinase; Janus kinase 3
**
XM_038595.3
D28508

DCC; netrin receptor; immunoglobulin gene superfamily
**
M32292.1
AH002168.1

member; former tumor suppressor protein candidate

c-fgr proto-oncogene
**
AAA52762.1
X57018.1

small inducible cytokine A3 precursor (SCYA3);
**
P10147
AF119381.1

macrophage inflammatory protein 1 alpha precursor

(MIP1-alpha; MIP1A)

protein kinase C beta-If type (PKC-beta I) + protein kinase
**
X06318
P04410

C beta-II type (PKC-beta II)

E-selectin precursor; endothelial leukocyte adhesion
**
P16581
L25527

molecule 1 (ELAM-1); leukocyte-endothelial cell adhesion

molecule 2 (LECAM2); CD62E

T-cell receptor CD3 zeta subunit
**
J04132.1
L08447.1

Protein kinase C-binding protein beta15; RING-domain
**
—
U48248

containing

G1/S-specific cyclin C (CCNC)
**
AAC50825.1
D14013

maspin; protease inhibitor 5 (PI5); tumor suppressor
**
U04313.1
U58857

peptide/histidine transporter
**
—
AB000280

acetyl-CoA carboxylase (ACC); biotin carboxylase
**
X68968.1
AH002123.1

fibroblast growth factor receptor subtype 4
**
L03840.1
M91599

LCR-1; putative chemokine and HIV coreceptor homolog;
**
—
U54791

G protein-coupled receptor

tumor necrosis factor alpha precursor (TNF-alpha; TNFA);
**
AF043342.1
X66539

cachectin

CC chemokine MIP3 alpha exodus
**
—
U90447.1

luteinizing hormone, alpha
**
NM_000735.2
V01252

Ctk; non-receptor protein tyrosine kinase (batk)
**
P42679
L34542.1

RhoGAP; p122
**
—
S54293

Adenylyl cyclase type V
**
M83533.1
M96159

cathepsin S precursor (CTSS)
**
P25774
L03201.1

O-6-methylguanine-DNA methyltransferase (MGMT);
**
M31767.1
NM_012861.1

methylated-DNA-protein-cysteine methyltransferase

clusterin (CLU); testosterone-repressed prostate message
34.60
X14723
U02391.1

2 (TRPM2); apolipoprotein J; sulfated glycoprotein 2

(SGP2); dimeric acid glycoprotein (DAG)

T-cell surface glycoprotein CD5 precursor; lymphocyte
6.33
X04391.1
D10728

glycoprotein LY-1 (LYT1)

M-phase inducer phosphatase 2 (MPI2); cell division
5.67
S78187.1
D16237

control protein 25 B (CDC25B)

dopamine beta-hydroxylase
4.20
Y00096.1
L12407

SURVIVAL OF MOTOR NEURON(RSMN)
3.80
AAC50473.1
U75369

HSP84; HSP90-beta; heat shock 90kD protein
3.47
XM_055551.3
S45392

Fte-1; putative v-fos transformation effector protein; yeast
3.29
M84711.1
M84716.1

mitochondrial protein import homolog; 40S ribosomal

protein S3A; RPS3A

40S ribosomal protein S12
3.28
X53505
M18547

40S ribosomal protein S11
2.89
X06617
K03250

acetylcholinesterase, T subunit, glycolipid-anchored
2.64
M55040.1
X71089.1

carbonic anhydrase 4
2.50
NM_000717.2
I52551

thyroid stimulating hormone, beta
2.43
S70587.1
M13897.1

transforming growth factor, beta 1
2.38
M34057
NM_021578.1

prothymosin-alpha (PTMA)
2.33
AF257099.1
M20035

potassium channel, inward rectifier 11
2.33
—
D42145

ribosomal protein L12
2.28
L06505.1
X53504.1

ribosomal protein L11
2.23
X79234.1
X62146.1

c-src-kinase (CSK) & negative regulator; tyrosine-protein
2.20
X59932.1
X58631

kinase

alkaline phosphatase
2.11
AAA98616.1
S18408

guanine nucleotide-binding protein G(I) alpha 2 subunit
2.11
XM_041507.1
NM_031035.1

(GNAI2); adenylate cyclase-inhibiting G alpha protein

40S ribosomal protein S29 (RPS29)
2.03
NM_001032.2
X59051

S19; 40S ribosomal protein S19
1.97
P39019
P17074

Gax, growth-arrest-specific protein
1.95
—
Z17223.1

calcium-dependent phospholipase A2 precursor (PLA2);
1.95
M22430.1
U38376.1

phosphatidylcholine 2-acylhydrolase (PLA2-10; PLA2G5)

60S ribosomal protein L21
1.94
P46778
M27905

60S ribosomal protein L19 (RPL19)
1.91
X63527
J02650

ribosomal protein L13
1.89
P26373
X78327.1

p55cdc; cell division control protein 20
1.85
AF099644.1
AF052695.1

elongation factor 2 (EF2)
1.84
X51466
Y07504.1

I-κB (I-kappa B) alpha chain; RL/IF-1 gene product
1.79
X63594.1
AF388201.1

60S ribosomal protein L44; L36A
1.76
M15661
P10661

cytochrome c oxidase, subunit VIIIh
1.76
J04823.1
NM_012786.1

G1/S-specific cyclin D3 (CCND3)
1.75
NM_001760.2
NM_012766.1

cytochrome c oxidase, subunit IV, mitochondrial
0.59
AF017115.1
X14209

glutathione 3-transferase Yb subunit; GST subunit 4 mu
0.59
—
X04229.1

(GSTM2)

copper-zinc-containing superoxide dismutase 1 (Cu-Zn
0.58
—
NM_017050.1

SOD1)

14-3-3 protein zeta/delta; PKC inhibitor protein-1; KCIP-1;
0.58
U28964.1
L07913.1

mitochondrial import stimulation factor S1 subunit

calcium binding protein 2 (CABP2); endoplasmic reticulum
0.58
XM_012077.4
M86870

stress protein (ERP72); protein disulfide isomerase-

related protein precursor

ATPase, subunit F, vacuolar (vatf)
0.57
AF047436.1
U43175.1

proteasome component C13 precursor; macropain subunit
0.56
P28062
NM_080767.1

C13; multicatalytic endopeptidase complex subunit C13

PSMB8

vacuolar ATP synthase 16-kDa proteolipid subunit;
0.55
NM_001695.1
M62762.1

ATP6C; MVP; ATPL

dipeptidase (DPEP1)
0.55
NM_004413.1
M94056

CD4 homologue, W3/25 antigen
0.54
BC025782.
M15768.1

mitochondrial ATP synthase beta subunit precursor
0.54
NM_001686.1
M19044.1

(ATP5B)

cytochrome c oxidase subunit Vb & VIa precursor
0.54
M59250.1
X14208.1

(COX5B)

insulin receptor-related receptor-alpha (sIRR-1)
0.53
—
M90660.1

cyclin-dependent kinase 4 (CDK4); cell division protein
0.52
P11802
P35426

kinase 4; PSK-J3

14-3-3 protein epsilon; PKC inhibitor protein-1; KCIP-1;
0.52
XM_088041.1
D30739.1

mitochondrial import stimulation factor L subunit

SR13 myelin protein; peripheral myelin protein 22 (PMP-
0.52
—
M69139.1

22); CD25 protein

cytochrome P-450 4F5
0.52
—
AF288818.1

NADP+ alcohol dehydrogenase; aldehyde reductase
0.51
J04794.1
D10854.1

(ALR); 3-dG-reducing enzyme

protein phosphatase 2C isoform; Mg2+ dependent protein
0.51
—
S90449.1

phosphatase beta isoform

testis fructose-6-phosphate 2-kinase/fructose 2,6-
0.50
NM_002625.1
X15579.1

biphosphate (testis 6PF-2-K/fru-2,6-P2ase); 6-

phosphofructo-2-kinase; fructose-2,6-bisphosphatase

proteasome component C3
0.50
D00760
J02897.1

cAMP-dependent protein kinase type I-alpha regulatory
0.49
P10644
P09456

chain

cytochrome P-450 4F4
0.49
—
U39206.1

fructose-bisphosphate aldolase A (ALDOA); muscle-type
0.49
XM_043948.2
NM_012495.1

aldolase

glutathione S-transferase P subunit; GST subunit 7 pi
0.49
—
X02904.1

(GST7-7)

ATP synthase lipid-binding protein P1 precursor; ATPase
0.48
NM_005175.1
NM_017311.1

protein 9; ATP5G1

cathepsin L
0.48
M20496.1
Y00697.1

annexin IV(ANX4); lipocortin IV;36-kDa zymogen granule
0.47
XM_031596.3
NM_024155.1

membrane-associated protein (ZAP36)

mitochondrial hydroxymethylglutaryl-CoA synthase
0.47
P54868
P22791

precursor (HMG-CoA synthase); 3-hydroxy-3-

methylglutaryl-CoA synthase; HMGCS2

cytochrome B5 (CYB5)
0.45
M22865.1
D13205.1

A-raf proto-oncogene
0.44
P10398
X06942

Casein kinase I delta; CKId; 49-kDa isoform
0.43
P48730
Q06486

CD2, membrane glycoprotein, T-cell marker
0.43
M14362.1
X05111.1

kidney aminopeptidase M (APM)
0.42
XM_087746.1
M26710

rac-alpha serine/threonine kinase (RAC-PK-alpha); protein
0.42
P31749
Y15748.1

kinase B (PKB); AKT1

extracellular signal-regulated kinase 1 (ERK1); mitogen-
0.42
P27361
P21708

activated protein kinase 1 (MAP kinase 1; MAPK1);

insulin - stimulated microtubule-associated protein-2

kinase; MNK1; PRKM3; ERT2; p44-MAPK

cytochrome P450 17 (CYP17); P450C17; CYPXVII;
0.42
NM_000102.2
X69816.1

steroid 17-alpha-hydroxylase/17,20 lyase

ADP-ribosylation factor 5 (ARF5)
0.41
NM_001662.
NM_024149.1

rab12, ras related GTPase
0.41
—
M83676.

microsomal glutathione S-transferase (GST12; MGST1)
0.40
XM_048886.3
J03752

apolipoprotein A-I precursor (APO-AI)
0.38
X02162
M00001

presenilin 1 (PSNL1; PSEN1; PS1); S182 protein
0.38
XM_007441.1
D82363

amonipeptidase B
0.38
|XM_087242.1
U61696

leukocyte common antigen-related tyrosine phosphatase
0.38
—
U00477.1

(LAR)

NADPH-cytochrome P450 reductase (CPR); POR
0.37
S90469
NM_031576.1

protein kinase C delta type (PKC-delta)
0.36
NM_006254.1
M18330

proteasome delta subunit precursor; macropain delta;
0.36
X61971.1
NM_057099.1

multicatalytic endopeptidase complex delta; proteasome

subunit Y; proteasome subunit 5; PSMB6

sodium channel SCNB2, beta 2 subunit, brain
0.36
AAC05208.1
NM_012877.

retinoid X receptor alpha (RXR alpha; RXRA); NR2B1
0.35
XM_088424.1
NM_012805.1

PDGF-associated protein
0.35
U41745.1
U41744.1

Na+/K+ ATPase alpha 1 subunit
0.35
AAA51801.1
M28647

RalGDSB; GTP/GDP dissociation stimulator for a ras-
0.34
—
NM_019250.1

related GTPase

interferon regulatory factor 1 (IRF1)
0.33
XM_034862.1
M34253

LIM domain protein CLP36, homologous to rat RIL
0.33
AJ310549.1
U23769.1

adenylate kinase 3
0.33
XM_016642.3
NM_13218.1

INOSITOL TRIPHOSPHATE RECEPTOR SUBTYPE 3
0.33
—
L06096.1

endothelin converting enzyme
0.33
Z35307.1
D29683

fibroblast ADP/ATP carrier protein; ADP/ATP translocase
0.33
J02683
D12771

2; adenine nucleotide translocator 2 (ANT2)

cytochrome c oxidase, subunit Va, mitochondrial
0.31
M22760.1
X15030

fatty acid-binding protein (intestinal; I-FABP; FABPI)
0.31
M18079
M18080.1

ornithine decarboxylase (ODC)
0.31
X16277
D11372.1|

antigen peptide transporter 1
0.30
X57522
P36370

lipocortin 2
0.29
D00017.1
S73557

signal transducer CD24 precursor; heat stable antigen
0.28
P25063
U49062

(HSA); nectadrin

cytoplasmic beta-actin (ACTB)
0.25
M10277.1
V01217

fructose-bisphosphate aldolase B (ALDOB); liver-type
0.24
XM_042788.1
M10149

aldolase

granzyme M precursor (GZMM); MET-ASE; natural killer
0.24
NM_005317.2
Q03238

cell granular protease; RNK-MET-1

scavenger receptor class B type I
0.24
—
AB002151.1

glutamyl aminopeptidase A
0.24
XM_003595.2
S73583

metalloendopeptidase meprin beta subunit
0.23
—
M88601.1

glutathione synthetase (GSH synthetase; GSH-S; GSS);
0.23
U34683.1
L38615.1

glutathione synthase

cytochrome oxidase, subunit I, Sertoli cells
0.23
S79304
S79304

CamK I; calcium/calmodulin-dependent protein kinase
0.23
Q14012
L24907

type I + CaM-like protein kinase

C-type natriuretic peptide precursor (CNP; NPPC)
0.22
NM_024409.1
D90219

neurotrophin 3 precursor (NTF3); neurotrophic factor;
0.20
M37763.1
M34643

HDNF; nerve growth factor 2 (NGF2)

phospholipase C beta 3 (PLC-beta 3)
0.19
NM_000932.1
M99567

ATP synthase, subunit c, P2 gene
0.19
D13119.1
D13124

gelatinase A
0.19
NM_004530.1
U65656

glutathione S-transferase Ya subunit (GST YA); ligandin
0.18
NM_000852.2
K01932

subunit 1 alpha

creatine kinase, ubiquitous, mitochondrial
0.18
XM_016524.4
X59737

fatty acid-binding protein (liver; L-FABP); Z-protein;
0.18
NM_001443.1
M35991

squalene- & sterol-carrier protein (SCP); P14

cytochrome P-450 4F1, hepatic tumour
0.18
—
NM_019623.1

CamK II; calcium/calmodulin-dependent protein kinase
0.18
NM_001220.1
M16112

brain type II beta

sodium-glucose cotransporter 1
0.16
P13866
U03120

fructose (glucose) transporter
0.16
AAB60641
D13871.1

urate transporter/channel
0.15
—
U67958

sodium/potassium-transporting ATPase beta 1 subunit
0.13
NM_001677.1
NM_013113.1

(ATP1B1)

fatty acid amide hydrolase
0.12
U82535.1
U72497

proton-coupled dipeptide cotransporter
0.11
—
D50306.1

angiotensin converting enzyme (ACE; somatic; dipeptidyl
0.11
NM_000789.1
NM_012544.1

carboxypeptidase I; kininase II

apolipoprotein A-IV precursor (APO-AIV)
0.10
XM_052144.2
P02651

ErbB3 EGF receptor-related proto-oncogene; HER3
0.08
M29366.1
NM_017218.2

Jun-B; c-jun related TF,
**
M29039.1
X54686

S-myc proto-oncogene; myc related,
**

M29069

C-est-I proto-oncogene; p54.
5
AF193068.1
X55787.1

Jun-D; c-jun related TF,
1.79
X56681.1
D26307(mouse)

NF-kappaβ Tf p105 subunit,
1.67
P19838
L26267.1

Nm23-M2; nucleoside diphosphate kinase B;
1.47

X68193.1

metastasis reducing protein,

(mouse)

STAT 3 —signal transducer and activator of
1.16
NM_003150.1
NM_012747.1

transcription 3,

CREB active TF,
1

M34356.1

New england deaconess TF,
1

U09229

Lim-2; embryonic motor neuron topographic
1

L35572

organizer; homeobox protein LIM-2, and

NDK-B; nucleoside diphosphate kinase B;
0.81

U29200.1

metastasis reducing protein,

C-jun proto-oncogene; TF AP-1; RJG-9,
0.5
J04111.1
X17215.1

Symbols indicating fold changes in Table 2:

** expressed in PP but not NPP, or in co-culture but not in Caco-2 cells.

* expressed in co-culture but not in Caco-2 cells (only repeated once).

— expressed in Caco-2 but not in co-culture.

Example 5

ATLAS Array Data on Co-Culture of Human Caco-2 Cells and Raji B-Cells

[0108] In order to facilitate the routine study of M cell biology, there was a desire to establish a suitable and representative in-vitro model. In the work carried out by Kernéis et al. (Kerneis S, Caliot E, Stubbe H, Bogdanova A, Kraehenbuhl J, Pringault E (2000). Molecular studies of the intestinal mucosal barrier physiopathology using co-cultures of epithelial and immune cells: a technical update. Microbes Infect Jul. 2, 2000 (9):1119-24), it was reported that Peyer's patch lymphocytes co-cultured with Caco-2 cells trigger the phenotypic conversion of enterocytes into cells that express morphological and functional M-cell properties. This work was further developed by Gullberg et al. (Gullberg E, Leonard M, Karlsson J, Hopkins A M, Brayden D, Baird A W, Artursson P. Expression of specific markers and particle transport in a new human intestinal M-cell model. Biochem Biophys Res Commun Dec. 29, 2000; 279(3): 808-13) to create a simplified in vitro model of the human M-cell. Co-cultures of physically separated human intestinal epithelial Caco-2 cells and B-cell lymphoma Raji cells were established. The co-cultures were characterized under the criteria of morphology, integrity, expression of M-cell markers and cell adhesion molecules (CAMs), and altered particle transport. Using this construct, the epithelial cells were transformed to cells with an M-cell-like morphology and had altered expression of potential human M-cell markers (alkaline phosphatase down-regulation and Sialyl Lewis A antigen up-regulation). The expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule was altered, and there was an increased binding of lectins wheat germ agglutinin and peanut agglutinin with a 40-fold increase in microparticle transport. The particle transport was size-dependent and could be inhibited at 4° C. or by replacing the Raji B-cells with Jurkat T-cells. Thus the comparison of RNA isolated from co-cultured Caco2 cells to that isolated from normal Caco2 cells was designed to simulate a comparison of M cell RNA to normal gut enterocyte RNA.

Isolation of Total RNA from Co-Cultured Caco-2 Cells

[0109] Caco-2 Cell Culture

[0110] Caco-2 cells were cultured in Dulbecco's Modified Eagles Medium (DMEM), 4.5 g/L glucose supplemented with 1% Mem, 10% FCS and 1% penicillin/streptomycin a t 37° C. and 5% CO2 in 95% relative humidity. Cells were grown and expended in Falcon culture flasks and passaged once they attained 100% confluence. Caco-2 cells were seeded on Transwell Clear filters (Costar, 12 mm diameter, 3.0 μm pore size)) at a density of 5×105 cells/cm2 and incubated in a 12 well culture plate with a medium change every second day. 1.0 ml was added to the basolateral side and apical sides.

[0111] Raji Cell Culture

[0112] Raji B-lymphoma cells were cultured in RPMI 1640 Medium, with 1% (v/v) non-essential amino-acids, 10% FCS and 1% penicillin/streptomycin, 1% L-glutamine at 37° C. and 5% CO2 in 95% relative humidity. Cells were grown in suspension in Falcon tissue culture flasks and passaged by dilution every 5-7 days.

[0113] Co-Culture: Day 14 (Treating with Raji B-Cells)

[0114] After 14 days of culturing Caco-2 monolayers, 15-20 ml of Raji cells were removed from the T75 flask and placed in a 20 ml universal. The cells were centrifuged at 1000 rpm for 3 min. Cells were re-suspended at a concentration of 1×106 cells/ml. 1 ml of fresh complete DMEM was added to the apical and basolateral sides of the Caco-2 monolayer filters. 0.5 ml of 1×106 Raji cells/ml cells was added to the basolateral side of the filters. For control filters (non co-culture) 0.5 ml of Raji medium only was added to the basolateral side.

[0115] Isolation of Total RNA from Co-Cultured Caco-2 Cells

[0116] After 4 days of co-culture the filters were rinsed in PBS. 0.5 ml of PBS was added to the apical side of each filter and the Caco-2 cells were scraped off the filter surface into suspension in the PBS. The cells from all the co-cultured Caco-2 filters were pooled, centrifuged at 1000 rpm for 3 min, the supernatant PBS was removed and the pellet was used for RNA extraction.

[0117] Analysis of mRNA Expression

[0118] Total cellular RNA was extracted using an acid guanidinium thiocyanate-phenol-chloroform method. RNA's integrity was confirmed by gel electrophoresis and ethidium bromide staining. mRNA was reverse transcribed in the presence of P32 dATP, and the transcribed cDNA was purified by chromatography before being hybridized over night to the array membrane. Membranes were exposed to x-ray film using an intensifying screen for 3 days and the mRNA expression levels were analyzed by scanning the films with a densitometer. Expression levels were normalized relative to internal standards, and relative increases in mRNA levels in co-cultured cells versus monoculture controls were calculated. Two hybridization experiments were performed using mRNA from two separate cell harvests. Results from the two experiments were pooled, and a summary of the findings was tabulated in Tables 3(a)-3(f). The identified genes are from the following groups: oncogenes, tumor suppressor genes, genes involved in the cell cycle, ion channels and transport, stress response genes, modulators and effectors, genes involved in intracellular transduction, genes linked to apoptosis, DNA synthesis, repair & recombination, transcription factors, DNA binding proteins, receptors, cell surface antigens, genes involved in cell adhesion, growth factors, cytokines, chemokines and hormones.

[0119] In Table 3, genes which were found to be exclusively over-expressed in the co-culture and not in the control Caco-2 monolayer are represented by **. A single asterisk represents genes that also were expressed in the co-culture and not in the control Caco-2 monolayer. However, these particular genes have been distinguished from the genes labeled with two asterisks as they were not expressed in both hybridization experiments performed, and will require confirmation in the future by PCR so as to rule out false positives/negatives. Genes not expressed in the co-culture but expressed in the Caco-2 monolayer controls are indicated by a minus symbol, “−”.

6TABLE 3 aOncogenes, Tumor Suppressors, Cell Cycle RegulatorsGeneFold changeGenBank IDMyeloid cell nuclear differentiation*M81750antigen (MNDA)G1/S-specific cyclin D1 (CCND1);*X59798cyclin parathyroid adenomatosis 1(PRAD1); bcl-1 oncogenecyclin-dependent kinase 4 inhibitor 2*L27211.1(CDK4I; CDKN2); p16-INK4; multipletumor suppressor 1 (MTS1)cyclin-dependent kinase inhibitor 1C*U22398(CDKN1C); p57-KIP2ezrin; cytovillin 2; villin 2 (VIL2)1.69X51521proto-oncogene tyrosine-protein1.55L04143.1kinase kit; c-kit; mast/stem cellgrowth factor receptorprecursor(SCFR); CD117 antigenproliferating cell nucleolar anti-1.52M32110gen P120; NOL1jun proto-oncogene; avian sarcoma1.47J04111virus 17 oncogene homolog;transcription factor AP-1C-src proto-oncogene (SRC1)1.35X59932CDC-like kinase 3 (CLK3)1.35L29220cell division cycle protein 251.34M91815.1nucleotide exchange factor (CDC25)prothymosin alpha (PROT-alpha; PTMA)1.32M2670840S ribosomal protein S19 (RPS19)1.31M81757avian myelocytomatosis viral1.30V00568oncogene homolog (MYC)CDC-like kinase 1 (CLK1)1.27L29219.1cyclin-dependent kinase 4 inhibitor0.69U49399.12D (CDKN2D); p19-INK4Dvascular endothelial growth factor0.62XM_039993.2receptor 1 (VEGFR1); tyrosine-protein kinase receptor flt +soluble VEGFR; tyrosine-proteinkinase receptor SFLTneogenin—U61262.1webB2 receptor protein-tyrosine—M11730.1kinase; neu proto-oncogene; c-erbB2 +HER2 receptorN-ras; transforming p21 protein—AAA60255

[0120]

7

TABLE 3 b

Ion Channels, Modulators, Effectors

Gene
Fold change
GenBank ID

extracellular signal-regulated
**
X14798.1

kinase 3 (ERK3); mitogen-activated

protein kinase 6 (MAP kinase 6;

MAPK6; PRKM6); p97-MAPK

40-kDa heat-shock protein 1 (HSP40);
**
D49547

DNAJ protein homolog 1 (HDJ1; DNAJ1)

70-kDa heat shock protein 1
**
M11717

(HSP70.1; HSPA1)

glutaredoxin
**
X76648

tyrosine kinase receptor tie-1
*
AAB84296

precursor

ras-related protein RAB3B
*
NM_002867.1

macMARCKS; MARCKS-related protein
*
P49006|

(MRP); MLP

mitogen-activated protein kinase 3
*
P27361

(MAPK3; PRKM3); MAPK1; extra-

cellular signal-regulated kinase

1 (ERK); microtubule-associated

protein 2 kinase, insulin-

stimulated MAP2kinase

mitgoen-activated protein kinase 9
*
NM_002752.1

(MAP kinase 9; MAPK9; PRKM9); c-jun

N-terminal kinase 2 (JNK2); JNK55

60-kDa heat shock protein (HSP60);
*
M22382.1

HSPD1; 60-kDa chaperonin;

mitochondrial matrix protein

P1 precursor; p60 lymphocyte

protein; HUCHA60; GROEL

serine kinase
2.24
U09564.1

transferrin receptor (TFRC); CD71
1.80
M11507.1

antigen

Neurotrophic tyrosine kinase
1.63
U55017.1

receptor-related 3: TKT percursor

phospholipase C (PLCL)
1.62
X14034.

cAMP-response element binding
1.59
M27691.1|

protein (CREB)

ephrin type-A receptor 1 precursor;
1.55
M18391

tyrosine-protein kinase receptor eph

27-kDa heat-shock protein (HSP27);
1.42
X54079.1

stress-responsive protein 27

(SRP27); estrogen-regulated 24-kDa

protein; HSPB1

tyrosine kinase tnk1
1.42
XM_012654.3

ras-related protein RAB3A
1.38
XM_054457.2

janus kinase 3 (JAK3); leukocyte
1.33
XM_038595.3

janus kinase (L-JAK)

dual-specificity mitogen-activated
1.29
NM_002755.2

protein kinase kinase 1 (MAP kinase

kinase 1; MAPKK 1; MKK1);

extracellular signal-regulated

kinase 1; ERK activator kinase 1

calcium/calmodulin-dependent protein
1.27
NM_001744.1

kinase type IV catalytic subunit

(CAMK IV); CAM kinase-GR

ras-related protein RAB5A
0.75
XM_053461.2

colon carcinoma kinase 4 precursor
0.68
U33635.1

(CCK4) + transmembrane receptor

PTK7

epithelial discoidin domain receptor
0.63
XM_004559.5

1 precursor (EDDR1; DDR1); cell

adhesion kinase (CAK); TRKE;

RTK6; protein tyrosine kinase 3A

(PTK3A); neuroepithelial tyrosine

kinase (NEP)

ras-related protein RAB6
0.27
M28212.1

cAMP-dependent protein kinase type I
0.23
M65066.1

beta regulatory subunit (PRKAR1B)

tyrosine-protein kinase ack
—
CAC15525

T-lymphocyte maturation-associated
—
P21145

protein MAL

orphan hormone nuclear receptor
—
U04897.1

LIM domain kinase 1 (LIMK-1)
—
P53667

protein kinase C alpha polypeptide
—
NM_002737.1

(PKC-alpha; PKCA)

dual specificity mitogen-activated
—
P46734

protein kinase kinase 3 (MAP kinase

kinase 3; MAPKK3; MKK3); ERK

activator kinase 3; MAPK/ERK

kinase 3 (MEK3)

Yamaguchi sarcoma viral-related
—
M16038.1

oncogene homolog; tyrosine-protein

kinase lyn

protein-tyrosine phosphatase 1E
—
U12128.1

[0121]

8

TABLE 3.c

Apoptosis, DNA Synthesis, Repair & Recombination

Gene
Fold change
GenBank ID

ubiquitin-conjugating enzyme E2 17-
**
NM_003336.1

kDa (UBE2A); ubiquitin-protein

ligase; ubiquitin carrier protein,

HR6A

growth arrest & DNA-damage-inducible
**
S40706.1

protein 153 (GADD153); DNA-damage-

inducible transcript 3 (DDIT3); C/EBP

homologous protein (CHOP)

growth factor receptor-bound protein
*
M96995.1

2 (GRB2); ASH protein

glutathione S-transferase A1 (GTH1;
*
M21758.1

GSTA1); HA subunit 1; GST-epsilon

cytoplasmic dynein light chain 1
*
U32944.1

(HDLC1); protein inihibitor of

neuronal nitric oxide synthase (PIN)

xeroderma pidmentosum group G
*
NM_021141.2

complementing protein (XPG); X-ray

repair-complementing defective repair

in Chinese hamster cells 5 (XRCC5)

xeroderma pigmentosum group D
*
AF035587.1

complementing protein (XPD); X-ray

repair-complementing defective repair

in Chinese hamster cells 2 (XRCC2)

RAD23 homolog A (RAD23A; hHR23A)
*
NM_005053.1

ataxia telangiectasia (ATM)
*
AAB38309

apoptosis regulator bcl-x
1.60
Z23115.1

caspase 9 percursor (CASP9); ICE-like
1.42
AB020979.1

apoptotic protease 6 (ICE-LAP6);

apoptotic protease MCH6;

apoptotic protease activating factor

3 (APAF3)

CD40 receptor-associated factor 1
1.39
U21092.1

(CRAF1)

SL cytokine precursor; FMS-related
1.35
NM_001459.1

tyrosine kinase 3 ligand (FLT3

ligand; FLT3LG)

cytochrome P450 reductase
1.33
AAD45961.1

X-ray repair complementing defective
1.25
M36089

repair in

Chinese hamster cells 1 (XRCC1)

Ku (p70/p80) subunit; ATP-dependent
0.74
X57500.1

DNA helicase II 86-kDa subunit; lupus

ku autoantigen protein; thyroid-lupus

autoantigen (TLAA); CTC box

binding factor 85-kDa subunit (CTCBF;

CTC85); nuclear factor IV

caspace 10 precursor (CASP10); ICE-
0.45
Q92851

LIKE apoptotic protease 4 (ICE-LAP4);

apoptotic protease MCH4; fas-

associated death domain

protein; interleukin 1 beta-

converting enzyme 2 (FLICE2);

inhibitor of apoptosis protein 2
—
Q13490

(HIAP2; IAP2) + IAP homolog B;

TNFR2-TRAF signaling complex

protein 2; MIHB

recA-like protein HsRad51; DNA repair
—
BAA02962.1

protein RAD51 homolog

DNA damage repair & recombination
—
B56529

protein 52 (RAD52)

DNA ligase III (LIG3); polydeoxyribo-
—
CAA59230.1

nucleotide synthase

[0122]

9

TABLE 3 d

Transcription Factors, DNA Binding Proteins

Gene
Fold change
GenBank ID

transcriptional activator hSNF2-alpha
**
D26155.1|

early growth response protein 1
2.71
M62829.1

(EGR1); transcription factor ETR103;

KROX24; zinc finger protein 225

(ZNF225); AT225

homeobox A1 protein (HOXA1); HOX1F
2.17
U10421.1

transcription factor NF-ATc
1.67
U08015.1

R kappa B DNA-binding protein
1.66
U08191.1

transcription initiation factor IID
1.57
M55654

31-kDa subunit (TFIID); TATA-box-

binding protein-associated factor RNA

polymerase II G 32-kDa subunit

(TAFII32; TAF2G); TAFII31

homeobox protein hLim1; LHX1
1.51
NM_005568.1

helix-loop-helix protein HLH 1R21;
1.49
X69111.1

DNA-binding protein inhibitor Id-3;

HEIR-1

guanine nucleotide-binding protein
1.46
NP_000507.1

G-s alpha subunit (GNAS); adenylate

cyclase-stimulating G alpha protein

CCAAT-binding transcription factor
1.45
AAA40889.1

subunit B (CBF-B); NF-Y protein sub-

unit A (NF-YA); Hap2; CAAT-box DNA-

binding protein subunit A

transcription factor LSF
1.37
B53771

homeobox 2.1 protein (HOX2A); HOXB5;
1.35
M92299.1

HU1; HHO.C10

endothelial transcription factor
1.34
M68891.1

GATA2

transcription factor Sp1 (TSFP1)
1.30
XM_028606.2

transcription factor ZFM1
0.62
G02919

zinc finger protein 161 (ZNFI61);
0.26
NP_009077.1

putative transcription activator DB1

stem cell protein (SCL); T-cell
—
AAA36598.1

leukemia/lymphoma-5 protein (TCL5);

T-cell acute lymphocytic leukemia-1

protein (TAL1)

neural retina-specific leucine zipper
—
NP_006168

protein (NRL)

MSX-1 homeobox protein; HOX7
—
P28360

basic transcription factor 62-kDa
—
AAA58399.1

subunit (BTF2)

paired box homeotic protein (PAX8)
—
BAB59039.1

isoforms 8A/8B + isoforms 8C/8D

brain-specific homeobox/POU domain
—
AAA65605.1

protein 3A (brn-3A); RDC-1; octamer

binding transcription factor 1 (OTF1)

transcription factor E2-alpha (E2A);
—
AAA61146.1

immunoglobulin enhancer binding

factor E12; transcription factor-3

(TCF3)

transcriptional enhancer factor
—
P28347

(TEFI); protein GT-IIC; transcription

factor 13 (TCF13)

thioredoxin perodxidase 2 (TDPX2);
—
Q06830

thioredoxin-dependent peroxide

reductase 2; proliferation-

associated gene (PAG); natural killer

cell enhancing factor A (NKEFA)

[0123]

10

TABLE 3 e

Receptors, Cell Surface Antigens, Cell Adhesion

Gene
Fold chance
GenBank ID

interleukin-2 receptor gamma subunit
*
AAA59145.1

(IL-2R gamma; IL2RG); cytokine

receptor common gamma chain

precursor; p64

interferon gamma receptor (IFNGR)
*
NM_000416.1|[

interleukin-1 receptor type I
*
M27492.1

precursor (IL-1R1); IL-1R-aplha; p80;

CDW121A antigen

neural-cadherin precursor (N-
*
L34059

cadherin; NCAD); cadherin 2 (CDH2)

neural cell adhesion molecule L1
*
M77640

precursor (N-CAM L1); MIC5

integrin alpha 3 (ITGA3); galacto-
*
M59911.1

protein B3 (GAPB3); very late antigen

3 alpha subunit (VLA3 alpha); CD49C

antigen

leukocyte adhesion glycoprotein p150,
*
M81695.1

95 alpha subunit precursor; leukocyte

adhesion receptor p150, 95; CD11C

antigen; leu-M5; integrin alpha X

(ITGAX)

integrin beta 4 (ITGB4); CD104
*
X51841.1

antigen

CD44 antigen precursor (CD44);
1.51
XP_030326.1

phagocytic glycoprotein I (PGP1);

HUTCH I; extracellular matrix

receptor III (ECMR III); gp90

lymphocyte homing/adhesion receptor

(LHR); hermes antigen; hyaluronate

receptor; heparan sulfate

proteoglycan; epican

glutamate receptor subunit epsilon 3
1.44
NP_000826.1

precursor (GRIN2C); N-methyl D-

aspartate receptor subtype 2C

(NMDAR2C; NR2C)

CD27L antigen receptor precursor;
0.7
P26842

tumor necrosis factor receptor

superfamily member 7 (TNFRSF7); T14

integrin alpha L (ITGAL); leukocyte
0.45
P20701

adhesion glycoprotein alpha subunit

precursor; leukocyte function-

associated molecule 1 alpha chain

(LFAI); CD11A antigen

interleukin 2 receptor alpha subunit
0.41
P01589

precursor (IL-2 receptor alpha

subunit; IL2RA); TAC antigen; CD25

antigen

CDW40 antigen; CD40L receptor
0.35
CAA43045.1

precursor; nerve growth factor

receptor-related B-lymphocyte

activation molecule

granulocyte colony stimulating factor
—
Q99062

receptor precursor (GCSF-R); CD114

antigen

low-affinity nerve growth factor
—
AAB59544.1

receptor (NGF receptor; NGFR); GP80-

LNGFR

neuromedin B receptor (NMBR);
—
NP_002502.1

neuromedin-B-preferring bombesin

receptor

granulocyte-macrophage colony-
—
Q00941

stimulating factor receptor alpha

(GM-CSFR-alpha); CSW116 antigen

platelet membrane glycoprotein IIIA
—
P05106

precursor (GP3A); integrin beta 3

(ITGB3); CD61 antigen

integrin alpha 7B precursor (IGA7B)
—
CAA52348.1

[0124]

11

TABLE 3 f

Growth Factors, Cytokines, Hormones

Gene
Fold change
GenBank ID

Interleukin-10 precursor (IL-10);
**
M57627

cytokine synthesis inhibitory factor

(CSIF)

Granulocyte-macrophage colony
*
AAA52578.1

stimulaitng factor (GM-CSF); CSF2

FMLP-related receptor I (FMLPRII);
*
AAA58482.1

RMLP-related receptor I (RMLPRI)

Glia maturation factor beta
*
P17774

(GMF-beta)

Hepatoma-derived growth factor (HDGF)
*
P51858

Macrophage inflammatory protein 1
*
P10147

alpha precursor (MIP1-alpha);

tonsillar lymphocyte LD78 alpha

protein; G0S19-1 protein; PAT 464.2;

SIS-beta; small inducible cytokine

A3 (SCYA3)

Monocyte chemotactic protein 1
*
P13500

precursor (MCP1); monocyte

chemotactic and activating factor

(MCAF); monocyte secretory protein

JE; monocyte chemoattractant protein

1; HC11; small inducible cytokine A2

(SYCA2).

Oncostatin M (OSM)
*
NP_065391.1

Renin-binding protein (RENBP; RNBP)

XP_013053.3

Calgranulin B (CAGB); migration
1.49
B31848

inhibitory factor-related protein 14

(MRP14); leukocyte L1 complex heavy

chain; S100 calcium binding protein

A9 (S100A9)

Placenta growth factors 1 + 2
1.42
CAA38698.1

(PLGF1 + PLGF2)

Vascular endothelial growth factor
1.42
AAA35789.1

precursor (VEGF); vascular

permeability factor (VPF)

Hepatocyte growth factor activator
1.40
BAA74450.1

(HGF activator)

Follistatin-related protein precursor
1.34
AAA66062.1

Hepatocyte growth factor-like protein;
1.29
AAA59872.1

macrophage stimulating protein (MSP)

Interferon gamma precursor (IFN-
1.29
P01579

gamma, IFNG); immune interferon

WSL protein + TRAMP + Apo-3 +
0.69
AAB41432.1

death domain receptor 3 (DDR3)

Neurotrophin-4 (NT4)
0.68
AAA60154.1

Interleukin-13 precursor (IL-13);
0.39
P35225

NC30

Small inducible cytokine A5 (SYCA5);
0.38
XP_035842.1

regulated on activation normal T-

cell-expressed & secreted

protein precursor (RANTES); SIS delta

Estrogen sulfotransferase (STE; EST1)
—
CAA72079.1

Keratinocyte growth factor (KGF);
—
AAA63210.1

fibroblast growth factor 7 (FGF7)

Endothelial-monocyte activiting
—
AAA62202.1

polypeptide II (EMAP II)

Leukemia inhibitory factor precursor
—
B36282

(LIF); differentiation-stimulating

factor (D factor); melanoma derived

LPL inhibitor (MLPLI); HILDA

Acidic fibroblast growth factor
—
AAA51672.1

(AFGF) + heparin-binding growth

factor 1 precursor (HBGF-1) +

beta-endothelial cell growth

factor (ECGF-beta)

Insulin-like growth factor-binding
—
P17936

protein 3 precursor (IGF-binding

protein 3; IGFBP3; IBP3)

Symbols (Fold Changes)

**Expressed in PP but not NPP, or in Co-culture but not Caco2.

*Expressed in Co-culture but no Caco2 (only repeated once)

—Expressed in Caco2 but not in co-culture.

Immunity

[0125] The events of the cell cycle occur under normal circumstances in a fixed sequence. Traditionally, the cycle is divided into two stages: cell division and the interphase. Cell division or mitosis is followed by cytokinesis and together they constitute the ‘M phase’ of the cell cycle. The interphase is divided up into the S, G1 and G2 phases. Briefly, during the S phase, DNA is replicated in preparation for mitosis, while the intermediate G phases are transitional periods involved in protein synthesis and cell growth. Activation of regulatory genes that control and maintain a cell's proliferative state by intracellular signals (discussed below) stimulates proliferation of the cell and initiates cell growth. A number of genes involved in these processes were differentially expressed in the co-culture model (as estimated by relative mRNA abundance) and discussed below.

[0126] The epithelial cells of the gut play an important part of the innate and specific immunity. IEC's are considered to be in a continuous controlled state of “physiological” inflammation and active processes continually take place to ensure that the tone of immunosuppression is maintained (Mayer, 2000). These unique regulators appear to control the mucosal immune system's condition. These distinct factors govern the immune response, whether it's immune suppression/tolerance, inflammation or a systemic immune response. A clearer understanding of the immunoregulatory features involved in mucosal immunity is clearly desirable and may lead to new approaches in disease and drug therapy. Genes detected in the co-culture model that may be related to or are involved in immune function in GALT are discussed below.

[0127] The gamma subunit if IL-2 receptor plays a pivotal role in formation of the full-fledged IL-2 receptor (Di Santo et al., 1995). In an interesting study where infant rats were studied from pre- to post weaned life Masjedi et al. (1999) assessed alterations in expression and phenotype of cells in the gut-associated lymphoid tissue. At an age when the immune system is believed to be immature and functionally naive they discovered interleukin-2 receptor (IL-2R) expression peaked approximately four-fold at midweaning in Peyer's patches, compared with adult animals (day 70) suggesting that IL-2R expression is an adaptation to the host's environment. In a similar way, the presence of IL-2R specific for cells in the co-culture could be a direct result of the environment. The common gamma c chain of the interleukin 2 receptor, gamma is also a component of the receptors for IL-4, 1 L-7, and IL-9 and plays a critical role in lymphoid development through its participation in the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15 (Di Santo et al., 1995)

[0128] Interferon-γ (IFN-γ) exhibits various properties including antigrowth activity in neoplastic and normal cells, and regulatory roles in immune responses (Tsuji et al., 1998). Kjerrulf et al. (1997) found that in IFN-γ receptor knockout mice (IFN-γR−/−) reduced mucosal antibody responses and decreased Th1 and Th2 activity after oral immunization. The presence of IFN-γ receptor in the M cell co-culture model could possibly augment a cross-regulation between the two Th subsets in the gut mucosa. It is noteworthy that the ligand, IFN-γ, mRNA was increased in the co-culture that was supported further by the significant secretion of IFN-γ from co-culture monolayers.

[0129] The C-C chemokines macrophage inflammatory protein 1 (MIPLα) and monocyte chemotactic protein (MCP1) are synthesized and expressed by epithelial cells (Vainer et al., 1998; Kolios et al., 1999). The purpose of these chemokines expression in the co-culture model could be to function not only in leukocyte migration, but also as adhesins in the interaction between leukocytes and colonic epithelium. However, another C-C chemokine, RANTES, mRNA was observed to be reduced in the co-culture. The reasons for this are unclear. Perhaps, the chemoaffractant activities of other chemokines such as IL-8, MIP1α and MCP1 are sufficient for the M cell and in the absence of T cells the need for RANTES is not required.

[0130] From a gene delivery perspective, a higher capacity for translation and protein synthesis in PP tissue indicates that PP tissue is a preferred tissue to which to deliver genes coding for DNA vaccines or antigens. Thus the proposed higher translational capacity of PP tissue has implications for gene delivery especially DNA vaccine delivery and correspondingly antigen expression and local presentation to the mucosal immune system in the gastrointestinal tract. The TF coding genes may be important in priming M cells or precursor cells to M cells to adopt M cell phenotype and/or to facilitate priming of M cells to give a better immune cell outcome.

[0131] M cell receptors identified in Table 3(e) above are of particular interest in that they can be used for vaccine and delivery.

[0132] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of an IL-2 receptor, a gamma c chain of an IL-2 receptor, intereron-γ, and a C—C chemokine.

Proliferation and Growth

[0133] Cyclin DI is a protein involved in regulation of the cell cycle. Over-expression of the protein is associated with abnormal growth or neoplasia. This protein is positively induced by the p42/p44 MAP kinases (Lavoie et al., 1996). It would be interesting if the neoplasia seen in M cells resulted from activation of this protein considering the coincidental induction of the p44 MAP kinase (ERK1) below. The reduction in cyclin-dependent kinase 4 inhibitor 2D (CDKN2D) mRNA that normally inhibits cell cycle progression (Guan et al., 1996) would insinuate a similar function in the proliferation of these ‘M cells.’

[0134] In contrast, the induction of cell cycle inhibitors such as cyclin-dependent kinase inhibitor (CDKI) and cyclin-dependent kinase 4 inhibitor (CDK4J) would appear to be working to counterbalance proliferative stimuli present in the M cell.

[0135] PLC-L (phospholipase C-deleted in lung carcinoma) is a putative tumor suppressor gene. It is believed that irregular (in fact deletion) expression of the PLC-L gene contributes to the growth of human lung carcinoma (Kohno et al., 1995). It is possible then that its upregulation in the M cell model is acting as a negative regulator of growth in the cells, counterbalancing the many proliferative signals present.

[0136] Growth factor receptor-bound protein 2, GRB2, involved in growth factor control of ras signalling (Lowenstein et al., 1992).

[0137] The intracellular signaling pathways responsible for cell cycle arrest and establishment of differentiated cells along the gut axis remain largely unknown particularly in the case for the development of M cells and the FAE. ERK3/MAPK6 is expressed solely in the co-culture. Extracellular signal-regulated kinases-1 (ERK1) also known as the p44 mitogen-activated protein (MAP) kinase (p44mapk) is also induced specifically in the co-culture model. ERK1 and ERK3 are proline-directed serine/threonine kinases that are activated in response to a variety of extracellular signals, including growth factors, hormones and, neurotransmitters. These MAP kinases are key molecules involved in intracellular signal transduction, and are key regulators of cell proliferation in mammalian cells (Davis, 1995). Results indicate that elevated p42/p44 MAPK activities stimulate cell proliferation of intestinal cells, whereas low sustained levels of MAPK activities have correlated with cell cycle arrest and an increased expression of sucrase isomaltase (Aliaga et al., 1999). It is tempting to speculate that the presence of ERK3 together with the other MAP kinases apart from their proliferative effects are in part responsible for a reduction in sucrase isomaltase, a characteristic effect in M cells.

[0138] Lying upstream in the ERK signal cascade the tyrosine/threonine protein kinase, MAPK kinase (MAPKK1) is implicated in the regulation of cell growth and differentiation through the activation of ERK. In addition it is interesting to note that MAPKK3 was deleted in the co-culture cells. MAPKK3 phosphorylates and activates p38 MAP kinase alpha and gamma isoforms (Enslen et al., 1998). The induction of the MAPKK1 gene along with serine kinase coincides with the induction of ERK1, highlighting the ERK cascade as an important signalling cascade in M cell maintenance. It is interesting to note that ERK activation is responsible for terminal differentiation of components of the crypt-villus. (Taupin and Podolsky, 1999)

[0139] However, glia maturation factor-β (GMF-β) is potentially offsetting the ERK cascade effects. It is known to inhibit MAP kinases particularly ERK1 and ERK2 and yet promotes the p38 MAPK (Zaheer and Lim, 1996 and 1998).

[0140] Findings suggest that positive and negative regulation of MAPK activity are associated with loss of normal growth control and may be involved in carcinogenesis of colon cancers. Jun kinases such as JNK2 (MAP kinase 9) mediate signal transduction of pro-inflammatory cytokines and cellular stress (Uciechowski et al., 1996).

[0141] CD40 is a receptor on the surface of B-lymphocytes, the activation of which plays critical role in B cell proliferation and differentiation. CRAF1, (CD40 receptor-associated factor 1) encodes a protein that interacts directly with CD40 receptor (Cheng et al., 1995). Its upregulation in the co-culture is perhaps a main determinant of lymphoepithelial crosstalk as discussed above.

[0142] The c-myc gene is commonly amplified and over-expressed in many human tumors (Ryan and Birme, 1996). A member of the myc family of helix-loop-helix transcription factors, c-myc is integral in controlling cell growth and promotes cell proliferation and transformation by activating growth-promoting genes (Thompson, 1998). Prothymosin-α (PT-α) is a nuclear protein and its expression is associated with alterations in the proliferative state of cells and has been reported to be regulated by the c-myc gene in vitro. (Smith, 1995; Mon et al., 1993). The increased activity of c-myc in this model is likely to result in the increase in RT-α mRNA.

[0143] PKC-α protein levels regulate certain pathways that lead to the expression of differentiation-dependent genes. In a series of antisense transfection experiments where PKC-α expression in CaCo-2 cells was almost completely deleted, enhanced proliferation and a marked decrease in differentiation was observed, as well as a more aggressive transformed phenotype (Scaglione-Sewell et al., 1998). In a similar fashion, the lack of PKC-α mRNA detected in the co-culture ‘M cells’ may underlie some of the phenotype changes featured.

[0144] Glutathione S-transferase A1 (GSTA1) is a member of a multigene family of detoxification and metabolizing enzymes. Induction of GST enzyme activity has been demonstrated to act as a potent anti-proliferative and differentiating agent in Caco-2 cells (Stein et al., 1996) suggesting a similar role in the ‘M cell.’

[0145] Transcription factor GATA-2 is thought to maintain and promote the proliferation of early haematopoietic progenitor cells.

[0146] The placenta growth factor (PLGF) is a member of the vascular enciotheial growth factor (VEGF) family of growth factors. In addition to PLGF, VEGF mRNA was enhanced in the co-culture cells. These growth factors play a crucial role in angiogenesis during development and/or repair (Andre et al., 2000). The augmented transcription of their mRNA is consequently not a surprising find. However, hypoxia and energy depletion are known to induce angiogenesis by increasing VEGF, expression and so the possibility that the co-culture conditions are responsible for these genes induction cannot be ruled out ratherthan a deliberate mechanism of neogenesis in M cell formation. VEGF receptor 1 (VEGFR1); the receptor for VEGF and PLGF, mRNA is down-regulated and is possibly a consequence of desensitization of the receptor by VEGF and PLGF binding, initiating a reduction in the receptor's RNA.

[0147] Coinciding with the above actions, the absence of growth factors such as insulin-like growth factor-binding protein 3 (IGFBP3) and keratinocyte growth factor (KGF) may be modulating enterocytic cell proliferation and differentiation.

[0148] Caco-2 cells have been shown to express the type I IL-1 R. (Varilek et al., 1994) II-1Rα binds IL-1 and mediates cell signalling particularly signalling involved in cell proliferation (French et al., 1996). The expression of IL-1 R can be enhanced by IFN-γ (Varilek et al., 1994). Therefore, the expression of IL-1 R type 1 mRNA in the co-culture is interesting when considering the significant expression of IFN-1 expressed in supernatants of the co-culture model.

[0149] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of cyclin D1, PLC-L, GRB2, ERK3/MAPK6, ERK1, ERK3, JNK2, CD40, CRAF1, C-MYC, PT-α, IL-R, PKC-α, GSTA1, GATA-2, and PLGF.

Differentiation

[0150] Development of cells or differentiation is dictated by the expression of a cell's genes specific to that cell. This is a particularly important aspect with regards to M cells.

[0151] The cortical cytoskeleton not only provides structural support to the plasma membrane but also contributes to important dynamic processes such as endocytosis, exocytosis, and transmembrane signalling pathways. Ezrin, or villin 2, is an F-actin associated molecule and is concentrated in surface projections such as microvilli and membrane ruffles where they link the microfilaments to the membrane and has been reported to be in abundance during development and differentiation of the intestinal epithelium. It was reported that hepatocyte growth factor (HGF/SF) could stimulate the tyrosine phosphorylation of ezrin in a human colon epithelial cell line, which induced the ezrin associated membrane ruffling. It is interesting to note that both hepatocyte growth factor activator (HGF activator) and hepatocyte growth factor-like protein were both upregulated in the co-culture model and taken with the augmented ezrin mRNA the induction of these genes would appear to underlie the mechanism involved in the morphogenesis observed in M-cells.

[0152] These data demonstrate that the expression of the ezrin gene is being regulated at the level of mRNA due to effects incurred by the B-cells. It is particularly relevant considering the observations of villin diffusely displayed in M-cells.

[0153] One method of actin cytoskeletal reorganization is controlled by the LIMK-1 serine/threonine kinase, which acts by phosphorylating cofilin and subsequently Rac (as previously reported). However, LIMK-1 was deleted in the co-culture model and would appear to rule out the Rac-mediated mechanism of actin reorganization in the M cell model.

[0154] The cadherin family of cell adhesion molecules play important role in cell-cell adhesion during tissue differentiation. They have been reported to be linked to the actin cytoskeleton by catenins located in the cytoplasmic compartment of the cell. The specific expression of NCAD in the co-culture suggests a distinct gene involved in the cytoskeletal structure.

[0155] Previous reports have shown that neogenin is closely related to the human tumor suppressor molecule DCC (deleted in colorectal cancer) and together they constitute a subgroup of Ig superfamily proteins that have shown to be essential for terminal differentiation of specific cell types in the adult including the human colon. These parallels suggest that neogenin, like DCC, is functionally involved in the transition from cell proliferation to terminal differentiation of specific cell types. Its absence in the co-culture model might represent a period of continued proliferation for the cells and allow a longer period of proliferation.

[0156] The helix-loop-helix (HLH) family of transcription factors has been shown by others to play a central role in the regulation of cell growth, differentiation and tumorigenesis. Of particular interest, when HLH 1 R21 was over-expressed in mouse NIH3T3 cells, it induced a morphologically transformed phenotype.

[0157] Other genes associated with differentiation including Myeloid cell nuclear differentiation antigen (MNDA) and the LHX1 gene. The LHX1 gene is a member of the LIM/homeobox (Lhx) gene family. It has been shown that it codes for a transcriptional regulatory protein involved in the control of differentiation and development.

[0158] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of HGF activator, ezrin, NCAD, MNDA, and LHX1.

Adhesion

[0159] It is clearly evident that modification of the M cell apical surface is a determining factor in M cell apical membrane adherence, and thus, uptake and transport of macromolecules/microorganisms and targeting epitopes on the surface of M cells has been used to promote further adherence and uptake of particles in vaccinology. The specificity of these markers is not only useful for vaccine strategies but also represents targets for understanding adhesion and uptake of bacteria and viruses. Adhesion is not privy to the apical surface. Adhesion molecules on the basolateral surface of M cells, such as cadherin 2, neural cell adhesion molecule, integrin alpha 3, leukocyte adhesion glycoprotein p150, integrin beta 4 are understood to be involved in leukocyte migration and in the development/organization of lymphoid nodules in Peyer's patches. Genes expressed/induced in the co-culture can provide an insight into the mechanisms involved and are discussed below.

[0160] The tyrosine kinase receptor TIE 1 is normally located in vascular endothelial and haematopoietic cells and is largely involved in the proliferation and differentiation of miniature haematopoietic cells and would be an appropriate gene specific for M cells. In the brain, TIE mRNA and protein is significantly elevated in lesions composed of abnormal vasculature called arterioyenous malformations (AVMs) and the surrounding vasculature. Like AVMs, the significant upregulation of TIE in M cells may indicate some ongoing neogenesis, and depending on the receptor's polarity could be of potential use in vaccine targeting.

[0161] The neuronal cell adhesion molecule L1 (NCAML1) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily and is generally associated with development of the nervous system. As a potent promoter of neurite growth, it is allied with plastic changes. In nerve growth it interacts with the actin cytoskeleton via an ankyrin linkage and promotes specific distribution of F-actin. Such flexibility is ideal in the M cell scenario.

[0162] The integrin family consists of a series of related alpha beta heterodimers involved in a variety of cell-matrix and cell-cell adhesion functions. The α3β1 integrin is a multiligand extracellular matrix receptor found on many cell types and can function as a receptor for fibronectin, laminin, and collagen. Phagocytosis of molecules by breast cells has also been reported to involve this adhesion molecule, thus, it would appear a suitable candidate as an adhesion target on M cells.

[0163] The leukocyte adhesion glycoprotein p150 (CD11 C antigen), also a member of the integrin family, is involved in leukocyte sequestration via interaction of CD11/CD18 similar to that of ICAM-1.

[0164] In stratified epithelia p4 integrin (CD104 antigen) has been shown to be important for proper differential expression and crucial for stable adhesion to die basement membrane through its ability to attach externally to laminin and internally to the keratin cytoskeleton. Interestingly, during human intestinal organogenesis receptors have been shown to occur. This integrin would appear to play an important role in epithelial cell-matrix interactions during development but particularly in M cell development.

[0165] CD44 is a major surface adhesion molecule involved in cell-cell and cell-matrix interactions and lymphocyte homing and activation. The observed enhanced expression suggests that this molecule is an important feature in the activities of M cells. A non-receptor tyrosine kinase, C-src protooncogene (SRC1) has been shown to cause overexpression of CD44 in the intestine. As well as its effects on proliferation, the enhanced activity of SRC1 seen in the M cell model would appear to have major effects on cell adhesion properties of the M cell. Hepatocyte growth factor activator (HGF activator) is a serine protease produced and normally secreted by the liver. It has been documented as stimulating reparative processes in intestinal epithelial cells and could be why its activity is enhanced in this model. However, stimulation of CD44 in colonic epithelial cells has been reported to augment c-met, the HGF receptor. This in turn stimulates the “inside-out signalling causing an amplified expression of integrins that leads to an increase in vascular adhesion to the epithelium.

[0166] It has been reported that the glutamate receptor (NMDA) is generally associated with learning and memory, highly plastic processes in the brain. The high density of NMDA receptors reflects similar plastic changes seen in the co-culture model but would also act as a target epitope for drug delivery.

[0167] TKT is a tyrosine-kinase receptor related to TRK and is a member of cell adhesion kinase receptor family. Ephrin (type A) is a tyrosine kinase receptor that has been reported to be involved in neogenesis and tumor formation. Sp1 is a nuclear protein constitutively expressed and mediates basal promoter activity and is the main Vitamin-D receptor promoter in intestine. These are all potential target sites relevant to M cells.

[0168] Many of the receptors/cell surface antigen ‘deleted’ (not detectable) in the co-cultures could be putative negative markers of M cells. A good example is the laminin receptor a7β1 integrin. Expression of the a7β1 integtin correlates with human intestinal cell differentiation and could be used in a similar fashion that was applied with sucrase isomaltase and alkaline phosphatase.

[0169] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of cadherin 2, neural cell adhesion molecule, integrin alpha 3, leukocyte adhesion glycoprotein p150, integrin beta 4, TIE, NCAML1, α3β1 integrin, CD11C antigen, CD104 antigen, CD44, NMDA, TKT, ephrin (type A), and Sp1.

Transport

[0170] The RAB proteins are reported to be regulators of polarized membrane traffic in epithelial cells. The RAB3B is localized to the apical pole very near the tight junctions between adjacent epithelial cells where it is reported to be a possible regulator of apical and/or jupctional protein traffic in epithelial tissues. RAB3B is highly homologous to a brain-specific RAB3 isoform (RAB3A) that targets the presynaptic nerve terminal, where it is reported to regulate exocytosis.

[0171] In polarized cells, the small GTPase Rab5a is localized to the plasma membrane, clathrin-coated vesicles, and early endosomes and is a regulator of transport between the plasma membrane and early endosomes. The decreased expression of RAB5a seen in the co-culture may deregulate the rate of endocytosis and/or vesicle fusion and could possibly release ‘the brake’ on vesicle trafficking.

[0172] RAB6 is another ras related protein also a regulator of intracellular transport in mammalian cells. It controls intra-Golgi transport, either acting as an inhibitor in anterograde transport or as a positive regulator of retrograde transport. Like RAB5a, the pronounced decrease seen in mRNA transcription could be a means of subverting transport regulation in epithelial cells and so optimize the process as observed in M cells.

[0173] Protein kinase C (PKC) and the actin cytoskeleton are critical effectors of membrane trafficking in mammalian cells. The F-actin cross-linking protein myristoylated alanine-rich C kinase substrate (MARCKS), a substrate for PKC, has been reported to be a component of the mechanism of endocytosis.

[0174] TIR or p71 plays a key role in the control of cell proliferation through the binding of transferrin, the major iron-carrier protein. Located on both apical and basolateral surfaces, the transferring receptor has the ability to internalize and recycle to the surface. Indeed experiments by Hughson and Hopkins (1990) demonstrate pathways from the apical and basolateral surfaces meet in an endosomal compartment. Furthermore, Shah and Shen (1994) discovered that the fungal metabolite brefeldin A (BFA) could relocate receptor distribution and enhance TfR mediated transcytosis. The increased expression of this mRNA in the M cell model suggests a potential delivery mechanism of protein drugs across the intestinal epithelium present in M cells that could be exploited.

[0175] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of a RAB protein, PKC, and TfR.

Signal Transduction

[0176] In order for a cell to respond to extracellular signals, which cause it to alter gene expression or cellular function, it must involve the activation of a signal transduction cascade. There are many different types of signalling cascades, which can be unique to a specific type of stimulus. There are two main mechanisms by which these cascades transmit their signal, either through the regulation of enzymes, which produce second messenger molecules or through the regulation of protein phosphorylation. The activation of these cascades is usually mediated through specific cell surface or intracellular receptor proteins. The receptor protein recognizes the incoming extracellular signal and responds accordingly, initiating a specific series of intracellular signal that direct the cell's behavior. A number of genes involved in intracellular signalling were upregulated or induced in the M cell model and are discussed below.

[0177] A member of the Janus family of tyrosine kinases, which are non-receptor protein kinases, Jak3 is involved in intracellular signalling mediated by cytokines and growth factors such as IL-2, IL-4, and IL-7. Jak3 has been reported to play a crucial role in Peyer's patch organogenesis. Mutant mice deficient in Jak3 presented defects in lymphocyte production and the absence of Peyer's patch structures. Its induced expression suggests a greater level of activity and possibly a major requirement underlying the M cell phenotype ‘switch’.

[0178] The nuclear zinc-finger transcription factor, early growth response factor-I (EGR-1) is an immediate-early gene product expressed in response to diverse stimuli and is involved in growth, development, and differentiation. EGR-1 has been reported to function in growth regulation and suppression of cell transformation by transactivation of the TGFβ gene. TGFβ is capable of stimulating the synthesis of extracellular matrix proteins that can potentially stabilize epithelial cell contact with the substratum. In addition EGR-1 also plays a role in the immune response, regulating targets such as IL-2, CD44, ICAM-1, and TNF. Taken together the considerable induction of EGR-1 mRNA emphasizes the importance of this protein's involvement in M cell behavior.

[0179] CaM kinase IV (CAMK IV) is involved in Ca2+-dependent mechanism for regulating MAP kinase pathways. Many kinases activity has been observed to be enhanced in this model and so it is logical that CAMK IV expression is induced as a requirement to function.

[0180] The tyrosine kinase Tnk1 has been reported to be involved in signalling pathways involving development in adult tissues and in cells of the lymphohaematopoietic system.

[0181] Epithelial discoidin domain receptor 1 (EDDR1) mRNA was reduced in the co-culture. EDDR1 is a collagen receptor involved in controlling cellular responses to the extracellular matrix (ECM). The decrease in this gene would implicate it in the reorganization of the M cell in relation to the ECM.

[0182] cAMP-dependent protein kinase type I beta regulatory subunit (PRKAR1 B) stimulates growth by modulating the signalling of camp via its regulation of cAMP-dependent protein kinase (PKA). PRKAR1 B's reduction in the co-culture model may represent an inhibitory role in the cell's growth counterbalancing the proliferative signals.

[0183] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of Jak 3, EGR-1, TNK1 and CAMK IV.

Protection and Repair

[0184] Chaperones such as HSP40 and HSP70 participate in many biological processes in which protein folding is involved. These include protein translocation, protein translation, protein assembly and disassembly, and protein degradation. It is understandable that such genes would be induced considering the evolving processes of a phenotype ‘switch.’ However heat shock protein production has been reported to be induced as a result of harsh changes in their environmental conditions such as stress, ishaemia or hypoxia resulting in protein damage. Therefore it cannot be ruled out that the induction of these genes is in fact a protective measure as a consequence of the adverse conditions in the co-culture.

[0185] HSP60 has been observed in highly replicating cells e.g. short-living epithelial cells of the intestine. Involved in the import and refolding of nuclear-encoded proteins destined for the mitochondrial matrix.

[0186] The 27-kDa heat shock protein (HSP27) is expressed in a variety of tissues, including gut epithelia and in the absence of stress has been reported to regulate actin filament dynamics. Hsp27 induction in the M cell model like the other heat shock proteins (IISPs) may be active in development of resistance to stressful conditions. Activation of HSP27 can contribute to agonist-induced phosphorylation-modulated reorganization of the actin cytoskeleton and, in the case of stress activation, provides an actin-based adaptive response of cells to the new environmental conditions, and is ideal candidate for the plasticity seen in M cells.

[0187] Expression of receptors for fMLP on human phagocyles is well established, but there is conflicting evidence regarding the potential expression of fMLP receptors on other cells within the mucosa, particularly the epithelial cells. The reported observation of the receptor for the chemotactic peptide fMLP supports the notion of the intestinal epithelial cell as an early “sensor” of infection and inflammation. It has been reported that, fMLP, present in abundance in the lumen of the gut and that activation of fMLP receptors induces cytotoxic effects such as lysosomal release and superoxide generation. Thus, it would appear that their presence would be a defensive role in the event of infection of microorganisms.

[0188] Glutaredoxin (thioltransferase) is a small, heat-stable protein catalyzing glutathione-dependent disulfide oxdoreduction reactions in a coupled system with NADPH, GSH and glutathione reductase. It is important in regulating cell metabolism through the inactivation of oxidated transcription factors thought to be important in cellular responses to oxidant stress. This modulation of transcription factors' binding activity has been demonstrated for a number of transcription factors, including NF-kB/Rel proteins, Fos and Jun proteins and nuclear factor I (NFI) family of transcription factors. The induction of such a gene would appear to provide a protective role and is particularly influential on a number of key transcription factors.

[0189] CREB has been implicated as having prominent role in protection. Over-expression of the gene was reported to reverse hypoxia elicited TNF induction. This infers that the increase in the cAMP responsive element binding protein (CREB) mRNA is possibly a protective response to conditions.

[0190] Inactive in cells under normal conditions, gadd153 expression is markedly induced in response to a variety of cellular stresses, including nutrient deprivation, DNA damage, and oxidative stress (e.g. free radicals) which normally leads to growth arrest. The arrest in growth is thought to allow critical repair processes to be carried out before any further cell cycling. It would appear that the gadd153 expression in the co-culture is for reparative purposes.

[0191] The excision repair proteins XPG and XPD have been reported to be involved in nucleotide repair. In addition, mRNA for ubiquitin-conjugating enzyme (likely to be involved in post-replication repair and induced mutagenesis, RAD23, and ataxia telangiectasia are also expressed in the co-culture. Their expression, coinciding with gadd153 suggests there is a high degree of impairment to genes in the M cell model.

[0192] Interleukin-13 (IL-13) is a potent anti-inflammatory cytokine and has been reported to have the same protective properties in inflammation as IL-4 through its ability to modulate and suppress pro-inflammatory cytokines. It is puzzling that in an environment with a high level of pro-inflammatory cytokines produced that IL-13 mRNA is in fact reduced. One possible explanation might be its anti-adhesion effect. It has been reported that IL-13 (secreted from lymhocytes) down regulated cell adhesion molecules in colonic epithelium and so the role of IL-13 in the co-cultured cells is modulating cell adhesion properties and not inflammation.

[0193] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group consisting of HSP40, HSP70, HSP60, HSO27, fMLP-related receptor, HSP27, glutaredoxin, CREB, gadd 153, XPG, XPD, ubiquitin, conjugating enzyme, RAD 23, and ataxia telengiectasia.

Apoptosis and Programmed Cell Death

[0194] In programmed cell death, apoptosis is programmed in the sense that a genetically directed ‘clock’ selects a given time for the death of certain cells. It has been reported that it provides an important mechanism for the maintenance and renewal of cells in the gut and in development. However, for the epithelium to maintain its barrier functions, the level of apoptosis needs to be regulated, and this is ‘checked’ by several signal transduction systems. Toxic insult or lack of factors that maintain cell survival can also lead to apoptotic death of the cell.

[0195] It has been reported that over-expression of c-fos and c-jun (constituents of the AP-1 transcription factor) in the intestine correlates with programmed cell death and subsequent cellular regeneration. Other studies have demonstrated increases in both proximal jejunum and colon jun mRNA level coincide with a period of major changes in intestinal cell proliferation). The c-jun protein product involved in activation of AP-1, transcription is enhanced when it is phosphorylated by stress-activated protein kinases of which there are many in the M cell model.

[0196] As intestinal epithelial cells reach the villus apex they undergo apoptosis and, are shed and, in normal circumstances, caspases, a family of cysteine proteases, play a central role in initiating, amplifying, and executing apoptosis. The pattern of caspase activation in this process is not understood. It is interesting to note that the apoptosis regulator, bcl-x, and caspase 9 are induced in the co-culture. The bcl-x gene plays an important role in the regulation of programmed cell death (PCD), depending on its splice variant the bcl-x protein can accelerate apoptosis or delay/prevent programmed cell death (as previously reported). Bcl-x controls apoptosis mechanisms at points upstream of caspase activation. Perhaps, it is responsible for the marked induction of caspase-9. Caspase-9 is a caspase initiator. Once activated, it can proteolytically activate other caspases (including 3, 6 and 7), which in turn activate caspase-2 and 6 (as previously reported). Inhibitor of apoptosis protein 2 (HIAP2) binds to and inhibits caspase-3. Its expression is a mechanism of regulating cell death depending on the particular cellular or environmental signals. Therefore, its absence in the co-culture cells and the increased activity of caspase-9 allows caspase-3 unchecked pro-apoptotic activity.

[0197] The death domain receptor 3 (DDR3) member of the TNFR family can induce apotosis as previously reported. Its mRNA expression is also reduced in the co-culture model.

[0198] In view of the foregoing, in the method of the invention for increasing the level of a protein in a PP cell, which comprises delivering a nucleic acid coding for a protein, the protein may be selected from the group selected from: bcl-x and capase-9 and more generally in view of the foregoing may be selected from the group consisting of

[0199] cyclin D1, PLC-L, GRB2, ERK3/MAPK6, ERK1, ERK3, JNK2, CD40, CRAF1, C-MYC, PT-α, IL-R, CD40, C-MYC, PKC-α, GSTA1, GATA-2, PLGF, ezrin, HGF activator, hepatocyte growth factor-like protein, NCAD, MNDA, LHX1, TIE-1, NCAML1, CD104, CD44, SRC1, NMDA, TKT, ephrin (type A), Sp1, RAB proteins, PKC, TIR, Jak3, EGR-1, TNK1, CAMK IV, HSP40, HSP70, HSP60, HSO27, fMLP-related receptor, HSP27, glutaredoxin, CREB, gadd153, XPG, XPD, ubiqitin-conjugating enzyme, RAD23, cadherin 2, neural cell adhesion molecule, integrin alpha 3, leukocyte adhesion glycoprotein p150, integrin beta 4, TIE, NCAML1, α3β1 integrin, CD11C antigen, CD104 antigen, CD44, NMDA, TKT, ephrin (type A), and Sp1, a RAB protein, PKC, and TfR, bcl-x and capase-9

Example 6

Targeted Gene Delivery

[0200] Delivery of genes, gene fragments, oligonucleotides or other nucleotide fragments or analogues of the present invention to a living organism can be accomplished by methods currently available in the prior art. For example, various recombinant viruses have been used for the oral delivery of genes, such as adenovirus, retrovirus, adeno-associated virus, vaccinia virus, lenti-virus and plant-derived viruses, wherein the viral genome is replaced with an expression vector for the gene of interest. See, David T. Page and Sally Cudmore (2001). Innovations in oral gene delivery: challenges and potentials. Drug Discovery Today, Vol. 6, No. 2, pp 92-101. Viral mimetic particles such as virosomes and various types of polymers and liposomes, such as cationic and fusogenic, are also employed for gene delivery. See, U.S. Pat. Nos. 4,885,172, 5,047,245, 5,171,578, 5,059,421, 5,399,331, 5,204,112, 1,252,263, 5,376,452, 5,552,155, 6,120,797, 6,087,325, 6,143,716. Examples of polymers are PLGA, PLA co-polymers, chitosan, and fumaric acid/sebacic acid co-polymers. For these systems, the polymer or liposome is formed from component parts in a solution of the gene expression vector, thus encapsulating the genes when particles are formed. Cationic lipids such as DOTAP and polyethylenimine are commonly used whereby the gene expression vector is complexed with and protected by the lipids. (See, Ogris M. et al. (2001). DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and pegylation on internalization and gene expression. AAPS PharmSci, 3 (3), article 21). Agents such as protamine are used to condense DNA, which due to the reduction in size of the DNA particles are more easily taken up by cells. Recombinant live bacteria (e.g. Shigella spp, Salmonella spp.) have also been exploited for gene delivery to the gut. Oral bioavailability enhancers, (e.g. sodium caprate, Elan's PROMDAS technology) could be used to increase uptake of a gene or encapsulated gene formulation.

[0201] In all cases the delivery systems can be targeted with various ligands on the surface of the particles in order to enhance binding to specific cells type and/or to enhance uptake. These ligands could be peptides, proteins, antibodies, peptidomimetics, and lipids that recognize or are being recognized by specific sites/receptors on the cell surface (Maruyama K. (2000). In vivo Targeting by Liposomes. Biol. Pharm. Bull., 23(7), 791-799).

[0202] The targeting ligands may be peptide based, peptidomimetic based, antibody based, single chain antibody based, small organic molecule based. The targeting ligands may also be natural substrates for such receptors, transporters or other cell surface molecules found on the surface of M cells or other cell types found in Peyer's patch. The targeting ligands may be engineered so as to be genetically expressed on the surface of viruses, bacteriophages, virosomes, bacteria or other organisms, which can be utilized for vaccine delivery in the gut. Furthermore the targeting ligands can be presented either as direct conjugates to antigens, or on the surface of drug-loaded particulates such as liposomes, PLGA particles, other particulates and at the same time retain recognition by and interaction with the receptors, transporters or other cell surface molecules found on the surface of M cells and/or other cells of Peyer's patch tissue.

[0203] Examples of peptides that target the gastro-intestinal tract, in particular, membrane translocating peptides useful for vaccine delivery to M cells along with M cell specific targeting ligands are described in Table 4.

[0204] Further, targeting ligands can be genetically engineered into the surface coats of viruses, bacteriophages or bacteria, conjugated directly to antigens conjugated to the lipids in liposomes by covalent methods or streptavidin-biotin linkages, or coated onto the surface of polymers after particle formation (Torchilin V. P. et al. (2001) Proc. Natl. Acad. Sci. USA, Vol. 98, Issue 15, 8786-8791, July 17.

[0205] TAT peptide on the surface of the liposomes affords their efficient delivery even at low temperature and in the presence of metabolic inhibitors; Lestini et al. (2002). Surface modification of liposomes for selective cell targeting in cardiovascular drug delivery. J. Controlled Release, 78, 235247; Dokka S. et al. (1997) Cellular delivery of oligonucleotides by synthetic import peptide carrier. Pharm. Res., vol. 14, No. 12, 1759-1764); Wu Y et al. (2000). Gene transfer facilitated by a cellular targeting molecule, retrovirus protein σ1. Gene Therapy, 7, 61-69).

[0206] When the delivery of the gene to M cells in the gut is designed to prime or boost the immune system, the genes can be co-delivered/co-encapsulated with adjuvants (e.g. MF59, alum, saponin, QS21, MPL, bacterial toxins such as Lt, CT or mutants there-of, CPG motif nucleotides). Immune response could be boosted at a later stage by methods such as subcutaneous administration of an adjuvant.

[0207] In some cases it may be desired to shut off expression of certain genes, so as to enhance the adoption by enterocytes of an M cell phenotype. This can be achieved by the delivery, by methods outlined above, of antisense oligonucleotides, ribozyme, or RNA-interference molecules specific to the gene of interest.

12TABLLE 4Peptides that Target to and/or Enhance Uptake Across the GITSEQ. ID NO:PEPTIDE SEQUENCESSEQ. ID NO:ADDFMGCMLTLPTSLGGEGSPYNYYDTHEANGPHSEQ. ID NO:TPTTTATWGTTGPVDLSSLHLLRHPCREFSEQ. ID NO:MSPDHQYALQSSPVLPCCRPLLVDSDYIHSSEQ. ID NO:RGYGRLAESCCVNRCIRTVGGCGNSPASDILSATSEQ. ID NO:STPGRGSGRDTGANNPADTPYANPSHRDTILSLDPSLLSEQ. ID NO:RQHLWRDLHGPRFRDTNTGVAGTFSPPVSVADTHRTPDSEQ. ID NO:SFSNLTAGDEEDDHFSGGRFNHANLTSRSHNRGQLASSASEQ. ID NO:RQSVLDSWGGKTSVTGLSERYYASHSHTSAPTPHYASHSSEQ. ID NO:RQWVGDRDAGEGNTWVDEKYSRDANVISYRSHNHASQGTLSEQ. ID NO:RASDCDVECNLRWVEDVGGVWYAKTVSRMLSTTSEQ. ID NO:RQSAGFLGFAPTNIDDTSFNAGCGDTLAIPCRHRSSLISPARPPSEQ. ID NO:RSGAYESPDGRGGRSYVGGGGGCGNIGRKHNLWGLRTASPACWDSEQ. ID NO:SPRSFWPWSRHESFGISNYLGCGYRTCISGTMTKSSPIYPRHSSEQ. ID NO:SSSSDWGGVPGKWRERFKGRGCGISITSVLTGKPNPCPEPKAASEQ. ID NO:RVGQCTDSDVRRPWARSCAHQGCGAGTRNSHGCITRPLRQASAHSEQ. ID NO:SHSGGMNRAYGDVFRELRDRWNATSHHTRPTPQLPRGPNSEQ. ID NO:SPCGGSWGRFMQGGLFGGRTDGCGAHRNRTSASLEPPSSDYSEQ. ID NO:RGAADQRRGWSENLGLPRVGWDAIAHNSYTFTSRRPRPPSEQ. ID NO:SGGEVSSWGRVNDLCARVSWTGCGTARSARTDNKGFLPKHSSLRSEQ. ID NO:SDSDGDHYGLRGGVRCSLRDRGCGLALSTVHAGPPSFYPKLSSPSEQ. ID NO:RSLGNYGVTGTVDVTVLPMPGHANHLGVSSASSSDPPRRSEQ. ID NO:RTTTAKGCLLGSFGVLSGCSFTPTSPPPHLGYPPHSVNSEQ. ID NO:SPKLSSVGVMTKVTELPTEGPNAISIPISATLGPRNPLRSEQ. ID NO:RWCGAELCNSVTKKFRPGWRDHANPSTHHRTPPPSQSSPSEQ. ID NO:RWCGADDPCGASRWRGGNSLFGCGLRCSAAQSTPSGRIHSTSTSSEQ. ID NO:SKSGEGGDSSRGETGWARVRSHAMTAGRFRWYNQLPSDRSEQ. ID NO:RSSANNCEWKSDWMRRA.CIARYANSSGPARAVDTKAAPSEQ. ID NO:SKWSWSSRWGSPQDKVEKTRAGCGGSPSSTNCHPYTFAPPPQAGSEQ. ID NO:SGFWEFSRGLWDGENRKSVRSGCGFRGSSAQGPCPVTPATIDKHSEQ. ID NO:SESGRCRSVSRWMTTWQTQKGGCGSNVSRGSPLDPSHQTGHATTSEQ. ID NO:REWRFAGPPLDLWAGPSLPSFNASSHPRALRTYWSQRPRSEQ. ID NO:RMEDIKNSGWRDSCRWGDLRPGCGSRQWYPSNMRSSRDYPAGGHSEQ. ID NO:SHPWYRHWNHGDFSGSGQSRHTPPESPHPGRPNATISEQ. ID NO:RYKHDIGCDAGVDKKSSSVRGGCGAHSSPPRAGRGPRGTMVSRLSEQ. ID NO:SQGSKQCMQYRTGRLTVGSEYGCGMNPARHATPAYPARLLPRYRSEQ. ID NO:SGRTTSEISGLWGWGDDRSGYGWGNTLRPNYIPYRQATNRHRYTSEQ. ID NO:RWNWTVLPATGGHYWTRSTDYHAINNHRPSIPHQHPTPISEQ. ID NO:SWSSWNWSSKTTRLGDRATREGCGPSQSDGCPYNGRLTTVKPRTSEQ. ID NO:SGSLNAWQPRSWVGGAFRSHANNNLNPKPTMVTRHPTSEQ. ID NO:RYSGLSPRDNGPACSQEATLEGCGAQRLMSTRRKGRNSRPGWTLSEQ. ID NO:SVGNDKTSRPVSFYGRVSDLWNASLMPKRTPSSKRHDDGSEQ. ID NO:TNAKHSSHNRRLRTRSEQ. ID NO:SDNAKEPGDYNCCGNGNSTGSEQ. ID NO:RTRLRRNHSSHKANTSEQ. ID NO:PEPTIDE SEQUENCESSEQ. ID NO:GPHRRGRPNSRRSSKTSEQ. ID NO:GTSNGNGCCNYDGPPevers patch and/ or M cell specific targeting ligands:SEQ. ID NO:ATPPPWLLRTAPSEQ. ID NO:DGSIHKRNIMPLSEQ. ID NO:DYDSLSWRSTLHSEQ. ID NO:GEPTTDMRWRNPSEQ. ID NO:GLWPWNPVTVLPSEQ. ID NO:HMLNDPTPPPYWSEQ. ID NO:KPAYTHEYRWLASEQ. ID NO:LETTCASLCYPSSEQ. ID NO:LGTDWHSVSYTLSEQ. ID NO:LGTLNAGVPGFPSEQ. ID NO:LTHSKNPVFLSTSEQ. ID NO:LVPTTHRHWPVTSEQ. ID NO:LVSNARGFNNLSSEQ. ID NO:NTRIPEPIRFYMSEQ. ID NO:NVYTFHSMSPMPSEQ. ID NO:QHTTLTSHPRQYSEQ. ID NO:SDFSDTMPHRPSSEQ. ID NO:SIDTIQILSLRSSEQ. ID NO:SISWASQPPYSLSEQ. ID NO:SMVKFPRPLDSRSEQ. ID NO:SPTLGASVAQTNSEQ. ID NO:TMSPNVYYTAFGSEQ. ID NO:TQIPSRPQTPSQSEQ. ID NO:VCSNMYFSCRLSSEQ. ID NO:VPPHPMTYSCQYSEQ. ID NO:VPRLEATMVPDISEQ. ID NO:VPTKPELPVNFTSEQ. ID NO:WSSDLPQPASTYSEQ. ID NO:YITPYAHLRGGNSEQ. ID NO:NVYTDNTLSPTPSEQ. ID NO:LETTAASLCYPSSEQ. ID NO:SPYCLSACTTELSEQ. ID NO:LETTCASLCYPSSEQ. ID NO:VPPHPMTYSCQYSEQ. ID NO:VPPHPMTYSAQYSEQ. ID NO:VPPHPMTYSSQYSEQ. ID NO:YQCSYTMPHPPVSEQ. ID NO:VCSNMYFSCRLSSEQ. ID NO:VSSNMYFSSRLSSEQ. ID NO:DYDSLSWRSTLHGGHESSHSEQ. ID NO:GNPTSTMRWSEQ. ID NO:PWNSATVLSEQ. ID NO:NDPTAPPYMembrane Translocating Peptides:(underline denotes cyclization)SEQ. ID NO:KKAAAVLLPVLLAAPFITC-LCSEQ. ID NO:KKKAAAVLLPVLLAAPSEQ. ID NO:KKAAAVLLPVLLAAPREDLSEQ. ID NO:KKCAAVLLPVLLAAPCSEQ. ID NO:CAAVLLPVLLAACSEQ. ID NO:KKCAAVLLPVLLACSEQ. ID NO:CAAVLLPVLLCSEQ. ID NO:CAAVLLPVLCSEQ. ID NO:CAVLLPVLLAAPCSEQ. ID NO:CVLLPVLLAAPCSEQ. ID NO:CLLPVLLAAPCSEQ. ID NO:CLPVLLAAPCSEQ. ID NO:AAVLLPVLLAAPSEQ. ID NO:AAVLLPVLLAASEQ. ID NO:KKAAVLLPVLLASEQ. ID NO:AAVLLPVLLSEQ. ID NO:AAVLLPVLSEQ. ID NO:AVLLPVLLAAPSEQ. ID NO:VLLPVLLAAPSEQ. ID NO:LLPVLLAAPSEQ. ID NO:LPVLLAAPSEQ. ID NO:AAVLLPVLLAAKKKRKASEQ. ID NO:KKKRKAAAAVLLPVLLA

Example 7

[0208] Use of Bacterial Coatings to Convert Enterocytes to M Cells

[0209] Might be nice to have some type of claim capturing the concept from this section Use of bacterial coatings on PLGA particles, co-administered bacterial particles or pro-biotic yogurts as adjuvants for oral vaccination with PLGA particles. The invention is based on converting enterocytes to M cells by using specific bacteria in advance of, or along with the oral vaccine particle of interest. In doing so the capability of absorbing particles through M cells will be increased. This idea is not based on targeting but on the ability of live bacteria or active bacterial components to stimulate cytokine production in Peyer's patches, thus, enabling enterocyte-M cell conversion. As a result, an invention disclosed herein is a method of promoting enterocyte-M cell conversion, said method comprising orally administering an antigen, antigenic composition, or antigen-carrying particle to a person and either simultaneously with, or prior to, said administration, also orally administering a bacteria, or pro-biotic yogurts, or bacterial component to said person.

[0210] All references cited herein are incorporated herein by reference in their entireties.

13TABLE 5Miscellaneous GenBank Accession NumbersHuman Serum AlbuminNM_000477.3CalreticulinM84739

Dates for GenBank Records

[0211] To the extent the date of a GenBank record, ratherthan its version number, is relevant for purposes of incorporation by reference, the date of the record is the filing date of this application with the following exceptions:

14TABLE 2 Rat genesMar. 27, 2002D83697 through M10149Mar. 28, 2002Q03238 through NM_017218.2TABLE 3 Human genes with a fold change of 0.5 or lessApr. 02, 2002TABLE 2 Human genes with a fold change of 0.5 or lessApr. 02, 2002U76376.1 through XM_087242.1Apr. 03, 2002S90469 through M29366.1

[0212] The records specified for Mar. 27, 2002, Mar. 28, 2002, Apr. 2, 2002, and Apr. 3, 2002, do not include those of GenBank IDs: Q07912, P21145, P46734, Q92851, Q13490, NP—006168, P28360, P28347, Q06830, P20701, P01589, P05106, P35225, P17936, S18408, P17074, P10661, P35426, P09456, P22791, Q06486, P21708, Q03238, P10644, P54868, P10398, P48730, P31749, P27361, P25063, Q14012, P13866

15AMINO ACID SEQUENCES AND NUCLEOTIDE SEQUENCES CORRESPONDING TO SELECTEDCENBANK ID NUMBERSGENBANK ID: M81750VERSION M81750.1 GI:895928MVNEYKKILLLKGFELMDDYHFTSIKSLLAYDLGLTTKMQEEYNRIRITDLMEKKFQGVACLDKLIELAKDMPSLKNLVNNLRKEKSKVAKKIKIQEKAPVKKINQEEVGLAAPAPTARNKLTSEARGRIPVAQKRKTPNKEKTEAKRNKVSQEQSKPPGPSGASTSAAVDHPPLPQTSSSTFSNTSFTPNQETQAQRQVDARRNVPQNDFVTVVVLKATAPFKYESPENGKSTNFHATVASKTQYFHVKVPDINLKEKFVRKKVITISDYSECKCVMEIKEASSVSDFNQNFEVPNRIIEIANKTPKISQLYKQASGTMVYGLFMLQKKSVHKKNTIYEIQDNTGSMDVVGSGKWENIKCEKGDKLRLFCLQLRTVDRKLKLVCGSHSFIKVIKAKKNKEGPMNVNGENBANK ID: X59798VERSION X59798.1 GI:35631MEHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKMNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDIGENBANK ID: L27211.1VERSION L27211.1 GI:558656MEPAAGSSMEPSADMLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADFATLTRPVNDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPDGENBANK ID: U22398VERSION U22398.1 GI:790247MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDNEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLESGISGRPAAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRLRGENBANK ID: X51521VERSION X51521.1 GI:31282MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLNYVDNKGFPTMLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVEKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAERRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEMQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLVTLSSELSQARDENKRTRNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEALGENBANK ID: L04143.1VERSION L04143.1 GI:180574THIS ENTRY IS NOT CONTIGUOUS CENOMIC DNA. IT CONTAINS NUMEROUS PIECES OFINTRONS.1GAGCTCGGAT CCCATCGCAG CTACCGCGAT GAGAGGCGCT CGCGGCGCCT GGGATTTTCT61CTGCGTTCTG CTCCTACTGC TTCGCGTCCA CACAGGTGGG ACACCGCGGC TGGCTCCCCC121ACCGTGCCAC TACTCGCGAA CCCTGTGCCC TGGGAGGGTG CTACCGCCAT GGCATCCGCA181GACAGGACTG CGGGCCCTCA GTGGGCCTGC GTTCCAGCCT CCGGGGAGAC TCCAGGTGGC241CCTCGGACTC TCCGGCGCCC TGCCTCGCTC ACCTGCGCGA GGAGACCCCA GCTGCTGGTG301GTGGGGGACG CGAATCCGGG GTTCTTCGGG AATGGGGACA GCAAGAGGGG GTTAGGCGTG361AGCGAGGCTG CAGGCTCCGT GCGAGTTTGG GGTGGCTTTT GTGCCGACGT TGCGCGGGGG421CGGAGGCGGG GGCTCAGGGT TTGCACCGAG CGCCTTCTCT CTCGGTGCGA GGCCGGCCGC481AGCTTCCTTT TGTTAAAAGT TGCGTGTGTG TGACGGCGCC CGGGCTGCAG CCTCAACCTC541CTGGGCTTAA GTGATCTCCC ACCTCAGCCT CCCGCCTCAG CCTCCCATGT AGCTGGGAAA601ACAGGTTCCC ACTACCATGC CCAGCTAATG TTTTTTCTAG TTTTTGTAGA TGTGTTGGGC661GGTGGGGGCG TCTCACTGCG TTGCCCAGGC TGGTCTCGAA CTCCTAGGCT CAAGCAATCT721TCCCACCTCA GCCTCCCAGA GTGCTGGGAT TACAGGCGTG ACGACGGCAC CTGGCCAGCA781GTTTGTTCTT TAAACCCTGA AATGTATGTG AGGACCATGT GTCACACTAG CATGGACGTT841TTCCCAGCAT CTAGCATGGT GCTTTGTAGA TGATAATTAA TGAATAGGTA TTTGAATACA901TGGAGGCATG CATGGCTGAA TGAAGTGGCT GTTGTAAAAT TTCTAGGGTT CAGGTTTCAT961ATTCAGAGCC TAAAGTTTGC ATCTTATAAA CTAAATAGTT TCCTATCTAG GAAACCTATT1021TAGGCATTAG GGTGTTAAAA CAGGTGTATC ATTTTCTGCC TTAGTGTTTA GAGATTTGTG1081AATAGTTCTC CTTTTGATGA ACATTGCCAT GTAAAGAGAG TTATACAGAA ATAACTGAAT1141TCACACAGTT TTAAGGAAAA GCTATTCTAT GTCATGGTCA TGTATATTCT GCCAAAGAGA1201GTGACAGGCC AGTAGTTTCT TTTTTCTTTT TCCCCATAGT GTGAGATTTT GTTTCTGTTG1261TTTCTAAGCT GGGTGTCTGC ATGTCCACAC TGCGAAGATG GCCCATATCA GAATGAAAAC1321TTGACCCAAT TGTATGTTTA GCCCAGAGAA GGCTGGGGCA TTCAGCACAT CCTGGCTTGG1381GGACCAAATG TGACCCTCAG GATTAATTGA GGGTTGGAGA AAATAATTTT ATAGATGAAC1441TTAAGACATT TTAGACAGAA CTCTCTTTTC AGCCATAAAT AGCAGGGCAG CTTTGTCCTA1501TTTTTATTGT AGAGTACACA GAAGATGGAA CTCAGTATTG GAAGAAGTGC TTTATTTCGC1561CAAGGAAGAA GATCATACTC AACACGATTC TGTTTTTCTT GGCAGGCTCT TCTCAACCAT1621CTGTGAGTCC AGGGGAACCG TCTCCACCAT CCATCCATCC AGGAAAATCA GACTTAATAG1681TCCGCGTGGG CGACGAGATT AGGCTGTTAT GCACTGATCC GGGCTTTGTC AAATGGACTT1741TTGAGATCCT GGATGAAACG AATGAGAATA AGCAGAATGA ATGGATCACG GAAAAGGCAG1801AAGCCACCAA CACCGGCAAA TACACGTGCA CCAACAAACA CGGCTTAAGC AATTCCATTT1861ATGTGTTTGT TAGAGGTAAA TGCTTGGCTT TCTGCAGCAG GTCATGTCAC TTTAGGAGGG1921TTGCTTTTAT GACACCGCAG TTTCATCTAT GAAATGGCAA TAATGATAGT ACTGATCATG1981GGAGGGGCAA TTTGAAGATT AAATGAGATT AAGTGTAATG GTCCAAGCTT AGTGCGTGAT2041ACATGGAAAG CGTTTAATAA ATGTTAATTC TCAATAGTAC TAGATGGATA AATTTTGCTT2101TTGTTTACAC AGAAAAAAGC AGCCATTTGG GCCACTAGTC ATGAAAGGCA ACATATTAGA2161TCTTTAAAAG TGTTTCAGTG TCTGTGACCA GCCATTCCAA CTACTGATTT GGATATGCTT2221CTTATAGATC CTGCCAAGCT TTTCCTTGTT GACCGCTCCT TGTATGGGAA AGAAGACAAC2281GACACGCTGG TCCGCTGTCC TCTCACAGAC CCAGAAGTGA CCAATTATTC CCTCAAGGGG2341TGCCAGGGGA AGCCTCTTCC CAAGGACTTG AGGTTTATTC CTGACCCCAA GGCGGGCATC2401ATGATCAAAA GTGTGAAACG CGCCTACCAT CGGCTCTGTC TGCATTGTTC TGTGGACCAG2481GAGGGCAAGT CAGTGCTGTC GGAAAAATTC ATCCTGAAAG TGAGGCCAGG TACCTTGCTT2521TCTTATCTGC CTCTGGAGTT GAGAACTCAC TTATCTAAAG AGACTTCTCT TCTCGTTGAT2581CGTAAGCTGT ACACATTTGA GGAGAAATGG TAAATCAAAA TTTCATGCTA TAATACAAAT2641TATTTGAGGG GCCACATTTC TTTTCATTCT AGCCTTCAAA GCTGTGCCTG TTGTGTCTGT2701GTCCAAAGCA AGCTATCTTC TTAGGGAAGG GGAAGAATTC ACAGTGACGT GCACAATAAA2761AGATGTGTCT AGTTCTGTGT ACTCAACGTG GAAAAGAGAA AACAGTCAGG TGAGTGAATC2821GCTTCATTCT TCTCATGTTC TGTCTCTGTG GGAGATGATA AGTTTTCTCT TTCAGAAGAG2881TCTGTCCTGA AACTGCCTCG ACTAGTGCGT CTGTCAGAGG AGAAGTTAAT TGCTGCTATT2941TTTAATTTAT CTAGGAAAGA TTCTGAATAT AAATTATATG GTAATCTTCA TTTTTTTTTC3001TCCTTTTCTG AAACCAGCAG ACTAAACTAC AGGAGAAATA TAATAGCTGG CATCACGGTG3061ACTTCAATTA TGAACGTCAG GCAACGTTGA CTATCAGTTC AGCGAGAGTT AATGATTCTG3121GAGTGTTCAT GTGTTATGCC AATAATACTT TTGGATCAGC AAATGTCACA ACAACCTTGG3181AAGTAGTAGG TAAATACCTC TATGGGAATG TTTAAATTAC TGGCAGTAGT GAAAGAAGAA3241ATTATTAGAC AGTTTCTTTT TTATGTAAAT GGAATGTTGA ACAGATTCTT AGAATTTTGT3301TATCACTGAA TGAATGAAAA TTATCCTTGT AGCCTCTTGC AATGAAAGCA CAATTCTGTT3361TTTTTTGTCC AGTAGTTGTA GATAATGTTT CTTTCTGTCT TATTTCATTC TAATTAGATA3421AAGGATTCAT TAATATCTTC CCCATGATAA ACACTACAGT ATTTGTAAAC GATGGAGAAA3481ATGTAGATTT GATTGTTGAA TATGAAGCAT TCCCCAAACC TGAACACCAG CAGTGGATCT3541CTCTGAACAG AACCTTCACT GATAAATGGG AAGATTATCC CAAGTCTGAG AATGAAAGTA3601ATATCAGGTA AGAAATGGAC CTTGCCCTGG GGATTACACA TTACCCCCTT TTCCAGTGGG3661CTTATCAGAT CTTATTTCTG TAACCCGTAA ATCCACGAGA AGATACCTGG TAAAGAAGAA3721AGTCTATTTT GCTAATACTT TACTGAATTA AATGAGTTAT ATTTTTCCTC AAACAGGCAT3781AGATTTCCAG GTAGAAACTG AAAAAGACAT GCCTTCCAAG GCATGCTATC CACAGGTGAT3841TGACTAGTTG TCTTTTCTTT GTAGATACGT AAGTGAACTT CATCTAACGA GATTAAAAGG3901CACCCAAGGA CCCACTTACA CATTCCTAGT GTCCAATTCT GACGTCAATG CTGCCATAGC3961ATTTAATGTT TATGTGAATA GTAACTAACA TGAAGGGCTC TTTTAATTTT TTATTCTTTT4021AAGTTGTGGC TCGTGTTTGT AACAGCTGCA AGGACTCAAC TTGCTGTACT AAAGGTTGTA4081CGGATTTAGA GAGGGAGTGA AGTGAATGTT GCTGACGTTT TCCAGCACTC TGACATATGC4141CCATTTCTGT TTTCCTGTAG CAAAACCAGA AATCCTGACT TACGACAGGC TCGTGAATCC4201CATGCTCCAA TGTGTGGCAC CAGGATTCCC AGAGGCCACA ATAGATTGGT ATTTTTGTCC4261AGGAACTGAG CAGAGGTGAG ATGATTATTT TTGGCACTGC TTATAATGCA GAGGGGAAGG4321ACTGCAATTC ACTTGAATTT CAAATATGTT TTCTGATTTT TTTTAAAAAA GCTTTAACTT4381TGTTTTAAAA GTATGCCACA TCCCAAGTGT TTTATGTATT TATTTATTTT CCTAGAGTAA4441GCCAGGGCTT TTGTTTTCTT CCCTTTAGAT GCTCTGCTTC TGTACTGCCA GTGGATGTGC4501AGACACTAAA CTCATCTGGG CCACCGTTTG GAAAGCTAGT GGTTCAGAGT TCTATAGATT4561CTAGTGCATT CAAGCACAAT CGCACGGTTG AATGTAAGGC TTACAACGAT GTGGGCAAGA4621CTTCTGCCTA TTTTAACTTT GCATTTAAAG GTAACAACAA AGGTATATTT CTTTTTAATC4681CAATTTAAGG GGATGTTTAG GCTCTGTCTA CCATATCAGT CATGATTTTG AGCTCAATTA4741ACCCTCACTA AAGGGAGTCG ACTCGATCCC ATCCTGCCAA AGTTTGTGAT TCCACATTTC4801TCTTCCATTG TAGAGCAAAT CCATCCCCAC ACCCTGTTCA CTCCTTTGCT GATTGGTTTC4861GTAATCGTAG CTGGCATGAT GTGCATTATT GTGATGATTC TGACCTACAA ATATTTACAG4921GTAACCATTT ATTTGTTCTC TCTCCAGAGT GCTCTAATGA CTGAGACAAT AATTATTAAA4981AGGTGATCTA TTTTTCCCTT TCTCCCCACA GAAACCCATG ATGAAGTACA GTGGAAGGTT5041GTTGAGGAGA TAAATGGAAA CAATTATGTT TACATAGACC CAACACAACT TCCTTATGAT5101CACAAATGGG AGTTTCCCAG AAACAGGCTG AGTTTTGGTC AGTATGAAAC AGGGGCTTTC5161CATGTCACCT TTTTGGGTAC ACATAACAGT GACTTTAAGG AACTCCAGTG GCTTCCTTTG5221TTTTGTTCCA CCTGAAACAA TGAGTTTTCT GTGAAATTGC GCCCCTTTTG ATAGGTTTGC5281CATAGAGAAC ATCGTAGGAA AATGTCTCTG GACAACATTG TTTTTAATTC CTTTATTGAT5341TTTGAAACTG CACAAATGGT CCTTCAATTC CACCACCAGC ACCATCACCA CTTACCTTGT5401TGTCTTCCTT CCTACAGGGA AAACCCTGGG TGCTGGAGCT TTCGGGAAGG TTGTTGAGGC5461AACTGCTTAT GGCTTAATTA AGTCAGATGC GGCCATGACT GTCGCTGTAA AGATGCTCAA5521GCGTAAGTTC CTGTATGGTA CTGCATGCGC TTGACATCAG TTTGCCAGTT GTGCTTTTTG5581CTAAAATGCA TGTTTCCAAT TTTAGCGAGT GCCCATTTGA CAGAACGGGA AGCCCTCATG5641TCTGAACTCA AAGTCCTGAG TTACCTTGGT AATCACATGA ATATTGTGAA TCTACTTGGA5701GCCTGCACCA TTGGAGGTAA AGCCGTGTCC AAGCTGCCTT TTATTGTCTG TCAGGTTATC5761AAAACATGAC ATTTTAATAT GATTTTGGCA ATGCTAGATT ATAAACTGCT TGGAACATTT5821TTTTACCCAG ACTGTTGTTC TCTCTTGCTA GATTTTGTTT TCCTCATTGT TCTTAAGAAT5881ATATGGGATT GTATTGGGAC TAAGTAGTCT GATCCACTGA AGCTGAATAT TAATGGCCAT5941GACCACCCTT GGGTATTTTT ATGGGAGGCA GAATTAATCT ATATATCTCA CCTTCTTTCT6001AACCTTTTCT TATGTGCTTT TACCGCCGAC CCTGGTCATT ACAGAATATT GTTGCTATGG6061TGATCTTTTG AATTTTTTGA GAAGAAAACG TGATTCATTT ATTTGTTCAA AGCAGGAAGA6121TCATGCAGAA GCTGCACTTT ATAAGAATCT TCTGCATTCA AAGGAGTCTT CCTGGTAAGA6181CTGATTTACA TAAATAGTTA GCTGTTGACA GGCAGTTCAT GGGGAACTCT TTATTCAAAC6241TTTACATGAC TTTCCTCAAA TTGGTCCAGT CTATTATGTA GCAAAGGGGA TGAGGAGGTA6301GAGCATGACC CATGAGTGCC CTTCTACATG TCCCACTTGA TTCAGTCATG ACTTGTTTCA6361TCTCTCCCAG CAGCGATAGT ACTAATGAGT ACATGGACAT GAAACCTGGA GTTTCTTATG6421TTGTCCCAAC CAAGGCCGAC AAAAGGAGAT CTGTGAGAAT AGGTCAGTAC CTACCTATCA6481AGCAACCAAG AGTAACTTTA CAGAGAGTAT GTATATCATG CTAATGTGGA ATATAACATC6541ATTCCAGTAG CAATGATGCA GACCAGTTCT GCTTTATGGT AGCAGTGCCA ATGGTCAATG6601GCAGTTAGGG GCAAGTTCAC ATTAGTTCAT TGATTACCAG CCTTTGGTAT GTCATTGCCA6661CTGTCTTTTC CTTTCCTGAC CTTTATGGTT GTAATTGCTA AGAAAAATCC TCTCTTCCTC6721ACAGGCTCAT ACATAGAAAG AGATGTGACT CCCGCCATCA TGGAGGATGA CGAGTTGGCC6781CTAGACTTAG AAGACTTGCT GAGCTTTTCT TACCAGGTGG CAAAGGGCAT GGCTTTCCTC6841GCCTCCAAGA ATGTAAGTGG GAGTGATTCT CTAAAGAGTT TTGTGTTTTG TTTTTTTGAT6901TTTTTTTTTT TTTTTTTTTT TTTTGAGAAC AGAGCATTTT AGAGCCATAG TTAAAAGCAG6961AATGTCATTT AAAACAAAAG TATTGGATTT TTTATAATAT AAGCAACACT ATAGTATTAA7021AAAGTTAGTT TTCACTCTTT ACAAGTTAAA ATGAATTTAA ATGGTTTTCT TTTCTCCTCC7081AACCTAATAG TGTATTCACA GAGACTTGGC AGCCAGAAAT ATCCTCCTTA CTCATGGTCG7141GATCACAAAG ATTTGTGATT TTGGTCTAGC CAGAGACATC AAGAATGATT CTAATTATGT7201GGTTAAAGGA AACGTGAGTA CCCATTCTCT GCTTGACAGT CCTGCAAAGG ATTTTTAGTT7261TCAACTTTCG ATAAAAATTG TTTCCGTGAC TTTCATAATG TAAATCCTGT CTAGGGATAT7321CACACATTTT AGCAGTCAAA TGTATTTCAG AGGTGATTGG GATCATCTGA GTTCATATAG7381GTAAAAGGTT TTTGTGAGAT GGTACTCAAG TTATCACTCC ACATTTCAGC AACAGCAGCA7441TCTATAAGAA TATCTTCTGT TCAATTTTGT TGAGCTTCTG AATTAACATT ATTGACTCTG7501TTGTGCTTCT ATTACAGGCT CGACTACCTG TGAAGTGGAT GGCACCTGAA AGCATTTTCA7561ACGTGTATAC ACGTTTGAAA GTGACGTCTG GTCCTATCGG ATTTTTCTTT GGGAGCTGTT7621CTCTTTAGGT AAAATGATCC TTGCCAAAAG ACAACTTCAT TAGACTCAGA GCATCTTGAA7681GTTTCATTGG TGTCCTGCTT CCTTGTGATT AACACTGCTT TGCAAACTGT GTCTCAGGAA7741GCAGCCCCTA TCCTGGAATG CCGGTCGATT CTAAGTTCTA CAAGATGATC AAGGAAGGCT7801TCCGGATGCT CAGCCTGAAC ACGCACCTGC TGAAATGTAA GAGCCAAAAA ATTTTTCCTT7861TAGGTCACGT TTTCCCTTTT ATTTTTCTTT TTAGAGACAG AAACCCAGAT GTTGAGGGTT7921TTCATAACAC AGTTTGAAAT GTCACTTCCA TTCTTTATGA CACACTGGTC AAATGTCATT7981TCTCTAGTTT ATTTTCATAA TCTCTTGTCA CCAAAAATAC AGAAAGTTTC AGTAATATTT8041CATACATGCA GTGTTTTATG TTATCTATAT GTCAGTCCAT ATGTCCAGTT GCATAGCCCT8101CGAATTATTA CTGAAGTTGC TGGATGCCCA TACATTTGAA AACAACCTCA GGGCATTGAC8161GAGGGATAGT AAATGGCCCT TGTCTTGCAG GTATCACATA ATGAAGACTT GCTGGGATGC8221AGATCCCCTA AAAAGACCAA CATTCAAGCA AATTGTTCAG CTAATTGAGA AGCAGATTTC8281AGAGACCACC AATCATGTGA GTATACCCTG CCCAGCCATA GAATCCCCCT TCTCCCAGTT8341CCAGGTGTGT CCTCCTCCTC AGGCTTTCAG GGTGAGGACT AACCTCCCAA CCCCTTCTCT8401CCTAATCTTA GGTTGCAAAT TGGGCTTCAC GTAGGGGAAG TAAAGCAATG GAAACTAGTT8461CTTTTAAGAG TTCCATCAGT TAGTTGTGAT CTTGACACTG TAAGTATGCC TTTTGTTGCT8521ATGTTCGTTG TAGGGACTGC TGTATTCACT ATGGGCTTGT TTTCTCCACA TTTACTCCAA8581CTTAGCAAAC TGCAGCCCCA ACCGACACAA GCCCGTGGTA GACCATTCTG TGCGGATCAA8641TTCTGTCGGC AGCACCGCTT CCTCCTCCCA GCCTCTGCTT GTGCACGACG ATGTCTGAGC8701ACAATCAGTG TTTGGGTCAC CCCTCCAGGA ATCATCTCTT CTTTTGGCTT CCATGATGGT8761TATTTTCTTT TCTTTCAACT TGCATCCAAC TCCAGGATAG TGGGCACCCC ACTGCAATCC8821TGTCTTTCTG AGCACACTTT AGTGGCCGAT GATTTTTGTC ATCAGCCACC ATCCTATTGC8881AAAGCTTCCA ACTGTATATA TTCCCAATAG CAACGTAGCT TCTACCATCA ACAGAAAACA8941TTCTGATTTG GAAAAAGAGA GGCAGGTATG GACTGGGGGC CAGAGTCCTT TCCAAGGCTT9001CTCCAATTCT GCCCAAAAAT ATGGTTGATA GTTTACCTGA ATAAATGGTA GTAATCACAG9061TTGGCCTTCA GAACCATCCA TAGTAGTATG ATGATACAAG ATTAGAAGCT GAAAACCTAA9121GTCCTTTATG TGGAAAACAG AACATCATTA GAACAAAGGA CAGAGTATGA ACACCTGGGC9181TTAAGAAATC TAGTATTTCA TGCTGGGAAT CAGACATAGG CCATGAAAAA AATGATCCCC9241AAGTCTGAAC AAAAGATCCT CTTCTGTCGA CCACTGCATG AGCTTTTATA CTACCGACCT9301GGTPTTTAAA TAGACTTTGC TATTAGAGCA TTGAATTGGA GAGAAGGCCT CCCTAGCCAG9361CACTTGTATA TACGCATGTA TAAATTGTCC GTGTTCATAC ATTTGAGGGG AAAACACCAT9421AAGGTTTCGT TTCTGTATAC AACCCTGGCA TTATGTCCAC TGTGTATAGA AGTAGATTAA9481GAGCCATATA AGTTTGAAGG AAACACTTAA TACCATTTTT TAAGGAAACA ATATAACCAC9541AAAGCACAGT TTGAACAAAA TCTCCTCTTT TAGCTGATGA ACTTATTCTG TAGATTCTCT9601GGAACAAGCC TATCAGCTTC AGAATGGCAT TGTACTCAAT GGATTTGATG CTGTTTGACA9661AAGTTACTGA TTCACTGCAT GGCTCCCACA GGAGTGGGAA AACACTGCCA TCTTAGTTTG9721GATTCTTATG TAGCAGGAAA TAAAGTATAG GTTTAGCCTC CTTCGCAGGC ATGTCCTGGA9781CACCGGGCCA CTATCTATAT ATGTGTATGT ACGTTTGTAT GTGTGTAGAC AAATATTTGG9841AGGGGTATTT TTGCCCTGAG TCCAAGAGGG TCCTTTAGTA CCTGAAAAGT AACTTGGCTT9901TCATTATTAG TACTGCTCTT GTTTCTTTTC ACATAGCTGT CTAGAGTAGC TTACCAGAAG9961CTTCCATAGT GGTGCAGAGG AAGTGGAAGG CATCAGTCCC TATGTATTTG CAGTTCACCT10021GCACTTAAGG CACTCTGTTA TTTAGACTCA TCTTACTGTA CCTGTTCCTT AGACCTTCCA10081TAATGCTACT GTCTCACTGA AACATTTAAA TTTTACCCTT TAGACTGTAG CCTGGATATT10141ATTCTTGTAG TTTACCTCTT TAAAAACAAA ACAAAACAAA ACAAAAAACT CCCCTTCCTC10201ACTGCCCAAT ATAAAAGGCA AATGTGTACA TGGCAGAGTT TGTGTGTTGT CTTGAAAGAT10261TCAGGTATGT TGCCTTTATG GTTTCCCCCT TCTACATTTC TTAGACTACA TTTAGAGAAC10321TGTGGCCGTT ATCTGGAAGT AACCATTTGC ACTGGAGTTC TATGCTCTCG CACCTTTCCA10381AAGTTAACAG ATTTTGGGGT TGTGTTGTCA CCCAAGAGAT TGTTGTTTGC CATACTTTGT10441CTGAAAAATT CCTTTGTGTT TCTATTGACT TCAATGATAG TAAGAAAAGT GGTTGTTAGT10501TATAGATGTC TAGGTACTTC AGGGGCACTT CATTGAGAGT TTTGTCTTGC CATACTTTGT10561CTGAAAAATT CCTTTGTGTT TCTATTGACT TCAATGATAG TAAGAAAAGT GGTTGTTAGT10621TATAGATGTC TAGGTACTTC AGGGGCACTT CATTGAGAGT TTTGTCTTGG ATATTCTTGA10681AAGTTTATAT TTTTATAATT TTTTCTTACA TCAGATGTTT CTTTGCAGTG GCTTAATGTT10741TGAAATTATT TTGTGGCTTT TTTTGTAAAT ATTGAAATGT AGCAATAATC TCTTTTGAAT10801ATTCCCAAGC CCATGAGTCC TTGAAAATAT TTTTTATATA TACAGTAACT TTATGTGTAA10861ATACATAAGC GGCGTAAGTT TAAAGGATGT TGGTGTTCCA CGTGTTTTAT TCCTGTATGT10921TGTCCAATTG TTGACAGTTC TGAAGAATTC TAATAAAATG TACATATATA AATCAAGENBANK ID: M32110VERSION M32110.1 GI:189421RATPPSPISACHSTMGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPSPGKLPKGISAGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGNVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIEPAARKQKAREAAAGIQWSEEETEDEBEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQDIVGILRDPGAQREEGRSRSEYLNRLKKQLAIYYSYGDFLLGKLMQLFPLSELVEFLBANEVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKBSKTGLVVYDSSVPTGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAFGGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMQGFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAGKTKQQLQKQQHPKKASFQKLNGISKGAQSELSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTDTQTPAVLSPSKTQATLKPKDHHQPLGRAKCVEKQQFAEQPFEKAAFQKQNDTPKGLSLPLCLPSVPAAPHQQRGRNLSPGATASCCYLRWLKTRRVAHCHCHQVGTLASVRMPSLLCIPMKFNTHFKTSGHGenHank ID: J04111VERSION J04111.1 GI:186624MTAKMETTFYDDALNASFLPSESGPYGYSNPKTLKQSNTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSGNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNFGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQNPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRNRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANNLREQVAQLKQKVMNHVNSGCQLMLTQQLQTFGENBANK ID: X59932VERSION X59932.1 GI:30255MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYFGDYTLCVSCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVNKNCWHLDAANRPSFLQLREQLEHIKTHELHLGENBANK ID: L29220VERSION L29220.1 GI:632969MHHCIRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLFYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHECHKRRTRSCSSASSMRLWGTWVKAFLARWWSAWTMPEGSLRLPGENBANK ID: M91815.1VERSION M91815.1 GI:180169HOMO SAPIENS FETAL CDNA TO MRNA.1CAGCTGACCC TGCTGGATCA CCTCGCCTTC AAGAAGATTC CTTATGAGGA GTTCTTCGGA61CAAGGATGGA TGAAACTGGA AAAGAATGAA AGGACCCCTT ATATCATGAA AACCACTAAG121CACTTCAATG ACATCAGTAA CTTGATTGCT TCAGAAATCA TCCGCAATGA GGACATCAAC181GCCAGGGTGA GCGCCATCGG GAAGTGGGTG GCCGTAGCTG ACATATGCCG CTGCCTCCAC241AACTACAATG CCGTACTGGA GATCACCTGC TCCATGAACC GCAGTGCAAT CTTCCGGCTC301AAAAAGACGT GGCTCAAAGT CTCTAAGCAG ACTAAAGCTT TGATTGATAA GCTCCAAAAG361CTTGTGTCAT CAGAGGGCAG ATTTAAGAAT CTCAGAGAAG CTCTGAAAAA TTGTGACCCA421CCCTGTGTCC CTTACCTGGG GATGTACCTC ACCGACCTGG CCTTCATCGA GGAGGGGACG481CCCAATTACA CGGAAGACGG CCTGGTCAAC TTCTCCAAGA TGAGGATGAT ATCCCATATT541ATGCCAGAGA TTCGCCAGTT TCAACAAACT GCCTACAAAA TAGAGCACCA AGCAAAGGTA601ACGCAATATT TACTGGACCA ATCTTTTGTA ATGGATGAAG AAAGCCTCTA CGAGTCTTCT661CTCCGAATAG AACCAAAACT CCCCACCTGA AGCTGTGCCC AGACCCAGAC CAGCTGCTCC721CGGGGACATG TGCTAGAIGA TACTGTACAT ATTCGTTTGG TTTCACTGGA TTTTCTTCTT781CAGTATGTGC TTCTCCAAGA AATACAAATC GTCCTTGTTC TTAGATTCCT GTAGGENBANK ID: M26708VERSION M26708.1 GI:190695MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAFANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDDDVDTKKQKTDEDDGENBANK ID: M81757VERSION M81757.1 GI:337732MPGVTVKDVNQQEFVRALAAFLEKSGKLKVPEWVDTVKLAIHKELAPYDENWFYTRAASTARHLYLRGGAGVGSNTKIYGGRQRNGVMPSHFSRGSRSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANEKHGENBANK ID: V00568DEFINITION HUMAN MRNA ENCODING THE C-NYC ONCOGENE.VERSION V00568.1 GI:34815MPLNV FTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSFSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCNWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPRSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSEPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEIAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHNLEQLRNSCAGENBANK ID: L29219.1VERSION L29219.1 GI:632963MRHSKRTYCPDWDDKDWDYGKWRSSSSHERRERENSSAQENKRCKYNHSKMCDSHYLESRSINEEDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGREVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYIGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRACKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSIGENBANK ID: U49399.1VERSION U49399.1 GI:1418220MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPLGENBANK ID: XM_039993.2VERSION XM_039993.2 GI:16188964MVSYWDTGVLLCALLSCLLLTGSSS0SKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVN0HLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTNSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKNFNHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMASTLVVADSRISGIYICIASNKVQTVGRNISFYITDVPNGFHVNLEKNPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAIESSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLTLFIRKDAKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEFKKEKNEPGLEQGKKPRLDSVTSSESFASSGFQEDKSLSDVEEEEDSD0FYKEPITMEDLISYSFQVARQNEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSFYPGVQNDEDFCSRLREGNRMRAPEYSTFEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNSVVLYSTPPIGENBANK ID: U61262.1VERSION U61262.1 GI:1621606CDS 137..4522/CODON_START=11GGGCCGGGCC GGGCTGGGCT GGAGCAGCGG CGCCCGGGAG CCGAGCTTGC AGCGAGGGAC61CGGCTGAGGC GCGCGGGAGG GAAGGAGGCA ACGGCTCCGC GGCGCTGTCG CGCTGCCGCT121CACTCTCGGG GAAGAGATGG CGGCGGAGCG GGGAGCCCGG CGACTCCTCA GCACCCCCTC181CTTCTGGCTC TACTGCCTGC TGCTGCTCGG GCGCCGGGCG CCGGGCGCCG CGGCGGCCAG241GAGCGGCTCC GCGCCGCAGT CCCCAGGAGC CAGCATTCGA ACGTTCACTC CATTTTATTT301TCTGGTGGAG CCGGTGGATA CACTCTCAGT TAGAGGCTCT TGTGTTATAT TAAACTGTTC361AGCATATTCT GAGCCTTCTC CAAAAATTGA ATGGAAAAAA GATGGAACTT TTTTAAACTT421AGTATCAGAT GATCGACGCC AGCTTCTCCC GGATGGATCT TTATTTATCA GCAATGTGGT481GCATTCCAAA CACAATAAAC CTGATGAAGG TTATTATCAG TGTGTGGCCA CTGTTGAGAG541TCTTGGAACT ATTATCAGTA GAACAGCGAA CCTCATAGTA GCAGGTCTTC CAAGATTTAC601CAGCCAACCA GAACCTTCCT CAGTTTATGC TGGGAACGGA GCAATTCTGA ATTGTGAAGT661TAATGCAGAT TTGGTCCCAT TTGTGAGGTG GGAACAGAAC AGACAACCCC TTCTTCTGGA721TGATAGAGTT ATCAAACTTC CAAGTGGAAT GCTGGTTATC AGCAATGCAA CTGAAGGAGA781TGGCGGGCTT TATCGCTGCG TAGTGGAAAG TGGTGGGCCA CCAAAGTATA GTCATGAAGT841TGAATTGAAG GTTCTTCCAG ATCCTGAGGT GATATGAGAC TTGGTATTTT TGAAACAGCC901TTCTCCCTTA GTCAGAGTCA TTGGTCACGA TGTAGTGTTG CCATGTGTTG CTTCAGGACT961TCCTACTCCA ACCATTAAAT GGATGAAAAA TGAGGAGGCA CTTGACACAC AAAGCTCTGA1021AAGATTGGTA TTGCTGGCAG GTGGTAGCCT GGAGATCAGT GATGTTACTG AGGATGATGC1081TGGGACTTAT TTTTGTATAG CTGATAATGG AAATGAGACA ATTGAAGCTC AAGCAGAGCT1141TACAGTGCAA GCTCAACCTG AATTCCTGAA GCAGCCTACT AATATATATG CTCACGAATC1201TATGGATATT GTATTTGAAT GTGAAGTGAC TGGAAAACCA ACTCCAACTG TGAAGTGGGT1261CAAAAATGGG GATATGGTTA TCCCAAGTGA TTATTTTAAG ATTGTAAAGG AACATAATCT1321TCAAGTTTTG GGTCTGGTGA AATCAGATGA AGGGTTCTAT CAGTGCATTG CTGAAAATGA1381TGTTGGAAAT GCACAAGCTG GAGCCCAACT GATAATCCTT GAACATGCAC CAGCCACAAC1441GGGACCACTG CCTTCAGCTC CTCGGGATGT CGTGGCCTCC CTGGTCTCTA CCCGCTTCAT1501CAAATTGACG TGGCGGACAC CTGCATCAGA TCCTCACGGA GACAACCTTA CCTACTCTGT1561GTTCTACACC AAGGAAGGGA TTGCTAGGGA ACGTGTTGAG AATACCAGTC ACCCAGGAGA1621GATGCAAGTA ACCATTCAAA ACCTAATGCC AGCGACCGTG TACATCTTTA GAGTTATGGC1681TCAAAATAAG CATGGCTCAG GAGAGAGTTC AGCTCCACTG CGAGTAGAAA CACAACCTGA1741GGTTCAGCTC CCTGGCCCAG CACCTAACCT TCGTGCATAT GCAGCTTCGC CTACCTCCAT1801CACTGTTACG TGGGAAACAC CAGTGTCTGG CAATGGGGAA ATTCAGAATT ATAAGTTGTA1861CTACATGGAA AAGGGGACTG ATAAAGAACA GGATGTTGAT GTTTCAAGTC ACTCTTACAC1921CATTAATGGG TTGAAAAAAT ATACAGAGTA TAGTTTCCGA GTGGTGGCCT ACAATAAACA1981TGGTCCTGGA GTTTCCACAC CAGATGTTGC TGTTCGAACA TTGTCAGATG TTCCCAGTGC2041TGCTCCTCAG AATCTGTCCT TGGAAGTGAG AAATTCAAAG AGTATTATGA TTCACTGGCA2101GCCACCTGCT CCAGCCACAC AAAATGGGCA GATTACTGGC TACAAGATTC GCTACCGAAA2161GGCCTCCCGA AAGAGTGATG TCACTGAGAC CTTGGTAAGC GGGACACAGC TGTCTCAGCT2221GATTGAAGGT CTTGATCGGG GGACTGAGTA TAATTTCCGA GTGGCTGCTC TAACAATCAA2281TGGTACAGGC CCGGCAACTG ACTGGCTGTC TGCTGAAACT TTTGAAAGTG ACCTAGATGA2341AACTCGTGTT CCTGAAGTGC CTAGCTCTCT TCACGTACGC CCGCTCGTTA CTAGCATCGT2401AGTGAGCTGG ACTCCTCCAG AGAATCAGAA CATTGTGGTC AGAGGTTACG CCATTGGTTA2461TGGCATTGGC AGCCCTCATG CCCAGACCAT CAAAGTGGAC TATAAACAGC GGTATTACAC2521CATTGAAAAT CTGGATCCCA GCTCTCACTA TGTGATTACC CTGAAAGCAT TTAATAACGT2581GGGTGAAGGC ATCCCCCTGT ATGAGAGTGC TGTGACCAGG CCTCACACAG ACACTTCTGA2641AGTTGATTTA TTTGTTATTA ATGCTCCATA CACTCCAGTG CCAGATCCCA CTCCCATGAT2701GCCACCACTG GGAGTTCAGG CTTCCATTCT GAGTCATGAC ACCATCAGGA TTACGTGGGC2761AGACAACTCG CTGCCCAAGC ACCAGAAGAT TACAGACTCC CGATACTACA CCGTCCGATG2821GAAAACCAAC ATCCCAGCAA ACACCAAGTA CAAGAATGCA AATGCAACCA CTTTGAGTTA2881TTTGGTGACT GGTTTAAAGC CGAATACACT CTATGAATTC TCTGTGATGG TGACCAAAGG2941TCGAAGATCA AGTACATGGA GTATGACAGC CCATGGGACC ACCTTTGAAT TAGTTCCGAC3001TTCTCCACCC AAGGATGTGA CTGTTGTGAG TAAAGAGGGG AAACCTAAGA CCATAATTGT3061GAATTGGCAG CCTCCCTCTG AAGCCAATGG CAAAATTACA GGTTACATCA TATATTACAG3121TACAGATGTG AATGCAGAGA TACATGACTG GGTTATTGAG CCTGTTGTGG GAAACAGACT3181GACTGACCAG ATACAAGAGT TAACTCTTGA CACACCATAC TACTTCAAAA TCCAGGCACG3241GAACTCAAAG GGCATGGGAC CCATGTCTGA AGCTGTCCAA TTCAGAACAC CTAAAGCGGA3301CTCCTCTGAT AAAATGCCTA ATGATCAAGC CTCAGGGTCT GGAGGGAAAG GAAGCCGGCT3361GCCAGACCTA GGATCCGACT ACAAACCTCC AATGAGCGGC AGTAACAGCC CTCATGGGAG3421CCCCACCTCT CCTCTGGACA GTAATATGCT GCTGGTCATA ATTGTTTCTG TTGGCGTCAT3481CACCATCGTG GTGGTTGTGA TTATCGCTGT CTTTTGTACC CGTCGTACCA CCTCTCACCA3541GAAAAAGAAA CGAGCTGCCT GCAAATCAGT GAATGGCTCT CATAAGTACA AAGGGAATTC3601CAAAGATGTG AAACCTCCAG ATCTCTGGAT CCATCATGAG AGACTGGAGC TGAAACCCAT3661TGATAAGTCT CCAGACCCAA ACCCCATCAT GACTGATACT CCAATTCCTC GCAACTCTCA3721ACATATCACA CCAGTTGACA ACTCCATCCA CAGCAATATC CATCAAAGGC GAAATTCATA3781CAGAGGGCAT GAGTCAGAGG ACAGCATGTC TACACTGGCT GGAAGGCGAG GAATGAGACC3841AAAAATGATG ATGCCCTTTG ACTCCCAGCC ACCCCAGCCT GTGATTAGTG CCCATCCCAT3901CCATTCCCTC GATAACCCTC ACCATCATTT CCACTCCAGC AGCCTCGCTT CTCCAGCTCG3961CAGTCATCTC TACCACCCGG GCAGCCCATG GCCCATTGGC ACATCCATGT CCCTTTCAGA4021CAGGGCCAAT TCCACAGAAT CCGTTCGAAA TACCCCCAGC ACTGACACCA TGCCAGCCTC4081TTCCTCTCAA ACATGCTGCA CTGATCACCA GGACCCTGAA GGTGCTACCA GCTCCTCTTA4141CTTGGCCAGC TCCCAAGAGG AAGATTCAGG CCAGACTCTT CCCACTGCCC ATGTTCGCCC4201TTCCCACCCA TTGAAGAGCT TCGCCGTGCC AGCAATCCCG CCTCCAGGAC CTCCCACCTA4261TGATCCTGCA TTGCCAAGCA CACCATTACT GTCCCAGCAA GCTCTGAACC ATCACATTCA4321CTCAGTGAAG ACAGCCTCCA TCGGGACTCT AGGAAGCAGC CCCCCTCCTA TGCCAGTGGT4381TGTTCCCAGT GCCCCTGAAC TGCAGGAGAC CACAAGGATG TTGGAAGACT CCGAGAGTAG4441CTATGAACCA GATGAGCTGA CCAAAGAGAT GGCCCACCTG GAAGGACTAA TGAAGGACCT4501AAACGCTATC ACAACAGCAT GACGACCTTC ACCAGGACCT GACTTCAAAC CTGAGTCTGG4561AAGTCTTGGA ACTTAACCCT TGAAAACAAG GAATTGTACA GAGTACGAGA GGACAGCACT4621TGAGAACACA GAATGAGCCA GCAGACTGGC CAGCGCCTCT GTGTAGGGCT GGCTCCAGGC4681ATGGCCACCT GCCTTCCCCT GGTCAGCCTG GAAGAAGCCT GTGTCGAGGC AGCTTCCCTT4741TGCCTGCTGA TATTCTGCAG GACTGGGCAC CATGGGCCAA AATTTTGTGT CCAGGGAAGA4801GGCCAGAAGT GCAACCTGCA TTTCACTTTG TGGTCAGGCC GTGTCTTTGT GCTGTGACTG4861CATCACCTTT ATGGAGTGTA GACATTGGCA TTTATGTACA ATTTTATTTG TGTCTTATTT4921TATTTTACCT TCAAAAACAA AAACGCCATC CAAAACCAAG GAAGTCCTTG GTGTTCTCCA4981CAAGTGGTTG ACATTTGACT GCTTGTTCCA ATTATGTATG GAAAGTCTTT GACACTGTGG5041GTCGTTCCTG GGGTTGGCTT GTTTTTTGGT TTCATTTTTA TTTTTTAATT CTGAGTCATT5101GCATCCTCTA CCAGCTGTTA ATCCATCACT CTGAGGGGGA GGAAATGTTG CATTGCTGTT5161TGTAAGCTTT TTTTATTATT TTTTTATTAT AATTATTAAA GGCCTGACTC TTTCCTCTCA5221TCACTGTGAG ATTACAGATC TATTTGAATT GAATGAAATG TAACATTGAA AAAAAAAAAA5281AAAAAAAAAA AAAAAAAGENBANK ID: M11730.1VERSION M11730.1 GI:183986PRODUCT=“HER2 MRNA”CDS 151..3918/CODON_START=11AATTCTCGAG CTCGTCGACC GGTCGACGAG CTCGAGGGTC GACGAGCTCG AGGGCGCGCG61CCCGGCCCCC ACCCCTCGCA GCACCCCGCG CCCCGCGCCC TCCCAGCCGG GTCCAGCCGG121AGCCATGGGG CCGGAGCCGC AGTGAGCACC ATGGAGCTGG CGGCCTTGTG CCGCTGGGGG181CTCCTCCTCG CCCTCTTGCC CCCCGGAGCC GCGAGCACCC AAGTGTGCAC CGGCACAGAC241ATGAAGCTGC GGCTCCCTGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC301CAGGGCTGCC AGGTGGTGCA GGGAAACCTG GAACTCACCT ACCTGCCCAC CAATGCCAGC361CTGTCCTTCC TGCAGGATAT CCAGGAGGTG CAGGGCTACG TGCTCATCGC TCACAACCAA421GTGAGGCAGG TCCCACTGCA GAGGCTGCGG ATTGTGCGAG GCACCCAGCT CTTTGAGGAC481AACTATGCCC TGGCCGTGCT AGACAATGGA GACCCGCTGA ACAATACCAC CCCTGTCACA541GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG CAGCTTCGAA GCCTCACAGA GATCTTGAAA601GGAGGGGTCT TGATCCAGCG GAACCCCCAG CTCTGCTACC AGGACACCAT TTTGTGGAAG661GACATCTTCC ACAAGAACAA CCAGCTGGCT CTCACACTGA TAGACACCAA CCGCTCTCGG721GCCTGCCACC CCTGTTCTCC GATGTGTAAG GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG781GATTGTCAGA GCCTGACGCG CACTGTCTGT GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA841CTGCCCACTG ACTGCTGCCA TGAGCAGTGT GCTGCCGGCT GCACGGGCCC CAAGCACTCT901GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC961CTGGTCACCT ACAACACAGA CACGTTTGAG TCCATGCCCA ATCCCGAGGG CCGGTATACA1021TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TTTCTACGGA CGTGGGATCC1081TGCACCCTCG TCTGCCCCCT GCACAACCAA GAGGTGACAG CAGAGGATGG AACACAGCGG1141TGTGAGAAGT GCAGCAAGCC CTGTGCCCGA GTGTGCTATG GTCTGGGCAT GGAGCACTTG1201CGAGAGGTGA GGGCAGTTAC CAGTGCCAAT ATCCAGGAGT TTGCTGGCTG CAAGAAGATC1281TTTGGGAGCC TGGCATTTCT GCCGGAGAGC TTTGATGGGG ACCCAGCCTC CAACACTGCC1321CCGCTCCAGC CAGAGCAGCT CCAAGTGTTT GAGACTCTGG AAGAGATCAC AGGTTACCTA1381TACATCTCAG CATGGCCGGA CAGCCTGCCT GACCTCAGCG TCTTCCAGAA CCTGCAAGTA1441ATCCGGGGAC GAATTCTGCA CAATGGCGCC TACTCGCTGA CCCTGCAAGG GCTGGGCATC1501AGCTGGCTGG GGCTGCGCTC ACTGAGGGAA CTGGGCAGTG GACTGGCCCT CATCCACCAT1561AACACCCACC TCTGCTTCGT GCACACGGTG CCCTGGGACC AGCTCTTTCG GAACCCGCAC1621CAAGCTCTGC TCCACACTGC CAACCGGCCA GAGGACGAGT GTGTGGGCGA GGGCCTGGCC1681TGCCACCAGC TGTGCGCCCG AGGGCACTGC TGGGGTCCAG GGCCCACCCA GTGTGTCAAC1741TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGACTACT GCAGGGGCTC1801CCCAGGGAGT ATCTGAATGC CAGGCACTGT TTGCCCTGCC ACCCTGACTG TCAGCCCCAG1861AATGGCTCAG TGACCTGTTT TGGACCGGAG GCTGACCAGT GTGTGGCCTC TCCCCACTAT1921AAGGACCCTC CCTTCTGCGT GGCCCGCTGC CCCAGCGGTG TGAAACCTGA CCTCTCCTAC1981ATGCCCATCT GGAAGTTTCC AGATGACGAG GGCGCATGCC AGCCTTGCCC CATCAACTGC2041ACGCACTCCT GTGTGGACCT GGATGACAAG GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT2101CTGACGTCCA TCGTCTCTGC GGTGCTTGGC ATTCTGCTGG TCGTGGTCTT GGGGGTGGTC2161TTTGGGATCC TCATCAAGCG ACGGCAGCAG AAGATCCCCA ACTACACCAT CCGGACACTG2221CTGCAGCAAA CGGAGCTGGT GGAGCCCCTG ACACCTAGCG GAGCGATGCC CAACCAGGCG2281CAGATGCGCA TCCTGAAAGA GACGGAGCTG ACGAAGGTGA AGGTGCTTGG ATCTGGCGCT2341TTTGGCACAG TCTACAAGCG CATCTGGATC CCTGATCGGC ACAATGTGAA AATTCCAGTG2401GCCATCAAAG TGTTGAGGGA AAACACATCC CCCAAAGCCA ACAAAGAAAT CTTACACGAA2461GCATACGTGA TGGCTGGTGT GGGCTCCCCA TATGTCTCCC GCCTTCTGGG CATCTCCCTC2521ACATCCACGG TGCAGCTGGT GACACAGCTT ATGCCCTATG GCTGCCTCTT ACACCATGTC2581CGGGAAAACC GCGGACGCCT CGGCTCCCAG GACCTGCTGA ACTGGTGTAT GCAGATTGCC2641AAGGGGATGA GCTACCTGGA GGATGTGCGC CTCCTACACA CGGACTTAGC CGCTCGGAAC2701GTCCTGGTCA AGAGTCCCAA CCATGTCAAA ATTACAGACT TCGGGCTGGC TCGGCTGCTG2761GACATTGACG AGACAGAGTA CCATGCAGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG2821CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CACCAGAGTG ATGTGTGGAG TTATGGTGTG2881ACTGTGTGGG AGCTGATGAC TTTTGGGGCC AAACCTTACG ATGGGATCCC AGCCCGGGAG2941ATCCCTGACC TGCTCGAAAA GGGGGAGCGG CTGCCCCAGC CCCCCATCTG CACCATTGAT3001GTCTACATGA TCATGGTCAA ATGTTGGATG ATTGACTCTG AATGTCGGCC AAGATTCCGG3061GAGTTGGTGT CTGAATTCTC CCGCATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG3121AATGAGGACT TGGGCCCAGC CAGTCCCTTG GACAGCACCT TCTACCGCTC ACTGCTGGAG3181GACGATGACA TGGGGGACCT GGTGGATGCT GAGGAGTATC TGGTACCCCA GCAGGGCTTC3241TTCTGTCCAG ACCCTGCCCC GCGCGCTGGG GGCATGGTCC ACCACAGGCA CCGCAGCTCA3301TCTACCAGGA GTGGCGGTGG GGACCTGACA CTAGGGCTGG AGCCCTCTGA AGAGGAGGCC3361CCCAGGTCTC CACTGGCACC CTCCGAAGGG GCTGGCTCCG ATGTATTTGA TGGTGACCTG3421GGAATGGGGG CAGCCAAGGG GCTGCAAAGC CTCCCCACAC ATGACGCCAG CCCTCTACAG3481CGGTACAGTG AGGACCCCAC AGTACCCCTG CCCTCTGAGA CTGATGGCTA CGTTGCCCCC3541CTGACCTGCA GCCCCCAGCC TGAATATGTG AACCAGCCAG ATGTTCGGCC CCAGCCCCCT3601TCGCCCCGAG AGGGCCCTCT GCCTGCTGCC CGACCTGCTG GTGCCACTCT GGAAAGGGCC3661AAGACTCTCT CCCCAGGGAA GAATGGGGTC GTCAAAGACG TTTTTGCCTT TGGGGGTGCC3721GTGGAGAACC CCGAGTACTT GACACCCCAG GGAGGAGCTG CCCCTCAGCC CCACCCTCCT3781CCTGCCTTCA GCCCAGCCTT CGACAACCTC TATTACTCGG ACCAGGACCC ACCAGAGCGG3841GGGGCTCCAC CCAGCACCTT CAAAGGGACA CCTACGGCAG AGAACCCAGA GTACCTGGGT3901CTGGACGTGC CAGTGTGAAC CAGAAGGCCA AGTCCGCAGA AGCCCTGATC TGTCCTCAGG3961GAGCAGGGAA GGCCTGACTT CTGCTGGCAT CAAGAGGTGG GAGGGCCCTC CGACCACTTC4021CAGGGGAACC TGCCATGCCA GGAACCTGTC CTAAGGAACC TTCCTTCCTG CTTGAGTTCC4081CAGATGGCTG GAAGGGGTCC AGCCTCGTTG GAAGAGGAAC AGCACTGGGG AGTCTTTGTG4141GATTCTGAGG CCCTGCCCAA TGAGACTCTA GGGTCCAGTG GATGCCACAG CCCAGCTTGG4201CCCTTTCCTT CCAGATCCTG GCTACTGAAA GCCTTAGGGA AGCTGGCCTG AGAGGGGAAG4261CGGCCCTAAG GGAGTGTCTA AGAACAAAAG CGACCCATTC AGAGACTGTC CCTGAAACCT4321AGTACTGCCC CCCATGAGGA AGGAACAGCA ATGGTGTCAG TATCCAGGCT TTGTACAGAG4381TGCTTTTCTG TTTAGTTTTT ACTTTTTTTG TTTTGTTTTT TTAAACACGA AATAAAGACC4441CAGGGGAGAA TGGGTGTTGT ATGGGGAGGC AAGTGTGGGG GGTCCTTCTC CACACCCACT4501TTGTCCATTT GCAAATATAT TTTGGAAAACGENBANK ID: X14798.1SEQUENCE 1:MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIFKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCGLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYFESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTFDNNCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDBVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHANLDVKPDADESEQUENCE 2;MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDFRQWTETHVRDWVNWAVNEFSLKGVDFQKFCMNGAALCALGKDGFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDDLQTDTLQNDYFAIKQEVVTPDNMCNGRTSRGSGPIQLWQFLLELLTDKSCQSFTSWTGDGWEFKLSDPDEVARRNGKRRNKPKNNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADEGENBANK ID: D49547VERSION D49547.1 GI:710654MGKDYYQTLGLARGASDEEIKRAYRRQALRYNFDKNKEFGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGSGPSGCSGGGANGTSFSYTFHGDPRAMFAEFFGGRNPFDTFFGQRNGEEGNDIDDFFSGFPMGMGGFTNVNFGRSRSAQEPARKKQDPPVTNDLRVSLEEIYSGCTKKMKISHKRLNFDGKSIRNEDKILTIEVKKGWKEGTKITEPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIFVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPIGENBANK ID: M11717VERSION D49547.1 GI:710654MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGSGPSCGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGNDIDDPFSGFPNGNGGFTNVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIFADIVFVLKDKPHNIFKRDGSDVIYFARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGNRRKVPGEGLFLFKTFEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPIGENBANK ID: X76648VERSION X76648.1 GI:531404MAQSFVNCKIQFGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVFRVFIGKDCIGGCSDLVSLQQSGSLLTRLKQIGALQGENBANK ID: NM_011587.1VERSION NM_011587.1 GI:6755784MVWWGSSLLLFTLFLASHVGASVDLTLLANLRITDPQRFFLTCVSGEAGAGRSSDPPLLLSKDDRIVRTIFPGQPLYLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVLYVHNSPGAHLFPDKVTHTVNKGDTAVLSAHVHKEKQTDVIWKNNGSYFNTLDWQEADDGRFQLQLQNVQPPSSGIYSATYLSASFLGSAFFRLIVRGCGAGRWGPGCVKDCFGCLHGGVCMDMDGSCVCPPGFTGTRQSQACRSGRFGQSCQSQCPGTAGCRGLTFCLPDPYGCSCGSGWRGSQCQSACAPDHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILSMATSVSFNIGTMPRINCAAAGNPFPVRGSMKLRKPDGTMLLSTKVIVEPDRTTASFSVFSLTLGDSGFWECRVSTSGGQDSRRFKVNVKVPPVPLTAPRLLAKQSRQLVVSPLVSFSGDGPISSVRLEYRPQDSTIAWSAIVVDPSSNVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGPSALMTTDCPEPLLQFWLSSWNVEGPDRLRVSWSLPSVPLSGDGFLLRLMDGARGQSRRSNISFPQARTALLTGLTPGTHYQLDVRLYHCTLLGPASPPAMVNLPPSGPPAPRELHAQALSDSEIQLMWQHPSAPSGPISKYIVSIQVAGGSGDFQWMDVDRPESTSIIVRGLNASTRYLFRVRASVQGLGDWSNTVSSATLGNGLQSEDPVRESRAASEGLDQQLVLAVVGSVSATCLTILAALLALVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRFKFQFSPLSYFVLEWEDITFSDLIGSGNFGQVIRAMIKKDGLKMNAAIKNLKEYASENDMRDFAGELEVLCKLGBHFNIINLLGACSNRGYLYIAIEYAPYGNLLDFLRKSRVLSTDPAFARSHGTASTLSSRQLLRFASDAANGMQYLSSKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTNGRLPVRWMAISSLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYSLMRQCWRDRRYERPPFAQIALQLGRMLSARKAYVNMSLFENFTYAGIDATASSAGENBANK ID: NM_002867.1VERSION NM_002867.1 GI:4506368MASVTDGKMGVKDASDQNFDYMFKLLIIGNSSVGKTSFLLRYADDTFTPAFVSTVGIDFKVKTVYRMSKRVKLQIWDTAGQSRYRTITTAYYRGANGFILMYDITNESSFNAVQDWATQIKTYSNDNAQVILVGNKCDMEEERVVPTSKGQLLASQLGFDFFEASAKENISVRQAFSRLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTPPLLQQNCSCGENBANK ID: 027361NO VERSION DATALNENQRLAVERILSGDCRPLPYILEQPPGTQKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIVLAQDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGANNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRQSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPSGENBANK ID: NM_002752.1VERSION NM_002752.1 GI:4506096MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGISVAVIKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQMNKVIEDLGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSAQMQQGENBANK ID: M22262.1VERSION M22382.1 GI:190126MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGF0DNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKQKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVCGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMFGENBANK ID: U09564.1DEFINITION HUMAN SERINE KINASE MRNA, COMPLETE CDS.VERSION U09564.1 GI:507212MERKVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQEEEILGSDDDEQEDPNDYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSNYQGLPLPCVKKIIQQVLQGLDVLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATENQRSGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQKRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEINCNGVIEVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSLPNGDSSTSQETDSCTPITSEVSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLVNPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACMAFELATGDYLFEPNSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKNITKLKPNGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNSGENBANK ID: M11507.1VERSION M11507.1 GI:239515MMDQARSAFSNLFGGEPLSYTRFSLARQVDGDNSHVEMKLAVDEEENADNNTKANVTKPKRCSGSICYGTIAVIVFFLIGFMIGYLGYCKGVEPKTECERLAGTESPVREEPGEDFPAARRLVWDDLKRKLSEKLDSTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKIQVKDSAQNSVIIVDKNGRLVYLVENPGGYVAYSKAATVTGKLVHANFGTKKDFEDLYTPVNGSIVIVRAGKITFAEKVANAESLNAIGVLIYMDQTKFPIVNAELSFFGHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIFVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQNFSDMVLKDGFQPSRSIIFASWSAGDFGSVGATENLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTMQNVKHPVTGQFLYQDSNNASKVEKLTLDNAAFPFLAYSGIPAVSFCFCEDTDYPYLGTTMDTYKELIERIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQYRADTKEMGLSLQWLYSARCDFFRATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLSFYVSPKESPFRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFRNQLALATWTIQGAANALSGDVWDIDNEFGENBANK ID: 055017.1VERSION 055017.1 GI:1297296MESYHKFDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDIRFVLSKGHAAPILYAVWAEAGFLEAELLNLRKISSDLDGNPVFKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQNQNDIYQKRCEAFGWHAIIVDGHSVEELCKAFCQAKHQFTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATFPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNNVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKCRILTVEDHYYEGGIGEAVSSAVVGEFGITVTNLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKAGENEANK ID: X14034.VERSION X14034.1 GI:35513MSTTVNVDSLAEYEKSQIKRALELGTVNTVFSFRKSTFERRTVQVIMETRQVAWSKTADKIEGFLDINEIKEIRPGKNSKDFEPAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLNFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQENWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSTWDEKYDAVDNQDMNNPLSHYWISSSNNTYLTGDQLRSESSPEAYIRCLRNGCRCIELDCWDGPDGKFVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKNKKLGFPQDVDVNMEDKKDEHKQQGELYMWDSIDQKNTRHYCAIADAKLSFSDDIEQTNEEEVFQDIFFTELNFGEKWFHKKVEKRTSAEKLLQEYCNETGGKDGTFLVRESETFPNDYTLSFWRSGRVQNCRIRSTNEGGTLKYYLTDNLRFRRNYALIQHYRETHLPCAEFELRLTDFVFNPNPHESKPWYYDSLSRGEAEDMLNRIPRDGAFLIRKRECSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKNRLRYFVTPELLERYNTERDINSLYDVSRNYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGNWKGDYGTRIQQYFFSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAFQGKNQKSFVFILEPKEQ0DPPVEFATDRVEELFEWFQSIREITWKIDSKENNMKYWEKNQSIAIELSDLVVYCKFTSKTKDNLENPDFREIRSFVETKADSIIRQKPVDLLKYNQKGLTRVYFKQQRVDSSNYDPFRLNLCGSQNVALNFQTADKYNQNNRALFSLNGRTGYVLQFESNRTEKYDPNFFESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYGNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDFNLAFLRFVVYEEDNFSDPNFLAHATYPIKAVKSGPRSVFLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENHSSCTRRNATRGGENBANK ID: M27691.1IVERSION 1627691.1 GI:181038NTMESGAENQQSCDAAVTEAENQQNTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHCVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRFSYRKILNDLSSDAFGVPRIEEEKSEEETSAFAITTVTVFTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTNTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSDGENBANK ID: 1618391VERSION 1618391.1 GI:339716MERRWPLGLGLVLLLCAPLPPGARAKEVTTJIVIDTSKAQGELGWLLDFPKDGWSEQQQILNGTPLYNYQDCPNQGRRDTDNWLRSNWIYRCEEASRVRVELQFTVRDCKSFPGGAGFLGCKETFNLLYNESDQDVCIQLRRPLFQKVTTVAADQSFTIRDLASGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVACTCLPHARASPRFSCAPRNHCSPDGEWLVPVGRCHCEFGYEEGGSGEACVACPSGSYRNDMDTPHCLTCFQQSTAESEGATICTCESGHYRAFGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQCTAQDGGPCQPCGVGVHFSPGARALTTPAVEVNGLEFYANYTFNVEAQNGVSGLGSSGHASTSVSISMGNAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEERYQNVLEFRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDNEFRTSPFVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRHVTAPPNWIERTSCAEALCGTSRHTRTLHREPWTLPCGWSNFPSRELDFAWLNVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGCQWWNFLREATIMGQFSNFHILHLECVVTKRKPIMIITEFNENAALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVNRDLAARNILVNQNLCCKVSDFCLTRLLDDFDGTYETQGGKIPIRWTAPEAIANRIFTTASDVWSFGIVNWEVLSFGDKPYGENSNQEVNKSIEDCYRLPPPVDCPAPLYELMKNCWAYDRARRPNFQKLQAHLEQLLANPNSLRTIANFDPRVTLRLPSLSGSDGIFVRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQNGITLPGHQKRILCSIQGFKDGENBANK ID: X54079.1VERSION X54079.1 GI:32477MTERRVPFSLLRGPSWDPERDWYPHSDLFDQAFGLPRLEEWSQWLGGSSWFGYVRPLPFAAIESPAVAAFAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAFDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLFPGVDPTQVSSSLSFEGTLTVEAPMPKLATQSNEITTPVTFESRAQLGGPEAAKSDETAAKGENBANK ID: XM_012654.3VERSION XM_012654.3 GI:14773503MFGVTLWEMFSGGEEPWACVPPYLILQRLEDFARLPRPPLCSRALYSLALDCWAPHPSDRPSFSHLEGLLQEAGPSEACCVRDVTEFGALRNETGDPITVIEGSSSFHSPDSTIWKGQNGRTFKVGSWPASAVTLADAGGLPATRPVHRGHPCFGRSTPRKHRWRQKEGKSLGCAFSTGPEEEHAPGEDERNFQESGVSSVPRSSSHRGXVQAPLKXRQARAXAPGTSRFASTPTFILGENBANK ID: XM_054457.2VERSION XM_054457.2 GI:18590931MASATDSRYGQKESSDQNFDYNFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGANGFILMYDITNEESFNAVGDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLSDQQVFPHQDCACGENBANK ID: XM_038595.3VERSION XM_038595.3 GI:18590923MAPPSEETPLIPQRSCSLLSTEAGALEVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHLFADHRSDLVSGRLFVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRFHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPFTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLWSQVSYRHLVLLHGVCMAGDSTWVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLFHGNVSARKVLLAREGADGSPPFIKLSDFGVSFAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLFAPKWTELALLIQQCMAYEFVQRPSFRAVIRDLNSLISSDYELLSDFTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISGLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRGSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGFQLDMLWSGSRGCETHAFTAHFEGKHHSLSFSGENBANK ID: NM_002755.2VERSION NM_002755.2 GI:14589898MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDGFEKISELGAGNGGVVFKVSHKPSGLVMARKLTHLEIKPAIRNQIIRELQVLHECNSFYIVGFYGAFYSDGEISICMEENDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKNKIMNRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSFERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPFDAKELELMFGCQVEGDAAETPPRFRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPFPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVRAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGVGENBANK ID: NM_001744.1VERSION NM_001744.1 GI:4502556MLKVTVFSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKQTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETFTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKFENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCCFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLCSASSSHGSIQESRKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVEDGIKVADLELEECLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEYGENBANK ID: XM_053461.2VERSION XM_053461.2 GI:13553657MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTGAAFLTQTVCLDDTTVKFEIWDTAGQERYEHSLAPMYYRGAQAAIVVYDITNEESFARAKNMVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCSNGENBANK ID: U33635.1VERSION U33635.1 GI:1016701MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDPLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLRCHIDGMPRFTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFSQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLFEPSVWWEHAGVRLFTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEECKPGYLDCLTQATPKFTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLEKLKFTPPPQPQQCMGFDKEATVFCSATGREKPTIKWERADGSSLPEWVPDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERITVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNCSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLEDLKQFLRISKSKDEKLKSQPLSIKQKVALCTQVALGMEHLSNNRFVNKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQANVALRWMSPEAILEGDFSTKSDVNASGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLFQPEGCPSKLYRLMQRCWALSPKDRPSESEIASALGDSTVDSKPGENBANK ID: XM_004559.5VERSION XM_004559.5 GI:17464405MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSNSDSTAARHSRLESSSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVIS0NEDFEGVVLKDLGPPMVARLVRFYFRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTNYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGFAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFACPNLLFSEISFISDVVNNSSPALGGTFPPAPNNPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCINAIILLLLLIIALMLWRLHWRRLLSKAERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNFPHSAPCVPNGSALLLSNPAYRLLLATYARPPRGPGFPTPAWAKPTNTQAYSGDYMEPEKPGAPLLFPPFQNSVPEYAEADIVTLQCVTGGNTYAVPALPPGAVGDGPPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKNARNDFLKEVKINSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQELSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIAGFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILNGKFTTASDVWAFGVTLWEVLMLCRAQPEGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFLAEDALNTVGENBANK ID: M28212.1VERSION M28212.1 GI:550071/GENE=“RAB6”CDS 71..697/CODON_START=11AGCTGGCTGG AGCAGGATCG GTCCGGGACG GTCICTAGGC TGAGGCGGCG GCCGCTCCTC61TAGTTCCACA ATGTCCACGC GGGGAGACTT CGCGAATCCG CTGACGAAAT TCAAGCTGGT121GTTCCTGGGG GAGCAAAGCG TTGGAAAGAC ATCTTTGATC ACCAGATTCA TGTATGACAG181TTTTGACAAC ACCTATCAGG CAACAATTGG CATTGACTTT TTATCAAAAA CTATGTACTT241GGAGGATCGA ACAGTACGAT TGCAATTATG GGACACACCA GGTCAAGAGC GGTTCAGGAG301CTTGATTCCT AGCTACATTC GTGACTCCAC TGTGGCAGTT GTTGTTTATG ATATCACAAA361TGTTAACTCA TTCCAGCAAA CTACAAAGTG GATTGATGAT GTCAGAACAG AAAGAGGAAG421TGATGTTATC ATCATGCTAG TAGGAAATAA AACAGATCTT GCTGACAAGA GGCAAGTGTC481AATTGAGGAG GGAGAGAGGA AAGCCAAAGA GCTGAATGTT ATGTTTATTG AAACTAGTGC541AAAAGCTGGA TACAATGTAA AGCAGCTCTT TCGACGTGTA GCAGCAGCTT TGCCGGGAAT601GGAAAGCACA CAGGACAGAA GCAGAGAAGA TATGATTGAC ATAAAACTGG AAAAGCCTCA661GGAGCAACCA GTCAGTGAAG GAGGCTGTTC CTGCTAATGT CCCTAGTCAT CTTCAACCTT721CTTCAGAAGC TCACTGCTTTGENBANK ID: M65066.1VERSION M65066.1 GI:307376/GENE=“PRKAR1B”CDS <1..1144/CODON_START=21GGCCTCCCCG CCCGCCTGCC CCTCGGAGGA GGACCAGAGC CTGAAGGGCT GTGAGCTGTA61CGTGCAGCTG CACGGGATCC AGCAGGTCCT CAAAGACTGT ATCGTCCACC TCTGCATCTC121CAAGCCCGAA CGCCCCATGA AGTTCCTCCG GGAGCACTTC GAGAAGCTGG AGAAGGAAGA181AAACAGGCAG ATTTTGGCGC GGCAAAAGTC AAACTCACAG TCGGACTCCC ATGATGAGGA241GGTGTCGCCC ACCCCCCCGA ACCCTGTGGT GAAGGCCCGC CGCCGGCGAG GAGGCGTGAG301TGCCGAGGTG TACACCGAGG AGGACGCCGT GTCCTACGTC AGGAAGGTGA TTCCCAAGGA361CTACAAAACC ATGACTGCGC TGGCCAAGGC CATCTCCAAG AACGTGCTCT TCGCTCACCT421GGATGACAAC GAGAGGAGTG ACATATTCGA TGCCATGTTC CCTGTCACTC ACATCGCTGG481GGAGACTGTT ATACAGCAAG GGAATGAAGG AGACAACTTC TATGTCGTTG ATCAAGGGGA541AGTGGATGTG TACGTGAACG GAGAGTGGGT GACCAACATC AGCGAGGGAG GCAGCTTCGG601GGAGCTGGCG CTCATCTACG GCACCCCCAG GGCTGCGACC GTGAAAGCCA AGACGGACCT661CAAGCTCTGG GGGATCGACC CGGACAGCTA CCGGCGCATC CTTATGGGCA GCACGCTGAG721GAAACGCAAG ATGTACGAGG AGTTCCTCAG CAAGGTCTCC ATCCTAGAGT CCCTGGAGAA781GTGGGAGCGT CTGACCGTGG CGGATCGGCT GGAGCCCGTC CAGTTTGAAG ATGGAGAGAA841AATTGTGGTC CAGGGAGAGC CTCGGGACCA CTTTTACATC ATCACGGAGG GCACCGCGTC901CGTGCTGCAG CGCCGGTCCC CCAATGAGGA CTACCTCGAG GTGGGGCGCC TGGGACCCTC961TGACTACTTC GCGGAGATTC CACTCCTCCT GAACCGGCCC CGGGCGGCCA CTGTCGTGGC1021CCGGGGGCCC CTCAAGTGTG TGAAGCTGGA CCGGCCCCGC TTCGAGCGTG TGCTGGGGCC1081CTGCTCTGAG ATCCTCAAGA GGAACATTCA GCGTTACAAC AGCTTCATCT CCCTCACCGT1141CTGAGCACAC GTCCCGCCCT GCAGCCCCAG CTCCCCAGTG TGGTGGCCGT GCCTGCTCGT1201CTGTGTCGGG GGCCCGGGAG CCGCTGTGTG AGGIGIGGCC CGGGTGGGGC TGGGTCCCGG1261CAGCGTGAGG ACTGCCCCTT CCCCGGACTC ACTTTTTGGA ATAAATGATC ACCTTCTCCA1321TTTCCAAATC AAAGGACAAG CGGACAAAAT GCATCCCAAG ATCAAGGAAG GGACAGCCCA1381GCTTCCTCCC CACACGCCTC CCCGGCTGCC TCTGTGGGCT TCTCCTGGGG GGCCCACCCC1441ACCCCTGCCA GTCTCCTGGA GATGCTTGAG GATCGGTCCT CCCCAGAAGC AGGCCAGGAC1501GTTGCCCCTG GCGGCTGGTG ACCCTGTGAG GTCAGGTCCC CCAGATTGAG GTCTGAGTGT1561GGGCAAGTGT GTCAAAAGGG GCTGCCCCCC AGGAGATGAG GCTGAGAGCA GGGAGTTGAG1621GCCGAAGAAG TCAAGGCCCC TCCCGCAAAT GTGTACCCCT GCCCGCGCCA CTGCACCCCG1681CCGCACCCCC ACCTCCCCGG GGGCCCTGCT GCGGATCGCG GACTGGGAGA GTCTCTGAGC1741TATGAGATTG ATCTTGCCCC TAATTGGAGA GGAAGCCGGG CGCCAAGACA CACGGGGCTC1801CTGCCTTGGG AGCCAGGGCC GCGGCCGCAG GTAGACCCCA GTAGGGGGGG CCGGGCTCGA1861AGTTCCTTTG GGAGGGGCTG GCCGGACTCC AGCAGGCCCT CCTCACCTTT CTTAGAAAGT1921CCACCCAGGG CAAGTTGATG TTGGGGGAAA GCAGAAGTCA AGCCAGCCGC GGCCCCACAC1981GCCCCCACCC GCTCAACCGA CTTGTCCCTT AAATGTGTCT TGGATCCCGC AGTGATGACG2041TGAGCCAGCC AGGCCCGAAA AGGTGAGGCC ACTGCAGAGA AGCTTCCCAG GGGATTCCTG2101GTTCCCCCGA AACACAAGCG AGGTCATTGC AGTTCACCCG ATGTTGCTCC TGTCCCGTGC2161GTCCCCGGGA GGCTGTCCTT GGTCCGCATG GCTCGTTGCA GCCCCTCCCC TGCTGGCGGT2221TACGATGCGT GGGGTCCCCC TCCCCACCCA GCCCCGGCAC CGTCGCCGTG TCCCGCCTGT2281GCCTGTGACG TCCCTGTGGA CCTGTGAGCC ATCCCCCCCT TATCTCTGCT CTGAATACTG2341CATGAAGCAT TAAACGTGCA ATGAAGGENBANK ID: U04897.1VERSION U04897.1 GI:451563CDS 102..1673/CODON_START=11GTTTTTTTTT TTTTTTTGGT ACCATAGAGT TGCTCTGAAA ACAGAAGATA GAGGGAGTCT61CGGAGCTCGC ATCTCCAGCG ATCTCTACAT TGGGAAAAAA CATGGAGTCA GCTCCGGCAG121CCCCCGACCC CGCCGCCAGC GAGCCAGGCA GCAGCGGCGC GGACGCGGCC GCCGGCTCCA181GGGAGACCCC GCTGAACCAG GAATCCGCCC GCAAGAGCGA GCCGCCTGCC CCGGTGCGCA241GACAGAGCTA TTCCAGCACC ACCAGAGGTA TCTCAGTAAC GAAGAAGACA CATACATCTC301AAATTGAAAT TATTCCATGC AAGATCTGTG GAGACAAATC ATCAGGAATC CATTATGGTG361TCATTACATG TGAAGGCTGC AAGGGCTTTT TCAGGAGAAG TCAGCAAAGC AATGCCACCT421ACTCCTGTCC TCGTCAGAAG AACTGTTTGA TTGATCGAAC CAGTAGAAAC CGCTGCCAAC481ACTGTCGATT ACAGAAATGC CTTGCCCTAG GGATGTCTCG AGATGCTGTA AAATTTGGCC541GAATGTCAAA AAAGCAGAGA GACAGCTTGT ATGCAGAAGT ACAGAAACAC CGGATGCAGC601AGCAGCAGCG CGACCACCAG CAGCAGCCTG GAGAGGCTGA GCCGCTGACG CCCACCTACA661ACATCTCGGC CAACGGGCTC ACGGAACTTC ACGACGACCT CAGTAACTAC ATTGACGGGC721ACACCCCTGA GGGGAGTAAG GCACACTCCG CCGTCAGCAG CTTCTACCTG GACATACAGC781CTTCCCCAGA CCAGTCAGGT CTTGATATCA ATGGAATCAA ACCAGAACCA ATATGTGACT841ACACACCAGC ATCAGGCTTC TTTCCCTACT GTTCCTTCAC CAACGGCGAG ACTTCCCCAA901CTGTGTCCAT GGCAGAATTA GAACACCTTG CACAGAATAT ATCTAAATCG CATCTGGAAA961CCTGCCAATA CTTGAGAGAA GAGCTCCAGC AGATAACGTG GCAGACCTTT TTACAGGAAG1021AAATTGAGAA CTATCAAAAC AAGCAGCGGG AGGTGATGTG GCAATTGTGT GCCATCAAAA1081TTACAGAAGC TATACAGTAT GTGGTGGAGT TTGCCAAACG CATTGATGGA TTTATGGAAC1141TGTGTCAAAA TGATCAAATT GTGCTTCTAA AAGCAGGTTC TCTAGAGGTG GTGTTTATCA1201GAATGTGCCG TGCCTTTGAC TCTCAGAACA ACACCGTGTA CTTTGATGGG AAGTATGCCA1261GCCCCGACGT CTTCAAATCC TTAGGTTGTG AAGACTTTAT TAGCTTTCTG TTTGAATTTG1321GAAAGAGTTT ATCTTCTATG CACCTGACTG AAGATGAAAT TGCATTATTT TCTGCATTTG1381TACTGATGTC AGCAGATCGC TCATGGCTGC AAGAAAAGGT AAAAATTGAA AAACTGCAAC1441AGAAAATTCA GCTAGCTCTT CAACACGTCC TACAGAAGAA TCACCGAGAA GATGGAATAC1501TAACAAAGTT AATATGCAAG GTGTCTACAT TAAGAGCCTT ATGTGGACCA CATACAGAAA1561AGCTAATGGC ATTTAAAGCA ATATACCCAG ACATTGTGCG ACTTCATTTT CCTCCATTAT1621ACAAGGAGTT GTTCACTTCA GAATTTGAGC CAGCAATGCA AATTGATGGG TAAATGTTAT1681CACCTAAGCA CTTCTAGAAT GTCTGAAGTA CAAACATGAA AAACAAACAA AAAAATTAAC1741CGAGACACTT TATATGGCCC TGCACAGACC TGGAGCGCCA CACACTGCAC ATCTTTTGGT1801GATCGGGGTC AGGCAAAGGA GGGGAAACAA TGAAAACAAA TAAAGTTGAA CTTGTTTTTC1861TCAGENBANK ID: P53667DBEST ID: 1741245EST NAME: AN07C08.S1ACTGGGCTCCCCGGTCTCCCATCGCAAGGACCTGGGTCGCTCTGAGTCCCTCCGCGTAGTCTGCCGGCCACACCGCATCTTCCGGCCGTCGTATCTCATCCACGGTGAGGTGCTGGGCAAGGGCTGCTTCGGCTATGCTATCAATGTGACATACTGTGAGACAGGTGATGTGATGGTGATGAAGGAGCTGATCCGGTTCGACGAGGAGACCCAGAGGACGTTCCTCAACGAGGTGAATGTCATTGENBANK ID: NM_002737.1VERSION NM_002737.1 GI:4506066CDS 28..20461GGAGCAAGAG GTGGTTGGGG GGGGACCATG GCTGACGTTT TCCCGGGCAA CGACTCCACG61GCGTCTCAGC ACGTGGCCAA CCGCTTCGCC CCCAAACGCG CGCTGAGGCA GAAGAACGTG121CACGAGGTGA AGGACCACAA ATTCATCGCG CGCTTCTTCA AGCAGCCCAC CTTCTCCAGC181CACTGCACCG ACTTCATCTG GGGGTTTGGG AAACAAGGCT TCCAGTGCCA AGTTTGCTGT241TTTGTGGTCC ACAAGAGCTG CCATGAATTT CTTACTTTTT CTTGTCCGGC TGCGGATAAG301GGACCCGACA CTGATGACCC CAGGAGCAAC CACAAGTTCA AAATCCACAC TTACGCAAGC361CCCACCTTCT GCGATCACTC TGGGTCACTG CTCTATGGAC TTATCCATCA AGCGATGAAA421TCTGACACCT GCGATATGAA CGTTCACAAC CAATGCGTCA TCAATGTCCC CACCGTGTGC481GCAATCGATC ACACTGAGAA GAGGGCGCGG ATTTACCTAA AGGCTGAGCT TGCTGATCAA541AAGCTCCATG TCACAGTACG ACATGCAAAA AATCTAATCC CTATGGATCC AAACGGCCTT601TCAGATCCTT ATGTGAAGCT GAAACTTATT CCTGATCCCA AGAATGAAAG CAACCAAAAA661ACCAAAACCA TCCGCTCCAC ACTAAATCCG CAGTGCAATG ACTCCTTTAC ATTCAAATTG721AAACCTTCAG ACAAAGACCG ACGACTGTCT GTACAAATCT GCGACTGCGA TCGAACAACA781AGGAATCACT TCATGGGATC CCTTTCCTTT GGAGTTTCGC ACCTGATGAA GATCCCGGCC841AGTGGATGGT ACAAGTTCCT TAACCAACAA GAACGTGAGT ACTACAACGT ACCCATTCCC901GAACGGGACG AGGAAGGAAA CATCGAACTC ACGCAGAAAT TCGAGAAACC CAAACTTCCC961CCTGCTGCCA ACAAAGTCAT CAGTCCCTCT GAAGACAGGA AACAACCTTC CAACAACCTT1021GACCGAGTGA AACTCACGGA CTTCAATTTC CTCATGGTGT TGGGAAACGC CAGTTTTCCA1081AAGGTCATGC TTGCC3ACAG GAAGGGCACA GAACAACTGT ATGCAATCAA AATCCTGAAG1141AACGATGTGG TGATTCAGCA TGATGACGTG GAGTGCACCA TGGTAGAAAA GCGACTCTTC1201GCCCTGCTTG ACAAACCCCC GTTCTTGACC CAGCTGCACT CCTCCTTCCA GACAGTGGAT2261CGGCTCTACT TCGTCATGGA ATATGTCAAC GGTGGGGACC TCATGTACCA CATTCAGCAA1321GTAGGA~AAT TTAAGGAACC ACAAGCAGTA TTCTATGCGC CAGAGATTTC CATCGGATTG1381TTCTTTCTTC ATAAAAGAGG AATCATTTAT AGGGATCTCA ACTTACATAA CGTCATGTTG1441GATTCAGAAG GACATATCAA AATTGCTGAC TTTGGGATGT GCAAGGAACA CATGATGGAT1501GGAGTCACGA CCAGGACCTT CTGTGCGACT CCACATTATA TCGCCCCAGA GATAATCCCT1561TATCAGCCGT ATGGAAAATC TGTGGACTGG TGGGCCTATC CCGTCCTGTT GTATGAAATG1621CTTGCCGCGC AGCCTCCATT TGATGGTCAA GATGAAGACG AGCTATTTCA GTCTATCATG1681GAGCACAACG TTTCCTATCC AAAATCCTTG TCCAAGCAGC CTGTTTCTAT CTGCAAAGGA1741CTGATGACCA AACACCCAGC CAAGCGCCTG GGCTGTGGGC CTGAGGGGGA GAGGGACGTG1801AGAGAGCATG CCTTCTTCCG GAGGATCGAC TGGGAAAAAC TGGAGAACAG GGAGATCGAG1861CCACCATTCA AGCCCAAAGT GTGTGGCAAA GGACCACAGA ACTTTGACAA GTTCTTCACA1921CGAGGACAGC CCGTCTTAAC ACCACCTGAT CAGCTGGTTA TTGCTAACAT AGACCAGTCT1981GATTTTGAAG GGTTCTCGTA TGTCAACCCC CAGTTTGTGC ACCCCATCTT ACAGACTGCA2041GTATGAAACT CACCAGCGAG AACAAACACC TCCCCAGCCC CCAGCCCTCC CCGCAGTGGA2101AGTGAATCCT TAACCCTAAA ATTTTAAGGC CACGGCTTGT GTCTGATTCC ATATGGAGGC2161CTGAAAATTG TAGGGTTATT AGTCCAAATG TGATCAACTG TTCAGGGTCT CTCTCTTACA2221ACCAAGAACA TTATCTTAGT GGAAGGENBANK ID: M16038.1VERSION M16038.1 GI:187268MGCIKSKGKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPESQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPWDRDANEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTNSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKNCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQPGENBANK ID: 012128.1VERSION 012128.1 GI:557287CDS 218..7690/GENE=“PTP1E”/CODON_START=11CTGATTATGA AGTGCCTCAG AGCCAACCTA TTAAGCTTGG AGATCATCTC AACAGCATAC61TGCTTGGAAT GTGTGAGGAT GTTAITTACG CTCGAGTTTC TGTICGGACT GTGCTGGATG121CTTGCAGTGC CCACATTAGG AATAGCAATT GTGCACCCTC ATTTTCCTAC GTGAAACACT181TGGTAAAACT GGTICTGGGA AATCTTTCTG GGGTAATATG CACGTGTCAC TAGCTGAGGC241CCTGGAGGTT CGGGGTGGAC CACTTCAGGA GGAAGAAATA TGGGCTGTAT TAAATCAAAG301TGCTGAAAGT CTCCAAGAAT TATTCAGAAA AGTAAGCCTA GCTGATCCTG CTGCCCTTGG361CTTCATCATT TCTCCATGGT CTCTGCTGTT GCTGCCATCT GGTAGTGTGT CATTTACAGA421TGAAAATATT TCCAATCAGG ATCTTCCAGC ATTCACTGCA CCAGAGGTTC TTCAAAATCA481GTCACTAACT TCTCTCTCAG ATGTTGAAAA GATCCACATT TATTCTCTTG GAATGACACT541GTATTGGGGG GGTGATTATG AAGTGCCTCA GAGCCAACCT ATTAAGCTTG GAGATCATCT603CAACAGCATA CTGCTTGGAA TGTGTGAGGA TGTTATTTAC GCTCGAGTTT CTGTTCGGAC661TGTGCTGGAT GCTTGCAGTG CCCACATTAG GAATAGCAAT TGTGCACCCT CATTTTCCTA721CGTGAAACAC TTGGTAAAAC TGGTTCTGGG AAATCTTTCT GCGACAGATG AGCTTTCCTG781TAACAGTGAA CAAAAGCCTG ATCGAAGCCA GGCTATTCGA GATCGATTGC GAGGAAAAGG841ATTACCAACA GGAAGAAGCT CTAGTTCTGA TGTACTAGAC ATACAAAAGC CTCCACTCTC901TCATCAGACC TTTCTTAACA AAGGGCTTAG TAAATCTATG GGATTTCTGT CCATCAAAGA961TACACAAGAT GAGAATTATT TCAAGGACAT TTTATCAGAT AATTCTGGAC GTGAAGATTC1021TGAAAATACA TTCTCCCCTT ACCAGTTCAA AACTAGTGGC CCAGAAAAAA AACCCATCCC1081TGGCATTGAT GTGCTTTCTA AGAAGAAGAT CTGGGCTTCA TCCATGGACT TGCTTTGTAC1141AGCTGACAGA GACTTCTCTT CAGGAGAGAC TGCCACATAT CGTCGTTGTC ACCCTGAGGC1201AGTAACAGTG CGGACTTCAA CTACTCCTAG AAAAAAGGAG GCAAGATACT CAGATGGAAG1261TATAGCCTTG GATATCTTTG GCCCTCAGAA AATGGATCCA ATATATCACA CTCGAGAATT1321GCCCACCTCC TCAGCAATAT CAAGTGCTTT CGACCGAATC CGAGAGAGAC AAAAGAAACT1381TCAGGTTCTG AGGGAAGCCA TGAATGTAGA AGAACCAGTT CGAAGATACA AAACTTATCA1441TGGTGATGTC TTTAGTACCT CCAGTGAAAG TCCATCTATT ATTTCCTCTG AATCAGATTT1501CAGACAAGTG AGAAGAAGTG AAGCCTCAAA GAGGTTTGAA TCCAGCAGTG GTCTCCCAGG1561GGTAGATGAA ACCTTAAGTC AAGGCCAGTC ACAGAGACGG AGCAGACAAT ATGAAACACC1621CTTTGAAGGC AACTTAATTA ATCAAGAGAT CATGCTAAAA CGGCAAGAGG AAGAACTGAT1681GCAGCTACAA GCCAAAATGG CCCTTAGACA GTCTCGGTTG AGCCTATATC CAGGAGACAC1741AATCAAAGCG TCCATGCTTG ACATCACCAG GGATCCGTTA AGAGAAATTG CCCTAGAAAC1801AGCCATGACT CAAAGAAAAC TGAGGAATTT CTTTGGCCCT GAGTTTGTGA AAATGACAAT1861TGAACCATTT ATATCTTTGG ATTTGCCACG GTCTATTCTT ACTAAGAAAG GGAAGAATGA1921GGATAACCGA AGGAAAGTAA ACATAATGCT TCTGAACGGG CAAAGACTGG AACTGACCTG1981TGATACCAAA ACTATATGTA AAGATGTGTT TGATATGGTT GTGGCACATA TTGGCTTAGT2041AGAGCATCAT TTGTTTGCTT TAGCTACCCT CAAAGATAAT GAATATTTCT TTGTTGATCC2101TGACTTAAAA TTAACCAAAG TGGCCCCAGA GGGATGGAAA GAAGAACCAA AGAAAAAGAC2161CAAAGCCACT GTTAATTTTA CTTTGTTTTT CAGAATTAAA TTTTTTATGG ATGATGTTAG2221TCTAATACAA CATACTCTGA CGTGTCATCA GTATTACCTT CAGCTTCGAA AAGATATTTT2281GGAGGAAAGG ATGCACTGTG ATGATGAGAC TTCCTTATTG CTGGCATCCT TGGCTCTCCA2341GGCTGAGTAT GGAGATTATC AACCAGAGGT TCATGGTGTG TCTTACTTTA GAATGGAGCA2401CTATTTGCCC GCCAGAGTGA TGGAGAAACT TGATTTATCC TATATCAAAG AAGAGTTACC2461CAAATTGCAT AATACCTATG TGGGAGCTTC TGAAAAAGAG ACAGAGTTAG AATTTTTAAA2521GGTCTGCCAA AGACTGACAG AATATGGAGT TCATTTTCAC CGAGTGCACC CTGAGAAGAA2581GTCACAAACA GGAATATTGC TTGGAGTCTG TTCTAAAGGT GTCCTTGTGT TTGAAGTTCA2641CAATGGAGTG CGCACATTGG TCCTTCGCTT TCCATGGAGG GAAACCAAGA AAATATCTTT2701TTCTAAAAAG AAAATCACAT TGCAAAATAC ATCAGATGGA ATAAAACATG GCTTCCAGAC2761AGACAACAGT AAGATATGCC AGTACCTGCT GCACCTCTGC TCTTACCAGC ATAAGTTCCA2821GCTACAGATG AGAGCAAGAC AGAGCAACCA AGATGCCCAA GATATTGAGA GAGCTTCGTT2881TAGGAGCCTG AATCTCCAAG CAGAGTCTGT TAGAGGATTT AATATGGGAC GAGCAATCAG2941CACTGGCAGT CTGGCCAGCA GCACCCTCAA CAAACTTGCT GTTCGACCTT TATCAGTTCA3001AGCTGAGATT CTGAAGAGGC TATCCTGCTC AGAGCTGTCG CTTTACCAGC CATTGCAAAA3061CAGTTCAAAA GAGAAGAATG ACAAAGCTTC ATGGGAGGAA AAGCCTAGAG AGATGAGTAA3121ATCATACCAT GATCTCAGTC AGGCCTCTCT CTATCCACAT CGGAAAAATG TCATTGTTAA3181CATGGAACCC CCACCACAAA CCGTTGCAGA GTTGGTGGGA AAACCTTCTC ACCAGATGTC3241AAGATCTGAT GCAGAATCTT TGGCAGGAGT GACAAAACTT AATAATTCAA AGTCTGTTGC3301GAGTTTAAAT AGAAGTCCTG AAAGGAGGAA ACATGAATCA GACTCCTCAT CCATTGAAGA3361CCCTGGGCAA GCATATGTTC TAGGAATGAC TATGCATAGT TCTGGAAACT CTTCATCCCA3421AGTACCCTTA AAAGAAAATG ATGTGCTACA CAAAAGATGG AGCATAGTAT CTTCACCAGA3481AAGGGAGATC ACCTTAGTGA ACCTGAAAAA AGATGCAAAG TATGGCTTGG GATTTCAAAT3541TATTGGTGGG GAGAAGATGG GAAGACTGGA CCTAGGCATA TTTATCAGTT CAGTTGCCCC3601TGGAGGACCA GCTGACTTGG ATGGATGCTT GAAGCCAGGA GACCGTTTGA TATCTGTGAA3661TAGTGTGAGT CTGGAGGGAG TCAGCCACCA TGCTGCAATT GAAATTTTGC AAAATGCACC3721TGAAGATGTG ACACTTGTTA TCTCTCAGCC AAAAGAAAAG ATATCCAAAG TGCCTTCTAC3781TCCTGTGCAT CTCACCAATG AGATGAAAAA CTACATGAAG AAATCTTCCT ACATGCAAGA3841CAGTGCTATA GATTCTTCTT CCAAGGATCA CCACTGGTCA CGTGGTACCC TGAGGCACAT3901CTCGGAGAAC TCCTTTGGGC CGTCTGGGGG CCTGCGGGAA GGAAGCCTGA GTTCTCAAGA3961TTCCAGGACT GAGAGTGCCA GCTTGTCTCA AAGCCAGGTC AATGGTTTCT TTGCCAGCCA4021TTTAGGTGAC CAAACCTGGC AGGAATCACA GCATGGCAGC CCTTCCCCAT CTGTAATATC4081CAAAGCCACC GAGAAAGAGA CTTTCACTGA TAGTAACCAA AGCAAAACTA AAAAGCCAGG4141CATTTCTGAT GTAACTGATT ACTCAGACCG TGGAGATTCA GACATGGATG AAGCCACTTA4201CTCCAGCAGT CAGGATCATC AAACACCAAA ACAGGAATCT TCCTCTTCAG TGAATACATC4261CAACAAGATG AATTTTAAAA CTTTTTCTTC ATCACCTCCT AAGCCTGGAG ATATCTTTGA4321GGTTGAACTG GCTAAAAATG ATAACAGCTT GGGGATAAGT GTCACGGTAC TGTTTGACAA4281GGGAGGTGTG AATACGAGTG TCAGACATGG TGGCATTTAT GTGAAAGCTG TTATTCCCCA4441GGGAGCAGCA GAGTCTGATG GTAGAATTCA CAAAGGTGAT CCCGTCCTAC CTGTCAATGG4501AGTTAGTCTA GAAGGAGCCA CCCATAAGCA AGCTCTGGAA ACACTCACAA ATACAGGACA4561GGTGCTTCAT CTGTTATTAG AAAAGGGACA ATCTCCAACA TCTAAAGAAC ATGTCCCGGT4621AACCCCACAG TGTACCCTTT CAGATCAGAA TGCCCAAGGT CAAGGCCCAG AAAAACTGAA4681GAAAACAACT CAGGTCAAAG ACTACAGCTT TGTCACTGAA GAAAATACAT TTGAGGTAAA4741ATTATTTAAA AATAGCTCAG GTCTAGGATT CAGTTTTTCT CGAGAAGATA ATCTTATACC4801GGAGCAAATT AATGCCAGCA TAGTAAGGGT TAAAAAGCTC TTTCCTGGAC AGCCAGCAGC4861AGAAAGTGGA AAAATTGATC TAGGAGATGT TATCTTGAAA GTGAATGGAG CCTCTTTGAA4921AGGACTATGT CAGCAGGAAG TCATATCTGC TCTCAGGGGA ACTGCTGCAG AAGTATTCTT4981GCTTCTCTGC AGACCTCCAC CTGGTGTGCT ACCGGAAATT GATACTGCGC TTTTGACCCC5041ACTTCAGTCT CCAGCACAAG TACTTCCAAA CAGCAGTAAA GACTCTTCTC AGCCATCATG5101TGTGGAGCAA AGCACCAGCT CAGATGAAAA TGAAATGTCA GACAAAAGCA AAAAACAGTG5161CAAGTCCCCA TCCAGAAGAG ACAGTTACAG TGACAGCAGT GGGAGTGGAG AAGATGACTT5221AGTGACAGCT CCAGCAAACA TATCAAATTC GACCTGGAGT TCAGCTTTGC ATCAGACTCT5281AAGCAACATG GTATCACAGG CACAGAGTCA TCATGAAGCA CCCAAGAGTC AAGAAGATAC5241CATTTGTACC ATGTTTTACT ATCCTCAGAA AATTCCCAAT AAACCAGAGT TTGAGGACAG5401TAATCCTTCC CCTCTACCAC CGGATATGGC TCCTGGGCAG AGTTATCAAC CCCAATCAGA5461ATCTGCTTCC TCTAGTTCGA TGGATAAGTA TCATATACAT CACATTTCTG AACCAACTAG5521ACAAGAAAAC TGGACACCTT TGAAAAATGA CTTGGAAAAT CACCTTGAAG ACTTTGAACT5581GGAAGTACAA CTCCTCATTA CCCTAATTAA ATCAGAAAAA GGAAGCCTGG GTTTTACAGT5641AACCAAAGCC AATCAGAGAA TTGGTTGTTA TGTTCATGAT GTCATACAGG ATCCAGCCAA5701AAGTGATGGA AGGCTAAAAC CTCGGGACCG GCTCATAAAG GTTAATGATA CAGATGTTAC5761TAATATGACT CATACAGATG CAGTTAATCT GCTCCGGGCT GCATCCAAAA CAGTCAGATT5821AGTTATTCGA CGAGTTCTAG AATTACCCAG AATACCAATG TTGCCTCATT TGCTACCGGA5881CATAACACTA ACGTGCAACA AAGAGGAGTT GGGTTTTTCC TTATGTGGAG GTCATGACAG5941CCTTTATCAA GTGGTATATA TTAGTGATAT TAATCCAAGG TCCGTCGCAG CCATTGAGGG6001TAATCTCCAG CTATTAGATG TCATCCATTA TGTGAACGGA GTCAGCACAC AAGGAATGAC6061CTTGGAGGAA GTTAACAGAG CATTAGACAT CTCACTTCCT TCATTGGTAT TGAAACCAAC6121AAGAAATGAT CTTCCAGTGG TCCCCAGCTC AAAGAGGTCT GCTGTTTCAG CTCCAAAGTC6181AACCAAAGGC AATGGTTCCT ACAGTGTGGG GTCTTCCAGC CAGCCTGCCC TCACTCCTAA6241TGATTCATTC TCCACGGTTG CTGGGGAAGA AATAAATGAA ATATCGTACC CCAAAGGAAA6301ATGTTCTACT TATCAGATAA AGGGATCACC AAACTTGACT CTGCCCAAAG AATCTTATAT6261ACAAGAAGAT GACATTTATG ATGATTCCCA AGAAGCTGAA GTTATCCAGT CTCTGCTGGA6421TGTTGTGGAT GAGGAAGCCC AGAATCTTTT AAACGAAAAT AATGCAGCAG GATACTCCTG6481TGGTCCAGGT ACATTAAAGA TGAATGGGAA GTTATCAGAA GAGAGAACAG AAGATACAGA6541CTGCGATGGT TCACCTTTAC CTGAGTATTT TACTGAGGCC ACCAAAATGA ATGGCTGTGA6601AGAATATTGT GAAGAAAAAG TAAAAAGTGA AAGCTTAATT CAGAAGCCAC AAGAAAAGAA6661GACTGATGAT GATGAAATAA CATGGGGAAA TGATGAGTTG CCAATAGAGA GAACAAACCA6721TGAAGATTCT GATAAAGATC ATTCCTTTCT GACAAACGAT GAGCTCGCTG TACTCCCTGT6781CGTCAAAGTG CTTCCCTCTG GTAAATACAC GGGTGCCAAC TTAAAATCAG TCATTCGAGT6841CCTGCGGGGT TTGCTAGATC AAGGAATTCC TTCTAAGGAG CTGGAGAATC TTCAAGAATT6801AAAACCTTTG GATCAGTGTC TAATTGGGCA AACTAAGGAA AACAGAAGGA AGAACAGATA6961TAAAAATATA CTTCCCTATG ATGCTACAAG AGTGCCTCTT GGAGATGAAG GTGGCTATAT7021CAATGCCAGC TTCATTAAGA TACCAGTTGG GAAAGAAGAG TTCGTTTACA TTGCCTGCCA7081AGGACCACTG CCTACAACTG TTGGAGACTT CTGGCAGATG ATTTGGGAGC AAAAATCCAC7141AGTGATAGCC ATGATGACTC AAGAAGTAGA AGGAGAAAAA ATCAAATGCC AGCGCTATTG7201GCCCAACATC CTAGGCAAAA CAACAATGGT CAGCAACAGA CTTCGACTGG CTCTTGTGAG7261AATGCAGCAG CTGAAGGGCT TTGTGGTGAG GGCAATGACC CTTGAAGATA TTCAGACCAG7221AGAGGTGCGC CATATTTCTC ATCTGAATTT CACTGCCTGG CCAGACCATG ATACACCTTC7381TCAACCAGAT GATCTGCTTA CTTTTATCTC CTACATGAGA CACATGCACA GATCAGGCCC7441AATCATTACG CACTGCAGTG CTGGCATTGG ACGTTCAGGG ACCCTGATTT GCATAGATGT7501GGTTCTGGGA TTAATCAGTC AGGATCTTGA TTTTGACATC TCTGATTTGG TGCGCTGCAT7561GAGACTACAA AGACACGGAA TGGTTCAGAC AGAGGATCAA TATATTTTCT GCTATCAAGT7621CATCCTTTAT GTCCTGACAC GTCTTCAAGC AGAAGAAGAG CAAAAACAGC AGCCTGAGGT7681TCTGAAGTGA CATGAAAAGA GCCTCTGGAT GCATTTCCAT TTCTCTCCTT AACCTCCAGC7741AGACTCCTGC TCTCTATCCA AAATAAGATC ACAGAGCAGC AAGTTCATAC AACATGCATG7801TTCTCCTCTA TCTTAGAGGG GTATTCTTCT TGAAAATAAA AAATATTGAA ATGCTGTATT7861TTTACAGCTA CTTTAACCTA TGATAATTAT TTACAAAATT TTAACACTAA CCAAACAATG7821CAGATCTTAG GGATGATTAA AGGCAGCATT TGATGATAGC AGACATTGTT ACAAGGACAT7981GGTGAGTCTA TTTTTAATGC ACCAATCTTG TTTATAGCAA AAATGTTTTC CAATATTTTA8041ATAAAGTAGT TATTTTATAG GGGATACTTG AAACCAGTAT TTAAGCTTTA AATGACAGTA8101ATATTGGCAT AGAAAAAAGT AGCAAATGTT TACTGTATCA ATTTCTAATG TTTACTATAT8161AGAATTTCCT GTAATATATT TATATACTTT TTCATGAAAA TGGAGTTATC AGTTATCTGT8221TTGTTACTGC ATCATCTGTT TGTAATCATT ATCTCACTTT GTAAATAAAA ACACACGTTA8281AAACATGGENEANK ID: NM_003326.1VERSION NM_003336.1 GI:4507768MSTPARRRLNRDFKRLQEDFPAGVSGAPSENNINVWNAVIFGPEGTPFGDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDCGENBANK ID: S40706.1VERSION S40706.1 GI:252001MAAESLPFSSDTVSWELEAWYEDLQEVLSSDENCGTYVSPPGNESEESKIETTLDPASLAWLTEEEPEPAEVTSTSQSPHSPDSSQSSLAQEEEEEDQGRTRKRKQSGHSPARAGKQRNKEKEQENERKVAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQAGENBANK ID: M96995.1VERSION M96995.1 GI:181975MEAIAKYDEKATADDELSFKRGDILKVLNEECDQNNYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEENLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQWFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACNGQTGMFPRNYVTPVNRNVGENBANK ID: M21758.1VERSION M21758.1 GI:183664MAEKPKLHYFNARGRNESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLNEQQVPNVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGENILLLPVCPPEEKDAKLALIKEKIKNRYFPAEEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSEPLLKALKTRISNLPTVKKFLQPGSPRKPPNDEKSLEEARKIFRFGENBANK ID: U32944.1VERSION U32944.1 GI:1209060MCDRKAVIKNADMSEENQQDSVECATQALEKYNIEKDIAARIKKEFDKKYNPTWHCIVGRNFGSYVPMETKHFIYFYLGQVAILLFKSGGENBANK ID: NM_021141.2VERSION NM_021141.2 GI:12406650MVRSGNKAAVVLCNDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFGTDGTDNPLSGGDQYQNITVHRRLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGDGPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFRYQSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLINALDDLDMVAIVRYAYDKRANPQVGVAFPHIKMNYECLVYVQLPFNEDLRQYNFSSLKNSKKYAPTEAQLNAVDALIDSNSLAKKDEKTDTLEDLFPTTKIPNPRFQRLRQCLLMRALHPREPLPPIQQHIWNNLNPPAEVTTKSQIPLSKIKTLEPLIEAKKKDQVTAQEIFQDNMEDGPTAKKLKTEQGGAMESVSSLAEQSVTSVGSVNPAENFRVLVKQKKASEEEASNQLINHIEQFLDTNETPYFNKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFNEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFEEGGDVDDLLDMIGENBANK ID: NM_005053.1VERSION NM_005053.1 GI:4826963MAVTITLKTLQQQTFKIRNEPDETVKVLKEKIEAEKGRDAFPVADQKLIYAGKILSDDVPIRDYRIDEKNFVVVNVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETNLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEMGSVQESQVSEQPATEAAGENPLEFLRDQPQEQNNRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQNNYIQVTPQEKEAIERLKALGEPESLVIQAYFACEKNENLAANFLLSQNFDDEGENBANK ID: Z23115.1VERSION Z23115.1 GI:510900MSQSNEELVVDFLSYKLSQEKGYSWSQFSDVEENETEAPEGTESEMETPSAINGNPSWNLADSPAVNGATAHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFWSEGGALCVESVDKEMQVLVSRIAAWMATYLNDHLETWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGNTVAGVVLLGSLFSRKGENBANK ID: AB020979.1VERSION AB02D979.1 GI:6518501MDEADRRLLRRCRLRLVEELQVDQLWDALLSSELFRPHNIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLETNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVEQKDHGFEVASTSTEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQNPGCFNFLRKKLFFKTSGENBANK ID: U21092.1VERSION U21092.1 GI:726087MESSKKNDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRTCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLTLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSNCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNMEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDLPDPGENBANK ID: NM_001459.1VERSION NM_001459.1 GI:4503750MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGALWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPNSPRPLEATAPTAPQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPYPSPQDLLLVEHGENBANK ID: X57500.1VERSION M36089.1 GI:340396MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAG0AGEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPYTASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPRGEGTEPRRPRAGPEELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSRRYLMAGPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKEHRLPPGQEENGEDPYA0STDENTDSEEHQEPPDLPVPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQAGENBANK ID: BAA02962.1DEFINITION HUMAN MRNA FOR RECA-LIKE PROTEIN HSRAD51, COMPLETE CDS.VERSION 013804.1 GI:397826CDS 212..1231/CODON_START=11GAATTCCGGT AAGGAGAGTG CGGCCCTTCC CGAGGCGTGC AGCTGGGAAC TGCAACTCAT61CTGGGTTGTG CGCAGAAGGC TGGGGCAAGC GAGTAGAGAA GTGCACCGTA AGCCAGCGGG121CTTGGGCGCC GTCCGGCCGG GTCGCGTGCA GCCCCGCGGG GTGAAGTCGG AGCGCGGGGC181CTGCTGGAGA GAGGAGCGCT GCGACCGAGT AATGGCAATG CAGATGCAGC TTGAAGCGAA241TGCAGATACT TCAGTCGAAG AAGAAAGCTT TGGCCCACAA CCCATTTGAC GGTTAGAGCA301GTGTGGCATA AATGCCAACG ATGTGAAGAA ATTCGAAGAA GCTGGATTCC ATACTGTGGA361GGCTGTTGCC TATGCGCCAA ACAAGCAGCT AATAAATATT AAGGGAATTA GTGAAGCCAA421AGCTGATAAA ATTCTGGCTG AGGCAGCTAA ATTAGTTCCA ATGGGTTTCA CCACTGCAAC481TGAAPTCCAC CAAACGCGGT CAGAGATCAT ACAGATTACT ACTGGCTCCA AAGAGCTTGA541CAAACTACTT CAAGGTGGAA TTGAGACTGG ATCTATCACA GAAATGTTTG GAGAATTCCG601AACTGGGAAG ACCCAGATCT GTCATACGCT AGCTGTCACC TGCCAGCTTC CCATTGACCG661GGGTGGAGGT GAAGGAAACG CCATGTACAT TGACACTGAG GGTACCPTTA GGCCAGAACG721GCTGCTGGCA GTGGCTGAGA GGTATGCTCT CTCTGGCAGT GATGTCCTGG ATAATGTAGC781ATATGCTCGA GCGTTCAACA CAGACCACCA GACCCAGCTC CTTTATCAAG CATCAGCCAT841GATGGTAGAA TCTAGGTATG CACTGCTTAT TGTAGACAGT GCCACCGCCC TTTACAGAAC901AGACTACTGG GGTCGAGGTG AGCTTTCAGC CAGGCAGATG CACTTGGCCA GGTTTCTGCG961GATCCTTCTG CGACTCGCTG ATGAGTTTGG TGTAGCAGTG GTAATCACTA ATCAGGTGGT1021AGCTCAAGTG GATGGAGCAG CGATGTTTGC TGCTGATCCC AAAAAACCTA TTGGAGGAAA1081TATCATCGCC CATGCATCAA CAACCAGATT GTATCTGAGG AAAGGAAGAG GGGAAACCAG1141AATCTGCCAA ATCIACGACT CTCCCTGTCT TCCTGAAGCT GAAGCTATGT TCGCCATTAA1201ICCAGAIGGA GTGGGAGATG CCAAAGACTG AATCATTGGG TTTTTCCTCT GTTAAAAACC1261TTAAGTGCTG CAGCCTAATG AGAGTGCACT GCTCCCTGGG GTTCTCTACA GGCCTCTTCC1321TGTTGTGACT GCCAGGATAA AGCTTCCGGG AAAACAGCTA TTATATCAGC TTTTCTGATG1381GTATAAACAG GAGACAGGTC AGTAGTCACA AACTGATCTA AAATGGTTTA TTCCTTCTGT1441AGTGTATTAA TCTCTGTGTG TTIICTTTGG TTTTGGAGGA GGGTATGAAG TATCTTTGAC1501ATGGTGCCTT AGGAATGACT TGGGTTTAAC AAGCTGTCTA CTGGACAATC TTATGTTTCC1561AAGAGAACTA AAGCTGGAGA GACCTGACCC TTCTCTCACT TCTAAATTAA TGGTAAAATA1621AAAGTCCTCA GCTATGTAGC AAAGGGENBANK ID: B56529AGGAGGTGCAGGAGAACAGAAGTGTGCCCTGTGCTCTTCTGAGCAGAGAAGCACCATGAGCTGGGGCAGGCAAACCCCACTGGGGCTGGCATGGCTCGCTGGGGCTGGCACGTGGAGGGAAGTGCTGCCTCCCCAGGCCTCTGCTTTAATGATCAGCTTAGTCACTGGTGTGACTGTGCCCTGGGCTATTGCCTGAGGTGAAACCTTTACCTGCTCCCTGGTCTATCTTGGTAGAATTGATCTATTTCAAAGGTATACAGCTAAGCAGATTCTTATTTCTGAGAATACCACCTGTGTGGCACCTCCTTTCCAGCTCCTCAGGGAATGTGAGACATGTGAGGAGCTGCCACACTCCTTGCCAGTAGTCACAGGAAAGGGTGGTTAACAAGTTAAAGTAACCAAGAGGAATATGTGTGTTGAGTCAGCTGATGGCGTTTGCAAGTGGAATGTCCTTCTTACCGENBANK ID: CAA59230.1DEFINITION H. SAPIENS MRNA FOR DNA LIGASE III.VERSION X84740.1 GI:860962CDS 334..3102/CODON_START=11CCACGCGTCC GGCAGCCTGT ATGAGCAAGT GCCGAGGCCT ACGGTGAGCG CCGGAGCCGG61AGAGGCAGCT ATATGTCTTT GGCTTTCAAG ATCTTCTTTC CACAAACCCT CCGTGCACTC121AGCCGAAAAG AACTGTGCCT ATTCCGAAAA CATCACTGGC GTGATGTAAG ACAATTCAGC181CAGTGGTCAG AAACAGATCT GCTTCATGGA CATCCCCTCT TCCTGAGAAG AAAGCCTGTT241CTATCATTCC AGGGAAGCCA TCTAAGATCA CGTGCCACCT ACCTTGTTTT CTTGCCAGGG301TTGCATGTGG GACTCTGCAG TGGCCCCTGT GAGATGGCTG AGCAACGGTT CTGTGTGGAC361TATGCCAAGC GTGGCACAGC TGGCTGCAAA AAATGCAAGG AAAAGATTGT GAAGGGCGTA421TGCCGAATTG GCAAAGTGGT GCCCAATCCC TTCTCAGAGT CTGGGGGTGA TATGAAAGAG481TGGTACCACA TTAAATGCAT GTTTGAGAAA CTAGAGCGGG CCCGGGCCAC CACAAAAAAA541ATCGAGGACC TCACAGAGCT GGAAGGCTGG GAAGAGCTGG AAGATAATGA GAAGGAACAG601ATAACCCAGC ACATTGCAGA TCTGTCTTCT AAGGCAGCAG GTACACCAAA GAAGAAAGCT661GTTGTCCAGG CTAAGTTGAC AACCACTGGC CAGGTGACTT CTCCAGTGAA AGGCGCCTCA721TTTGTCACCA GTACCAATCC CCGGAAATTT TCTGGCTTTT CAGCCAAGCC CAACAACTCT781GGGGAAGCCC CCTCGAGCCC CACCCCTAAG AGAAGTCTGT GTTCAAGCAA ATGTGACCCC841AGGCATAAGG ACTGTCTGCT ACGGGAGTTT CGAAAGTTAT GCGCCATGGT GGCCGATAAT901CCTAGCTACA ACACGAAGAC CCAGATCATC CAGGACTTCC TTCGGAAAGG CTCAGCAGGA961GATGGTTTCC ACGGTGATGT GTACCTAACA GTGAAGCTGC TGCTGCCAGG AGTCATTAAG1021ACTGTTTACA ACTTGAACGA TAAGCAGATT GTGAAGCTTT TCAGTCGCAT TTTTAACTGC1081AACCCAGATG ATATGGCACG GGACCTAGAG CAGGGTGACG TGTCAGAGAC AATCAGAGTC1141TTCTTTGAGC AGAGCAAGTC TTTCCCCCCA GCTGCCAAGA GCCTCCTTAC CATCCAGGAA1201GTGGATGAGT TCCTTCTGCG GCTGTCCAAG CTCACCAAGG AGGATGACCA GCAACAGGCC1261CTACAGGACA TTGCCTCCAG GTGTACAGCC AATGACCTTA AATGCATCAT CAGGTTGATC1321AAACATCATC TGAAGATGAA CTCAGGTGCA AAACATGTGT TAGACGCCGT TGACCCCAAT1381GCCTATGAAG CCTTCAAAGC CTCGCCCAAC CTGCAGGATG TGGTGGAGCG GGTCCTTCAC1441AACGCGCAGG AGGTGGAGAA GGAGCCGGGC CAGAGACCAG CTCTGAGCGT CCAGGCCTCG1501CTGATGACAC CTGTGCAGCC CATGTTGGCG GAGGCCTGCA AGTCCGTTGA GTATGCAATG1561AAGAAATGTC CCAATGGCAT GTTCTCTGAG ATCAAGTACG ATGGAGAGCG AGTCCAGGTG1621CATAAGAATG GAGACCACTT CAGCTACTTC AGCCGCAGTC TCAAGCCCGT CCTTCCTCAC1681AAGGTGGCCC ACTTTAAGGA CTACATTCCC CAGGCTTPTC CTGGGGGCCA CAGCATGATC1741TTGGATTCTG AAGTGCTTCT GATTGACAAC AAGACAGGCA AACCACTGCC CTTTGGGACT1801CTGGGAGTAC ACAAGAAAGC AGCCTTCCAG GATGCTAATG TCTGCCTGTT TGTTTTTGAT1861TGTATCTACT TTAATGATGT CAGCTTGATG GACAGACCTC TGTGTGAGCG GCGGAAGTTT1921CTTCATGACA ACATGGTTGA AATTCCAAAC CGGATCATGT TCTCAGAAAT GAAGCGAGTC1981ACAAAAGCTT TGGACTTGGC TGACATGATA ACCCGGGTGA TCCAGGAGGG ATTGGAGGGG2041CTGGTGCTGA AGGATGTGAA GGGTACATAT GAGGCTGGGA AGCGGCACTG GCTGAAAGTG2101AAGAAAGACT ATTTGAACGA GGGGGCCATG GCCGACACAG CTGACCTGGT GGTCCTTGGA2161GCCTTCTATG GGCAAGGGAG CAAAGGCGGC ATGATGTCAA TCTTCCTCAT GGGCTGCTAC2221GACCCTGGCA GCCAGAAGTG GTGCACAGTC ACCAAGTGTG CAGGAGGCCA TGATGATGCC2281ACGCTTGCCC GCCTGCAGAA TGAACTAGAC ATGGTGAAGA TCAGCAAGGA CCCCAGCAAA2341ATACCCAGCT GGTTGAAGGT CAACAAGATC TACTATGCTG ACTTCATCGT CCCAGACCCA2401AAGAAAGCTG CCGTGTGGGA GATCACAGGG GCTGAATTCT CCAAATCGGA GGCTCATACA2461GCTGACGGGA TCTCCATCCG ATTCCCTCGC TGCACCCGAA TCCGAGATGA TAAGGACTGG2521AAATCTGCCA CTAACCTTCC CCAACTCAAG GAACTGTACC AGTTGTCCAA GGAGAAGGCA2581GACTTCACTG TAGTGGCTGG AGATGAGGGG AGCTCCACTA CAGGGGGTAG CAGTGAAGAG2641AATAAGGGTC CCTCAGGGTC TGCTGTGTCC CGCAAGGCCC CCAGCAAGCC CTCAGCCAGT2701ACCAAGAAAG CAGAAGGGAA GCTGAGTAAC TCCAACAGCA AAGATGGCAA CATGCAGACT2761GCAAAGCCTT CCGCTATGAA GGTGGGGGAG AAGCTGGCCA CAAAGTCTTC TCCAGTGAAA2821GTAGGGGAGA AGCGGAAAGC TGCTGATGAG ACGCTGTGCC AAACAAAGGT ATTGCTGGAC2881ATCTTCACTG GGGTGCGGCT TTACTTGCCA CCCTCCACAC CAGACTTCAG CCGTCTCAGA2941CGCTACTTTG TGGCATTCGA CGGGGACCTG GTACAGGAAT TTGATATGAC TTCAGCCACG3001CACGTGCTGG GTAGCAGGGA CAAGAACCCT GCGGCCCAGC AGGTCTCCCC AGAGTGGATT3061TGGGCATGTA TCCGGAAACG GAGACTGGTA GCTCCCTGCT AGGTTTGCTG TCTTCCCTCT3121CCCTCAGGCC ATACTCTCCT TTACCATACT ATTGGACTGG ACTCAGGCTG GAGGCAGATA3181GACACAGTAT AGGGGGAATG GGCTTGCTTC TCCCAAACCC ACCAGTTCTC CACTGTCTCT3241TCTGGACCAG GAATTAGTTG CTGTGGGTGC CACAGCTGAA GTCAGTTTGT CTTGCTGGTT3301TAAATAGATC TTTCAGAGCT GGGTGCTGGG TTTGCCATCT TTTTGTTTTC TTTGAAAAGC3361AGCTTAGTTA CCCTTTTTAT AAATAAAATA TCTTGCAGTT AAAAAAAAAA AAAAAAAAAA3421AAGENBANK ID: D26155.1VERSION D26155.1 GI:505086MSTPTDPGAMPHPGPSPGPGPSPGPILGFSPGPGPSPGSVESMMGESPGPPSVSHPMPTNGSTDFPQEGMHQMHKPIDGIHDKGIVEDTHCGSNKGTGMRPPHPGNGPPQSPMDQHSQGMSPHPSPLGAPEHVSSPMSGGGPTPPQYSPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRAQILAYKMLARGQFLPETLQLAVQGKRTLPGLQQQQQQQQGQQQQQQQQQQQQQPQQQPQQQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPFAAAVPGPSVPQFAPGQPSFVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELENLFGSLPPDLRTKATVELKALRLLNFQRQLREEVVACNRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYNRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEESYRKLIDQKKDRRLAYLLQQTGEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDSSSQNSDLPVKVTNTETGKVLFGPEAPKASQLDANLEMNPGYEVAPRSDSSESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVFLSTLSNNTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGNRMKNHHCKLTQVLNTEYVAPRRILLTGTPLQNKLPELWALLNELLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLEKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYNFQHIESSFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLNTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAAHTVVIFDSDWNPHQDLQAQDRARRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNV0QKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNFKRKPRLNESDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVDKDFAKEDVEKAKHRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHRYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKKIKLNKKDDKCRDKGKGKKRPNRGKAKFVVSDFDSDEEQDEREQSEGSGTDDEGENBANK ID: M62829JVERSION M62829.1 GI:182262MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGAFBGSGSNSSSSSSGGGGGGGGGSNSSSSSSTENPQADTGEQPYEHLTAESFFDISLNNEKVLVETSYFSQTTRLPFITYTGRFSLEPAPNSGNTLWPEFLFSLVSGLVSNTNPPASSSSAPSFAASSASASQSPPLSCAVBSNDSSPIYSAAFTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAYPAAKGGFQVFNIPDYLFPQQQGDLGLCTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSGSQDLKALNTSYQSQLIKPSRMRKYFNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRETKIHLRQKDKKADKSVVASRATSSLSSYFSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSSTYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVTNSFSASTGLSDNTATFSFRTIEICGENBANK ID: U10421.1VERSION U10421.1 GI:500756MDNARMNSFLEYPILSSGGSGTCSARAYFSDBRITTFQSCAVSANSCGGDDRFLVGRGVQIGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHESCQPSYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWNKVKRNFPKTGKVGEYGYLGQFNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSHGENBANK ID: U08015.1VERSION U08015.1 GI:500631MPSTSFPVPSKFPLGPAAAVFGRGETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHSTLPAPCHNLQTSTPGIIPPADHPSGYGAALDGGPAGYFLSSGHTRPDGAFALESPRIEITSCLGLYHNNNQFFHDVEVEDVLPSSKRSPSTATLSLFSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSPWQSPCVSPKTTDPEEGFPRGLGACTLLGSPQHSFSTSPRASVTEESWLGARSSRPASPCNKRKYSLNGRQPPYSPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQEIRKGGFCDQYLAVPQNPYQWAKPKPLSPTSYNSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDICRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWENEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANGNAIFLTVSREHERVGCFFGENBANK ID: U08191.1VERSION U08191.1 GI:476273MTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIRIIKSEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLESQASLFNLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLNLETKDQAFCKQENEGSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRFAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAFDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLER0RSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSNPFTPVTPVTPTTPALPAIPISPPPVSAVNKSGFSTVSEPAKSSSGVLLVSSFTNPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVFATATQTKVVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTGQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLFPSSITTDAKGQTVLRITPDNMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNFVNAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLNPALGVSVADQKGKSTVASSEARPAATIRIVQGLGVNPPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSNNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQACKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASISNREQLLAPPKQSPLLLGENBANK ID: M55654VERSION M55654.1 GI:339491MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQILTTAPLPGTTPLYPSPMTPNTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVINRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGEPAKELDFKIQNNVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSQKVVLTGAKVRAEIYEAFENIYPILKGFRKTTGENBANK ID: NM_005568.1VERSION NM_005568.1 GI:5031866MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCRQGISPSDLVRRARSKVFHLNCFTCNNCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLRSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNEN0DQNLGAERRGPGTTIKAKQLETLKAAFAATPKPTREIREQLAQETGLNMRVIQVNFQNRRSKERRMKQLSALAGHAFERSPRRMRPLVDRLEPGELIPNGFFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSNSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVWGENBANK ID: X69111.1VERSION X69111.1 GI:32294MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELAPELVISNDKRSFCHGENBANK ID: NP_000507.1VERSION NP_000507.1 GI:45040471MGCLGNSETE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM61RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA121NPENQFRVDY ILSVMNVPDF DWPPEFYEHA KALWEDEGVR ACYERSNEYQ LIDCAQYFLD181KIDVIEQADY VPSDQDLLRC RVLTSGIFET KFQVDKVNFH NFDVGGQRDE RRKWIQCFND241VTAIIFVVAS SSYNMVIRED NQTNRLQEAL NLFKSIWNNR WLRTISVILF LNKQDLLAEK301VLAGKSKIED YFPEFARYTT PEDATPEPGE DPRVTRAKYF IRDEFLEIST ASGDGRHYCY361PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ YELLGENBANK ID: AAA40889.1VERSION AAA40889.1 GI:2033571MEQYTANSNS STEQIVVQAG QIQQQQQGGV TAVQLQTEAQ VASASGQGVG TLQVVQGQPL61NVQVSGGQLI TSTGQPINVQ AVPGGQGQTI MQVPVSGTQG LQQIQLVPPG QIQIQGGQAV121QVQGQQGQTQ QIIIQQPQTA VTAGQTQTQQ QIAVQGQQVA QTAEGQTIVY QPVNADGTIL181QQGMITIPAA SLAGAQIVQT GANTNTTSSG QGTVTVTLPV AGNVVNSGGM VMMVPGAGSV241PAIQRIPLPG AEMLEEEPLY VNAKQYHRIL KRRQARAKLE AEGKIPKERR KYLHESRHRH301AMARKRGEGG RFFSPKEKDS PHMQDPNQAD EEANTQIIRV SGENBANK ID: B53771VERSION B53771 GI:21362961MAWALKLPLA DEVIESGLVQ DFDASLSGIG QELGAGAYSM SDVLALPIFK QEESSLPPDN61ENKILPFQYV LCAATSPAVK LHDETLTYLN QGQSYEIRML DNRELGELPE INGKLVKSIF121RVVFHDRRLQ YTEHQQLEGW RWNRPGDRIL DIDIPMSVGI IDPRANPTQL NTVEFLWDPA181KRTSVFIQVH CISTEFTMRK HGGEKGVPFR VQIDTFEENE NGEYTEHLHS ASCQIKVFKP241KGADRKQKTD REKNEKRTPH EKEKYQPSYE TTILTECSPN PEITYVNNSP SPGFNSSHSS301FSLGEGNGSP NHQPEPPPPV TDNLLPTTTP QEAQQWLHRN RFSTFTRLFT NFSGADLLKL361TRDDVIQICG PADGIRLFNA LKGRNVRPRL TIYVCQESLQ LEEQQQQQQQ QQQKHEDGDS421NGTFFVYHAI YLEELTAVEL TEKIAQLFSI SPCQISQIYK QGPTGIHVLI SDEMIQNFQE481EACFILDTMK QETNQSYHII LKGENBANK ID: M92299.1VERSION M92299.2. GI:184292MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAANHTGSYGYNYNGMDLSVNRSSASSSHEGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDNTCPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAEQPGENBANK ID: M68891.1VERSION M68891.1 GI:182995MEVAPEQPGWMAHPAVLNANDPDSERPGLAHNYMEPAHVLPPDEVDVFFNHLDSQGNPYYANPAEARAAVSYSPAHARLTGSQNCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKNNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGNPEPSSMVTANGGENBANK ID: XM_028606.2VERSION XM_028606.2 GI:15304625MDEMTAVVKIEKGVGGNNGGNGNGGGAFSQARSSSTGSSSSTGGGGQESQPSHLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGPMAGRSSLPPLGLPLPQRNRVAAVPMAAMAVSLPRIAQSLVGSMLCAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLVSSQASSSSFFTNANSYSTTTTTSNNGIMNFTTSGSSGTNSQGQIPQRVSGLQGSDALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQPQLVQGGQALQALQAAPLSGQTFTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSNQTLQLQNLQVQNPQAQTITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGTSGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGRRTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRANLRWHTGERPFNCTWSYCGKRFTRSDELQRHKRTNTGEKKFACPECPKRFNRSDHLSKHIKTHQNKKGGPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQVADLQSINISGNGFGENBANK ID: NP_009077.1DEFINITION HOMO SAPIENS ZINC FINGER PROTEIN 161 (ZNF161), MRNA.VERSION NB_007146.1 GI:6005967CDS 42..1592/CODON_START=41AGCGGGGGGA GTGGGGAGGA GGGGGGTCGG CCGCCGCAGC CATGGAGGCC AACTGGACCG61CGTTCCTGTT CCAGGCCCAT GAAGCTTCCC ATCACCAACA GCAGGCAGCA CAGAACAGCT121TGCTGCCCCT CCTGAGCTCT GCCGTGGAGC CCCCTGATCA GAAACCATTG CTTCCAATAC181CAATAACTCA GAAACCTCAG GGTGCACCAG AAACATTAAA GGATGCCATT GGGATTAAAA241AAGAAAAACC CAAAACTTCA TTTGTGTGCA CTTACTGCAG TAAAGCTTTC AGGGACAGCT301ATCACCTGAG GCGCCACGAA TCGTGCCACA CAGGGATCAA GTTGGTGTCC CGGCCAAAGA361AAACCCCCAC CACGGTGGTT CCCCTTATCT CTACCATCGC TGGGGACAGC AGCCGAACTT421CGTTGGTCTC GACCATTGCA GGCATCTTGT CAACAGTCAC TACATCTTCC TCGGGCACCA481ACCCCAGTAG CAGTGCCAGC ACCACAGCTA TGCCAGTGAC CCAGTCTGTC AAGAAACCCA541GTAAGCCTGT CAAGAAGAAC CATGCTTGTG AGATGTGTGG GAAGGCCTTC CGAGATGTGT601ACCATCTCAA TCGACACAAG CTCTCCCATT CAGATGAGAA ACCCTTTGAG TGTCCTATTT661GTAATCAGCG CTTCAAGAGG AAGGACCGGA TGACTTACCA TGTGAGGTCT CATGAAGGAG721GCATCACCAA ACCCTATACT TGCAGTGTTT GTGGGAAAGG CTTCTCAAGG CGTGACCACT781TAAGCTGTCA TGTAAAACAT GTCCATTCAA CAGAAAGACC CTTCAAATGC CAAACGTGCA841CTGCTGCCTT TGCCACCAAA GACAGACTGC GGACACACAT GGTGCGCCAT GAAGGCAAGG901TATCATGTAA CATCTGTGGG AAGCTCCTGA GTGCAGCATA CATCACCAGC CACTTAAAGA961CTCATGGGCA GAGCCAAAGT ATCAACTGTA ATACATGTAA ACAAGGCATC AGTAAAACAT1021GCATGAGTGA AGAGACCACT AACCAAAAGC AGCAGCAGCA GCAGCAGCAG CAACAACAAC1081AACAACAACA TGTGACAAGC TGGCCAGGGA AGCAAGTAGA AACACTCAGA CTGTGGGAAG1141AAGCTGTTAA AGCAAGGAAG AAAGAAGCTG CTAACCTGTG CCAAACCTCC ACGGCTGCTA1201CGACACCTGT GACTCTCACT ACTCCATTCA GTATAACATC CTCTGPGTCG TCTGAGACTA1261TGTCAAACCC AGTCACAGTG GCAGCTGCAA TGAGCATGAG AAGTCCACPA AATGTTTCAA1321GTGCAGTTAA CATAACCAGC CCAATGAACA TAGGGCATCC TGTAACTATA ACCAGTCCAT1381TATCCATGAC CTCTCCTTTA ACACTCACTA CCCCAGTCAA CCTCCCCACC CCCGTCACTG1441CCCCAGTGAA TATAGCACAC CCTGTCACCA TCACATCTCC AATGAATCTA CCCACACCTA1501TGACATTAGC CGCCCCTCTC AATATAGCAA TGAGACCTGT AGACAGCATG CCTTTCTTGC1561CCCAAGCTTT GCCTACATCA CCGCCTTGGT AAACAGTATT ATAAAATCAA AATATGGGTA1621AAAGTAAATA TTTACCAGCA ACTTAACTTT TAGTTGATTA AAGCAAAAAG TAAACCATGA1681AATTGGGAGA TTTTATTACA TTAGTTAATA AGAGTGTGGT AGCATTTTTC TCCAATTTGG1741CTGGGATTAT TCAAAGTAGG GTGTGTATGT AACTTATCAC TGGACCACTT TAGTTTAATC1801AGAAATTCCT TTTAGCTGAC AACATTGCTT AAACAGGATA GTAGTTGGCA AGATGAAATG1861CCAGAATTAA AACCAATCAT AAGTAGAACC CACTTCAAAA TAAAAAAACA GCATTACTAT1921TTCTAATCCC AAGGAATCAC TTTATTGTAA ACACTAGCAG AACTCTTCTC CCTATACAAG1981GTGGATGGCT GATTTTAACC TGAAATTTTA AATCCACAGA TTGAGAGCTA GTGTAGAATT2041GTCTGTGTTT ATTGTTTTTA TGAGTAAATA CATGCATTGT CATAATAAAA TGCATTTCAG2101AGAATATGCA TTTTACCTTT GGGAATATGT TAATTTCAGG CAGCATTCCC TATGGGAAAG2161GTGATACCAG CTCTGATATG CAAAGCATAT GATAATTTAT CATTCTAACT TCAACGTATA2221ATAGGGATTG TGACCTGATA TTTGGAGATG TAAATATTGC TCAGCATATT AATCCCGATG2281GAATATAGCA TTGTAGTTGA CTTTTTGENBANK ID: AAA36598.1DEFINITION HUMAN STEM CELL PROTEIN (SCL) MRNA, COMPLETE CDS.VERSION M29038.1 GI:337958CDS 81..725/CODON_START=11AGTCAGAGTC ACTTTCTGTA AATGGTACTT AGGTAGGCGC GTCCGCCTCG GTTACAGCGG61AGCTGCCCGG CGACGGCCGC ATGGTGCAGC TGAGTCCTCC CGCGCTGGCT GCCCCCGCCG121CCCCCGGCCG CGCGCTGCTC TACAGCCTCA GCCAGCCGCT GGCCTCTCTC GGCAGCGGGT181TCTTTGGGGA GCCGGATGCC TTCCCTATGT TCACCACCAA CAATCGAGTG AAGAGGAGAC241CTTCCCCCTA TGAGATGGAG ATTACTGATG GTCCCCACAC CAAAGTTGTG CGGCGTATCT301TCACCAACAG CCGGGAGCGA TGGCGGCAGC AGAATGTGAA CGGGGCCTTT GCCGAGCTCC361GCAAGCTGAT CCCCACACAT CCCCCGGACA AGAAGCTCAG CAAGAATGAG ATCCTCCGCC421TGGCCATGAA GTATATCAAC TTCTTGGCCA AGCTGCTCAA TGACCAGGAG GAGGAGGGCA481CCCAGCGGGC CAAGACTGGC AAGGACCCTG TGGTGGGGGC TGGTGGGGGT GGAGGTGGGG541GAGGGGGCGG CGCGCCCCCA GATGACCTCC TGCAAGACGT GCTTTCCCCC AACTCCAGCT601GCGGCAGCTC CCTGGATGGG GCAGCCAGCC CGGACAGCTA CACGGAGGAG CCCGCGCCCA661AGCACACGGC CCGCAGCCTC CATCCTGCCA TGCTGCCTGC CGCCGATGGA GCCGGCCCTC721GGTGATGGGT CTGGGCCACC AGGATCAGCC AGGAGGGCGT TCTTAGGCTG CTGGGATGGT781GGGCTTCAGG GCAGGTGGGG TGAGAATTGG GCGGCTCTGA AGCAAGGCGG TGGACTTGAA841CTTTCCTGGA TGTCTGAACT TTGGGAAGCC TTTACTGACC CTGGGGCTGG CTTTTCTGTT901TCCTGTACCA GTAGGAGAIC AGAAAAATGG AGCAAAGTGG TAGGTACTTT TTGTGAAGAC961GGCACGGTCT TCCCTCTTCC CTCAGTCCCA AATCCTTCCC AAGTAAGAGG CTGGAGTTGT1021CACTGCTTTT GGCCTGGAGT TTGGGATCCC TGTCTTTCCT AAGACCTGGG GTTGTCAGCT1081CTCATCTGAG GCATCCAGCA GTCTCTGCCT TGCCTTTAGC CCCTCCCAAG CTGGCTGGGG1141TGGCCTGTGT GGCCACTTCT GTCCATATTT ATAGGTACCC AATAGCTGCC CATTTCGTGA1201GCCCCATCTT CACCCAGGCC TATGTTGATC CATCCAGCTT GCCAGATGCT GCAGAGTCAC1261AAGCCTCGAG GTGCCTTCTT CAGGGCCTGG TTGAAGAAGA TGATCAGTGG ACAGTCTGCT1321CTAGATGAGC TGGGCCGGAG GGTCAGGAAA CCCAGTCGCC CTTACTTCTT GCCCTGGGGA1381TCAAAGTTCT GCTTTCTCCC CAATGAGACT TGCCTTCCTA AGCCTGTGGC TGTGGAGACC1441ATGTCTGCAG CCCTGAGAAA GCCCTGTCGG GCTTTGTGTG AAGGCAGAGA AAGGGACAAT1501GATACTAGAG TGATATGGAG CAAGAGATAT TTTGGGCATG TGGGCTTCAA CTCCTCGACA1561TCACTGTTCA TGCTGGCGAG TGAATGCCAG TGTGCTGATG GGCGTACGCT GGTGCTGAGT1621AGATGCGCAG CCCCATCTGT GCATTCTCCT GGATGCTTAG AGGGATTTCT TTGCTGTAAG1681ATGTCTGTTT GCTGATGGTC TGGTCTATGT TCCGAATTGA GCACAAAACC TGTCCTATGA1741ATGCTTTGCA TTTGGAATTT TTGCTTGACT TCAGTTATTG GTGGAATCTT TAGCGCTCAA1801TAGGACCAGG ATCCAGCCTC ACTTCTAGGG TATGGGAAAT CCAATCAGAG ACCAGGCCCT1861GGCTAAGACC CAAACATATG CACATTCACT TAGCAGAACC TTAAACACCC CTCAGTTGTG1921CAGCTTTTGG TCATCAAGGG TGCGTCTGGG AGGTTGGTTT AATGCAATAG AAGTGCTCCC1981CTCTGAAAGT TGTACATGAA ATTTTTGTAA ATCACATCCT TATCCTTCAT CTTTTAAAGA2041AATAACCACT GCAAGTCCTT TTGTAAAGTG AAGAATCCTT TTGTAGAATG AACCACTGCC2101CCTTCATTGA TTTCCTGTGT CAATCCAGAT GGTGGGATGT GGTTTTCTTA AGGTGAGGCC2161TGTCTGTGAC CTGCATCTAA GCCCATGGGA CAAATTGCAC AGAAGTCCTG TATGTCTGTC2221ATTGTACCCT TAAGTCACCC TAGCCCTCTC CCTCTAGGCT CTGCCTTCGA GGTCAGAGGA2281GAGATAGCCT GTGGCCCTGT CCTGCCATGC AAGAACTCAT CACTGTGGCT GTCTGGAAAG2341CCCCCCCTTA TAGTTTGGGC TTCAGCCTAG TGGCTTGTCC TGACCATGAT GGGGCCCTAA2401TTCAGCCATG TACAGACAGA GAATATGTCT GCTCCTTTCC CCTTCCTTTT AAGTAAGGTC2461CAATTCTCGA GCTTGGGGCA ACATTGTTCA CCTTTGTAGC ACTCAGGCTC TCCATTCAAT2521TTCAGGCTCC CCAGATCATG TTTTGGTGAA AATTAGGGTT GGTTCCTTTC CAACGTTTGG2581AAGATCCTGT GAGGAGCCCC ATCTGTCTAA AGATAGAGTC ATTGCTGTAG GATCTAAGGC2641TGTTTGCTTC ACCGTGGATT CGCTTGAGTT AGGAATGAGA ACTACCGACA GTATGGATGG2701GTGGATGGGT TTTATGAGAT GGATCACATA TTTTATTAAG AACTCAAACT TCTGGCTCCC2761TCTTCTTTCA GACTTGCCAT GTGACTCTGG CTTGGCCTAT CTCCTAGGGC TATGGTGTGG2821ACTGAATGGG ATCATGAAAG TAGACAGTTT TGAGAACGTA AAGAACTTTT TCTTTTCCCT2881CAATCTCAAT CCTGCAGTGG GGTTTCGCAG CCTGAGTCCA CGACCTAGGC AGTAGGCCGG2941TGTGCCTGAC TGCCCAGCAT TTGGGTAATT TAGATTGTAA ACCGCTTTGG CCTGAGTTAT3001TGAGATTGTC CTCATTTCTC CAGATTATCT ATTTGTGTGT GTGTGTGTGT GTGTGTGAGA3061GACGGTGTCT TGTTCTGTCA CTCAGGCTGG AGTACAGTGG TGCCATCATT GCTGTCTGCA3121GCCTTGAACT CTGGGCTCAA GCAATCCTCT CACCTCAGCC TCCCGAGTAG GGAGGACCAC3181AGGTGTGAGC CACCACACCT GGCTAATTTT TACTTTTTTT TTTTTTTGGT AGAGATGGAG3241TCTTGCTATA TTGCCCAGGC TGGTCTTGAA GTCCTGGCTT CAGGCAATTC TCCTGCCTTT3301GCCTCCAGAA GCACTGGGAT CACAGGTGTC AGCCATTGCA CCCAGCCCAG ATTGTCTTAA3361TTTCTATCTT GTTCCAAGGC CAGGGACAGT AATAAGAATG GAAAAGAGAT ATGGGAACAC3421TGGCAGACTG TGTAAAATGT AATGCAACTA CCCAAAACAA GCCTGGTAGG AAAGGGCAAG3481TCTTTAGGTC TTTGTAAGAA CTAAAGAAGA TCTGTAATTT TTATTTTCAC CCTCTGTACC3541CCATGACCTT ATCCTTCCTC TCCTTCCTTG TTACCCATGA AAAACTGGCA ACATTCCAAG3601AATAGCATCT GTACAAAGGG GAAAGAACAT AAAGGTAAAA CAAAACAAAA CAACATTTTG3661AGAACRAAGA TGACCATAAC CACTGAAGGG AATCACATCT TTTAAGACAA ATTCATATTC3721TTTTATTTGT TATGGCAGAT GACAAGATGG TACAACCTTT ATTCTTTTCC AAAATAAAAC3781AAAGGGCACA GCATCTGTAG TCAGCCGACA ACTCTTTCGG CCTTTTGGGG GTGGGTCTGG3641CCGTACTTGT GATTTCGATG GTACGTGACC CTCTGCTGAA GACTTGCCCC CTGCCCGTGT3901ACATAGTGCA TTGTTTCTGT GGGCGGGCCC AGCACTTTCC GTCAACGTTG TACTGTATGT3961GATGAATTGC GTTGGTCTCT GCATTTTTCT GCAGAAGAGG AGTAACCGCT CCAGGTACCT4021TGACCTTTGT ACAGGCCAGA GGCCAACACT GTGGGTGTGT GACTCTTTAG CAAAAAAAAC4081CCATGTGGTG ATGATGTGTC TATATATGTG AGGATGTATC GGGAAGATTT CTAAATAAAA4141GTTTTACAAA GGGGENBANK ID: NP_006168DEFINITION HOMO SAPIENS NEURAL RETINA LEUCINE ZIPPER (NRL), MRNA.VERSION NM_006177.1 GI:5453801CDS 118..831/CODON_START=11CCAGGCCCTG CTCCATGGAG CCTTCAGTCT CCTGGGAAGC TGTGCCTGTC TGGCTCTGGC61ACTGACCACA TCCTCTCGGC CATTTCTGAA GTGCACTCCT CCCAGCCCAG CTCCAGAATG121GCCCTGCCCC CCAGCCCCCT GGCCATGGAA TATGTCAATG ACTTTGACTT GATGAAGTTT181GAGGTAAAGC GGGAACCCTC TGAGGGCCGA CCTGGCCCCC CTACAGCCTC ACTGGGCTCC241ACACCTTACA GCTCAGTGCC TCCTTCACCC ACCTTCAGTG AACCAGGCAT GGTGGGGGCA301ACCGAGCGCA CCCGGCCAGG CCTGGAGGAG CTGTACTGGC TGGCTACCCT GGAGGAGGAG361CTGGGGGCTG GGGAGGCATT GGGGCTGAGT CCTGAAGAGG CCATGGAGCT GCTGCAGGGT421CAGGGCCCAG TCCCTGTTGA TGGGGCCGAT GGCTACTACC CAGGGAGCCC AGAGGAGACA481GGAGCCCAGC ACGTCCAGCT GGCAGAGCGG TTTTCCGACG CGGCGCTGGT CTCGATGTCT541GTGCGGGAGC TAAACCGGCA GCTGCGGGGC TGCGGGCGCG ACGAGGCGCT GCGGCTGAAG601CAGAGGGGGC GCACGCTGAA GAACCGCGGC TACGCGCAGG CCTGTCGCTC CAAGCGGCTG661CAGGAGGGGG GCGGGCTGGA GGCCGAGCGC GCCCGCCTGG CCGCCCAGCT GGACGCGCTG721CGGGCCGAGG TGGCCCGCCT GGCCCGGGAG CGCGATCTCT ACAAGGCTCG CTGTGACCGG781CTAACCTCGA GCGGCCCCGG GTCCGGGGAC CGCTGCCACG TCTTCCTCTG AGCCGTTCAG841AGCACCTTGT GGTGTAGTGG GGGCTGGGTG GGGTGGCTCC GCCCAGGAGG CGGCTGCACG901GTTCTCTGCA TCGTTACCAG AGCGCCTTCT GGTCCTAGCC ACGCCCTGTA TGACCGCGCA961AATATCCCCA AAGCTTTTGG GTCCTCAAGT CATGCCCGAA TTTAGATGCT GGTCATTTTC1021TGGAGAGGGG TCCCCTCCCC TTACGAACAC AAAAACCCAG CCCACATGAC TAGCACGCTG1081AGCTCTGCAG GGACCAGTGC CAGGCACTGG GGGGTGGAAG TGTGGTGACA CAGTGAATGG1141GAGGTGGAGG AGGGTTGCAG CTCCCACCTC AGTTTAGTTT TTAATTCAGG GTTTTCAACC1201TGTAACACAT TAAAGCTGTA ATTAGCAATG AGGCTGTATT TTCATTCTGA AGCTTGTAAC1261CTCCCCATTT TAGCACTACA GAATTTTCAA GATTTCAATA TCCAACAACT AGATAGATTA1321GGACCTCTAT CGGAGATGCT TTTTCCCTGC CCAACCCTGT GGCCTTCAGG GCTCAGAGCA1381GCAAAGGCCT GAAGAGTGAG CTCTGGGGGT TGTTGGTGTG GGTTGGGAGA GAGCTGTGTG1441CAGAAGTCTG GAAACCTGGG TCCTAGTCCC AGCTCTTCCA TGGGATCCCC CTGTCACCCT1501GAGCAAATCA GTTGCTTCCT GGACTTGTGT TACTTCATCT AATTCTCATG TGGATTGGAC1561GACTTCTCCT CCCTTTCCAG TTCTGGCATC TCCCCAGTAT GGAAGTCCCG GTGGTCTCCC1621CAAGAAGTCC CCAAGACAAT CTCGCCAAAG GCACCTCCTA TCCTCCTGCA GTTTCCCACC1681TGCAGCCTAG GCAGGGCATG CACAGCCCAG GCGAGGAAGC CTGCCTTCTC TGTGAGCACA1741TACGTGGGTC CTCCGCAGCT CCCTCCAGCC TGTCTGGGCC TCCAGACCTG CACAGGGTGC1801TCCTGCCACC TCCCACCTCT CTGAGGGCTG AGGTGAGACT TCTCCTGGGA TGACAATTTG1861CTGAGAGAGT GCAGCTTTTC TGAATTAAAC TTGAAGTCCA CGCAGAATTC TAATGCAATA1921AGCTAAATGT TGENBANK ID: AAA58399.1VERSION M95809.1 GI:179568/GENE=“BTF2”CDS 55..1701/CODON_START=11AGTTAGTTAC TTCCTGTCTA GAGTTGTAGC TTCCACCTGC ACCTTCTAGC CACCATGCCA61ACCTCATCTG AAGAAGTTTT GCTGATTGTA AAGAAAGTGC GTCAAAAGAA GCAGGATGCA121GCTCTGTACC TCATGGCAGA AAGAATTGCT TGGGCACCTG AAGGCAAAGA TAGATTTACA181ATCAGCCATA TGTATGCAGA TATTAAATGC CAGAAAATTA GTCCAGAAGG AAAAGCTAAA241ATTCAGCTTC AGCTGGTCCT ACATGCAGGG GACACAACTA ACTTCCATTT TTCCAATGAA301ACCACACCAG TGAAAGAGCG AGATGCAGTA AAAGACCTTC TTCAGCAGCT GCTGCCCAAA361TTCAAGAGGA AAGCAAATAA AGAACTGGAA GAGAAGAACA GAATGCTGCA AGAAGATCCT421GTTTTGTTTC AGCTTTATAA AGACCTTGTT GTGAGTCAAG TGATCAGTGC TGAGGAATTC481TGGGCCAATC GTTTAAATGT GAATGCAACA GATAGTTCTT CCACATCCAA TCATAAGCAG541GATGTTGGCA TTTCTGCTGC ATTTCTGGCT GATGTCCGGC CCCAAACTGA TGGCTGTAAC601GGTCTAAGAT ATAATTTAAC TTCTGATATC ATTGAGTCCA TATTTAGGAC CTATCCAGCA661GTAAAAATGA AATATGCAGA AAATGTTCCC CACAACATGA CAGAGAAGGA ATTCTGGACA721CGTTTTTTCC AGTCCCATTA TTTTCACAGG GATCGGCTGA ATACAGGGTC AAAGGATCTC781TTTGCAGAAT GTGCCAAAAT AGATGAAAAA GGCCTAAAAA CAATGGTTTC ATTAGGAGTG841AAAAACCCAC TACTAGATTT AACAGCTTTG GAAGATAAAC CATTAGATGA GGGCTATGGC901ATTTCCTCTG TGCCATCTGC TTCCAATTCT AAATCCATAA AAGAGAATAG TAATGCTGCC961ATCATCAAGA GATTTAACCA TCACAGTGCC ATGGTCCTGG CAGCTGGACT CAGAAAACAA1021GAAGCACAAA ATGAACAAAC TAGTGAGCCC AGCAACATGG ATGGAAATTC CGGAGATGCA1081GACTGCTTTC AGCCAGCAGT CAAAAGGGCG AAATTACAAG AGTCCATTGA ATATGAAGAC1141TTGGGGAAAA ATAATTCTGT AAAAACGATT GCACTAAACC TCAAGAAGTC AGATAGGTAT1201TATCATGGTC CAACTCCAAT CCAGTCACTA CAGTATGCAA CAAGTCAGGA CATTATTAAT1261TCTTTTCAAA GTATTAGACA AGAAATGGAA GGTTATACAC CCAAGTTAAC TCAGGTTCTC1321TCAAGTAGTG CTGCCAGTAG TACCATCACA GCACTGTCAC CTGGAGGGGC ACTTATGCAG1381GGAGGAACAC AGCAAGCCAT AAACCAGATG GTGCCAAATG ATATTCAATC TGAATTGAAA1441CACTTATATG TAGCTGTTGG AGAACTTCTA CGACATTTCT GGTCCTGCTT TCCTGTTAAT1501ACGCCATTCC TAGAAGAAAA GGTAGTGAAA ATGAAAAGTA ATTTGGAACG ATTCCAAGTT1561ACGAAGCTCT GTCCATTCCA AGAAAAGATT CGGAGACACT ATTTAAGCAC AAATTTGGTA1621AGTCACATAG AAGAGATGCT CCAGACAGCC TACAACAAGC TCCACACATG GCAGTCACGG1681CGTCTGATGA AGAAAACGTG AGGTGGCCAT GATGCTTACA GGTTTTGTGA GATTGAGAGA1741ACTATGACCT GCAGCAACTC TGGAAACCTG GCCTGACAGA CAAGCAGATG ACCTCACAGG1801AGTGATAAGA AACATCTGCT CCACGCCAAC TCCCAGAGCT GATGCTATTG TACTTGCACA1861TTGGAGACTG AAAGGAAAGA AGGGACTAAA TGCGENBANK ID: AAA65605.1DEFINITION HUMAN OCTANER BINDING TRANSCRIPTION FACTOR 1 (OTF1) MRNA,VERSION L20433.1 GI:418015CDS 235..1497/CODON_START=11GCGGGGCTAG AGCTGTCGGA GAAGCGGGAC CGCGAGGCCG GCGCGCGGCG CTCTGCGCGG61TCAGAGGGAG CGCCTGGCAG CAGCAGGAGC AGCAGCAGCA GCCCGCGGCG GGGCCGCCGC121CAGCCGCCGC GACCGCCGCG GCTGCAGCCT CCGAAGGGAG GCCGGGTGAG CCGGCGTACG181CACTTTCCCG CGGACTTTCG GAGTGTTTGT GGATATACAT GCCAAGCCGC CACGATGATG241TCCATGAACA GCAAGCAGCC TCACTTTGCC ATGCATCCCA CCCTCCCTGA GCACAAGTAC301CCGTCGCTGC ACTCCAGCTC CGAGGCCATC CGGCGGGCCT GCCTGCCCAC GCCGCCGCTG361CAGAGCAACC TCTTCGCCAG CCTGGACGAG ACGCTGCTGG CGCGGGCCGA GGCGCTGGCG421GCCGTGGACA TCGCCGTGTC CCAGGGCAAG AGCCATCCTT TCAAGCCGGA CGCCACGTAC481CACACGATGA ACAGCGTGCC GTGCACGTCC ACTTCCACGG TGCCTCTGGC GCACCACCAC541CACCACCACC ACCACCACCA GGCGCTCGAA CCCGGCGATC TGCTGGACCA CATCTCCTCG601CCGTCGCTCG CGCTCATGGC CGGCGCGGGC GGCGCGGGCG CGGCGGCCGG CGGCGGCGGC661GCCCACGACG GCCCGGGGGG CGGTGGCGGC CCGGGCGGCG GCGGCGGCCC GGGCGGCGGC721GGCCCCGGGG GAGGCCGCGC TGGCGGCCCG GGGGGCGGCG GCGGCGGCCC GGGCGGCGGG781CTCCTGGGCG GCTCCGCGCA CCCTCACCCG CATATGCACA GCCTGGGCCA CCTGTCGCAC841CCCGCGGCCG CCGCCGCCAT GAACATGCCG TCCGGGCTGC CGCACCCCGG GCTGGTGGCG901GCGGCGGCGC ACCACGGCGC GGCAGCGGCA GCGGCGGCGG CGTCGGCCGG GCAGGTGGCA961GCGGCATCGG CGGCGGCGGC CGTCGTGGCC GCAGCGGGCC TGGCGTCCAT CTGCGACTCG1021GACACGGACC CGCGCCAGCT CCAGGCCTTC GCGGAGCGCT TCAAGCAGCG GCGCATCAAG1081CTGGGCGTGA CGCAGGCCGA CGTGGGCTCG GCGCTGGCCA ACCTCAAGAT CCCGGGCGTG1141CGCTCACTCA GCCAGAGCAC CATCTGCAGG TTCGAGTCGC TCACGCTCTC GCACAACAAC1201ATGATCGCGC TCAAGCCCAT CCTGCAGGCG TGGCTCCAGG AGGCCGAGGG CCCCCAGCGC1261GAGAAAATGA ACAAGCCTGA GCTCTTCAAC GGCGGCGAGA AGAAGCGCAA GCGGACTTCC1321ATCGCCGCGC CCGAGAAGCG CTCCCTCGAG GCCTACTTCG CCGTGCAGCC CCGGCCCTCG1381TCCGAGAAGA TCGCCGCCAT CGCCGAGAAA CTGGACCTCA AAAAGAACGT GGTGCGGGTG1441TGGTTTTGCA ACCAGAGACA GAAGCAGAAG CGGATGAAAT TCTCTGCCAC TTACTGAGGG1501GGCTGGGAGG TGTCGGGCGG GACAGAATGG GGAGCTGAGG AGGCATTTTT GGGGGGCTTT1561CCTCTGCTTG CCTCCCCTCG GATTTGGAGT GTCCGTTATC CTGCCTGCAT TTGGGGAGTC1621CCTTCTCGCT CTCTTTCCTC CACCCATTCT CTGATTTTCC TGCCTTTGCT GTCCCCTAGC1681CTTGAGGACT GGGGTGCTGG GTGTGGGGAT TGGAGTATAG GGTAGGGGAG AAGGGGGGGA1741GCATTCGGGG GAGTGGGGAG TGGGGGGAAG GAAAGCGGAG ACCGGACCAG GGGTTTTAAG1801GAGCAGGATG GTTCTGGGGT TTGGGTGGGG GGAGACGCGG GAAGGGTAGG AAAATGGACT1861GTTTCTGACC AGAGACACTT ACCTAAATAT CCTGGGGACC AAGGAACTAT GTACAAAAAC1921AAACCTACCA ACCACCAAAA ACTAGACAAA TAAAGACAAA CTAAAACAAA ACAGAACAAA1981AGCAAAGGAA AATGCTTTAG AAATTTTAAC TCCGGGGAGC CATAATCTGC AACTTCATTT2041TCCCCCATAG AAGAGAAAAA AGACCACCAC CATTATTACG ACCTCCCCAA CCCTACACGC2101ACGAACTGAG TCGAAAAACG AAAACCAAAC GAGCGAGAAG TTGAAGTTCT GGGTATCAAA2161GCTAGTTGTT CTGTCTGCGT GTTTAATTTT TCCCTCTCTC ACCTCCACCC CATCCATATC2221CTCTTTATTT CCTCCGTTCC AATGAGAGGC CTATGGCTGC TCTCCAATCC CGGGAAGTGA2281GTGGGAGCAC AGCTGAAAAG AGAGGGTCAG GGGGAGGCTG GCTGCTTGCT TAGGTGGAAT2341CCAACTTTTC CCGTGGCCCT GCCTATACTC TGGTGGCCTG GTCCTGTTGG GGTGGGGGTC2401TTTGGAGAGA AGGGCATAGT CTTTGAGCTA CTAAAAAGCA GAATTCCGGA GCTTCGAGAT2461ATCTTATTCT AGGAAAATGA AACAATTTTA ACAACAGTTT TTTTTCCTCT TATGTCGAAG2521ATCTAGTTTT AGACAATTTC AAAATAAGCT TTTCCCACTC ATAGAACTTT AACTTGCCCT2581TTCAGTTTTA TCTTTTTTTT AGAGAGAGGT TTAAACTACT GATTTTTCCT GTTGATTCAA2641ATAGACTAAT GGGGTGAAAG TTATTAGGAG AGATACTGTC TCCTGTTTTC TCCACTGAAC2701GAGACTCATC TTGCTCTTCT AGGTCCCGTT TCTTCCTCTC TTGGAGGACA TGAAATTATA2761GAAATGTTGA GAAGTTCCTG CTTTCTTTTG CGGTAGGACT TGGCTGTGAG AAAATCACCT2821AAATCCCAGA AAAGAGGAAG ACAGATTTAA AGTGCCCCCA CCCCCATTTG TTTCAAAGAG2881GTCTGCATGT TGGGCGAAAA CAGAACAACT GTGTTTCCTT TTACTTGTTC TTATTATTCA2941AGAGTCATTT ATTACAGGGG ATAAATGTTG GGTAGCAAGA ACTTTAATTT GCACTACCAG3001TCTCCCAAAT AGAAAATCAT GTATAGTATT TCATAGTAAT AATCAGGTAC CTTACAAGCT3061GCTGGTGGAT TTTAAAAAAT TAAGATAGTT GAAGGTGGTT AGGTAAAATG CCTGCTTTGT3121GTACAAGATA CTCTTTGGAT CTCTCGTAGA GATGGTTTGT TACCATCCTT TAATCATAAC3181TAAAACATTG AAAACAGAAC AAATGAGAAA AGAAAAAAAA CCTGCCGATT AACAAGACTG3241AAATCATGCA TGATCTGAAA GGTGTGGAAA GAAACACAAT TAGGTCTCAC TCTGGTTAGG3301CATTATTTAT TTAATTATGT TGTATATCAT TGTTTGCAGG GCAAACATTC TATGCATTTG3361AAACTGAGCA CTAAACTGGG CTAGCTTTCT GGTAGACCGT TTTGTGGCTA GTGCGATTTC3421ACAGTCTACT GCCTGTTTCC ACTGAAAACA TTTTTGTCAT ATTCTTGTAT TCAAAGAAAA3481CAGGAAAAAA GTTATTGTAA ATATTTTATT TAATGCACAC ATTCACACAG TGGTAACAGA3541CTGCCAGTGT TCATCCTGAA ATGTCTCACG GATTGATCTA CCTGTCTATG TATGTCTGCT3601GAGCTTTCTC CTTGGTTATG TTTTTTCTCT TTTACCTTTC TCCTCCCTTA CTTCTATCAG3661AACCAATTCT ATGCGCCAAA TACAACAGGG GGATGTGTCC CAGTACACTT ACAAAATAAA3721ACATAACTGA AAGAAGAGCA GTTTTATGAT TTGGGTGCGT TTTTGTGTTT ATACTGGGCC3781AGGTCCTGGT AGAACCTTTC AACAAACAAC CAAACAAAAA AAAAGENBANK ID: AAA61146.1DEFINITION HUMAN TRANSCRIPTION FACTOR (E2A) MRNA, COMPLETE CDS.VERSION M31523.1 GI:339477CDS 31..1995/CODON_START=11GCCTGAGGTG CCCGCCCTGG CCCCAGGAGA ATGAACCAGC CGCAGAGGAT GGCGCCTGTG61GGCACAGACA AGGAGCTCAG TGACCTCCTG GACTTCAGCA TGATGTTCCC GCTGCCTGTC121ACCAACGGGA AGGGCCGGCC CGCCTCCCTG GCCGGGGCGC AGTTCGGAGG TTCAGGTCTT181GAGGACCGGC CCAGCTCAGG CTCCTGGGGC AGCGGCGACC AGAGCAGCTC CTCCTTTGAC241CCCAGCCGGA CCTTCAGCGA GGGCACCCAC TTCACTGAGT CGCACAGCAG CCTCTCTTCA301TCCACATTCC TGGGACCGGG ACTCGGAGGC AAGAGCGGTG AGCGGGGCGC CTATGCCTCC361TTCGGGAGAG ACGCAGGCGT GGGCGGCCTG ACTCAGGCTG GCTTCCTGTC AGGCGAGCTG421GCCCTCAACA GCCCCGGGCC CCTGTCCCCT TCGGGCATGA AGGGGACCTC CCAGTACTAC481CCCTCCTACT CCGGCAGCTC CCGGCGGAGA GCGGCAGACG GCACCCTAGA CACCCAGCCC541AAGAAGGTCC GGAAGGTCCC GCCGGGTCTT CCATCCTCGG TGTACCCACC CAGCTCAGGT601GAGGACTACG GCAGGGATGC CACCGCCTAC CCGTCCGCCA AGACCGCCAG CAGCACCTAT661CCCGCCCCCT TCTACGTGGC AGATGGCAGC CTGCACCCCT CAGCCGAGCT CTGGAGTCCC721CCGGGCCAGG CGGGCTTCGG GCCCATGCTG GGTGGGGGCT CATCCCCGCT GCCCCTCCCG781CCCGGTAGCG GCCCGGTGGG CAGCAGTGGA AGCAGCAGCA CGTTTGGTGG CCTGCACCAG841CACGAGCGTA TGGGCTACCA GCTGCATGGA GCAGAGGTGA ACGGTGGGCT CCCATCTGCA901TCCTCCTTCT CCTCAGCCCC CGGAGGCACG TACGGCGGCG TCTCCAGCCA CACGCCGCCT961GTCAGCGGGG CCGACAGCCT CCTGGGCTCC CGAGGGACCA CAGCTGGCAG CTCCGGGGAT1021GCCCTCGGCA AAGCACTGGC CTCGATCTAC TCCCCGGATC ACTCAAGCAA TAACTTCTCG1081TCCAGCCCTT CTACCCCCGT GGGCTCCCCC CAGGGCCTGG CAGGAACGTC ACAGTGGCCT1141CGAGCAGGAG CCCCCGGTGC CTTATCGCCC AGCTACGACG GGGGTCTCCA CGGCCTGCAG1201AGTAAGATAG AAGACCACCT GGACGAGGCC ATCCACGTGC TCCGCAGCCA CGCCGTGGGC1261ACAGCCGGCG ACATGCACAC GCTGCTGCCT GGCCACGGGG CGCTGGCCTC AGGTTTCACC1321GGCCCCATGT CGCTGGGTGG GCGGCACGCA GGCCTGGTTG GAGGCAGCCA CCCCGAGGAC1381GGCCTCGCAG GCAGCACCAG CCTCATGCAC AACCACGCGG CCCTCCCCAG CCAGCCAGGC1441ACCCTCCCTG ACCTGTCTCG GCCTCCCGAC TCCTACAGTG GGCTAGGGCG AGCAGGTGCC1501ACGGCGGCCG CCAGCGAGAT CAAGCGGGAG GAGAAGGAGG ACGAGGAGAA CACGTCAGCG1561GCTGACCACT CGGAGGAGGA GAAGAAGGAG CTGAAGGCCC CCCGGGCCCG GACCAGCCCA1621GACGAGGACG AGGACGACCT TCTCCCCCCA GAGCAGAAGG CCGAGCGGGA GAAGGAGCGC1681CGGGTGGCCA ATAACGCCCG GGAGCGGCTG CGGGTCCGTG ACATCAACGA GGCCTTTAAG1741GAGCTGGGGC GCATGTGCCA ACTGCACCTC AACAGCGAGA AGCCCCAGAC CAAACTGCTC1801ATCCTGCACC AGGCTGTCTC GGTCATCCTG AACTTGGAGC AGCAAGTGCG AGAGCGGAAC1861CTGAATCCCA AAGCAGCCTG TTTGAAACGG CGAGAAGAGG AAAAGGTGTC AGGTGTGGTT1921GGAGACCCCC AGATGGTGCT TTCAGCTCCC CACCCAGGCC TGAGCGAAGC CCACAACCCC1981GCCGGCCACA TGTGAAAGGT ATGCCTCCGT GGGACGAGCC ACCCGCTTTC AGCCCTGTGC2041TCTGGCCCCA GAAGCCGGAC TCGAGACCCC GGGCTTCATC CACATCCACA CCTCACACAC2101CTGTTGTCAG CATCGAGCCA ACACCAACCT GACAAGGTTC GGAGTGATGG GGGCGGCCAA2161GGTGACACTG GGTCCAGGAG CTCCCTGGGG CCCTGGCCTA CCACTCACTG GCCTCGCTCC2221CCCTGTCCCC GAATCTCAGC CACCGTGTCA CTCTGTGACC TGTCCCATGG ATCCTGAAAC2281TGCATCTTGG CCCTGTTGCC TGGGCTGACA GGAGCATTTT TTTTTTTTCC AGTAAACAAA2341ACCTGAAAGC AAGCAACAAA ACATACACTT TGTCAGAGAA GAAAAAAATG CCTTAACTAT2401AAAAAGCGGA GAAATGGAAA CATATCACTC AAGGGGGATG CTGTGGAAAC CTGGCTTATT2461CTTCTAAAGC CACCAGCAAA TTGTGCCTAA GCGAAATATT TTTTTTAAGG AAAATAAAAA2521CATTAGTTAC AAGATTTTTT TTTTCTTAAG GTAGATGAAA ATTAGCAAGG ATGCTGCCTT2581TGGTCTCTGG TTTTTTTAAG CTTTTTTTGC ATATGTTTTG TAAGCAACAA ATTTTTTTGT2641ATAAAAGTCC CGTGTCTCTC GCTATTTCTG CTGCTGTTCC TAGACTGAGC ATTGCATTTC2701TTGATCAACC AGATGATTAA ACGTTGTATT AAAAAGACCC CGTGTAAACC TGAGCCCCCC2761CCGTCCCCCC CCCCGGAAGC CACTGCACAC AGACAGACGG GGACAGGCGG CGGGTCTTTT2821GTTTTTTTGA TGTTGGGGGT TCTCTTGGTT TTGTCATGTG GAAAGTGATG CGTGGGCGTT2881CCCTGATGAA GGCACCTTGG GGCTTCCCTG CCGCATCCTC TCCCCTCAGG AAGGGGACTG2941ACCTGGGCTT GGGGGAAGGG ACGTCAGCAA GGTGGCTCTG ACCCTCCCAG GTGACTCTGC3001CAAGCAGCTG TGGCCCCAGC GGTACCCTAC ACAACGCCCT CCCCAGGCCC CCCTAAGCTG3061CTCTCCCTTG GAACCTGCAC AGCTCTCTGA AATGGGGCAT TTTGTTGGGA CCAGTGACCC3121CTGGCATGGG GACCACACCC TGGAGCCCGG TGCTGGGGAC CTCCTGGACA CCCTGTCCTT3181CACTCCTTGC CCCAGGGACC CAGGCTCATG CTCTGAACTC TGGCTGAGAG GAGTCTGCTC3241AGGAGCCAGC ACAGGACACC CCCCACCCCA CCCCACCATG TCCCCATTAC ACCAGAGGGC3301CATCGTGACG TAGACAGGAT GCCAGGGGCC TGACCAGCCT CCCCAATGCT GGGGAGCATC3361CCTGGCCTGG GGCCACACCT GCTGCCCTCC CTCTGTGTGG TCCAAGGGCA AGAGTGGCTG3421GAGCCGGGGG ACTGTGCTGG TCTGAGCCCC ACGAAGGCCT TGGGCTGTGG CTCCGACCCT3481GCTGCAGAAC CAGCAGGGTG TCCCCTCGGG CCCATCTGTG TCCCATGTCC CAGCACCCAG3541GCCTCTCTCC AGGTCTCCTT TTCTGGTCTT TTGCCATGAG GGTAACCAGC TCTTCCCAGC3601TGGCTGGGAC TGTCTTGGGT TTAAAACTGC AAGTCTCCTA CCCTGGGATC CCATCCAGTT3661CCACACGAAC TAGGGCAGTG GTCACTGTGG CACCCAGGTG TGGGCCTGGC TAGCTGGGGG3721CCTTCATGTG CCCTTCATGC CCCTCCCTGC ATTGAGGCCT TGTGGACCCC TGGGCTGGCT3781GTGTTCATCC CCGCTGCAGG TCGGGCGTCT CCCCCCGTGC CACTCCTGAG ACTCCACCGT3841TACCCCCAGG AGATCCTGGA CTGCCTGACT CCCCTCCCCA GACTGGCTTG GGAGCCTGGG3901CCCCATGGTA GATGCAAGGG AAACCTCAAG GCCAGCTCAA TGCCTGGTAT CTGCCCCCAG3961TCCAGGCCAG GCGGAGGGGA GGGGCTGTCC GGCTGCCTCT CCCTTCTCGG TGGCTTCCCC4021TGCGCCCTGG GAGTTTGATC TCTTAAGGGA ACTTGCCTCT CCCTCTTGTT TTGCTCCTGC4081CCTGCCCCTA GGTCTGGGTG GCAGTGGCCC CATAGCCTCT GGAACTGTGC GTTCTGCATA4141GAATTCAAAC GAGATTCACC CAGCGCGAGG AGGAAGAAAC AGCAGTTCCT GGGAACCACA4201ATTATGGGGG GTGGGGGGTG TGATCTGAGT GCCTCAAGAT GGTTTTCAAA AAATTTTTTT4261TAAAGAAAAT AATTGTATAC GTGTCAACAC AGCTGGCTGG ATGATTGGGA CTTTAAAACG4321ACCCTCTTTC AGGTGGATTC AGACACCTGT CCTGTATATA ACACCACTGT AGCAATAAAC4381GTGACATTTT ATAAAGGENBANK ID: NM_000416.1VERSION NM_000416.1 GI:4557879MALLFLLPLVMQGVSRAENGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVFVFTVEVKNYCVKNSENIDACTNISHHYCNISDNVCDPSNSLWVRVKARVCQKESAYAKSEEFAVCRDCKIGPPKLDIRKEEKQINIDIFHFSVFVNCDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEGDCDEIQCQLAIPVSSLNSQYCVSAEGVLEVWCVTTEKSKEVCITIFNSSIKCSLWIPVVAALLLWLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKPESKYVSLITSYQPFSLEKEVVCEEFLSPATVPGMHTEDNPCKVEHTEELSSITEVVTTEENIPDVVPGSELTPIERESSSPLSSNQSEPGSIALNSYESRNCSESDHSRNGFDTDSSCLESHSSLSDSEFPPNNKCEIKTEGQELITVIKAPTSFGYDKFHVLVDLLVDDSGKESLIGYRPTEDSKEFSGENBANK ID: M27492.1VERSION M27492.1 GI:186289MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPCPLNPNEHKGTITWYKDDSKTPVSTEQASRIMQHKEKLWFVFAKVEDSGHYYCVVRNSSYCLRIKISAKEVENEPNLCYNAQAIFKQKLPVAGDGCLVCPYMEFFKNENNELPKLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKFTRPVIVSPANETNEVDLGSQIQLICNVTGQLSDIAYNKWNGSVIDEDDPVLGEDYYSVENPANKRRSTLITVLNISEIESRFYKNPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVCEGSTSDCDIWVFKVLPEVLEKQCGYKLFIYCRDDYVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSEEQIANYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWSCDFTQGFQSAKTRFWKNVRYHMFVQRRSPSSKHQLLSPATKEKLQREAHVPLGGENBANK ID: L34059VERSION L34059.1 GI:506409MTACAGVLLLLLSLSCALRANNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPDKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIFPINVFENSRGPFFQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSINSMSGRNYVTRPMDREEHASYHLRAHAVDNNGNKVENPIDLYIYVIDMNDNHPEFINQVYNCSVDEGSKFGTYVMTITANDADDSTTANGMVRYRTVTQTPQSPSQNNFTINSETGDIVTVAAGWDREKVQQYTVIVQATDNEGNLNYGLSNTATAIITVTDVNDNPSEFTASTFAGEVPENSVETVVANLTVMDRDQPHSBNWNAVYRIISGDPSGHFSVRTDFVTNEGMVTVVKAVDYELNRAFNLTVNVSNQAPLASGIQNSFQSTAGVTISINDINEAPYFPSNHKLILEEGVPPGTVLTTFSIAVDRDRFMQQAVRYSKLSDPASWLHINATNGQITTVAVLDRESLYTKNNVYEATFLAADNCIFPAS0TGTLQIYLIDINDNAFELLPKEAQICERPNLNAINITAADADVHPNIGPYVFELPFVFAAVRKNWTITRLNCDYAQLSLRILYLEAGMYDVFIIVTDSGNPFLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVREKILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPCVRRVDERPVGFEFQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEEDGENSANK ID: M77640VERSION M77640.1 GI:186053MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVNEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSFHSQSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAFKWPKETVKPVEVEEGESVVLPCNPPPSAEFLRIYWMNSKILIHKQDERVTMGQNGNLYFANVLTSDNHSDYICHAEFFGTRTIIQKEPIDLRVKATNSNIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMFADRVTYQNENKTLQLLKVGEEDDGEYRCLAENSLGSAREAYYVTVEAAPYWLHKPQSHLY0PGETARLDCQVQGRPQPEVTWRINGIFVEELAKDQKYRIQRGALILSNVQPSDTNVTQCEARNRNGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTCRYFCLAANDQNNVTIMANLKVKDATQITQCFRSTIEKKGSRVTFTCQASFDPSLGPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSFGPVFRLVLSDLHLLTQSQVRVSWSFAEDHNAFIEKYDIEFEDKENAFEKWYSLGKVFGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAFEKNPVDVKGEGNETTNMVTTWKPLRWMDNNAFQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYFQAIPELEGIETLNSSAVLVKWRPVDLAQVKGELRGYNVTYWREGSQRKHSKRHIHKDHVVVFANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTESTPEGVFGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPELRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVFKEGQCNFRFEILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERIAFRHQNAVKTNGTGRVRLFFAGFATEGWFIGFVSAIILLLLVLLILCIKRSKGGKYSVKDKEDTQVDSEARPNKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVQVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALEGENBANK ID: M59911.1VERSION M59911.1 GI:186496MGPGPSRAPRAPRLMLCALALMVAAGGCWSAFNLDTRFLVVKEAGNPGSLFGYSVALERQTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCFLTAHKDDCERMNITVKNDPGEHIIEDNWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNENCNSNTDYLETGMCQLGTSGGFTQNTVYFGASGAYNWKGNSYNIQRKEWDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHCPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGERLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHKTLVPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAGSESAVFHGFFSNPENRCQKLELLLMDNLRDKLRPIIISMNYSLPLRNPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRNELLIAFEVTGVTLHTRDLQVQLQLSTSSHQDNLWPMTLTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPNGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTETTVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPFVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFTEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAETELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQPSETERLTDDYGENBANK ID: M81695.1VERSION M81695.1 GI:487829MTRTRAALLLFTALATSLGFNLDTEELTAFRVGSAGFGDSVVQYANSWVVVGAPQKITAANQTGGLYQCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNNYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATNMNFVRAVISQFQRPSTQFSLNQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDATKTLIVITDGKKEGDSLDYKDVTPMADAAGIIRYATGVGLAFQNRNSNKELNDTASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELENAQEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNNSPTFINMSQENVDNRDSYLGYSTELALWKGVQSLVLGAPRYQHTGKAVIFTQVSRQWRNKAEVTGTQTGSYFGASLCSVDVDTDGSTDLVLTGAPHYYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSNSQRTAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAETPRSAFECREQVVSEQTLVQSNTCLYIDKRSKNLLGSRDLQSSVTLDLALDPGELSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSCVEGSVTPTTLRLNFTLVGKPLLAFRNLRPMLAALAQRYFTASLPFEKNCGADHTCQDNLGISFSFPGLKSLLVGSNLELNAEVNVWNDGEDSYGTTITFSHPAGLSYRYVAEGGKQGQLRSLHLTCDSAPVGSQGTWSTSCRTNHLTFRGGAQTTFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLPVSTNFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCSTAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQTLQKKVSVVSVAETTFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLTVGSSTGGLLLLALITAVLYKVGFFKRQYKEMMEEANGQTAPENGTQTPSPPSEKGENBANK ID: X51841.1VERSION X51841.1 GI:33910MAGPEPSPWARLLLAALTSVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRRCNTQAELLAAGCQRESIVVMESSFQTTEETQTDTTLRRSQNSPQGLRVRLRPGFERHFELEVFEPLESPVDLYTLNDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSVPQTDMRPEKLKEFWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAILQTAVCTRDIGWRFDSTHLLVESTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYRTQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLEEAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTRTGSPHIRRGEVGIYQVQLRALEHVDGTHVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFVCGQCVCSEGWSGQTCNCSTGSLSDIQFCLREGEDKPCSGRGECQCCHCVCYGEGRYEGQFCEYDNFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLYTSTICEINYSATHPGLCEDLRSCVQCQAWGTCEKKGRTCEECNFKVKMVDELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFNWLIPLLLLLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLRSGNLKGRDVVRWKVTNNMQRPGFATHAASTNPTELVPYGLSLRLARLCTENLLKPDTRECAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTTVDTVLMAPRSAKPALLKLTEKQVEQRAFHDLKVAPGYYTLTADQDARGNVEFQEGVELVDVRVFLFIRPEDDDEKQLLVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQFEFSVSRGDQVARIPVTRRVLDCGKSQVSYRTQDGTAQENRDYTPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFGAHLGQPHSTTIIIRDEDELDRSFTSQMLSSQPPFHGDLGAPQNPNAKAAGSRKIHFNWLPPSGKPMCYRVKYNIQGDSESEAHLLDSKVFSVELTNLYPYCDYEMKVCAYGAQGEGEYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNREIGPMKKVLVDNPKNRMLLIENLRESQFYRYTVKARNGAGWGPEREAIINLATQPKRPMSIFIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDFAFPGSTNSLHRNTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGVFDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLNIFNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRFNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQVGGPFPQLGSRAGLFQHFLQSEYSSITTTHTSATEPFLVDGPTLGAQHLEACGSLTRHVTQEFVSRTLTTSGTLSTHMDQQFFQTGENBANK ID: XP_030326.1VERSION XP_030326.1 GI:147636261MDKFWWHAAW GLCLVPLSLA QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL61PTMAQMEKAL SIGPETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN121ASAPFEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS181GSSSERSSTS GGYIFYTFST VHPIPDEDSE WITDSTDRIP ATTLNSTSAT ATETATKRQE241TWDWPSWLPL PSESKNHLHT TTQMAGTSSN TISAGWEPNE ENEDERDRHL SFSGSGIDDD301EDFISSTIST TPRAFDHTKQ NQDWTQWNPS HSNPEVLLQT TTRMTDVDRN GTTAYEGNWN361PEAHPPLIHH EHHEEEETPH STSTIQATPS STTEETATQK EQWFGNRWHE GYRQTEKEDS421HSTTGTAAAS AHTSHPMQGR TTPSFEDSSW TDFFNPISHP MGRGHQAGRR MDMDSSHSIT481LQPTANPNTG LVEDLDRTGP LSMTTQQSNS QSFSTSHEGL EEDKDHPTTS TLTSSNRNDV541TGGRRDPNHS EGSTTLLEGY TSHYPHTKES RTFIPVTSAK TGSPGVTAVT VGDSNSNVNR601SLSGDQDTFH PSGGSHTTEG SESDGESHGS QEGGANTTSG PIRTEQIPEW LIILASLLAL661ALILAVCIAV NSRRRCGQKK KLVINSGNGA VEDRKPSGLN GEASKSQEMV HLVNKESSET721PDQFMTADET RNLQNVDMKI GVGENBANK ID: NP_000826.1VERSION NP_000826.1 GI:45041291MGGALGPALL LTSLPGAWAG LGPGQGEQGM TVAVVFSSSG PPQAQFRARL TPQSFLDLPL61EIQPLTVGVN TTNPSSLLTQ ICGLLGAAHV HGIVPEDNVD TEAVAQILDF ISSQTHVPIL121SISGGSAVVL TPKEPGSAFL QLGVSLEQQL QVLFKVLEEY DWSAFAVITS LHPGHALFLE181GVRAVADASH VSWRLLDVVT LELGEGGPRA RTQRLLRQLD APVPVAYCSR EEAEVLFAEA241AQAGLVGPGH VWLVPNLALG STDAPPATFP VGLISVVTES WRLSLRQKVR DGVAILALGA301HSYWRQHGTL PAPAGDCRVH PGPVSPAREA FYRHLLNVTW EGRDPSFSPG GYLVQPTMVV361IALNRHRLWE MVGRWEHGVL YMKYPVWPRY SASLQPVVDS RHLTVATLEE RPPVIVESPD421PGTGGCVPNT VPCRRQSNHT FSSGDVAPYT KLCCKGFCID ILKKLARVVK FSYDLYLVTN481GKHGKRVRGV WNGMIGEVYY KRADMAIGSL TINEERSEIV DPSVPFVETG ISVMVARSNG541TVSPSAFLEP YSPAVWVMMF VMCLTVVAIT VFMFEYPSPV SYNQNLTRGK KSGGPAFTIG601KSVWLLWALV FNNSVPIENP RGTTSKIMVL VWAFFAVIFL ASYTANLAAF MIQEQYIDTV661SGLSDKKPQR PQDQYPPFRF GIVPNGSTER NIRSNYRDMH THMVKFNQRS VEDALTSLKM721GKLDAFIYDA AVLNYMAGKD EGCKLVTIGS GKVPATTGYG IANQKDSHWK RAIDLALLQF781LGDGETQKLE TVWLSGICQN EKNEVMSSKL DIDNMAGVFY MLLVAMGLAL LVFAWEHLVY841WKLRHSVPNS SQLDPLLAFS RGIYSCPSGV QSLASPPRQA SPDLTASSAQ ASVLKNLQAA901RDMVTTAGVS SSLDRATRTI ENWGGGRRAP PPSPCPTPRS GPSPCLPTPD PPPEPSETGW961GPPDGGRAAL VRRAPQPPGR PPTPGPPLSD VSRVSRRPAW EARWPVRTGH CGRELSASER1021PLSPARCHYS SFPRADRSGR PFLPLFPEPP ELEDLPLLGP EQLARREALL HAAWARGSRP1081RHASLPSSVA EAFARPSSLP AGCTGPACAR PDGHSACRRL AQAQSMCLPI YREACQEGEQ1141AGAPAWQHRQ HVCLHAHAHL PFCWGAVCPH LPPCASHGSW LSGAWGPLGH RGRTLGLGTG1201YRDSGGLDEI SSVARGTQGF PGPCTWRRIS SLESEVGENBANK ID: CAA43045.1DEFINITION HUMAN CDW40 MRNA FOR NERVE GROWTH FACTOR RECEPTOR-RELATEDB-LYMPHOCYTE ACTIVATION MOLECULE.VERSION X60592.1 GI:29850CDS 48..881/CODON_START=11GCCTCGCTCG GGCGCCCAGT GGTCCTGCCG CCTGGTCTCA CCTCGCCATG GTTCGTCTGC61CTCTGCAGTG CGTCCTCTGG GGCTGCTTGC TGACCGCTGT CCATCCAGAA CCACCCACTG121CATGCAGAGA AAAACAGTAC CTAATAAACA GTCAGTGCTG TTCTTTGTGC CAGCCAGGAC181AGAAACTGGT GAGTGACTGC ACAGAGTTCA CTGAAACGGA ATGCCTTCCT TGCGGTGAAA241GCGAATTCCT AGACACCTGG AACAGAGAGA CACACTGCCA CCAGCACAAA TACTGCGACC301CCAACCTAGG GCTTCGGGTC CAGCAGAAGG GCACCTCAGA AACAGACACC ATCTGCACCT361GTGAAGAAGG CTGGCACTGT ACGAGTGAGG CCTGTGAGAG CTGTGTCCTG CACCGCTCAT421GCTCGCCCGG CTTTGGGGTC AAGCAGATTG CTACAGGGGT TTCTGATACC ATCTGCGAGC481CCTGCCCAGT CGGCTTCTTC TCCAATGTGT CATCTGCTTT CGAAAAATGT CACCCTTGGA541CAAGCTGTGA GACCAAAGAC CTGGTTGTGC AACAGGCAGG CACAAACAAG ACTGATGTTG601TCTGTGGTCC CCAGGATCGG CTGAGAGCCC TGGTGGTGAT CCCCATCATC TTCGGGATCC661TGTTTGCCAT CCTCTTGGTG CTGGTCTTTA TCAAAAAGGT GGCCAAGAAG CCAACCAATA721AGGCCCCCCA CCCCAAGCAG GAACCCCAGG AGATCAATTT TCCCGACGAT CTTCCTGGCT781CCAACACTGC TGCTCCAGTG CAGGAGACTT TACATGGATG CCAACCGGTC ACCCAGGAGG841ATGGCAAAGA GAGTCGCATC TCAGTGCAGG AGAGACAGTG AGGCTGCACC CACCCAGGAG901TGTGGCCACG TGGGCAAACA GGCAGTTGGC CAGAGAGCCT GGTGCTGCTG CTGCAGGGGT961GCAGGCAGAA GCGGGGAGCT ATGCCCAGTC AGTGCCAGCC CCTCGENBANK ID: AAB59544.1DEFINITION HUMAN NERVE GROWTH FACTOR RECEPTOR MRNA, COMPLETE CDS.VERSION M14764.1 GI:189204CDS 114..1397/CODON_START=11GCCGCGGCCA GCTCCGGCGG GCAGGGGGGG CGCTGGAGCG CAGCGCAGCG CAGCCCCATC61AGTCCGCAAA GCGGACCGAG CTGGAAGTCG AGCGCTGCCG CGGGAGGCGG GCGATGGGGG121CAGGTGCCAC CGGCCGCGCC ATGGACGGGC CGCGCCTGCT GCTGTTGCTG CTTCTGGGGG181TGTCCCTTGG AGGTGCCAAG GAGGCATGCC CCACAGGCCT GTACACACAC AGCGGTGAGT241GCTGCAAAGC CTGCAACCTG GGCGAGGGTG TGGCCCAGCC TTGTGGAGCC AACCAGACCG301TGTGTGAGCC CTGCCTGGAC AGCGTGACGT TCTCCGACGT GGTGAGCGCG ACCGAGCCGT361GCAAGCCGTG CACCGAGTGC GTGGGGCTCC AGAGCATGTC GGCGCCGTGC GTGGAGGCCG421ACGACGCCGT GTGCCGCTGC GCCTACGGCT ACTACCAGGA TGAGACGACT GGGCGCTGCG481AGGCGTGCCG CGTGTGCGAG GCGGGCTCGG GCCTCGTGTT CTCCTGCCAG GACAAGCAGA541ACACCGTGTG CGAGGAGTGC CCCGACGGCA CGTATTCCGA CGAGGCCAAC CACGTGGACC601CGTGCCTGCC CTGCACCGTG TGCGAGGACA CCGAGCGCCA GCTCCGCGAG TGCACACGCT661GGGCCGACGC CGAGTGCGAG GAGATCCCTG GCCGTTGGAT TACACGGTCC ACACCCCCAG721AGGGCTCGGA CAGCACAGCC CCCAGCACCC AGGAGCCTGA GGCACCTCCA GAACAAGACC781TCATAGCCAG CACGGTGGCA GGTGTGGTGA CCACAGTGAT GGGCAGCTCC CAGCCCGTGG841TGACCCGAGG CACCACCGAC AACCTCATCC CTGTCTATTG CTCCATCCTG GCTGCTGTGG901TTGTGGGCCT TGTGGCCTAC ATAGCCTTCA AGAGGTGGAA CAGCTGCAAG CAGAACAAGC961AAGGAGCCAA CAGCCGGCCA GTGAACCAGA CGCCCCCACC AGAGGGAGAA AAACTCCACA1021GCGACAGTGG CATCTCCGTG GACAGCCAGA GCCTGCATGA CCAGCAGCCC CACACGCAGA1081CAGCCTCGGG CCAGGCCCTC AAGGGTGACG GAGGCCTCTA CAGCAGCCTG CCCCCAGCCA1141AGCGGGAGGA GGTGGAGAAG CTTCTCAACG GCTCTGCGGG GGACACCTGG CGGCACCTGG1201CGGGCGAGCT GGGCTACCAG CCCGAGCACA TAGACTCCTT TACCCATGAG GCCTGCCCCG1261TTCGCGCCCT GCTTGCAAGC TGGGCCACCC AGGACAGCGC CACACTGGAC GCCCTCCTGG1321CCGCCCTGCG CCGCATCCAG CGAGCCGACC TCGTGGAGAG TCTGTGCAGT GAGTCCACTG1381CCACATCCCC GGTGTGAGCC CAACCGGGGA GCCCCCGCCC CGCCCCACAT TCCGACAACC1441GATGCTCCAG CCAACCCCTG TGGAGCCCGC ACCCCCACCC TTTGGGGGGG GCCCGCCTGG1501CAGAACTGAG CTCCTCTGGG CAGGACCTCA GAGTCCAGGC CCCAAAACCA CAGCCCTGTC1561AGTGCAGCCC GTGTGGCCCC TTCACTTCTG ACCACACTTC CTGTCCAGAG AGAGAAGTGC1621CCCTGCTGCC TCCCCAACCC TGCCCCTGCC CCGTCACCAT CTCAGGCCAC CTGCCCCCTT1681CTCCCACACT GCTAGGTGGG CCAGCCCCTC CCACCACAGC AGGTGTCATA TATGGCGGGC1741CAACACCAGC GATGGTACTA GGGGCAAGTG ACAAGGCCCC AGAGACTGAG AGGGAGGAAT1801CGAGGAACCA GAGCCATGGA CTCTACACTG TGAACTTGGG GAACAAGGGT GGCATCCCAG1861TGGCCTCAAC CCTCCCTCAG CCCCTCTTGC CCCCCACCCC AGCCTAAGAT GAAGAGGATC1921GGAGGCTTGT CAGAGCTGGG AGGGGTTTTC GAAGCTCAGC CCACCCCCCT CATTTTGGAT1981ATAGGACAGT GAGGCCCAGG GAGAGGGCAT GATTCGCCCA AAGCCAGACA GCAACGGGGA2041GGCCAAGTGC AGGCTGGCAC CGCCTTCTCT AAATGAGGGG CCTCAGGTTT GCCTGAGGGC2101GAGGGGAGGG TGGCAGGTGA CCTTCTGGGA AATGGCTTGA AGCCAAGTCA GCTTTGCCTT2181CCACGCTGTC TCCAGACCCC CACCCCTTCC CCACTGCCTG CCCACCCGTG GAGATGGGAT2221GCTTGCCTAG GGCCTGGTCC ATGATGGAGT CAGGTTTGGG GTTCGTGGAA AGGGTGCTGC2281TTCCCTCTGC CTGTCCCTCT CAGGCATGCC TCTGTGACAT CAGTGGCATG GCTCCAGTCT2341GCTGCCCTCC ATCCCGACAT GGACCCGGAG CTAACACTGG CCCCTAGAAT CAGCCTAGGG2401GTCAGGGACC AAGGACCCCT CACCTTGCAA CACACAGACA CACGCACACA CACACACAGG2461AGGAGAAATC TCACTTTTCT CCATGAGTTT TTTCTCTTGG GCTGAGACTG GATACTGCCC2521GGGGCAGCTG CCAGAGAAGC ATCGGAGGGA ATTGAGGTCT GCTCGGCCGT CTTCACTCGC2581CCCCGGGTTT GGCGGGCCAA GGACTGCCGA CCGAGGCTGG AGCTGGCGTC TGTCTTCAAG2841GGCTTACACG TGGAGGAATG CTCCCCCATC CTCCCCTTCC CTGCAAACAT GGGGTTGGCT2701GGGCCCAGAA GGTTGCGATG AAGAAAAGCG GGCCAGTGTG GGAATGCGGC AAGAAGGAAT2761TGACTTCGAC TGTGACCTGT GGGGATTTCT CCCAGCTCTA GACAACCCTG CAAAGGACTG2821TTTTTTCCTG AGCTTGGCCA GAAGGGGGCC ATGAGGCCTC AGTGGACTTT CCACCCCCTC2881CCTGGCCTGT TCTGTTTTGC CTGAAGTTGG AGTGAGTGTG GCTCCCCTCT ATTTAGCATG2841ACAAGCCCCA GGCAGGCTGT GCGCTGACAA CCACCGCTCC CCAGCCCAGG GTTCCCCCAG3001CCCTGTGGAA GGGACTAGGA GCACTGTAGT AAATGGCAAT TCTTTGACCT CAACCTGTGA3061TGAGGGGAGG AAACTCACCT GCTGGCCCCT CACCTGGGCA CCTGGGGAGT GGGACAGAGT3121CTGGGTGTAT TTATTTTCCT CCCCAGCAGG TGGGGAGGGG GTTTGGTGGC TTGCAAGTAT3181GTTTTAGCAT GTGTTTGGTT CTGGGGCCCC TTTTTACTCC CCTTGAGCTG AGATGGAACC3241CTTTTGGCCC CCAGCTGGGG GCCATGAGCT CCAGACCCCC AGCAACCCTC CTATCACCTC3301CCCTCCTTGC CTCCTGTGTA ATCATTTCTT GGGCCCTCCT GAAACTTACA CACAAAACGT3361TAAGTGATGA ACATTAAATA GCAAAGGENEANK ID: NP_002502.1VERSION NM_002511.1 GI:4505406CDS 140..1312/CODON_START=11GTGCTGTGAG GCTTGCCCGC GGACAGTAAA CTTGCAGGGG CGAGAGGGAG GGACATCGAT61TAAACCTAAA TCGTGGGCGT TCAGTCCTCA GGGCACCGAG CGCGTGAAAA CTCCAGCGGA121CTCTGCTGGA AAGGAGATCA TGCCCTCTAA GTCTCTTTCC AACCTCTCGG TGACCACCGG181CGCGAATGAG AGCGGTTCCG TTCCCGAGGG GTGGGAAAGG GATTTCCTGC CGGCCTCGGA241CGGGACCACC ACGGAGTTGG TGATCCGCTG TGTGATCCCG TCCCTCTACC TGCTCATCAT301CACCGTGGGC TTGCTGGGCA ACATCATGCT GGTGAAGATC TTCATCACCA ACAGCGCCAT361GAGGAGCGTC CCCAACATCT TCATCTCTAA CCTGGCGGCC GGGGACTTGC TGCTGCTGCT421CACCTGCGTC CCGGTGGACG CCTCGCGCTA CTTCTTCGAC GAGTGGATGT TTGGCAAGGT481GGGCTGCAAA CTGATCCCTG TCATCCAGCT CACTTCCGTG GGGGTTTCCG TGTTCACTCT541CACTGCCCTC AGCGCCGACA GGTACAGAGC CATCGTTAAC CCCATCGACA TGCAGACGTC601AGGGCCATTG CTGCGGACCT GTGTGAAGGC CATGGGTATC TGGGTGGTCT CCGTGTTGCT661GGCAGTTCCC GAAGCGGTGT TTTCAGAAGT GGCTCGCATC AGTAGCTTGG ATAATAGCAG721CTTCACAGCA TGTATCCCAT ACCCTCAAAC AGATGAATTA CATCCAAAGA TTCATTCAGT781GCTCATTTTC TTGGTCTATT TCCTCATACC ACTTGCTATT ATTAGCATTT ATTATTATCA841TATTGCAAAG ACCTTAATTA AAAGCGCACA CAATCTTCCT GGAGAATACA ATGAACATAC901CAAAAAACAG ATGGAAACAC GGAAACGCCT GGCTAAAATT GTGCTTGTCT TTCTGGGCTG981TTTCATCTTC TGTTGGTTTC CAAACCACAT CCTTTACATG TATCGGTCTT TCAACTATAA1021TGAGATTGAT CCATCTCTAG GCCACATGAT TGTCACCTTA GTTGCCCGGG TTCTCAGTTT1081TGGCAATTCT TGTGTCAACC CATTTGCTCT TTACCTACTC AGTGAAAGCT TCAGGAGGCA1141TTTCAACAGC CAACTCTGCT GTGGGAGGAA GTCCTATCAA GAGAGAGGAA CCAGCTACCT1201ACTCAGCTCT TCAGCGGTGC GTATGACATC TCTGAAAAGC AATGCTAAGA ACATGGTGAC1261CAATTCTGTT TTACTAAATG GGCACAGCAT GAAGCAGGAA ATGGCAATCT GATTTTGGCC1321ATTCAACTCA CTACCTGGAG AGAACTTAGT AAGENBANK ID: Q00941ESTDNA TYPE: CDNACGAAGGCGCGGCGGGCTCGGGGGCGGAGAACCTGACCTGCGAGATCCGAGCCGAGCGCTTTCTTTTCTGCGCGTGGCGGGAGGGGCCAGCGGCGCCCGCGGACGTCCGGTACTCGCTGCGAGTCCTTAACTCCACGGGTCACGACGTGGCGCGATGCATGGCCGACCCTGGGGATGACGTCATGACACAGTGCATTGCGAACGACTTGTCACTGATGGGGAGTGAGGCCTACTTGGTCGTGACCGGTCGCACCGGAGCGGGGCCAGTGCGGATCCTGGACGACTTGGTGGCTACGAAGGCGCTCGACCGACTCGATCCCTCACCTGACGTCACCGAGTCCTGTAACTATTCCCACTGCACCGAGTCGTGGGCGCCGCCCTAGACCTGTGCATCCTATGAGGTGCGGGACTTGCAGTGTGAGGTCCAGTGGCAGAGCACATATCCAGGAAGCTCACTCCAGAATGTGCTCATCCGCGAGGAGAGGCGGTTTGCCTTTCGCACGCTGTTCCGCTCGAGGTTACATTGCTAAAGTGCGCACAGGGTACACGAGGATGAGCACTGTGGCGAATGGTATAAGCGGCATCCTGTTATGGCTGAGGENBANK ID: P05106ESTDNA TYPE: CDNACGGCCGCTGCACAGCAGCCCATTGCTGGACATGCAGGTGTCAGTACGCGTGGTACAGTTGCAGTAGTAGCCGGTCCAGTCGGAGTCACACAGGCAGTCCCCACAGCTGCACTGGCCATGGCCTGAGCACATCTCCCCCTTGTAGCGGACACAGGAGAAGTCGTCACACTCGCAGTACTTGCCCGTGATCTTGCCAAAGTCACTGCTGTGGCAGACACATTGACCACAGAGGCACTCGCCCCGCTGGCTGCAGACGGGCTGACCCTCTCGGGGGCTGCACTCGTCCTGCTGGGAAGGGCGATAGTCCTCCTCTGAGCACTCACACTGGGATCCCAGCCAGCCAGGCCCACAACGGCATACCCCACACTCAAAGGTCCCATTGCCATTGTTGCAGCGATGGCTATTAGGTTCAGCTTGGGCCTGGCAGGCACAGTCACAATCAAAGGTGACCTGGACGATCAGGCTGTCCTTGAAGCCCACGGGCTTTATGGTAAAGGACTTCTCCTTCTCCTGGGGACAGCCTCGCACCTTGGCCTCAATGCTGAAGCTCACCGTGTCTCCAATCTTGAGTCCCATACAAGACTTGAGGCCAGGGATGACCTCATTGGTGAGGCAGGTEST GENBANK ACC: BF115658DNA TYPE: CDNAGCGGCCGCTGCACAGCAGCCCATTGCTGGACATGCAGGTGTCAGTACGCGTGGTACAGTTGCAGTAGTAGCCGGTCCAGTCGGAGTCACACAGGCAGTCCCCACAGCTGCACTGGCCATGGCCTGAGCACATCTCCCCCTTGTAGCGGACACAGGAGAAGTCGTCACACTCGCAGTACTTGCCCGTGATCTTGCCAAAGTCACTGCTGTGGCAGACACATTGACCACAGAGGCACTCGCCCCGCTGGCTGCAGACGGGCTGACCCTCCCGGGGGCTGCATTCGTCCTGCTGGGAAGGGCGATAGTCCTCCTCTGAGCACTCACACTGGGATCCCAGCCAGCCAGGCCCACAACGGCATACCCCACACTCAAAGGTCCCATTGCCATTGTTGCAGCGATGGCTATTAGGTTCAGCTTGGGCCTGGCAGGCACAGTCACAATCAAAGGTGACCTGNACGATCAGGCTGTCCTTGAAGCCCACGGGCTNTATGGTAAAGGACTTCTCCTTCTCCTGGGGACAGCCTCGCACCTTGGCCTCAATGCTGAAGCTCACCGTGTCTCCAATCTTGAGTCCCATACAAGACTTGAGGCCAGGGATGACCTCATTGTTGAGGCATGTGGCATTGAAGGATAGAGANCACTCTTCAGGACGTCACGCACTTTCAGCTCGACTTTAGAACGGAATTTCCATAAGCATCAACAATGAGCCTGAGGACATTGCCTGAATCCATGGACAGAACCCCCACTGTGGTCCCESTGENBANK ACC: BFD62996CGGCCGCTGCACAGCAGCCCATTGCTGGACATGCAGGTGTCAGTACGCGTGGTACAGTTGCAGTAGTAGCCGGTCCAGTCGGAGTCACACAGGCAGTCCCCACAGCTGCACTGGCCATGGCCTGAGCACATCTCCCCCTTGTAGCGGACACAGGAGAAGTCGTCACACTCGCAGTACTTGCCCGTGATCTTGCCAAAGTCACTGCTGTGGCAGACACATTGACCACAGAGGCACTCGCCCCGCTGGCTGCAGACGGGCTGACCCTCCCGGGGGCTGCATTCGTCCTGCTGGGAAGGGCGATAGTCCTCCTCTGAGCACTCACACTGGGATCCCAGCCAGCCAGGCCCACAACGGCATACCCCACACTCAAAGGTCCCATTGCCATTGTTGCAGCGATGGCTATTATGTTCAGCTTGGGCCTGGCAGGCACAGTCACAATCAAAGGTGACCTGGACGATCAGGCTGTCCTTGAAGCCCACGGGCTTTATGGTAAAGGAATTCTCCTTTTCCTTGGGACAGACTCGCACCTTGGCCCTAATGCTGAAGCTCACCGAGATCTTCATGENBANK ID: CAA52348.1VERSION X74295.1 GI:437781CDS <1..234/CODON_START=11AAGATGGGAT TCTTCAAACG GGCGAAGCAC CCCGAGGCCA CCGTGCCCCA GTACCATGCG61GTGAAGATTC CTCGGGAAGA CCGACAGCAG TTCAAGGAGG AGAAGACGGG CACCATCCTG121AGGAACAACT GGGGCAGCCC CCCGCCGGAC GGCCCGGATG CACACGCCAT CCTCGCTGCT181GACGGGCATC CCCAGCTGGG CCCCAATGGG CATCCAGGGC CAGGCACCGC CTAGGTTCCC241ATGTCCCAGC CTGCGCTGTG GCTGCCCTCC ATCCCTTCCC CAGAGATGGC TCCTTGGGAT301GAAGAGGGTA GAGTCGGCTG CTGGTGTCAC ATCAAGAATT TGGCAGGATC GGCTTCCTCA361GGGGCACAGA CCTCTCCCAC CCACAAGAAC TGCTGCCACG CAACTTCCCC TTAGAGTGCT421GTGAGATGAG AGTGGGTAAA TCAGGGACAG GGCCATGGGG TAGGGTGAGA AGGGCAGGGG481TGTCCTGATG CAAAGGTGGG GAGAAGGATC CTAATCCCTT CCTCTCCCAT TCACCCTGTG541TAACAGGACC CCAAGGACCT GCCTCCCCGG AAGTGCCTTA ACCTAGAGGG TCGGGGAGGA601GGTTGTGTCA CTGACTCAAG GCTGCTCCTT CTCTAGTTTC CCCTCTCATC TGACCTTAGT661TTGCTGCCAT CAGTCTAGTG GTTTCGTGGT TTCGTCTATT TATTAAAAAA TCGGAACCCGENBANK ID: M57627VERSION CAA51942.1 GI:5801771MHSSALGENBANK ID: AAA52578.1VERSION AAA52578.1 GI:1833641MWLQSLLLLG TVACSISAPA RSPSPSTQPW EHVNAIQEAR RLLNLSRDTA AEMNETVEVI61SEMFDLQEPT CLQTRLELYK QGLRGSLTKL KGPLTMMASH YKQRCPPTPE TSCATQIITF121ESFKENLKDF LLVIPFDCWE PVQEGENBANK ID: AAA58482.1VERSION AAA58482.1 GI:1826691METNFSIPLN ETEEVLPEPA GHTVLWIFSL LVHGVTFVFG VLGNGLVIMV AGFRMTRTVN61TICYLNLALA DFSFSAILPF RNVSVANREK WPFASFLCKL VHVNIDINLF VSVYLITIIA121LDRCICVLHP AWAQNHRTMS LAKRVMTGLW IFTIVLTLPN FIFNTTISTT NGDTYCIFNF181AFWGDTAVER LNVFITNAKV FLILHFIIGF TVPMSIITVC YGIIAAKIHR NHMIKSSRPL241RVFAAVVASF FICWFPYELI GILMAVWLKE NLLNGKYKII LVLINPTSSL AFFNSCLNPI301LYVFMGRNFQ ERLIRSLPTS LERALTEVPD SAQTSNTHTT SASPPEETEL QAMGENBANK ID: P17774VERSION P17774 GI:1213241MSESLVVCDV AEDLVEKLRK FRFRKETNNA ATINKIDMDK RLVVLDEELE GISPDELKDE61LPERQPRFIV YSYKYQHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNK LVQTAELTKV121FEIRNTEDLT EEWLREKLGF FHGENBANK ID: P51858VERSION P51858 GI:17081571MSRSNRQKEY KCGDLVFAKM KGYPHWPARI DEMPEAAVKS TANKYQVFFF GTHETAFLGP61KDLFPYEESK EKFGKPNKRK GFSEGLWEIE NNPTVKASGY QSSQKKSCVE EPEPEPEAAE121GDGDKKGNAE GSSDEEGKLV IDEPAKEKNE KGALKRRAGD LLEDSPKRPK EAENPEGEEK181EAATLEVERP LPNEVEKNST PSEPGSGRGP PQEEEEEEDE EEEATKEDAE APGIRDHESL241GENBANK ID: P10147VERSION P10147 GI:1270781MQVSTAALAV LLCTMALCNQ FSASLAADTP TACCFSYTSR QIPQNFIADY FETSSQCSKP61GVIFLTKRSR QVCADPSEEW VQKYVSDLEL SAGENBANK ID: P13500VERSION P13500 GI:1268421MKVSAALLCL LLIAATFIPQ GLAQPDAINA PVTCCYNFTN RKISVQRLAS YRRITSSKCP61KEAVIFKTIV AKEICADPKQ KNVQDSMDHL DKQTQTPKTGENBANK ID: NP_065391.1VERSION NP_065391.1 GI:100926211MGVLLTQRTL LSLVLALLFP SMASMAAIGS CSKEYRVLLG QLQKQTDLMQ DTSRLLQPYI61RIQGLDVFKL REHCRERPGA FPSEETLRGL GRRGFLQTLN ATLGCVLHRL ADLEQRLFKA121QDLERSGLNI EDLEKLQMAR FNILGLRNNI YCMAQLLDNS DTAEPTKAGR DASQPPTPTP181ASDAFQRKLE GCRFLHGYHR FMESVGRVFS KWGESFNRSR RHSPHQALRK GVRRTRPSRK241GKRLMTRGQL PRGENBANK ID: XP_013053.3VERSION XP_013053.3 GI:147682771MERERETLQA WEERVGQELD RVVAFWNEHS HDQEEGGFFT CLGREGRVYD DLKYVWLQGR61QVWMYCRLYR TFERFRHAQL LDAAKAGGEF LLRYARVAPP GKKCAFVLTR DGRPVKVQRT121IFSECFYTMA MNELWRATGE VRYQTEAVEM MDQIVHWVQE DASGLGRPQL QGAPAAEPMA181VPMNLLNLVE QLGEADEELA GKYAELGDWC ARRILQHVQR DGQAVLENVS EGGKELPGCL241GRQQNPGHTL EAGWFLLRHC IRIGDPELRA HVIDKWLLLP FHSGWDPDHG GLFYFQDADN301FCPTQLEWAN KLWWPHSEAM IAFLMGYSDS GDPVLLRLFY QVAEYTFRQF RDPEYGENFG361YLSREGKVAL SIKGGPFKGC FHVPRCLAMC EEMLGALLSR PAPAPSPAPT PACRGAEGENBANK ID: B31848VERSION B31848 GI:870051MTCKNSQLER NIETIINTFH QYSVKLGEPD TLNQGEFKEL VRKDLQNFLK KENKNEKVIE61HIMEDLDTNA DKQLSFEEFI MLMARLTWAS HENNEEGDEG PGHHHKPGLG ECTPGENBANK ID: CAA38698.1VERSION CAA38698.1 GI:355221MPVNRLFPCF LQLLAGLALP AVFFQQWALS AGNGSSEVEV VFFQEVWGRS YCRALERLVD61VVSEYPSEVE HMFSFSCVSL LRCTGCCGDE NLHCVPVETA NVTMQLLKIR SGDRPSYVEL121TFSQHVRCEC RPLREKMKPE RCGDAVPRRGENBANK ID: AAA35789.1VERSION AAA35789.1 GI:1819711MNFLLSWVHW SLALLLYLHH AKWSQAAPNA EGGGQNHHEV VKFMDVYQRS YCHFIETLVD61IFQEYPDEIE YIFKPSCVFL NRCGGCCNDE GLECVPTEES NITMQINRIK PHQGQHIGEM121SFLQHNKCEC RPKKDRARQE NPCGPCSERR KHLFVQDPQT CKCSCKNTDS RCKARQLELN181ERTCRCDKPR RGENBANK ID: AAA66062.1VERSION AAA66062.1 GI:5368981MWKRWLALAL ALVAVAWVRA EEELRSKSKI CANVFCGAGR ECAVTEKGEF TCLCIEQCKP61HKRFVCGSNG KTYLNHCELH RDACLTGSKI QVDYDGHCKE KKSVSPSASP VVCYQSNRDE121LRRRIIQWLE AEIIFDGWFS KGSNYSEILD KYFKNFDNGD SRLDSSEFLK FVEQNETAIN181ITTYPDQENN KLLRGLCVDA LIELSDENAD WKLSFQEFLK CLNPSFNPPE KKCALEDETY241ADGAETEVDC NRCVCACGNW VCTANTCDGK NQKGAQTQTE EEMTRYVQEL QKHQETAEKT301KRVSTKEIGENBANK ID: AAA59872.1VERSION AAA59872.1 GI:3980381MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWDEDV ADAEECAGRC61GPLMDCRAFH YNVSSHGCQL LFWTQRSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG121TMATTVGGLP CQAWSHKFPN DHKYTFTLRN GLEENFCRNP DGDPGGFWCY TTDPAVRFQS181CGIKSCREAA CVWCNGEEYR GAVDRTESGR ECQRWQLQHP HQHPFEPGKF LDQGLDDNYC241RNPDGSERPW CYTTDPQIER EFCDLFRCGS EAQFRQEATT VSCFRGKGEG YRGTANTTTA301GVPCQRWDAQ IFHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR361CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR421NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFENCGK RVDRLDQRRS481KLRVVGGHPG NSFWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT541LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVFFGT601KCEIAGWGET KGTGNDTVLN VAFLNVTSNQ ECNIKHRGRV RESENCTEGL LADVGACEGD661YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL GGENBANK ID: P01579VERSION P01579 GI:1244791MKYTSYILAF QLCIVLGSLG CYCQDPYVKE AENLKKYFNA GHSDVADNGT LFLGILKNWK61EESDRKIMQS QIVSFYFKLF KNFKDDQSIQ KSVETIKEDM NVKFFNSNKK KRDDFEKLTN121YSVTDLNVQR KAIHELIQVM AELSPAAKTC KRKRSQMLFR GRRASQGENBANK ID: XP_035842.1DEFINITION HOMO SAPIENS SMALL INDUCIBLE CYTOKINE A5 (RANTES) (SCYAS),MRNA.CDS 22..297/CODON_START=11ACAGCCTCTC CCACAGGTAC CATGAAGGTC TCCGCGGCAG CCCTCGCTGT CATCCTCATT61GCTACTGCCC TCTGCGCTCC TGCATCTGCC TCCCCATATT CCTCGGACAC CACACCCTGC121TGCTTTGCCT ACATTGCCCG CCCACTCCCC CGTGCCCACA TCAAGGAGTA TTTCTACACC181AGTGGCAAGT GCTCCAACCC AGCAGTCGTC TTTGTCACCC GAAAGAACCG CCAAGTGTGT241GCCAACCCAG AGAAGAAATG GGTTCGGGAG TACATCAACT CTTTGGAGAT GAGCTAGGAT301GGAGAGTCCT TGAACCTGAA CTTACACAAA TTTGCCTGTT TCTGCTTGCT CTTCTCCTAG361CTTGGGAGGC TTCCCCTCAC TATCCTACCC CACCCGCTCC TTGAAGGGCC CAGATTCTAC421CACACAGCAG CAGTTACAAA AACCTTCCCC AGCCTGGACC TGGTGGCTCA CGCCTGTAAT481CCCAGCACTT TGGGAGGGCA AGGTGGGTGG ATCACTTGAG GTCAGGAGTT CGAGACCAGC541CTGGCCAACA TGATGAAACC CCATCTCTAC TAAAAATACA AAAAATTAGC CGGGCGTGGT601AGCGGGCGCC TGTAGTCCCA GCTACTCGGG AGGCTGAGGC AGGAGAATGG CGTGAACCCG661GGAGGCGGAG CTTGCAGTGA GCCGAGATCG CGCCACTGCA CTCCAGCCTG GGCGACAGAG721CGAGACTCCG TCTCAAAAAA AAAAAAAAAA AAAAAAATAC AAAAATTAGC CGGGCGTGGT781GGCCCACGCC TGTAATCCCA GCTACTCGGG AGGCTAAGGC AGGAAAATTG TTTGAACCCA841GGAGGTGGAG GCTGCAGTGA GCTGAGATTG TGCCACTTCA CTCCAGCCTG GGTGACAAAG901TGAGACTCCG TCACAACAAC AACAACAAAA AGCTTCCCCA ACTAAAGCCT AGAAGAGCTT961CTGAGGCGCT GCTTTGTCAA AAGGAAGTCT CTAGGTTCTG AGCTCTGGCT TTGCCTTGGC1021TTTGCCAGGG CTCTGTGACC AGGAAGGAAG TCAGCATGCC TGTAGAGGCA AGGAGGGGAG1081GAACACTGCA CTCTTAAGCT TCCGCCGTCT CAACCCCTCA CAGGAGCTTA CTGGCAAACA1141TGAAAAATCG GGENBANK ID: CAA72079.1DEFINITION H. SAPIENS MRNA FOR ESTROGEN SULFOTRANSFERASE.CDS 63..947/CODON_START=11GCCTTGAAGA GATATAAACT AGATCAATTT CTTTCACAGG ATCAACTAAA CAGTGTACCA61CAATGAATTC TGAACTTGAC TATTATGAAA AGTTTGAAGA AGTCCATGGG ATTCTAATGT121ATAAAGATTT TGTCAAATAT TGGGATAATG TGGAAGCGTT CCAGGCAAGA CCAGATGATC181TTGTCATTGC CACCTACCCT AAATCTGGTA CAACCTGGGT TAGTGAAATT GTGTATATGA241TCTATAAAGA GGGTGATGTG GAAAAGTGCA AAGAAGATGT AATTTTTAAT CGAATACCTT301TCCTGGAATG CAGAAAAGAA AACCTCATGA ATGGAGTAAA ACAATTAGAT GAGATGAATT361CTCCTAGAAT TGTGAAGACT CATTTGCCAC CTGAACTTCT TCCTGCCTCA TTTTGGGAAA421AGGATTGTAA GATAATCTAT CTTTGCCGGA ATGCAAAGGA TGTGGCTGTT TCCTTTTATT481ATTTCTTTCT AATGGTGGCT GGTCATCCAA ATCCTGGATC CTTTCCAGAG TTTGTGGAGA541AATTCATGCA AGGACAGGTT CCTTATGGTT CCTGGTATAA ACATGTAAAA TCTTGGTGGG601AAAAGGGAAA GAGTCCACGT GTACTATTTC TTTTCTACGA AGACCTGAAA GAGGATATCA661GAAAAGAGGT GATAAAATTG ATACATTTCC TGGAAAGGAA GCCATCAGAG GAGCTTGTGG721ACAGGATTAT ACATCATACT TCGTTCCAAG AGATGAAGAA CAATCCATCC ACAAATTACA781CAACACTGCC AGACGAAATT ATGAACCAGA AATTGTCGCC CTTCATGAGA AAGGGAATTA841CAGGAGACTG GAAAAATCAC TTTACAGTAG CCCTGAATGA AAAATTTGAT AAACATTATG901AGCAGCAAAT GAAGGAATCT ACACTGAAGT TTCGAACTGA GATCTAAGAA GGTCTTGENBANK ID: AAA63210.1DEFINITION HUMAN KERATINOCYTE GROWTH FACTOR MRNA, COMPLETE CDS.CDS 446..1030/CODON_START=11ACGCGCTCAC ACACAGAGAG AAAATCCTTC TGCCTGTTGA TTTATGGAAA CAATTATGAT61TCTGCTGGAG AACTTTTCAG CTGAGAAATA GTTTGTAGCT ACAGTAGAAA GGCTCAAGTT121GCACCAGGCA GACAACAGAC ATGGAATTCT TATATATCCA GCTGTTAGCA ACAAAACAAA181AGTCAAATAG CAAACAGCGT CACAGCAACT GAACTTACTA CGAACTGTTT TTATGAGGAT241TTATCAACAG AGTTATTTAA GGAGGAATCC TGTGTTGTTA TCAGGAACTA AAAGGATAAG301GCTAACAATT TGGAAAGAGC AAGTACTCTT TCTTAAATCA ATCTACAATT CACAGATAGG361AAGAGGTCAA TGACCTAGGA GTAACAATCA ACTCAAGATT CATTTTCATT ATGTTATTCA421TGAACACCCG GAGCACTACA CTATAATGCA CAAATGGATA CTGACATGGA TCCTGCCAAC481TTTCCTCTAC AGATCATGCT TTCACATTAT CTGTCTAGTG GGTACTATAT CTTTAGCTTG541CAATGACATG ACTCCAGAGC AAATGGCTAC AAATGTGAAC TGTTCCAGCC CTGAGCGACA601CACAAGAAGT TATGATTACA TGGAAGGAGG GGATATAAGA GTGAGAAGAC TCTTCTGTCG661AACACAGTGG TACCTGAGGA TCGATAAAAG AGGCAAAGTA AAAGGGACCC AAGACATGAA721GAATAATTAC AATATCATGG AAATCAGGAC AGTGGCAGTT GGAATTGTGG CAATCAAAGG781GGTGGAAAGT GAATTCTATC TTGCAATGAA CAAGGAAGGA AAACTCTATG CAAAGAAAGA841ATGCAATGAA GATTGTAACT TCAAAGAACT AATTCTGGAA AACCATTACA ACACATATGC901ATCAGCTAAA TGGACACACA ACGGAGGGCA AATGTTTCTT GCCTTAAATC AAAAGCCCAT961TCCTGTAAGA GGAAAAAAAA CGAAGAAAGA ACAAAAAACA GCCCACTTTC TTCCTATGGC1021AATAACTTAA TTGCATATGG TATATAAAGA ACCCAGTTCC AGCAGGGAGA TTTCTTTAAG1081TGGACTGTTT TCTTTCTTCT CAAAATTTTC TTTCCATTTA TTTTTTAGTA ATCAAGAAAG1141GCTGGAAAAA CTACTGAAAA ACTGATCAAG CTGGACTTGT GCATTTATGT TTGTTTTAAG1201ACACTGCATT AAAGAAAGAT TTGAAAAGTA TACACAAAAA TCAGATTTAG TAACTAAAGG1261TTGTAAAAAA TTGTAAAACT GGTTGTACAA TCATGATGTT AGTAACACTA ATTTTTTTCT1321TAAATTAATT TACCCTTAAG AGTATGTTAG ATTTGATTAT CTGATAATGA TTATTTAAAT1381ATTCCTATCT GCTTATAAAA TGGCTGCTAT AATAATAATA ATACAGATGT TGTTATATAA1441CCTATATCAG ACCTACAGGC TTCTGGCAGG ATTTGTCAGA TAATCAACCC ACACTAACTA1501TCGAAAATGA GCAGCATTTT AAATGCTTTC TAGTGAAAAA TTATAATCTA CTTAAACTCT1561AATCAGAAAA AAAATTCTCA AAAAAACTAT TATGAAAGTC AATAAAATAG ATAATTTAAC1621AAAAGTACAG GATTAGAACA TGCTTATACC TATAAATAAG AACAAAATTT CTAATCCTGC1681TCAAGTGGAA AGGGTATTGC TAAAAGGATG TTTCCAAAAA TCTTGTATAT AAGATAGCAA1741CAGTGATTGA TGATAATACT GTACTTCATC TTACTTGCCA CAAAATAACA TTTTATAAAT1801CCTCAAAGTA AAATTGAGAA ATCTTTAACT TTTTTTCAAC TAACATAATC TATCTTTGTA1861TAATTCATAT TTGGGAATAT GGCTTTTAAT AATGTTCTTC CCACAAATAA TCATGCTTTT1921TTCCTATGGT TACAGCATTA AACTCTATTT TAAGTTGTTT TTGAACTTTA TTGTTTTGTT1981ATTTAAGTTT ATGTTATTTA TAAAAAAAAA ACCTTAATAA GCTGTATCTG TTTCATATGC2041TTTTAATTTT AAAGGAATAA CAAAACTGTC TGGCTCAACG GCAAGTTTCC CTCCCTTTTC2101TGACTGACAC TAAGTCTACC ACACAGCACT TGGGCCAGCA AATCCTCGAA GCAGACAAAA2161ATAAGAGCCT GAAGCAATGC TTACAATAGA TGTCTCACAC AGAACAATAC AAATATGTAA2221AAACTCTTTC ACCACATATT CTTGCCAATT AATTGGATCA TATAAGTAAA ATCATTACAA2281ATATAAGTAT TTACAGGATT TTAAAGTTAG AATATATTTG AATGCATGGG TAGAAAATAT2341CATATTTTAA AACTATGTAT ATTTAAATTT AGTAATTTTC TAATCTCTAG AAATCTCTGC2401TGTTCAAAAG GTGGCAGCAC TGAAAGTTGT TTTCCTGTTA GATGCCAAGA GCACAATGCC2461CAAAATAGAA GATGCAGTTA AGAATAAGGG GCCCTGAATG TCATGAAGGC TTGAGGTCAG2521CCTACAGATA ACAGGATTAT TACAAGGATG AATTTCCACT TCAAAAGTCT TTCATTGGCA2581GATCTTGGTA GCACTTTATA TGTTCACCAA TGGGAGGTCA ATATTTATCT AATTTAAAAG2641GTATGCTAAC CACTGTGCTT TTAATTTCAA AATATTTGTC ATTCAAGTCC CTTTACATAA2701ATAGTATTTC GTAATACATT TATAGATGAG ACTTATATGA AAAGGCTAGG TCAACAAAAA2761CAATAGATTC ATTTAATTTT CCTGTGGTTA ACCTATACGA CCAGGATGTA GAAAACTAGA2821AAGAACTGCC CTTCCTCACA TATACTCTTG CGAGAGAGCA TGAATGCTAT TCTGAACTAT2881CACCTGATTC AAGGACTTTG CTAGCTAGGT TTTGAGGTCA GGCTTCAGTA ACTGTAGTCT2941TGTGAGCATA TTGAGGGCAG AGGAGGACTT AGTTTTTCAT ATGTGTTTCC TTAGTGCCTA3001GCAGACTATC TGTTCATAAT CAGTTTTCAG TGTGAATTCA CTGAATGTTT ATAGACAAAA3061GAAAATACAC ACTAAAACTA ATCTTCATTT TAAAAGGGTA AAACATGACT ATACAGAAAT3121TTAAATAGAA ATAGTGTATA TACATATAAA ATACAAGCTA TGTTAGGACC AAATGCTCTT3181TGTCTATGGA GTTATACTTC CATCAAATTA CATAGCAATG CTGAATTAGG CAAAACCAAC3241ATTTAGTGGT AAATCCATTC CTGGTAGTAT AAGTCACCTA AAAAAGACTT CTAGAAATAT3301GTACTTTAAT TATTTGTTTT TCTCCTATTT TTAAATTTAT TATGCAAATT TTAGAAAATA3361AAATTTGCTC TAGTTACACA CCTTTAGAAT TCTAGAATAT TAAAACTGTA AGGGGCCTCC3421ATCCCTCTTA CTCATTTGTA GTCTAGGAAA TTGAGATTTT GATACACCTA AGGTCACGCA3481GCTGGCTAGA TATACACCTG TCACAAGAGT CTAGATCAGT TAGCACATGC TTTCTACTCT3541TCGATTATTA GTATTATTAG CTAATGGTCT TTGGCATGTT TTTGTTTTTT ATTTCTGTTG3601AGATATAGCC TTTACATTTG TACACAAATG TGACTATGTC TTGGCAATGC ACTTCATACA3661CAATGACTAA TGTATACTGT GATGATTTGA CTCAAAAGGA GAAAAGAAAT TATGTAGTTT3721TCAATTCTGA TTCCTATTCA CCTTTTGTTT ATGAATGGAA AGCTTTGTGC AAAATATACA3781TATAAGCAGA CTAAGCCTTT TAAAAATGTT CTTTGAAAGA TAAAATTAAA TACATGAGTT3841TCTAACAATT ACAGENBANK ID: AAA62202.1DEFINITION HUMAN ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II MRNA,COMPLETECDS.VERSION U10117.1 GI:498909MRNA 1..1057CDS 50..988/CODON_START=11GGAACCCGTG GTCCTCCGCT TCATGATTTT CTGCCGTCTC TTGGCAAAAA TGGCAAATAA61TGATGCTGTT CTGAAGAGAC TGGAGCAGAA GGGTGCAGAC GCAGATCAAA TCATTGAATA121TCTTAAGCAG CAAGTTTCTC TACTTAAGGA GAAAGCAATT TTGCAGGCAA CTTTGAGGGA181AGAGAAGAAA CTTCGAGTTG AAAATGCTAA ACTGAAGAAA GAAATTGAAG AACTGAAACA241AGAGCTAATT CAGGCAGAAA TTCAAAATGG AGTGAAGCAA ATAGCATTPC CATCTGGTAC301TCCACTGCAC GCTAATTCTA TGGTTTCTGA AAATGTGATA CAGTCTACAG CAGTAACAAC361CGTATCTTCT GGTACCAAAG AACAGATAAA AGGAGGAACA GGAGACGAAA AGAAAGCGAA421AGAGAAAATT GAAAAGAAAG GAGAGAAGAA GGAGAAAAAA CAGCAATCAA TAGCTGGAAG481TGCCGACTCT AAGCCAATAG ATGTTTCCCG TCTGGATCTT CGAATTGGTT GCATCATAAC541TGCTAGAAAA CACCCTGATG CAGATTCTTT GTATGTCGAA GAAGTAGATG TCGGAGAAAT601AGCCCCAAGG ACAGTTGTCA GTGGCCTGGT GAATCATGTT CCTCTTGAAC AGATGCAAAA661TCGGATGGTG ATTTTACTTT GTAACCTGAA ACCTGCAAAG ATGAGGGGAG TATTATCTCA721AGCAATGGTC ATGTGTGCTA GTTCACCAGA GAAAATTGAA ATCTTGGCTC CTCCAAATGG781GTCTGTTCCT GGAGACAGAA TTACTTTTGA TGCTTTCCCA GGAGAGCCTG ACAAGGAGCT841GAATCCTAAG AAGAAGATTT GGGAGCAGAT CCAGCCTGAT CTTCACACTA ATGATGAGTG901TGTGGCTACA TACAAAGGAG TTCCCTTTGA GGTGAAAGGG AAGGGAGTAT GTAGGGCTCA961AACCATGAGC AACAGTGGAA TCAAATAAAA TGCTTCCACT ACCAAAAGAC ATTAGAGAAA1021ACCTTAAAAG TAATAAAGAG AAATATATTT GTCACTTGENBANK ID: P17936DEFINITION HUMAN ACIDIC FIBROELAST GROWTH FACTOR MRNA, 5′END, CLONELA64BDA-MJ36.CDS 358..>478/CODON_START=11TCCCCAAGGC TAGGAGGCCA ACCTACTAAC AGGTGGGTGG GTATGGTGTG TGGTTTCACT61CAGTTCTTCT CATGGGGTTT CTCTGAGCTC CATTCATACC AGAAAGGGAG CAGGAGAGAG121AGGACAAGTG GATCCAACAG CCTTCGCTCC AGGGGAATCA GGGCATCGCC TCCTTTTCTG181GGAGGACACT CCCTTCTGAT GGTGAATGGG AACTCCCTTC CTCCTGCAGC AGCCTGCCTG241CAGCTGTCCT GGTAGAACAG TGTGGACATT GCAGAAGCTG TCACTGCCCC AGAAAGAAAG301CACCCCAGAG CCAAGGCAAA GAGTCTTGAA AGCGCCACAA GCAGCAGCTG CTGAGCCATG361GCTGAAGGGG AAATCACCAC CTTCACAGCC CTGACCGAGA AGTTTAATCT GCCTCCAGGG421AATTACAAGA AGCCCAAACT CCTCTACTGT AGCAACGGGG GCCACTTCCT GAGGATCCGENBANK ID:U76376. 1VERSION U76376.1 GI:1923234MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMWRRRARSRRAPAPGALPTYWPWLCAAAQVAALAAWLLGRRNLGENBANK ID: Y00638VERSION Y00638.1 GI:34280MYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKNPSVPLSSDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQTPSAGTDTQTFSGSAANAKLNFTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNNIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYFGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRPFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVNVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNNKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFGRKVKVIVNLTELKHGDDEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEDLPAEPKELISNIQVVKQKLPQKNSSEGNKHHKSTPLLTHCRDGSQQTCIFCALLNLLESAETEEVVDIFQVVRALRKARLGMVSTFEQYQFLYDVIASTYPAQNQQVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPENSVNGPASPALNQGSGENBANK ID: AF001383.1VERSION AF001383.1 GI:2199534MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLDKADETKDEQFEQCVQNFNKQLTECTRLQKDLRTYLASVKANHEASKKLNECLQEVYEPDWFGRDEANKIAENNDLLNMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRQRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEENNVDLQEELPSLWNSRVGFYVNTEQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQNGSNTFTVKAQPSDNAPAKGNKSPSPEDGSPAATPEIRVNHEPEPAGGATPGATLFKSPSQLRKGPPVPPPFKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPCETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQEDYTATDTDELQLKAGDVVLVIPFQNFEEQDEGWLMGVKESDWNQHKELEKCRGVFFENFTERVPGENBANK ID: XM_038595.3VERSION XM_038595.3 GI:18590923MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSESFGDHLAEDLCVQAAKASGILPVYRSLFALATEDLSCWFPPSHIESVEDASTQVLLYRIREYEPNWEGLEKCNREGLRKDLASAILDLPVLEHLFAQERSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPSLRDLIQGLSPVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETEHVGLPGALGGHDGLGLLRVAGDGGIAWTQGEQEVLQPECDEFEIVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHEFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDEDSELLTVCVQNPLGPDYKGCLIRRSPTGTELLVGLSRPHSSLRELLATCNDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQVQLSQMTFEKIFADSLEWHENLGHGSETKIYRGCRHEVVDDEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCNAGDSTNVQEFVHLGAIDNYLRKRCHLVPASWKLQVVKQLAYALNYLEDKGLPNCNVSARKVLLAREGADGSPEFIELSDPCVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKNGFGATVWEVFSGVTNPISALDPAKKLQFYEDRQQLPAPKNTELALLIQQCNAYEPVQRPSERAVIRDLNSLISSDVELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNEQSVELCRVDFLGDNTGALVAVKQLQHSGPDQQRDEQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVNEYLPSGCLRDELQRHRARLDASRLLLYSSQICKGNEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAFESLSDNIESRQSDVWSFGVVLVELFTYCDKSCSPSAEFLRMNGCERDVPALCRLLELLEEGQRLPAPPACPAEVEELMKLCWAPSPQDRPSFSALDPQLDNLNSCSRGCETSAFTANPEGKHESLSFSGENEANK ID: M32292.1VERSION M32292.1 GI:181492MENSLRCVWVPKLAEVLECASLLSAHLQVTCFQIKAETALRELSEPSDAVTMRCGNVLLDCSAESDRGVFVIKWKKDGIHLALCMDERKQQLSNCSLLIQNILHSREHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRELSQTESVTAENGDTVLLKCEVIGEPMPTINNQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIVRCSARNPASSRTGNEAEVRICSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGVPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMVTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESNDIEFECTVSCKPVPTVNWMKNCDVVIPSDYFQIVCCSNLRILGVVKSDEGEYQCVAENEAGNAGTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSREVRLSWRPPAEAKCNIQTETVFFSREGDNRERALNTTQPGSLQLTVCNLKPEANVTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAVANGPVQCVRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRELAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGEITGYKIRHRKTTRRGENETLEPNNLWYLFTGLEKGSQYSFQVSANTVNCTCPPSNWYTAETPENDLDESQVPDQFSSLHVRPQTNCIIMSWTPPLNGENBANK ID: X06318VERSION X06318.1 GI:35488MADPAACFFPSEGEESTVRFARKGALRQKNVHEVKNHKETAREFKQPTFCSHCTDFIWCFGKQGEQCQVCCFVVHKRCNEFVTFSCPGADKGPASDDPRSKHKEKIHTYSSPTECDHCGSLLYGLIHQGMKCDTCMNNVHKRCVNNVPSLCCTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPNDPNGLSDPYVKLELIPDPKSESKQETETIKCSLNPEWNETFRFQLKESDKDRRLSVETWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVFEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKTLKKDVVTQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLNYNIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVNLDSEGHIRIADFCNCKENINDGVTTKTFCGTPDYIAPEIIAYQFYGKSVDWWAFGVLLYEMLAGQAFFEGEDEDELFQSIMEHNVAYFKSMSKEAVAICKGLMTKHFGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQFPYKPKARDKRDTSNFDKEFTRQPVELTFTDKLFIMNLDQNEFAGFSYTNPEFVINVGENBANK ID: J04122.1VERSION J04132.1 GI:623041MKWKALFTAAILQAQLFITEAQSFGLLDPELCYLLDGILFIYGVILTALFLRVKFSRSAEPPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAEAYSEIGNKGERRRGKGHDGLYQGLSTATKDTYDALHNQALPPRGENBANK ID: 004313.1VERSION 004313.1 GI:453368MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDIPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWNKKFPESETKECPFRLNKTDTKPVGMNNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGNSETKGVALSNVINKVCLEITEDGGDSIEVPGARILQHKDELNADHFFIYIIRHNKTRNIIFFGKFCSPGENBANK ID: X68968.1VERSION X68968.1 GI:452315MDEPSPLAQFLELNQHSRFIIGSVSEDNSEGEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHIRSSNSGLELVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVECMRSIRRWSYENFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVFGGFNNNNYANVELILDIAKRIFVQAVWAGWGHASENPKLPELLLKNGIAFNGPPSQANNALGDKIASSIVAQTAGIFTLFWSGSGLRVDWQENDFSKRILNVFQELYEKGYVKDVDDGLQAAEEVGYPVNIKASEGGGGEGIRKVNNAGDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATFAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDRSFYFLELNPRLQVEHFCTEMVADVNLFAAQLQIAMGIFLYRIKDIRMMYGVSFWGDSFIDFEDSAHVFCPRGHVIAARITSENFDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGESREEAISNNVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLEAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVINNGSCVEVDVHRLSDGGLLLSYDGSSYTTYNKEEVDRYRITIGNKTCVFEKENDPSVMRSFSAGKLIQYIVEDGGHVLAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLFDFFSSSKVKDWVERLNKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFNNTQSIVQLVQRYRSGIRGHMKAVVMDLLRGYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSEISIFDVLPNFFYNSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFNLPTSNPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMCGMVSFRTFEDFVRIFDEVNGCFSDSPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAANFREFTQQNKATLVDHGIRELTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRELEPALAFQLELNRMRNFDLTAIPCANEKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEANDELEVAFNNTNVRTDCNHIFLNFVPTVIMDFSKIEESVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGFQHGNLINTPYVTEDLLQAKREGAQTLGTTYIYDFFEMFRQALFKLWGSPDKYPKDILTYTELVLDSQGQLVENNRLFGGNEVGNVAFKMRFKTQEYFEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEAIFKIYVAANSGARIGMAEEIKHMFHVAWVDPEDFHKGFKYLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQINNYNGVSEITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLFSRAPYDPRWNLAGRFHFTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIKDFNREKLFLMIEANWRGFSGGNKDNYDQVLRFGAYTVDGLRQYKQPTLIYIRPMRELRGGSWVVIDATINFLCIENYADKESRGGVLEFEGTVEIKFRKEDLIKSMRRIDPAYKKLNEQLGEPDLSDKDRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGEMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQASGELSEVHIQSMLRRWFVETEGAVRAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISFAERAQVVHLLSTMDSPASTGENBANK ID: L03840.1VERSION L03840.1 GI:182570MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASELFEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEGPKSNRDPSNRNSYPQQAPYNTHPQRMEKKLHAVPAGNTVKFRCFAAGNPTPTIRWLKGGQAFHGENRIGGIRLRHQEWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYRGQALNGRHPRPPATVQKLSRFPLARQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHENIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGNQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHNIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRFFHCPFELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHDPLPLGSSSFPFGSGVQTGENBANK ID: AF043342.1VERSION AF043342.1 GI:2905633VRSSSRTPSDKPVANVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHITSRIAVSYQTKVNLLSAIKSPCQRETPRGAEAKPWYEPIYLCGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGITALGENBANK ID: NM_000735.2VERSION NM_000735.2 GI:10800407MDYYRKYAAIFLVTLSVFLNVLNSAPDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTNLVQKNVTSESTCCVAKSYNRVTVN0GFKVENHTACNCSTCYYNKSGENBANK ID: M83533.1VERSION M83533.1 GI:178541LRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRRENIKPFSLNFKDSSLENKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLANVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYA0LFLRYDNLNESGEDFLGTKEVSLLLMANFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARNELEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYNAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISNGSVVAGVIGAKKPQYDIMGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVEGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGNYNRRTLLSPSGTEPGAQAEGTDKSDLPGENBANK ID: M31767.1VERSION M31767.1 GI:181615MDKDCEMKRTTLDSPLGKLELSGCEQGLNEIKLLGKGTSAADAVEVPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGEVISYQQLAALAGNPKATRAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKENLLANEGNRLGKPGLGGSSGLAGAWLKGAGATSGSPPAGRNGENBANK ID: X14723VERSION X14723.1 GI:30250MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQTKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSFFYFWNNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLNPFSPYEPLNFHAMFQPFLEMTHEAQQAMDIHFESPAFQNPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVEVEVSRKNFKFMETVAEKALQEYRKKHREEGENBANK ID: X04391.1VERSION X04391.1 GI:37186MPMGSLQPLATLYLLGNLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDESQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSESRNDMCESLGLTCLEPQKTTFFTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEFRENQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCFHQKLSQCEELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRGKKQRQWIGPTGNNQNNSFHRNETATVRSHAENPTASHVDNEYSQFPRNSRLSAYFALEGVLNRSSNQPDNSSDSDYDLHGAQRLGENBANK ID: S78187.1VERSION S78187.1 GI:243485MEVPQPEPAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLGSPVRAAASSFVTTLTQTMHDLAGLGSRSRLTELSLSRRASESSLSSESSESSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSNPVRLLGHSPVLRNITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKNEVEELSPLALGRFSLTFAEGDTEEDDGFVDILESDLKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSFSNPCSVIRPILKRLERPQGRDTPVQNKRRRSVTPPEEQQEAEEEKARVLRSKSLCHDEIENDLLSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETNVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFNCEFSSERGPRMCRFIRERDRAVNDYFSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPNNHEAFKDELKTFRLKTRSWAGERSRRELCDRLQDQGENBANK ID: Y00096.1VERSION Y00096.1 GI:30455MREAAFMYSTAVAIFLVILVAALQGSAPRESPLPYEIPLDPEGSLELSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRQELENADLVVLWTDGDTAYFADAWSDQKGQIHLDFQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEAINGSGLQMGLQRVQLLKFNIFEPELFSDTCTNEVQAFNIQIESQETTYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRVLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGINELGLVYIPVMAIFPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSFHFQEIRMLKKVVSVHFGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKTAVDAGFLQKYFHLINRFNNEDVCTCFQASVSQQFTSVFWNSFNCDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKGGENBANK ID: XM_055551.3VERSION XM_055551.3 GI:18557356MKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYNTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMNAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDEVAAEEPSDAVPDEIFFLEQDEDASRMEEVDGENBANK ID: M84711.1VERSION M84711.1 GI:182774MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKCRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTNIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQEQQVRQIRKKMMEIMTREVQTNDLKEVVNKLTPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPKFELGKLMELRGEGSSSGKATGDETGAKVERADGYEPPVQESVGENBANK ID: X53505VERSION X53505.1 GI:36145MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVQASNCDEPMYVKLVEALLAEHQINLIKVDDNKKLGEWVGLCKIDREGNPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKKGENBANK ID: X06617VERSION X06617.1 GI:26143MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLFRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRFLSKTVRFNVLKVTKAAGTKKQFQKFGENBANK: M55040.1VERSION M55040.1 GI:177974MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPNGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMNNPNRELSEDCLYLNVWTPYPRPTSPTBVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSNNYRVGAFGFLALPGSREAPGNVGLLDGRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGNGEARRRATQLAHLVGCPBGGTGGNDTELVACLRTRPAQVLVNKEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDFARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIFLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDLGENBANK ID: NM_000717.2VERSION NM_000717.2 GI:9951925MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKNGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLDAPYQAKQLHLHWSDLPYKGSEHSLDGEHFANEMNIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLFKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLRREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLRGENBANK ID: S70S87.1VERSION S70587.1 GI:546848MTALFLMSNLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTMCAGYCNTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSVGENBANK ID: M34057VERSION M34057.1 GI:339547MDTKLMCLLFFFSLFPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCNNGGQCSSRDKCQCFFNFTGKLCQIPVHGASVPKLYQNSQGFGKALGTHVIHSTHTLPLTVTSGQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCFNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMYPLSVHLTKQLCCCSVGKAGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGARSAEPEVATAPPEKEIFSLDQEKTKLEPGQPQLSPGISAIHLHPQFPVVIEKTSPFVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQNLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSCYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEFNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQCNLCVNGQCKNTECSFRCTCGQGYQLSAAKDQCEDIDECQNRHLCAHGQCRNTEGSFQCVCDQGYRASGLCDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSEHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLCTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDFVKLQCFDNDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRFAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGNQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTFEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCLDGYHLDTAKNTCFDVNECDELNNRNSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLEGENBANK ID: AF257099.1VERSION AF257099.1 GI:8037944MSDAAVDTSSEITTEDLKEKKEVVEEAENGRDAFANGNANEENGEPEADNEVDEEEEEGGEEEGDGEEEDGDEDEGAESATGKRAAEDDEDDDVDTQKQKTDEDDGENBANK ID: L06505.1VERSION L06505.1 GI:186799MPFKFDFNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRRHPHDIIDDINSGAVECPASGENBANK ID: X79234.1VERSION X79234.1 GI:495125MAQDQGEKENPMRELRIRKLCLNICVGESGGRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVECAVRGAKAEEILEKGLKVRELELRKNNFSDTGNFGFGIQEHIDLGIEYDFSIGIYGLDFYVVLGRFGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGKGENBANK ID: X59932.1VERSION X59932.1 GI:30255MASIQAAWPSGTECIAKYNFHGTAEQDLPECKGDVLTIVAVIKDPNWYKAKNKVGREGIIFANYVGKREGVKAGTKLSLNPWFHGKITREQAERLLYPPETGLFLVRESTNYFGDYTLCVSCDGKVEHYRINYHASKLSIDEEVYFENLNQLVEHYTSDADGLCTRLIKFKVNEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVNLGDYRGNKVAVKCIKNDATAQAFLAEASVNTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEANEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKESTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVFRVEKGYKNDAFDGCPFAVYEVNKNCWHLDAANRFSFLQLREQLEHIKTHELHLGENBANK ID: AAA98616.1VERSION AAA98616.1 GI:1784281MQGPWVLLLL GLRLQLSLGI IPVEEENPDF WNRQAAEALG AAKKLQPAQT AAKNLIMFLG61DGMGVSTVTA ARILKGQKKD KLGPETFLAM DRFPYVALSK TYSVDKHVPD SGATATAYLC121GVKGNFQTIG LSAAARFNQC NTTRGNEVIS VVNRAKKAGK SVGVVTTTRV QHASPAGTYA181HTVNRNWYSD ADVPASARQE GCQDIATQLI SNMDIDVILG GGRKYMFPMG TPDPEYFDDY241SQGGTRLDGK NLVQEWLAKH QGARYVWNRT ELLQASLDPS VTHLMGLFEP GDMKYEIHRD301STLDPSLMEM TEAALLLLSR NPRGFFLFVE GGRIDHGNHE SRAYRALTET IMFDDATERA361GQLTSEEDTL SLVTADHSHV FSFGGYPLRG SSIFGLAPGK ARGRKAYTVL LYGNGRGYVL421KDGARFDVTE SESGSPEYRQ QSAVFLDGET HAGEDVAVFA RGPQAHLVHG VQEQTFIAHV481MAFAACLEPY TACDLAPPAG TTDAAHPGPS VVPALLPLLA GTLLLLGTAT APGENBANK ID: XM_041507.1VERSION XM_041507.1 GI:14727457MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVEQEKIIREDGVSEEECRQYRAVVYSNTIQSIEAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLFDDLSGVIRRLWADHGVQACFCRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKEFDVGGQRSERKKWIHCFEGVIAIIFCVALSAYDLVLAEDEEMNRNNESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEVTGANKYDEAASYIQSKFEDLNKRKDTKEIVTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLFGENBANK ID: NM_001032.2VERSION NM_001032.2 GI:13904868MGHQQLYESHPRKFGQGSRSCRVCSNRHGLIRKVGLNMCRQCFRQYAKDIGFIKLDGENBANK ID: M22430.1VERSION M22430.1 GI:190888MKTLLLLAVIMIFGLLQAHGNLVNFHRNIKLTTGKEAALSVGFYGCHCGVGGRGSPKDATDRCCVTNDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRCGENBANK ID: X63527VERSION X63527.1 GI:36127MSNLRLQKRLASSVLRC0KKKVELDPNETNEIANANSRQQIRKLIRDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTENRRMRILRRLLRRYRESKKIDRHNYHSLYLKVK0NVFKNKRILNEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLSKEEETKKGENBANK ID: AF099644.1VERSION AF099644.1 GI:4323527MAQFAFESDLHSLLQLDAPIPNAPPARWGRKAKEAAGFAFSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKFGGDRVIFHRSAAQMEVASFLLSKENQFENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKICRVIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVVLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSGEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGEVFLQTFTQHQGAVKAVAECPWQSNVLATGGGTSDRHIRIENVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIRGENBANK ID: X51466VERSION X51466.1 GI:31105MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFVELSENDLNFIKQSKDGAGFLINLIDSPGMVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGMAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDFANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMVISKNVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGFNYTFGKKEDLYLKPIQRTILMMGRYVEPIEDVFCGNIVGLVGVDGFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARVLAEKVEWDVAEARKIMCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVMDVTLMADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIVLVEIQCPEQVVGGIVGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKKGIPALDNFLDGENBANK ID: M15661VERSION M15661.1 GI:337577MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGRRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQFGENEANK ID: J04823.1VERSION J04823.1 GI:1311703MSVLTFLLLRGLTGSARRLPVPRAKIHSLPPEGKLGINELAVGLTSCFVTFLLPAGWILSHLETYRRPEGENBANK ID: NM_001760.2VERSION NM_001760.2 GI:16950657MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLANNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSFRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKABRGSSSQGPSQTSTPTDVTAIHLGENBANK ID: NM_002625.1DEFINITION HOMO SAPIENS 6-PHOSPHOFRUCTO-2-KINASEFRUCTOSE-2,6-BIPHOSPHA-TASE 1(PFKFB1), MRNA.VERSION NM_002625.1 GI:4505744CDS 80..14951GAATTCCGGA CAGGTAGTAA GATAGGAAGT GAGGCCAGGT ACCTTGTGGG CAGTGATGTC61ATTCGGTGCG ACTCCTAAGA TGTCTCCAGA GATGGGAGAG CTCACCCAAA CCAGGTTGCA121GAAGATCTGG ATTCCACACA GCAGCGGCAG CAGCAGGCTG CAACGGAGAA GGGGCTCATC181CATACCCCAG TTTACCAATT CCCCCACAAT GGTGATCATG GTGGGTTTAC CAGCTCGAGG241CAAGACCTAT ATCTCCACAA AGCTCACACG ATATCTCAAC TGGATAGGAA CACCAACTAA301AGTGTTTAAT TTAGGCCAGT ATCGACGAGA GGCAGTGAGC TACAAGAACT ATGAATTCTT361TCTTCCAGAC AACATGGAAG CCCTGCAAAT CAGGAAGCAG TGCGCCCTGG CAGCCCTGAA421GGATGTTCAC AACTATCTCA GCCATGAGGA AGGTCATGTT GCGGTTTTTG ATGCCACCAA481CACTACCAGA GPACGACGGT CACTGATCCT GCAGTTTGCA AAAGAACATG GTTACAAGGT541GTTTTTCATT GAGTCCATTT GTAATGACCC TGGCATAATT GCAGAAAACA TCAGGCAAGT601GAAACTTGGC AGCCCTGATT ATATAGACTG TGACCGGGAA AAGGTTCTGG AAGACTTTCT661AAAGAGAATT GAGTGCTATG AGGTCAACTA CCAACCCTTG GATGAGGAAC TGGACAGCCA721CCTGTCCTAC ATCAAGATCT TCGACGTGGG CACACGCTAC ATGGTGAACC GAGTGCAGGA781TCACATCCAG AGCCGCACAG TCTACTACCT CATGAATATC CATGTCACAC CTCGCTCCAT841CTACCTTTGC CGACATGGCG AGAGTGAACT CAACATCAGA GGCCGCATCG GAGGTGACTC901TGGCCTCTCA GTTCGCGGCA AGCAGTATGC CTATGCCCTG GCCAACTTCA TTCAGTCCCA961GGGCATCAGC TCCCTGAAGG TGTGGACCAG TCGCATGAAG AGGACCATCC AGACAGCTGA1021GGCCCTGGGT GTCCCCTATG AGCAGTGGAA GGCCCTGAAT GAGATTGATG CGGGTGTCTG1081TGAGGAGATG ACCTATGAAG AAATCCAGGA ACATTACCCT GAAGAATTTG CACTGCGAGA1141CCAAGATAAA TATCGCTACC GCTATCCCAA GGGAGAGTCC TATGAGGATC TGGTTCAGCG1201TCTGGAGCCA GTGATAATGG AGCTAGAACG ACAGGAGAAT GTACTGGTGA TCTGCCACCA1261GGCTGTCATG CGGTGCCTCC TGGCCTATTT CCTGGATAAA AGTTCAGATG AGCTTCCATA1321TCTCAAGTGC CCTCTGCACA CAGTGCTCAA ACTCACTCCT GTGGCTTATG GCTGCAAAGT1381GGAATCCATC TACCTGAATG TGGAGGCCGT GAACACACAC CGGGAGAAGC CTGAGAATGT1441GGACATCACC CGGGAACCTG AGGAAGCCCT GGATACTGTC CCAGCCCACT ACTGAGCGCT1501TTCCAAGAAG TCAAACTGCC TGTGTCCTCA TCGCCTTCCA CCTTTAGGAA ATGCTATCTT1561TGCTCTTCTC CTACTCTGCC TTGGCCTCAC TGAGGCACCC CACTTCCAGT GAAGAAGTCC1621TCCGCAACTC CCAAACAAGC CTCGCTTGCT GGCCGCAACC AAGGAGCTAT CTAGCTCTGG1681AGGAAACTTT CTTTCTTAAT TCCTATTCTC TGACGAATAA AGACTTACTG CCTACAAGAG1741GGENBANK ID: D00760DEFINITION HUMAN MRNA FOR PROTEASOME SUBUNIT HC3.VERSION D00760.1 GI:220023CDS 1..705/CODON_START=11ATGGCGGAGC GCGGGTACAG CTTTTCGCTG ACTACATTCA GCCCGTCTGG TAAACTTGTC61CAGATTGAAT ATGCTTTGGC TGCTCTAGCT GGAGGAGCCC CGTCCGTGGG AATTAAAGCT121GCAAATGCTG TGGTATTAGC AACTGAGAAA AAACAGAAAT CCATTCTGTA TGATGACCGA181AGTGTACACA AAGTAGAACC AATTACCAAG CATATAGGTT TGGTGTACAG TGGCATGGGC241CCCGATTACA GAGTGCTTGT GCACAGAGCT CGAAAACTAG CTCAACAATA CTATCTTGTG301TACCAAGAAC CCATTCCTAC AGCTCAGCTG GTACAGAGAG TAGCTTCTGP CATGCAAGAA361TATACTCAGT CAGGTGGTGT TCGTCCATTT GGAGTTTCTT TACTTATTTG TGGTTGGAAT421GACGGACCAC CATATTTATT TCAGTCAGAT CCATCTGGAG CTTACTTTGC CTGGAAAGCT481ACACCAATGG GAAAGAACTA TGTGAATCGG AAGACTTTCC TTGAGAAAAG ATATAATGAA541GATCTGGAAC TTGAAGATGC CATTCATACA GCCATCTTAA CCCTAAAGGA AAGCTTTGAA601GGGCAAATGA CAGAGGATAA CATAGAAGTT GGAATCTGCA ATGAAGCTGG ATTTAGGAGG661CTTACTCCAA CTGAAGTTAA GGATTACTTG GCTGCCATAG CATAACAATG AAGTGACTGA721AAAATCCAGA ATTTCAGATA ATCTATCTAC TTAAACATGT TTAAAGTATG TTTTGTTTTG781CAGACTTTTT GCATACTTAT TTCTACATGG TTTAAATCGA CTGTTTTTAA AATGACACTT841ATAAATCCTA ATAAACTGTT AAACCCGENBANK ID: P10644GENBANK ID: XM_043948.2DEFINITION HOMO SAPIENS ALDOLASE A, FRUCTOSE-BISPHOSPHATE (ALDOA), MRNA.VERSION XM_043948.2 GI:18585537CDS 243..1349/CODON_START=11AAAAACCAGG GCTCCAGAGA ATCAGAACAG CCACCATCAC CGCAGGGAGT CAAGGGAGGA61GGGAGATTAG AGAAGGAGCC AGGGAGGGTG GCAGGGAGGC CACGTGATCC GAGTCCCCTC121ACCCCTTTCC TTCCCACAGG TCCCTGGCCA AAGATTTATT TCTCTTGACA ACCAAGGGCC181TCCGTCTGGA TTTCCAAGGA AGAATTTCCT CTGAAGCACC GGAACTTGCT ACTACCAGCA241CCATGCCCTA CCAATATCCA GCACTGACCC CGGAGCAGAA GAAGGAGCTG TCTGACATCG301CTCACCGCAT CGTGGCACCT GGCAAGGGCA TCCTGGCTGC AGATGAGTCC ACTGGGAGCA361TTGCCAAGCG GCTGCAGTCC ATTGGCACCG AGAACACCGA GGAGAACCGG CGCTTCTACC421GCCAGCTGCT GCTGACAGCT GACGACCGCG TGAACCCCTG CATTGGGGGT GTCATCCTCT481TCCATGAGAC ACTCTACCAG AAGGCGGATG ATGGGCGTCC CTTCCCCCAA GTTATCAAAT541CCAAGGGCGG TGTTGTGGGC ATGAAGGTAG ACAAGGGCGT GGTCCCCCTG GCAGGGACAA601ATGGCGAGAC TACCACCCAA GGGTTGGATG GGCTGTCTGA GCGCTGTGCC CAGTACAAGA661AGGACGGAGC TGACTTCGCC AAGTGGCGTT GTGTGCTGAA GATTGGGGAA CACACCCCCT721CAGCCCTCGC CATCATGGAA AATGCCAATG TTCTGGCCCG TTATGCCAGT ATCTGCCAGC781AGGTGGGCCT GCAGAATGGC ATTGTGCCCA TCGTGGAGCC TGAGATCCTC CCTGATGGGG841ACCATGACTT GAAGCGCTGC CAGTATGTGA CCGAGAAGGT GCTGGCTGCT GTCTACAAGG901CTCTGAGTGA CCACCACATC TACCTGGAAG GCACCTTGCT GAAGCCCAAC ATGGTCACCC961CAGGCCATGC TTGCACTCAG AAGTTTTCTC ATGAGGAGAT TGCCATGGCG ACCGTCACAG1021CGCTGCGCCG CACAGTGCCC CCCGCTGTCA CTGGGATCAC CTTCCTGTCT GGAGGCCAGA1081GTGAGGAGGA GGCGTCCATC AACCTCAATG CCATTAACAA GTGCCCCCTG CTGAAGCCCT1141GGGCCCTGAC CTTCTCCTAC GGCCGAGCCC TGCAGGCCTC TGCCCTGAAG GCCTGGGGCG1201GGAAGAAGGA GAACCTGAAG GCTGCGCAGG AGGAGTATGT CAAGCGAGCC CTGGCCAACA1261GCCTTGCCTG TCAAGGAAAG TACACTCCGA GCGGTCAGGC TGGGGCTGCT GCCAGCGAGT1321CCCTCTTCGT CTCTAACCAC GCCTATTAAG CGGAGGTGTT CCCAGGCTGC CCCCAACACT1381CCAGGCCCTG CCCCCTCCCA CTCTTGAAGA GGAGGCCGCC TCCTCGGGGC TCCAGGCTGG1441CTTGCCCGCG CTCTTTCTTC CCTCGTGACA GTGGTGTGTG GTGTCGTCTG TGAATGCTAA1501GTCCATCACC CTTTCCGGCA CACTGCCAAA TAAACAGCTA TTTAAGGGGGGENBANK ID: NM_005175.1DEFINITION HOMO SAPIENS ATP SYNTHASE, H+TRANSPORTING, MITOCHONDRIAL F0COMPLEX, SUBUNIT C (SUBUNIT 9), ISOFORM 1 (ATP5G1), MRNA.VERSION NM_005175.1 GI:4885080CDS 120..530/CODON_START=11GGGGAAGCTG AGGGCTGAGA CCAAGGGCTA AAGCTGGGAG GTGAGTCTGT CACCTTGAGC61CGGGCGAGCG CTGTGGGCCA AGCAGGGGTT GCAGGGCAGT AGGAGTGCAG ACTGAAAAAA121TGCAGACCGC CGGGGCATTA TTCATTTCTC CAGCTCTGAT CCGCTGTTGT ACCAGGGGTC181TAATCAGGCC TGTGTCTGCC TCCTTCTTGA ATAGCCCAGT GAATTCATCT AAACAGCCTT241CCTACAGCAA CTTCCCACTC CAGGTGGCCA GACGGGAGTT CCAGACCAGT GTTGTCTCCC301GGGACATTGA CACAGCAGCC AAGTTTATTG GTGCTGGGGC AGCCACAGTT GGTGTGGCTG361GTTCAGGGGC TGGCATTGGA ACCGTGTTTG GCAGCTTGAT CATTGGCTAT GCCAGGAACC421CGTCTCTCAA GCAGCAGCTC TTCTCCTATG CCATTCTTGG CTTTGCCCTG TCTGAGGCCA481TGGGGCTTTT CTGTTTGATG GTCGCCTTCC TCATCCTCTT CGCCATGTGA GGCTCCATGG541GGGGTCACCG GCCTGTTGCT ACTGCAACTC CACACCATTC TTGGTGCTGC GGTGTGTTAA601GCTTTACCAT TAAACACAAC GTTTCTCTAA AGENBANK ID: M20496.1DNA LINEARDEFINITION HUMAN CATHEPSIN L GENE, COMPLETE CDS.VERSION M20496.1 GI:809235CDS 134..1135/CODON_START=11ACCTCCACGT GCCCTGTTTT TCTGGAGGCA CATCCTTGGC CTCTTCCACA GTCCTTGGGT61AAATGCTTGG GAGAATAATT TAAATATTTT TATTGTACCA TGGTGGCCCT AATTTTTCAG121GGGGCAGTAA GATATGAATC CTACACTCAT CCTTGCTGCC TTTTGCCTGG GAATTGCCTC181AGCTACTCTA ACATTTGATC ACAGTTTAGA GGCACAGTGG ACCAAGTGCA AGGCGATGCA241CAACAGATTA TACGGCATGA ATGAAGAAGG ATGGAGGAGA GCAGTGTGGG AGAAGAACAT301GAAGATGATT GAACTGCACA ATCAGGAATA CAGGGAAGGG AAACACAGCT TCACAATGGC361CATGAACGCC TTTGGAGACA TGACCAGTGA AGAATTCAGG CAGGTGATGA ATGGCTTTCA421AAACCGTAAG CCCAGGAAGG GGAAAGTGTT CCAGGAACCT CTGTTTTATG AGGCCGCCAG481ATCTGTGGAT TGGAGAGAGA AAGGCTACGT GACTCCTGTG AAGAATCAGG GTCAGTGTGG541TTCTTGTTGG GCTTTTAGTG CTACTGGTGC TCTTGAAGGA CAGATGTTCC GGAAAACTGC601GAGGCTTATC TCACTGAGTG AGCAGAATCT GGTAGACTGC TCTGGGCCTC AAGGCAATGA661AGGCTGCAAT GGTGGCCTAA TGGATTATGC TTTCCAGTAT GTTCAGGATA ATGGAGGCCT721GGACTCTGAG GAATCCTATC CATATGAGGC AACAGAAGAA TCCTGTAAGT ACAATCCCAA781GTATTCTGTT GCTAATGACA CCGGCTTTGT GGACATCCCT AAGCAGGAGA AGGCCCTGAT841GAAGGCAGTT GCAACTGTGG GGCCCATTTC TGTTGCTATT GATGCAGGTC ATGAGTCCTT901CCTGTTCTAT AAAGAAGGCA TTTATTTTGA GCCAGACTGT AGCAGTGAAG ACATGGATCA961TGGTGTGCTG GTGGTTGGCT ACGGATTTGA AAGCACAGAA TCAGATAACA ATAAATATTG1021GCTGGTGAAG AACAGCTGGG GTGAAGAATG GGGCATGGGT GGCTACGTAA AGATGGCCAA1081AGACCGGAGA AACCATTGTG GAATTGCCTC AGCAGCCAGC TACCCCACTG TGTGAGCTGT1141GGACGGTGAT GAGGAAGGAC TTGACTGGGG ATGGCGCATG CATGGGAGGA ATTCTTCAGT1201CTACCAGCCC CCGCTGTGTC GGATACACAC TCGAATCATT GAAGATCCGA GTGTGATTTG1261AATTCTGTGA TATTTTCACA CTGGTAAATG TTACCTCTAT TTTAATTACT GCTATAAATA1321GGTTTATATT ATTGATTCAC TTACTGACTT TGCATTTTCG TTTTTAAAAG GATGTATAAA1381TTTTTACCTG TTTAAATAAA ATCGGENBANK ID: XM_031596.3DEFINITION HOMO SAPIENS ANNEXIN A4 (ANXA4), MRNA.VERSION XM_031596.3 GI:18553329CDS 48..770/CODON_START=11GAAGAACTTC TGCTTGGGTG GCTGAACTCT GATCTTGACC TAGAGTCATG GCCATGGCAA61CCAAAGGAGG TACTGTCAAA GCTGCTTCAG GATTCAATGC CATGGAAGAT GCCCAGACCC121TGAGGAAGGC CATGAAAGGG CTCGGCACCG ATGAAGACGC CATTATTAGC GTCCTTGCCT181ACCGCAACAC CGCCCAGCGC CAGGAGATCA GGACAGCCTA CAAGAGCACC ATCGGCAGGG241ACTTGATAGA CGACCTGAAG TCAGAACTGA GTGGCAACTT CGAGCAGGTG ATTGTGGGGA301TGATGACGCC CACGGTGCTG TATGACGTGC AAGAGCTGCG AAGGGCCATG AAGGGAGCCG361GCACTGATGA GGGCTGCCTA ATTGAGATCC TGGCCTCCCG GACCCCTGAG GAGATCCGGC421GCATAAGCCA AACCTACCAG CAGCAATATG GACGGAGCCT TGAAGATGAC ATTCGCTCTG481ACACATCGTT CATGTTCCAG CGAGTGCTGG TGTCTCTGTC AGCTGGTGGG AGGGATGAAG541GAAATTATCT GGACGATGCT CTCGTGAGAC AGGATGCCCA GGACCTGTAT GAGGCTGGAG601AGAAGAAATG GGGGACAGAT GAGGTGAAAT TTCTAACTGT TCTCTGTTCC CGGAACCGAA661ATCACCTGTT GCATGGTTTG ATGAATACAA AAGGATATCA CAGAAGGATA TTGAACAGAG721TATTAAATCT GAAACATCTG GTAGCTTTGA AGATGCTCTG CTGGCTATAG TAAAGTGCAT781GAGGAACAAA TCTGCATATT TTGCTGAAAA GCTCTATAAA TCGATGAAGG GCTTGGGCAC841CGATGATAAC ACCCTCATCA GAGTGATGGT TTCTCGAGCA GAAATTGACA TGTTGGATAT901CCGGGCACAC TTCAAGAGAC TCTATGGAAA GTCTCTGTAC TCGTTCATCA AGGGTGACAC961ATCTGGAGAC TACAGGAAAG TACTGCTTGT TCTCTGTGGA GGAGATGATT AAAATAAAAA1021TCCCAGAAGG ACAGGAGGAT TCTCAACACT TTGAATTTTT TTAACTTCAT TTTTCTACAC1081TGCTATTATC ATTATCTCAG AATGCTTATT TCCAATTAAA ACCGCTACAG CTGCCTCCTA1141GAATATAGAC TGTCTGTATT ATTATTGACG TATAATTAGT CATTATGATG CTTTAAAGCT1201GTACTTGCAT TTCAAAGCTT ATAAGATATA AATGGAGATT TTAAAGTAGA AATAAATATG1261TATTCCATGT TTTTAAAAGA TTACTTTCTA CTTTGTCTTT CACAGACATT GAATATATTA1321AATTATTCCA TATTTTCTTT TCAGTGAAAA ATTTTTTAAA TGGAAGACTG TTCTAAAATC1381ACTTTTTTCC CTAATCCAAT TTTTAGAGTG GCTAGTAGTT TCTTCATTTG AAATTGTAAG1441CATCCGGTCA GTAAGAATGC CCATCCAGTT TTCTATATTT CATAGTCAAA GCCTTGAAAG1501CATCTACAAA TCTCTTTTTT TAGGTTTTGT CCATAGCATC AGTTGATCCT TACTAAGTTT1561TTCATGGGAG ACTTCCTTCA TCACATCTTA TGTTGAAATC ACTTTCTGTA GTCAAAGTAT1621ACCAAAACCA ATTTATCTGA ACTAAATTCT AAAGTATGGT TATACAAACC ATATACATCT1681GGTTACCAAA CATAAATGCT GAACATTCCA TATTATTATA GTTAATGTCT TAATCCAGCT1741TGCAAGTGAA TGGAAAAAAA AATAAGCTTC AAACTAGGTA TTCTGGGAAT GATGTAATGC1801TCTGAATTTA GTATGATATA AAGAAAACTT TTTTGTGCTA AAAATACTTT TTAAAATCAA1861TTTTGTTGAT TGTAGTAATT TCTATTTGCA CTGTGCCTTT CAACTCCAGA AACATTCTGA1921AGATGTACTT GGATTTAATT AAAAAGTTCA CTTTGTGENBANK ID: M22865.1DEFINITION HUMAN CYTOCHROME B5 MRNA, COMPLETE CDS.VERSION M22865.1 GI:18122653..457CODON_START=11CAGCCAGCTC GACGGGGCTG TGTGTGCTGG GCCTGGCTCG CGGCGAACCG AGATGGCAGA61GCAGTCGGAC GAGGCCGTGA ACTACTACAC CCTAGAGGAG ATTCAGAAGC ACAACCACAG121CAAGAGCACC TGGCTGATCC TGCACCACAA GGTGTACGAT TTGACCAAAT TTCTGGAAGA181GCATCCTGGT GGGGAAGAAG TTTTAAGGGA ACAAGCTGGA GGTGACGCTA CTGAGAACTT241TGAGGATGTC GGGCACTCTA CAGATGCCAG GGAAATGTCC AAAACATTCA TCATTGGGGA301GCTCCATCCA GATGACAGAC CAAAGTTAAA CAAGCCTCCG GAAACTCTTA TCACTACTAT361TGATTCTAGT TCCAGTTGGT GGACCAACTG GGTGATCCCT CCCATCTCTG CAGTGGCCGT421CGCCTTGATG TATCGCCTAT ACATGGCAGA GGACTGAACA CCTCCTCAGA AGTCAGCGCA481GGCCGAGCCT GCTTTGGACA CGGGAGAAAA GAAGCCATTG CTAACTACTT CAACTGACAG541AAACCTTCAC TTGAAAACAA TGATTTTAAT ATATCTCTTT CTTTTTCTTC CGACATTAGA601AACAAAACAA AAAGAACTGT CCTTTCTGCG CTCAAATTTT TCGAGTGTGC CTTTTTATTC661ATCTACTTTA TTTTGATGTT TCCTTAATGT GTAATTTACT TATTATAAGC ATCATCTTTT721AAAAATATAT TTGGCTTTTA AAGGENBANK ID: M14362.1DEFINITION HUMAN T-CELL SURFACE ANTIGEN CD2 (T11) MRNA, COMPLETE CDS.VERSION M14362.1 GI:179133CDS 10..1065/CODON_START=11ACCCCTAAGA TGAGCTTTCC ATGTAAATTT GTAGCCAGCT TCCTTCTGAT TTTCAATGTT61TCTTCCAAAG GTGCAGTCTC CAAAGAGATT ACGAATGCCT TGGAAACCTG GGGTGCCTTG121GGTCAGGACA TCAACTTGGA CATTCCTAGT TTTCAAATGA GTGATGATAT TGACGATATA181AAATGGGAAA AAACTTCAGA CAAGAAAAAG ATTGCACAAT TCAGAAAAGA GAAAGAGACT241TTCAAGGAAA AAGATACATA TAAGCTATTT AAAAATGGAA CTCTGAAAAT TAAGCATCTG301AAGACCGATG ATCAGGATAT CTACAAGGTA TCAATATATG ATACAAAAGG AAAAAATGTG361TTGGAAAAAA TATTTGATTT GAAGATTCAA GAGAGGGTCT CAAAACCAAA GATCTCCTGG421ACTTGTATCA ACACAACCCT GACCTGTGAG GTAATGAATG GAACTGACCC CGAATTAAAC481CTGTATCAAG ATGGGAAACA TCTAAAACTT TCTCAGAGGG TCATCACACA CAAGTGGACC541ACCAGCCTGA GTGCAAAATT CAAGTGCACA GCAGGGAACA AAGTCAGCAA GGAATCCAGT601GTCGAGCCTG TCAGCTGTCC AGAGAAAGGT CTGGACATCT ATCTCATCAT TGGCATATGT661GGAGGAGGCA GCCTCTTGAT GGTCTTTGTG GCACTGCTCG TTTTCTATAT CACCAAAAGG721AAAAAACAGA GGAGTCGGAG AAATGATGAG GAGCTGGAGA CAAGAGCCCA CAGAGTAGCT781ACTGAAGAAA GGGGCCGGAA GCCCCACCAA ATTCCAGCTT CAACCCCTCA GAATCCAGCA841ACTTCCCAAC ATCCTCCTCC ACCACCTGGT CATCGTTCCC AGGCACCTAG TCATCGTCCC901CCGCCTCCTG GACACCGTGT TCAGCACCAG CCTCAGAAGA GGCCTCCTGC TCCGTCGGGC961ACACAAGTTC ACCAGCAGAA AGGCCCGCCC CTCCCCAGAC CTCGAGTTCA GCCAAAACCT1021CCCCATGGGG CAGCAGAAAA CTCATTGTCC CCTTCCTCTA ATTAAAAAAG ATAGAAACTG1081TATTTTTCAA TAAAAAGCAC TGTGGATTTC TGCCCTCCTG ATGTGCATAT CCGTACTTCC1141ATGAGGTGTT TTCTGTGTGC AGAACATTGT CACCTCCTGA GGCTGTGGGC CACAGCCACC1201TCTGCATCTT CGAACTCAGC CATGTGGTCA ACATCTGGAG TTTTTGGTCT CCTCAGAGAG1261CTCCATCACA CCAGTAAGGA GAAGCAATAT AAGTGTGATT GCAAGAATGG TAGAGGACCG1321AGCACAGAAA TCTTAGAGAT TTCCTGTCCC CTCTCAGGTC ATGTGTAGAT GCGATAAATC1381AAGTGATTGG TGTGCCTGGG TCTCACTACA AGCAGCCTAT CTGCTTAAGA GACTCTGGAG1441TTTCTTATGT GCCCTGGTGG ACACTTGCCC ACCATCCTGT GAGTAAAAGT GAAATAAAAG1501CTTTGACTAGGENBANK ID: XM_087746.1DEFINITION HOMO SAPIENS SIMILAR TO KIDNEY ANINOPEPTIDASE N; LEUCINEARYLANINOPEPTIDASE 1 (LOC153726), MRNA.VERSION XM_087746.1 GI:18561749CDS 262..639/CODON_START=11GAGTTCCATG CCACCTCCCC GCCCTTTACA GACATGCTAT AAGGTCCCCA GCCCAGTCAC61TCCGCAGTGC CTCTCTCTTC CTCCCCATGG ACTATACACA GGCCCTGCTT GTCCTGGAGG121AAAGTTTGGA CGTCATTATA TAGAICAGGA GACTGAAGTA CTGAAAGGTT AAATGACTTG181CCAAAGAATG AGATCTTTTT TTCTAACATT TTACATAATA TCCTCAGAGA AGATCACGCC241CTGGTGACTA GAGCTGTGGC CATGAAGGTG GAAAATTTCA AAACAAGTGA AATACAGGAA301CTCTTTGACA TATTTACTTA CAGCAAGGGA GCGTCTATGG CCCGGATGCT TTCTTGTTTC361TTGAATGAGC ATTTATTTGT CAGTGCACTC AAGTCATATT TGAAGACATT TTCCTACTCA421AACGCTGAGC AAGATGATCT ATGGAGGCAT TTTCAAATGG CCATAGATGA GCAGACTACA481GTTATTTTGC CAGCAACAAT AAAAAACATA ATGGACAGGT GGACACACCA GAGTGGTTTT541CCAGTGATCA CTTTAAATGT GTCTACTGGC GTCATGAAAC AGGAGCCATT TTATCTTGAA601AACATTAAAA ATCGGACTCT TCTAACCAGC AATAAGTGAC ACATGGATTG TCCCTATTCT661TTGGATAAAA AATGGAACTA CACAACCTTT AGTCTGGCTA GAGENBANK ID: P31749DEFINITION DICTYOSTELION DISCOIDEUM RAC-ALPHA SERINETHREONINE KINASEHOMOLOGMRNA, COMPLETE CDS.VERSION PU15210.1 GI:1000068CDS 1..1335/CODON_START=11ATGTCAACAG CACCAATTAA ACATGAAGGT TTCCTCACTA AAGAAGGTGG TGGTTTCAAA61AGTTGGAAAA AGAGATGGTT CATTCTCAAA GGTGGTGATT TAAGTTATTA TAAAACAAAA121GGTGAACTTG TACCATTAGG AGTTATTCAT TTAAATACAT CAGGTCATAT TAAAAATTCT181GATCGTAAGA AAAGAGTTAA TGGATTTGAA GTACAAACAC CATCACGTAC ATATTTCTTA241TGTTCAGAGA CAGAGGAAGA ACGTGCAAAA TGGATAGAGA TATTAATTAA TGAAAGAGAA301TTATTATTGA ATGGTGGTAA ACAACCAAAG AAATCGGAAA AGGTAGGAGT TGCAGATTTT361GAATTATTGA ATTTAGTTGG TAAAGGTAGT TTTGGTAAAG TTATTCAAGT TAGAAAGAAA421GATACTGGTG AAGTGTATGC AATGAAAGTT TTATCAAAGA AACATATCGT AGAGCATAAC481GAAGTCGAAC ATACATTGAG TGAGCGTAAT ATTCTTCAAA AGATCAATCA CCCATTTTTG541GTTAATCTCA ACTACAGTTT TCAAACAGAG GATAAGCTTT ACTTTATCTT GGATTATGTT601AATGGTGGTG AGTTATTCTA TCATCTTCAA AAGGACAAAA AGTTTACAGA GGATCGTGTC661CGTTATTATG GCGCAGAGAT CGTATTGGCA TTGGAACATT TACATTTGTC GGGTGTCATC721TATAGAGATT TGAAACCAGA GAATTTACTA CTCACCAACG AGGGTCACAT TTGCATGACC781GATTTCGGTC TTTGCAAAGA GGGTCTATTG ACACCAACCG ACAAAACTGG TACTTTCTGT841GGTACTCCTG AATATTTAGC ACCCGAAGTA CTTCAAGGCA ATGGTTATGG TAAACAAGTG901GATTGGTGGA GTTTTGGTTC TCTCCTCTAT GAAATGCTCA CTGGTTTACC ACCATTCTAC961AATCAAGACG TCCAAGAGAT GTATCGTAAG ATCATGATGG AGAAATTATC TTTCCCACAT1021TTCATTTCTC CAGATGCTCG TTCCCTCTTG GAACAACTCT TGGAAAGAGA TCCTGAAAAA1081AGACTTGCCG ATCCAAATCT TATTAAAAGA CATCCTTTCT TCCGTTCCAT CGATTGGGAA1141CAATTATTCC AAAAGAATAT TCCACCACCA TTCATTCCAA ATGTTAAAGG TTCTGCTGAT1201ACCTCTCAAA TTGATCCAGT TTTCACTGAT GAAGCTCCTT CTTTAACTAT GGCTGGTGAA1261TGTGCTTTAA ATCCGCAACA ACAAAAAGAT TTTGAAGGAT TTACATATGT CGCTGAATCT1321GAACATTTAA GATAAGENBANK ID: NM_000102.2DEFINITION HOMO SAPIENS CYTOCEROME P450, SUBFANILY XVII (STEROID17-ALPHA--HYDROXYLASE), ADRENAL HYPERPLASIA (CYP17), MRNA.VERSION NM_000102.2 GI:13904854CDS 61..15871GAGTTGCCAC AGCTCTTCTA CTCCACTGCT GTCTATCTTG CCTGCCGGCA CCCAGCCACC61ATGTGGGAGC TCGTGGCTCT CTTGCTGCTT ACCCTAGCTT ATTTGTTTTG GCCCAAGAGA121AGGTGCCCTG GTGCCAAGTA CCCCAAGAGC CTCCTGTCCC TGCCCCTGGT GGGCAGCCTG181CCATTCCTCC CCAGACATGG CCATATGCAT AACAACTTCT TCAAGCTGCA GAAAAAATAT241GGCCCCATCT ATTCTGTTCG TATGGGCACC AAGACTACAG TGATTGTCGG CCACCACCAG301CTGGCCAAGG AGGTGCTTAT TAAGAAGGGC AAGGACTTCT CTGGGCGGCC TCAAATGGCA361ACTCTAGACA TCGCGTCCAA CAACCGTAAG GGTATCGCCT TCGCTGACTC TGGCGCACAC421TGGCAGCTGC ATCGAAGGCT GGCGATGGCC ACCTTTGCCC TGTTCAAGGA TGGCGATCAG481AAGCTGGAGA AGATCATTTG TCAGGAAATC ACTACATTGT GTGATATGCT GGCCACCCAC541AACGGACAGT CCATAGACAT CTCCTTTCCT GTCTTCGTGG CGGTAACCAA TGTCATCTCC601TTGATCTGCT TCAATACCTC CTACAAGAAT GGCGACCCTG AGTTGAATGT CATACAGAAT661TACAATGAAG GCATCATAGA CAACCTCAGC AAACACAGCC TGCTGGACCT AGTCCCCTGG721TTGAAGATTT TCCCCAACAA AACCCTGGAA AAATTAAAGA GCCATGTTAA AATACGAAAT781GATCTGCTGA ATAAAATACT TGAAAATTAC AAGGAGAAAT TCCGGAGTGA CTCTATCACC841AACATGCTGG ACACACTGAT CCAAGCCAAG ATGAACTCAG ATAATGGCAA TGCTGGCCCA901GATCAAGATT CAGAGGTGCT TTCAGATAAC CACATTCTCA CCACCATAGG GGACATCTTT961GGGGCTGGCG TGGAGACCAC CACCTCTGTG GTTAAATGGA CCCTGGCCTT CCTGCTGCAC1021AATCCTCAGG TGAAGAAGAA GCTCTACGAG GAGATTGACC AGAATGTGGG TTTCAGCCGC1081ACACCAACTA TCAGTGACCG TAACCGTCTC CTCCTGCTGG AGGCCACCAT CGGAGAGGTG1141CTTCGCCTCA GGCCCGTGGC CCCTATGCTC ATCCCCCACA AGGCCAACGT TGACTCCAGC1201ATCGGTGAGT TTGCTGTGGA CAAGGGCACA GAAGTTATCA TCAATCTGTG GGCGCTGCAT1261CACAATGAGA AGGAGTGGCA CCAGCCGGAT CAGTTCATGC CTGAGCGTTT CTTGAATCCA1321GCGGGGACCC AGCTCATCTC ACCGTCAGTA AGCTATTTGC CCTTCGGAGC AGGACCTCGC1381TCCTGTATAG GTGAGATCCT GGCCCGCCAG GAGCTCTTCC TCATCATGGC CTGGCTGCTG1441CAGAGGTTCG ACCTGGAGGT GCCAGATGAT GGGCAGCTGC CCTCCCTGGA AGGCATCCCC1501AAGGTGGTCT TTCTGATCGA CTCTTTCAAA GTGAAGATCA AGGTGCGCCA GGCCTGGAGG1561GAAGCCCAGG CTGAGGGTAG CACCTAAAGG CTGTAACTCA CAGCCCCTGT CCACCCTATG1621TGGCCCCACA ACACAGATTT AGAGATACAA CCCCCCACCC TTCTCCGCCA TTCTTCCCTA1681CTCCCAACCC ACTCTGCCTT CTTTTTCAGC TTGTGGCAAT GCCAGTGATG TGCATAAACA1741GTTTTTTTTT TTTCCGENBANK ID: NM_001662DEFINITION HOMO SAPIENS ADP-RIBOSYLATION FACTOR 5 (ARF5), MRNA.VERSION NM_001662.2 GI:6995999CDS 37..579/CODON_START=11CCGCGTCGGT GCCCGCGCCC CTCCCCGGGC CCCGCCATGG GCCTCACCGT GTCCGCGCTC61TTTTCGCGGA TCTTCGGGAA GAAGCAGATG CGGATTCTCA TGGTTGGCTT GGATGCGGCT121GGCAAGACCA CAATCCTGTA CAAACTGAAG TTGGGGGAGA TTGTCACCAC CATCCCAACC181ATAGGCTTCA ATGTAGAAAC AGTGGAATAT AAGAACATCT GTTTCACAGT CTGGGACGTG241GGAGGCCAGG ACAAGATTCG GCCTCTGTGG CGGCACTACT TCCAGAACAC TCAGGGCCTC301ATCTTTGTGG TGGACAGTAA TGACCGGGAG CGGGTCCAAG AATCTGCTGA TGAACTCCAG361AAGATGCTGC AGGAGGACGA GCTGCGGGAT GCAGTGCTGC TGGTATTTGC CAACAAGCAG421GACATGCCCA ACGCCATGCC CGTGAGCGAG CTGACTGACA AGCTGGGGCT ACAGCACTTA481CGCAGCCGCA CGTGGTATGT CCAGGCCACC TGTGCCACCC AAGGCACAGG TCTGTACGAT541GGTCTGGACT GGCTGTCCCA CGAGCTGTCA AAGCGCTAAC CAGCCAGGGG CAGGCCCCTG601ATGCCCGGAA GCTCCTGCGT GCATCCCCGG GATGACCAGA CTCCCGGACT CCTCAGGCAG661TGCCCTTTCC TCCCACTTTT CCTCCCCCAT AGCCACAGGC CTCTGCTCCT GCTCCTGCCT721GCATGTTCTC TCTGTTGTTG GAGCCTGGAG CCTTGCTCTC TGGGCACAGA GGGGTCCACT781CTCCTGCCTG CTGGGACCTA TGGAAGGGGC TTCCTGGCCA AGGCCCCCTC TTCCAGAGGA841GGAGCAGGGA TCTGGGTTTC CTTTTTTTTT TCTGTTTTGG GTGTACTCTA GGGGCCAGGT901TGGGAGGGGG AAGGTGAGGG CTTCGGGTGG TGCTATAATG TGGCACTGGA TCTTGAGTAA961TAAATTTGCT GTGGTTTGGENBANK 10: XM_048886.3DEFINITION HOMO SAPIENS MICROSOMAL GLUTATHIONE 5-TRANSFERASE 1(MGST1), MRNA.VERSION XM_048886.3 GI:18580621CDS 89..556/CODON_START=11AGTCCCTGCA TTGCGCGCGA CCCGGCGGCG GGACAGGCTT GCTGCTTCCT CCTCCTCGGC61CTCACCATTC CAGACCAAAA TTGAAAAAAT GGTTGACCTC ACCCAGGTAA TGGATGATGA121AGTATTCATG GCTTTTGCAT CCTATGCAAC AATTATTCTT TCAAAAATGA TGCTTATGAG181TACTGCAACT GCATTCTATA GATTGACAAG AAAGGTTTTT GCCAATCCAG AAGACTGTGT241AGCATTTGGC AAAGGAGAAA ATGCCAAGAA GTATCTTCGA ACAGATGACA GAGTAGAACG301TGTACGCAGA GCCCACCTGA ATGACCTTGA AAATATTATT CCATTTCTTG GAATTGGCCT361CCTGTATTCC TTGAGTGGTC CCGACCCCTC TACAGCCATC CTGCACTTCA GACTATTTGT421CGGAGCACGG ATCTACCACA CCATTGCATA TTTGACACCC CTTCCCCAGC CAAATAGAGC481TTTGAGTTTT TTTGTTGGAT ATGGAGTTAC TCTTTCCATG GCTTACAGGT TGCTGAAAAG541TAAATTGTAC CTGTAAAGAA AATCATACAA CTCAGCATCC AGTTGGCTTT TTAAGAATTC601TGTACTTCCA ATTTATAATG AATACTTTCT TAGATTTTAG GTAGGAGGGG AGCAGAGGAA661TTATGAACTG GGGTAAACCC ATTTTGAATA TTAGCATTGC CAATATCCTG TATTCTTGTT721TTACATTTGG ATTAGAAATT TAACATAGTA ATTCTTAAGT CTTTTGTCTG ATTTTTAAAG781TACTTTCTTA TAAATTTGGA TCATGTTATG ATTTGTAACA TTCACACAAC ACCTCACTTT841TGAATCTATA AAAGAATTGC ACGTATGAGA AACCTATATT TCAATACTGC TGAAACAGAC901ATGAAATAAA GAATTTAAAG AATGGENBANK ID: X02162DEFINITION HUMAN MRNA FOR AFOLIPOPROTEIN AI (APO AI)=.VERSION X02162.1 GI:28771CDS 87..890/CODON_START=11GAATTCAAAA AAAAAAGAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAGAG AGACTGCGAG61AAGGAGGTCC CCCACGGCCC TTCAGGATGA AAGCTGCGGT GCTGACCTTG GCCGTGCTCT121TCCTGACGGG GAGCCAGGCT CGGCATTTCT GGCAGCAAGA TGAACCCCCC CAGAGCCCCT181GGGATCGAGT GAAGGACCTG GCCACTGTGT ACGTGGATCT GCTCAAAGAC AGCGGCAGAG241ACTATGTGTC CCAGTTTGAA GGCTCCGCCT TGGGAAAACA GCTAAACCTA AAGCTCCTTG301ACAACTGCGA CAGCCTGACC TCCACCTTCA GCAAGCTGCG CGAACAGCTC GGCCCTGTGA361CCCAGGAGTT CTGGGATAAC CTGGAAAAGG AGACAGAGGG CCTGAGGCAG GAGATGAGCA421AGGATCTGGA GGAGGTGAAG GCCAAGGTGC AGCCCTACCT GGACGACTTC CAGAAGAAGT481GGCAGGAGGA GATGGAGCTC TACCGCCAGA AGGTGGAGCC GCTGCGCGCA GAGCTCCAAG541AGGGCGCGCG CCAGAAGCTG CACGAGCTGC AAGAGAAGCT GAGCCCACTG GGCGAGGAGA601TGCGCGACCG CGCGCGCGCC CATCTGGACG CGCTGCGCAC GCATCTGGCC CCCTACAGCG661ACGAGCTGCG CCAGCGCTTG GCCGCGCGCC TTGAGCCTCT CAAGGACAAC GGCGGCGCCA721GACTGGCCGA GTACCACGCC AAGGCCACCG AGCATCTGAG CACGCTCAGC GAGAAGGCCA781AGCCCGCGCT CGAGGACCTC CGCCAAGCCC TCCTGCCCGT GCTGGAGAGC TTCAAGGTCA841GCTTCCTGAG CGCTCTCGAC GACTACACTA AGAAGCTCAA CACCCAGTGA GCCGCCCGCC901GCCGCCCCCC TTCCCGGTGC TCAGAATAAA CGTTTCCAAA GTGGGAAAAA AAAAAAAAAG961AATTCGENBANK ID: XM_007441.1DEFINITION HOMO SAPIENS PRESENILIN 1 (ALZHEIS2ER DISEASE 3) (PSEN1),MRNA.VERSION XM_007441.1 GI:11435041CDS 249..1652/CODON_START=11TGGGACAGGC AGCTCCGGGG TCCGCGGTTT CACATCGGAA ACAAAACAGC GGCTGGTCTG61GAAGGAACCT GAGCTACGAG CCGCGGCGGC AGCGGGGCGG CGGGGAAGCG TATACCTAAT121CTGGGAGCCT GCAAGTGACA ACAGCCTTTG CGGTCCTTAG ACAGGTTGGG CTGGAGGAGA181ACACATGAAA GAAAGAACCT CAAGAGGCTT TGTTTTCTGT GAAACAGTAT TTCTATACAG241TTGCTCCAAT GACAGAGTTA CCTGCACCGT TGTCCTACTT CCAGAATGCA CAGATGTCTG301AGGACAACCA CCTGAGCAAT ACTGTACGTA GCCAGAATGA CAATAGAGAA CGGCAGGAGC361ACAACGACAG ACGGAGCCTT GGCCACCCTG AGCCATTATC TAATGGACGA GCGCAGGGTA421ACTCCCGGCA GGTGGTGGAG CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG481GCGCCAAGCA TGTGATCATG CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG541CTACCATTAA GTCAGTCAGC TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT601TCACAGAAGA TACCGAGACT GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA661TCATGATCAG TGTCATTGTT GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT721GCTATAAGGT CATCCATGCC TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT781CATTCATTTA CTTGGGGGAA GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG841TTGCACTCCT GATCTGGAAT TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC901CACTTCGACT CCAGCAGGCA TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA961TCAAGTACCT CCCTGAATGG ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT1021TAGTGGCTGT TTTGTGTCCG AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA1081GAAATGAAAC GCTTTTTCCA GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA1141TGGCAGAAGG AGACCCGGAA GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG1201AAAGCACAGA AAGGGAGTCA CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG1261AGGAATGGGA AGCCCAGAGG GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC1321GAGCTGCTGT CCAGGAACTT TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG1381GAGTAAAACT TGGATTGGGA GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG1441CAACAGCCAG TGGAGACTGG AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT1501TGTGCCTTAC ATTATTACTC CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT1561CCATCACCTT TGGGCTTGTT TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG1621ACCAATTAGC ATTCCATCAA TTTTATATCT AGCATATTTG CGGTTAGAAT CCCATGGATG1681TTTCTTCTTT GACTATAACA AAATCTGGGG AGGACAAAGG TGATTTTCCT GTGTCCACAT1741CTAACAAAGT CAAGATTCCC GGCTGGACTT TTGCAGCTTC CTTCCAAGTC TTCCTGACCA1801CCTTGCACTA TTGGACTTTG GAAGGAGGTG CCTATAGAAA ACGATTTTGA ACATACTTCA1861TCGCAGTGGA CTGTGTCCCT CGGTGCAGAA ACTACCAGAT TTGAGGGACG AGGTCAAGGA1921GATATGATAG GCCCGGAAGT TGCTGTGCCC CATCAGCAGC TTGACGCGTG GTCACAGGAC1981GATTTCACTG ACACTGCGAA CTCTCAGGAC TACCGTTACC AAGAGGTTAG GTGAAGTGGT2041TTAAACCAAA CGGAACTCTT CATCTTAAAC TACACGTTGA AAATCAACCC AATAATTCTG2101TATTAACTGA ATTCTGAACT TTTCAGGAGG TACTGTGAGC AAGAGCAGGC ACCAGCAGCA2161GAATGGGGAA TCGACAGGTG GGCAGCGGTT CCAGCTTCCC TTTGATTTTT TGCTGCAGAC2221TCATCCTTTT TAAATGAGAC TTGTTTTCCC CTCTCTTTGA GTCAAGTCAA ATATGTAGAT2281TGCCTTTGGC AATTCTTCTT CTCAAGCACT GACACTCATT ACCGTCTGTG ATTGCCATTT2341CTTCCCAAGG CCAGTCTGAA CCTGAGGTTG CTTTATCCTA AAAGTTTTAA CCTCAGGTTC2401CAAATTCAGT AAATTTTGGA AACAGTACAG CTATTTCTCA TCAATTCTCT ATCATGTTGA2461AGTCAAATTT GGATTTTCCA CCAAATTCTG AATTTCTAGA CATACTTGTA CGCTCACTTG2521CCCCAGATGC CTCCTCTGTC CTCATTCTTC TCTCCCACAC AAGCAGTCTT TTTCTACAGC2581CAGTAAGGCA GCTCTGTCGT GGTAGCAGAT GGTCCCATTA TTCTAGGGTC TTACTCTTTG2641TATGATGAAA AGAATGTGTT ATGAATCGGT GCTGTCAGCC CTGCTGTCAG ACCTTCTTCC2701ACAGCAAATG AGATGTATGC CCAAAGACGG TAGAATTAAA GAAGAGTAAA ATGGCTGTTG2761AAGCGENBANK ID: XM_087242.1DEFINITION HOMO SAPIENS ARGINYL AMINOPEPTIDASE (AMINOPEPTIDASE B) -LIKE1(RNPEPL1), MRNA.VERSION XM_087242.1 GI:18600482CDS 700..1764/CODON_START=11GTGGACCCGT TCACCGACTA CGGCTCCTCC CTCACCGTCA CGCTGCCGCC CGAGCTGCAG61GCGCACCAGC CCTTCCAGGT CATCCTGCGG TACACCTCGA CCGACGCCCC CGCCATCTGG121TGGCTGGACC CAGAGCTGAC CTATGGCTGC GCCAAGCCCT TCGTCTTCAC CCAGGGCCAC181TCCGTGTGCA ACCGCTCCTT CTTCCCGTGC TTCGACACAC CTGCCGTGAA GTGCACCTAC241TCTGCCGTCG TCAAGGCGCC ATCGGGGGTG CAGGTGCTGA TGAGTGCCAC CCGGAGTGCA301TACATGGAGG AAGAAGGCGT CTTCCACTTC CACATGGAGC ACCCCGTGCC CGCCTACCTC361GTGGCCCTGG TGGCCGGAGA CCTCAAGCCG GCAGACATCG GGCCCAGGAG CCGCGTGTGG421GCCGAGCCAT GCCTCCTGCC CACGGCCACC AGCAAGCTGT CGGGCGCAGT GGAGCAGTGG481CTGAGTGCAG CTGAGCGGCT GTATGGGCCC TACATGTGGG GCAGGTACGA CATTGTCTTC541CTGCCACCCT CCTTCCCCAT CGTGGCCATG GAGAACCCCT GCCTCACCTT CATCATCTCC601TCCATCCTGG AGAGCGATGA GTTCCTGGTC ATCGATGTCA TCCACGAGGT GGCCCACAGT661TGGTTCGGCA ACGCTGTCAC CAACGCCACG TGGGAAGAGA TGTGGCTGAG CGAGGGCCTG721GCCACCTATG CCCAGCGCCG TATCACCACC GAGACCTACG GTGCTGCCTT CACCTGCCTG781GAGACTGCCT TCCGCCTGGA CGCCCTGCAC CGGCAGATGA AGCTTCTGGG AGAGGACAGG841CCGGTCAGCA AACTGCAGGT CAAGCTGGAG CCAGGAGTGA ATCCCAGCCA CCTGATGAAC901CTGTTCACCT ACGAGAAGGG CTACTGCTTC GTGTACTACC TGTCCCAGCT CTGCGGAGAC961CCACAGCGCT TTGATGACTT TCTCCGAGCC TATGTGGAGA AGTACAAGTT CACCAGCGTG1021GTGGCCCAGG ACCTGCTGGA CTCCTTCCTG AGCTTCTTCC CGGAGCTGAA GGAGCAGAGC1081GTGGACTGCC GGGCAGGGCT GGAATTCGAG CGCTGGCTCA ATGCCACAGG CCCGCCGCTG1141GCTGAGCCGG ACCTGTCTCA GGGATCCAGC CTGACCCGGC CCGTGGAGGC CCTTTTCCAG1201CTGTGGACCG CAGAACCTCT GGACCAGGCA GCTGCCTCGG CCAGCGCCAT TGACATCTCC1261AAGTGGAGGA CCTTCCAGAC AGCACTCTTC CTGGACCGGC TCCTGGATGG GTCCCCGCTG1321CCGCAGGAGG TGGTGATGAG CCTGTCCAAG TGCTACTCCT CCCTGCTGGA CTCGATGAAC1381GCTGAGATCC GCATCCGCTG GCTGCAGATT GAGGTCCGCA ACGACTACTA TCCTGACCTC1441CACAGGGTGC GGCGCTTCCT GGAGAGCCAG ATGTCACGCA TGTACACCAT CCCGCTGTAC1501GAGGACCTCT GCACCGGTGC CCTCAAGTCC TTCGCGCTGG AGGTCTTCTA CCAGACGCAG1561GGCCGGCTGC ACCCCAACCT GCGCAGAGCC ATCCAGCAGA TCCTGTCCCA GGGCCTGGGC1621TCCAGCACAG AGCCCGCCTC AGAGCCCAGC ACGGAGCTGG GCAAGGCTGA AGCAGACACA1681GACTCGGACG CACAGGCCCT GCTGCTTGGG GACGAGGCCC CCAGCAGTGC CATCTCTCTC1741AGGGACGTCA ATGTGTCTGC CTAGCCCTGT TGGCGGGCTG ACCCTCGACC TCCCAGACAC1801CACAATTGTG CCTTCTGTGG GCCAGGCCTG CCATGACTGC GTCTCGGCTC TGGCCATGAG1861CTCTGCCCAG GCCCACAAGC CCCTCCCCTG GGCTCTCCCA GGCAGGGAGA ATGGGGAGAG1921GGACCTCCTT GTGTCTGGCA GAGACCTGTG GACCTGGCCT CCCCACTCCC AGCTCTCTTG1981CACTGCAGGC CCTGGGGCCA GCCCGCACAC ACCATGCCTC CTGTCTCAAC ACTGACAGCT2041GTGCCTAGCC CCGGATGCCA GCACCTGCCA GGTGCCGCCC CGGGGCAAGG GCCCCAGCAG2101CCCTATGGTG ACCGCCACAC TGTGCCTTAA TGTCTGCCGG GGGCCCAGGC TGTGCTGTCC2161CTGCAGCACG CCTCCTTGCA GGGATCTGAG CCACCCTCCC CGCACAGCCC TGCACCCCGC2221CCCTAGGGTT GGCAGCCTCA GTTGGCCCCT GGCAGAGGAA CAAGGACACA GACATTCCCT2281CAGTGTGGGG GGCAGGGGAC ACAGGGAGAG GATGGTTGTC CCTGGGGAGG GCCCTCTGGC2341CCCAGGCAAC CTTAGCCCCT CAGAACAGGG AGTCCCAGGA CCCAGGGAGA GTGTGGGGAC2401AGGACAGCCT GTCTCTTGTA GCTTCCTGGG GTGGGAGGCA CAGGGGCAAA GCAATACCCC2461AGGGAAAGTG GGAGGTGGTG CTGGTGCTCT CTCCAGGCCC ACCATGCTGG GAGAGGCGGC2521CAGAGCCTGG GGCCTCCAGC CTGGGACTGC TGTGATGGGG TATCACGGTG ATGGTCCCAT2581TAAACTTCCA CTCTGCAAAC CTGGENBANK ID: S90469DEFINITION CYTOCHROME P450 REDUCTASE [HUMAN, PLACENTA, MRNA PARTIAL, 2403NT].VERSION S90469.1 GI:247306CDS 1..2031CODO_START=11GGAGACTCCC ACGTGGACAC CAGCTCCACC GTGTCCGAGG CGGTCGCCGA AGAAGTATCT61CTTTTCAGCA TGACGCACAT GATTCTGTTT TCGCTCATCG TGGGTCTCCT AACCTACTGG121TTCCTCTTCA GAAAGAAAAA AGAAGAAGTC CCCGACTTCA CCAAAATTCA GACATTGACC181TCCTCTGTCA GAGAGAGGAG CTTTGTGGAA AAGATGAAGA AAACGGGGAG GAACATCATC241GTGTTCTACG GCTCCCAGAC GGGGACTGCA GAGGAGTTTG CCAACCGCCT GTCCAAGGAC301GCCCACCGCT ACGGGATGCG AGGCATGTCA GCGGACCCTG AGGAGTATGA GCTGCCGGAC361CTGAGCAGCC TGCCAGAGAT CGACAACGCC CTGGTGGTTT TCTGCATGGC CACGTACGCT421GAGGGAGACC CCACCGACAA TGCCCAGGAC TTCTACGACT GGCTGCAGGA GACAGACGTG481GATCTCTCTG GGGTCAAGTT CGCGGTGTTT GGTCTTGGGA ACAAGACCTA CGAGCACTTC541AATGCCATGG GCAAGTACGT GGACAAGCGG CTGGAGCAGC TCGGCGCCCA GCGCATCTTT601GAGCTGGGGT TGGGCGACGA CGATGGGAAC TTGGAGGAGG ACTTCATCAC CTGGCGAGAG661CAGTTCTGGC CGGCCGTGTG TGAACACTTT GGGGTGGAAG CCACTGGCGA GGAGTCCAGC721ATTCGCCAGT ACGAGCTTGT GGTCCACACC GACATAGATG CGGCCAAGGT GTACATGGGG781GAGATGGGCC GGCTGAAGAG CTACGAGAAC CAGAAGCCCC CCTTTGATGC CAAGAATCCG841TTCCTGGCTG CAGTCACCAC CAACCGGAAG CTGAACCAGG GAACCGAGCG CCACCTCATG901CACCTGGAAT TGGACATCTC GGACTCCAAA ATCAGGTATG AATCTGGGGA CCACGTGGCT961GTGTACCCAG CCAACGACTC TGCTCTCGTC AACCAGCTGG GCAAAATCCT GGGTGCCGAC1021CTGGACGTCG TCATGTCCCT GAACAACCTG GATGAGGAGT CCAACAAGAA GCACCCATTC1081CCGTGCCCTA CGTCCTACCG CACGGCCCTC ACCTACTACC TGGACATGAC CAACCCGCCG1141CGTACCAACG TGCTGTACGA GCTGGCGCAG TACGCCTCGG ACCGCTGGGA GCAGGAGCTG1201CTGCGCAAGA TGGCCTCCTC CTCCGGCGAG GGCAAGGAGC TGTACCTGAG CTGGGTGGTG1261GAGGGCGGGA GGCACATCCT GGCCATCCTG CAGGACTGCC CGTCCCTGCG GCCCCCCATC1321GACCACCTGT GTGAGCTGCT GCCGCGCCTG CAGGCCCGCT ACTACTCCAT CGCCTCATCC1381TCCAAGGTCC ACCCCAACTC TGTGCACATC TGTGCGGTGG TTGTGGAGTA CGAGACCAAG1441GCCGGCCGCA TCAACAAGGG CGTGGCCACC AACTGGCTGC GGGCCAAGGA GCCTGTCGGG1501GAGAACGGCG GCCGTGCGCT GGTGCCCATG TTCGTGCGCA AGTCCCAGTT ACGCCTGCCC1561TTCAAGGCCA CCACGCCTGT CATCATGGTG GGCCCCGGCA CCGGGTGGCA CCCTTTCATA1621GGCTTCATCC AGGAGCGGGC CTGGCTGCGA CAGCAGGGCA AGGAGGTGGG GGAGACGCTG1681CTGTACTACG GCTGCCGCCG CTCGGATGAG GACTACCTGT ACGGGGAGGA GCTGGCGCAG1741TTCCACAGGG ACGGTGCGCT CACCCAGCTC AACGTGGCCT TCTCCCGGGA GCAGTCCCAC1801AAGGTCTACG TCCAGCACCT GCTAAAGCAA GACCGAGAGC ACCTGTGGAA GTTGATCGAA1861GGCGGTGCCC ACATCTACGT CTGTGGGGAT GCACGGAACA TGGCCAGGGA TGTGCAGAAC1921ACCTTCTACG ACATCGTGGC TGAGCTCGGG GCCATGGAGC ACGCGCAGGC GGTGGACTAC1981ATCAAGAAAC TGATGACCAA GGGCCGCTAC TCCCTGGACG TGTGGAGCTA GGGGCCTGCC2041TGCCCCACCC ACCGCACAGA CTCCGGCCTG TAATCAGCTC TCCTGGCTCC CTCCCGTAGT2101CTCCTGGGTG TGTTTGGCTT GGCCTTGGCA TGGGCGCAGG CCCAGTGACA AAGACTCCTC2161TGGGCCTGGG GTGCATCCTC CTCAGCCCCC AGGCCAGGTG AGGTCCACCG GCCCCTGGCA2221GCACAGCCCA GGGCCTGCAT GGGGGCACCG GGCTCCATGC CTCTGGAGCC TCTGGCCCTC2281GGTGGCTGCA CAGAAGGGCT CTTTCTCTCT GCTGAGCTGG CCCAGCCCCT CCACGTGATT2341TCCAGTGAGT GTAAATAATT TTAAATAACC TCTGGCCCTT GGAATAAAGT TCTGTTTTCT2401GTAGENBANK ID: NM_006254.1DEFINITION HOMO SAPIENS PROTEIN KINASE C, DELTA (PRKCD), MRNA.VERSION NM_006254.1 GI:5453969CDS 59..2089/CODON_START=11TGCCGCCGCG ACCCTTGGCG CCTGCCCCTG CAACGGGAGC CCCACTGCAG GCCCCACCAT61GGCGCCGTTC CTGCGCATCG CCTTCAACTC CTATGAGCTG GGCTCCCTGC AGGCCGAGGA121CGAGGCGAAC CAGCCCTTCT GTGCCGTGAA GATGAAGGAG GCGCTCAGCA CAGAGCGTGG181GAAAACACTG GTGCAGAAGA AGCCGACCAT GTATCCTGAG TGGAAGTCGA CGTTCGATGC241CCACATCTAT GAGGGGCGCG TCATCCAGAT TGTGCTAATG CGGGCAGCAG AGGAGCCAGT301GTCTGAGGTG ACCGTGGGTG TGTCGGTGCT GGCCGAGCGC TGCAAGAAGA ACAATGGCAA361GGCTGAGTTC TGGCTGGACC TGCAGCCTCA GGCCAAGGTG TTGATGTCTG TTCAGTATTT421CCTGGAGGAC GTGGATTGCA AACAATCTAT GCGCAGTGAG GACGAGGCCA AGTTCCCAAC481GATGAACCGC CGCGGAGCCA TCAAACAGGC CAAAATCCAC TACATCAAGA ACCATGAGTT541TATCGCCACC TTCTTTGGGC AACCCACCTT CTGTTCTGTG TGCAAAGACT TTGTCTGGGG601CCTCAACAAG CAAGGCTACA AATGCAGGCA ATGTAACGCT GCCATCCACA AGAAATGCAT661CGACAAGATC ATCCGCAGAT CCACTGGCAC CGCCGCCAAC AGGCGGGACA CTATATTCCA721GAAAGAACGC TTCAACATCC ACATGCCGCA CCGCTTCAAG GTTCACAACT ACATGAGCCC781CACCTTCTGT GACCACTGCG GCAGCCTGCT CTGGGGACTG GTGAAGCAGG GATTAAAGTG841TGAAGACTGC GGCATGAATG TGCACCATAA ATGCCGGGAG AAGGTGGCCA ACCTCTGCGG901CATCAACCAG AAGCTTTTGG CTGAGGCCTT GAACCAAGTC ACGCAGAGAG CCTCCCGGAG961ATCAGACTCA GCCTCCTCAG AGCCTGTTGG GATATATCAG GGTTTCGAGA AGAAGACCGG1021AGTTGCTGGG GAGGACATGC AAGACAACAG TGGGACCTAC GGCAAGATCT GGGAGGGCAG1081CAGCAAGTGC AACATCAACA ACTTCATCTT CCACAAGGTC CTGGGCAAAG GCAGCTTCGG1141GAAGGTGCTG CTTGGAGAGC TGAAGGGCAG AGGAGACTAC TCTGCCATCA AGGCCCTCAA1201GAAGGATGTG GTCCTGATCG ACGACGACGT GGAGTGCACC ATGGTTGAGA AGCGGGTGCT1261GACACTTGCC GCAGAGAATC CCTTTCTCAC CCACCTCATC TGCACCTTCC AGACCAAGGA1321CCACCTGTTC TTTGTGATGG AGTTCCTCAA CGGGGGGGAC CTGATGTACC ACATCCAGGA1381CAAAGGCCGC TTTGAACTCT ACCGTGCCAC GTTTTATGCC GCTGAGATAA TGTGTGGACT1441GCAGTTTCTA CACAGCAAGG GCATCATTTA CAGGGACCTC AAACTGGACA ATGTGCTGTT1501GGACCGGGAT GGCCACATCA AGATTGCCGA CTTTGGGATG TGCAAAGAGA ACATATTCGG1561GGAGAGCCGG GCCAGCACCT TCTGCGGCAC CCCTGACTAT ATCGCCCCTG AGATCCTACA1621GGGCCTGAAG TACACATTCT CTGTGGACTG GTGGTCTTTC GGGGTCCTTC TGTACGAGAT1681GCTCATTGGC CAGTCCCCCT TCCATGGTGA TGATGAGGAT GAACTCTTCG AGTCCATCCG1741TGTGGACACG CCACATTATC CCCGCTGGAT CACCAAGGAG TCCAAGGACA TCCTGGAGAA1801GCTCTTTGAA AGGGAACCAA CCAAGAGGCT GGGAATGACG GGAAACATCA AAATCCACCC1861CTTCTTCAAG ACCATAAACT GGACTCTGCT GGAAAAGCGG AGGTTGGAGC CACCCTTCAG1921GCCCAAAGTG AAGTCACCCA GAGACTACAG TAACTTTGAC CAGGAGTTCC TGAACGAGAA1981GGCGCGCCTC TCCTACAGCG ACAAGAACCT CATCGACTCC ATGGACCAGT CTGCATTCGC2041TGGCTTCTCC TTTGTGAACC CCAAATTCGA GCACCTCCTG GAAGATTGAG GTTCCTGGAC2101AGATGENBANK ID: X61971.1DEFINITION H. SAPIENS MRNA FOR MACROPAIN SUBUNIT DELTA.VERSION X61971.1 GI:296733CDS <1..543/CODON_START=11ATCGCCAATC GAGTGACTGA CAAGCTGACA CCTATTCACG ACCGCATTTT CTGCTGTCGC61TCAGGCTCAG CTGCTGATAC CCAGGCAGTA GCTGATGCTG TCACCTACCA GCTCGGTTTC121CACAGCATTG AACTGAATGA GCCTCCACTG GTCCACACAG CAGCCAGCCT CTTTAAGGAG181ATGTGTTACC GATACCGGGA AGACCTGATG GCGGGAATCA TCATCGCAGG CTGGGACCCT241CAAGAAGGAG GGCAGGTCTA CTCAGTGCCT ATGGGGGGTA TGATGGTAAG GCAGTCCTTT301GCCATTGGAG GCTCCGGGAG CTCCTACATC TATGGCTATG TTGATGCTAC CTACCGGGAA361GGCATGACCA AGGAAGAGTG TCTGCAATTC ACGGCCAATG CTCTCGCTTT GGCCATGGAG421CGGGATGGCT CCAGTGGAGG AGTGATCCGC CTGGCAGCCA TTGCAGAGTC AGGGGTAGAG481CGGCAAGTAC TTTTGGGAGA CCAGATACCC AAATTCGCCG TTGCCACTTT ACCACCCGCC541TGAATCCTGG GATTCTAGTA TGCAATAAGA GATGCCCTGT ACTGATGCAA AATTTAATAA601AGTTTGTCAC AGAGAAAAAA AAAAGENBANK ID: AH005909.1GENBANK ID: XM_088424.1DEFINITION HOMO SAPIENS RETINOID X RECEPTOR, ALPHA (RXRA), MRNA.VERSION XM_088424.1 GI:18571706CDS 519..1016/CODON_START=11AAGCAGAACC TGGCCTCCCT GGCCACAGCA GCCTTACCCA CCGCTCTACG TGTCCCGGGC61ACTTCCCGCA GCCTTCCCGT CCCTTTCTCA TCGGCCTTGT AGTTGTACAG TGCTGTTGGT121TTGAAAAGGT GATGTGTGGG GAGTGCGGCT CATCACTGAG TAGAGAGGTA GAATTTCTAT181TTAACCAGAC CTGTAGTAGT ATTACCAATC CAGTTCAATT AAGGTGATTT TTTGTAATTA241TTATTATTTT GGTGGGACAA TCTTTAATTT TCTAAAGATA GCACTAACAT CAGCTCATTA301GCCACCTGTG CCTGTCCCCG CCTTGGCCCG GCTGGATGAA GCGGCTTCCC CGCAGGGCCC361CCACTTCCCA GTGGCTGCTT CCTGGGGACC CAGGGCACCC CGGCACCTTC AGGCACGCTC421CTCAGCTGGT CACCTCCCGG CTTTGCCGTT CAGATGGGGC TCCTGAGGCT CAGGAGTGAA481GATGCCACAG AGCCGGGCTC CCCTAGGCTG CGTCGGGCAT GCTTGGAAGC TGGCCTGCCA541GGACCTTCCA CCCTGGGGCC TGTGTCAGCC GCCGGCCCTC CGCACCCTGG AAGCACACGG601CCTCTGGGAA GGACAGCCCT GACCTTCGGT TTTCCGAGCA CGGTGTTTCC CAAGAATTCT661GGGCTTGCCG CCTGGTGGCA GTGCTGGAGA TGACCCCGAG CCCCTCCCCG TGGGGCACCC721AGGAGGGCCC TGCCGAAATG TGCAGCCTGT GGGTAGTCGG CTGGTGTCCC TGTCGTGGAG781CTGGGGTGCG TGATCTGGTG CTCGTCCACG CAGGTGTGTG GTGTAAACAT GTATGTGCTG841TACAGACAGA CGCGTGTGGA GAGAGCCGCA CACCAGCGCC ACCCAGGAAA GGCGGAGCGG901TTACCAGTGT TTTGTGTTTA TTTTTAATCA AGACGTTTCC CCTGTTTTCC TATAAATTTG961CTTCGTGTAA GCAAGTACAT AAGGACCCTC CTTTGGTGAA ATCCGGGTTC GAATGAATAT1021CTCAAGGCAG GAGATGCATC TATTTTAAGA TGCTTTGGAG CAGACAGCTT TAGCCGTTCC1081CAATCCTTAG CAATGCCTTA GCTGGGACGC ATAGCTAATA CTTTAGAGAG GATGACAGAT1141CCATAAAGAG AGTAAAGATA AGAGAAAATG TCTAAAGCAT CTGGAAAGGT AAAAAAAAAA1201AATCTATTTT TGTACAAATG TAATTTTATC CCTCATGTAT ACTTGGATAT GGCGGGGGGA1261GGGGTCGGAC TGTTTCGTTT CTGCTTCTAG AGATTGAGGT GAAAGCTTCG TCCGAGAAAC1321GCCAGGACAG ACGATGGCAG AGGAGAGGGC TCCTGTGACG GGGGCCAGGG TTGGGAGGAA1381ACCGCCGCAA TGGGGGTGTC TTCCCTCGGG GGAGGAGGGT GGGCCTGAGG CTTTCAAGGG1441TTTTCTTCCC TTTCGAGTAA TTTTTAAAGC CTTGCTCTGT TGTGTCCTGT TGCCGGCTCT1501GGCCTTCCTG TGACTGACTG TGAAGTGGCT TCTCCGTACG ATTGTCTCTG AAACATCGTG1561GCCGCAGGTG CCAGGGTTTG ATGGACAGTA GCATTAGAAT TGTGGAAAAG GAACACGCAA1621AGGGAGAAGT GTGAGAGGAG AAACAAAATA TGAGCGTTTA AAATACATCG CCATTCAGGENBANK ID: U41745.1DEFINITION HUMAN PDGF ASSOCIATED PROTEIN MRNA, COMPLETE CDS.VERSION U41745.1 GI:1136583CDS 22..567/CODON_START=11GAATTCCGCG GCGGCGCCTC AATGCCTAAA GGAGGAAGAA AGGGAGGCCA CAAAGGCCGG61GCGAGGCAGT ATACAAGCCC TGAGGAGATC GACGCGCAGC TGCAGGCTGA GAAGCAGAAG121GCCAGGGAAG AAGAGGAGCA AAAAGAAGGT GGAGATGGGG CTGCAGGTGA CCCCAAAAAG181GAGAAGAAAT CTCTAGACTC AGATGAGAGT GAGGATGAAG AAGATGACTA CCAGCAAAAG241CGCAAAGGCG TTGAAGGGCT CATCGACATC GAGAACCCCA ACCGGGTGGC ACAGACAACC301AAAAAGGTCA CACAACTGGA TCTGGACGGG CCAAAGGAGC TTTCGAGGAG AGAACGAGAA361GAGATTGAGA AGCAGAAGGC AAAAGAGCGT TACATGAAAA TGCACTTGGC CGGGAAGACA421GAGCAAGCCA AGGCTGACCT GGCCCGGCTG GCCATCATCC GGAAACAGCG GGAGGAGGCT481GCCCGGAAGA AGGAAGAGGA AAGGAAAGCA AAAGACGATG CCACATTGTC AGGAAAACGA541ATGCAGTCAC TCTCCCTGAA TAAGTAACTG CGACCCGTGG GAGGAGATGC CGGGGACCTG601GGCCGCGCTG CCAGGACCTC TGCTGTGTCT CGCCCACCCT GTGCCCTGGC GCCGCTGCAA661CAGCCCCTCA TGGCCAGGAG CCCCCCATGC CTGGGCCTCC TCTTCATCTT GGCACAGAAA721TTGTTTGGGG GATGGGGGGG GGACTGGGGG AGGGGTAGCT GCTATCTTTG AGACAGAAAG781ATGCAGGACA GCATTTCATA TGTAACCATT TGAATGTTTT TGCTGTTTTT AGAATTCGENBANK ID: AH002617.1GENBANK ID: XM_034862.1DEFINITION HOMO SAPIENS INTERFERON REGULATORY FACTOR 1 (IRF1), MRNA.VERSION XM_034862.1 GI:14726087CDS 197..1174/CODON_START=11CGAGCCCCGC CGAACCGAGG CCACCCGGAG CCGTGCCCAG TCCACGCCGG CCGTGCCCGG61CGGCCTTAAG AACCCGGCAA CCTCTGCCTT CTTCCCTCTT CCACTCGGAG TCGCGCTCCG121CGCGCCCTCA CTGCAGCCCC TGCGTCGCCG GGACCCTCGC GCGCGACCGC CGAATCGCTC181CTGCAGCAGA GCCAACATGC CCATCACTCG GATGCGCATG AGACCCTGGC TAGAGATGCA241GATTAATTCC AACCAAATCC CGGGGCTCAT CTGGATTAAT AAAGAGGAGA TGATCTTCCA301GATCCCATGG AAGCATGCTG CCAAGCATGG CTGGGACATC AACAAGGATG CCTGTTTGTT361CCGGAGCTGG GCCATTCACA CAGGCCGATA CAAAGCAGGG GAAAAGGAGC CAGATCCCAA421GACGTGGAAG GCCAACTTTC GCTGTGCCAT GAACTCCCTG CCAGATATCG AGGAGGTGAA481AGACCAGAGC AGGAACAAGG GCAGCTCAGC TGTGCGAGTG TACCGGATGC TTCCACCTCT541CACCAAGAAC CAGAGAAAAG AAAGAAAGTC GAAGTCCAGC CGAGATGCTA AGAGCAAGGC601CAAGAGGAAG TCATGTGGGG ATTCCAGCCC TGATACCTTC TCTGATGGAC TCAGCAGCTC661CACTCTGCCT GATGACCACA GCAGCTACAC AGTTCCAGGC TACATGCAGG ACTTGGAGGT721GGAGCAGGCC CTGACTCCAG CACTGTCGCC ATGTGCTGTC AGCAGCACTC TCCCCGACTG781GCACATCCCA GTGGAAGTTG TGCCGGACAG CACCAGTGAT CTGTACAACT TCCAGGTGTC841ACCCATGCCC TCCACCTCTG AAGCTACAAC AGATGAGGAT GAGGAAGGGA AATTACCTGA901GGACATCATG AAGCTCTTGG AGCAGTCGGA GTGGCAGCCA ACAAACGTGG ATGGGAAGGG961GTACCTACTC AATGAACCTG GAGTCCAGCC CACCTCTGTC TATGGAGACT TTAGCTGTAA1021GGAGGAGCCA GAAATTGACA GCCCAGGGGG GGATATTGGG CTGAGTCTAC AGCGTGTCTT1081CACAGATCTG AAGAACATGG ATGCCACCTG GCTGGACAGC CTGCTGACCC CAGTCCGGTT1141GCCCTCCATC CAGGCCATTC CCTGTGCACC GTAGCAGGGC CCCTGGGCCC CTCTTATTCC1201TCTAGGCAAG CAGCACCTGG CATCATGGTG GATATCGTGC ACAGAAGCTG GACTTCTCTG1261GGCCCCTCAA CAGCCAAGTG TGACCCCACT CCCAAGTGGG GATGGGGCCT CCCTCCTTGG1321GTCATTGACC TCTCAGGGCC TGGCAGGCCA GTGTCTGCGT TTTTCTTGTC GTCTAAAGCT1381GGCCCTGCCT CCTGGCAAGA TGAGGTTCTG AGACCAGTGT ATCAGGTCAG GCACTTGGAC1441AGGAGTCAGT GTCTGGCTTT TTCCTCTGAG CCCAGCTGCC TGGAGAGGGT CTCGCTGTCA1501CTGGGTGGCT CCTAGGGGAA CAGACCAGTG ACCCCAGAAA AGCATAACAC CAATCCCAGG1561GCTGGCTCTG CACTAAGAGA AAATTGCACT AAATCAATCT CGTTCCCAAA GAACTACCCC1621CTTTTCAGCT CAGCCCTGGG GACTGTTCCA AAGCCAGTGA AATGTGAAGG AAAGTGCGGT1681CCTTCGGGGC GATGCTGGCT CAGCCTCAGA GGAGCTCTAC CCTGCTCCCT GCTTTGGCTG1741AGGGGCTTGG GAAAAAAACT TGGCACTTTT TCGTGTGGAT CTTGCCACAT TTCTGATCAG1801AGGTGTACAC TAACATTTCC CCCGAGCTCT TGGCCTTTCC ATTTATTTAT ACAGTGCCTT1861GCTCGGCGCC CACCACCCCC TCAAGCCCCA GCAGCCCTCA ACAGGGCCAG GGAGGGAAGT1921GTGAGCGCCT TGGTATGACT TAAAATTGGA AATGTCATCT AACCATTAAG TCATGTGTGA1981ACACATAGGA CGTGTGTATA TATGTACATT TGTCTTTTTA TAAAAAGTAA ATTGTTGENBANK ID: AJ310549.1DEFINITION HOMO SAPIENS MRNA FOR CLP-36 PROTEIN.VERSION AJ310549.1 GI:13160404CDS 1..990/CODON_START=11ATGACCACCC ACCAGATAGA CCTCCAGGGC CCGGGGCCGT GGGGCTTCCG CCTCGTGGGC61GGCAAGGACT TCGAGCAGCC TCTCGCCATT TCCCGGGTCA CTCCTGGAAG CAAGGCGGCT121CTAGCTAATT TATGTATTGG AGATGTAATC ACAGCCATTG ATGGGGAAAA TACTAGCAAT181ATGACACACT TGGAAGCTCA GAACAGAATC AAAGGCTGCA CAGACAACTT GACTCTCACT241GTAGCCAGAT CTGAACATAA ACTGTGGTCT CCTCTGGTGA CGGAGGAAGG GAAGCGTCAT301CCATACAAGA TGAATTTAGC CTCTGAACCC CAGGAGGTCC TGCACATAGG AAGCGCCCAC361AACCGAAGTG CCATGCCCTT TACCGCCTCG CCTGCCTCCA GCACTACTGC CAGGGTCATC421ACAAACCAGT ACAACAACCC AGCTGGCCTC TACTCTTCTG AAAATATCTC CAACTTCAAC481AATGCCCTGG AGTCAAAGAC TGCTGCCAGC GGGGTGGAGG CGAACAGCAG ACCCTTAGAC541CATGCTCAGC CTCCAAGCAG CCTTGTCATC GACAAAGAAT CTGAAGTTTA CAAGATGCTT601CAGGAGAAAC AGGAGTTGAA TGAGCCCCCG AAACAGTCCA CGTCTTTCTT GGTTTTGCAG661GAAATCCTGG AGTCTGAAGA AAAAGGGGAT CCCAACAAGC CCTCAGGATT CAGAAGTGTT721AAAGCTCCTG TCACTAAAGT GGCTGCGTCG ATTGGAAATG CTCAGAAGTT GCCTATGTGT781GACAAATGTG GCACTGGGAT TGTTGGTGTG TTTGTGAAGC TGCGGGACCG TCACCGCCAC841CCTGAGTGTT ATGTGTGCAC TGACTGTGGC ACCAACCTGA AACAGAAGGG CCATTTCTTT901GTGGAGGATC AAATCTACTG TGAGAAGCAT GCCCGGGAGC GAGTCACACC ACCTGAGGGT961TATGAAGTGG TCACTGTGTT CCCCAAGTGA GCCAGCAGAT CTGACCACTG TTCTCCAGCA1021GGCCTCTGCT GCAGCTTTTT CTCTCAGTGT TCTGGCCCTC TCCTCTCTTG AAAGTTCTCT1081GCTTACTTTG GTTGENBANK ID: XM_016642.3DEFINITION HOMO SAPIENS ADENYLATE KINASE 3 (AK3), MRNA.VERSION XM_016642.3 GI:16163712CDS 145..816/CODON_START=11CCTTCCCCCT GTAGGGCCGG CCGGCGAGTC CCAGTGAGAG CGGAGGGTGC CAGAGGTAGG61GGGCCGAGAA ACAAAGTTCC CGGGGCTCCC TCCGGGGCCG CGGTCGGGGC TGCGCGTTTG121ACCGCCCCCC TCCTCGCGAA GGCAATGGCT TCCAAACTCC TGCGCGCGGT CATCCTCGGG181CCGCCCGGCT CGGGCAAGGG CACCGTGTGC CAGAGGATCG CCCAGAACTT TGGTCTCCAG241CATCTCTCCA GCGGCCACTT CTTGCGGGAG AACATCAAGG CCAGCACCGA AGTTGGTGAG301GTGGCAAAGC AGTATATAGA GAAAAGTCTT TTGGTTCCAG ACCATGTGAT CACACGCCTA361ATGATGTCCG AGTTGGAGAA TAGGCGTGGC CAGCACTGGC TCCTTGATGG TTTTCCTAGG421ACATTAGGAC AAGCCGAGGC CCTGGACAAA ATCTGTGAAG TGGATCTAGT GATCAGTTTG481AATATTCCAT TTGAAACACT TAAAGATCGT CTCAGCCGCC GTTGGATTCA CCCTCCTAGC541GGAAGGGTAT ATAACCTGGA CTTCAATCCA CCTCATGTAC ATGGTATTGA TGACGTCACT601GGTGAACCAT TAGTCCAGCA GGAGGAIGAT AAACCCGAAG CAGTTGCTGC CAGGCTAAGA661CAGTACAAAG ACGCGGCAAA GCCAGTCATT GAATTATACA AGAGCCGAGG AGTGCTCCAC721CAATTTTCCG GAACGGAGAC GAACAAAATC TGGCCCTACG TTTACACACT TTTCTCAAAC781AAGATCACAC CTATTCAGTC CAAAGAAGCA TATTGACCCT GCCCAATGGA AGAACCAGGA841AGATGTGGTC ATTCATTCAA TAGTGTGTGT AGTATTGGTG CTGTGTCCAA ATTAGAAGCT901AGCTGAGGTA GCTTGCAGCA TCTTTTCTAG TTGAAATGGT GAACTGATAG CAAAACAAAT961GAGTAGAAAG AGTTCATGAA GAGGCCCTCC TCTGCCTTTC AAAAGGGTGG TCACCTACAC1021ATGTTTAAGG TGTCTCTGCA CATGTCTCAA GCCCATCACA AGAAAGCAAG TACAGTGTGG1081ATTTCAAATG GTGTGTAACT TCAGCTCCAG CTGGTTTTTG ACAGCTGTTG CTGTGGTAAT1141ATTTTTTACA TGTGATGGTG ATAGTCTCTG GTTCTCCCCA TCCCCACAAA GGCTGTTGAA1201CCACACCACC AGGAAGCCTG AGAATGAATC CTGAGGGCTC TACCGCAGGC TTTGTCCCAG1261GCTTTCTGGT GTGTGCCCTC CTGGTAACAG TGAAATTGAA GCTACTTACT CATAGTGGTT1321GTTTCTCTGG TCTTGAGTGA CTGTGTCCAC AGTTCATTTT TTTCCGGTAG GAATAACTCC1381TTTTCTACAT CCACACTCCA TAGAGTCTCT CCTTTTCAGA TATCCTGGGA TGAAAGAATT1441TGGCTTTTTT TTTTTTTTTT TTTTTGACAT CTGTTTTCAC TCTTAGGCTT TTAAACAATA1501GTTATTGCTC TTATCCCTCT CAGATTCTAA TAACTGAGAG TGATGGGGCT ATATTGAATC1561TCTGTATGCA CTGAGAACTG AGCTATGAAG AGGATCTTAT TAAACTGCTG GTCTGACTTT1621ATGGATTGAC ACTGTTCCTT TCTTTTATTG TGGENBANK ID: Z35307.1DEFINITION H. SAPIENS MRNA FOR ENDOTHELIN-CONVERTING-ENZYME 1.VERSION Z35307.1 GI:535181CDS 38..2299/CODON_START=11CGCCCCCCCG GTGTCCGCCC TGCTGTCGGC GCTGGGGATG TCGACGTACA AGCGGGCCAC61GCTGGACGAG GAGGACCTGG TGGACTCGCT CTCCGAGGGC GACGCATACC CCAACGGCCT121GCAGGTGAAC TTCCACAGCC CCCGGAGTGG CCAGAGGTGC TGGGCTGCAC GGACCCAGGT181GGAGAAGCGG CTGGTGGTGT TGGTGGTACT TCTGGCGGCA GGACTGGTGG CCTGCTTGGC241AGCACTGGGC ATCCAGTACC AGACAAGATC CCCCTCTGTG TGCCTGAGCG AAGCTTGTGT301CTCAGTGACC AGCTCCATCT TGAGCTCCAT GGACCGCACA GTGGACCCCT GCCATGACTT361CTTCAGCTAC GCCTGTGGGG GCTGGATCAA GGCCAACCCA GTCCCTGATG GCCACTCACG421CTGGGGGACC TTCAGCAACC TCTGGGAACA CAACCAAGCA ATCATCAAGC ACCTCCTCGA481AAACTCCACG GCCAGCGTGA GCGAGGCAGA GAGAAAGGCG CAAGTATACT ACCGTGCGTG541CATGAACGAG ACCAGGATCG AGGAGCTCAG GGCCAAACCT CTAATGGAGT TGATTGAGAG601GCTCGGGGGC TGGAACATCA CAGGTCCCTG GGCCAAGGAC AACTTCCAGG ACACCCTGCA661GGTGGTCACC GCCCACTACC GCACCTCACC CTTCTTCTCT GTCTATGTCA GTGCCGATTC721CAAGAACTCC AACAGCAACG TGATCCAGGT GGACCAGTCT GGCCTGGGCT TGCGCTGGAG781AGACTATTAC CTGAACAAAA CTGAAAACGA GAAGGTGCTG ACCGGATATC TGAACTACAT841GGTCCAGCTG GGGAAGCTGC TGGGCGGCGG GGACGAGGAG GCCATCCGGC GCCAGATGCA901GCAGATCTTG GACTTTGAGA CGGCACTGGC CAACATCACC ATCCCACAGG AGAAGCGCCG961TGATGAGGAG CTCATCTACC ACAAAGTGAC GGCAGCCGAG CTGCAGACCT TGGCACCCGC1021CATCAACTGG TTGCCTTTTC TCAACACCAT CTTCTACCCC GTGGAGATCA ATGAATCCGA1081GCCTATTGTG GTCTATGACA AGGAATACCT TGAGCAGATC TCCACTCTCA TCAACACCAC1141CGACAGATGC CTGCTCAACA ACTACATGAT CTGGAACCTG GTGCGGAAAA CAAGCTCCTT1201CCTTGACCAG CGCTTTCAGG ACGCCGATGA GAAGTTCATG GAAGTCATGT ACGGGACCAA1261GAAGACCTGT CTTCCTCGCT GGAAGTTTTG CGTGAGTGAC ACAGAAAACA ACCTGGGCTT1321TGCGTTGGGC CCCATGTTTG TCAAAGCAAC CTTCGCCGAG GACAGCAAGA GCATAGCCAC1381CGAGATCATC CTGGAGATTA AGAAGGCATT TGAGGAAAGC CTGAGCACCC TGAAGTGGAT1441GGATGAGGAA ACCCGAAAAT CAGCCAAGGA AAAGGCCGAT GCCATCTACA ACATGATAGG1501ATACCCCAAC TTCATCATGG ATCCCAAGGA GCTGGACAAA GTGTTTAATG ACTACACTGC1561AGTTCCAGAC CTCTACTTTG AAAATGCCAT GCGGTTTTTC AACTTCTCAT GGAGGGTCAC1621TGCCGATCAG CTCAGGAAAG CCCCCAACAG AGATCAGTGG AGCATGACCC CGCCCATGGT1681GAACGCCTAC TACTCGCCCA CCAAGAATGA GATTGTGTTT CCGGCCGGGA TCCTGCAGGC1741ACCATTCTAC ACACGCTCCT CACCCAAGGC CTTAAACTTT GGTGGCATAG GTGTCGTCGT1801GGGCCATGAG CTGACTCATG CTTTTGATGA TCAAGGACGG GAGTATGACA AGGACGGGAA1861CCTCCGGCCA TGGTGGAAGA ACTCATCCGT GGAGGCCTTC AAGCGTCAGA CCGAGTGCAT1921GGTAGAGCAG TACAGCAACT ACAGCGTGAA CGGGGAGCCG GTGAACGGGC GGCACACCCT1981GGGGGAGAAC ATCGCCGACA ACGGGGGTCT CAAGGCGGCC TATCGGGCTT ACCAGAACTG2041GGTGAAGAAG AACGGGGCTG AGCACTCGCT CCCCACCCTG GGCCTCACCA ATAACCAGCT2101CTTCTTCCTG GGCTTTGCAC AGGTCTGGTG CTCCGTCCGC ACACCTGAGA GCTCCCACGA2161AGGCCTCATC ACCGATCCCC ACAGCCCCTC TCGCTTCCGG GTCATCGGCT CCCTCTCCAA2221TTCCAAGGAG TTCTCAGAAC ACTTCCGCTG CCCACCTGGC TCACCCATGA ACCCGCCTCA2281CAAGTGCGAA GTCTGGTAAG GACGAAGCGG AGAGAGCCAA GACGGAGGAG GGGAAGGGGC2341TGAGGACGAG ACCCCCATCC AGCCTCCAGG GCATTGCTCA GCCCGCTTGG CCACCCGGGG2401CCCTGCTTCC TCACACTGGC GGGTTTTCAG CCGGAACCGA GCCCATGGTG TTGGCTCTCA2461ACGTGACCCG CAGTCTGATC CCCTGTGAAG AGCCGGACAT CCCAGGCACA CGTGTGCGCC2521ACCTTCAGCA GGCATTCGGG TGCTGGGCTG GTGGCTCATC AGGCCTGGGC CCCACACTGA2581CAAGCGCCAG ATACGCCACA AATACCACTG TGTCAAATGC TTTCAAGATA TATTTTTGGG2641GAAACTATTT TTTAAACACT GTGGAATACA CTGGAAATCT TCAGGGAAAA ACACATTTAA2701ACACTTTTTT TTTTAAGCCCGENBANK ID: J02683DEFINITION HUMAN ADPATP CARRIER PROTEIN MRNA, COMPLETE CDS.VERSION J02683.1 GI:179246CDS 70..966/CODON_START=11CCGCAGCGCC GTAGTCAAAC CGAACCCGGC CCAGTCCCGT CCTGCAGCAG TCTGCCTCCT61TCTTTCAACA TGACAGATGC CGCATTGTCC TTCGCCAAGG ACTTCCTGGC AGGTGGAGTG121GCCGCAGCCA TCTCCAAGAC GGCGGTAGCG CCCATCGAGC CGGTCAAGCT GCTGCTGCAG181GTGCAGCATG CCAGCAAGCA GATCACTGCA GATAAGCAAT ACAAAGGCAT TATAGACTGC241GTGGTCCGTA TTCCCAAGGA GCACCAAGTT CTGTCCTTCT GGCGCGGTAA CCTGGCCAAT301GTCATCAGAT ACTTCCCCAC CCACGCTCTT AACTTCGCCT TCAAAGATAA ATACAAGCAG361ATCTTCCTCG GTGGTGTGGA CAAGAGAACC CAGTTTTGGC GCTACTTTGC AGGGAATCTG421GCATCGGGTG CTGCCGCAGG GGCCACATGC CTGTGTTTTC TGTACCCTCT TGATTTTGCC481CGTACCCGTC TAGCAGCTGA TGTGGGTAAA GCTGGAGCTG AAAGGGAATT CCGAGGCCTC541GGTGACTGCC TGGTTAAGAT CTACAAATCT GATGGGATTA AGGGCCTGTA CCAAGGCTTT601AACGTGTCTG TGCAGGGTAT TATCATCTAC CGAGCCGCCT ACTTCGGTAT CTATGACACT661GCAAAGGGAA TGCTTCCGGA TCCCAAGAAC ACTCACATCG TCATCAGCTG GATGATCGCA721CAGACTGTCA CTGCTGTTGC CGGGTTGACT TCCTATCCAT TTGACACCGT TCGCCGCCGC781ATGATGATGC AGTCAGGGCG CAAAGGAACT GACATCATGT ACACAGGCAC GCTTGACTGC841TGGCGGAAGA TTGCTCGTGA TGAAGGAGGC AAAGCTTTTT TCAAGGGTGC ATGGTCCAAT901GTTCTCAGAG GCATGGGTGG TGCTTTTGTG CTTGTCTTGT ATGATGAAAT CAAGAAGTAC961ACATAAGTTA TTTCCTAGGA TTTTTCCCCC TGTGAACAGG CATGTTGTAT TCTATAACAC1021AATCTTGAGC ATTGTTGACA GACTCCTGGC TGTCAGTTTC TCAGTGGCAA CTACTTTACT1081GGTTGAAAAT GGGAAGCAAT AATATTCATC TGACCAGTTT TCTCTTAAAG CCATTTCCAT1141GCATGATGAT GATGGGACTC AATTGTATTT TTTATTTCAG TCACTCCTGA CTAAATAACA1201ATTTGGAGAA ATAAAAATAG TCTAAAATGENBANK ID: M22760.1DEFINITION HOMO SAPIENS NUCLEAR-ENCODED MITOCHONDRIAL CYTOCHROME C OXI-DASE VASUBUNIT MRNA, COMPLETE CDS.VERSION M22760.1 GI:69535920..472/CODON_START=11GGGCGCCGCC ATCGCCGTCA TGCTGGGCGC CGCTCTCCGC CGCTGCGCTG TGGCCGCAAC61CACCCGGGCC GACCCTCGAG GCCTCCTGCA CTCCGCCCGG ACCCCCGGCC CCGCCGTGGC121TATCCAGTCA GTTCGCTGCT ATTCCCATGG GTCACAGGAG ACAGATGAGG AGTTTGATGC181TCGCTGGGTA ACATACTTCA ACAAGCCAGA TATAGATGCC TGGGAATTGC GTAAAGGGAT241AAACACACTT GTTACCTATG ATATGGTTCC AGAGCCCAAA ATCATTGATG CTGCTTTGCG301GGCATGCAGA CGGTTAAATG ATTTTGCTAG TCTAGTTCGA ATCCTAGAGG TTGTTAAGGA361CAAAGCAGGA CCTCATAAGG AAATCTACCC CTATGTCATC CAGGAACTTA GACCAACTTT421AAATGAACTG GGAATCTCCA CTCCGGAGGA ACTGGGCCTT GACAAAGTGT AAACCGCATG481GATGGGCTTC CCCAAGGATT TATTGACATT GCTACTTGAG TGTGAACAGT TACCTGGAAA541TACTGATGAT AACATATTAC CTTATTTTGA ACAAGTTTCC CTTTATTGAG TACCAAGCCA601TGTAATGGTA ACTTGGACTT TAATAAAAGG GAAATGAGTT TGAACTGGENBANK ID: 5118079DNA LINEARDEFINITION HUMAN, INTESTINAL FATTY ACID BINDING PROTEIN GENE, COMPLETECDS, AND AN ALU REPETITIVE ELEMENT.VERSION M18079.1 GI:1823511GTAATATCTT GGGCAAGCCC TAGAGCTTCT TTCCTGACCC TTAGTTAATA AGATGTTATC61TGGTCACATT CAGTCACAAT AATAGACTCA TTTTAGTAAT AAACATCTTA AGACTAGTAA121TTAAAACTCT TTACTTCACA CCAAGTTTCC TCCCCAAGCT TGGCCTGTTC CTGGCTGGCA181GCCTGAAGTA GGGAAAGGAG AGATATGGTG ACCTTTTCTT TGTACCTTTC TAGCTACCCT241CTATACCCTG ACCCCACATA CATAATTGAG CTGTGGCTTC TGACTCTACT GGGTTTGGGG301ATGAGAGGCA GTGAGAGTAA AATGAAGGAG TGGTTTTAAT TAATGGCACA GCTAAAACTG361GATTTTGTTC TCTCTGCACA TGGCAGATGT TTAAAGCTCA TTCTTTCTTT TATGCAAGTT421TTTACACCAT CCAGCCTCAT TTGTACCTCT TGAATTTTTG CTCAGTGGCC TATCACCATT481CAGGATCAAG ACAAAAATCA ATGAGCACTT ATTGTGTGTC ATGCACCCTA CAAAGTGCCA541GGATATTTAT CCAAACTCCT GGCAATGCTA AACACAATGC AAAAAGACAT ATTAGAAAAC601GAATCTTATT AACTTTAGCT TTTCAACTGT ATTTCATCAT AAAGTCTTAC TTTACAAGAT661AATTGCTGTT GTGAAAAAGG GAAAGGTCAT GGTCTCATTT CCCAGATGTT ATTTGATATA721TGCTATAAAT TATATTACCT CCAACATAGT CTGCACTTTG AACTTAGAAA AACAATCTTC781AGACGGCATG CATTCTAATT CTTGAAATAA GTATGCCCAC AAACTGTAGT TTAAGACAGA841ATAGGTATGC TTCTCATGTT TTAATTCAGT TGAATTTCAG AAGATCTCAG GAATGTACAG901AACGAGAATT AAGAATTAAT AAGAATAAGA ATTAATTAAT TGCTTGACAT AGAGTAGTTA961GGTGATTTCC TGAACTTTAA GCTTCCACAT CACACTATGA AGTTGGTTCA AGATAAGAAA1021TATAATAAAT TCTCGCCCAA GGACAGACCT GAATCTCTAG CTGCCTAGAG GCTGACTCAA1081CTGAAATCAT GGCGTTTGAC AGCACTTCCA AGGTAGACCG GAGTGAAAAC TATGACAAGT1141TCATGGAAAA AATGGGTAAA GACTTTATTT CTTTGTGCCT CATTCTTTGC TTTCTTACAA1201ACATTTTTCT TTCTAACTCC TAAATCTCTA GGAGATTACA GATAGCTTAC AGATAGCTCC1261TGATGTGGTA GAGACGGATC CAGAAGATGT TCAGAGGAGG GAAACCATAT TTTCCCTTCT1321TACATTAGGA AGAATCCACT ATCTCACTAA TGCAAGAAAA GATTCTTTGA GTGCTGTTCT1381CTGAAACACA CCAAAAAGAT CCAGAAATGT TTCCTTCACT CTTTAACTGA AAAATGACTT1441TTTTTCTTGT TTACAGTAAG AAAATGGCAG CGTGTAATGA TAACTTCCAG ATCTGAAAAT1501GTTAAATTCT ACGAGATGGA AAAACAAAGA CCATATAACA AAGTAATGGA AAAAGTTCTC1561TTAAAATTTA TAGCTCTGAA TAAGTTAGAT TTAATTCTGA TTTCTTCTAA CTTAAAAAAG1621TTTTGGAATA ATCTTGAGAA GCTGTGTAGT TTTCTCCAGG GCGTTTAATT TAACTGATTT1681ATAATTTGAT ACCAATACTC TGGCAGCCCA TATACTATAC AAGATAGGCA AACAAATTTG1741TGTCATTCCC CTAAAAGAAA AATCTGCATC AATTATAGCT TACAGTTTAG GAACTCTAAG1801TTTAAATTTA TAAAAGTTGT AGATTCTTAT AGTGATTTTG GCTTAATATT TGCTAATTTT1861CTCATTTTTG TGTCAGAAAG AAATGCCACA AGAAGCAAAT AGAACTATAA AGTTCAAAAT1921GTTAAAGCCA CTAAGAAAAA CAAAGGGGCA TTTAAGAAAA AAGAATACTG TATATGTGGA1981ATTAAAGATG TGCTTCCTTA TAAATATATG AATATACATT TTAATCCTTC ATTTAATATT2041TCTAGAATTT GATTTACTTA ACACTGAAAT GAACAGTTTG TTAATCTTAT TAAGGTTGCT2101CAGCTCTAAG ATTCTATAAT TCTGTACTCT ACTTAATTTT TCTCAAGTTA TGGAAAAACA2161ACTTTAATCA GTTCTCTTGA TCGGATTGAA CCTGAACTTC TATAGAAGCA ATCTGAATGT2221TCTTGTGCAA AGGCAATGCT ACCGAGTTTT CTTCCCACCC TCAAAATAAA CAAACAAAAC2281ATAACTTGGA AAAATAAACA CTTCCTATGG GATTTGACTT TATTTTCTCC ATTGTCTTAC2341CTTTTACAGG TGTTAATATA GTGAAAAGGA AGCTTGCAGC TCATGACAAT TTGAAGCTGA2401CAATTACACA AGAAGGAAAT AAATTCACAG TCAAAGAATC AAGCGCTTTT CGAAACATTG2461AAGTTGTTTT TGAACTTGGT GTCACCTTTA ATTACAACCT AGCAGACGGA ACTGAACTCA2521GGGTAAGAAT TTTTTTTTTT ATGAGCAATG CATTCTTGAT TTTTCTACCC AATATTAAAA2581TGATTTCTGC TCTATTTCAT TGGATGGTTT AATTAATGCA GGTCTCCTTC ACTAACTGAA2641GAAGCCAATG AAGTTTGTCT ACATTATATA TTACACAAAT TGGCAGGGTA TTTAAATATG2701CTTTTATTTT TATACGCATC TGTGAAGAAT CTGAATTGAA CAGTAAGAAT TAGAAAACTA2761TCTTTTGAAT GACTGAATAT AGACCTATTC ATAAAGAAAT TTAAAACTGT GTTTTTAAAC2821AGTACAGCAA AACAAGCCTT TAGAGTTAAT ATGTAACTTA ACTGTAACAT GTTGAAATAA2881TAAAAGAAAT GAATAGATGA ACAAATGACT GAGTTACCAA ATGGAAAGAT TTGATGTATT2941GTAGGTCATT GGCAGTGTAC CTTTTCATGT TTAAGATAAC ACATTTTAGG AAGTCATCAT3001TTTCAACAAA TTTTTTAAAA ACTTTTTTTA GCCTCAACAT TTTTCTATTT AAATTACATG3061TTTGTAATGA CAATTTAACT ACTGAATGTT TTATCGTAAG TTATCTCTTT CCTTAATTAG3121TACCACAATC ACACAAATTA AAACAAGCAC AGGTTATTAA CATCTCCGTG AAACTAATTT3181TAACCATGAC TATATTTCTG GACACGTAAC ATGAAAGATT CAGAAAGAAG TGCTGCTCAT3241CTGCCTTAAA ATTCAGCGTA TGCAAATTAT TGAAGAGAAC AAGCATAATG GTTATCAACA3301CATACTCTGT AGCCCAATGG CCTAGGTTCA ATCCTCACTC TGTGACTTTA GGTGAATCAC3361TGTGCCATTT TACAGTCTCC TCTTCTGCAA ACTAGAGATA GTAGTATCAG TTTCATAGGG3421TCACCATGAA GATTAAATGA AAAAGTGTGT CTACAGAACT CAGAACAGTG CCTGACATGT3481GTAAGACCCT AATAAATGCC ATTATTATTA TTATTATTAT TATTATTATT ATTATTATTA3541TGTAGGGGAC CTGGAGCCTT GAGGGAAATA AACTTATTGG AAAATTCAAA GGGACAGACA3601ATGGAAACGA ACTGAATACT GTCCGAGAAA TTATAGGTGA TGAACTAGTC CAGGTGAGTT3661GTCAAATTTA TAGCTATTTT CAAAAGGCAA AAATTACTAC AAAACAATAA TTTTTGTCAC3721TGCTGAGCCA GATCTTCAGT AAACTGACTA CTTCTTTTCT CATAAATCTT ACTGATTTTA3781AAAATATTGT ATAGCTATTT TCTGATGCCT ATTTACTAAA GACAACTTAT ATATGTCAAA3841TAATCAATGC CTATTTTAAC TGAAAATATA AATGACTACA AACCAACATG TGTTTTAAAA3901TGGCTGTATC CCATATCTGT ATAAATCTTG CTATCAAGTA CAAGAAAAAA TTGTATAAAC3961TCATACTCAT ATAATATATA TGAATATATA ATATAAAAAT AGTATAAACT CATATACTAT4021AAAACTATAA TACTACTTTT TCTTAACTTA GATGTAAACC TTAAAGATAA ATTCTTCTGT4081TTGTTAACAC CTTTCAGACT TATGTGTATG AAGGAGTAGA AGCCAAAAGG ATCTTTAAAA4141AGGATTGAGC ATTATTCTTG GCGCACAGTC CAAAATACAA ATTGGACAGA AGATCTATAT4201TGTACCAGAA CTGTTTATTT CACCCCATCA AGTATAAGGT TACTGATTGA TTGGTCCTTT4261TATAAACATT GGTATATTTC CATTCATGCC AAAGCAAAAG AAGTAAAAGC TAATTAGGAT4321TTAATTTGTT TTATATTCTC TAAGATATAT ATTTACTAAA AGAATTTGTG ACATTTTAAA4381AAACAAAAAT AAATATTGCA TCCATGTTGC TTTATATGTA GCCTTGCCTT TTAAAAGAAA4441AAGTATGTGA ATATGAATTG ACAGATTGTT TTCGTAGAGA GAGGGTCTTA CTCTTTCACT4501CAGGCTGGAA TGCAGTGGAG AGATCATAGC TCACTGTAAC CTCAAACTCC TGGACTCATG4561CAATCTTCCT GCCTCAGGCT TCTGAGTAGC TAGGACTATG GGTACATTCC ACAGTGCCCA4621GCTAATTTTT GTTTTGTTTT CTTTTTATTT TTTTTAGAGA TGGGGTCTTG CTATATTGCC4681CAGGCTGGTC TTGAACCCCT GGCCTCAAGC AATCCTCCTG CCTCAGCCTC TCAAGTTGTT4741TTTTTCTTTA CATTTGATAA ACTAAAAGCA TAGGCTGCAT ATGAGTCTTT AACATCTTGA4801ACTGGTTGTG AATAATTTTC TGGCACTGGT TGTAAGTAAT ATCTATTATT ATAAAAATAA4861TATATGCTCA ACCAGAAAAC TTAGAAATAA GAAACACAAA TGTAAAATAA GTATTTCCAT4921AACTCATAAT CCAGAGATAA TTGCCATTCT GATTTTGATA GATATCCTCT CAGCTCTCTT4981CCCTGGGGGC AGATATTTCC CAATACATAC CACTTTGAAT AGGATGATAG GAAATAAATG5041ATGTACTACA TTAAATTAAA TTATTGTATT ACATTTTTGT ACACATCAGT CATTCCCAGG5101CTTGGCTGAA AATCAGGATC ATCTGAGAAA CTTAAACAAT TTCTGCATTC TTAATCTCCA5161CTGTTATTCT ATTATATCAG AATCGCTAAT AGAACCAAGA ATTCGENBANK ID: X16277DNA LINEARDEFINITION HUMAN GENE FOR ORNITHINE DECARBOXYLASE ODC (EC 4.1.1.17).VERSION X16277.1 GI:35137MRNA JOIN(795..1001,3858..3967,4073..4191,4475..4648,4855..5027,5286..5420,5551..5632,5809..5892,6948..7110,7193..7305,7399..7613,8254..8740)1GGATCCGGGT CCCCTCACGC TCCTGGCTGA GTCCCTGGCT TCACAGGGGA AACTACCTCC61GCAGGCCAGG ACCCATCTAG TTACACGATA CCTCGATGTT ACAAAGACGA GGCTTCCAGC121GCGGGGGCGT GGAGGCGGCT GCCAGCCCTG CCCGCAGCGT GCTGGCGACC CCCGGGACGC181CCCTTCCCTC CCGCGCCTCT GCTCCCTAGC TGGTGGGAGC AGAGCGCACC GGGATCACTT241CCAGGTCCCT TGCACCGGAG GAATGGGCGG CAGCAGGGTC CGGAGTCGGC CCGGCGGGGC301CCACGTGGCC AGCACATCGG TCCTCCGCTC GCGATTTCCC TTTTCCGCTC TCGGGCACGA361GGTACTGAAC GCCAGGTGGA AGCACAGCTG TGCAGGTACA GGCTCTGCCG TTCAGCTGCC421GCGGGCCGGG GCCGGGGCCT GCGGCGTCGT GCGCGTGCGC GGACCAGTTC CAGGCGGGCG481AGACCGCCGC AGGGCGGGGC GGGGCGAGGC GGCCGCAGGG CGGGGAGGGC GGGGAGAGGC541GGCCGCAGGG CGGGGAGGGC GGGGCGCGAA GCCGGGGGCG GGGGCCACGC GTGGGGCAGG601CGGTGCTCGG CTCGGCTGAC GTCGGCCCGC CGGCGCCCCA CCAGCTCCGC GCGGGCCCGG661GTTGGCCACC GCCGGGCCCC CGCCCCTCCC CCGGCCGTGT CCCGGCCGGA ACCGATCGTG721GCTGGTTTGA GCTGGTGCGT CTCCATGGCG ACCCGCCGGT GCTATAAGTA GGGACCGGGG781TGCCGTGGGG CTTTGTCAGT CCCTCCTGTA GCCGCCGCCG CCGCCGCCCG CCGCCCCTCT841GGCACCAGGT CGGGCGCCAC CTCGGGCCGG CGTCTCCGGC GGGCGGGAGC CAGGCGCTGA901CGGGCGCGGC GGGGGCGGCC GAGCGCTCCT GCGGCTGCGA CTCAGGCTCC GGCGTCTGCG961CTTCCCCATG GGGCTGGCCT GCGGCGCCTG GGCGCTCTGA GGTGAGGGAC TCCCCGGCCG1021CGGAGGAAGG GAGGGAGCGA GGGCGGGAGC CGGGGCGGGC TGCGGGCCCC GGGCCCCGGG1081CACGTGTGCG GCGCGCCTCG CCGGCCTGCA GAGACACGTG GTCGCCGAGC GGGCCACGAC1141CTTGAGGCGC CGCTTCCTCC CGGCCCGGGG TTCTCCCGCG GCTGGATAAG GGTGATCCGG1201GCGCCTCGTT CTGCCCCCGT CTTCACAGCT CGGGGCTGGA GGGGCCTAGG GGAGACCCAC1261CCGGAGACCC TGCGGCCCCG CGCCGGCCTC TTTCCCAACC CTTCGGCGGC CGCGCGCTGG1321CCGGGGAGCC GTTGGGGAGG CCCTGGCGGC CGCGCAGCAG GTGCAGGGGC GCAGAGCCTG1381GGCTCGCCTT GGTACAGACG AGCGGCCCCG GCCTTGGCGC CTTCAGTTTC CTTCCAGTTT1441TTATTTTCGC TGTGTCTACA GAGCAGATGA CACCAATTTG GAAACCCGCG AGAGTGGGTA1501GAGCTAAGAT AGTCTTGCTG TAGTAGCTGT GATATTAGAT GCTCGGCCAT GACTTAGAGG1561TGTTTATTTA AGGACTGTGA ATGACTCGGT GATTTCGGAA AAGCTTGGCT TAGATGAACG1621GACATACACA GGGGAGACAG CCCTAAGGTT TGCAGAAAAG GCTGATTGTG CTGTTTGCGA1681AGTCGAAATA ATTGGTGAAA GTGTAGAAGG CAGAACCTCT CAGGAATGTC TGOGGAGGAC1741AAAGAATGTG TTGGCTGACT TTGTTTAAAC ATAAAATTGG GCAGACTTTA ATTGATTTGT1801GAAATTTTTT TCAAAGTTTG TTTGAATTAG CCCCTATCTC TTCTAACATT ATCCTCTTGT1861GCTAATTGAT TGACCATTTT AAATAACTTA GGTGTTACAG AAAGACCGAA AGGTGTTCTT1921CAGTAAAATA TATTCAAGTA AGTTACTTAA GTAACGCCTT AAAAGATACA GAAAAGCAAA1981AAAGTATTGG CGTATTAAAA AGAAATCAAA ACTTTCCAAG TTTAGGCCTG AACATTGCCT2041TAAAAATATT TAATAAGGCC TCAAATGACC CAGTCCGAGA CTGCATGAGC CTATTTATTA2101TTAAATTGTA AATATTCTTC ATATAAACAA AAATATATAA CCATGTCTGT AACAAAAATG2161GTTTTGCTAG CGTTGTTACT CTCTTCCCTT CTCCGAGGGG TGATTTAGGC AACTTCGGAG2221GTTGACAATG CCAAGCAGTC ACAATAGATA GAGCTTTAAA GCAAATTCTA TGCATGGGTT2281TGGATTTATG ACAGGCCCGT CACCCTGGGC CTGTCATAGT ACCCCATGCC AGAGCAAACT2341GTGTCCCCGA ACCATTGCCT GGCCTCTGTG CCCGTAGGCT GCTGGCACTG AAGTGGGTTG2401CACAGTGGAA AAGAAGAAAG CTCTACCTGG CAGAAATTTT TAAAGGTTAA AATAAATAAT2461TTTAAGAAAG CTGGTTCACA AGGTGCCACA TTTGATGAAA GCAAAATACA GTGGCTTTTA2521TTGTTACTAG AGTGATGTTC TTGCTTGTTT TTCTTTTTTG GTGAAGTTAG CCCCAAATTA2581TTCTCATAGC TAAGCAAATA CGAGAGTGAC TGTAAGGACA GTTGGCATTC CCGGAATTGC2641TAAACTTGGT AGGCAACGCT GGTTTAAGAA TACTGAGTTC TAGCCGGGCG TGGTGGCTCA2701CGCCTGTAAT CCCAACACTT TGGGAGGCTG AGGCAGGCGG ATCACCTGAG GTCGGGAGTT2761GGAGACCAGC CTGACTAACA TGGAGAAACG CCATCTCCAC TAAAAATATA AAATTAGCCA2821GGCCCCGGGT GTGGTGGCAC ATGCCGGTAA TCCCAGCTAC TCGGGAGACT GAGGCAGGAG2881AATCGCTTGA ACCCAGGAGG CGGAGGTTGA GGTGAGCCGA GATCATGCCA TTGCACTCCA2941GCCTGGGCAA CAAGAGTAAA ACTCTGTCTC AAAAAAAAAA AAAAAAAAAT ACTGAATTCT3001GATCAGGTAA CAGCAACTGT AATACAATGT GATAAGTTGA CTTGAAGATT ACAGTTTTTA3061AGAAGTATAT ACCCAGCTAA TACATGAAAA TTAACTCCTA AAATCTCAAA TGCTCCAGAC3121ATTTCCATGA TGCCTGTTGG TCAGTAAAAA TCATTCTAAG ACTTAGTGGA AGTAGGAAAT3181GTTTGTATGG CTGTGTATAA AGGCTATAAT GTAATCCCAG CACTTTGGAA GACCGAGGCG3241GGACGATCAC CTGGGGTCAG GAGTTTGACA CCCACCTGGA CAACGTGGTG AAATCCTGTC3301TCTACTAAAA ACACAAAAAT TAGCCGGGCA TGGTGCCAGG CGCCTGTAAT CCCAGCTGCT3361GGGGAGGCTG AGGCAGGAGA ATCGCTTGAA CCCGGGAGGC AGAGGTTGCA CTGAGCCAAG3421ATTGCACCGC TCCACTCCAG CCTGGGTGAC AACCTGAGAC TCTGTCTCAA AAAAAATAAA3481AAAGTCTATA ATGCTATTTT AAGTTTCTAA GGAACTGAAA CTGCTCTGAA ATAAATCAGA3541CCATTATAAG ACTTTTTTCC ATATCAGTGA GCTAAGTGCA GATAAGCTTC TGAAACTTCC3601ATGCTAGATT TTTTTGGTAC AAATATTTGA AATGCTTAGT GTCCTGCCTT GGAAAAACCT3661GGTATTTTTT GTTGTCTCCT TATACTGCCA AGGTTTATGC AATCATGTAC CTTATGCCAA3721GTAATAATTA GGATGACCAG GCCAGTGAGT GGTTCATATC CCGGGCATGA TTAGCTCTGC3781GTGTGCTCAG CCAGTGCCCC ATCTTCAACT CGATGTGTTC CTAACGTAGA CACCAAATTC3841CCTATTTTAT TTCTCAGATT GTCACTGCTG TTCCAAGGCC ACACGCAGAG GGATTTGCAA3901TTCCTGGAGA GTTGCCTTTG TGAGAAGCTG CAAATATTTC TTTCAAITCC ATCTCTTAGT3961TTTCCATGTA AGTATTCAGT TTACATTTAT GTTGCAGGTT AATCTTAAGA ATTGTATTGC4021TAAGGCTTCT AAGTGAATTT CTCCACTCTA TTTGCATTTT GTTGCATTTC AGAGGAACAT4081CAAGAAATCA TGAACAACTT TGGTAATGAA GAGTTTGACT GCCACTTCCT CGATCAAGGT4141TTTACTGCCA AGCACATTCT GGACCAGAAA ATTAATGAAG TTTCTTCTTC TGTAAGTATA4201TGAGGCCCAT CCTGGCAGTG CAGCTGAGAG TCCCAGGCAA GTGGAAAACT TTGGCAAGGT4261CTAAGGAAGA GCAATGAGGC TTACATGTCT TGTTATGGAA TGTAGAAATT AATTCACTGG4321TGGTAAATTA ATAGTGATAA TGCTGATACT CATATCAGTC GCTAGACTCA AAAGAGCAGG4381ATTCATTGTG ACTGATGGGA ATGAAGGTCG CTGGCTATTG GTGTGGTGTG TGGTGAGGCT4441GCTAGTGAGT CACCTGTGAC CACTCTTGTT TCAGGATGAT AAGGATGCCT TCTATGTGGC4501AGACCTGGGA GACATTCTAA AGAAACATCT GAGGTCGTTA AAAGCTCTCC CTCGTGTCAC4561CCCCTTTTAT GCACTCAAAT GTAATGATAG CAAAGCCATC CTGAAGACCC TTGCTGCTAC4621CGGGACAGGA TTTGACTGTG CTAGCAAGGT AAGCGATAGC AGCAGGCCTC AAAAGCGTTG4681TATAAAATGC GCCTGGTATT CCCCACGAGG CACATACAAG TTGTGTTTTT TGGGCAATAA4741ATGCTCACTA AAGGCAAATG GGCCGGGGGG GTACATGACA ACTTCCCATG CTTTTCTGTT4801TATTCCACGT GTTAAGCCAC ATATGGATAG CATGACACCA CTCTTCTTTT TCAGACTGAA4861ATACAGTTGG TGCAGAGTCT GGCGGTGCCT CCAGAGAGGA TTATCTATGC AAATCCTTGT4921AAACAAGTAT CTCAAATTAA GTATCCTGCT AATAATGGAG TCCAGATGAT GACTTTTCAT4981AGTCAAGTTG AGTTGATGAA AGTTGCCAGA GCACATCCCA AAGCAAAGTG AGTTATTCCC5041CCATCTGAGG GCAAGATCGG GAGCATAAGA TATCTGGATT CTTATCAAAC AAACTTAAAT5101TTCTGATTAT TATATTTCTA TACTTTAGTA GAAAGTAGTT GAAACCCCCA TTGAGTCATG5161AAGCCTGGGA CTCAAACTAC AGAATATATC AGCGACAGTA TTTAGAACAG GATTGTTTTT5221ATTTTAATTG TGGCTATAAG TGAACATCTA TCATGAGACA TTTGCTGCAC TTTCCTTGCT5281TGTAGGTTGG TTTTGCGGAT TGCCACTGAT GATTCCAAAG CAGTCTGTCG TCTCAGTGTG5341AAATTCGGTG CCACCCTCAG AACCAGCAGG CTCCTTTTGG AACGGGCGAA AGAGCTAAAT5401ATCGATGTTG TTGGTGTCAG GTGAGATTTT GGTGGGATAG CTAGAGGTCA AGACATTGAA5461CAGTTTGAGT TTTACAGGCT TTCTCCTAGT GTTTGCTATT ATTTAAGAA ATACTAAGAC5521ACAGTGTCTC GTCTCTTTAT TTTACCCCAC CTTCCATCTA GGAACCGGCT GTACCGATCC5581TGAGACCTTC CTGCAGGCAA TCTCTGATGC CCGCTGTGTT TTTGACATGC GGGTGAGTAT5641ACGTGACCCT GTTAGGCAAG GGCGGGACAC AACTGACAAT AACTAGTCTT AATTCTAGAG5701TTAACTTTTT A2GGCAGTTG GTTCTCTATT ACATGGGTTT CAGCCTATCT GCTGCATACA5761TTTTTGTTAT TACCTGTGGA TCTGGCTGAC TTATTTTCTT CATTCTAGGC TCAGGTTGGT5821TTCAGCATGT ATCTCCTTGA TATTGGCGGT GGCTTTCCTG CATCTGAGGA TGTGAAACTT5881AAATTTCAAG AGGTAATTTA GAACAAAACT GTAATACTCA GTAGCCGTTC TAATAAATTC5941CTTTTTGGAA TATTTCAAAA TTTAAGTGTC TTAACTAATA CCACAATGGG CTGAAGTGTC6001TTGGTGTGAT ATTTTGAGTG ATTTCTTTGT GCTGTCTGAC ATTACACTTG ATACCATTTG6061GTTTTCTAAA GTGTGAATCA GCTTTCCCAG AAGTCTTGGA TAAATGGTTA CATTGGAAAT6121CATGGCTCAC ACCTGTAATC CACCACTTGG GCAGGCCAAG GTGCTAGGAT CACTTGAGCC6181CAGGAGTTTG AGACCAGCCT GGGCAACACA GTGAGACCCG ATCTCTACAA AAAAAATTTT6241AAAATTAGCC TGGTGTGGTG GCCGGCACCT GTAATCCCAG CTACTTGGAA GGCTGAGGTG6301CGAGGATCAC TTGAGCCCAG GAGGTTGAGG CTGCAGTGAG CCATGATCAT GCCACTGCAC6361TCAGCCTGGG CTACAGAGTG AGACCCTGTC TCAAAAAAAA AAAAGAAAAA GCATGTTGCT6421GTGGGCTTCC TAGAGAATAT GCTGACTGTA GCACATCATC ACCCCAAATG TGCTTTCCTA6481GACCTATGCT TCCTCTCCTT AAAATACTTG AAATCTTTAG TCACTTACCA AGTTAACCCA6541TTATATTGGT GCTTGAATTT ATAAAATACA TCCACATGGT TTGTTAAAAT CATGACGTAG6601GCAGAATAGG ATTTTTATCC TGTTGGCATC TATTTGTTAA AATGTTTTCA CATCTTGATC6661CCTTCCTAGG TAGTAGTTAG TTGCGTACTG TTCTTTGATA AAAATCATAC CCATAACATC6721CTAAAGGACA TAGGGTGCCT GGAGGGGAAT GAAAACGAGC CACGTGGGAT ATGTAGCCTG6781GTTTTCAGGG AGATGTTGAT GTTTTTTTGC TTTTGTTACT TTAATGATAA ACCTGTCTGT6841TGATGCCTGG TCTCATGATG TCATGTCACA AGGCCCTGTG ATGTTACTCC CCCATGTGAA6901TTTCCCACAA TGAAGGCTGC TCTTTCTTTT CTGTTTCACT CTCTTAGATC ACCGGCGTAA6961TCAACCCAGC GTTGGACAAA TACTTTCCGT CAGACTCTGG AGTGAGAATC ATAGCTGAGC7021CCGGCAGATA CTATGTTGCA TCAGCTTTCA CGCTTGCAGT TAATATCATT GCCAAGAAAA7081TTGTATTAAA GGAACAGACG GCCTCTGATG GTATGTATAA AGGACGAATC ACTTCATGTA7141TAACTGAAAG CTGATGCAAA AAGTCATTAA GATTGTTGAT CTGCCTTTCT AGACGAACAT7201GACTCGAGTG AGCAGACCTT TATGTATTAT GTGAATGATG GCGTCTATGG ATCATTTAAT7261TGCATACTCT ATGACCACGC ACATGTAAAG CCCCTTCTGC AAAAGGTAAT TTCTGAGCAT7321ACTGTATAAA ACAATTAAGA GGACTGGTCA CAACACCTGT AATTAACTAC TACTTCCTCT7381CTCCGTCTCT TTATATAGAG ACCTAAACCA GATGAGAAGT ATTATTCATC CAGCATATGG7441GGACCAACAT GTGATGCCCT CGATCGGATT GTTGAGCGCT CTGACCTGCC TCAAATGCAT7501GTGGGTGATT GGATGCTCTE TGAAAACATG GGCGCTTACA CTGTTGCTGC TGCCTCTACG7561TTCAATGGCT TGCAGAGGGC GACCATGTAC TATGTGATGT CAGGGCCTGC GTGGTAAGTA7621AGCCATGCAT GTTGATGGTG CTGCCAAGAA TAGGCACCTT CTTGGATGTC TGCTTCTTGT7681CTAGACGAAT AAGAAATTGT CTTGCCTAAG ATTAAATATA TATGGATATT TTTCCTAAGA7741AAAGTTTTAG AAAAGACTGA TGAGTGTATT TCTATGTAAT TGCAATATAT TTAAGTTCAT7801GCCATGTGTC TTGTGGTTTC CTTATTACCA AAACGGTGAC TGAAGAAACG CTTGCTTTAG7861AAATACATTG AATTGGCCAG GTGTGCTGGC TCACACCTGA AATCACAACA CATTGGGAGG7921CCAAGGCAGA AGGATCACTT GAGCCCAGGA GTTCGAGCCT GGGCAACATA GTGAGACCCT7981GTCTCTACAA AAAATTAAAA AATTAGTTGG CCATGGTAGT GGGCGCCTGT AGTCCCAGCT8041GCTTGGCTAA GGTGAGAGGT TTGCTTGAGC CTGGGAGGTT GAGGCTGCGG TGAGCTATGA8101TAGCACCATT GTATTCCAGC CTGAGTAACA GAGAAAGACC CTGTCTCAGA AAAAAAAAAA8161ATACATTGAA TTGTTTCCTG ATGGGAAGTA AATACTCTCA TGCCCAGTTA GGAGTGAGTC8221AGGGTTTTTA ATATGCCACT TTTTCTTTCT CAGGCAACTC ATGCAGCAAT TCCAGAACCC8281CGACTTCCCA CCCGAAGTAG AGGAACAGGA TGCCAGCACC CTGCCTGTGT CTTGTGCCTG8341GGAGAGTGGG ATGAAACGCC ACAGAGCAGC CTGTGCTTCG GCTAGTATTA ATGTGTAGAT8401AGCACTCTGG TAGCTGTTAA CTGCAAGTTT AGCTTGAATT AAGGGATTTG GGGGGACCAT8461GTAACTTAAT TACTGCTAGT TTTGAAATGT CTTTGTAAGA GTAGGGTCGC CATGATGCAG8521CCATATGGAA GACTAGGATA TGGGTCACAC TTATCTGTGT TCCTATGGAA ACTATTTGAA8581TATTTGTTTT ATATGGATTT TTATTCACTC TTCAGACACG CTACTCAAGA GTGCCCCTCA8641GCTGCTGAAC AAGCATTTGT AGCTTGTACA ATGGCAGAAT GGGCCAAAAG CTTAGTGTTG8701TGACCTGTTT TTAAAATAAA GTATCTTGAA ATAATTAGGC ATTGGGACGT TTTTATGGTG8761TGTTCATTCC AGACAGTTCA CGAATCCCGT ATAGCTCGCT CTGATTCTCA GAGAACAATG8821AGTGGGTCCA CCCACACACA GGTAGGAGGA CAGGTGAGAC GGAAGCCCCA TCCTCCCATG8881TGGACGGTGC ACATCTGCTC AGCCCACCCC ACATGTCCAG AGTTGGCTGC AAACTCCTTG8941TCCAGAGCCT CTGGTGGTGG GACCTACTTA AGTCTGACGG ACCTGTCCTG TCCAGGCCAG9001TGCCCAGGGA AGGTGTGGGA GGCCCTTTGA GCCTGGCCTG CAGGENBANK ID: X57522DEFINITION H. SAPIENS RING4 CDNA.VERSION X57522.1 GI:36060CDS 31..2457/CODON_START=11GCGGCCGCTT TCGATTTCGC TTTCCCCTAA ATGGCTGAGC TTCTCGCCAG CGCAGGATCA61GCCTGTTCCT GGGACTTTCC GAGAGCCCCG CCCTCGTTCC CTCCCCCAGC CGCCAGTAGG121GGAGGACTCG GCGGTACCCG GAGCTTCAGG CCCCACCGGG GCGCGGAGAG TCCCAGACCC181GGCCGGGACC GGGACGGCGT CCGAGTGCCA ATGGCTAGCT CTAGGTGTCC CGCTCCCCGC241GGGTGCCGCT GCCTCCCCGG AGCTTCTCTC GCATGGCTGG GGACAGTACT GCTACTTCTC301GCCGACTGGG TGCTGCTCCG GACCGCGCTG CCCCGCATAT TCTCCCTGCT GGTGCCCACC361GCGCTGCCAC TGCTCCGGGT CTGGGCGGTG GGCCTGAGCC GCTGGGCCGT GCTCTGGCTG421GGGGCCTGCG GGGTCCTCAG GGCAACGGTT GGCTCCAAGA GCGAAAACGC AGGTGCCCAG481GGCTGGCTGG CTGCTTTGAA GCCATTAGCT GCGGCACTGG GCTTGGCCCT GCCGGGACTT541GCCTTGTTCC GAGAGCTGAT CTCATGGGGA GCCCCCGGGT CCGCGGATAG CACCAGGCTA601CTGCACTGGG GAAGTCACCC TACCGCCTTC GTTGTCAGTT ATGCAGCGGC ACTGCCCGCA661GCAGCCCTGT GGCACAAACT CGGGAGCCTC TGGGTGCCCG GCGGTCAGGG CGGCTCTGGA721AACCCTGTGC GTCGGCTTCT AGGCTGCCTG GGCTCGGAGA CGCGCCGCCT CTCGCTGTTC781CTGGTCCTGG TGGTCCTCTC CTCTCTTGGG GAGATGGCCA TTCCATTCTT TACGGGCCGC841CTCACTGACT GGATTCTACA AGATGGCTCA GCCGATACCT TCACTCGAAA CTTAACTCTC901ATGTCCATTC TCACCATAGC CAGTGCAGTG CTGGAGTTCG TGGGTGACGG GATCTATAAC961AACACCATGG GCCACGTGCA CAGCCACTTG CAGGGAGAGG TGTTTGGGGC TGTCCTGCGC1021CAGGAGACGG AGTTTTTCCA ACAGAACCAG ACAGGTAACA TCATGTCTCG GGTAACAGAG1081GACACGTCCA CCCTGAGTGA TTCTCTGAGT GAGAATCTGA GCTTATTTCT GTGGTACCTG1141GTGCGAGGCC TATGTCTCTT GGGGATCATG CTCTGGGGAT CAGTGTCCCT CACCATGGTC1201ACCCTGATCA CCCTGCCTCT GCTTTTCCTT CTGCCCAAGA AGGTGGGAAA ATGGTACCAG1261TTGCTGGAAG TGCAGGTGCG GGAATCTCTG GCAAAGTCCA GCCAGGTGGC CATTGAGGCT1321CTGTCGGCCA TGCCTACAGT TCGAAGCTTT GCCAACGAGG AGGGCGAAGC CCAGAAGTTT1381AGGGAAAAGC TGCAAGAAAT AAAGACACTC AACCAGAAGG AGGCTGTGGC CTATGCAGTC1441AACTCCTGGA CCACTAGTAT TTCAGGTATG CTGCTGAAAG TGGGAATCCT CTACATTGGT1501GGGCAGCTGG TGACCAGTGG GGCTGTAAGC ACTCCGAACC TTCTCACATT TCTTCTCTAC1561CAGATCCAGT TCACCCAGGC TGTGGAGGTA CTGCTCTCCA TCTACCCCAG AGTACAGAAG1621GCTGTGGGCT CCTCAGAGAA AATATTTGAG TACCTGGACC GCACCCCTCG CTGCCCACCC1681AGTGGTCTGT TGACTCCCTT ACACTTGGAG GGCCTTGTCC AGTTCCAAGA TGTCTCCTTT1741GCCTACCCAA ACCGCCCAGA TGTCTTAGTG CTACAGGGGC TCACATTCAC CCTACGCCCT1801GGCGAGGTGA CGGCGCTGGT GCGACCCAAT GGGTCTGGGA AGAGCACAGT CGCTGCCCTG1861CTGCACAATC TGTACCAGCC CACCGGGCGA CAGCTGCTGT TGGATGGGAA GCCCCTTCCC1921CAATATGAGC ACCGCTACCT GCACAGGCAG GTGGCTGCAG TGGGACAAGA GCCACAGGTA1981TTTGGAAGAA GTCTTCAAGA AAATATTGCC TATGGCCTGA CCCAGAAGCC AACTATGGAG2041GAAATCACAG CTGCTGCAGT AAACTCTGGG GCCCATACTT TCATCTCTGG ACTCCCTCAG2101GGCTATGACA CAGAGGTAGA CGAGGCTGGG AGCCAGCTGT CAGGGGCTCA GCGACAGGCA2161GTGGCGTTGG CCCGAGCATT GATCCGGAAA CCCTGTGTAC TTATCCTGGA TGATGCCACC2221AGTGCCCTGG ATGCAAACAG CCAGTTACAG GTGGAGCAGC TCCTGTACGA AAGCCCTGAG2281CGGTACTCCC GCTCAGTGCT TCTCATCACC CAGCACCTCA GCCTGGTGGA GCAGGCTGAC2341CACATCCTCT TTCTGGAAGG AGGCGCTATC CGGGAGCGGG GAACCCACCA GCAGCTCATG2401GAGAAAAAGG GGTGCTACTG GGCCATGGTG CAGGCTCCTG CAGATGCTCC AGAATCAAAG2461CCTTCTCAGA CCTGCGCACT CCATCTCCCT CCCTTTTCTT CTCTCTGTGG TGGAGAACCA2521CAGCTGCAGA GTAGCAGCTC CCTCCAGGAT GAGTTACTTG AAATTTGCCT TGAGTGTGTT2581ACCTCCTTTC CAAGCTCCTC GTGATAATGC AGACTTCCTG GAGTACAAAC ACAGGATTTG2641TAATTCCTAC TGTAACGGAG TTTAGAGCCA GGGCTGATGC TTTGGTGTGG CCAGCACTCT2701GAAACTGAGA AATGTTCAGA ATGTACGGAA AGATGATCAC CTATTTTCAA CATAACTGAA2761GGCATATGCT GGCCCATAAA CACCCTGTAG GTTCTTGATA TTTATAATAA AATTGGTGTT2821TTGTGENBANK ID: D00017.1DEFINITION HOMO SAPIENS MRNA FOR LIPOCORTIN II, COMPLETE CDS.VERSION D00017.1 GI:219909CDS 50..1069/CODON_START=11CATTTGGGGA CGCTCTCAGC TCTCGGCGCA CGGCCCAGCT TCCTTCAAAA TGTCTACTGT61TCACGAAATC CTGTGCAAGC TCAGCTTGGA GGGTGATCAC TCTACACCCC CAAGTGCATA121TGCGTCTGTC AAAGCCTATA CTAACTTTGA TGCTGCGCGG GATGCTTTGA ACATTGAAAC181AGCCATCAAC ACCAAACGTG TGGATGAGGT CACCATTGTC AACATTTTGA CCAACCGCAG241CAATGCACAG AGACAGGATA TTGCCTTCGC CTACCAGAGA AGGACCAAAA AGGAACTTGC301ATCAGCACTG AAGTCAGCCT TATCTGGCCA CCTGGAGACG GTGATTTTGG GCCTATTGAA361GACACCTGCT CAGTATGACG CTTCTGAGCT AAAAGCTTCC ATGAAGGGGC TGGGAACCGA421CGAGGACTCT CTCATTGAGA TCATCTGCTC CAGAACCAAC CAGGAGCTGC AGGAAATTAA481CAGAGTCTAC AAGGAAATGT ACAAGACTGA TCTGGAGAAG GACATTATTT CGGACACATC541TGGTGACTTC CGCAAGCTGA TGGTTGCCCT GGCAAAGGGT AGAAGAGCAG AGCATGGCTC601TGTCATTGAT TATGAACTGA TTGACCAAGA TGCTCGGGAT CTCTATGACG CTGGAGTGAA661GAGGAAAGGA ACTGATGTTC CCAAGTGGAT CAGCATCATG ACCGAGGGGA GCGTGCCCCA721CCTCCAGAAA GTATTTGATA GGTACAAGAG TTACAGCCCT TATGACATGT TGGAAAGCAT781CAGGAAAGAG GTTAAAGGAG ACCTGGAAAA TGCTTTCCTG AACCTGGTTC AGTGCATTCA841GAACAAGCCC CTGTATTTTG CTGATCGGCT GTATGACTCC ATGAAGGGCA AGGGGACGCG901AGATAAGGTC CTGATCAGAA TCATGGTCTC CCGCAGTGAA GTGGACATGT TGAAAATTAG961GTCTGAATTC AAGAGAPAGT ACGGCAAGTC CCTGTACTAT TATATGCAGG AAGACACTAA1021GGGCGACTAC CAGAAAGCGC TGCTGTACCT GTGTGGTGGA GATGACTGAA GCCCGACACG1081GCCTGAGCGT CCAGAAATGG TGCTCACCAT GCTTCCAGCT AACAGGTCTA GAAAACCAGC1141TTGCGAATAA CAGTCCCCGT GGCCATCCCT GTGAGGGTGA CGTTAGCATT ACCCCCAACC1201TCATTTTAGT TGCCTAAGCA TTGCCTGGCC TTCCTGTCTA GTCTCTCCTG TAAGCCAAAG1261AAATGAACAT TCCAAGGAGT TGGAAGTGAA GTCTATGATG TGAAACACTT TGCCTCCTGT1321GTACTGTGTC ATAAACAGAT GAATAAACTG AATTTGTACT TTGENBANK ID: M10277.1DNA LINEARDEFINITION HUMAN CYTOPLASMIC BETA-ACTIN GENE, COMPLETE CDS.VERSION M10277.1 GI:1779671GCCCAGCACC CCAAGGCGGC CAACGCCAAA ACTCTCCCTC CTCCTCTTCC TCAATCTCGC61TCTCGCTCTT TTTTTTTTTC GCAAAAGGAG GGGAGAGGGG GTAAAAAAAT GCTGCACTGT121GCGGCGAAGC CGGTGAGTGA GCGGCGCGGG GCCAATCAGC GTGCGCCGTT CCGAAAGTTG181CCTTTTATGG CTCGAGCGGC CGCGGCGGCG CCCTATAAAA CCCAGCGGCG CGACGCGCCA241CCACCGCCGA GACCGCGTCC GCCCGCGAGC ACAGAGCCTC GCCTTTGCCG ATCCGCCGCC301CGTCCACACC CGCCGCCAGG TAAGCCCGGC CAGCCGACCG GGGCATGCGG CCGCGGCCCT361TCGCCCGTGC AGAGCCGCCG TCTGGGCCGC AGCGGGGGGC GCATGGGGCG GAACCGGACC421GCCGTGGGGG GCGCGGGAGA AGCCCCTGGG CCTCCGGAGA TGGGGGACAC CCCACGCCAG481TTCGCAGGCG CGAGCCCGCG CTCGGGCGGG CGCGCTCCGG GCGTGCCGCT CTCGGGGCGG541GGGCAACCGG CGGCGTCTTT GTCTGAGCCG GCCTCTTGCC AATGGGGATC GCACCCTGGG601CGCGGCGTAG CCCCCGTCAG GCCCGGTGGG GGCTCGGGCG CCATGCGCGT GCGCGCTGGT661CCTTTGGGCG CTAACTGCCT GCGCGCTGGG AATTGCCGCT AATTGCCCGT GCGCGCTGCG721ACTCAATGCC GCTAATCGCG CGTCCGTTCT GGGGCCCGGG CCCTTGCGCC ACTTCCTGCC781CGAGCCGCTG GCGCCCGAGG GTGTGGCCGC TGCGTGCGCG CCCGCGACCC GGTCGCTGTT841TCAACCGGGC GGAGGCCGGG CTCCCGCCCC GTTCGGAGGG GGTTGGGGCC TGGCTTCCTG901CCGCCCGCCG CGGGCACGCC TCCGACCAGT GTTTGCCTTT TATGGTAATA ACGCGGCCGG961CCCCCCTTCC TTTGTCCCCA ATCTCGCCGC GCGCCGGCGC CCCCTGGCGG CCTAAGGACT1021CGGCGCGCCG GAAGTGGCCA GGGCGGGGGC GACTTCGGCT CACAGCGCGC CCGGCTATTC1081TCGCAGCTCA CCATGGATGA TGATATCGCC GCGCTCGTCG TCGACAACGG CTCCGGCATG1141TGCAAGGCCG GCTTCCCGGG CCACGATGCC CCCCGGGCCG TCTTCCCCTC CATCGTGGGG1201CGCCCCAGGC ACCAGGTAGG GGAGCTGGCT GGGTGGGGCA GCCCCGGGAG CCGGCGGGAG1261GCAAGGGCGC TTTCTCTGCA CAGGAGGCTG CCGGTTTCCG GGGTGGGCTG CGCCCGTGCT1321CAGGGCTTCT TGTCCTTTCC TTCCCAGGGC GTGATGGTGG GCATGGGTCA GAAGGATTCC1381TATGTGGGCG ACGAGGCCCA GAGCAAGAGA GGCATCCTCA CCCTGAAGTA CCCCATCGAG1441CACGCCATGG TCACCAACTG GGACGACATG GAGAAAATCT GGCACCACAC CTTCTACAAT1501GAGCTGCGTG TGGCTCCCGA GGAGCACCCC GTGCTGCTGA CCGAGGCCCC CCTGAACCCC1561AAGGCCAACC GCGAGAAGAT GACCCAGGTG AGTGGCCCGC TACCTCTTCT GGTGGCCGCC1621TCCCTCCTTC CTGGCCTCCC GGAGCTGCGC CCTTTCTCAC TGGTTCTCTC TTCTGCCGTT1681TTCCGTAGGA CTCTCTTCTC TGACCTGAGT CTCCTTTGGA ACTCTGCAGG TTCTATTTGC1741TTTTTCCCAG ATGAGCTCTT TTTCTGGTGT TTGTCTCTCT GACTAGGTGT CTGAGACAGT1801GTTGTGGGTG TAGGTACTAA CACTGGCTCG TGTGACAAGG CCATGAGGCT GGTGTAAAGC1861GGCCTTGGAG TGTGTATTAA GTAGGCGCAC AGTAGGTCTG AACAGACTCC CCATCCCAAG1921ACCCCAGCAC ACTTAGCCGT GTTCTTTGCA CTTTCTGCAT GTCCCCCGTC TGGCCTGGCT1981GTCCCCAGTG GCTTCCCCAG TGTGACATGG TGCATCTCTG CCTTACAGAT CATGTTTGAG2041ACCTTCAACA CCCCAGCCAT GTACGTTGCT ATCCAGGCTG TGCTATCCCT GTACGCCTCT2101GGCCGTACCA CTGGCATCGT GATGGACTCC GGTGACGGGG TCACCCACAC TGTGCCCATC2161TACGAGGGGT ATGCCCTCCC CCATGCCATC CTGCGTCTGG ACCTGGCTGG CCGGGACCTG2221ACTGACTACC TCATGAAGAT CCTCACCGAG CGCGGCTACA GCTTCACCAC CACGGCCGAG2281CGGGAAATCG TGCGTGACAT TAAGGAGAAG CTGTGCTACG TCGCCCTGGA CTTCGAGCAA2341GAGATGGCCA CGGCTGCTTC CAGCTCCTCC CTGGAGAAGA GCTACGAGCT GCCTGACGGC2401CAGGTCATCA CCATTGGCAA TGAGCGGTTC CGCTGCCCTG AGGCACTCTT CCAGCCTTCC2461TTCCTGGGTG AGTGGAGACT GTCTCCCGGC TCTGCCTGAC ATGAGGGTTA CCCCTCGGGG2521CTGTGCTGTG GAAGCTAAGT CCTGCCCTCA TTTCCCTCTC AGGCATGGAG TCCTGTGGCA2581TCCACGAAAC TACCTTCAAC TCCATCATGA AGTGTGACGT GGACATCCGC AAAGACCTGT2641ACGCCAACAC AGTGCTGTCT GGCGGCACCA CCATGTACCC TGGCATTGCC GACAGGATGC2701AGAAGGAGAT CACTGCCCTG GCACCCAGCA CAATGAAGAT CAAGGTGGGT GTCTTTCCTG2761CCTGAGCTGA CCTGGGCAGG TCAGCTGTGG GGTCCTGTGG TGTGTGGGGA GCTGTCACAT2821CCAGGGTCCT CACTGCCTGT CCCCTTCCCT CCTCAGATCA TTGCTCCTCC TGAGCGCAAG2881TACTCCGTGT GGATCGGCGG CTCCATCCTG GCCTCGCTGT CCACCTTCCA GCAGATGTGG2941ATCAGCAAGC AGGAGTATGA CGAGTCCGGC CCCTCCATCG TCCACCGCAA ATGCTTCTAG3001GCGGACTATG ACTTAGTTGC GTTACACCCT TTCTTGACAA AACCTAACTT GCGCAGAAAA3061CAAGATGAGA TTGGCATGGC TTTATTTGTT TTTTTTGTTT TGTTTTGGTT TTTTTTTTTT3121TTTTGGCTTG ACTCAGGATT TAAAAACTGG AACGGTGAAG GTGACAGCAG TCGGTTGGAG3181CGAGCATCCC CCAAAGTTCA CAATGTGGCC GAGGACTTTG ATTGCATTGT TGTTTTTTTA3241ATAGTCATTC CAAATATGAG ATGCATTGTT ACAGGAAGTC CCTTGCCATC CTAAAAGCCA3301CCCCACTTCT CTCTAAGGAG AATGGCCCAG TCCTCTCCCA AGTCCACACA GGGGAGGTGA3361TAGCATTGCT TTCGTGTAAA TTATGTAATG CAAAATTTTT TTAATCTTCG CCTTAATACT3421TTTTTATTTT GTTTTATTTT GAATGATGAG CCTTCGTGCC CCCCCTTCCC CCTTTTTGTC3481CCCCAACTTG AGATGTATGA AGGCTTTTGG TCTCCCTGGG AGTGGGTGGA GGCAGCCAGG3541GCTTACCTGT ACACTGACTT GAGACCAGTT GAATAAAAGT GCACACCTTA AAAATGAGGC3601CAAGTGTGAC TTTGTGGTGT GGCTGGGTTG GGGGCAGCAG AGGGTGGENBANK ID: XM_042788.1DEFINITION HOMO SAPIENS ALDOLASE B, FRUCTOSE-BISPHOSPHATE (ALDOB), MRNA.VERSION XM_042788.1 GI:14738248CDS 126..1220/CODON_START=11AAAAACATGA TGAGAAGTCT ATAAAAATTG TGTGCTACCA AAGATCTGTC TTATTTGGCA61GCTGCTGCCT CACCCACAGC TTTTGATATC TAGGAGGACT CTTCTCTCCC AAACTACCTG121TCACCATGGC CCACCGATTT CCAGCCCTCA CCCAGGAGCA GAAGAAGGAG CTCTCAGAAA181TTGCCCAGAG CATTGTTGCC AATGGAAAGG GGATCCTGGC TGCAGATGAA TCTGTAGGTA241CCATGGGGAA CCGCCTGCAG AGGATCAAGG TGGAAAACAC TGAAGAGAAC CGCCGGCAGT301TCCGAGAAAT CCTCTTCTCT GTGGACACTT CCATCAACCA GAGCATCGGG GGTGTCATCC361TTTTCCACGA GACCCTCTAC CAGAAAGACA GCCAGGGAAA GCTGTTCACA AACATCCTCA421AGGAAAAGGG GATCGTGGAG CGAATCAAGT TAGACCAAGG AGGTGCTCCT CTTGCAGGAA481CAAACAAAGA AACCACCATT CAAGGGCTTG ATGGCCTCTC AGAGCGCTGT GCTCACTACA541AGAAAGATGG TGTTGACTTT GGGAAGTGGC GTGCTGTGCT GAGGATTGCC GACCAGTGTC601CATCCAGCCT CGCTATCCAG CAAAACGCCA ACGCCCTGGC TCGCTACGCC AGCATCTGTC661AGCAGAATGG ACTGGTACCT ATTGTTGAAC CAGAGGTAAT TCCTGATGGA GACCATGACC721TGGAACACTG CCAGTATGTT ACTGAGAAGG TCCTGGCTGC TGTCTACAAG GCCCTGAATG781ACCATCATGT TTACCTGGAG GGCACCCTGC TAAAGCCCAA CATGGTGACT GCTGGACATG841CCTGCACCAA GAAGTATACT CCAGAACAAG TAGGTATGGC CACCGTAACA GCTCTCCACC901GTACTGTTCC TGCAGCTGTT CCTGGCATCT GCTTTTTGTC TGGTGGCATG AGTGAAGAGG961ATGCCACTCT CAACCTCAAT GCTATCAACC TTTGCCCTCT ACCAAAGCCC TGGAAACTAA1021GTTTCTCTTA TGGACGGGCC CTGCAGGCCA GTGCACTGGC TGCCTGGGGT GGCAAGGCTG1081CAAACAAGGA GGCAACCCAG GAGGCTTTTA TGAAGCGGGC CATGGCTAAC TGCCAGGCGG1141CCAAAGGACA GTATGTTCAC ACGGGTTCTT CTGGCGCTGC TTCCACCCAG TCCCTCTTCA1201CAGGCTGCTA TACCTACTAC GGTCCAATGC CCGCCAGCCT ACCTCCAGTG CTTCTACTAG1261GAGGGCTGAA AGGGAGCAAC TTTTCCTCCA ATCCTGGAAA TTCGACACAA TTAGATTTGA1321ACTGCTGGAA ATACAACACA TGTTAAATCT TAAGTACAAG GCGGAAAAAA TAAATCAGTT1381ATTGAAACAT AAAAATGAAT ACCAAGGACC TGATCAAATT TCACACAGCA GTTTCCTTGC1441AACACTTTCA GCTCCCCATG CTCCAGAATA CCCACCCAAG AAAATAATAG GCTTTAAAAC1501AATATCGGCT CCTCATCCAA AGAACAACTG CTGATTGAAA CACCTCATTA GCTGAGTGTA1561GAGAAGTGCA TCTTATGAAA CAGTCTTAGC AGTGGTAGGT TGGGAAGGAG ATAGCTCCAA1621CCAAAAAAGA AATAAATATT CTATAAACCT TCGENBANK ID: NM_005317.2DEFINITION HOMO SAPIENS GRANZYME N (LYMPHOCYTE MET-ASE 1) (GZMM), MRNA.VERSION NM_005317.2 GI:7108347CDS 46..819/CODON_START=11GGCTCGGGGC CGGGGCCAGC ACCCACACTG GGTCTCCACA GCGGCATGGA GGCCTGCGTG61TCTTCACTGC TGGTGCTGGC CCTGGGGGCC CTGTCAGTAG GCAGCTCCTT TGGGACCCAG121ATCATCGGGG GCCGGGAGGT GATCCCCCAC TCGCGCCCGT ACATGGCCTC ACTGCAGAGA181AATGGCTCCC ACCTGTGCGG GGGTGTCCTG GTGCACCCAA AGTGGGTGCT GACGGCTGCC241CACTGCCTGG CCCAGCGGAT GGCCCAGCTG AGGCTGGTGC TGGGGCTCCA CACGCTGGAC301AGCCCCGGTC TCACCTTCCA CATCAAGGCA GCCATCCAGC ACCGTGGCTA CAAGCCCGTC361CCTGCCCTGG AGAACGACCT CGCGCTGCTT CAGCTGGACG GGAAAGTGAA GCCCAGCCGG421ACCATCCGGC CGTTGGCCCT GCCCAGTAAG CGCCAGGTGG TGGCAGCAGG GACTCGGTGC481AGGATGCCGG GCTGGGGGCT GACCGACCAG GGCGGGCGCC TGTCCCGGGT GCTGCGGGAG541CTGGACCTCC AAGTGCTGGA CACCCGCATG TGTAACAACA GCCGCTTCTG GAACGGCAGC601CTCTCCCCCA GCATGGTCTG CCTGGCGGGC GACTCCAAGG ACCAGGCTCC CTGCAAGGGT661GACTCGGGCG GGCCCCTGGT GTGTGGCAAA GGCCGGGTGT TGGCCGGAGT CCTGTCCTTC721AGCTCCAGGG TCTGCACTGA CATCTTCAAG CCTCCCGTGG CCACCGCTGT GGCGCCTTAC781GTGTCCTGGA TCAGGAAGGT CACCGGCCGA TCGGCCTGAT GCCCTGGGGT GATGGGGACC841CCCTCGCTGT CTCCACAGGA CCCTTCCCCT CCAGGGGTGC AGTGGGGTGG GTGAGGACGG901GTGGGAGGGA CAGGGAGGGA CCAATAAATC ATAATGAAGA AACGCTCGENBANK ID: XM_003595.2DEFINITION HOMO SAPIENS GLOTAMYL AMINOPEPTIDASE (ANINOPEPTIDASE A)(ENPEP) ,MRNA.VERSION XM_003595.2 GI:13647140CDS 1401..2957/CODON_START=11TCCAATTTAA AAAGGAAGTC TGCTGACGTT AGTTAGTTAA ATTTAACATC TTTTTATGTG61TAACACTTGA CTTTGGAAGC AAAAATGAAC TTTGCGGAGA GAGAGGGCTC TAAGAGATAC121TGCATTCAAA CGAAACATGT GGCCATTCTC TGTGCGGTGG TGGTGGGTGT AGGATTAATA181GTGGGACTTG CCGTGGGCTT GACCAGATGG TGTGACTCCA GCGGGGACGG CGGGCCGGGC241ACTGCGCCAG CTCCTTCCCA CCTGCCTTCT TCCACGGCCA GCCCCTCAGG TCCTCCTGCC301CAGGACCAGG ACATCTGCCC GGCCAGTGAG GATGAGAGCG GACAGTGGAA AAACTTTCGA361CTGCCGGACT TCGTCAACCC AGTCCACTAC GACCTGCACG TGAAGCCCCT GTTGGAGGAG421GACACGTACA CGGGCACCGT GAGGATGTGC ATCAACCTGA GCGCTGCCAC CCGGTACCTG481TGGCTGCACC TCCGGGAGAC CAGGATGACG CGGCTCCCGG AGCTGAAGAG GCCCTCTGGG541GACCAGGTGC AAGTCCGGAG GTGTTTCGAG TACAAAAAGC AGGAGTACGT GGTGGTCGAG601GCGGAGGAAG AGCTTACCCC CAGCAGTGGA GATGGCCTGT ATCTCCTGAC CATGGAGTTC661GCCGGCTGGC TGAACGGCTC CCTCGAGGGA TTTTATAGAA CCACCTACAC GGAGAACGGA721CAAGTCAACA GCATAGTGGC CACCGATCAT GAACCAACAG ATCCCAGGAA ATCTTTTCCT781TGTTTTGATG AGCCCAACAA AAAGGCAACT TATACAATAT CTATCACCCA TCCCAAAGAA841TACGGACCAC TTTCAAATAT GCCAGTGGCG AAACAACAGT CAGTGGATGA TAAATGGACT901CGAACAACTT TTGAGAAGTC TGTCCCCATG AGCACGTACC TGGTGTGCTT TGCTGTACAT961CAATTTGACT CTGTAAAGAG AATATCAAAT AGTGGAAAAC CTCTTACAAT TTATGTCCAC1021CCAGAGCAAA AGCACACAGC CGAATATGCT GCAAACATAA CTAAAAGTGT GTTTGATTAT1081TTTGAAGAAT ACTTTGCTAT GAATTATTCT CTTCCTAAAT TAGATAAAAT CGCTATTCCA1141GATTTTGGCA CTGGTGCCAT GGAGAACTGG CGACTCATCA CGTACAGAGA AACGAACCTG1201CTTTATGACC CTAAGGAATC AGCCTCATCA AACCAACAGA GGGTGGCCAC TGTGGTTGCC1261CATGAACTTG TGCATCAGTG GTTTCGAAAT ATTGTGACCA TGGACTGGTG GGAAGACTTG1321TGCCTAAATG AAGGATTTGC TTCTTTCTTT GAGTTTCTGG GAGTAAACCA TGCAGAAACA1381GACTGGCAAA TGGTGACCAA ATGTTACTTG AAGATGTATT ACCTGTTCAA GAGGATGATT1441CTTTGATGTC TTCCCATCCA ATTATTGTGA CTGTGACAAC CCCTGATGAA ATAACATCTC1501TTTTTGATGG AATATCCTAT AGCAAGGGAT CTTCTATTTT GAGAATGCTT GAAGACTGGA1561TAAAACCAGA GAATTTTCAA AAAGGATGTC AGATGTACTT GGAAAAATAC CAATTCAAGA1621ATGCAAAAAC TTCTGATTTT TGGGCAGCAC TGGAAGAGGC AAGTAGGCTA CCAGTGAAAG1681AAGTAATGGA CACCTGCACC AGACAGATGG CTTATCCTGT GCTTAACGTG AACGGTGTCA1741AGAACATCAC ACAGAAACGC TTTTTGTTGC ACCCAAGAGC TAACCCTTCT CAGCCCCCTT1801CAGATCTTCG TTATACATGG AATATCCCAG TTAAATGGAC TGAAGATAAT ATAACAAGCA1861GTCTGTTATT TAATAGGTCA GAAAAAGAAG GAATGACTTT GAACTCCTCT AATCCTAGTG1921GAAATGCTTT TCTCAAAATA AACCCACATC ATATTGGGTT TTATCGTGTA AATTATGAAG1981TAGCAACTTG GGACTCGATA CCTACAGCGC TCTCCTTGAA CCACAAGACA TTTTCTTCAG2041CAGATCGTCC AAGTCTTATT GATGATGCTT TTGCCTTGGC AAGAGCTCAA CTTCTACATT2101ATAAGGTGGC TTTGAACTTG ACCAAGTATC TCAAAACGGA AGAGAATTTT TTACCATGGC2161AGAGAGTAAT TTCAGCTGTA ACCTACATCA TTAGCATGTT TGAAGATGAT AAAGAGCTAT2221ATCCTATGAT TGAGGAATAC TTCCAAGGTC AAGTGAAGCC TATTGCAGAT TCTCTGGGAT2281GGAATGATGC TGGAGACCAT GTCACAAAGT TACTCCGTTC CTCCGTGTTA GGGTTTGCGT2341GCAAGATGGG AGACAGAGAA GCCTTGAACA ATGCTTCCTC GTTATTTGAG CAGTGGCTAA2401ATGCCACTGT AAGCCTTCCC GTAAATCTCA GGCTTCTGGT GTATCGGTAT GGGATGCAGA2461ACTCTGGCAA TGAGATTTCA TGGAACTACA CTCTTGAGCA ATACCAGAAA ACTTCATTAG2521CTCAAGAAAA AGAAAAACTG CTGTATGGAT TAGCATCAGT GAAGAACGTT ACTCTTTTGT2581CAAGGTATTT GGATTTGCTC AAGGACACGA ACCTTATTAA AACTCAGGAT GTGTTTACAG2641TCATTCGATA TATCTCATAT AACAGCTATG GGAAGAACAT GGCCTGGAAT TGGATACAAC2701TCAACTGGCA CTATCTAGTC AACAGATATA CACTCAATAA CAGAAACGTT GGCCGAATTG2761TCACAATAGC AGAGCCATTC AACACTGAAC TGCAACTGTG GCAGATGGAG AGCTTTTTTG2821CAAAATATCC ACAAGCTGGA GCAGGAGAAA AACCTAGGGA ACAAGTGCTG GAAACAGTGA2881AAAACAATAT AGAGTGGCTA AAACAACATA GAAACACCAT CAGAGAATGG TTTTTTAATT2941TACTTGAGAG TGGTTAATGT ATTCAAATGT TAGAGTTTAA TTTTGTGAAT CTATTGTTTCGENBANK ID: U34683.1DEFINITION HUMAN GLUTATHIONE SYNTHETASE MRNA, COMPLETE CDS.VERSION 034683.1 GI:1236349CDS 41..1465/CODON_START=11GGGAGAACCG TTCGCGGAGG AAAGGCGAAC TAGTGTTGGG ATGGCCACCA ACTGGGGGAG61CCTCTTGCAG GATAAACAGC AGCTAGAGGA GCTGGCACGG CAGGCCGTGG ACCGGGCCCT121GGCTGAGGGA GTATTGCTGA GGACCTCACA GGAGCCCACT TCCTCGGAGG TGGTGAGCTA181TGCCCCATTC ACGCTCTTCC CCTCACTGGT CCCCAGTGCC CTGCTGGAGC AAGCCTATGC241TGTGCAGATG GACTTCAACC TGCTAGTGGA TGCTGTCAGC CAGAACGCTG CCTTCCTGGA301GCAAACTCTT TCCAGCACCA TCAAACAGGA TGACTTTACC GCTCGTCTCT TTGACATCCA361CAAGCAAGTC CTAAAAGAGG GCATTGCCCA GACTGTGTTC CTGGGCCTGA ATCGCTCAGA421CTACATGTTC CAGCGCAGCG CAGATGGCTC CCCAGCCCTG AAACAGATCG AAATCAACAC481CATCTCTGCC AGCTTTGGGG GCCTGGCCTC CCGGACCCCA GCTGTGCACC GACATGTTCT541CAGTGTCCTG AGTAAGACCA AAGAAGCTGG CAAGATCCTC TCTAATAATC CCAGCAAGGG601ACTGGCCCTG GGAATTGCCA AAGCCTGGGA GCTCTACGGC TCACCCAATG CTCTGGTGCT661ACTGATTGCT CAAGAGAAGG AAAGAAACAT ATTTGACCAG CGTGCCATAG AGAATGAGCT721ACTGGCCAGG AACATCCATG TGATCCGACG AACATTTGAA GATATCTCTG AAAAGGGGTC781TCTGGACCAA GACCGAAGGC TGTTTGTGGA TGGCCAGGAA ATTGCTGTGG TTTACTTCCG841GGATGGCTAC ATGCCTCGTC AGTACAGTCT ACAGAATTGG GAAGCACGTC TACTGCTGGA901GAGGTCACAT GCTGCCAAGT GCCCAGACAT TGCCACCCAG CTGGCTGGGA CTAAGAAGGT961GCAGCAGGAG CTAAGCAGGC CGGGCATGCT GGAGATGTTG CTCCCTGGCC AGCCTGAGGC1021TGTGGCCCGC CTCCGCGCCA CCTTTGCTGG CCTCTACTCA CTGGATGTGG GTGAAGAAGG1081GGACCAGGCC ATCGCCGAGG CCCTTGCTGC CCCTAGCCGG TTTGTGCTAA AGCCCCAGAG1141AGAGGGTGGA GGTAACAACC TATATGGGGA GGAAATGGTA CAGGCCCTGA AACAGCTGAA1201GCACACTGAG GAGAGGGCCT CCTACATCCT CATGGAGAAG ATCGAACCTG AGCCTTTTGA1261GAATTGCCTG CTACGGCCTG GCAGCCCTGC CCGAGTGGTC CAGTGCATTT CAGAGCTGGG1321CATCTTTGGG GTCTATGTCA GGCAGGAAAA GACACTCGTG ATGAACAAGC ACGTGGGGCA1381TCTACTTCGA ACCAAAGCCA TCGAGCATGC AGATGCTGGT GTGGCACCGG GAGTGGCAGT1441CCTGGACAAC CCATACCCTG TGTGAGGGCA CAACCAGGCC ACGGGACCTT CTATCCTCTG1501TATTTGTCAT TCCTCTCCTA GCCCTCCTGA GGGGTATCCT CCTAAAGACC TCCAAAGTTT1561TTATGGAAGG GTAAATACTG CTACCTTCCC CCAGCTTTCC ATCTGACGAC CAGAAAACTT1621GTGTCTCCCT TACATGACAT CTAGACGCCC CCAAATCCTT CAGATGTGGG TATAGCTCAG1681GCTAAGCTGC TCTGAGGTAA AGGTCCATGA ACCCTGCCCC ACTCCTGTCA GCCCCTCATC1741AGCCTTTTCA CCAGGTTCCA GTCCCTGACT TGGGATAGCA CTCAGTGCTA CCACCAGGGC1801GAGTGGAGGG GCATAGCCTT TCCCTAATTC TGCCTTAAAT AAAACTGCAT TGCTGTGENBANK ID: AF035429.1DNA LINEARDEFINITION HOMO SAPIENS CYTOCHEOME OXIDASE SUBUNIT I (001) AND SUBUNIT II(CCII) PSEUDOGENES, COMPLETE SEQUENCE.VERSION AF035429.1 GI:26657241AATATGAAAA TCACCTCGGA GCTGGTAAAA AGAGGCTTAA CCCCTGTCTT TAGATTTACA61GTCCAATGCT TCACTCAGCC ATTTTACCTC ACCCCCACTG ATGTTCGCCG ACCGTTGACT121ATTCTCTACA AACCACAAAG ACATTGGAAC ACTATACCTA TTATTCGGCG CATGAGCTGG181AGTCCTACGC ACAGCTCTAA GCCTCCTTAT TCGAGCCGAA CTGGGCCAGC CAGGCAACCT241TCTAGGTAAC GACCACATCT ACAACGTTAT CGTCACAGCC CATGCATTTG TAATAATCTT301CTTCATAGTA ATACCCATCA TAATCGGAGG CTTTGGCAAC TGACTAGTTC CCCTAATAAT361CGGTCCCCCC GATATGGCGT TTCCCCGCAT AAACAACATA AGCTTCTCAC TCTTACCCCC421CTCTCTCCTA CTCCTGCTTG CATCTCCTAT AGTGGAGGCC GGCGCAGGAA CAGGTTGAAC481AGTCTACCCT CCCTTGGCAG GGAACTACTC CCACCCTGGA GGCTGCGTAG ACCTAACCAT541CTTCTCCTTA CACCTAGCAG GTATCTCCTC TATCTTAGGA GCCATCAATT TCATCACAAC601AATTATTAAT ATAAAACCCC CTGCCATAAC CCAATACCAA ACGCCCCTTT TCGTCTGATC661CGTCCTAATC ACAGCAGTCT TACTTCTCCT ATCTCTCCCA GTCCTAGCCG CTGGCATCAC721TATACTACTA ACAGACCGTA ACCTCAACAC CACCTTCTTC GACCCAGCCG GAGGAGGAGA781CCCCATTCTA TACCAACACC TATTCTGATT TTTCGGTCAC CCTGAAGTTT ATATTGTGAT841CCTACCAGGC TTCGGAATAA TCTCCCATAT TGTAACTTAC TACTCCGGAA AAAAAGAACC801ATTTGGATAC ATAGGTATGG TCTGAGCTAT GATATCAATT GGCTTCCTAG GGTTTATCGT961GTGAGCACAC CATATATTTA CAGTAGGAAT AGACGTAGAC ACACGAGCAT ATTTCACCTC1021CGCTACCATA ATCATCGCTA TCCCCACCGG CGTCAAAGTA TTTAGCTGAC TCGCCACACT1081CCACGGAAGC AATATGAAAT GATCTGCTGC AGTGCTCTGA GCCCTAGGAT TTATTTTTCT1141TTTGACCGTA GGTGGGCTGA CTGGCATTGT ATTAGCAAAC TCATCACTAG ACATCGTACT1201ACACGACACG TACTACGTTG TAGCCCACTT CCACTATGTC CTATCAATAG GAGCTGTATT1261TGCCATCATA GGAGGCTTCA TTCACTGATT TCCCCTATTC TCAGGCTACA CCCTAGACCA1321AACCTACGCC AAAATCCATT TCGCTATCAT ATTCATCGGC GTAAATCTAA CTTTCTTCCC1381ACAACACTTT CTCGGCCTAT CCGGAATGCC CCGACGTTAC TCGGACTATC CCGATGCATA1441CACCACATGA AATATCCTAT CATCTGTAGG CTCATTCATT TCTCTAACAG CAGTAATATT1501AATAATTTTC ATAATTTGAG AAGCCTTCGC TTCGAAGCGA AAAGTCCTAA TAGTAGAAGA1561ACCCTCCATA AACCTGGAGT GACTATATGG ATGCCCCCCA CGCTACCACA CATTCGAAGA1621ACCCGTATAC ATAAAATCTA GACAAAAAAG GAAGGAATCG AACCCCCCAA AGCTGGTTTC1681AAGCCAACCC CATGGCCTCC ATGACTTTTT CAAAAAGATA TTAGAAAAAC CATTTCATAA1741CTTTGTCAAA GTTAAATTAT AGGCTAAATC CTATATATCT TAATGGCACA TGCAGCGCAA1801GTAGGTCTAC AAAACGCTAC TTCCCCTATC ATAGAAGAGC TTATCATCTT TCATGATCAC1861GCCCTCATAA TCATTTTCCT TATCTGCTTC CTAGTCCTGT ACGCCCTTTT CCTAACACTC1921ACAACAAAAC TAACTAATAC TAACATCTCA GACGCTCAGG AAATAGAAAC CGTCTGAACT1981ATCCTGCCCG CCATCATCCT AGTCCTTATC GGGCTGCCAT CCCTACGCAT CCTTTACATA2041ACAGACGAGG TCAACGATCC CTCCTTTACC ATCAAATCAA TTGGCCATCA ATGGTACTGA2101ACCTACGAAT ACACGGACTA CGGCGGACTA ATCTTCAACT CCTACATACT TCCCCCATTA2161TTCCTAGAAC CAGGCGACCT GCGACTCCTT GACGTTGACA ATCGAGTAGT ACTCCCGGTT2221GAAGCCCCCA TTCGTATAAT AATTACATCA CAAGACGTCT TACACTCATG AGCTGTCCCC2281ACATTAGGCT TAAAAACAGA TGCAATTCCC GGACGTCTAA ACCAAACCAC TTTCACTGCT2341ACACGACCAG GGGTATACTA CGGCCAATGC TCTGAAATCT GTGGAGCAAA CCAGTTTTAT2401GCCCATCGTC CTAGAATTAA TTCCCCTAAA AATCTTTGAA ATAGGGCCTG TATTTACCCT2461ATAGCACCCC CTCTACCCCC TCTAGAGCCC ACTGTAAAGC TAACTTAGCA TTAACCTTTT2521AAGTTAAAGA TTAAGAGAAC CAACACCTCT TTACAGTGAA ATGCCCCAAC TAAATACTAGENBANK ID: NM_024409.1DEFINITION HOMO SAPIENS NATRIURETIC PEPTIDE PRECURSOR C (NPPC), MRNA.VERSION NM_024409.1 GI:13249345CDS 1..381/CODON_START=11ATGCATCTCT CCCAGCTGCT GGCCTGCGCC CTGCTGCTCA CGCTGCTCTC CCTCCGGCCC61TCCGAAGCCA AGCCCGGGGC GCCGCCGAAG GTCCCGCGAA CCCCGCCGGC AGAGGAGCTG121GCCGAGCCGC AGGCTGCGGG CGGCGGTCAG AAGAAGGGCG ACAAGGCTCC CGGGGGCGGG181GGCGCCAATC TCAAGGGCGA CCGGTCGCGA CTGCTCCGGG ACCTGCGCGT GGACACCAAG241TCGCGGGCAG CGTGGGCTCG CCTTCTGCAA GACCACCGCA ACGCGCGCAA ATACAARGGA301GCCAACAAGA AGGGCTTGTC CAAGGGCTGC TTCGGCCTCA AGCTGGACCG AATCGGCTCC361ATGAGCGGCC TGGGATGTTA GGENBANK ID: M37763.1DNA LINEARDEFINITION HUMAN NEUROTROFHIN-3 (NT-3) GENE, COMPLETE CDS.VERSION M37763.1 GI:189300CDS 76..849/CODON_START=1GENE 76..849MAT PEPTIDE 130..8461TAACACAGAC TCAGCTGCCA GAGCCTGCTC TTAACACCTG TGTTTCCTTT TCAGATCTTA61CAGGTGAACA AGGTGATGTC CATCTTGTTT TATGTGATAT TTCTCGCTTA TCTCCGTGGC121ATCCAAGGTA ACAACATGGA TCAAAGGAGT TTGCCAGAAG ACTCGCTCAA TTCCCTCATT181ATTAAGCTGA TGCAGGCAGA TATTTTGAAA AACAAGCTCT CCAAGCAGAT GGTGGACGTT241AAGGAAAATT ACCAGAGCAC CCTGCCCAAA GCTGAGGCTC CCCGAGAGCC GGAGCGGGGA301GGGCCCGCCA AGTCAGCATT CCAGCCGGTG ATTGCAATGG ACACCGAACT GCTGCGACAA361CAGAGACGCT ACAACTCACC GCGGGTCCTG CTGAGCGACA GCACCCCCTT GGAGCCCCCG421CCCTTGTATC TCATGGAGGA TTACGTGGGC AGCCCCGTGG TGGCGAACAG ARCATCACGG481CGGAAACGGT ACGCGGAGCA TAAGAGTCAC CGAGGGGAGT ACTCGGTATG TGACAGTGAG541AGTCTGTGGG TGACCGACAA GTCATCGGCC ATCGACATTC GGGGACACCA GGTCACGGTG601CTGGGGGAGA TCAAAACGGG CAACTCTCCC GTCAAACAAT ATTTTTATGA AACGCGATGT661AAGGAAGCCA GGCCGGTCAA AAACGGTTGC AGGGGTATTG ATGATAAACA CTGGAACTCT721CAGTGCAAAA CATCCCAAAC CTACGTCCGA GCACTGACTT CAGAGAACAA TAAACTCGTG781GGCTGGCGGT GGATACGGAT AGACACGTCC TGTGTGTGTG CCTTGTCGAG AAAAATCGGA841AGAACATGAA TTGGCATCTC TCCCCATATA TAAATTATTA CTTTAAATTA TATGATATGC901ATGTAGCATA TAAATGTTTA TATTGTTTTT ATATATTATA AGTTGACCTT TATTTATTAA961ACTTCAGCAA CCCTACAGTA TATAAGCTTT TTTCTCAATA AAATCAGTGT GCTTGCCTTCGENBANK ID: NM_000932.1DEFINITION HOMO SAPIENS PHOSPHOLIPASE C, BETA 3(PHOSPHATIDYLINOSITOL-SPECIFIC) (PLCB3), MRNA.VERSION NM_000932.1 GI:11386138CDS 1..37051ATGGCGGGCG CCCAGCCCGG CGTCCACGCG CTGCAGTTGG AGCCGCCCAC CGTGGTGGAG61ACCCTGCGGC GCGGGAGTAA GTTCATCAAA TGGGACGAGG AGACCTCCAG TCGGAACCTG121GTGACCCTGC GTGTGGACCC CAATGGCTTC TTCTTGTACT GGACGGGCCC CAACATGGAG181GTGGACACAC TGGACATCAG TTCCATCAGG GACACACGGA CAGGCCGGTA CGCCCGCCTG241CCCAAGGACC CCAAGATCCG GGAAGTTCTG GGCTTTGGGG GTCCCGATGC CCGGCTGGAG301GAGAAGCTGA TGACGGTGGT GTCTGGGCCA GACCCGGTGA ACACAGTGTT CTTGAACTTC361ATGGCCGTGC AGGATGACAC AGCCAAGGTC TGGTCTGAGG AGCTATTCAA GCTGGCTATG421AACATCCTGG CTCAGAACGC CTCCCGGAAC ACCTTCCTGC GCAAAGCATA CACGAAGCTG481AAGCTGCAGG TGAACCAGGA TGGTCGGATC CCCGTCAAGA ACATCCTGAA GATGTTCTCA541GCAGACAAGA AGCGGGTGGA GACTGCGCTG GAATCCTGTG GCCTCAAATT CAACCGGAGT601GAGTCCATCC GGCCTGATGA GTTTTCCTTG GAAATCTTTG AGCGGTTCCT GAACAAGCTG661TGTCTGCGGC CGGACATTGA CAAGATCCTG CTGGAGATAG GCGCCAAGGG CAAGCCATAC721CTGACGCTGG AGCAGCTCAT GGACTTCATC AACCAGAAGC AACGCGACCC GAGACTCAAC781GAAGTGCTGT ACCCGCCCCT GCGGCCCTCC CAGGCCCGGC TGCTCATCGA AAAGTATGAG841CCCAACCAGC AGTTTCTGGA GCGAGACCAG ATGTCCATGG AGGGCTTTAG CCGCTACCTG901GGAGGCGAGG AGAATGGCAT CCTGCCCCTG GAAGCCCTGG ATCTGAGCAC GGACATGACC961CAGCCACTGA GTGCCTACTT CATCAACTCC TCGCATAACA CCTATCTCAC TGCGGGGCAG1021CTGGCTGGGA CCTCGTCGGT GGAGATGTAC CGCCAGGCAC TACTATGGGG CTGCCGCTGC1081GTGGAGCTGG ACGTGTGGAA GGGACGGCCG CCTGAGGAGG AACCCTTCAT TACCCACGGC1141TTCACCATGA CCACAGAGGT GCCTCTGCGC GACGTGCTGG AGGCCATTGC CGAGACTGCC1201TTCAAGACCT CGCCCTACCC CGTCATCCTC TCCTTCGAGA ACCATGTGGA CTCGGCAAAG1261CAACAGGCAA AGATGGCTGA GTACTGCCGC TCCATCTTTG GAGACGCGCT ACTCATCGAG1321CCTCTGGACA AGTACCCGCT GGCCCCAGGC GTTCCCCTGC CCAGCCCCCA GGACCTGATG1381GGCCGTATCC TGGTGAAGAA CAAGAAGCCG CACCGACGCA GCGCAGGTGG CCCAGACAGC1441GCCGGGCGCA AGCGGCCCCT GGAGCAGAGC AATTCTGCCC TGAGCGAGAG CTCCGCGGCC1501ACCGAGCCCT CCTCCCCGCA GCTGCGGTCT CCCAGCTCTG ACAGCTGCCC AGGCCTGAGC1561AATGGGGAGG AGGTAGGCCT TCACAAGCCC ACCCTGCAGC CTCAGAAGTC TCTCGGTGAC1621GAGCGCCTGA ACCGAGGCCC CTATGTTCTT GGACCTGCTG ACCGTGAGGA TGAGGAGGAA1681GATGAGCAAG AGCAGGAACA GACAGACCCC AAAAAGCCAA CTACAGATGA GGGGACAGCC1741AGCAGCGAGG TGAATGCCAC TGAGGAGATG TCCACGCTTG TCAACTACAT CGAACCTGTC1801AAGTTCAAGT CCTTTGAGGC TGCTCGAAAG AGGAACAAAT GCTTCGAGAT GTCGTCCTTT1861GTGGAGACCA AGGCCATGGA GCAACTGACC AAGAGCCCCA TGGAGTTTGT GGAATACAAC1921AAGCAGCAGC TCAGCCGCAT CTACCCCAAG GGCACCCGCG TGGACTCCTC CAACTACATG1981CCCCAGCTCT TCTGGAACGT AGGGTGCCAG CTTGTTGCGC TCAACTTCCA GACCCTCGAT2041GTGGCGATGC AGCTCAACGC GGGCGTTTTT GAGTACAACG GGCGCAGCGG GTACCTGCTC2101AAGCCGGAGT TCATGCGGCG GCCGGACAAG TCCTTCGACC CCTTCACTGA GGTCATCGTG2161GATGGCATCG TGGCCAATGC CTTGCGGGTC AAGGTGATCT CAGGGCAGTT CCTGTCCGAC2221AGGAAGGTGG GCATCTACGT GGAGGTGGAC ATGTTTGGCC TCCCTGTTGA TACGCGGCGC2281AAGTACCGCA CCCGGACCTC TCAGGGGAAC TCGTTCAACC CCGTGTGGGA CGAAGAGCCC2341TTCGACTTCC CCAAGGTGGT GCTGCCCACG CTGGCTTCAC TTCGCATTGC AGCCTTTGAG2401GAGGGGGGTA AATTCGTAGG GCACCGGATC CTGCCTGTCT CTGCCATCCG CTCCGGATAC2461CACTACGTGT GCCTGCGGAA CGAGGCCAAC CAACCGCTGT GCCTGCCGGC CCTGCTCATC2521TACACCGAAG CCTCGGACTA CATTCCTGAC GACCACCAGG ACTATGCGGA GGCCCTGATC2581AACCCCATTA AGCACGTCAG CCTGATGGAC CAGAGGGCCC GGCAGCTGGC CGCCCTCATT2641GGGGAGAGTG AGGGTGAGGC TGGCCAAGAG ACGTGCCAGG ACACCCAGTC TCAGCAGCTG2701GGGTCTCAGC CGTCCTCAAA CCCCACCCCC AGCCCACTGG ATGCCTCCCC CCGCCGGCCC2761CCTGGCCCCA CCACCTCCCC TGCCAGCACC TCCCTCAGCA GCCCAGGGCA GCGTGATGAT2821CTCATCGCCA GCATCCTCTC AGAGGTGGCC CCCACCCCGC TGGATGAGCT CCGAGGTCAC2881AAGGCTCTGG TCAAGCTCCG GAGCCGGCAA GAGCGAGACC TGCGGGAGCT GCGCAAGAAG2941CATGAGGGGA AGGCAGTCAC CCTCACCCGC CGCCTGCTGG ATGGCCTGGC TCAGGCACAG3001GCTGAGGGCA GGTGCCGGCT GCGGCCAGGT GCCCTAGGTG GGGCCGCTGA TGTGGAGGAC3061ACGAAGGAGG GGGAGGACGA GGCAAAGCGG TATCAGGAGT TCCAGAACAG ACAGGTGCAG3121AGCCTGCTGG AGCTGCGGGA GGCCCAGGTG GACGCAGAGG CCCAGCGGAG GCTGGAACAC3181CTGAGACAGG CTCTGCAGCG GCTCAGGGAG GTCGTCCTTG ATGCAAACAC AACTCAGTTC3241AAGAGGCTGA AAGAGATGAA CGAGAGGGAG AAGAAGGAGC TGCAGAAGAT CCTGGACAGA3301AAGCGCCATA ACAGCATCTC GGAGGCCAAG ATGAGGGACA AGCATAAGAA GGAGGCGGAA3361CTGACGGAGA TTAACCGTCG GCACATCACT GAGTCAGTCA ACTCCATCCG TCGGCTGGAG3421GAGGCCCAGA AGCAGCGGCA TGACCGTCTT GTGGCTGGGC AGCAGCAGGT CCTGCAACAG3481CTGGCAGAAG AGGAGCCCAA GCTGCTGGCC CAGCTGGCCC AGGAGTGTCA GGAGCAGCGG3541GCGAGGCTCC CCCAGGAGAT CCGCCGGAGC CTGCTGGGCG AGATGCCGGA GGGGCTGGGG3601GACGGGCCTC TGGTGGCCTG TGCCAGCAAC GGTCACGCAC CCGGGAGCAG CGGGCACCTG3661TCGGGCGCTG ACTCGGAGAG CCAGGAGGAG AACACGCAGC TCTGAGENBANK ID: D13119.1DEFINITION HOMO SAPIENS P2 MRNA FOR ATP SYNTHASE SUBUNIT C, COMPLETE CDS.VERSION D13119.1 GI:285909CDS 31..456/CODON_START=11TCTCCTGCCA CAGCTCCTCA CCCCCTGAAA ATGTTCGCCT GCTCCAAGTT TGTCTCCACT61CCCTCCTTGG TCAAGAGCAC CTCACAGCTG CTGAGCCGTC CGCTATCTGC AGTGGTGCTG121AAACGACCGG AGATACTGAC AGATGAGAGC CTCAGCAGCT TGGCAGTCTC ATGTCCCCTT181ACCTCACTTG TCTCTAGCCG CAGCTTCCAA ACCAGCGCCA TTTCAAGGGA CATCGACACA241GCAGCCAAGT TCATTGGAGC TGGGGCTGCC ACAGTTGGGG TGGCTGGTTC TGGGGCTGGG301ATTGGAACTG TGTTTGGGAG CCTCATCATT GGTTATGCCA GGAACCCTTC TCTGAAGCAA361CAGCTCTTCT CCTACGCCAT TCTGGGCTTT GCCCTCTCGG AGGCCATGGG GCTCTTTTGT421CTGATGGTAG CCTTTCTCAT CCTCTTTGCC ATGTGAAGGA GCCGTCTCCA CCTCCCATAG481TTCTCCCGCG TCTGGTTGGC CCCGTGTGTT CCTTTTCCTA TACCTCCCCA GGCAGCCTGG541GGAACGTGGT TGGCTCAGGG TTTGACAGAG AAAAGACAAA TAAATACTGT ATTAATAAGGENBANK ID: NM_004530.1DEFINITION HOMO SAPIENS MATRIX METALLOPROTEINASE 2 (GELATINASE A, 72KDGELATINASE, 72KD TYPE IV COLLAGENASE) (MMP2), MRNA.VERSION NM_004530.1 GI:11342665CDS 290..2272/CODON_START=11TGTTTCCGCT GCATCCAGAC TTCCTCAGGC GGTGGCTGGA GGCTGCGCAT CTGGGGCTTT61AAACATACAA AGCGATTGCC AGGACCTGCG GCGGCGGCGG CGGCGGCGGG GGCTGGGGCG121CGGGGGCCGG ACCATGAGCC GCTCAGCCGG GCAAACCCCA GGCCACCGAG CCAGCGGACC181CTCGGAGCGC AGCCCTGCGC CGCGGACCAG GCTCCAACCA GGCGGCGAGG CGGCCACACG241CACCGAGCCA GCGACCCCCG GGCGACGCGC GGGGCCAGGG AGCGCTACGA TGGAGGCGCT301AATGGCCCGG GGCGCGCTCA CGCGTCCCCT GAGGGCGCTC TGTCTCCTGG GCTGCCTGCT361GAGCCACGCC GCCGCCGCGC CGTCGCCCAT CATCAAGTTC CCCGGCGATG TCGCCCCCAA421AACGGACAAA GAGTTGGCAG TGCAATACCT GAACACCTTC TATGGCTGCC CCAAGGAGAG481CTGCAACCTG TTTGTGCTGA AGGACACACT AAAGAAGATG CAGAAGTTCT TTGGACTGCC541GCAGACAGCT GATCTTGACC AGAATACCAT CGAGACCATG CGGAAGCCAC GCTGCGGCAA601CCCAGATGTG GCCAACTACA ACTTCTTCCC TCGCAAGCCC AAGTGGGACA AGAACCAGAT661CACATACAGG ATCATTGGCT ACACACCTGA TCTGGACCCA GAGACAGTGG ATGATGCCTT721TGCTCGTGCC TTCCAAGTCT GGAGCGATGT GACCCCACTG CGGTTTTCTC GAATCCATGA781TGGAGAGGCA GACATCATGA TCAACTTTCG CCGCTGGGAG CATGGCGATG GATACCCCTT841TGACGGTAAG GACGGACTCC TGGCTCATCC CTTCGCCCCA GGCACTGGTG TTGGGGGAGA901CTCCCATTTT GATGACGATG AGCTATGGAC CTTGGGAGAA GGCCAAGTGG TCCGTGTGAA961GTATGGCAAC GCCGATGGGG AGTACTGCAA GTTCCCCTTC TTGTTCAATG GCAAGGAGTA1021CAACAGCTGC ACTGATACTG GCCGCAGCGA TGGCTTCCTC TGGTCCTCCA CCACCTACAA1081CTTTGAGAAG GATGGCAAGT ACGGCTTCTG TCCCCATGAA GCCCTGTTCA CCATGGGCGG1141CAACGCTGAA GGACAGCCCT GCAAGTTTCC ATTCCGCTTC CAGGGCACAT CCTATGACAG1201CTGCACCACT GAGGGCCGCA CCGATGGCTA CCGCTGGTGC GGCACCACTG AGGACTACGA1261CCGCGACAAG AAGTATGGCT TCTGCCCTGA GACCGCCATG TCCACTGTTG GTGGGAACTC1321AGAAGGTGCC CCCTGTGTCT TCCCCTTCAC TTTCCTGGGC AACAAATATG AGAGCTGCAC1381CAGCGCCGGC CGCAGTGACG GAAAGATGTG GTGTGCGACC ACAGCCAACT ACGATGACGA1441CCGCAAGTGG GGCTTCTGCC CTGACCAAGG GTACAGCCTG TTCCTCGTGG CAGCCCACGA1501GTTTGGCCAC GCCATGGGGC TGCAGCACTC CCAAGACCCT GGGGCCCTGA TGGCACCCAT1561TTACACCTAC ACCAAGAACT TCCGTCTGTC CCAGGATGAC ATCAAGGGCA TTCAGGAGCT1621CTATGGGGCC TCTCCTGACA TTGACCTTGG CACCGGCCCC ACCCCCACAC TGGGCCCTGT1681CACTCCTGAG ATCTGCAAAC AGGACATTGT ATTTGATGGC ATCGCTCAGA TCCGTGGTGA1741GATCTTCTTC TTCAAGGACC GGTTCATTTG GCGGACTGTG ACGCCACGTG ACAAGCCCAT1801GGGGCCCCTG CTGGTGGCCA CATTCTGGCC TGAGCTCCCG GAAAAGATTG ATGCGGTATA1861CGAGGCCCCA CAGGAGGAGA AGGCTGTGTT CTTTGCAGGG AATGAATACT GGATCTACTC1921AGCCAGCACC CTGGAGCGAG GGTACCCCAA GCCACTGACC AGCCTGGGAC TGCCCCCTGA1981TGTCCAGCGA GTGGATGCCG CCTTTAACTG GAGCAAAAAC AAGAAGACAT ACATCTTTGC2041TGGAGACAAA TTCTGGAGAT ACAATGAGGT GAAGAAGAAA ATGGATCCTG GCTTTCCCAA2101GCTCATCGCA GATGCCTGGA ATGCCATCCC CGATAACCTG GATGCCGTCG TGGACCTGCA2161GGGCGGCGGT CACAGCTACT TCTTCAAGGG TGCCTATTAC CTGAAGCTGG AGAACCAAAG2221TCTGAAGAGC GTGAAGTTTG GAAGCATCAA ATCCGACTGG CTAGGCTGCT GAGCTGGCCC2281TGGCTCCCAC AGGCCCTTCC TCTCCACTGC CTTCGATACA CCGGGCCTGG AGAACTAGAG2341AAGGACCCGG AGGGGCCTGG CAGCCGTGCC TTCAGCTCTA CAGCTAATCA GCATTCTCAC2401TCCTACCTGG TAATTTAAGA TTCCAGAGAG TGGCTCCTCC CGGTGCCCAA GAATAGATGC2461TGACTGTACT CCTCCCAGGC GCCCCTTCCC CCTCCAATCC CACCAACCCT CAGAGCCACC2521CCTAAAGAGA TCCTTTGATA TTTTCAACGC AGCCCTGCTT TGGGCTGCCC TGGTGCTGCC2581ACACTTCAGG CTCTTCTCCT TTCACAACCT TCTGTGGCTC ACAGAACCCT TGGAGCCAAT2641GGAGACTGTC TCAAGAGGGC ACTGGTGGCC CGACAGCCTG GCACAGGGCA GTGGGACAGG2701GCATGGCCAG GTGGCCACTC CAGACCCCTG GCTTTTCACT GCTGGCTGCC TTAGAACCTT2761TCTTACATTA GCAGTTTGCT TTGTATGCAC TTTGTTTTTT TCTTTGGGTC TTGTTTTTTT2821TTTCCACTTA GAAATTGCAT TTCCTGACAG AAGGACTCAG GTTGTCTGAA GTCACTGCAC2881AGTGCATCTC AGCCCACATA GTGATGGTTC CCCTGTTCAC TCTACTTAGC ATGTCCCTAC2941CGAGTCTCTT CTCCACTGGA TGGAGGAAAA CCAAGCCGTG GCTTCCCGCT CAGCCCTCCC3001TGCCCCTCCC TTCAACCATT CCCCATGGGA AATGTCAACA AGTATGAATA AAGACACCTA3061CTGAGTGGCGENBANK ID: NN_000852.2DEFINITION HOMO SAPIENS GLUTATHIONE S-TRANSFERASE PI (GSTP1), MRNA.VERSION NM_000852.2 GI:6552334CDS 30..6621GGAGTTTCGC CGCCGCAGTC TTCGCCACCA TGCCGCCCTA CACCGTGGTC TATTTCCCAG61TTCGAGGCCG CTGCGCGGCC CTGCGCATGC TGCTGGCAGA TCAGGGCCAG AGCTGGAAGG121AGGAGGTGGT GACCGTGGAG ACGTGGCAGG AGGGCTCACT CAAAGCCTCC TGCCTATACG181GGCAGCTCCC CAAGTTCCAG GACGGAGACC TCACCCTGTA CCAGTCCAAT ACCATCCTGC241GTCACCTGGG CCGCACCCTT GGGCTCTATG GGAAGGACCA GCAGGAGGCA GCCCTGGTGG301ACATGGTGAA TGACGCCGTG GAGGACCTCC GCTGCAAATA CATCTCCCTC ATCTACACCA361ACTATGAGGC GGGCAAGGAT GACTATGTGA AGGCACTGCC CGGGCAACTG AAGCCTTTTG421AGACCCTGCT GTCCCAGAAC CAGGGAGGCA AGACCTTCAT TGTGGGAGAC CAGATCTCCT481TCGCTGACTA CAAGCTGCTG GACTTGCTGC TGATCCATGA GGTCCTAGCC CCTGGCTGCC541TGGATGCGTT CCCCCTGCTC TCAGCATATG TGGGCCGCCT CACCGCCCGG CCCAAGCTCA601AGGCCTTCCT GGCCTCCCCT CAGTACGTGA ACCTCCCCAT CAATGGCAAC GGGAAACAGT661GAGGGTTGGG GGGACTCTGA GCGGGAGGCA GAGTTTGCCT TCCTTTCTCC AGGACCAATA721AAATTTCTAA GAGAGCTGENBANK ID: XM_016524.4DEFINITION HOMO SAPIENS CREATINE KINASE, MITOCHONDRIAL 1 (UBIQUITOUS)(CENT1) ,MRNA.VERSION XM_016524.4 GI:17477504CDS 358..1704/CODON_START=11CGCGCGAGTC TCAGGTCCCG CTAATTACCT GGCGGGTGCT GCCCACCCCT GCCCTCGCGC61ACCTACCGCG GTGGCAGGCG GGAAGGCGGG GCCTGGGGGA GCCCCACCCC TGGAGACTGC121GGCTGGGGCC TCCCTCTCCT CCGCCCGCCC GCCTGCCACT AGCTCATTGC GCCTCTCCTG181CAGTCTGATT GGCACCGGCT CCCATTCCGG CTCCAGCCTC CAATCCGACC CCCATTTCGG241CTGCAGCCTC GGACCTAGCT CCGGCCCTCG GTCTATCCGG TTGCATCCTC CCTCCCTGTT301CCGGATCTTA TCTTGCGCCA GCGCCTACTC CAGGATCCCG TACCGAGACG TCAAGCCATG361GCTGGTCCCT TCTCCCGTCT GCTGTCCGCC CGCCGGGGAC TCAGGCTCCT GGCTTTGGCC421GGAGCGGGGT CTCTAGCCGC TGGGTTTCTG CTCCGACCGG AACCTGTACG AGCTGCCAGT481GAACGACGGA GGCTGTATCC CCCGAGCCAG ACATGGCCAA CTGGACAGCT CCCAGGTAAC541TGCACTAGGT CTAGGCGTCT GTGCCCTCCC TCCATGGTTA CTGGGTACCC CCTCCCCAGC601GCTGAGTACC CAGACCTCCG AAAGCACAAC AACTGCATGG CCAGTCACCT GACCCCAGCA661GTCTATGCAC GGCTCTGCGA CAAGACCACA CCCACTGGTT GGACGCTAGA TCAGTGTATC721CAGACTGGCG TGGACAACCC TGGCCACCCC TTCATCAAGA CTGTGGGCAT GGTGGCTGGA781GATGAGGAGA CCTATGAGGT ATTTGCTGAC CTGTTTGACC CTGTGATCCA AGAGGGACAC841AATGGATATG ACCCCCGGAC AATGAAGCAC ACCACGGATC TAGATGCCAG TAAAATCCGT901TCTGGCTACT TTGATGAGAG GTATGTATTG TCCTCTAGAG TCAGAACTGG CCGAAGCATC961CGAGGACTCA GTCTGCCTCC AGCTTGCACT CGAGCAGAGC GACGAGAGGT GGAACGTGTT1021GTGGTGGATG CACTGAGTGG CCTGAAGGGT GACCTGGCTG GACGTTACTA TAGGCTCAGT1081GAGATGACAG AGGCTGAACA GCAGCAGCTT ATTGATGACC ACTTTCTGTT TGATAAGCCT1141GTGTCCCCGT TGCTGACTGC AGCAGGAATG GCTCGAGACT GGCCAGATGC TCGTGGAATT1201TGGCACAACA ATGAGAAGAG CTTCCTGATC TGGGTGAATG AGGAGGATCA TACACGGGTG1261ATCTCCATGG AGAAGGGTGG TAACATGAAG AGAGTGTTTG AAAGATTCTG CCGAGGCCTC1321AAAGAGGTGG AGAGACTTAT CCAAGAACGT GGCTGGGAGT TCATGTGGAA TGAGCGTTTG1381GGATACATCT TGACCTGTCC ATCTAACCTG GGCACTGGAC TTCGGGCAGG AGTGCACATC1441AAACTGCCCC TGCTAAGCAA AGATAGCCGC TTCCCAAAGA TCCTGGAGAA CCTAAGACTC1501CAAAAACGTG GTACTGGAGG AGTGGACACT GCTGCTACAG GCGGTGTCTT TGATATTTCT1561AATTTGGACC GACTAGGCAA ATCAGAGGTG GAGCTGGTGC AACTGGTCAT CGATGGAGTA1621AACTATTTGA TTGATTGTGA ACGGCGTCTG GAGAGAGGUC AGGATATCCG CATCCCCACA1681CCTGTCATCC ACACCAAGCA TTAACTCCCC ATCGCCAGCT GATGACTCAA GATTCCCAGG1741AGTTCTGCTC ATTCTAATGA TGGCCCATTC TACTTGCTCT GGACCTGCCC CCGCATCCCC1801TGCCTCCATC CTAGTAAAGA CTCCTTGCTA TGCTGCGENBANK ID: NM_001443.1DEFINITION HOMO SAPIENS FATTY ACID BINDING PROTEIN 1, LIVER (FABP1),MRNA. VERSION NM_001443.1 GI:4557576CDS 43..4261AGAGCCGCAG GTCAGTCGTG AAGAGGGAGC TCTATTGCCA CCATGAGTTT CTCCGGCAAG61TACCAACTGC AGAGCCAGGA AAACTTTGAA GCCTTCATGA AGGCAATCGG TCTGCCGGAA121GAGCTCATCC AGAAGGGGAA GGATATCAAG GGGGTGTCGG AAATCGTGCA GAATGGGAAG181CACTTCAAGT TCACCATCAC CGCTGGGTCC AAAGTGATCC AAAACGAATT CACGGTGGGG241GAGGAATGTG AGCTGGAGAC AATGACAGGG GAGAAAGTCA AGACAGTGGT TCAGTTGGAA301GGTGACAATA AACTGGTGAC AACTTTCAAA AACATCAAGT CTGTGACCGA ACTCAACGGC361GACATAATCA CCAATACCAT GACATTGGGT GACATTGTCT TCAAGAGAAT CAGCAAGAGA421ATTTAAACAA GTCTGCATTT CATATTATTT TAGTGTGTAA AATTAATGTA ATAAAGTGAA481CTTTGTTTTGENBANK ID: NM_001220.1DEFINITION HOMO SAPIENS CALCIUMCALNODULINDEPENDENT PROTEIN KINASE (CANKINASE) II BETA (CZANK2B), MRNA.VERSION NM_001220.1 GI:10835005CDS 47..16751GCGGCCCGCG TCGACCGAGC GCACGCCCAG CCCCTCCGCC GCCGCCATGG CCACCACGGT61GACCTGCACC CGCTTCACCG ACGAGTACCA GCTCTACGAG GATATTGGCA AGGCGGCTTT121CTCTGTGGTC CGACGCTGTG TCAAGCTCTG CACCGGCCAT GACTATGCAG CCAAGATCAT181CAACACCAAG AAGCTGTCAG CCAGAGATCA CCAGAAGCTG GAGAGACAGG CTCGGATCTG241CCGCCTTGTG AAGCATTCCA ACATCGTGCG TCTCCACGAC AGCATCTCCG AGGAGGGCTT301CCACTACCTG GTCTTCGATC TGGTCACTGG TGGGGAGCTC TTTGAAGACA TTGTGGCGAG361AGAGTACTAC AGCGAGGCTG ATGCCAGTCA CTGTATCCAG CAGATCCTGK AGGCCGTTCT421CCATTGTCAC CAAATGGCCG TCCTCCACAG AGACCTCAAG CCGSAGAACC TGCTTCTGGC481CAGCAAGTGC AAAGGGGCTG CAGTGAAGCT GGCAGACTTC GGCCTAGCTA TCGAGGTGCA541GGGGGACCAG CAGGCATGGT TTGGTTTCGC TGGCACACCA GCCTACCTGT CCCCTGAGGT601CCTTCGCAAA GAGGCGTACG GCAAGCCCGT GGACATCTGG GCATGTGGGG TGATCCTGTA661CATCCTGCTC GTGGGCTACC CACCCTTCTG GGACGAGGAC CAGCACAAGC TGTACCAGCA721GATCAAGGCT GGTGCCTATG ACTTCCCGTC CCCTGAGTGG GACACCGTCA CTCCTGAAGC781CAAAAACCTC ATCAACCAGA TGCTGACCAT CAACCCTGCC AAGCGCATCA CAGCCCATGA841GGCCCTGAAG CACCCGTGGG TCTGCCAACG CTCCACGGTA GCATCCATGA TGCACAGACA901GGAGACTGTG GAGTGTCTGA AAAAGTTCAA TGCCAGGAGA AAGCTCAAGG GAGCCATCCT961CACCACCATG CTGGCCACAC GGAATTTCTC AGTGGGCAGA CAGACCACCG CTCCGGCCAC1021AATGTCCACC GCGGCCTCCG GCACCACCAT GGGGCTGGTG GAACAAGCCA AGAGTTTACT1081CAACAAGAAA GCAGATGGAG TCAAGCCCCA GACGAATAGT ACCAAAAACA GTGCAGCCGC1141CACCAGCCCC AAAGGGACGC TTCCTCCTGC CGCCCTGGAG CCTCAAACCA CCGTCATCCA1201TAACCCAGTG GACGGGATTA AGGAGTCTTC TGACAGTGCC AATACCACCA TAGAGGATGA1281AGACGCTAAA GCCCGGAAGC AGGAGATCAT TAAGACCACG GAGCAGCTCA TCGAGGCCGT1321CAACAACGGT GACTTTGAGG CCTACGCGAA AATCTGTGAC CCAGGGCTGA CCTCGTTTGA1381GCCTGAAGCA CTGGGCAACC TGGTTGAAGG GATGGACTTC CACAGATTCT ACTTCGAGAA1441CCTGCTGGCC AAGAACAGCA AGCCGATCCA CACGACCATC CTGAACCCAC ACGTGCACGT1501CATTGGAGAG GATGCCGCCT GCATCGCTTA CATCCGGCTC ACGCAGTACA TTGACGGGCA1561GGGCCGGCCC CGCACCAGCC AGTCTGAGGA GACCCGCGTG TGGCACCGCC GCGACGGCAA1621GTGGCAGAAC GTGCACTTCC ACTGCTCGGG CGCGCCTGTG GCCCCGCTGC AGTGAAGAGC1681TGCGCCCTGG TTTCGCCGGA CAGAGTTGGT GTTTGGAGCC CGACTGCCCT CGGGCACACG1741GCCTGCCTGT CGCATGTTTG TGTCTGCCTC GTTCCCTCCC CTGGTTCCTG TGTGTGCAGA1801AAAACAAGAC CAGATGTGAT TTGTTGENBANK ID: NM_001677.1DEFINITION HOMO SAPIENS ATPASE, NA+K+TRANSPORTING, BETA 1 POLYPEPTIDE(ATP1B1), MRNA.VERSION NM_001677.1 GI:4502276CDS 127..10381GAATTCATGC TAAATTGCTG GAAGGCTGCG TCTCTGCTGT GGTGTCAGTT CCGGATGCCT61CATCGCCAGG GGCGCGCCGC AGCCACCCAC CCTCCGGACC GCGGCAGCTG CTGACCCGCC121ATCGCCATGG CCCGCGGGAA AGCCAAGGAG GAGGGCAGCT GGAAGAAATT CATCTGGAAC181TCAGAGAAGA AGGAGTTTCT GGGCAGGACC GGTGGCAGTT GGTTTAAGAT CCTTCTATTC241TACGTAATAT TTTATGGCTG CCTGGCTGGC ATCTTCATCG GAACCATCCA AGTGATGCTG301CTCACCATCA GTGAATTTAA GCCCACATAT CAGGACCGAG TGGCCCCGCC AGGATTAACA361CAGATTCCTC AGATCCAGAA GACTGAAATT TCCTTTCGTC CTAATGATCC CAAGAGCTAT421GAGGCATATG TACTGAACAT AGTTAGGTTC CTGGAAAAGT ACAAAGATTC AGCCCAGAGG481GATGACATGA TTTTTGAAGA TTGTGGCGAT GTGCCCAGTG AACCGAAAGA ACGAGGAGAC541TTTAATCATG AACGAGGAGA GCGAAAGGTC TGCAGATTCA AGCTTGAATG GCTGGGAAAT601TGCTCTGGAT TAAATGATGA AACTTATGGC TACAAAGAGG GCAAACCGTG CATTATTATA661AAGCTCAACC GAGTTCTAGG CTTCAAACCT AAGCCTCCCA AGAATGAGTC CTTGGAGACT721TACCCAGTGA TGAAGTATAA CCCAAATGTC CTTCCCGTTC AGTGCACTGG CAAGCGAGAT781GAAGATAAGG ATAAAGTTGG AAATGTGGAG TATTTTGGAC TGGGCAACTC CCCTGGTTTT841CCTCTGCAGT ATTATCCGTA CTATGGCAAA CTCCTGCAGC CCAAATACCT GCAGCCCCTG901CTGGCCGTAC AGTTCACCAA TCTTACCATG GACACTGAAA TTCGCATAGA GTGTAAGGCG961TACCGTGAGA ACATTGGGTA CAGTGAGAAA GACCGTTTTC AGGGACGTTT TGATGTAAAA1021ATTGAAGTTA AGAGCTGATC ACAAGCACAA ATCTTTCCCA CTAGCCATTT AATAAGTTAA1081AAAAAGATAC AAAAACAAAA ACCTACTAGT CTTGAACAAA CTGTCATACG TATGGGACCT1141ACACTTAATC TATATGCTTT ACACTAGCTT TCTGCATTTA ATAGGTTAGA ATGTAAATTA1201AAGTGTAGCA ATAGCAACAA AATATTTATT CTACTGTAAA TGACAAAAGA AAAAGAAAAA1261TTGAGCCTTG GGACGTGCCC ATTTTTACTG TAAATTATGA TTCCGTAACT GACCTTGTAG1321TAAGCAGTGT TTCTGGCCCC TAAGTATTGC TGCCTTGTGT ATTTTATTTA GTGTACAGTA1381CTACAGGTGC ATACTCTGGT CATTTTTCAA GCCATGTTTT ATTGTATCTG TTTTCTACTT1441TATGTGAGCA AGGTTTGCTG TCCAAGGTGT AAATATTCAA CGGGAATAAA ACTGGCATGG1501TAATTTTTTT TTTTTGTTTG TTTTTTGTTT TTTGGCTCTT TCAAAGGTAA TGGCCCATCG1561ATGAGCATTT TTAACATACT CCATAGTCTT TTCCTGTGGT GTTAGGTCTT TATTTTTATT1621TTTTTCCTGG GGGCTGGGGT CGGGGTTTGT CATGGGGGAA CTGCCCTTTA AATTTTAAGT1681GACACTACAG AAAAACACAA AAAGGTGATG GGTTGTGTTA TGCTTGTATT GAATCCTGTC1741TTGACATCTC TTGCCTTGTC CTCCGGTATG TTCTAAAGCT GTGTCTGAGA TCTGGATCTG1801CCCATCACTT TGGCCTAGGG ACAGGGCTAA TTAATTTGCT TTATACATTT TCTTTTACTT1861TCCTTTTTTC CTTTCTGGAG GCATCACATG CTGGTGCTGT GTCTTTATGA ATGTTTTAAC1921CATTTTCATG GTGGAAGAAT TTTATATTTA TGCAGTTGTA CAATTTTATT TTTTTCTGCA1981AGAAAAAGTG TAATGTATGA AATAAACCAA AGTCACTTGT TTGAAAATAA ATCTTTATTT2041TGAACTTTAT AAAAGCAATG CAGTACCCCA TAGACTGGTG TTAAATGTTG TCTACACTGC2101AAAATCCATG TTCTAACATA TGTAATAATT GCCAGGAGTA CAGTGCTCTT GTTGATCTTG2161TATTCAGTCA GGTTAAAACA ACGGACAATA AAAGAATGAA CCGAATTCGENBANK ID: U82535.1VERSION U82535.1 GI:2149155CDS 36..1775/CODON_START=1MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQKQRAGLENMDRAAQRFRLQNPDLDSEALLALPLFQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPNARDVESLALCLRALLCEDMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAFLVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDINDKNLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSSGENBANK ID: NM_000789.1DEFINITION HOMO SAPIENS DIPEPTIDYL CARBOXYPEPTIDASE 1 (ANGIOTENSIN ICONVERTING ENZYME) (ACE), MRNA.VERSION NM_000789.1 GI:4503272CDS 23..39431GCCGAGCACC GCGCACCGCG TCATGGGGGC CGCCTCGGGC CGCCGGGGGC CGGGGCTGCT61GCTGCCGCTG CCGCTGCTGT TGCTGCTGCC GCCGCAGCCC GCCCTGGCGT TGGACCCCGG121GCTGCAGCCC GGCAACTTTT CTGCTGACGA GGCCGGGGCG CAGCTCTTCG CGCAGAGCTA181CAACTCCAGC GCCGAACAGG TGCTGTTCCA GAGCGTGGCC GCCAGCTGGG CGCACGACAC241CAACATCACC GCGGAGAATG CAAGGCGCCA GGAGGAAGCA GCCCTGCTCA GCCAGGAGTT301TGCGGAGGCC TGGGGCCAGA AGGCCAAGGA GCTGTATGAA CCGATCTGGC AGAACTTCAC361GGACCCGCAG CTGCGCAGGA TCATCGGAGC TGTGCGAACC CTGGGCTCTG CCAACCTGCC421CCTGGCTAAG CGGCAGCAGT ACAACGCCCT GCTAAGCAAC ATGAGCAGGA TCTACTCCAC481CGCCAAGGTC TGCCTCCCCA ACAAGACTGC CACCTGCTGG TCCCTGGACC CAGATCTCAC541CAACATCCTG GCTTCCTCGC GAAGCTACGC CATGCTCCTG TTTGCCTGGG AGGGCTGGCA601CAACGCTGCG GGCATCCCGC TGAAACCGCT GTACGAGGAT TTCACTGCCC TCAGCAATGA661AGCCTACAAG CAGGACGGCT TCACAGACAC GGGGGCCTAC TGGCGCTCCT GGTACAACTC721CCCCACCTTC GAGGACGATC TGGAACACCT CTACCAACAG CTAGAGCCCC TCTACCTGAA781CCTCCATGCC TTCGTCCGCC GCGCACTGCA TCGCCGATAC GGAGACAGAT ACATCAACCT841CAGGGGACGC ATCCCTGCTC ATCTGCTGGG AGACATGTGG GCCCAGAGCT GGGAAAACAT901CTACGACATG GTGGTGCCTT TCCCAGACAA GCCCAACCTC GATGTCACCA GTACTATGCT961GCAGCAGGGC TGGAACGCCA CGCACATGTT CCGGGTGGCA GAGGAGTTCT TCACCTCCCT1021GGAGCTCTCC CCCATGCCTC CCGAGTTCTG GGAAGGGTCG ATGCTGGAGA AGCCGGCCGA1081CGGGCGGGAA GTGGTGTGCC ACGCCTCGGC TTGGGACTTC TACAACAGGA AAGACTTCAG1141GATCAAGCAG TGCACACGGG TCACGATGGA CCAGCTCTCC ACAGTGCACC ATGAGATGGG1201CCATATACAG TACTACCTGC AGTACAAGGA TCTGCCCGTC TCCCTGCGTC GGGGGGCCAA1261CCCCGGCTTC CATGAGGCCA TTGGGGACGT GCTGGCGCTC TCGGTCTCCA CTCCTGAACA1321TCTGCACAAA ATCGGCCTGC TGGACCGTGT CACCAATGAC ACGGAAAGTG ACATCAATTA1381CTTGCTAAAA ATGGCACTGG AAAAAATTGC CTTCCTGCCC TTTGGCTACT TGGTGGACCA1441GTGGCGCTGG GGGGTCTTTA GTGGGCGTAC CCCCCCTTCC CGCTACAACT TCGACTGGTG1501GTATCTTCGA ACCAAGTATC AGGGGATCTG TCCTCCTGTT ACCCGAAACG AAACCCACTT1561TGATGCTGGA GCTAAGTTTC ATGTTCCAAA TGTGACACCA TACATCAGGT ACTTTGTGAG1621TTTTGTCCTG CAGTTCCAGT TCCATGAAGC CCTGTGCAAG GAGGCAGGCT ATGAGGGCCC1681ACTGCACCAG TGTGACATCT ACCGGTCCAC CAAGGCAGGG GCCAAGCTCC GGAAGGTGCT1741GCAGGCTGGC TCCTCCAGGC CCTGGCAGGA GGTGCTGAAG GACATGGTCG GCTTAGATGC1801CCTGGATGCC CAGCCGCTGC TCAAGTACTT CCAGCCAGTC ACCCAGTGGC TGCAGGAGCA1861GAACCAGCAG AACGGCGAGG TCCTGGGCTC GCCCGAGTAC CAGTGGCACC CGCCGTTGCC1921TGACAACTAC CCGGAGGGCA TAGACCTGGT GACTGATGAG GCTCAGGCCA CCAAGTTTGT1981GGAGGAATAT GACCGGACAT CCCAGGTGGT GTGGAACGAG TATGCCGAGG CCAACTGGAA2041CTACAACACC AACATCACCA CAGACACCAG CAAGATTCTG CTGCAGAAGA ACATGCAAAT2101AGCCAACCAC ACCCTGAAGT ACGGCACCCA GGCCAGGAAG TTTGATGTGA ACCAGTTGCA2161GAACACCACT ATCAAGCGGA TCATAAAGAA GGTTCAGGAC CTAGAACGGG CAGCGCTGCC2221TGCCCAGGAG CTGGAGGAGT ACAACAAGAT CCTGTTGGAT ATGGAAACCA CCTACAGCGT2281GGCCACTGTG TGCCACCCGA ATGGCAGCTG CCTGCAGCTC GAGCCAGATC TGACGAATGT2341GATGGCCACA TCCCGGAAAT ATGAAGACCT GTTATGGGCA TGGGAGGGCT GGCGAGACAA2401GGCGGGGAGA GCCATCCTCC AGTTTTACCC GAAATACGTG GAACTCATCA ACCAGGCTGC2461CCGGCTCAAT GGCTATGTAG ATGCAGGGGA CTCGTGGAGG TCTATGTACG AGACACCATC2521CCTGGAGCAA GACCTGGAGC GGCTCTTCCA GGAGCTGCAG CCACTCTACC TCAACCTGCA2581TGCCTACGTG CGCCGGGCCC TGCACCGTCA CTACGGGGCC CAGCACATCA ACCTGGAGGG2641GCCCATTCCT GCTCACCTGC TGGGGAACAT GTGGGCGCAG ACCTGGTCCA ACATCTATGA2701CTTGGTGGTG CCCTTCCCTT CAGCCCCCTC GATGGACACC ACAGAGGCTA TGCTAAAGCA2761GGGCTGGACG CCCAGGAGGA TGTTTAAGGA GGCTGATGAT TTCTTCACCT CCCTGGGGCT2821GCTGCCCGTG CCTCCTGAGT TCTGGAACAA GTCGATGCTG GAGAAGCCAA CCGACGGGCG2881GGAGGTGGTC TGCCACGCCT CGGCCTGGGA CTTCTACAAC GGCAAGGACT TCCGGATCAA2941GCAGTGCACC ACCGTGAACT TGGAGGACCT GGTGGTGGCC CACCACGAAA TGGGCCACAT3001CCAGTATTTC ATGCAGTACA AAGACTTACC TGTGGCCTTG AGGGAGGGTG CCAACCCCGG3061CTTCCATGAG GCCATTGGGG ACGTGCTAGC CCTCTCAGTG TCTACGCCCA AGCACCTGCA3121CAGTCTCAAC CTGCTGAGCA GTGAGGGTGG CAGCGACGAG CATGACATCA ACTTTCTGAT3181GAAGATGGCC CTTGACAAGA TCGCCTTTAT CCCCTTCAGC TACCTCGTCG ATCAGTGGCG3241CTGGAGGGTA TTTGATGGAA GCATCACCAA GGAGAACTAT AACCAGGAGT GGTGGAGCCT3301CAGGCTGAAG TACCAGGGCC TCTGCCCCCC AGTGCCCAGG ACTCAAGGTG ACTTTGACCC3361AGGGGCCAAG TTCCACATTC CTTCTAGCGT GCCTTACATC AGGTACTTTG TCAGCTTCAT3421CATCCAGTTC CAGTTCCACG AGGCACTGTG CCAGGCAGCT GGCCACACGG GCCCCCTGCA3481CAAGTGTGAC ATGTACCACT CCAAGGAGGC CGGGCAGCGC CTGGCGACCG CCATGAAGCT3541GGGCTTCAGT AGGCCGTGGC CGGAAGCCAT GCAGCTGATC ACGGGCCAGC CCAACATGAG3601CGCCTCGGCC ATGTTGAGCT ACTTCAAGCC GCTGCTGGAC TGGCTCCGCA CGGAGAACGA3661GCTGCATGGG GAGAAGCTGG GCTGGCCGCA GTACAACTGG ACGCCGAACT CCGCTCGCTC3721AGAAGGGCCC CTCCCAGACA GCGGCCGCGT CAGCTTCCTG GGCCTGGACC TGGATGCGCA3781GCAGGCCCGC GTGGGCCAGT GGCTGCTGCT CTTCCTGGGC ATCGCCCTGC TGGTAGCCAC3841CCTGGGCCTC AGCCAGCGGC TCTTCAGCAT CCGCCACCGC AGCCTCCACC GGCACTCCCA3901CGGGCCCCAG TTCGGCTCCG AGGTGGAGCT GAGACACTCC TGAGGTGACC CGGCTGGGTC3961GGCCCTGCCC AAGGGCCTCC CACCAGAGAC TGGGATGGGA ACACTGGTGG GCAGCTGAGGGENBANK ID: XM_052144.2DEFINITION HOMO SAPIENS APOLIPOPROTEIN A-IV (APOA4), MRNA.VERSION XM_052144.2 GI:15314431CDS 114..1304/CODON_START=11AGTTCCCACT GCAGCGCAGG TGAGCTCTCC TGAGGACCTC TCTGTCAGCT CCCCTGATTG61TAGGGAGGAT CCAGTGTGGC AAGAAACTCC TCCAGCCCAG CAAGCAGCTC AGGATGTTCC121TGAAGGCCGT GGTCCTGACC CTGGCCCTGG TGGCTGTCGC CGGAGCCAGG GCTGAGGTCA181GTGCTGACCA GGTGGCCACA GTGATGTGGG ACTACTTCAG CCAGCTGAGC AACAATGCCA241AGGAGGCCGT GGAACATCTC CAGAAATCTG AACTCACCCA GCAACTCAAT GCCCTCTTCC301AGGACAAACT TGGAGAAGTG AACACTTACG CAGGTGACCT GCAGAAGAAG CTGGTGCCCT361TTGCCACCGA GCTGCATGAA CGCCTGGCCA AGGACTCGGA GAAACTGAAG GAGGAGATTG421GGAAGGAGCT GGAGGAGCTG AGGGCCCGGC TGCTCCGCCA TGCCAATGAG GTGAGCCAGA481AGATGGGGGA CAACCTGCGA GAGCTTCAGC AGCGCCTGGA GCCCTACGCG GACCAGCTGC541GCACCCAGGT CAACACGCAG GCCGAGCAGC TGCGGCGCCA GCTGACCCCC TACGCACAGC601GCATGGAGAG AGTGCTGCGG GAGAACGCCG ACAGCCTGCA GGCCTCGCTG AGGCCCCACG661CCGACGAGCT CAAGGCCAAG ATCGACCAGA ACGTGGAGGA GCTCAAGGGA CGCCTTACGC721CCTACGCTGA CGAATTCAAA GTCAAGATTG ACCAGACCGT GGAGGAGCTG CGCCGCAGCC781TGGCTCCCTA TGCTCAGGAC ACGCAGGAGA AGCTCAACCA CCAGCTTGAG GGCCTGACCT841TCCAGATGAA GAAGAACGCC GAGGAGCTCA AGGCCAGGAT CTCGGCCAGT GCCGAGGAGC901TGCGGCAGAG GCTGGCGCCC TTGGCCGAGG ACGTGCGTGG CAACCTGAGG GGCAACACCG961AGGGGCTGCA GAAGTCACTG GCAGAGCTGG GTGGGCACCT GGACCAGCAG GTGGAGGAGT1021TCCGACGCCG GGTGGAGCCC TACGGGGAAA ACTTCAACAA AGCCCTGGTG CAGCAGATGG1081AACAGCTCAG GCAGAAACTG GGCCCCCATG CGGGGGACGT GGAAGGCCAC TTGAGCTTCC1141TGGAGAAGGA CCTGAGGGAC AAGGTCAACT CCTTCTTCAG CACCTTCAAG GAGAAAGAGA1201GCCAGGACAA GACTCTCTCC CTCCCTGAGC TGGAGCAACA GCAGGAACAG CAGCAGGAGC1261AGCAGCAGGA GCAGGTGCAG ATGCTGGCCC CTTTGGAGAG CTGAGCTGCC CCTGGTGCAC1321TGGCCCCACC CTCGTGGACA CCTGCCCTGC CCTGCCACCT GTCTGTCTGT CTGTCCCAAA1381GAAGTTCTGG TATGAACTTG AGGACACATG TCCAGTGGGA GGTGAGACCA CCTCTCAATA1441TTCAATAAAG CTGCTGAGAA TCTAGCCTCGENBANK ID: M29366.1DEFINITION HUMAN EFIDERMAL GROWTH FACTOR RECEPTOR (ERBB3) MRNA, COMPLETECDS.VERSION M29366.1 GI:181979CDS 100..4128/CODON_START=11ACCAATTCGC CAGCGGTTCA GGTGGCTCTT GCCTCGATGT CCTAGCCTAG GGGCCCCCGG61GCCGGACTTG GCTGGGCTCC CTTCACCCTC TGCGGAGTCA TGAGGGCGAA CGACGCTCTG121CAGGTGCTGG GCTTGCTTTT CAGCCTGGCC CGGGGCTCCG AGGTGGGCAA CTCTCAGGCA181GTGTGTCCTG GGACTCTGAA TGGCCTGAGT GTGACCGGCG ATGCTGAGAA CCAATACCAG241ACACTGTACA AGCTCTACGA GAGGTGTGAG GTGGTGATGG GGAACCTTGA GATTGTGCTC301ACGGGACACA ATGCCGACCT CTCCTTCCTG CAGTGGATTC GAGAAGTGAC AGGCTATGTC361CTCGTGGCCA TGAATGAATT CTCTACTCTA CCATTGCCCA ACCTCCGCGT GGTGCGAGGG421ACCCAGGTCT ACGATGGGAA GTTTGCCATC TTCGTCATGT TGAACTATAA CACCAACTCC481AGCCACGCTC TGCGCCAGCT CCGCTTGACT CAGCTCACCG AGATTCTGTC AGGGGGTGTT541TATATTGAGA AGAACGATAA GCTTTGTCAC ATGGACACAA TTGACTGGAG GGACATCGTG601AGGGACCGAG ATGCTGAGAT AGTGGTGAAG GACAATGGCA GAAGCTGTCC CCCCTGTCAT661GAGGTTTGCA AGGGGCGATG CTGGGGTCCT GGATCAGAAG ACTGCCAGAC ATTGACCAAG721ACCATCTGTG CTCCTCAGTG TAATGGTCAC TGCTTTGGGC CCAACCCCAA CCAGTGCTGC781CATGATGAGT GTGCCGGGGG CTGCTCAGGC CCTCAGGACA CAGACTGCTT TGCCTGCCGG841CACTTCAATG ACAGTGGAGC CTGTGTACCT CGCTGTCCAC AGCCTCTTGT CTACAACAAG901CTAACTTTCC AGCTGGAACC CAATCCCCAC ACCAAGTATC AGTATGGAGG AGTTTGTGTA961GCCAGCTGTC CCCATAACTT TGTGGTGGAT CAAACATCCT GTGTCAGGGC CTGTCCTCCT1021GACAAGATGG AAGTAGATAA AAATGGGCTC AAGATGTGTG AGCCTTGTGG GGGACTATGT1081CCCAAAGCCT GTGAGGGAAC AGGCTCTGGG AGCCGCTTCC AGACTGTGGA CTCGAGCAAC1141ATTGATGGAT TTGTGAACTG CACCAAGATC CTGGGCAACC TGGACTTTCT GATCACCGGC1201CTCAATGGAG ACCCCTGGCA CAAGATCCCT GCCCTGGACC CAGAGAAGCT CAATGTCTTC1261CGGACAGTAC GGGAGATCAC AGGTTACCTG AACATCCAGT CCTGGCCGCC CCACATGCAC1321AACTTCAGTG TTTTTTCCAA TTTGACAACC ATTGGAGGCA GAAGCCTCTA CAACCGGGGC1381TTCTCATTGT TGATCATGAA GAACTTGAAT GTCACATCTC TGGGCTTCCG ATCCCTGAAG1441GAAATTAGTG CTGGGCGTAT CTATATAAGT GCCAATAGGC AGCTCTGCTA CCACCACTCT1501TTGAACTGGA CCAAGGTGCT TCGGGGGCCT ACGGAAGAGC GACTAGACAT CAAGCATAAT1561CGGCCGCGCA GAGACTGCGT GGCAGAGGGC AAAGTGTGTG ACCCACTGTG CTCCTCTGGG1621GGATGCTGGG GCCCAGGCCC TGGTCAGTGC TTGTCCTGTC GAAATTATAG CCGAGGAGGT1681GTCTGTGTGA CCCACTGCAA CTTTCTGAAT GGGGAGCCTC GAGAATTTGC CCATGAGGCC1741GAATGCTTCT CCTGCCACCC GGAATGCCAA CCCATGGAGG GCACTGCCAC ATGCAATGGC1801TCGGGCTCTG ATACTTGTGC TCAATGTGCC CATTTTCGAG ATGGGCCCCA CTGTGTGAGC1861AGCTGCCCCC ATGGAGTCCT AGGTGCCAAG GGCCCAATCT ACAAGTACCC AGATGTTCAG1921AATGAATGTC GGCCCTGCCA TGAGAACTGC ACCCAGGGGT GTAAAGGACC AGAGCTTCAA1981GACTGTTTAG GACAAACACT GGTGCTGATC GGCAAAACCC ATCTCACAAT GGCTTTGACA2041GTGATAGCAG GATTGGTAGT GATTTTCATG ATGCTGGGCG GCACTTTTCT CTACTGGCGT2101GGGCGCCGGA TTCAGAATAA AAGGGCTATG AGGCGATACT TGGAACGGGG TGAGAGCATA2161GAGCCTCTGG ACCCCAGTGA GAAGGCTAAC AAAGTCTTGG CCAGAATCTT CAAAGAGACA2221GAGCTAAGGA AGCTTAAAGT GCTTGGCTCG GGTGTCTTTG GAACTGTGCA CAAAGGAGTG2281TGGATCCCTG AGGGTGAATC AATCAAGATT CCAGTCTGCA TTAAAGTCAT TGAGGACAAG2341AGTGGACGGC AGAGTTTTCA AGCTGTGACA GATCATATGC TGGCCATTGG CAGCCTGGAC2401CATCCCCACA TTGTAAGGCT GCTGGGACTA TGCCCAGGGT CATCTCTGCA GCTTGTCACT2461CAATATTTGC CTCTGGGTTC TCTGCTGGAT CATGTGAGAC AACACCGGGG GGCACTGGGG2521CCACAGCTGC TGCTCAACTG GGGAGTACAA ATTGCCAAGG GAATGTACTA CCTTGAGGAA2581CATGGTATGG TGCATAGAAA CCTGGCTGCC CGAAACGTGC TACTCAAGTC ACCCAGTCAG2641GTTCAGGTGG CAGATTTTGG TGTGGCTGAC CTGCTGCCTC CTGATGATAA GCAGCTGCTA2701TACAGTGAGG CCAAGACTCC AATTAAGTGG ATGGCCCTTG AGAGTATCCA CTTTGGGAAA2761TACACACACC AGAGTGATGT CTGGAGCTAT GGTGTGACAG TTTGGGAGTT GATGACCTTC2821GGGGCAGAGC CCTATGCAGG GCTACGATTG GCTGAAGTAC CAGACCTGCT AGAGAAGGGG2881GAGCGGTTGG CACAGCCCCA GATCTGCACA ATTGATGTCT ACATGGTGAT GGTCAAGTGT2941TGGATGATTG ATGAGAACAT TCGCCCAACC TTTAAAGAAC TAGCCAATGA GTTCACCAGG3001ATGGCCCGAG ACCCACCACG GTATCTGGTC ATAAAGAGAG AGAGTGGGCC TGGAATAGCC3061CCTGGGCCAG AGCCCCATGG TCTGACAAAC AAGAAGCTAG AGGAAGTAGA GCTGGAGCCA3121GAACTAGACC TAGACCTAGA CTTGGAAGCA GAGGAGGACA ACCTGGCAAC CACCACACIG3181GGCTCCGCCC TCAGCCTACC AGTTGGAACA CTTAATCGGC CACGTGGGAG CCAGAGCCTT3241TTAAGTCCAT CATCTGGATA CATGCCCATG AACCAGGGTA ATCTTGGGCA GTCTTGCCAG3301GAGTCTGCAG TTTCTGGGAG CAGTGAACGG TGCCCCCGTC CAGTCTCTCT ACACCCAATC3361CCACGGGGAT GCCTGGCATC AGAGTCATCA GAGGGGCATG TAACAGGCTC TGAGGCTGAG3421CTCCAGCAGA AAGTGTCAAT GTGTAGAAGC CCGAGCAGCA GGCGGAGGCG ACGGCCACGC3481GGAGATAGGG CCTACCATTC CCAGCGCCAC AGTCTGCTGA CTCCTGTTAC CCCACTCTCC3541CCACCCGGGT TAGAGGAAGA GGATGTCAAC GGTTATGTCA TGCCAGATAC ACACCTCAAA3601GGTACTCCCT CCTCCCGGGA AGGCACCCTT TCTTCAGTGG GTCTTAGTTC TGTCCTGGGT3661ACTGAAGAAG AAGATGAAGA TGAGGAGTAT GAATACATGA ACCGGAGGAG AAGGCACAGT3721CCACCTCATC CCCCTAGGCC AAGTTCCCTT GAGGAGCTGG GTTATGAGTA CATGGATGTG3781GGGTCAGACC TCAGTGCCTC TCTGGGCAGC ACACAGAGTT GCCCACTCCA CGCTGTACGC3841ATCATGCCCA CTGCAGGCAC AACTCCAGAT GAAGACTATG AATATATGAA TCGGCAACGA3901GATGGAGGTG GTCCTGGGGG TGATTATGCA GCCATGGGGG CCTGCCCAGC ATCTGAGCAA3961GGGTATGAAG AGATGAGAGC TTTTCAGGGG CCTGGACATC AGGCCCCCCA TGTCCATTAT4021GCCCGCCTAA AAACTCTACG TAGCTTAGAG GCTACAGACT CTGCCTTTGA TAACCCTGAT4081TACTGGCATA GCAGGCTTTT CCCCAAGGCT AATGCCCAGA GAACGTAACT CCTGCTCCCT4141GTGGCACTCA GGGAGCATTT AATGGCAGCT AGTGCCTTTA GAGGGTACCG TCTTCTCCCT4201ATTCCCTCTC TCTCCCAGGT CCCAGCCCCT TTTCCCCAGT CCCAGACAAT TCCATTCAAT4261CTTTGGAGGC TTTTAAACAT TTTGACACAA AATTCTTATG GTATGTAGCC AGCTGTGCAC4321TTTCTTCTCT TTCCCAACCC CAGGAAAGGT TTTCCTTATT TTGTGTGCTT TGCCAGTCGC4381ATTCCTCAGC TTCTTCACAG GCACTCCTGG AGATATGAAG GATTACTCTC CATATCCCTT4441CCTCTCAGGC TCTTGACTAC TTGGAACTAG GCTCTTATGT GTGCCTTTGT TTCCCATCAG4501ACTGTCAAGA AGAGGAAAGG GAGGAAACCT AGCAGAGGAA AGTGTAATTT TGGTTTATGA4561CTCTTAACCC CCTAGAAAGA CAGAAGCTTA AAATCTGTGA AGAAAGAGGT TAGGAGTAGA4621TATTGATTAC TATCATAATT CAGCACTTAA CTATGAGCCA GGCATCATAC TAAACTTCAC4681CTACATTATC TCACTTAGTC CTTTATCATC CTTAAAACAA TTCTGTGACA TACATATTAT4741CTCATTTTAC ACAAAGGGAA GTCGGGCATG GTGGCTCATG CCTGTAATCT CAGCACTTTG4801GGAGGCTGAG GCAGAAGGAT TACCTGAGGC AAGGAGTTTG AGACCAGCTT AGCCAACATA4861GTAAGACCCC CATCTCTTTGENBANK ID: X54686VERSION X54686.1 GI:56909MCTKMEQAFYHDDSYAAAGYGRSPGSLSLHDYKLLKPTLALNLADPYRGLEGPGARGPGPEGSGAGSYFSGQGSDTGASLKLASTELERLIVPNSNGVITTTPTPPGQYPYPRGGGSGGGTGGGVTEEQEGFADGFVKALDDLQKMNHVTPPNVSLGASGGPQAGPGGVYAGPEPPPVYTNLSSYSPASAPSGGSGTAVGTGSSYPTATISYLPHAPPFAGGNPAQLGLSRGASAFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSAAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAFGENBANK ID: D26307VERSION D26307.1 GI:450471METPFYGEEALSGLAAGASSVAGAAGAPGGGGPAPPGRAFPGAPPTSSNLKKQALTLSLAEQGAAGLKPGSATAPSALRPDGAPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSTQFLYPKVAASEEQEFAEGFVKALEDLHKQSQLGAATAATSGAPAPPAPADLAATPGATETPVYANLSSFAGGAGPPGGAATVAFAAEPVPFPPPPGALGPPPPPHPPRLAALKDEPQTVPDVPSFGDSPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAYGENBANK ID: NM_012747.1VERSION NM_012747.1 GI:6981591MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAMASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTPTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPMGENBANKID: L26267.1VERSION L26267.1 GI:425471REILNPPEKETQGEGPSLFMASTKTEAIAPASTMEDKEEDVGFQDNLFLEKALQLAKRHANALFDYAVTGDVKNLLAVQRHLTAVQDEN0DSVLHLAIIHLEAQLVRDLLEVTSGSISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLHLAAKEGHDKILGVLLKNSKAALLINHPNGEGLNAIHIAVMSNSLSCLQLLVAAGAEVNAQEQKSGRTALHLAVEYDNISLAGCLLLEGDALVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTFLDMAANWQVFDILNGKFYEFVFTSDDILPQGDIKQLTEDTRLQLCKLLEIFDPDKNNATLAQKLGLGILNNAFRLSFAPSKTLMDNYEVSGGTIKELVEALRQMGYTEAIEVIQAAFRTPETTASSPVTTAQAHLLPLSSSSTRQHIDELRDNDSVCDSGVETSFRKLSFSESLTGDGPLLSLNKMFHNYGQDGPIEGKIGENEANK ID:M3435 6.1VERSION M34356.1 GI:181042MTMESGAENQQSGDAAVTEAENQQMTVQAQFQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQFSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAFGVFRIEEEKSEEETSAFAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAFGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDYCHKSDGENBANK ID:X68193.1VERSION X68193.1 GI:53353MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLEQEYIDLKDRPFFFGLVKYMNSGPVVAMVWEGLNVVKTGRVNLGETNPADSKFGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYEGENBANKID: U29200.1VERSION U29200.1 GI:924934MANLERTFIAIKPDGVQRGENBANK ID: L35572VERSION L35572.1 GI:531219MNVHCAGCERFILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDFLQDDPKETDNSTSSDKETANNENEEQNSGTKRRGFRTTIKAKQLETLKAAFAATFKFTRHIREQLAQETGLNMRVIQVWFDNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYGSDYVAPGGNYDFFAHGPPSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHGADNPRFTDMISHPDTPSPEPGLPGALHPNPGEVFSGGPSPPFPMSGTSGY5GPLSHPNPELNEAAVWGENBANK ID: X55787.1VERSION X55797.1 GI:296022MKAAVDLKPTLTIIKTEKVDLELFPSPENECADVPLSTPSSKEMMSQALKSYFSGFTKEQQRRGIPKDPRQWTDTHVRDWVMAVNEFSLKGVDFHKFCMSGAAVCALGKECFLELAPDFVGDILWEELEILQKEDVKPYQVNGANPTYPESCYTSVYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTETLQTDYFRIKQEVLTPNNMCLGRASRGKLGGQDSFESVESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDYEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDCNEFKLSDPDEVARRWGKRKNKPSMNYEKLSRALRYYYDKNIIHKTAGNAYVYAFVCDLQSLLGYTPEELHAMLDVKPDADGENBANK ID: M11507.1DEFINITION Human transferrln receptorVERSION M11507.1 GI:339515MMDQARSAFSNLFGGEFLSYTRFSLARQVDGDNSHVENKLAVDEEENADNNTKANVTKPKRCSGSICYCTIAVIVFFLIGFMIGYLGYCKGVEPKTECERLAGTESPVREEFGEDFFAARRLYWDDLKRKLSEKLQSTDFTSTIKLLNENSYVPREAGSQKDENLALYVENQFREFKLSKVWRDQHFVKTQVKDSAQNSVIIVDKNGRLVYLVENPGGYVAYSKAATVTCKLVHANFGTKKDFEDLYTPVNCSTVIVRAGKITFAEKVPNAESLNAIGVLIYMDQTKFFIVNAELSFFGHAHLGTGDPYTPGFPSFNHTQFPPSRSSGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEIKILNIFGVIKCFVEPDNYVVVGAQRDAWGP0AAKSGVGTALLLKLAQMFSDNVLKQGFQFSRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYTLIEKTMQNVKHPVTGQFLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCFCEDTDYPYLGTTMDTYKELIERIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNSQLLSFVRDLNQYRADIKEMGLSLQWLYSARGDFFPATSRLTTDFGNAEKTDRFVMKKLNDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSHTLPALLENLKLRKQNNCAFNETLFRNQLALATWTIQGAANALSGDVWDIDNEFGENBANK ID: AAA60255VERSION AAA60255.1 GI:1909271mteyklvvvg aggvgksalt iqllqnhfvd eydptledsy rkqvvidget clldildtag61qeeysamrdq ymrtgegflc vfainnsksf adlnlyreqi krvkdsddvp mvlvgnkcdl121ptrtvdtkqa helaksygip fietsaktrq gvedafytlv reirqyrmkk lnssddgtgg181cmglpcvvmGENBANK ID: AAB38309VERSION AAB38309.1 GI:14979311mslvlndlli ccrqlehdra terkkevekf krllrdpeti khldrhsdsk qgkylnwdav61frflqkyiqk eteclrlakp nvsastqasr qkknqeissl vkytikcanr raprlkcqel121lnyimdtvkd ssngalygad csnhllkdil svrkywceis qqqwlelfsv yfrlylkpsq181dvhrvlvari ihavtkgccs qtdglnskkfl dffskaiqca rqeksssgln hilaaltifi241ktlavnfrir vcelgdeilp tllyiwtqhr lndslkevii elfqlqiyih hpkgaktqek301gayestkwrs ilynlydllv neishlgsrg kyssgfrnia vkenllelma dichqvfned361trslelsqsy tttqressdy svpckrkkie lgwevikdhl qksqndfdlv pwlqiatqli421skypaslpnc elspllmils qllpqqrhge rtpyvlrclt evalcqdkrs nlessqksdl481lklwnkiwci tfrgisseqi qaenfgllga iiqgslvevd refwklftgs acrpscpavc541cltlalttsi vpgtvkmgie qnmcevnrsf slkesimkwl ltyqlegdle nstevppilh601snfphlvlek ilvslomknc kaamnffqsv pecehhqkdk eelsfsevee lflqttfdkm661dfltivrecg iekhqssigf svhqnlkesl drcllglseq llnnysseit nsetlvrcsr721llvgvlgcyc ymgviaeeea ykselfqkak slmqcaqesi tlfknktnee trigslrnmm781qlctrclsnc tkkspnkias gfflrlltsk lmndiadick slasflkkpf firgevesmed841dtngnlmeve dgssmnlfnd ypdssvsdan epgesqstig ainplaeeyl skgdllfldm901lkflclcvtt aqtntvsfra adirrkllml idsstleptk sihihmylmi lkelpgeeyp961lpmedvlell kplsnvcsly rrdqdvckti lnhvlhvvkn lgqsnmdsen trdaqgqflt1021vigafwhltk erkyifsvrm alvnclktll eadpyskwai lnvmgkdfpv nevftqflad1081nhhqvrmlaa esinrlfqdt kgdssrllka lplklqqtaf enaylkaqeg mremshsaen1141petldeiynr ksvlltliav vlscapicek qalfalcksv kenglephlv kkvlekvset1201fgyrrledfm ashldylvle wlnlqdteyn lsstpfilln ytniedtyrs cykvliphlv1261irshfdevks ianqigedwk slltdcfpki lvnilpytay egtrdsgmaq qretatkvyd1321mlksenllgk qidhitisni peivvellmt lhepanssas qstdlcdfsg dldpapnpph1381fpshvlkatf ayisnchktk ikaileilak spdsyqkill aiceqaaetn nvykkhrilk1441iyhlfvslll kdiksglgga watvlrdviy tlihylnqrp scimdvslrs fslccdllsq1501vcqtavtyck dalenhlhvl vgtliplvye qvevqkqvld llkylvidnk dnenlyitik1561lldpfpdhvv fkdlrltqqk ikysrgpfsl leeinhflsv svydalplcr leglkdlrrq1621lelhkdqmvd inrasqdnpq dglmvklvvn llqlskmain htgekevlea vgsclgevgp1681idfstiaiqh skdasytkal kltedkelqw tfimltylnn tlvedcvkvr saavtclkni1741latktghsfw eiykmttdpm laylqpfrts rkkflevprf dkenpfegld dinlwiplse1801nhdiwiktlt cafldsggtk ceilqllkpm cevktdfcqt vlpylihdil lqdtneswrn1861llsthvqgff tsclrhfsqt srsttpanld sesehffrcc ldkksgrtml avvdymrrqk1921rpssgtifnd atwldinyle vakvaqscaa hftallyaei yadkksmddq ekrslateeg1981sqsttissls ekskeetgis lqdllleiyr sigepdslyg cgggkmlqpi trlrtyehea2041mwgkalvtyd letaipsstr qagiiqalqn igichilavy lkgldyenkd wcpeleelhy2101qaawrnmqwd hctsvskeve gtsyheslyn alqslrdref stfyeslkya rvkeveemck2161rslesvysly ptlsrlqaig elesigelfs rsvthrqlse vyikwqkhsq llkdsdfsfq2221epimalrtvi leilmekemd nsqrecikdl ltkhlvelsi lartfkntql peralfqikq2281ynsvscgvse wqleeaqvfw akkeqslals ilkqmikkld ascaannpsl kltyteclrv2341cgnwlaetcl enpavimqty lekavevagn ydgessdelr ngkmkaflsl arfsdtqyqr2401ienymkssef enkqallkra keevgllreh klqtnrytvk vqreleldel alralkedrk2461rflckaveny incllsgeeh dmwvtrlcsl wlensgvsev ngmmkrdgmk iptykflplm2521yqlaarmgtk mmgglgfhev lnnlisrism dhphhtlfii lalananrde fltkpevarr2581sritknvpkq ssqldedrte aanrilctir srrpqmvrsv ealcdayill anldatqwkt2641qrkginipad qpitklknle dvvvptmeik vdhtgeygnl vtiqsfkaet rlaggvnlpk2701iidcvgsdgk errqlvkgrd dlrqdavmgq vfqmcntllq rntetrkrkl tictykvvpl2761sqrsgvlewc tgtvpigefl vnnedgahkr yrpndfsafq cqkkmmevqk ksfeekyevf2821mdvcqntqpv fryfcmekfl dpaiwfekrl aytrsvatss ivgyilglgd rhvqniline2881qsaelvhidl gvafeqgkil ptpetvpfrl trdivdgmgl tgvegvfrrc cektmevmrn2941sqetlitlve vllydplfdw tmnplkalyl qqrpedetel hptlnaddqe ckrnlsdidq3001sfdkvaervl mrlqeklkgv eegtvlsvgg qvnlliqqai dpknlsrlfp gwkawvGENBANK ID: AAA59145.1VERSION AAA59145.1 GI:3070581mlkpslpfts llflqlpllg vglnttiltp ngnedttadf flttmptdsl svstlplpev61qcfvfnveym nctwnsssep qptnltlhyw yknsdndkvq kcshyltsee itsgcqlqkk121eihlyqtfvv qlqdpreprr qatqmlklqn lvipwapenl tlhklsesql elnwnnrfln181hclehlvqyr tdwdhswteq svdyrhkfsl psvdgqkryt frvrsrfnpl cgsaqhwsew241shpihwgsnt skenptlfal eavvisvgsm gliisllovy fwlertmpri ptlknledlv301teyhgnfsaw sgvskglaes lqpdyserlc lvseippkgg algegpgasp cnqhspywap361pcytlkpetGENBANK ID: AAC50825.1VERSION AAC50825.1 GI:11179841mvaprplrrv vlfyggklcs magnfwqssh ylqwildkqd llkerqkdlk flseeeywkl61qifftnviqa lgehlklrqq viatatvyfk rfyaryslks idpvlmaptc vflaskveef121gvvsntrlia aatsvlktrf syafpkefpy rmnhilecef yllelmdccl ivyhpyrpll181qyvqdmgged mllplawriv ndtyrtdlcl lyppfmiala clhvacvvqq kdarqwfael241svdmekilei irvilklyeq wkntderkem atilskmpkp kpppnsegeq gpngsqnssy301sqsGENBANK ID: AAC50473.1VERSION AAC50473.1 GI:13143461mamssggsgg gvpeqedsvl frrgtgqsdd sdiwddtali kaydkavasf khalkngdic61etsgkpkttp krkpakknks qkkntaaslq qwkvgdkcsa iwsedgciyp atlasidfkr121etcvvvytgy gnreeqnlsd llspicevan nleqnaqene nesqvstdes ensrspgnks181dnikpksapw nsflpppppm pgprlgpgkp glkfngpppp pppppphlls cwlppfpsgp241piipppppic pdslddadal gsmliswyms gyhtgyymgf rqnqkegrcs hslnGENBANK ID: CAC15525VERSION CAC15525.1 GI:111375171mvsrdqahlg pkyvglwdtk srtdeelsfr agdvfhvark eeqwwwatll deaggavaqg61yvphnylaer etvesepwff qcisrseavr rlqaegnatg aflirvsekp sadyvlsvrd121tqavrhykiw rraggrlhln eavsflslpe lvnyhraqsl shglrlaapc rkhepeplph181wddwerpree ftlcrklgsg yfgevfeglw kdrvqvaikv isrdnllhqq mlqseiqamk241klrhkhilal yavvsvgdpv yiltelmakg sllellrdsd ekvlpvsell diawqvaegm301cylesqnyih rdlaarnilv gentlckvgd fglarliked vylshdhnip ykwtapeals361rghystksdv wsfglllhem fsrgqvpypg msnheaflrv dagyrmpcpl ecppsvhklm421ltcwcrdpeq rpcfkalrer lssftsyenp tGENBANK ID: AAB84296VERSION AAB84296.1 GI:26131351tsttvrglna strylfrvra svqqigdwsn tveettlglq saspvqesrv aedgldqqlv61iavvgsvsat cltiiaalla lvclrrsclh rrhtftyqsg sgeetilqfs sgtltltrrp121kpqpeplsyp vleGENBANK ID: X63594.1VERSION X63594.1 GI:57673MFQPAGHGQDWANEGPRDGLKKERLVDDRHDSGLDSNKDEDYEQMVKELREIRLQFQEAPLAAEPWKQQLTEDGDSFLHLAIIHEEKTLTMEVIGQVKGDLAFLNFQNNLQQTPLHLAVITNQPGIAEALLKAGCDPELRDFRGNTPLHLACEQGCLASVAVLTQTCTPQHLHSVLQATNYNGHTCLHLASIHGYLGIVEHLVTLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQTLPESEDEESYDTESEFTEDELPYDDCVFGGQRLTLGENBANK ID: AAB60641VERSION AAB60641.1 GI:5165151meqqdqsmke gmgttwllst pqhwlmqqfy netyygrtge fmedfpltll wsvtvsmfpf61ggfigsllvg plvnkfgrkg allfnnifsi vpailmgcsr vatsfeiiii srllvgicag121vssnvvpmyl gelapknlrg algvvpqlfi tvgilvaqif glrnllanvd gwpillgltg181vgaalqllll pffpespryl liqkkdeaaa kkalqtlrgw dsvdrevaei rqedeaekaa241gfisvlklfr mrslrwqlls iivlmggqql sgvnaiyyya dqiylsagvp eehvqyvtag301tgavnvvmtf cavfvvellg rrlllllgfs icliaccvlt aalalgdtvs wmpyisivcv361isyvlghaig pspipallit eiflqssrps afmvggsvhw lsnftvglif pfiqeglgpy421sfivfavic1 lttiyifliv petkaktfie ingiftkmnk vsevypekee lkelppvtse481qGENEANK ID: M29069VERSION M29069.1 GI:205553MLSCTTSTMPGMICKNSDLEFDSLKFCFYPEDDDIYFGGRNSTPPGEDIWKKEELLPTFRLSPGRALAEDSLEPANMATEMLLFEADLWSNPAEEEDIFGLKGLSGSSSNPVVLQDCMWSGFSSREKPETVVSEKLPGGCGSLAVGAGTLVPGAAAATSAGHARSGTAGVGRRKAAWLTELSHLDSECVDSAVIFFANKRESMPVATIPASAGPAISLGDHQGLSSSLEDFLSNSGYVEEGGEEIYVVMLGETQFSKTVTKLPTAAHSENAALTPECAQSGELILKRSDLIQEDHNYAAFPLPYAEDARPLKKPRSQDPLGPLKCVLRPKAPRLRSRSNSDLEDIERRRNHNRMERQRRDIMRSSFLNLRDLVPELVHNEKAAKVVILKKATEYIHTLQTDESKLLVEREKLYERKQQLLEKIKQSAVCGENBANK ID: M29039.1VERSION M29039.1 GI:186626MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADFYRSLKAPGARGPGPEGGQGGSYFSGQGSDTGASLKLASSELERLIVFNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNMVTPFNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVFEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVNTMVSNGCQLLLGVKGHAFGENBANK ID: X56681.1VERSION X56681.1 GI:34018METPFYGDEALSGLGGGASGSGGTFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAPAPASYPPAADGAPSAAPPDGLLASPDLGLIKLASPELERLIIQSNGLVTTTFTSSQFLYFKVAASEEQEFAEGFVKALEDLHKQNQLGAGRAAAAAAAAAGGPSGTATGSAPPGGELAPAAAAPEAPVYANLSSYAGAGGAGGAATVAFAAEPVPFPPPPPPGALGFFRLAALKDEPQTVFDVFSFGESFFLSFIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSMVNSGCQLLPQHQVPAYGENBANK ID: NM_003150.1VERSION NM_003150.1 GI:4507252MAQWNQLQQLDTRYLEQLHQLYSDSFFMELRDFLAFWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYGHNLRRIKQFLQSRYLEKFMEIARIVARCLWEESRLLQTAATAAQQGGQANMFTAAVVTEKQQMLEQHLQDVRKRVQQLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTGEELADWKRRQQIACIGGFFNICLDRLENWITSLAESQLQTRQQIKKLEELHQKVSYKGDFIVQHRFMLEERIVVELFRNLMKSAFWERQFCMFMHPDRPLVIKTGVQFTTKVRLLVKFFELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETMSLSVVVISNICQMFNAWASILWYNMLTNNFKNVNFFTKPPIGTWDGVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGFGVNYSGCQITWANFCKENNAGKGESYMVMLDNIIDLVKKYILALWNEGYIMGFISKEREFAILSTKFFGTELLRESESSKEGGVTETMVEKDISGKTQIQSVEFYTKQQLNNMSFAEIIMGYKIMDATNILLSFLVYLYFDIPKEEAFGKYCRFESGEHFEADFGSAAFYLKTKFICVTPTTCSNTIDLPMSPRALDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM

[0213]

	Number	Date	Country
	60281387	Apr 2001	US
	60302591	Jul 2001	US

Genetic analysis of peyer's patches and M cells and methods and compositions targeting peyer's patches and M cell receptors

Information

Publication Number

Date Filed

Date Published

Inventors

CPC

US Classifications

International Classifications

Abstract

Description

Claims

Provisional Applications (2)