Holcenberg et al., Biochemistry 17(3):411-417, 1978.* |
Minton, et al., “Nucleotide sequence of the Erwinia chrysanthemi NCPPB 1066 L-asparaginase gene”, Gene, 46:25-35 (1986). |
Kim, et al., “Asparaginase II of Saccharomyces cerevisiae”, J. Biol. Chem., 263:11948-11953, (1988). |
Ovejera, et al., “Efficacy of 6-Diazo-5-oxo-L-norleucine and N-[N-γ-Glutamyl-6-diazo-5-oxo-norleucinyl]-6-diazo-5-oxo-norleucine against Experimental Tumors in Conventional and Nude Mice”, Cancer Research, 39:3220-3224 (1979). |
Houchens, et al., “Therapy for Mouse Tumors and Human Tumor Xenografts With the Antitumor Antibiotic AT-125”, Cancer Treatment Reports, 63:473-476 (1979). |
Duvall, L.R., “6-Diazo-5-oxo-L-norleucine”, Cancer Chemother. Reports, 7:86-98 (1960). |
Roberts, J., “Purification and Properties of a Highly Potent Antitumor Glutaminase-Asparaginase from Pseudomonas 7A”, J. Biol. Chem., 251:2119-2123 (1976). |
Holcenberg, et al., “Physical Properties of Antitumor Glutaminase-Asparaginase from Pseudomonas 7A”, J. Biol. Chem., 251:5375-5380 (1976). |
Roberts, et al., “Biologic and Antineoplastic Effects of Enzyme-Mediated In Vivo Depletion of L-Glutamine, L-Tryptophan, and L-Histidine”, Cancer Treatment Reports, 63:1045-1054 (1979). |
Roberts, et al., “Inhibition of mouse retroviral disease by bioactive glutaminase-asparaginase”, J. Gen. Virol., 72:299-305 (1991). |
Bonthron, D.T., “L-Asparaginase II of Escherichia coli K-12: cloning, mapping and sequencing of the ansB gene”, Gene, 91:101-105 (1990). |
Nicolau, et al., “Liposomes as Carriers for in Vivo Gene Transfer and Expression”, Meth. Enzymol., 149:157-176 (1987). |
Wu, et al., “Receptor-mediated Gene Delivery in Vivo”, J. Biol. Chem., 266:14338-14342 (1991). |
Schmer, et al., “Kinetics of Uptake and Activity in Mouse Liver of Glutaminase Coupled to Desialated Orosomucoid”, Biochimica et Biophysica Acta, 538:397-405 (1978). |
Ollenschläeger, et al., “Intestinal Glutamine Metabolism of Patients with HIV-Infection”, Clinical Nutrition, 9:48-49 (1990). |
Roberts, et al., “Glutaminase has potent antiretroviral activity in vivo”, Abstract, Proc. Am. Assoc. Cancer Res., 30:454 (1989). |
Shapiro, et al., “Isolation, Characterization, and in Vitro Expression of a cDNA That Encodes the Kidney Isoenzyme of the Mitochondrial Glutaminase”, J. Biol. Chem., 266:18792-18796 (1991). |
Katunuma, et al., “Organ Specific Control of Glutamine Metabolism”, Adv. Enz. Reg., 5:55-69 (1967). |
Goldstein, L., “Relation of glutamate to ammonia production in the rat kidney”, Am. J. Physiol., 210:661-666 (1966). |
Curthoys, et al., “The Distribution of Glutaminase Isoenzymes in the Various Structures of the Nephron in Normal, Acidotic, and Alkalotic Rat Kidney”, J. Biol. Chem., 248:162-168 (1973). |
Goldstein, Leon, “Relation of glutamate to ammonia production in the rat kidney”, pp. 661-666. |
Smith, Eleanor, Molecular Cloning of a cDNA for Rat Hepatic Glutaminase, Dec. 18, 1980, pp. 10631-10636. |
Smith, Eleanor M., “Rat Hepatic Glutaminase: Purification and Immunochemical Characterization”, 1987 pp. 740-751. |
Banner, Carl, “Isolation of a cDNA for rat brain glutaminase” 1988 pp. 247-254. |