Human nucleic acid sequences from prostate tumor tissue

Abstract

Human nucleic acid sequences—mRNA, cDNA, genomic sequences—from tissue of prostate tumors, which code for gene products or parts thereof and their use, are described. In addition, the polypeptides that can be obtained by way of the sequences and their use are described.

Description

[0001] The invention relates to human nucleic acid sequences—mRNA, cDNA, genomic sequences—from tissue of prostate tumors that code for gene products or parts thereof and their use.

[0002] The invention furthermore relates to polypeptides that can be obtained via the sequences and their use.

[0003] One very common type of cancer is prostate cancer, for control of which new therapies are necessary. Previously used therapies based on the blocking of hormone effects are very often ineffective after a few years since the tumor becomes independent of the hormone, i.e., it continues to grow and forms metastases without the action of hormones.

[0004] The cancer phenomenon often goes along with overexpression or underexpression of certain genes in degenerated cells, it still being unclear whether these altered expression rates are the cause or the result of the malignant transformation. Identification of these genes would be an important step for development of new therapies against cancer. Spontaneous formation of cancer is often preceded by a host of mutations. They can have the most varied effects on the expression pattern in the affected tissue, such as, e.g., underexpression or overexpression, but also expression of shortened genes. Several such changes due to these mutation cascades can ultimately lead to malignant degeneration. The complexity of these relationships makes an experimental approach very difficult.

[0005] A database that consists of so-called ESTs is used to look for tumor-related candidate genes, i.e., genes that can be regarded as the cause or the result of malignant degeneration of normal human tissue. ESTs (expressed sequence tags) are sequences of cDNAs, i.e., mRNAs transcribed in reverse, therefore molecules that reflect gene expression. The EST sequences are determined for normal and degenerated tissue. These databases are offered to some extent commercially by various companies. The ESTs of the LifeSeq database, which is used here, are generally between 150 and 350 nucleotides long. They represent a pattern that is unmistakable for a certain gene, although this gene is normally very much longer (>2000 nucleotides). By comparison of the expression patterns of normal and tumor tissue, ESTs can be identified that are important for tumor formation and proliferation (see FIG. 1). There is, however, the following problem: Since the EST sequences found can belong to different regions of an unknown gene due to different constructions of cDNA libraries, in this case a completely incorrect ratio of the occurrence of these ESTs in the respective tissue would arise. This would only be noticed when the complete gene is known and thus ESTs can be assigned to the same gene.

[0006] It has now been found that this error possibility can be reduced if all ESTs from the respective tissue type are assembled beforehand, before the expression patterns are compared to one another. Therefore, overlapping ESTs of the same gene were combined into longer sequences (see FIG. 1, FIG. 2a and FIG. 3). This lengthening and thus coverage of an essentially larger gene area in each of the respective bases are intended to largely avoid the above-described error. Since there were no existing software products for this purpose, programs for assembling genomic sections were employed which were used modified and to which our own programs were added. A flowchart of the assembly procedure is shown in FIG. 2b1-2b4.

[0007] Nucleic acid sequences Seq. ID No. 3, 4, 6, 7, 10, 12, 13, 15, 17-24, 26, 27, 29, 31-34, 36, 37, 39, 40, 44-53; 142, 144-164 which play a part as candidate genes in prostate cancer have now been found.

[0008] Nucleic acid sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 are of special interest.

[0009] The invention thus relates to nucleic acid sequences that code a gene product or a part thereof, comprising

[0010] a) a nucleic acid sequence selected from the group of nucleic acid sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164.

[0011] b) an allelic variation of the nucleic acid sequences named under a) or

[0012] c) a nucleic acid sequence that is complementary to the nucleic acid sequences named under a) or b).

[0013] The invention furthermore relates to a nucleic acid sequence according to one of the sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 or a complementary or allelic version thereof and the nucleic acid sequences thereof that have 90% to 95% homology to a human nucleic acid sequence.

[0014] The invention also relates to nucleic acid sequences Seq. ID No. 3-53; 142, 144-164, which are expressed elevated in the prostate tumor tissue.

[0015] The invention furthermore relates to nucleic acid sequences comprising part of the aforementioned nucleic acid sequences in such a sufficient amount that they hybridize with sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164.

[0016] The nucleic acid sequences according to the invention generally have a length of at least 50 to 2000 bp, preferably a length of at least 150 to 1700 bp.

[0017] With the partial sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 according to the invention, expression cassettes can also be built using current process practice, whereby on the cassette at least one of the nucleic acid sequences according to the invention is combined with at least one control or regulator sequence known to one skilled in the art, such as, e.g., a suitable promoter. The sequences according to the invention can be inserted in a sense or antisense orientation.

[0018] A large number of expression cassettes or vectors and promoters, which can be used, are known in the literature.

[0019] Expression cassettes or vectors are defined as the following: 1. bacterial, such as, e.g., phagescript, pBs, ΦX174, pBluescript SK, pBs KS, pNH8a, pNH16a, pNH18a, pNH46a (Stratagene), pTrc99A, pKK223-3, pKK233-3, pDR540, pRIT5 (Pharmacia), 2. eukaryotic, such as, e.g., pWLneo, pSV2cat, pOG44, pXT1, pSG (Stratagene), pSVK3, pBPV, pMSG, pSVL (Pharmacia).

[0020] A control or regulatory sequence is defined as suitable promotors. Here two preferred vectors are the pKK232-8 and the PCM7 vector. In particular the following promoters are intended: lacI, lacZ, T3, T7, gpt, lambda PR, trc, CMV, HSV thymidine-kinase, SV40, LTRs from retrovirus and mouse metallothionein-I.

[0021] The DNA sequences on the expression cassette can code a fusion protein, which comprises a known protein and a bioactive polypeptide fragment.

[0022] The expression cassettes are likewise the subject matter of this invention.

[0023] The nucleic acid fragments according to the invention can be used to produce full-length genes. The obtainable genes are likewise the subject matter of this invention.

[0024] The invention also relates to the use of the nucleic acid sequences according to the invention and the gene fragments obtainable from use.

[0025] The nucleic acid sequences according to the invention can be moved into host cells with suitable vectors in which as the heterologous part the genetic information which is expressed and which is contained on the nucleic acid fragments is located.

[0026] The host cells containing the nucleic acid fragments are likewise the subject matter of this invention.

[0027] Suitable host cells are, e.g., prokaryotic cell systems such as E. coli or eukaryotic cell systems such as animal or human cells or yeasts.

[0028] The nucleic acid sequences according to the invention can be used in the sense or antisense form.

[0029] Production of polypeptides or their fragments is done by cultivation of the host cells according to current cultivation methods and subsequent isolation and purification of the peptides or fragments, likewise using current methods. The invention furthermore relates to nucleic acid sequences, which code at least a partial sequence of a bioactive polypeptide.

[0030] Furthermore, this invention relates to polypeptide partial sequences, so-called ORF (open-reading-frame) peptides according to the sequence protocols Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199.

[0031] The invention furthermore relates to polypeptide sequences that have at least 80% homology, especially 90% homology, to the polypeptide partial sequences according to the invention of Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199.

[0032] The invention also relates to antibodies that are directed against a polypeptide or a fragment, which are coded by the nucleic acids of sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 according to the invention.

[0033] Antibodies are defined especially as monoclonal antibodies.

[0034] The invention also relates to phage display proteins, which are directed against a polypeptide or a fragment, and which are coded by the nucleic acids of sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 according to the invention.

[0035] The polypeptides of sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 according to the invention can also be used as tools for finding active agents against prostate cancer; this is likewise the subject matter of this invention.

[0036] Likewise the subject matter of this invention is the use of nucleic acid sequences according to sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 for expression of polypeptides, which can also be used as tools for finding active agents against prostate cancer.

[0037] The invention also relates to the use of the found polypeptide partial sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 as pharmaceutical agents in gene therapy for treatment of prostate cancer, or to produce a pharmaceutical agent for treatment of prostate cancer.

[0038] The invention also relates to pharmaceutical agents that contain at least one polypeptide partial sequence of Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199.

[0039] The nucleic acid sequences found according to the invention can also be genomic or mRNA sequences.

[0040] The invention also relates to genomic genes, their promoters, enhancers, silencers, exon structure, intron structure and their splice variants, obtainable from cDNAs of sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 and their use together with suitable regulatory elements, such as suitable promoters and/or enhancers.

[0041] With the nucleic acids according to the invention (cDNA sequences), genomic BAC, PAC and Cosmid libraries are screened and specifically human clones are isolated via complementary base pairing (hybridization). The BAC, PAC and Cosmid clones isolated in this way are hybridized using fluorescence-in-situ hybridization on metaphase chromosomes and the corresponding chromosome sections on which the corresponding genomic genes lie are identified. BAC, PAC and Cosmid clones are sequenced in order to clarify the corresponding genomic genes in their complete structure (promoters, enhancers, silencers, exons and introns). BAC, PAC and Cosmid clones can be used as independent molecules for gene transfer (see FIG. 5).

[0042] The invention also relates to BAC, PAC and Cosmid clones containing functional genes and their chromosomal localization according to sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 for use as vehicles for gene transfer.

Meanings of Technical Terms and Abbreviations
Nucleic acids = Nucleic acids in this invention are defined as:
                mRNA, partial cDNA, full-length cDNA and genomic
                genes (chromosomes).
ORF =           Open Reading Frame, a defined sequence of amino
                acids that can be derived from the cDNA sequence.
Contig =        A set of DNA sequences that can be combined as a
                result of very great similarities into one
                sequence (consensus).
Singleton =     A contig that contains only one sequence.
Module =        Domain of a protein with a defined sequence that
                represents one structural unit and that occurs in
                different proteins
N =             selectively the nucleotide A, T, G or C
X =             selectively one of the 20 naturally occurring
                amino acids

[0043] Explanation of the Alignment Parameters

[0044] minimal initial match=minimal initial identity area

[0045] maximum pads per read=maximum number of insertions

[0046] maximum percent mismatch=maximum deviation in %

EXPLANATION OF FIGURES

[0047] FIG. 1 shows a systematic gene search in the Incyte LifeSeq database.

[0048] FIG. 2 a shows the principle of EST assembling

[0049] FIG. 2b1-2b4 shows the entire principle of EST assembling

[0050] FIG. 3 shows the in-silico subtraction of gene expression in different tissues

[0051] FIG. 4 a shows the determination of tissue-specific expression via electronic Northern

[0052] FIG. 4 b shows the electronic Northern

[0053] FIG. 5 shows the isolation of genomic BAC and PAC clones.

[0054] The following examples explain the production of the nucleic acid sequences according to the invention without limiting the invention to these examples and nucleic acid sequences.

EXAMPLE 1

Search for Tumor-Related Candidate Genes

[0055] First, all ESTs of the corresponding tissue from the LifeSeq database (from October 1997) were extracted. They were then assembled by means of the GAP4 program of the Staden package with the parameters 0% mismatch, 8 pads per read and a minimal match of 20. The sequences (fails) not recorded in the GAP4 database were assembled first at 1% mismatch and then again at 2% mismatch with the database. Consensus sequences were computed from the contigs of the database, which consisted of more than one sequence (see FIG. 2a and 2b1-2b4).

[0056] The singletons of the database, which consisted of only one sequence, were re-assembled at 2% mismatch with the sequences not recorded in the GAP4 database. In turn, for the contigs the consensus sequences were determined. All other ESTs were re-assembled at 4% mismatch. The consensus sequences were extracted once again and finally assembled with the previous consensus sequences and the singletons and the sequences not recorded in the database at 4% mismatch. The consensus sequences were formed and used with the singletons and fails as the initial basis for tissue comparisons. This procedure ensured that among the parameters used all sequences represented gene regions independent of one another.

[0057] FIG. 2b1-2b4 illustrates the lengthening of the prostate tumor ESTs.

[0058] The sequences of the respective tissue assembled in this way were then compared to one another by means of the same program (see FIG. 3). To do this, first, all sequences of the first tissue were input into the database. (Therefore it was important that they were independent of one another).

[0059] Then all sequences of the second tissue were compared to all those of the first. The result was sequences that were specific to the first or the second tissue as well as those which occurred in both. In the latter, the ratio of the frequency of occurrence in the respective tissue was evaluated.

[0060] All sequences that occurred more than four times in one of the compared tissues in each case and all that occurred at least five times as often in one of the two tissues were further studied. These sequences were subjected to an electronic Northern (see Example 2.1), by which the distribution in all tumor and normal tissues was studied (see FIG. 4a and FIG. 4b). The relevant candidates were then lengthened using all Incyte ESTs and all ESTs of public databases (see example 3). Then the sequences and their translation into possible proteins were compared to all nucleotide and protein databases, and studied for possible regions that code for proteins.

EXAMPLE 2

Algorithm for Identification and Lengthening of Partial cDNA Sequences with Altered Expression Pattern

[0061] An algorithm for finding overexpressed or underexpressed genes will be explained below. The individual steps are also summarized in a flowchart for the sake of clarity (see FIG. 4b).

[0062] 2.1. Electronic Northern Blot

[0063] By means of a standard program for homology search, e.g., BLAST (Altschul, S. F., Gish W., Miller, W., Myers, E. W. and Lipman, D. J. (1990) J. Mol. Biol. 215, 403-410), BLAST2 (Altschul S. F., Madden, T. L., Schaeffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Research 25 3389-3402) or FASTA (Pearson, W. R. and Lipman, D. J. (1988) Proc. Natl. Acad. Sci. USA 85 2444-2448) the homologous sequences in different EST libraries (private or public) arranged by tissues were determined for a partial DNA sequence S, e.g., an individual EST or a contig of ESTs. The (relative or absolute) tissue-specific occurrence frequencies of this partial sequence S which were determined in this way are called electronic Northern Blot.

[0064] 2.1.1

[0065] Analogously to the procedure described under 2.1, the EST of the sequence Seq. ID No. 36 was found which occurs 5× more heavily in prostate tumor tissue than in the corresponding normal tissue.

[0066] The possible function of this gene region relates to the glutamate-binding subunit of the NMDA receptor.

[0067] The result is as follows:

	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0465	0.0204	2.2731	0.4399
Breast	0.0373	0.0283	1.3172	0.7592
Ovary	0.0091	0.0078	1.1686	0.8557
Endocrine	0.0292	0.0163	1.7861	0.5599
tissue
Gastrointestinal	0.0039	0.0286	0.1357	7.3686
Brain	0.0195	0.0350	0.5564	1.7973
Hematopoetic	0.0112	0.0000	undef	0.0000
Skin	0.0249	0.0000	undef	0.0000
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0064	0.0137	0.4624	2.1624
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0324	0.0142	2.2824	0.4381
Stomach-	0.0097	0.0307	0.3150	3.1748
esophagus
Muscle-	0.0069	0.0000	undef	0.0000
skeleton
Kidneys	0.0059	0.0274	0.2171	4.6066
Pancreas	0.0076	0.0166	0.4571	2.1876
Penis	0.0150	0.0800	0.1872	5.3424
Prostate	0.0071	0.0341	0.2097	4.7677
Uterus	0.0066	0.0000	undef	0.0000
Breast-	0.0036
hyperplasia
Small intestine	0.0062
Prostatic	0.0208
hyperplasia
Seminal vesicles	0.0089
Sensory organs	0.0000
White blood cells	0.0131
		FETUS
		% freq.
	Development	0.0000
	Gastrointenstinal	0.0092
	Brain	0.0313
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0111
	Kidneys	0.0124
	Prostate	0.0249
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0748
	Ovary uterus	0.0388
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0244
	Hematopoetic	0.0057
	Skin muscle	0.0032
	Testicles	0.0156
	Lungs	0.0000
	Nerves	0.0131
	Prostate	0.0256
	Sensory organs	0.0077

[0068] 2.1.3

[0069] Analogously to the procedure described under 2.1, the EST of the sequence Seq. ID No. 39 was found which occurs 4.5× more heavily in prostate tumor tissue than in the corresponding normal tissue.

[0070] The possible function of this gene region relates to protein control (protein trafficking) in the endoplasmatic reticulum (ER)

[0071] The result is as follows:

	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0051	0.9092	1.0998
Breast	0.0067	0.0022	3.0579	0.3270
Ovary	0.0091	0.0026	3.5059	0.2852
Endocrine	0.0036	0.0054	0.6698	1.4930
tissue
Gastrointestinal	0.0058	0.0095	0.6107	1.6375
Brain	0.0034	0.0033	1.0321	0.9689
Hematopoetic	0.0056	0.0000	undef	0.0000
Skin	0.0050	0.0000	undef	0.0000
Hepatic	0.0099	0.0000	undef	0.0000
Heart	0.0021	0.0000	undef	0.0000
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0062	0.0047	1.3168	0.7594
Stomach	0.0193	0.0000	undef	0.0000
esophagus
Muscle-	0.0051	0.0060	0.8565	1.1675
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0038	0.0055	0.6857	1.4584
Penis	0.0000	0.0000	undef	undef
Prostate	0.0024	0.0106	0.2237	4.4697
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small	0.0093
intestine
Prostatic	0.0089
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0026
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointenstinal	0.0062
	Brain	0.0000
	Hematopoetic	0.0079
	Heart blodd vessels	0.0000
	Lungs	0.0074
	Kidneys	0.0247
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0091
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0162
	Testicles	0.0078
	Lungs	0.0082
	Nerves	0.0020
	Prostate	0.0128
	Sensory organs	0.0000

[0072] 2.1.4

[0073] Analogously to the procedure described under 2.1, the EST of the sequence Seq. ID No. 40 was found which occurs 8× more heavily in prostate tumor tissue than in the corresponding normal tissue.

[0074] The possible function of this gene region relates to the regulation of protein kinase.

[0075] The result is as follows:

	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0120	0.0763	0.1573	6.3588
Ovary	0.0608	0.0234	2.5969	0.3851
Endocrine	0.0073	0.0245	0.2977	3.3593
tissue
Gastrointestinal	0.0872	0.1000	0.8724	1.1462
Brain	0.0017	0.0000	undef	0.0000
Hematopoetic	0.0014	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0149	0.0388	0.3826	2.6139
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0050	0.0355	0.1405	7.1196
Stomach	0.0000	0.0230	0.0000	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0166	0.0000	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0119	0.0958	0.1243	8.0455
Uterus	0.0017	0.0214	0.0774	12.9263
Breast-	0.0073
hyperplasia
Small-	0.0436
intestine
Prostatic	0.0119
hyperplasia
Seminal-	0.0089
vesicles
Sensory organs	0.0470
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointenstinal	0.0247
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0205
	Endocrine tissue	0.0000
	Fetal	0.0052
	Gastrointestinal	0.0366
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0321
	Sensory organs	0.0000

[0076] The following northerns were also found in a similar procedure:

[0077]

Electronic Northern Blot for SEQ. ID. NO: 3
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0128	0.3637	2.7495
Breast	0.0293	0.0087	3.3637	0.2973
Ovary	0.0122	0.0416	0.2922	3.4228
Endocrine	0.0201	0.0245	0.8186	1.2216
tissue
Gastrointestinal	0.0252	0.0571	0.4411	2.2673
Brain	0.0161	0.0131	1.2257	0.8159
Hematopoetic	0.0084	0.1135	0.0739	13.5274
Skin	0.0099	0.0000	undef	0.0000
Hepatic	0.0000	0.0388	0.0000	undef
Heart	0.0180	0.0000	undef	0.0000
Testicles	0.0122	0.0000	undef	0.0000
Lungs	0.0162	0.0189	0.8559	1.1683
Stomach-	0.0000	0.0153	0.0000	undef
esophogas
Muscle-	0.0069	0.0000	undef	0.0000
skeleton
Kidneys	0.0149	0.0342	0.4342	2.3033
Pancreas	0.0265	0.0276	0.9599	1.0417
Penis	0.0180	0.0267	0.6739	1.4840
Prostate	0.0048	0.0149	0.3196	3.1288
Uterus	0.0066	0.0142	0.4642	2.1544
Breast-	0.0291
hyperplasia
Small-	0.0093
intestine
Prostate-	0.0089
hyperplasia
Seminal-	0.0178
vesicles
Sensory organs	0.0000
White blood	0.0148
cells
		FETUS
		% freq.
	Development	0.0307
	Gastrointestinal	0.0062
	Brain	0.0375
	Hematopoetic	0.0079
	Heart blood vessels	0.0164
	Lungs	0.0037
	Kidneys	0.0062
	Prostate	0.0499
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0064
	Gastrointestinal	0.0244
	Hematopoetic	0.0114
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0328
	Nerves	0.0120
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 4
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0153	0.3031	3.2995
Breast	0.0027	0.0044	0.6116	1.6351
Ovary	0.0030	0.0026	1.1686	0.8557
Endocrine-	0.0018	0.0082	0.2233	4.4791
tissue
Gastrointestinal	0.0000	0.0048	0.0000	undef
Brain	0.0000	0.0099	0.0000	undef
Hematopoetic	0.0070	0.0000	undef	0.0000
Skin	0.0050	0.0000	undef	0.0000
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0042	0.0000	undef	0.0000
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0037	0.0024	1.5801	0.6329
Stomach-	0.0097	0.0000	undef	0.0000
esophagus
Muscle-	0.0034	0.0120	0.2855	3.5025
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0019	0.0055	0.3428	2.9168
Penis	0.0000	0.0267	0.0000	undef
Prostate	0.0048	0.0192	0.2486	4.0228
Uterus	0.0083	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0267
vesicles
Sensory-organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood	0.0000
	vessels
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0068
	Endocrine tissue	0.0000
	Fetal	0.0006
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0082
	Nerves	0.0040
	Prostate	0.0256
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 6
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0026	1.8185	0.5499
Breast	0.0027	0.0000	undef	0.0000
Ovary	0.0000	0.0078	0.0000	undef
Endocrine	0.0000	0.0027	0.0000	undef
tissue
Gastrointestinal	0.0039	0.0000	undef	0.0000
Brain	0.0025	0.0000	undef	0.0000
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0193	0.0077	2.5198	0.3968
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0059	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0024	0.0170	0.1398	7.1516
Uterus	0.0066	0.0000	undef	0.0000
Breast-	0.0036
hyperplasia
Small-	0.0000
Intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0124
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 7
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0153	0.0000	undef
Breast	0.0027	0.0109	0.2446	4.0878
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0036	0.0027	1.3396	0.7465
tissue
Gastrointestinal	0.0097	0.0000	undef	0.0000
Brain	0.0008	0.0011	0.7741	1.2918
Hematopoetic	0.0028	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0099	0.0129	0.7651	1.3069
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0019	0.0055	0.3428	2.9168
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0036
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0062
	Brain	0.0063
	Hematopoetic	0.0000
	Heart blood vessels	0.0041
	Lungs	0.0037
	Kidneys	0.0124
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0029
	Gastrointestinal	0.0000
	Hematopoetic	0.0228
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0010
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 10
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0093	0.0051	1.8185	0.5499
Breast	0.0027	0.0000	undef	0.0000
Ovary	0.0000	0.0026	0.0000	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0039	0.0000	undef	0.0000
Brain	0.0076	0.0066	1.1612	0.8612
Hematopoetic	0.0042	0.0000	undef	0.0000
Skin	0.0050	0.0000	undef	0.0000
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0011	0.0275	0.0385	25.9489
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0047	0.0000	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0030	0.0000	undef	0.0000
Pancreas	0.0038	0.0055	0.6857	1.4584
Penis	0.0000	0.0000	undef	undef
Prostate	0.0048	0.0106	0.4475	2.2349
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small-	0.0156
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0089
vesicles
Sensory organs	0.0118
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0031
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0160
	Endocrine tissue	0.0000
	Fetal	0.0058
	Gastrointestinal	0.0000
	Hematopoetic	0.0114
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0060
	Prostate	0.0000
	Sensory organs	0.0155
Electronic Northern Blot for SEQ. ID. NO: 12
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0128	0.3637	2.7495
Breast	0.0080	0.0022	3.6695	0.2725
Ovary	0.0061	0.0026	2.3372	0.4279
Endocrine-	0.0036	0.0082	0.4465	2.2395
tissue
Gastrointestinal	0.0058	0.0048	1.2214	0.8187
Brain	0.0025	0.0077	0.3318	3.0142
Hematopoetic	0.0084	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0042	0.0137	0.3083	3.2436
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0050	0.0071	0.7023	1.4239
Stomach-	0.0097	0.0077	1.2599	0.7937
esophagus
Muscle-	0.0017	0.0300	0.0571	17.5127
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0057	0.0055	1.0285	0.9723
Penis	0.0000	0.0267	0.0000	undef
Prostate	0.0024	0.0170	0.1398	7.1516
Uterus	0.0066	0.0000	undef	0.0000
Breast-	0.0036
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0119
hyperplasia
Seminal-	0.0267
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0031
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood-	0.0041
	vessels
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0068
	Endocrine tissue	0.0245
	Fetal	0.0035
	Gastrointestinal	0.0122
	Hematopoetic	0.0114
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0164
	Nerves	0.0070
	Prostate	0.0256
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 13
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0077	0.0000	undef
Breast	0.0200	0.0240	0.8340	1.1991
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0146	0.0191	0.7655	1.3064
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0008	0.0000	undef	0.0000
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0089	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0124
	Prostate	0.0000
	Sensory organs	0.0419
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0175
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 15
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0128	0.3637	2.7495
Breast	0.0027	0.0087	0.3058	3.2702
Ovary	0.0000	0.0052	0.0000	undef
Endocrine-	0.0073	0.0245	0.2977	3.3593
tissue
Gastrointestinal	0.0019	0.0048	0.4071	2.4562
Brain	0.0127	0.0208	0.6111	1.6363
Hematopoetic	0.0098	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0129	0.0000	undef
Heart	0.0127	0.0000	undef	0.0000
Testicles	0.0061	0.0234	0.2612	3.8288
Lungs	0.0112	0.0047	2.3702	0.4219
Stomach-	0.0000	0.0077	0.0000	undef
esophagus
Muscle-	0.0051	0.0000	undef	0.0000
skeleton
Kidneys	0.0238	0.0068	3.4733	0.2879
Pancreas	0.0095	0.0055	1.7142	0.5834
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0071	0.0277	0.2581	3.8738
Uterus	0.0017	0.0071	0.2321	4.3088
Breast-	0.0145
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0178
hyperplasia
Seminal-	0.0356
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0063
	Hematopoetic	0.0079
	Heart blood vessels	0.0041
	Lungs	0.0111
	Kidneys	0.0185
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Ovary uterus	0.0205
	Endocrine tissue	0.0490
	Fetal	0.0017
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0130
	Testicles	0.0156
	Lungs	0.0000
	Nerves	0.0020
	Prostate	0.0128
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 17
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0011	0.0000	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0030	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0079
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0006
	Gastrointestinal	0.0122
	Hematopoetic	0.0057
	Skin muscle	0.0032
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0040
	Prostate	0.0000
	Sensory organs	0.0077
Electronic Northern Blot for SEQ. ID. NO: 18
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0183	0.0000	undef	0.0000
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0085	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0156
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 19
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0022	0.0000	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0008	0.0000	undef	0.0000
Hematopoetic	0.0028	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 20
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0102	0.4546	2.1996
Breast	0.0000	0.0000	undef	undef
Ovary	0.0091	0.0000	undef	0.0000
Endocrine-	0.0036	0.0054	0.6698	1.4930
tissue
Gastrointestinal	0.0000	0.0048	0.0000	undef
Brain	0.0017	0.0044	0.3871	2.5836
Hematopoetic	0.0070	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0065	0.0000	undef
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0050	0.0024	2.1069	0.4746
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0089	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0043	0.0000	undef
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0073
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0035
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0062
	Brain	0.0125
	Hematopoetic	0.0039
	Heart blood vessels	0.0000
	Lungs	0.0037
	Kidneys	0.0124
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0204
	Ovary uterus	0.0068
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0040
	Prostate	0.0192
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 21
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0043	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 22
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0011	0.0000	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0000
	Hematopoetic	0.0057
	Skin muscle	0.0032
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 23
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0149	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0059
hyperplasia
Seminal	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 24
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0040	0.0000	undef	0.0000
Ovary	0.0030	0.0052	0.5843	1.7114
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0019	0.0000	undef	0.0000
Brain	0.0000	0.0011	0.0000	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0065	0.0000	undef
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0122	0.0000	undef	0.0000
Lungs	0.0025	0.0000	undef	0.0000
Stomach-	0.0000	0.0077	0.0000	undef
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0149	0.0000	undef	0.0000
Pancreas	0.0019	0.0000	undef	0.0000
Penis	0.0000	0.0000	undef	undef
Prostate	0.0048	0.0106	0.4475	2.2349
Uterus	0.0017	0.0071	0.2321	4.3088
Breast-	0.0036
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0154
	Gastrointestinal	0.0031
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0000
	Lungs	0.0037
	Kidneys	0.0062
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Ovary uterus	0.0046
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0000
	Hematopoetic	0.0057
	Skin muscle	0.0032
	Testicles	0.0078
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0128
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 26
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 27
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0026	0.0000	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0037	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0068	0.0000	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0059
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0192
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 29
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0027	0.0000	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0106	0.0000	undef
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 31
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0000	undef	0.0000
Breast	0.0027	0.0044	0.6116	1.6351
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0018	0.0027	0.6698	1.4930
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0042	0.0088	0.4838	2.0669
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0050	0.0000	undef	0.0000
Heart	0.0021	0.0137	0.1541	6.4872
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0120	0.0000	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0166	0.0000	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0000	0.0128	0.0000	undef
Uterus	0.0017	0.0071	0.2321	4.3088
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0059
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0154
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0157
	Heart blood vessels	0.0041
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0249
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Ovary uterus	0.0091
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0060
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 33
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0026	0.0000	undef
Breast	0.0013	0.0000	undef	0.0000
Ovary	0.0030	0.0078	0.3895	2.5671
Endocrine-	0.0000	0.0027	0.0000	undef
tissue
Gastrointestinal	0.0019	0.0000	undef	0.0000
Brain	0.0017	0.0000	undef	0.0000
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0000	0.0234	0.0000	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0000	0.0068	0.0000	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0000	0.0064	0.0000	undef
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate	0.0000
hyperplasia
Seminal	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0000
	Hematopoetic	0.0057
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0050
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 34
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0077	0.0000	undef
Breast	0.0067	0.0065	1.0193	0.9811
Ovary	0.0122	0.0052	2.3372	0.4279
Endocrine-	0.0073	0.0000	undef	0.0000
tissue
Gastrointestinal	0.0019	0.0048	0.4071	2.4562
Brain	0.0102	0.0033	3.0964	0.3230
Hematopoetic	0.0028	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0050	0.0065	0.7651	1.3069
Heart	0.0011	0.0000	undef	0.0000
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0025	0.0000	undef	0.0000
Stomach-	0.0097	0.0153	0.6300	1.5874
esophagus
Muscle-	0.0086	0.0060	1.4275	0.7005
skeleton
Kidneys	0.0030	0.0137	0.2171	4.6066
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0000	0.0128	0.0000	undef
Uterus	0.0033	0.0142	0.2321	4.3088
Breast-	0.0000
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0059
hyperplasia
Seminal-	0.0000
Sensory organs	0.0235
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0062
	Brain	0.0563
	Hematopoetic	0.0118
	Heart blood vessels	0.0082
	Lungs	0.0111
	Kidneys	0.0124
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0544
	Ovary uterus	0.0091
	Endocrine tissue	0.0979
	Fetal	0.0058
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0097
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0161
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 37
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0027	0.0000	undef	0.0000
Ovary	0.0030	0.0000	undef	0.0000
Endocrine	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0025	0.0011	2.3223	0.4306
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0117	0.0000	undef
Lungs	0.0087	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0024	0.0128	0.1864	5.3637
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0154
	Gastrointestinal	0.0031
	Brain	0.0063
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0037
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0140
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0076
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0097
	Testicles	0.0000
	Lungs	0.0082
	Nerves	0.0030
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 44
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0128	0.0000	undef
Breast	0.0013	0.0044	0.3058	3.2702
Ovary	0.0030	0.0052	0.5843	1.7114
Endocrine	0.0018	0.0054	0.3349	2.9861
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0033	0.0000	undef
Hematopoetic	0.0000	0.0378	0.0000	undef
Skin	0.0050	0.1693	0.0294	34.0525
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0064	0.0000	undef	0.0000
Testicles	0.0061	0.0117	0.5224	1.9144
Lungs	0.0025	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0086	0.0000	undef	0.0000
skeleton
Kidneys	0.0089	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0024	0.0128	0.1864	5.3637
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0000
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0052
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0041
	Lungs	0.0037
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0041
	Gastrointestinal	0.0122
	Hematopoetic	0.0114
	Skin muscle	0.0065
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0030
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 45
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0179	0.0000	undef
Breast	0.0013	0.0044	0.3058	3.2702
Ovary	0.0030	0.0026	1.1686	0.8557
Endocrine	0.0018	0.0000	undef	0.0000
tissue
Gastrointestinal	0.0097	0.0000	undef	0.0000
Brain	0.0000	0.0022	0.0000	undef
Hematopoetic	0.0014	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0000	undef	0.0000
Stomach-	0.0000	0.0077	0.0000	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0068	0.0000	undef
Pancreas	0.0000	0.0055	0.0000	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0024	0.0447	0.0533	18.7729
Uterus	0.0000	0.0071	0.0000	undef
Breast-	0.0109
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0089
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0037
	Kidneys	0.0062
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0082
	Nerves	0.0010
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 46
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0051	0.0000	undef
Breast	0.0053	0.0153	0.3495	2.8614
Ovary	0.0091	0.0182	0.5008	1.9967
Endocrine-	0.0055	0.0191	0.2870	3.4837
tissue
Gastrointestinal	0.0252	0.0238	1.0585	0.9447
Brain	0.0068	0.0153	0.4423	2.2607
Hematopoetic	0.0042	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0099	0.0065	1.5303	0.6535
Heart	0.0000	0.0412	0.0000	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0025	0.0095	0.2634	3.7971
Stomach-	0.0290	0.0000	undef	0.0000
esophagus
Muscle-	0.0103	0.0060	1.7130	0.5838
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0038	0.0221	0.1714	5.8337
Penis	0.0060	0.0000	undef	0.0000
Prostate	0.0262	0.0532	0.4922	2.0317
Uterus	0.0033	0.0142	0.2321	4.3088
Breast-	0.0036
hyperplasia
Small-	0.0125
intestine
Prostate-	0.0119
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0009
cells
		FETUS
		% freq.
	Development	0.0154
	Gastrointestinal	0.0031
	Brain	0.0125
	Hematopoetic	0.0000
	Heart blood vessels	0.0041
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Ovary uterus	0.0137
	Endocrine tissue	0.0000
	Fetal	0.0070
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0097
	Testicles	0.0000
	Lungs	0.0082
	Nerves	0.0110
	Prostate	0.0321
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 47
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0051	0.9092	1.0998
Breast	0.0080	0.0087	0.9174	1.0901
Ovary	0.0061	0.0000	undef	0.0000
Endocrine-	0.0073	0.0054	1.3396	0.7465
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0051	0.0088	0.5806	1.7224
Hematopoetic	0.0070	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0021	0.0000	undef	0.0000
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0062	0.0024	2.6336	0.3797
Stomach-	0.0000	0.0077	0.0000	undef
esophagus
Muscle-	0.0086	0.0000	undef	0.0000
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0057	0.0000	undef	0.0000
Penis	0.0090	0.0000	undef	0.0000
Prostate	0.0048	0.0128	0.3729	2.6818
Uterus	0.0083	0.0071	1.1604	0.8618
Breast-	0.0000
hyperplasia
Small-	0.0125
intestine
Prostate-	0.0059
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0061
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0031
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0041
	Lungs	0.0037
	Kidneys	0.0185
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0068
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0328
	Nerves	0.0080
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 48
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0153	0.0000	undef
Breast	0.0040	0.0044	0.9174	1.0901
Ovary	0.0000	0.0104	0.0000	undef
Endocrine-	0.0018	0.0000	undef	0.0000
tissue
Gastrointestinal	0.0019	0.0095	0.2036	4.9124
Brain	0.0000	0.0055	0.0000	undef
Hematopoetic	0.0098	0.0000	undef	0.0000
Skin	0.0050	0.0000	undef	0.0000
Hepatic	0.0000	0.0194	0.0000	undef
Heart	0.0021	0.0000	undef	0.0000
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0012	0.0047	0.2634	3.7971
Stomach-	0.0097	0.0077	1.2599	0.7937
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0057	0.0000	undef	0.0000
Penis	0.0000	0.0267	0.0000	undef
Prostate	0.0048	0.0298	0.1598	6.2576
Uterus	0.0033	0.0071	0.4642	2.1544
Breast-	0.0000
hyperplasia
Small-	0.0031
intestine
Prostate-	0.0238
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0026
cells
		FETUS
		% freq.
	Development	0.0154
	Gastrointestinal	0.0154
	Brain	0.0063
	Hematopoetic	0.0000
	Heart blood vessels	0.0041
	Lungs	0.0111
	Kidneys	0.0000
	Prostate	0.0499
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0160
	Endocrine tissue	0.0000
	Fetal	0.0041
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0030
	Prostate	0.0128
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 49
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0026	0.0000	undef
Breast	0.0067	0.0065	1.0193	0.9811
Ovary	0.0061	0.0052	1.1686	0.8557
Endocrine-	0.0055	0.0027	2.0093	0.4977
tissue
Gastrointestinal	0.0019	0.0048	0.4071	2.4562
Brain	0.0008	0.0044	0.1935	5.1673
Hematopoetic	0.0042	0.0000	undef	0.0000
Skin	0.0050	0.0000	undef	0.0000
Hepatic	0.0099	0.0000	undef	0.0000
Heart	0.0064	0.0275	0.2312	4.3248
Testicles	0.0061	0.0117	0.5224	1.9144
Lungs	0.0087	0.0071	1.2290	0.8137
Stomach-	0.0097	0.0077	1.2599	0.7937
esophagus
Muscle-	0.0086	0.0060	1.4275	0.7005
skeleton
Kidneys	0.0059	0.0068	0.8683	1.1517
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0533	0.0000	undef
Prostate	0.0024	0.0170	0.1398	7.1516
Uterus	0.0066	0.0142	0.4642	2.1544
Breast-	0.0000
hyperplasia
Small-	0.0062
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0118
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0092
	Brain	0.0000
	Hematopoetic	0.0118
	Heart blood vessels	0.0204
	Lungs	0.0185
	Kidneys	0.0247
	Prostate	0.0249
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0111
	Gastrointestinal	0.0000
	Hematopoetic	0.0057
	Skin muscle	0.0194
	Testicles	0.0000
	Lungs	0.0328
	Nerves	0.0020
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 50
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0000	undef	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0000	0.0000	undef	undef
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0024	0.0255	0.0932	10.7274
Uterus	0.0000	0.0000	undef	undef
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 51
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0000	0.0077	0.0000	undef
Breast	0.0000	0.0022	0.0000	undef
Ovary	0.0000	0.0000	undef	undef
Endocrine	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0000	0.0000	undef	undef
Brain	0.0008	0.0033	0.2580	3.8754
Hematopoetic	0.0000	0.0000	undef	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0065	0.0000	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0061	0.0000	undef	0.0000
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0097	0.0000	undef	0.0000
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Penis	0.0000	0.0267	0.0000	undef
Prostate	0.0048	0.0192	0.2486	4.0228
Uterus	0.0017	0.0142	0.1160	8.6176
Breast-	0.0000
hyperplasia
Small-	0.0000
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0000
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0031
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0000
	Lungs	0.0000
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0082
	Nerves	0.0000
	Prostate	0.0128
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 52
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0046	0.0077	0.6062	1.6497
Breast	0.0027	0.0022	1.2232	0.8176
Ovary	0.0030	0.0026	1.1686	0.8557
Endocrine	0.0000	0.0000	undef	undef
tissue
Gastrointestinal	0.0039	0.0000	undef	0.0000
Brain	0.0076	0.0022	3.4835	0.2871
Hematopoetic	0.0042	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0065	0.0000	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0071	0.0000	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0034	0.0060	0.5710	1.7513
skeleton
Kidneys	0.0030	0.0000	undef	0.0000
Pancreas	0.0000	0.0055	0.0000	undef
Penis	0.0000	0.0000	undef	undef
Prostate	0.0048	0.0149	0.3196	3.1288
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0036
hyperplasia
Small-	0.0062
intestine
Prostate-	0.0059
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0062
	Brain	0.0000
	Hematopoetic	0.0039
	Heart blood vessels	0.0041
	Lungs	0.0037
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0244
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0000
	Nerves	0.0070
	Prostate	0.0064
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 53
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0093	0.0128	0.7274	1.3748
Breast	0.0053	0.0022	2.4463	0.4088
Ovary	0.0030	0.0026	1.1686	0.8557
Endocrine-	0.0109	0.0082	1.3396	0.7465
tissue
Gastrointestinal	0.0039	0.0048	0.8143	1.2281
Brain	0.0042	0.0153	0.2765	3.6171
Hematopoetic	0.0042	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0050	0.0000	undef	0.0000
Heart	0.0064	0.0000	undef	0.0000
Testicles	0.0061	0.0117	0.5224	1.9144
Lungs	0.0075	0.0024	3.1603	0.3164
Stomach-	0.0193	0.0153	1.2599	0.7937
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0137	0.0000	undef
Pancreas	0.0057	0.0110	0.5143	1.9446
Penis	0.0030	0.0000	undef	0.0000
Prostate	0.0048	0.0106	0.4475	2.2349
Uterus	0.0017	0.0000	undef	0.0000
Breast-	0.0145
hyperplasia
Small-	0.0062
intestine
Prostate-	0.0000
hyperplasia
Seminal-	0.0089
Sensory organs	0.0000
White blood	0.0044
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0123
	Brain	0.0063
	Hematopoetic	0.0000
	Heart blood vessels	0.0123
	Lungs	0.0037
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Ovary uterus	0.0160
	Endocrine tissue	0.0000
	Fetal	0.0140
	Gastrointestinal	0.0122
	Hematopoetic	0.0057
	Skin muscle	0.0130
	Testicles	0.0156
	Lungs	0.0082
	Nerves	0.0090
	Prostate	0.0128
	Sensory organs	0.0000
Electronic Northern Blot for SEQ. ID. NO: 142
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
Bladder	0.0093	0.0026	3.6370	0.2750
Breast	0.0067	0.0131	0.5096	1.9621
Ovary	0.0122	0.0130	0.9349	1.0696
Endocrine-	0.0036	0.0027	1.3396	0.7465
tissue
Gastrointestinal	0.0058	0.0048	1.2214	0.8187
Brain	0.0161	0.0044	3.6770	0.2720
Hematopoetic	0.0056	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0099	0.0065	1.5303	0.6535
Heart	0.0117	0.0000	undef	0.0000
Testicles	0.0000	0.0117	0.0000	undef
Lungs	0.0075	0.0189	0.3950	2.5314
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0069	0.0060	1.1420	0.8756
skeleton
Kidneys	0.0000	0.0068	0.0000	undef
Pancreas	0.0057	0.0000	undef	0.0000
Penis	0.0000	0.0267	0.0000	undef
Prostate	0.0024	0.0085	0.2797	3.5758
Uterus	0.0033	0.0142	0.2321	4.3088
Breast-	0.0036
hyperplasia
Small-	0.0125
intestine
Prostate-	0.0030
hyperplasia
Seminal-	0.0000
vesicles
Sensory organs	0.0000
White blood	0.0017
cells
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0092
	Brain	0.0125
	Hematopoetic	0.0000
	Heart blood vessels	0.0041
	Lungs	0.0148
	Kidneys	0.0000
	Prostate	0.0000
	Sensory organs	0.0140
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Ovary uterus	0.0023
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0000
	Hematopoetic	0.0114
	Skin muscle	0.0000
	Testicles	0.0000
	Lungs	0.0410
	Nerves	0.0090
	Prostate	0.0192
	Sensory organs	0.0000
Electronic Northern for SEQ. ID: 144
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphoma	0.0025	0.0000	undef	0.0000
Bladder	0.0039	0.0141	0.2766	3.6156
Breast	0.0062	0.0056	1.0959	0.9125
Large-	0.0057	0.0028	2.0184	0.4955
intestine
Small-	0.0000	0.0107	0.0000	undef
intestine
Ovary	0.0059	0.0024	2.4887	0.4018
Endocrine-	0.0016	0.0142	0.1132	8.8363
tissue
Brain	0.0023	0.0140	0.1658	6.0318
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0000	0.0063	0.0000	undef
Heart	0.0061	0.0137	0.4430	2.2572
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0029	0.0074	0.3947	2.5338
Stomach-	0.0145	0.0000	undef	0.0000
esophagus
Muscle-	0.0017	0.0185	0.0928	10.7785
skeleton
Kidneys	0.0067	0.0048	1.3927	0.7180
Pancreas	0.0083	0.0055	1.4958	0.6685
Prostate	0.0066	0.0143	0.4604	2.1719
T lymphoma	0.0000	0.0000	undef	undef
Uterus	0.0103	0.0138	0.7497	1.3339
White blood	0.0007	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0000
Seminal-	0.0211
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0056
	Brain	0.0063
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0071
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0303
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0354
	Endocrine tissue	0.0245
	Fetal	0.0029
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0125
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0131
	Kidneys_t	0.0000
	Ovary_Uterus	0.0225
	Prostate_n	0.0182
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 145
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0025	0.0000	undef	0.0000
Bladder	0.0390	0.1151	0.3387	2.9527
Breast	0.0132	0.0014	9.3932	0.1065
Large	0.0498	0.0114	4.3731	0.2287
intestine
Small	0.0165	0.0000	undef	0.0000
intestine
Ovary	0.0000	0.0072	0.0000	undef
Endocrine	0.0016	0.0124	0.1293	7.7318
tissue
Brain	0.0278	0.0150	1.8568	0.5386
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0127	0.0000	undef
Heart	0.0000	0.0550	0.0000	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0156	0.0000	undef	0.0000
Stomach-	0.0145	0.0064	2.2671	0.4411
esophagus
Muscle-	0.0017	0.0074	0.2319	4.3114
skeleton
Kidneys	0.0067	0.0048	1.3927	0.7180
Pancreas	0.0248	0.0552	0.4487	2.2285
Prostate	0.0349	0.0638	0.5463	1.8304
T lymphoma	0.0076	0.0000	undef	0.0000
Uterus	0.0089	0.0000	undef	0.0000
White blood	0.0157	0.0000	undef	0.0000
cells
Hematopoetic	0.0080
Penis	0.0027
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0056
	Brain	0.0000
	Hematopoetic	0.0079
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0124
	Placenta	0.0182
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0203
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0000
	Hematopoetic	0.0257
	Skin muscle	0.0000
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0010
	Kidneys_t	0.0000
	Ovary_Uterus	0.0090
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 146
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0075	0.0000	undef	0.0000
Bladder	0.0078	0.0094	0.8297	1.2052
Breast	0.0044	0.0042	1.0437	0.9581
Large-	0.0038	0.0000	undef	0.0000
intestine
Small-	0.0165	0.0213	0.7730	1.2937
intestine
Ovary	0.0030	0.0048	0.6222	1.6073
Endocrine-	0.0000	0.0018	0.0000	undef
tissue
Brain	0.0081	0.0070	1.1605	0.8617
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0093	0.0063	1.4649	0.6826
Heart	0.0030	0.0275	0.1108	9.0287
Testicles	0.0040	0.0059	0.6786	1.4737
Lungs	0.0000	0.0037	0.0000	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0090	0.0000	undef	0.0000
Pancreas	0.0050	0.0055	0.8975	1.1142
Prostate	0.0047	0.0091	0.5168	1.9350
T lymphoma	0.0051	0.0075	0.6762	1.4788
Uterus	0.0015	0.0046	0.3213	3.1125
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0053
Penis	0.0054
Seminal-	0.0070
vesicles
Sensory organs	0.0118
		FETUS
		% freq.
	Development	0.0139
	Gastrointestinal	0.0028
	Brain	0.0000
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0061
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0253
	Endocrine tissue	0.0000
	Fetal	0.0064
	Gastrointestinal	0.0000
	Hematopoetic	0.0257
	Skin muscle	0.0000
	Testicles_n	0.0084
	Testicles_t	0.0000
	Lungs_n	0.0195
	Lungs_t	0.0000
	Nerves	0.0070
	Kidneys_t	0.0000
	Ovary_Uterus	0.0158
	Prostate_n	0.0000
	Sensory organs	0.0155
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 147
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0025	0.0000	undef	0.0000
Bladder	0.0039	0.0141	0.2766	3.6156
Breast	0.0062	0.0028	2.1917	0.4563
Large-	0.0057	0.0028	2.0184	0.4955
intestine
Small-	0.0000	0.0107	0.0000	undef
intestine
Ovary	0.0059	0.0024	2.4887	0.4018
Endocrine-	0.0016	0.0106	0.1509	6.6272
tissue
Brain	0.0046	0.0080	0.5803	1.7234
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0041	0.0137	0.2954	3.3858
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0039	0.0055	0.7016	1.4253
Stomach-	0.0145	0.0000	undef	0.0000
esophagus
Muscle-	0.0017	0.0185	0.0928	10.7785
skeleton
Kidneys	0.0045	0.0048	0.9285	1.0770
Pancreas	0.0066	0.0055	1.1966	0.8357
Prostate	0.0057	0.0130	0.4341	2.3036
T lymphoma	0.0000	0.0000	undef	undef
Uterus	0.0074	0.0046	1.6064	0.6225
White blood	0.0014	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0000
Seminal-	0.0211
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0056
	Brain	0.0000
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0071
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0121
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0304
	Endocrine tissue	0.0245
	Fetal	0.0046
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0209
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0141
	Kidneys_t	0.0000
	Ovary_Uterus	0.0203
	Prostate_n	0.0182
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 148
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0125	0.0000	undef	0.0000
Bladder	0.0039	0.0141	0.2766	3.6156
Breast	0.0079	0.0141	0.5636	1.7743
Large-	0.0038	0.0057	0.6728	1.4864
intestine
Small-	0.0027	0.0107	0.2577	3.8812
intestine
Ovary	0.0000	0.0095	0.0000	undef
Endocrine-	0.0161	0.0231	0.6964	1.4359
tissue
Brain	0.0156	0.0229	0.6812	1.4681
Skin	0.0110	0.0000	undef	0.0000
Hepatic	0.0000	0.0190	0.0000	undef
Heart	0.0132	0.0000	undef	0.0000
Testicles	0.0080	0.0118	0.6786	1.4737
Lungs	0.0097	0.0055	1.7540	0.5701
Stomach-	0.0000	0.0064	0.0000	undef
esophagus
Muscle-	0.0086	0.0000	undef	0.0000
skeleton
Kidneys	0.0246	0.0048	5.1067	0.1958
Pancreas	0.0116	0.0055	2.0941	0.4775
Prostate	0.0104	0.0221	0.4682	2.1360
T lymphoma	0.0152	0.0000	undef	0.0000
Uterus	0.0089	0.0092	0.9638	1.0375
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0107
Penis	0.0054
Seminal-	0.0493
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0125
	Hematopoetic	0.0079
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0036
	Lungs	0.0108
	Adrenal gland	0.0000
	Kidneys	0.0309
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0557
	Endocrine tissue	0.0735
	Fetal	0.0023
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0130
	Testicles_n	0.0125
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0020
	Kidneys_t	0.0000
	Ovary_Uterus	0.0248
	Prostate_n	0.0121
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 149
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0000	0.0000	undef	undef
Breast	0.0000	0.0042	0.0000	undef
Large-	0.0000	0.0028	0.0000	undef
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0032	0.0000	undef	0.0000
tissue
Brain	0.0000	0.0010	0.0000	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0010	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0045	0.0000	undef	0.0000
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0019	0.0039	0.4823	2.0732
T lymphoma	0.0051	0.0000	undef	0.0000
Uterus	0.0000	0.0000	undef	undef
White blood	0.0014	0.0000	undef	0.0000
cells
Hematopoetic	0.0000
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0079
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0244
	Hematopoetic	0.0000
	Skin muscle	0.0032
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0050
	Kidneys_t	0.0000
	Ovary_Uterus	0.0045
	Prostate_n	0.0000
	Sensory organs	0.0077
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 150
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0100	0.0000	undef	0.0000
Bladder	0.0117	0.0094	1.2446	0.8035
Breast	0.0035	0.0014	2.5048	0.3992
Large-	0.0038	0.0028	1.3456	0.7432
intestine
Small-	0.0055	0.0000	undef	0.0000
intestine
Ovary	0.0059	0.0048	1.2443	0.8036
Endocrine-	0.0032	0.0053	0.6036	1.6568
tissue
Brain	0.0029	0.0070	0.4145	2.4127
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0190	0.0000	undef
Heart	0.0051	0.0000	undef	0.0000
Testicles	0.0040	0.0000	undef	0.0000
Lungs	0.0039	0.0055	0.7016	1.4253
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0067	0.0000	undef	0.0000
Pancreas	0.0017	0.0000	undef	0.0000
Prostate	0.0038	0.0052	0.7235	1.3821
T lymphoma	0.0101	0.0149	0.6762	1.4788
Uterus	0.0015	0.0046	0.3213	3.1125
White blood	0.0048	0.0000	undef	0.0000
cells
Hematopoetic	0.0094
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0028
	Brain	0.0125
	Hematopoetic	0.0079
	Skin	0.0000
	Hepatic	0.0000
	Heart blood	0.0000
	vessels
	Lungs	0.0072
	Adrenal gland	0.0000
	Kidneys	0.0185
	Placenta	0.0061
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0204
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0152
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0000
	Hematopoetic	0.0257
	Skin muscle	0.0000
	Testicles_n	0.0042
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0100
	Kidneys_t	0.0000
	Ovary_Uterus	0.0090
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 151
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0000	0.0023	0.0000	undef
Breast	0.0000	0.0000	undef	undef
Large-	0.0000	0.0000	undef	undef
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0071	0.0000	undef
tissue
Brain	0.0000	0.0010	0.0000	undef
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0009	0.0039	0.2412	4.1464
T lymphoma	0.0000	0.0075	0.0000	undef
Uterus	0.0015	0.0000	undef	0.0000
White blood	0.0007	0.0000	undef	0.0000
cells
Hematopoetic	0.0000
Penis	0.0000
Seminal-vesicles	0.0000
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0035
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0032
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0010
	Kidneys_t	0.0000
	Ovary_Uterus	0.0000
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 152
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0000	0.0047	0.0000	undef
Breast	0.0009	0.0014	0.6262	1.5969
Large-	0.0038	0.0000	undef	0.0000
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0000	0.0024	0.0000	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Brain	0.0006	0.0010	0.5803	1.7234
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0049	0.0000	undef	0.0000
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0017	0.0000	undef	0.0000
Prostate	0.0075	0.0039	1.9294	0.5183
T lymphoma	0.0000	0.0075	0.0000	undef
Uterus	0.0015	0.0000	undef	0.0000
White blood	0.0000	0.0000	undef	undef
cells
Hematopoetic	0.0000
Penis	0.0027
Seminal-	0.0070
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0028
	Brain	0.0063
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0062
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0010
	Kidneys_t	0.0000
	Ovary_Uterus	0.0000
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 153
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0075	0.0000	undef	0.0000
Bladder	0.0078	0.0000	undef	0.0000
Breast	0.0026	0.0028	0.9393	1.0646
Large-	0.0000	0.0000	undef	undef
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0016	0.0000	undef	0.0000
tissue
Brain	0.0041	0.0110	0.3693	2.7082
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0046	0.0000	undef	0.0000
Heart	0.0020	0.0137	0.1477	6.7715
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0010	0.0018	0.5262	1.9004
Stomach	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0000	0.0074	0.0000	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0166	0.0000	undef
Prostate	0.0028	0.0078	0.3618	2.7643
T lymphoma	0.0025	0.0000	undef	0.0000
Uterus	0.0015	0.0046	0.3213	3.1125
White blood	0.0000	0.0000	undef	undef
cells
Hematopoetic	0.0000
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0139
	Gastrointestinal	0.0000
	Brain	0.0063
	Hematopoetic	0.0157
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0036
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0249
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0068
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0152
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0060
	Kidneys_t	0.0000
	Ovary Uterus	0.0113
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 154
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0075	0.0000	undef	0.0000
Bladder	0.0000	0.0023	0.0000	undef
Breast	0.0018	0.0014	1.2524	0.7985
Large-	0.0019	0.0000	undef	0.0000
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0030	0.0072	0.4148	2.4110
Endocrine-	0.0000	0.0095	0.0000	undef
tissue
Brain	0.0018	0.0000	undef	0.0000
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0010	0.0000	undef	0.0000
Testicles	0.0000	0.0118	0.0000	undef
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0034	0.0000	undef	0.0000
skeleton
Kidneys	0.0000	0.0048	0.0000	undef
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0009	0.0039	0.2412	4.1465
T lymphoma	0.0025	0.0000	undef	0.0000
Uterus	0.0015	0.0000	undef	0.0000
White blood	0.0014	0.0000	undef	0.0000
cells
Hematopoetic	0.0053
Penis	0.0027
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0000
	Brain	0.0000
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0017
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0042
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0060
	Kidneys_t	0.0000
	Ovary_Uterus	0.0000
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 155
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0100	0.0000	undef	0.0000
Bladder	0.0000	0.0117	0.0000	undef
Breast	0.0088	0.0098	0.8946	1.1179
Large-	0.0019	0.0028	0.6728	1.4864
intestine
Small-	0.0027	0.0000	undef	0.0000
intestine
Ovary	0.0119	0.0048	2.4886	0.4018
Endocrine-	0.0064	0.0019	3.3917	0.2948
tissue
Brain	0.0205	0.0060	3.4255	0.2919
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0046	0.0063	0.7324	1.3653
Heart	0.0030	0.0000	undef	0.0000
Testicles	0.0040	0.0000	undef	0.0000
Lungs	0.0049	0.0037	1.3155	0.7602
Stomach-	0.0072	0.0192	0.3778	2.6472
esophagus
Muscle-	0.0103	0.0037	2.7833	0.3593
skeleton
Kidneys	0.0022	0.0096	0.2321	4.3085
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0066	0.0130	0.5065	1.9745
T lymphoma	0.0000	0.0075	0.0000	undef
Uterus	0.0046	0.0138	0.3368	2.9694
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0080
Seminal-	0.0070
vesicles
Sensory organs	0.0235
		FETUS
		% freq.
	Development	0.0139
	Gastrointestinal	0.0083
	Brain	0.0626
	Hematopoetic	0.0118
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0107
	Lungs	0.0108
	Adrenal gland	0.0254
	Kidneys	0.0124
	Placenta	0.0061
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0544
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0051
	Endocrine tissue	0.0979
	Fetal	0.0058
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0194
	Testicles_n	0.0167
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0201
	Kidneys_t	0.0000
	Ovary_Uterus	0.0090
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 156
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0025	0.0000	undef	0.0000
Bladder	0.0039	0.0141	0.2766	3.6156
Breast	0.0044	0.0098	0.4473	2.2357
Large-	0.0019	0.0057	0.3364	2.9727
intestine
Small-	0.0110	0.0107	1.0306	0.9703
intestine
Ovary	0.0030	0.0119	0.2489	4.0182
Endocrine-	0.0032	0.0089	0.3621	2.7613
tissue
Brain	0.0017	0.0040	0.4352	2.2978
Skin	0.0037	0.0789	0.0466	21.4787
Hepatic	0.0000	0.0063	0.0000	undef
Heart	0.0152	0.0000	undef	0.0000
Testicles	0.0120	0.0237	0.5089	1.9650
Lungs	0.0039	0.0037	1.0524	0.9502
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0086	0.0000	undef	0.0000
skeleton
Kidneys	0.0090	0.0000	undef	0.0000
Pancreas	0.0017	0.0055	0.2992	3.3427
Prostate	0.0038	0.0117	0.3216	3.1098
T lymphoma	0.0101	0.0224	0.4508	2.2182
Uterus	0.0030	0.0092	0.3213	3.1125
White blood	0.0123	0.0607	0.2029	4.9287
cells
Hematopoetic	0.0040
Penis	0.0054
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0028
	Brain	0.0000
	Hematopoetic	0.0079
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0142
	Lungs	0.0072
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0061
	Prostate	0.0000
	Sensory organs	0.0126
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0070
	Gastrointestinal	0.0122
	Hematopoetic	0.0000
	Skin muscle	0.0065
	Testicles_n	0.0042
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0060
	Kidneys_t	0.0000
	Ovary Uterus	0.0023
	Prostate_n	0.0121
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 157
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0025	0.0000	undef	0.0000
Bladder	0.0000	0.0235	0.0000	undef
Breast	0.0035	0.0070	0.5010	1.9961
Large-	0.0134	0.0000	undef	0.0000
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0030	0.0048	0.6222	1.6073
Endocrine-	0.0032	0.0000	undef	0.0000
tissue
Brain	0.0006	0.0040	0.1451	6.8935
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0000	0.0000	undef	undef
Heart	0.0010	0.0275	0.0369	27.0862
Testicles	0.0000	0.0000	undef	undef
Lungs	0.0010	0.0000	undef	0.0000
Stomach-	0.0072	0.0064	1.1335	0.8822
esophagus
Muscle-	0.0017	0.0000	undef	0.0000
skeleton
Kidneys	0.0022	0.0048	0.4642	2.1540
Pancreas	0.0000	0.0055	0.0000	undef
Prostate	0.0123	0.0456	0.2687	3.7211
T lymphoma	0.0000	0.0000	undef	undef
Uterus	0.0015	0.0046	0.3213	3.1125
White blood	0.0000	0.0000	undef	undef
cells
Hematopoetic	0.0013
Penis	0.0000
Seminal-	0.0070
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0028
	Brain	0.0000
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0072
	Adrenal gland	0.0000
	Kidneys	0.0124
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0051
	Endocrine tissue	0.0000
	Fetal	0.0000
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0032
	Testicles_n	0.0042
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0040
	Kidneys_t	0.0000
	Ovary_Uterus	0.0045
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 158
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0039	0.0047	0.8297	1.2052
Breast	0.0079	0.0112	0.7045	1.4195
Large-	0.0287	0.0142	2.0184	0.4955
intestine
Small-	0.0192	0.0000	undef	0.0000
intestine
Ovary	0.0059	0.0167	0.3555	2.8128
Endocrine-	0.0064	0.0177	0.3621	2.7613
tissue
Brain	0.0087	0.0140	0.6217	1.6085
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0139	0.0063	2.1973	0.4551
Heart	0.0020	0.0412	0.0492	20.3146
Testicles	0.0040	0.0000	undef	0.0000
Lungs	0.0039	0.0129	0.3007	3.3256
Stomach-	0.0217	0.0000	undef	0.0000
esophagus
Muscle-	0.0120	0.0037	3.2472	0.3080
skeleton
Kidneys	0.0045	0.0048	0.9285	1.0770
Pancreas	0.0050	0.0221	0.2244	4.4570
Prostate	0.0254	0.0469	0.5426	1.8428
T lymphoma	0.0051	0.0075	0.6762	1.4788
Uterus	0.0030	0.0092	0.3213	3.1125
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0054
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0278
	Gastrointestinal	0.0056
	Brain	0.0125
	Hematopoetic	0.0039
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0036
	Lungs	0.0000
	Adrenal gland	0.0507
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0253
	Endocrine tissue	0.0000
	Fetal	0.0075
	Gastrointestinal	0.0244
	Hematopoetic	0.0000
	Skin muscle	0.0097
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0141
	Kidneys_t	0.0000
	Ovary_Uterus	0.0158
	Prostate_n	0.0243
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 159
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0075	0.0000	undef	0.0000
Bladder	0.0000	0.0141	0.0000	undef
Breast	0.0026	0.0028	0.9393	1.0646
Large-	0.0077	0.0057	1.3456	0.7432
intestine
Small-	0.0027	0.0107	0.2577	3.8812
intestine
Ovary	0.0030	0.0095	0.3111	3.2146
Endocrine-	0.0064	0.0018	3.6214	0.2761
tissue
Brain	0.0000	0.0060	0.0000	undef
Skin	0.0073	0.0000	undef	0.0000
Hepatic	0.0000	0.0190	0.0000	undef
Heart	0.0020	0.0000	undef	0.0000
Testicles	0.0000	0.0059	0.0000	undef
Lungs	0.0010	0.0037	0.2631	3.8007
Stomach-	0.0072	0.0064	1.1335	0.8822
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0067	0.0048	1.3927	0.7180
Pancreas	0.0050	0.0000	undef	0.0000
Prostate	0.0123	0.0260	0.4703	2.1264
T lymphoma	0.0101	0.0149	0.6762	1.4788
Uterus	0.0044	0.0092	0.4819	2.0750
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0120
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0139
	Gastrointestinal	0.0194
	Brain	0.0063
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0260
	Heart blood vessels	0.0071
	Lungs	0.0108
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0121
	Prostate	0.0499
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0608
	Endocrine tissue	0.0000
	Fetal	0.0075
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0000
	Lungs_t	0.0000
	Nerves	0.0030
	Kidneys_t	0.0000
	Ovary_Uterus	0.0293
	Prostate_n	0.0061
	Sensory organs	0.0387
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 160
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0125	0.0000	undef	0.0000
Bladder	0.0000	0.0023	0.0000	undef
Breast	0.0044	0.0056	0.7828	1.2775
Large-	0.0019	0.0028	0.6728	1.4864
intestine
Small-	0.0055	0.0000	undef	0.0000
intestine
Ovary	0.0059	0.0048	1.2443	0.8036
Endocrine-	0.0048	0.0071	0.6790	1.4727
tissue
Brain	0.0017	0.0050	0.3482	2.8723
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0093	0.0000	undef	0.0000
Heart	0.0071	0.0275	0.2584	3.8695
Testicles	0.0040	0.0059	0.6786	1.4737
Lungs	0.0097	0.0074	1.3155	0.7601
Stomach-	0.0072	0.0064	1.1335	0.8822
esophagus
Muscle-	0.0069	0.0037	1.8555	0.5389
skeleton
Kidneys	0.0045	0.0048	0.9285	1.0770
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0009	0.0104	0.0904	11.0571
T lymphoma	0.0025	0.0000	undef	0.0000
Uterus	0.0059	0.0092	0.6426	1.5563
White blood	0.0000	0.0000	undef	undef
cells
Hematopoetic	0.0040
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0083
	Brain	0.0000
	Hematopoetic	0.0118
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0178
	Lungs	0.0181
	Adrenal gland	0.0000
	Kidneys	0.0247
	Placenta	0.0061
	Prostate	0.0249
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0110
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0194
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0293
	Lungs_t	0.0000
	Nerves	0.0020
	Kidneys_t	0.0000
	Ovary_Uterus	0.0023
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 161
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0000	0.0070	0.0000	undef
Breast	0.0000	0.0014	0.0000	undef
Large-	0.0000	0.0000	undef	undef
intestine
Small-	0.0000	0.0000	undef	undef
intestine
Ovary	0.0000	0.0000	undef	undef
Endocrine-	0.0000	0.0000	undef	undef
tissue
Brain	0.0006	0.0030	0.1934	5.1701
Skin	0.0037	0.0000	undef	0.0000
Hepatic	0.0000	0.0063	0.0000	undef
Heart	0.0000	0.0000	undef	undef
Testicles	0.0040	0.0000	undef	0.0000
Lungs	0.0000	0.0000	undef	undef
Stomach-	0.0072	0.0000	undef	0.0000
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0000	0.0000	undef	undef
Pancreas	0.0000	0.0000	undef	undef
Prostate	0.0038	0.0117	0.3216	3.1098
T lymphoma	0.0025	0.0000	undef	0.0000
Uterus	0.0015	0.0092	0.1606	6.2251
White blood	0.0000	0.0000	undef	undef
cells
Hematopoetic	0.0000
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0028
	Brain	0.0000
	Hematopoetic	0.0039
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0000
	Lungs	0.0000
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0012
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0000
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0000
	Kidneys_t	0.0000
	Ovary_Uterus	0.0000
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 162
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0075	0.0000	undef	0.0000
Bladder	0.0039	0.0070	0.5532	1.8078
Breast	0.0053	0.0028	1.8786	0.5323
Large-	0.0038	0.0057	0.6728	1.4864
intestine
Small-	0.0082	0.0000	undef	0.0000
intestine
Ovary	0.0030	0.0048	0.6222	1.6073
Endocrine-	0.0016	0.0018	0.9054	1.1045
tissue
Brain	0.0214	0.0030	7.1565	0.1397
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0000	0.0063	0.0000	undef
Heart	0.0030	0.0000	undef	0.0000
Testicles	0.0040	0.0000	undef	0.0000
Lungs	0.0019	0.0092	0.2105	4.7509
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0069	0.0074	0.9278	1.0778
skeleton
Kidneys	0.0022	0.0000	undef	0.0000
Pancreas	0.0017	0.0055	0.2992	3.3427
Prostate	0.0066	0.0143	0.4604	2.1719
T lymphoma	0.0000	0.0000	undef	undef
Uterus	0.0015	0.0046	0.3213	3.1125
White blood	0.0068	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0054
Seminal-	0.0141
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0056
	Brain	0.0000
	Hematopoetic	0.0039
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0036
	Lungs	0.0036
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0000
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0340
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0051
	Endocrine tissue	0.0000
	Fetal	0.0035
	Gastrointestinal	0.0366
	Hematopoetic	0.0000
	Skin muscle	0.0097
	Testicles_n	0.0000
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0201
	Kidneys_t	0.0000
	Ovary_Uterus	0.0045
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 163
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0050	0.0000	undef	0.0000
Bladder	0.0078	0.0117	0.6638	1.5065
Breast	0.0070	0.0028	2.5048	0.3992
Large-	0.0038	0.0028	1.3456	0.7432
intestine
Small-	0.0055	0.0000	undef	0.0000
intestine
Ovary	0.0030	0.0024	1.2443	0.8036
Endocrine-	0.0096	0.0106	0.9054	1.1045
tissue
Brain	0.0046	0.0130	0.3571	2.8005
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0046	0.0000	undef	0.0000
Heart	0.0061	0.0000	undef	0.0000
Testicles	0.0040	0.0059	0.6786	1.4737
Lungs	0.0068	0.0018	3.6835	0.2715
Stomach-	0.0145	0.0064	2.2671	0.4411
esophagus
Muscle-	0.0000	0.0000	undef	undef
skeleton
Kidneys	0.0022	0.0096	0.2321	4.3081
Pancreas	0.0050	0.0110	0.4487	2.2285
Prostate	0.0028	0.0065	0.4341	2.3036
T lymphoma	0.0025	0.0149	0.1691	5.9152
Uterus	0.0030	0.0000	undef	0.0000
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0040
Penis	0.0027
Seminal-	0.0070
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0111
	Brain	0.0063
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0000
	Heart blood vessels	0.0107
	Lungs	0.0036
	Adrenal gland	0.0000
	Kidneys	0.0000
	Placenta	0.0121
	Prostate	0.0000
	Sensory organs	0.0000
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0136
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.0000
	Ovary_t	0.0203
	Endocrine tissue	0.0000
	Fetal	0.0139
	Gastrointestinal	0.0122
	Hematopoetic	0.0257
	Skin muscle	0.0130
	Testicles_n	0.0125
	Testicles_t	0.0000
	Lungs_n	0.0098
	Lungs_t	0.0000
	Nerves	0.0100
	Kidneys_t	0.0000
	Ovary_Uterus	0.0180
	Prostate_n	0.0000
	Sensory organs	0.0000
	White blood cells	0.0000
Electronic Northern for SEQ. ID: 164
	NORMAL	TUMOR	RATIOS
	% freq.	% freq.	N/T	T/N
B_Lymphom	0.0000	0.0000	undef	undef
Bladder	0.0078	0.0023	3.3190	0.3013
Breast	0.0053	0.0126	0.4175	2.3954
Large-	0.0057	0.0057	1.0092	0.9909
intestine
Small-	0.0110	0.0000	undef	0.0000
intestine
Ovary	0.0119	0.0119	0.9955	1.0046
Endocrine-	0.0032	0.0035	0.9054	1.1045
tissue
Brain	0.0174	0.0040	4.3519	0.2298
Skin	0.0000	0.0000	undef	undef
Hepatic	0.0093	0.0063	1.4649	0.6826
Heart	0.0112	0.0000	undef	0.0000
Testicles	0.0120	0.0059	2.0357	0.4912
Lungs	0.0068	0.0148	0.4604	2.1719
Stomach-	0.0000	0.0000	undef	undef
esophagus
Muscle-	0.0069	0.0037	1.8555	0.5389
skeleton
Kidneys	0.0022	0.0048	0.4642	2.1540
Pancreas	0.0066	0.0000	undef	0.0000
Prostate	0.0019	0.0052	0.3618	2.7643
T lymphoma	0.0126	0.0373	0.3381	2.9576
Uterus	0.0030	0.0092	0.3213	3.1125
White blood	0.0027	0.0000	undef	0.0000
cells
Hematopoetic	0.0053
Penis	0.0000
Seminal-	0.0000
vesicles
Sensory organs	0.0000
		FETUS
		% freq.
	Development	0.0000
	Gastrointestinal	0.0083
	Brain	0.0125
	Hematopoetic	0.0000
	Skin	0.0000
	Hepatic	0.0260
	Heart blood vessels	0.0036
	Lungs	0.0181
	Adrenal gland	0.0000
	Kidneys	0.0062
	Placenta	0.0061
	Prostate	0.0000
	Sensory organs	0.0126
		STANDARDIZED/
		SUBTRACTED LIBRARIES
		% freq.
	Breast	0.0000
	Breast_t	0.0000
	Large intestine_t	0.0000
	Ovary_n	0.1595
	Ovary_t	0.0000
	Endocrine tissue	0.0000
	Fetal	0.0035
	Gastrointestinal	0.0000
	Hematopoetic	0.0000
	Skin muscle	0.0065
	Testicles_n	0.0042
	Testicles_t	0.0000
	Lungs_n	0.0293
	Lungs_t	0.0000
	Nerves	0.0090
	Kidneys_t	0.0000
	Ovary_Uterus	0.0023
	Prostate_n	0.0182
	Sensory organs	0.0000
	White blood cells	0.0000

[0078] 2.2. Fisher Test

[0079] In order to decide whether a partial sequence S of a gene occurs significantly more often or less often in a library for normal tissue than in a library for degenerated tissue, Fisher's exact test, a standard statistical process, is carried out (Hays, W. L., (1991) Statistics, Harcourt Brace College Publishers, Fort Worth).

[0080] The null hypothesis reads: The two libraries cannot be distinguished with respect to the frequency of sequences homologous to S. If the null hypothesis can be rejected with high enough certainty, the gene belonging to S is accepted as an advantageous candidate for a cancer gene, and in the next step an attempt is made to achieve lengthening of its sequence.

EXAMPLE 3

Automatic Lengthening of the Partial Sequence

[0081] Automatic lengthening of partial sequence S is completed in three steps:

[0082] 1. Determination of all sequences homologous to S from the total set of available sequences using BLAST.

[0083] 2. Assembling these sequences by means of the standard program GAP4 (Bonfield, J. K., Smith, K. F. and Staden, R. (1995), Nucleic Acids Research 23 4992-4999) (contig formation).

[0084] 3. Computation of a consensus sequence C from the assembled sequences.

[0085] Consensus sequence C will generally be longer than initial sequence S. Its electronic Northern Blot will accordingly deviate from that for S. A repeated Fisher test decides whether the alternative hypothesis of deviation from a uniform expression in the two libraries can be maintained. If this is the case, an attempt is made to lengthen C in the same way as S. This iteration is continued with the consensus sequences Ci (i: iteration index) obtained each time until the alternative hypothesis is rejected (if H0 Exit; truncation criterion I) or until automatic lengthening is no longer possible (while Ci>Ci−1; truncation criterion II).

[0086] In the case of truncation criterion II, with the consensus sequence present after the last iteration, a complete or roughly complete sequence of a gene that can be related to cancer with high statistical certainty is acquired.

[0087] Analogously to the above described examples, the nucleic acid sequences described in Table I from prostate tumor tissue were found.

[0088] Furthermore, for the individual nucleic acid sequences the peptide sequences (ORFs) which are listed in Table II were determined, in which no peptide can be assigned to a few nucleic acid sequences and more than one peptide can be assigned to some nucleic acid sequences. As already mentioned above, both the determined nucleic acid sequences and also the peptide sequences assigned to the nucleic acid sequences are the subject of this invention.

EXAMPLE 4

Mapping of Nucleic Acid Sequences on the Human Genome

[0089] Human genes were mapped using the Stanford G3 Hybrid Panel (Stewart et al., 1997) which is marketed by Research Genetics, Huntsville, Ala. This panel consists of 83 different genomic DNAs of human-hamster hybrid cell lines and allows resolution of 500 kilobases. The hybrid cell lines were obtained by fusion of irradiated diploid human cells with cells of the Chinese hamster. The retention pattern of the human chromosome fragments is determined by means of gene-specific primers in a polymerase chain reaction and is analyzed using software available from the Stanford RH server (http://www.stanford.edu/RH/rhserver_form2. html). This program determines the STS marker which is nearest the desired gene. The corresponding cytogenetic band was determined using the “Mapview” program of the Genome Database (GDB), (http://gdbwww.dkfz-heidelberg.de). In addition to mapping of genes on the human chromosome set by various experimental methods it is possible to determine the location of genes on this by biocomputer methods. To do this, the known program e-PCR was used (Schuler G D (1998) Electronic PCR: Bridging the Gap Between Genome Mapping and Genome Sequencing. Trends Biotechnol 16: 456-459, Schuler G D (1997). Sequence Mapping By Electronic PCR, Genome Res. 7; 541-550). The database used here no longer corresponds to the one cited in the literature, but is a development that includes data from the public database RHdb (http://www.ebi.ac.uk/RHdb/index.html). Analogously to the mapping by the hybrid panels, the results were evaluated with the aforementioned software and the software of the Whitehead Institute (http://carbon.wi.mit.edu:8000/cgi-bin/contig/rhmapper.pl).

EXAMPLE 5

Obtaining Genomic DNA Sequences (BAC Clones)

[0090] The genomic BAC clones containing the corresponding cDNAs (http://www.tree.caltech.edu/; Shizuya, H., B. Birren, U-J. Kim, V. Mancino, T. Slepak, Y. Tachiiri, M. Simon (1992) Proc. Natl. Acad. Sci., USA 89: 8794-8797) were isolated with the procedure of “down-to-the-well”. In this procedure a library consisting of BAC clones (the library covers roughly 3× the human genome) is moved into a certain raster so that the DNA of these clones with a specific PCR can be studied. In doing so “pooling” of the DNA of different BAC clones takes place. Combinatorial analysis makes it possible to determine the clones that contain the desired DNA. By fixing the clones the address of the clones in the library can be determined. This address together with the name of the library which is being used unequivocally fixes the clones and thus the DNA sequence of these clones.

[0091] The following examples explain the successful isolation of the genomic BAC clones without limiting them thereto.

[0092] The libraries used were CITB B and CITB C:

Seq.ID No.	Identified BACs
3	523-P-21
20	446-E-12
33	544-K-9	552-M-9	391-B15	228-G-2
36	420-I-3	395-G-4	489-A14
44	194-A-22	438-F-10	491-A-16
50	423-P-13	327-G-1	221-M-24	197-M-19
51	244-C-10	421-G-19
53	342-M-13	347-N-18
142	353-J-9	383-F-17	404-H-16	416-N-2	501-A-5

[0093]

TABLE 1
							Length of	Seq. ID
						Length of	Claimed	of
Seq.				Cytogenetic	Nearest	Initial EST	Sequence	Initial
ID	Expression	Function	Modules	Localization	Marker	in Bases	in Bases	Sequence
3	elevated in	Human homolog to	Pyropho	10q21.1-	SHGC-36251-	246	1258
	prostate tumors	bovine inorganic	sphatase	q22.1	D10S1428
		pyrophosphatase
4	elevated in	Unknown		2q35	SHGC-32022-	257	894
	prostate tumors				D2S126
6	elevated in	Human homolog to	TBC			225	1017
	prostate tumors	a GTPase activating
		protein from
		Yarrowia lypolytica
7	elevated in	MLN 62	MATH;	17p12-q11.2	D17S798	192	671
	prostate and		TRAF
	breast tumors
10	elevated in	Unknown		1p36.13-	D1S3153-	225	870
	prostate tumors			p36.12	D1S2740
12	elevated in	BCE-1		2q35	SHGC-32022-	215	1312
	prostate tumors				D2S126
13	elevated in	GATA-3		10p15.1	D10S1431-	230	1008
	prostate tumors				SHGC-32335
15	elevated in	Unknown		19p13.3-	D19S854-	193	706
	prostate tumors			P13.2	SHGC-36605
17	in	Unknown		2q33.1-q33.3	SHGC-36529-	246	450
	nonstandardized				D2S374
	or subtracted
	libraries only
	detectable in
	prostate and
	brain tumors
34	elevated in	Unknown		17q11.2	SHGC-2348	386	1563
	prostate tumors
36	ca. 5x more	Homolog to NMDA		8q24.3	AFMA128XH5	298	1557
	heavily in
	prostate tumors
	than in
	corresponding
	normal tissue
37	5x more heavily	Unknown		18q21.1-	D18S831-	213	1381
	in prostate			18q21.33	D18S64
	tumors than in
	corresponding
	normal tissue
39	ca. 4.5x more	Human homolog to		3q22.1-3q23	SHGC-37132-	224	615
	heavily in	Sec61			SHGC-30693
	prostate tumors
	than in
	corresponding
	normal tissue
40	8x more heavily	HUMAN INTESTINAL	trefoil	21q22.3		276	834
	in prostate	TREFOIL FACTOR
	tumors than in	HP1.B
	corresponding
	normal tissue
44	elevated in	Unknown		6q12-p12.1	SHGC-10670-	207	997
	prostate and				SHGC-31710
	skin tumors
45	elevated in	Homolog to human	CATION—	19q13.2-	SHGC-9668-	212	548
	prostate tumors	metastatin 1	CHAN	q13.41	SHGC-30929
			NEL_TRPL
46	elevated in	Unknown		9q21.32-	D9S1120-	241	1448
	prostate tumors			q22.1	D9S1812
47	elevated in	Homolog to a		16p13.3-	D16S521-	165	1163
	prostate tumors	protein kinase C		q24.3	SHGC-2951
		substrate
48	elevated in	Unknown		19q13.2-	NIB1805-WI-	260	906
	prostate tumors			q13.41	9028
49	elevated in	Unknown		2p24.3	D2S1288	259	1222
	prostate tumors
50	elevated in	Unknown				277	649
	prostate tumors
51	elevated in	Unknown				272	1226
	prostate tumors
52	elevated in	Unknown		12q24.22-	D12S1619-	249	1036
	prostate tumors			q24.23	D12S1915
53	elevated in	Homology to the	Ribosomal—	10q11.1-	D10S1571-	228	758
	prostate tumors	family of high	L7A	q23.1	D10S583
		mobility group
		proteins
142	elevated in	Calcyclin-		1q24-25	WI-3733-WI-	317	1663
	prostate tumors	binding protein			5780
144	expressed	Unknown		2q35	SHGC-32022-		2105	4
	2.1719x in the				D2S126
	prostate tumor
	compared to
	normal prostate
	tissue
145	expressed	Human homolog to	TBC				1125	6
	1.8304x in the	a GTPase
	prostate tumor	activating
	compared to	protein from
	normal prostate	Yarrowia
	tissue	lypolytica
146	expressed	Unknown		1p36.l3-	D1S3153-		1490	10
	1.935x in the			p36.12	D1S2740
	prostate tumor
	compared to
	normal prostate
	tissue
147	expressed BCE-1			2q35	SHGC-32022-		1692	12
	2.3036x in the				D2S126
	prostate tumor
	compared to
	normal prostate
	tissue
148	expressed	Unknown		19p13.3-	D19S854-		866	15
	2.1361x in the			p13.2	SHGC-36605
	prostate tumor
	compared to
	normal prostate
	tissue
149	expressed	Unknown		2q33.1-q33.3	SHGC-36529-		992	17
	2.0732x in the				D2S374
	prostate tumor
	compared to
	normal prostate
	tissue
150	expressed	Human homolog to	GAMMA—				1640	20
	1.3821x in the	tyrosine-protein	CARB
	prostate tumor	kinase 1 from	OXYLASE
	compared to	Dictyostelium
	normal prostate	discoideurm
	tissue
151	expressed	Human homolog to	zf-C2H2	16p11.2	SHGC-2727-		974	22
	4.1464x in the	ZPF-29 from mice			SHGC-35326
	prostate tumor
	compared to
	normal prostate
	tissue
152	expressed	Homolog to		15q25.1-	SHGC-30592-		1059	27
	1.9294x in the	DYNANIN-1		q25.3	SHGC-35120
	prostate tumor
	compared to
	normal prostate
	tissue
153	expressed	Unknown		10q21.1-21.3	D10S1688-		2003	31
	2.7643x in the				SHGC-33649
	prostate tumor
	compared to
	normal prostate
	tissue
154	expressed	Human homolog to	HSP70				1130	33
	4.1465x in the	NST-1 from mice
	prostate tumor
	compared to
	normal prostate
	tissue
155	expressed	Phosphatidyl		17q11.2	SHGC-2348		5779	34
	1.9745x. in the	inositol-4-
	prostate tumor	phosphate-5-
	compared to	kinase type 2
	normal prostate	beta
	tissue
156	expressed	Lysophospholipase	ESTERASE	6q12-p12.1	SHGC-10670-		2408	44
	3.1098x in the				SHGC-31710
	prostate tumor
	compared to
	normal prostate
	tissue
157	expressed	Homolog to human	CATION—	19q13.2-	SHGC-9668-		1548	45
	3.7211x in the	metastatin 1	CHANNEL-	q13.41	SHGC-30929
	prostate tumor		TRPL
	compared to
	normal prostate
	tissue
158	expressed	Unknown		9q21.32-	D9S1120-		2319	46
	1.8428x in the			q22.1	D9S1812
	prostate tumor
	compared to
	normal prostate
	tissue
18	elevated in	Unknown		Xq25-28	DXS1062-	233	418
	prostate tumors				DXS9754
19	only in	Homolog to		20q13.2	D20S197-	282	549
	prostate and	inositol			SHGC-33731
	breast tumors	polyphosphate-4-
		phosphatase type
		1 beta
20	elevated in	Unknown				249	999
	prostate tumors
21	elevated in	Unknown		4q31.22-	D4S397-	301	311
	prostate tumors			31.23	D4S2965
22	elevated in	Unknown		16p11.2	SHGC-2727-	231	527
	prostate tumors				SHGC-35326
23	detectable only	Unknown		9q21.31-	SHGC-35114-	224	359
	in prostate			21.32	D9S1122
	tumors
24	elevated in	Unknown		2p11.1-2p12	D2S388-	242	1482
	prostate tumors				D2S2579
26	detectable only	Unknown		2q11.2	D2S2311-	229	316
	in prostate				D2S2886
	tumors
27	elevated in	Homolog to		15q25.1-	SHGC-30592-	209	369
	prostate tumor	DYNAMIN-1		q25.3	SHGC-35120
	and hyperplasia
29	detectable in	Unknown		6q23.1-23.3	D6S1835-	260	591
	normal lung				D6S1569
	tissue, in
	prostate and
	endocrine
	tumors
31	elevated in	Unknown		10q21.1-21.3	D10S1688-	241	1631
	prostate tumors				SHGC-33649
33	elevated in	Human homolog to	HSP70			247	844
	prostate tumors	NST-1 from mice
159	expressed	Unknown		19q13.2-	NIB1805-WI-		1467	48
	2.1264x in the			q13.41	9028
	prostate tumor
	compared to
	normal prostate
	tissue
160	expressed	Unknown		2p24.3	D2S1288		1348	49
	11.0571x in the
	prostate tumor
	compared to
	normal prostate
	tissue
161	expressed	Unknown					1290	51
	3.1098x in the
	prostate tumor
	compared to
	normal prostate
	tissue
162	expressed	Unknown		12q24.22-	D12S1619-		2912	52
	2.1719x in the			q24.23	D12S1915
	prostate tumor
	compared to
	normal prostate
	tissue
163	expressed	Homology to the	Ribosom	10q11.1-	D10S1571-		850	53
	2.3036x in the	family of high	al—	q23.1	D10S583
	prostate tumor	mobility group	L7Ae
	compared to	proteins
	normal prostate
	tissue
164	expressed	Calcyclin-		1q24-25	WI-3733-WI-		2223	142
	2.7643x in the	binding protein			5780
	prostate tumor
	compared to
	normal prostate
	tissue

[0094]

TABLE 2
DNA Sequence	Peptide	Sequence
Seq ID No.	(ORFs)	Seq ID No.
3	57
4	58
6	59	60
7	61
10	64
12	66	67
13	68
15	70	71
17	73	74
18	75
19	76	77
20	78	79
21	80
22	81
23	82
24	83
26	85
27	86
29	87
31	89	90
33
34	92
36	94
37	95
39
40	97
44	101	102	103	104	105
45	106	107	108
46	109	110	111
47	112	113	114
48	115	116	117	118	119	120	121
49	122	123	124	125
50	126	127	128	129
51	130	131	132
52	133	134	135	136	137
53	138	139	140	141
142	143
144	165	166
145	167
146	168	169
147	170	171
148	172	173
149	174	175
150	176	177
151	178
152	179	180
153	181	182
154	183
155	184
156	185
157	186	187
158	188	189
159	190	191
160	192	193
161	194	195
162	196	197
163	198
164	199

[0095] The inventive nucleic acid sequences Seq. ID No. 3, 4, 6, 7, 10, 12, 13, 15, 17-24, 26, 27, 29, 31-34, 36, 37, 39, 40, 44-53; 142 144-164 of the determined candidate genes and the determined amino acid sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 are described in the following sequence protocol.

Claims

1. A nucleic acid sequence that codes a gene product or a part thereof, comprising a) a nucleic acid sequence selected from the group Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 b) an allelic variation of the nucleic acid sequences named under a) or c) a nucleic acid sequence that is complementary to the nucleic acid sequences named under a) or b).

2. A nucleic acid sequence according to one of the sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164, or a complementary or allelic variant thereof.

3. Nucleic acid sequence Seq. ID No. 3, 4, 6, 7, 10, 12, 13, 15, 17-24, 26, 27, 29, 31-34, 36, 37, 39, 40, 44-53; 142, 144-164, characterized in that it is expressed elevated in prostate tumor tissue.

4. BAC, PAC and Cosmid clones containing functional genes and their chromosomal localization according to sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 for use as a vehicle for gene transfer.

5. A nucleic acid sequence according to claims 1 to 4, wherein it has 90% homology to a human nucleic acid sequence.

6. A nucleic acid sequence according to claims 1 to 4, wherein it has 95% homology to a human nucleic acid sequence.

7. A nucleic acid sequence comprising a portion of the nucleic acid sequences named in claims 1 to 6, in such a sufficient amount that they hybridize with the sequences according to claims 1 to 6.

8. A nucleic acid sequence according to claims 1 to 7, wherein the size of the fragment has a length of at least 50 to 2000 bp.

9. A nucleic acid sequence according to claims 1 to 7, wherein the size of the fragment has a length of at least 150 to 1700 bp.

10. A nucleic acid sequence according to one of claims 1 to 9, which codes at least one partial sequence of a bioactive polypeptide.

11. An expression cassette comprising a nucleic acid fragment or a sequence according to one of claims 1 to 9, together with at least one control or regulatory sequence.

12. An expression cassette, comprising a nucleic acid fragment or a sequence according to claim 11, in which the control or regulatory sequence is a suitable promoter.

13. An expression cassette according to one of claims 11 and 12, wherein the DNA sequences located on the cassette code a fusion protein that comprises a known protein and a bioactive polypeptide fragment.

14. Use of nucleic acid sequences according to claims 1 to 10 for producing full-length genes.

15. A DNA fragment, comprising a gene, which can be obtained from an application according to claim 14.

16. Host cell, containing as the heterologous part of its expressible genetic information a nucleic acid fragment according to one of claims 1 to 10.

17. Host cell according to claim 16, wherein it is a prokaryotic or eukaryotic cell system.

18. Host cell according to one of claims 16 or 17, wherein the prokaryotic cell system is E. coli and the eukaryotic cell system is an animal, human or yeast cell system.

19. A process for producing a polypeptide or a fragment, wherein the host cells according to claims 16 to 18 are cultivated.

20. An antibody which is directed against a polypeptide or a fragment, which by the nucleic acids of sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164, which can be obtained according to claim 19.

21. An antibody according to claim 20, wherein it is monoclonal.

22. A protein according to claim 20, wherein it originates from a phage display.

23. Polypeptide partial sequences according to sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199.

24. Polypeptide partial sequences according to claim 22, with at least 80% homology to these sequences.

25. Polypeptide partial sequences according to claim 22, with at least 90% homology to these sequences.

26. Use of polypeptide partial sequences according to sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 as tools for finding active agents against prostate cancer.

27. Use of nucleic acid sequences according to sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164 for expression of polypeptides which can be used as tools for finding active agents against prostate cancer.

28. Use of nucleic acid sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27-29, 31-34, 36, 39, 44 53; 142, 144-164 in sense or antisense form.

29. Use of polypeptide partial sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 as pharmaceutical agents in gene therapy for treatment of prostate cancer.

30. Use of polypeptide partial sequences Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199 to produce a pharmaceutical agent for treatment of prostate cancer.

31. Pharmaceutical agent, containing at least one polypeptide partial sequence Seq. ID No. 57-61, 64, 66-68, 70-71, 73-83, 85-87, 89-90, 92, 94, 95, 97, 101-141, 143 and 165-199.

32. A nucleic acid sequence according to claims 1 to 10, wherein it is a genomic sequence.

33. A nucleic acid sequence according to claims 1 to 10, wherein it is an mRNA sequence.

34. Genomic genes, their promoters, enhancers, silencers, exon structure, intron structure and their splice variants, obtainable from cDNAs of sequences Seq. ID No. 3, 4, 6; 10, 12, 15, 17-24, 27, 29, 31-34, 36, 39, 44-53; 142, 144-164.

35. Use of the genomic genes according to claim 33, together with suitable regulatory elements.

36. Use according to claim 34, wherein the regulatory element is a suitable promoter and/or enhancer.