This invention relates, in general, to an apparatus for implanting a marker, in an animal and, in particular, an identification or sensory marker in a laboratory animal, and methods of producing an apparatus for implanting a marker in an animal.
Various markers can be implanted in an animal, according to the purpose being served. For example, identification markers can include transponders containing information regarding the identity of the animal, and can provide the stored information when scanned by a reader or at predetermined intervals. Another example of markers include markers that can collect information from the animal. For example, the marker can comprise mechanisms to collect physiological data regarding the animal, such as its temperature. Such a marker can be beneficial to monitor the health of the animal. A marker can comprise both of these features as well.
Markers typically comprise a capsule housing the necessary components and is implanted utilizing an apparatus having a sharp cannula. A marker can either be inserted into the cannula during manufacture or by the user prior to implantation. The user typically inserts the sharp end of the cannula containing the marker into the animal and then inserts a pushrod into the opposite end of the cannula, thereby pushing the marker with the pushrod out of the sharp end of the cannula and into the animal.
A currently available apparatus for implanting makers is typically insert molded, wherein a cannula is inserted into a mold for the housing, and the housing is molded around the cannula. However, during the insert molding process of conventional methods, the distal end of the cannula can be damaged, for example, while being inserted into the mold or being removed from the mold. The distal end of the cannula is typically angled and has a tip sufficiently sharp enough to pierce the skin of the animal to initiate implantation of the marker. Therefore, damaging the sharp distal tip can be detrimental to the performance of the implanting apparatus and thus can result in numerous products or components thereof being discarded during production.
In light of shortcomings described above, it is desirable to provide an implantation apparatus and methods of producing and/or assembling an implantation apparatus for implanting a marker that can overcome the discrepancies of the conventional implantation apparatus and methods of production thereof known in the art.
Generally speaking, the present invention is directed toward an apparatus for implanting a marker in an animal and methods of producing an apparatus for implanting a marker. It is to be understood that the term “producing” includes forming, assembling, combining, etc., and is not limited to any particular process or manner. Additionally, it is to be understood that the term “animal” includes mammals, such as humans, rodents, etc., as well as fish, reptiles, etc. More specifically, in accordance with an embodiment of the invention, an apparatus for implanting a marker in an animal comprises a cannula and a housing that can be assembled after the independent production of the housing and the cannula components.
In accordance with one embodiment of the invention, an implanting apparatus comprises a cannula having a sharp distal end and a blunt proximal end and a housing, wherein the housing is molded independently of the cannula. The blunt proximal end of the cannula can be inserted into the distal end of the housing, which preferably comprises an adhesive insertion portion. An effective amount of adhesive can thereafter be inserted into the adhesive insertion portion, thereby securing the cannula in place with respect to the housing.
Accordingly, it is an object of the invention to provide a method for producing an apparatus for implanting a marker having a housing that is produced independently of a cannula and combined thereafter.
Additionally, it is an object of the invention to provide a method for assembling an apparatus for implantation having a housing that is injection molded independently of a cannula and combined thereafter.
Other objects and features of the present invention will become apparent from the following detailed description, considered in conjunction with the accompanying drawing figure. It is to be understood, however, that the drawings are designed solely for the purpose of illustration and not as a definition of the limits of the invention, for which reference should be made to the appended claims.
For a fuller understanding of the invention, reference is had to the following description, taken in connection with the accompanying drawings, in which:
Reference is made to
As shown in more detail in
An embodiment of housing 100 is shown in
Bore 111 preferably comprises distal portion 112 and a proximal portion 113, wherein distal portion 112 is further away from the user than proximal portion 113 when implanter 10 is properly held by the user. As shown in
Most preferably, as shown more clearly in
Alternatively, adhesive receiving space 114 can be defined by the amount of adhesive inserted into bore 111 of housing 100. A preferred embodiment of the invention includes a plurality of ribs 123 in bore 111 which preferably assist in aligning cannula 200 concentrically with bore 111. More preferably, bore 111 comprises about three ribs 123.
In accordance with a preferred embodiment of the invention, an effective amount of an adhesive is inserted into adhesive receiving space 114 through an adhesive aperture 115 which preferably extends through a gripping structure 130 into adhesive receiving space 114 of bore 111. Preferably, the adhesive is inserted after cannula 200 is inserted into housing 100 and most preferably, while cannula 200 is mechanically pushed against shoulder 122, which can help maintain cannula 200 connected to marker entrance 119 and prevent the adhesive from flowing into marker entrance 119. The inserted adhesive preferably fills the area formed inside adhesive receiving space 114 and outside cannula 200. The adhesive preferably surrounds the outer circumference of cannula 200, and extends within adhesive receiving space 114 until the adhesive substantially fills adhesive receiving space 114, thereby securing cannula 200 to tubular member 110 of housing 100. Most preferably, as discussed above, distal ring 116 and proximal ring 117 prevent the adhesive from extending beyond distal ring 116 and proximal ring 117, thereby containing the adhesive to a concentrated area and preventing the adhesive from exiting tubular member 110.
Referring to
Proximal member 160 preferably includes a thumb support 162 beneficially positioned relative to gripping surface 131, the combination of which preferably provides a relatively stable and easy handling of implanter 10. For example, the user's index and middle fingers can engage one gripping surface 131 each, and the user's thumb can engage thumb support 162, thereby creating a stable handle on implanter 10 when the fingers and the thumb apply opposing forces, more specifically, in direction Y on gripping surfaces 131 and direction X on thumb support 162, respectively. Most preferably, gripping surface 131 and thumb support 162 comprise concave shapes for ergonomically engaging a finger or thumb.
Channel 150 preferably can receive marker 20 and permits marker 20 to move within the length of channel 150. Channel 150 preferably can also receive a portion of a pushrod 300, more preferably a rod 310 of pushrod 300, which preferably can be used to facilitate the insertion of marker 20 into cannula 200 and also to facilitate the ejection of marker 20 out of cannula 200 into the animal. An embodiment of pushrod 300 is illustrated in
In accordance with an embodiment of the invention, pushrod 300 preferably comprises a circumferential pushrod rib 360 which preferably engages the inner surface of cannula bore 230, thereby creating a barrier packaging between cannula bore 230 on the proximal side of marker 20. As defined herein, a barrier packaging permits sterilizing agents in during sterilization and prevents the free movement of air in or out in ambient, thereby assisting in maintaining sterility. Therefore, the sterility of implanter 10 can be maintained until cover pushrod 300 is removed.
In accordance with a preferred embodiment of the invention, pushrod 300 comprises one or more proximal stoppers 350 and one or more corresponding distal stoppers. Proximal member 161 of housing 100 preferably comprises one or more corresponding ribs 161. Preferably, prior to the implantation procedure, pushrod 300 and housing 100 are arranged in a locked position so that ribs 161 of housing 100 are positioned between distal stoppers 340 and proximal stoppers 350. Therefore, pushrod 300 is preferably maintained in place and is substantially prevented from sliding in or out of channel 150. Preferably, pushrod 300 can only be released from this locked position with sufficient force, thereby substantially reducing the risk of removing pushrod from the locked position unintentionally. Accordingly, the risk of unintentionally ejecting marker 20 and the risk of unintentionally losing sterility are substantially reduced as well.
When ejecting marker 20 from cannula 200, pushrod 300 can be lifted off proximal member 160 to avoid contact between proximal stoppers 350 and ribs 161, and preferably is pushed in direction X with sufficient force to overcome proximal stoppers 350, whereupon pushrod 300 can be pushed in direction X until tail 320 contacts stopping surface 132 which preferably prevents pushrod 300 from advancing any further in direction X. The distance from distal tip 210 of cannula 200 traveled by marker 20 can therefore be known and standardized, and substantially precise positioning of marker 20 within the animal can be facilitated.
An embodiment of a cover 30 is shown in
Cover 30 preferably comprises a cover bore 35 into which distal tip 210 of cannula 200 of implanter 10 can be inserted until a cover end surface 33 of a cover end 32 contacts a shoulder 133 of gripping structure 130, which preferably prevents further insertion of implanter 10 into cover 30. In accordance with a preferred embodiment of the invention, tubular member 110 of housing 100 comprises a distal end 120 having a rounded edge, thereby facilitating the insertion of tubular member 110 of housing 100 into cover 30. When cover end surface 33 engages shoulder 133, a cover rib 31 of cover 30 preferably engages a groove 121 of housing 100, thereby substantially maintaining cover 30 in position with respect to housing 100.
Preferably, cover rib 31 and groove 121 provide a barrier packaging between cover 30 and implanter 10 thereby maintaining the sterility of cannula 200 and the contents therein. Most preferably, as discussed above, rod 310 of pushrod 300 comprises a pushrod rib 360 which engages the inner surface of cannula bore 230. Accordingly, the area between cover rib 31 and pushrod rib 360 and its contents can preferably be sterilized with both cover 30 and rod 310 in place, and can maintain sterility until either cover 30 or pushrod 300 is removed. Preferably, cover 30 is removed immediately prior to implantation, thereby maintaining the sterility of cannula 200 and marker 20 until immediately prior to implantation. Whereas various methods and chemicals can be used to sterilize implanter 10, it is preferable to sterilize implanter 10 using ethylene oxide.
According to an embodiment of cover 30 shown in
In production, the individual pieces of the embodiment of implanter 10 shown in
In accordance with a preferred embodiment of the invention, the individually formed pieces of implanter 10 can be assembled in order to produce implanter 10. More specifically, cannula 200 can be inserted into bore 111 of tubular member 110 of housing 100 until proximal end 220 engages tubular shoulder 122. Preferably, housing 100 is molded with a plurality of ribs 123, more preferably about three ribs 123, on the inner surface of bore 111. Ribs 123 preferably assist in aligning cannula bore 230 with marker entrance 119. Once cannula 200 is in place, preferably while cannula is mechanically pushed against shoulder 122, an effective amount of an adhesive, preferably a UV curing bonding compound, is preferably inserted through adhesive aperture 115 into adhesive receiving space 114 of housing 100 in order to secure cannula 200 to housing 100. Preferably, the adhesive will substantially fill the area inside adhesive receiving space 114 and outside cannula 200, thereby sealing the gap between cannula 200 and housing 100 with the adhesive. Therefore, a substantially permanent bond is preferably created between housing 100 and cannula 200.
According to a preferred embodiment of the invention, an automated system is utilized to insert cannula 200 into housing 100, and preferably, the injection of the adhesive. Whereas the components can be manually assembled without deviating from the scope of the invention, an automated, such as a system robot and laser guide system, can substantially reduce the probability of error and misalignment and can reduce the potential risk of damaging the sharp distal tip 210 of cannula 200. A robotic system can also improve the efficiency in assembling the two components by preventing distal tip 210 of cannula 200 from contacting any object, thereby substantially reducing the risk of damaging distal tip 210 of cannula 200.
Marker 20 can be inserted into channel 150 and pushed by pushrod 300 into a desirable position within cannula 200. Implanter 10 having marker 20 inserted therein can thereafter be sterilized, preferably with ethylene oxide, most preferably with cover 30 and pushrod 300 in place. In accordance with an embodiment of the invention as shown in
According to an embodiment of the invention, cover 30 is injection molded and comprises polyethylene, and most preferably is substantially clear and provides visualization of cannula 200.
In use, if the assembly was sterilized, or after sterilizing the assembly at the laboratory wherein the implantation is performed, the user can remove cover 30 and insert implanter 10 into the animal being studied, preferably until distal end 120 of tubular member 110 of housing 100 contacts the skin of the animal. The user can thereafter push pushrod 300 in direction X by exerting a pushing force on tail 320 of pushrod 300, which will preferably eject marker 20 from within cannula 200 into the tissue of the animal. The spent implanter can be removed from the animal and is preferably discarded or sterilized for subsequent use. Most preferably, the spent implanter is discarded after a single use.
The examples provided are merely exemplary, as a matter of application specific to design choice, and should not be construed to limit the scope of the invention in any way.
Thus, while there have been shown and described and pointed out novel features of the present invention as applied to preferred embodiments thereof, it will be understood that various omissions and substitutions and changes in the form and details of the disclosed invention may be made by those skilled in the art without departing from the spirit of the invention. For example, housing 100 can exclude gripping surface 131, alter the number of stopping surfaces 132, including excluding it entirely, without deviating from the scope of the invention as a matter of application specific to design choice. Housing 100, pushrod 300, cannula 200 and/or cover 30 can comprise different materials than those described without deviating from the scope of the invention. The location, size, shape, and any other physical features of adhesive receiving space 114 can also be changed without deviating from the scope of the invention, as a matter of application specific to design choice. Additionally, other alterations, as a way of non-limiting example, marker entrance 119 can comprise substantially the same diameter of proximal portion 113 of bore 111, proximal portion 113 and distal portion 112 of bore 111 can comprise a diameter greater than or substantially equivalent to proximal ring 117 and distal ring 116, rod 310 of pushrod 300 can comprise different diameters, rod 310 can be non-cylindrical, tubular member 110 may be non-cylindrical, bore 111 can be non-cylindrical, etc., as a matter of application specific to design choice, without deviating from the scope of the invention. It is the intention, therefore, to be limited only as indicated by the scope of the claims appended hereto.
It is also to be understood that the following claims are intended to cover all of the generic and specific features of the invention herein described and all statements of the scope of the invention which, as a matter of language, might be said to fall therebetween.
This application claims the benefit of U.S. Provisional Application Ser. No. 60/699,115, filed on Jul. 13, 2005, entitled “IMPLANTER”, hereby incorporated by reference.
Number | Date | Country | |
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60699115 | Jul 2005 | US |