Claims
- 1. An isolated polypeptide comprising an amino acid sequence selected from the following:
- 2. An isolated polypeptide consisting of an amino acid sequence selected from the following:
- 3. A polypeptide comprising the peptide of claim 1 fused to a heterologous protein.
- 4. A polypeptide comprising the peptide of claim 2 fused to a heterologous protein.
- 5. The polypeptide of claim 3 wherein the heterologous protein is human serum albumin.
- 6. The polypeptide of claim 4 wherein the heterologous protein is human serum albumin.
- 7. A method of treating, preventing or ameliorating hypertension comprising administering to an animal in which such treatment, prevention, or amelioration is desired the polypeptide of claim 1, claim 2, claim 3, claim 4, claim 5, or claim 6 in an amount effective to treat, prevent, or ameliorate hypertension.
- 8. A method of treating, preventing or ameliorating congestive heart failure comprising administering to an animal in which such treatment, prevention, or amelioration is desired the polypeptide of claim 1, claim 2, claim 3, claim 4, claim 5, or claim 6 in an amount effective to treat, prevent, or ameliorate congestive heart failure.
- 9. A method of treating, preventing or ameliorating stroke comprising administering to an animal in which such treatment, prevention, or amelioration is desired the polypeptide of claim 1, claim 2, claim 3, claim 4, claim 5, or claim 6 in an amount effective to treat, prevent, or ameliorate stroke.
- 10. A method of treating, preventing or ameliorating left ventricular failure comprising administering to an animal in which such treatment, prevention, or amelioration is desired the polypeptide of claim 1, claim 2, claim 3, claim 4, claim 5, or claim 6 in an amount effective to treat, prevent, or ameliorate left ventricular failure.
- 11. A method of treating, preventing or ameliorating atherosclerotic heart disease comprising administering to an animal in which such treatment, prevention, or amelioration is desired the polypeptide of claim 1, claim 2, claim 3, claim 4, claim 5, or claim 6 in an amount effective to treat, prevent, or ameliorate atherosclerotic heart disease.
Parent Case Info
[0001] This application claims benefit under 35 U.S.C. §119(e) of U.S. Patent Application No. 60/294,976, filed Jun. 4, 2001, which is hereby incorporated by reference in its entirety.
Provisional Applications (1)
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Number |
Date |
Country |
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60294976 |
Jun 2001 |
US |