Claims
- 1. A method of preventing, inhibiting or reducing tumor cell growth comprising administering an effective amount of an agent that inhibits an OX-2 protein to a cell or an animal in need thereof.
- 2. A method according to claim 1 wherein the agent is a molecule that binds the OX-2 protein.
- 3. A method according to claim 2 wherein the agent is an antibody.
- 4. A method according to claim 1 wherein the agent is an antisense oligonucleotide that is complimentary to a nucleic acid sequence from an OX-2 gene.
- 5. A pharmaceutical composition for use in preventing, inhibiting or reducing tumor cell growth comprising an effective amount of an agent that inhibits OX-2 in admixture with a suitable diluent or carrier.
- 6. A composition according to claim 5 wherein the agent is a molecule that binds the OX-2 protein.
- 7. A composition according to claim 6 wherein the molecule is an antibody.
- 8. A composition according to claim 5 wherein the agent is an antisense oligonucleotide that is complimentary to a nucleic acid sequence from an OX-2 gene.
- 9. A method of inducing tumor cell growth or metastasis comprising administering an OX-2 protein or fragment thereof or a nucleic acid molecule encoding an OX-2 protein or fragment thereof to an animal in need thereof.
Parent Case Info
[0001] This application is a continuation-in-part of U.S. application Ser. No. 09/570,367 filed May 5, 1998 (now allowed) which is a continuation of PCT/CA98/01038 filed Nov. 6, 1998 (which designated the U.S.) which claims the benefit of U.S. Provisional application Ser. No. 60/064,764 filed Nov, 7, 1997 (now abandoned). This application also claims benefit of U.S. Provisional application Ser. No. 60/222,725 filed Aug. 3, 2000 (now pending). All of the prior applications are incorporated herein in their entirety.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60064764 |
Nov 1997 |
US |
|
60222725 |
Aug 2000 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
PCT/CA98/01038 |
Nov 1998 |
US |
Child |
09570367 |
May 2000 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09570367 |
May 2000 |
US |
Child |
09917278 |
Jul 2001 |
US |