Joyce, Pure & Appl. Chem 65 (1993), pp. 1205-1212. |
Mills, et al., "An Extracellular Darwinian Experiment With a Self-Duplicating Nucleic Acid Molecule", PNAS, USA 58: 217-224 (1967). |
Green, et al., "In Vitro Genetic Analysis of the Tetrahymena Self-Splicing Intron", Nature 347: 406-408 (1990). |
Chowrira, et al., "Novel Guanosine Requirement for Catalysis for the Hairpin Ribozyme", Nature 354: 320-322 (1991). |
Joyce, "Amplification, Mutation and Selection of Catalytic RNA", Gene 82: 83-87 (1989). |
Beaudry and Joyce, "Directed Evolution of an RNA Enzyme", Science 257: 635-641 (1992). |
Robertson and Joyce, "Selection In Vitro of an RNA Enzyme that Specifically Cleaves Single-Stranded DNA", Nature 344: 467-468 (1990). |
Tuerk, et al., "Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase", Science 249: 505-510 (1990). |
Ellington, et al., "In Vitro Selection of RNA Molecules that Bind Specific Ligands", Nature 346: 818-822 (1990). |
Lam, et al., "A New Type of Synthetic Peptide Library for Identifying Ligand-Binding Activity", Nature 354: 82-84 (1991). |
Scott, et al., "Searching for Peptide Ligands With an Epitope Library", Science 249: 386-390 (1990). |
Devlin, et al., "Random Peptide Libraries: A Source of Specific Protein Binding Molecules", Science 249: 404-406 (1990). |
Cwirla, et al., "Peptides on Phage: A Vast Library of Peptides for Identifying Ligands", PNAS USA 87: 6378-6382 (1990). |
Wang and Cech, "Tertiary Structure Around the Guanosine-Binding Site of the Tetrahymena Ribozyme", Science 256: 526-529 (1992). |
Zaug and Cech, "The Intervening Sequence RNA of Tetrahymena is an Enzyme", Science 231: 470-475 (1986). |
Inoue, et al., "New Reactions of the Ribosomal RNA Precursor of Tetrahymena and the Mechanism of Self-Splicing", J. Mol. Biol. 189: 143-165 (1986). |
Joyce, et al., "Catalytic Activity is Retained in the Tetrahymena Group I Intron Despite Removal of the Large Extension of Element P5", Nucl. Acids Res. 17: 7879-7889 (1989). |
Cadwell and Joyce, "Randomization of Genes by PCR Mutagenesis", PCR Methods Appl. 2: 28-33 (1992). |
Lehman & Joyce, "Evolution In Vitro of an RNA Enzyme With Altered Metal Dependence", Nature 361: 182-185 (1993). |
Joyce and Inoue, "A Novel Technique for the Rapid Preparation of Mutant RNAs", Nucl. Acids Res. 17: 711-722 (1989). |