Claims
- 1. An immunogenic composition comprising a vector that contains and expresses in vivo in a porcine host cell, a nucleic acid molecule or fragment thereof encoding a type II porcine circovirus antigen and a pharmaceutically acceptable vehicle or diluent.
- 2. The immunogenic composition of claim 1, wherein the vector is a viral vector.
- 3. The immunogenic composition of claim 1, wherein the vector is a plasmid.
- 4. The immunogenic composition of claim 1, wherein the composition induces an immunological response in a porcine host against type II porcine circovirus.
- 5. The immunogenic composition according to claim 1, further comprising an additional antigen of another porcine pathogen or a nucleic acid molecule that expresses the additional antigen of another porcine pathogen.
- 6. The immunogenic composition according to claim 5, wherein the additional antigen is from a porcine pathogen selected from the group consisting of porcine reproductive and respiratory syndrome (PRRS), Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, E. coli, porcine Atrophic Rhinitis, Aujeszky disease, Hog cholera and Swine Influenza.
- 7. The immunogenic composition according to claim 5, wherein the additional antigen is from PRRS.
- 8. The immunogenic composition according to claim 5, wherein the additional antigen is from PRRS and Mycoplasma hyopneumoniae.
- 9. The immunogenic composition according to claim 1, comprising an antigen of a first type II porcine circovirus strain, or a nucleic acid molecule that expresses the antigen, and an antigen of a second strain of type II porcine circovirus, or a nucleic acid molecule that expresses that antigen, wherein at least one of the first and second antigens is the vector that contains and expresses in vivo in a porcine host cell, a nucleic acid molecule or fragments thereof encoding a type II porcine circovirus antigen.
- 10. The immunogenic composition according to claim 9, wherein the first antigen is a porcine circovirus antigen selected from the group consisting of an inactivated porcine circovirus, a live attenuated porcine circovirus, and a sub-unit of a porcine circovirus, and the second antigen is the vector that contains and expresses in vivo in a porcine host cell, a nucleic acid molecule or fragment thereof encoding a type II porcine circovirus antigen.
- 11. The immunogenic composition according to claim 1, further comprising an adjuvant.
- 12. A method for inducing an immunological response against a porcine circovirus comprising administering to a porcine the immunogenic composition of any one of claims 1-11.
Priority Claims (3)
Number |
Date |
Country |
Kind |
97 12382 |
Oct 1997 |
FR |
|
98 00873 |
Jan 1998 |
FR |
|
98 03707 |
Mar 1998 |
FR |
|
RELATED APPLICATIONS
This application is a continuation-in-part of application Ser. No. 09/082,558, filed May 21, 1998, incorporated herein by reference. Reference is also made to French applications 97/12382, 98/00873 and 98/03707, filed respectively Oct. 10, 1997, Jan. 22, 1998, and Mar. 20, 1998, incorporated herein by reference; and this application claims priority from said French applications. In addition, all documents cited in the text of this application, and all references cited in documents cited in the text of this application, are hereby incorporated herein by reference.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
5795872 |
Ricigliano |
Aug 1998 |
A |
5888513 |
Plana Duran |
Mar 1999 |
A |
6217883 |
Allan et al. |
Apr 2001 |
B1 |
Foreign Referenced Citations (2)
Number |
Date |
Country |
2772047 |
Jun 1999 |
FR |
9929717 |
Jun 1999 |
WO |
Non-Patent Literature Citations (4)
Entry |
Hamel et al. Genbank Accession No.: 027217 Sep. 27, 1997.* |
Ellis et al. 1999. J. Vet. Diagn. Invest. 11: 3-14.* |
Ellis et al. 2000, J. Vet. Diagn. Invest.; 12(1): 21-27.* |
Ellis et al. Jan. 1998. Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome. Canadian Veterinary Journal. vol. 39 (1); 44-51. Abstract only. |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09/082558 |
May 1998 |
US |
Child |
09/161092 |
|
US |