Claims
- 1. A compound of the formula: ##STR525## or an acid addition salt thereof or an N-protected derivative thereof wherein at each occurrence the N-protecting group is independently selected from the group consisting of formyl, acetyl, pivaloyl, t-butylacetyl, t-butyloxycarbonyl, benzyloxycarbonyl, benzyl and isopropylaminocarbonyl.
- 2. A compound selected from the group consisting of:
- 2-(N-benzylamino)-5-(t-butyloxycarbonylamino)-3,4-dihydroxy-1,6-diphenylhexane;
- 2-(N-benzyl-N-(benzyloxycarbonyl)amino)-5-(t-butyloxycarbonylamino)-3,4-dihydroxy-1,6-diphenylhexane;
- 5-amino-2-(N-benzylamino)-3,4-dihydroxy-1,6-diphenylhexane;
- 2-amino-5-(t-butyloxycarbonylamino)-3,4-dihydroxy-1,6-diphenylhexane;
- 2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3R,4R,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3S,4S,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3R,4S,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3R,4R,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3S,4S,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3R,4S,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3S,4R,5S)-5-amino-2-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane; and
- (2S,3R,4S,5S)-2,5-di-(N-((isopropylaminocarbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- or an acid addition salt thereof.
- 3. A compound selected from the group consisting of:
- (2S,3R,4R,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3S,4S,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane; and
- (2S,3R,4S,5S)-2,5-di-(N-((t-butyloxy)carbonyl)amino)-3,4-dihydroxy-1,6-diphenylhexane.
- 4. A compound selected from the group consisting of:
- (2S,3R,4R,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane;
- (2S,3S,4S,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane; and
- (2S,3R,4S,5S)-2,5-diamino-3,4-dihydroxy-1,6-diphenylhexane;
- or an acid addition salt thereof.
Parent Case Info
This application is a division of U.S. patent application Ser. No. 08/358,648, filed Dec. 19, 1994, which is a continuation of U.S. patent application Ser. No. 08/164,979, filed Dec. 7, 1993, now abandoned, which is a continuation of U.S. patent application Ser. No. 07/880,729, filed May 8, 1992, now abandoned, which is a division of U.S. patent application Ser. No. 07/518,730, filed May 9, 1990, now U.S. Pat. No. 5,142,056, which is a is a continuation-in-part of U.S. patent application Ser. No. 456,124, filed Dec. 22, 1989, now abandoned, which is a continuation-in-part of U.S. patent application Ser. No. 405,604, filed Sep. 8, 1989, now abandoned, which is a continuation-in-part of U.S. patent application Ser. No. 355,945, filed May 23, 1989, now abandoned.
US Referenced Citations (2)
Number |
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2354866 |
Kempf et al. |
Oct 1994 |
|
5142056 |
Kempf et al. |
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|
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Divisions (2)
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Number |
Date |
Country |
Parent |
358648 |
Dec 1994 |
|
Parent |
518730 |
May 1990 |
|
Continuations (2)
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Number |
Date |
Country |
Parent |
164979 |
Dec 1993 |
|
Parent |
880729 |
May 1992 |
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Continuation in Parts (3)
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Number |
Date |
Country |
Parent |
456124 |
Dec 1989 |
|
Parent |
405604 |
Sep 1989 |
|
Parent |
355945 |
May 1989 |
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