Dihydrofolate reductase (1.5.1.3)

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CPC
C12Y105/01003

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12YENZYMES C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)

Current Industry

C12Y105/01003Dihydrofolate reductase (1.5.1.3)

Industries

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Patents Grantslast 30 patents

Information Patent Grant
DHFR tunable protein regulation
- Patent number 12,104,178
- Issue date Oct 1, 2024
- Obsidian Therapeutics, Inc.
- Vipin Suri
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Destabilising domains for conditionally stabilising a protein
- Patent number 12,049,650
- Issue date Jul 30, 2024
- BRAINGENE AB
- Mauno Vihinen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for selective protein degradation
- Patent number 11,999,802
- Issue date Jun 4, 2024
- Novartis AG
- James E. Bradner
- G01 - MEASURING TESTING
Information Patent Grant
Programmable protein circuits in living cells
- Patent number 11,965,191
- Issue date Apr 23, 2024
- California Institute of Technology
- Xiaojing Gao
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sensors, methods and kits for detecting NADPH based on resonance en...
- Patent number 11,959,121
- Issue date Apr 16, 2024
- Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
- Qiuliyang Yu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Vector including a translation-impaired dihydrofolate reductase gen...
- Patent number 11,781,146
- Issue date Oct 10, 2023
- National University Corporation Hokkaido University
- Yasuhiko Suzuki
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Protein enriched microvesicles and methods of making and using the...
- Patent number 11,643,635
- Issue date May 9, 2023
- Takara Bio USA, Inc.
- Michael Haugwitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
DHFR tunable protein regulation
- Patent number 11,629,340
- Issue date Apr 18, 2023
- Obsidian Therapeutics, Inc.
- Vipin Suri
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Ribosome-mediated incorporation of peptides and peptidomimetics
- Patent number 11,434,492
- Issue date Sep 6, 2022
- Arizona Board of Regents on behalf of Arizona State University
- Sidney Hecht
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Small molecules for dual function positron emission tomography (PET...
- Patent number 11,253,616
- Issue date Feb 22, 2022
- The Trustees of the University of Pennsylvania
- Michael Farwell
- G01 - MEASURING TESTING
Information Patent Grant
Regulation of gene expression by aptamer-mediated modulation of alt...
- Patent number 11,248,239
- Issue date Feb 15, 2022
- MEIRAGTX UK II LIMITED
- Alex R. Boyne
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chemically defined cell culture media additive
- Patent number 11,186,817
- Issue date Nov 30, 2021
- IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
- Hong-Woo Park
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Expression vector system comprising two selection markers
- Patent number 11,174,494
- Issue date Nov 16, 2021
- Novartis AG
- Thomas Jostock
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for preparing surfactant protein D (SP-D)
- Patent number 10,975,389
- Issue date Apr 13, 2021
- Airway Therapeutics, Inc.
- Jan Susan Rosenbaum
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Selection methods for genetically-modified T cells
- Patent number 10,808,230
- Issue date Oct 20, 2020
- Board of Regents, The University of Texas System
- David Rushworth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Protein enriched microvesicles and methods of making and using the...
- Patent number 10,793,828
- Issue date Oct 6, 2020
- Takara Bio USA, Inc.
- Michael Haugwitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods, compositions and cells for preparing surfactant protein D...
- Patent number 10,752,914
- Issue date Aug 25, 2020
- Airway Therapeutics, Inc.
- Jan Susan Rosenbaum
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Ribosome-mediated incorporation of peptides and peptidomimetics
- Patent number 10,745,705
- Issue date Aug 18, 2020
- ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
- Sidney Hecht
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Regulation of gene expression by aptamer-mediated modulation of alt...
- Patent number 10,494,646
- Issue date Dec 3, 2019
- MEIRAGTX UK II LIMITED
- Alex R. Boyne
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Combination therapy with an anti-hyaluronan agent and therapeutic a...
- Patent number 10,137,104
- Issue date Nov 27, 2018
- Halozyme, Inc.
- Daniel C. Maneval
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for improving recombinant protein expression
- Patent number 10,066,231
- Issue date Sep 4, 2018
- CMC ICOS BIOLOGICS, INC.
- Howard Robert Grahame Clarke
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Expression vector system comprising two selection markers
- Patent number 9,994,866
- Issue date Jun 12, 2018
- Novartis AG
- Thomas Jostock
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Combination therapy with an anti-hyaluronan agent and therapeutic a...
- Patent number 9,913,822
- Issue date Mar 13, 2018
- Halozyme, Inc.
- Daniel C. Maneval
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods and products for producing engineered mammalian cell lines...
- Patent number 9,822,381
- Issue date Nov 21, 2017
- Precision Biosciences, Inc.
- Derek Jantz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Expression vector
- Patent number 9,657,310
- Issue date May 23, 2017
- JCR PHARMACEUTICALS CO., LTD.
- Kenichi Takahashi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of making and using chemically self assembled-nanorings
- Patent number 9,499,800
- Issue date Nov 22, 2016
- Regents of The University of Minnesota
- Carston R. Wagner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Puro-DHFR quadrifunctional marker and its use in protein production
- Patent number 9,175,284
- Issue date Nov 3, 2015
- Merck Serono SA
- Michel Kobr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
PURO-DHFR quadrifunctional marker and its use in protein production
- Patent number 8,357,535
- Issue date Jan 22, 2013
- Merck Serono SA
- Michel Kobr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for identifying drug-sensitizing antisense DNA fragments and...
- Patent number 7,910,337
- Issue date Mar 22, 2011
- Trius Therapeutics, Inc.
- Robert Haselbeck
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Use of anti-sense sequences to increase responsiveness to gene ampl...
- Patent number 6,399,377
- Issue date Jun 4, 2002
- Yves Mory
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN
- Publication number 20250019672
- Publication date Jan 16, 2025
- BrainGene AB
- Mauno Vihinen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DHFR TUNABLE PROTEIN REGULATION
- Publication number 20240401004
- Publication date Dec 5, 2024
- Obsidian Therapeutics, Inc.
- Vipin SURI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
- Publication number 20240384007
- Publication date Nov 21, 2024
- Novartis AG
- James E. Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONTROL OF PROTEIN EXPRESSION WITH TMP-PROTAC COMPOUNDS
- Publication number 20240226100
- Publication date Jul 11, 2024
- The Trustees of the University of Pennsylvania
- Mark A. SELLMYER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION
- Publication number 20240101972
- Publication date Mar 28, 2024
- Spark Therapeutics, Inc.
- Mustafa Yazicioglu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS
- Publication number 20240011010
- Publication date Jan 11, 2024
- California Institute of Technology
- Zibo Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REAL-TIME CELLULAR THERMAL SHIFT ASSAY (RT-CETSA) FOR RESEARCH AND...
- Publication number 20230257756
- Publication date Aug 17, 2023
- The United States of America,as represented by the Secretary,Department of He...
- Mark J. Henderson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Protein Enriched Microvesicles and Methods of Making and Using the...
- Publication number 20230235278
- Publication date Jul 27, 2023
- Takara Bio USA, Inc.
- Michael Haugwitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TANDEM CD19 CAR-BASED COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
- Publication number 20230092895
- Publication date Mar 23, 2023
- Obsidian Therapeutics, Inc.
- Vipin Suri
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF TRANSCRIPTION
- Publication number 20230056856
- Publication date Feb 23, 2023
- Obsidian Therapeutics, Inc.
- Vipin Suri
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Ribosome-Mediated Incorporation of Peptides and Peptidomimetics
- Publication number 20230046194
- Publication date Feb 16, 2023
- Arizona Board of Regents on behalf of Arizona State University
- Sidney HECHT
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES...
- Publication number 20220333137
- Publication date Oct 20, 2022
- PRECISION BIOSCIENCES, INC.
- Derek JANTZ
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALT...
- Publication number 20220282278
- Publication date Sep 8, 2022
- MEIRAGTX UK II LIMITED
- Alex R. Boyne
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DHFR TUNABLE PROTEIN REGULATION
- Publication number 20220213449
- Publication date Jul 7, 2022
- Obsidian Therapeutics, Inc.
- Vipin SURI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD40L COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
- Publication number 20220175781
- Publication date Jun 9, 2022
- Obsidian Therapeutics, Inc.
- Michael SCHEBESTA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN
- Publication number 20220169993
- Publication date Jun 2, 2022
- BrainGene AB
- Mauno Vihinen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Small Molecules for Dual Function Positron Emission Tomography (PET...
- Publication number 20220133917
- Publication date May 5, 2022
- The Trustees of the University of Pennsylvania
- Michael Farwell
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYSTEMS AND METHODS FOR METABOLIC ENGINEERING
- Publication number 20220112470
- Publication date Apr 14, 2022
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Virginia W. CORNISH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
- Publication number 20220042036
- Publication date Feb 10, 2022
- Airway Therapeutics, Inc.
- Jan Susan Rosenbaum
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS TO ENRICH GENETICALLY ENGINEERED T CELLS
- Publication number 20220041999
- Publication date Feb 10, 2022
- NEOGENE THERAPEUTICS B.V.
- Carsten Linnemann
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DOUBLE KNOCK-OUT CHO CELL LINE METHOD OF ITS GENERATION AND PRODUCI...
- Publication number 20210317435
- Publication date Oct 14, 2021
- ENZENE BIOSCIENCES LIMITED
- Himanshu Gadgil
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Complement Component 1s (C1s) Deficient Cells for Production of Vac...
- Publication number 20210317168
- Publication date Oct 14, 2021
- The Regents of the University of California
- Sophia Li
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL VECTOR AND USE THEREOF
- Publication number 20210254079
- Publication date Aug 19, 2021
- National University Corporation Hokkaido University
- Yasuhiko SUZUKI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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PROGRAMMABLE PROTEIN CIRCUITS IN LIVING CELLS
- Publication number 20210238570
- Publication date Aug 5, 2021
- California Institute of Technology
- Xiaojing Gao
- C07 - ORGANIC CHEMISTRY
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CRISPR HAVING OR ASSOCIATED WITH DESTABILIZATION DOMAINS
- Publication number 20210139872
- Publication date May 13, 2021
- THE BROAD INSTITUTE, INC.
- Feng ZHANG
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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COMPOSITIONS AND METHODS FOR CHIMERIC LIGAND RECEPTOR (CLR)-MEDIATE...
- Publication number 20210130845
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- Poseida Therapeutics, Inc.
- Eric M. OSTERTAG
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SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS
- Publication number 20210054346
- Publication date Feb 25, 2021
- Board of Regents, The University of Texas System
- David RUSHWORTH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D...
- Publication number 20200407747
- Publication date Dec 31, 2020
- Airway Therapeutics, Inc.
- Jan Susan Rosenbaum
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Protein Enriched Microvesicles and Methods of Making and Using the...
- Publication number 20200377852
- Publication date Dec 3, 2020
- Takara Bio USA, Inc.
- Michael Haugwitz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Ribosome-Mediated Incorporation of Peptides and Peptidomimetics
- Publication number 20200370057
- Publication date Nov 26, 2020
- Arizona Board of Regents on behalf of Arizona State University
- Sidney HECHT
- C07 - ORGANIC CHEMISTRY

Dihydrofolate reductase (1.5.1.3)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

DHFR tunable protein regulation

Destabilising domains for conditionally stabilising a protein

Compositions and methods for selective protein degradation

Programmable protein circuits in living cells

Sensors, methods and kits for detecting NADPH based on resonance en...

Vector including a translation-impaired dihydrofolate reductase gen...

Protein enriched microvesicles and methods of making and using the...

DHFR tunable protein regulation

Ribosome-mediated incorporation of peptides and peptidomimetics

Small molecules for dual function positron emission tomography (PET...

Regulation of gene expression by aptamer-mediated modulation of alt...

Chemically defined cell culture media additive

Expression vector system comprising two selection markers

Methods and compositions for preparing surfactant protein D (SP-D)

Selection methods for genetically-modified T cells

Protein enriched microvesicles and methods of making and using the...

Methods, compositions and cells for preparing surfactant protein D...

Ribosome-mediated incorporation of peptides and peptidomimetics

Regulation of gene expression by aptamer-mediated modulation of alt...

Combination therapy with an anti-hyaluronan agent and therapeutic a...

Methods for improving recombinant protein expression

Expression vector system comprising two selection markers

Combination therapy with an anti-hyaluronan agent and therapeutic a...

Methods and products for producing engineered mammalian cell lines...

Expression vector

Methods of making and using chemically self assembled-nanorings

Puro-DHFR quadrifunctional marker and its use in protein production

PURO-DHFR quadrifunctional marker and its use in protein production

Method for identifying drug-sensitizing antisense DNA fragments and...

Use of anti-sense sequences to increase responsiveness to gene ampl...

Patents Applicationslast 30 patents

DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN

DHFR TUNABLE PROTEIN REGULATION

COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION

CONTROL OF PROTEIN EXPRESSION WITH TMP-PROTAC COMPOUNDS

METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION

SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS

REAL-TIME CELLULAR THERMAL SHIFT ASSAY (RT-CETSA) FOR RESEARCH AND...

Protein Enriched Microvesicles and Methods of Making and Using the...

TANDEM CD19 CAR-BASED COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY

COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OF TRANSCRIPTION

Ribosome-Mediated Incorporation of Peptides and Peptidomimetics

METHODS AND PRODUCTS FOR PRODUCING ENGINEERED MAMMALIAN CELL LINES...

REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALT...

DHFR TUNABLE PROTEIN REGULATION

CD40L COMPOSITIONS AND METHODS FOR TUNABLE REGULATION

DESTABILISING DOMAINS FOR CONDITIONALLY STABILISING A PROTEIN

Small Molecules for Dual Function Positron Emission Tomography (PET...

SYSTEMS AND METHODS FOR METABOLIC ENGINEERING

METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)

METHODS TO ENRICH GENETICALLY ENGINEERED T CELLS

DOUBLE KNOCK-OUT CHO CELL LINE METHOD OF ITS GENERATION AND PRODUCI...

Complement Component 1s (C1s) Deficient Cells for Production of Vac...

NOVEL VECTOR AND USE THEREOF

PROGRAMMABLE PROTEIN CIRCUITS IN LIVING CELLS

CRISPR HAVING OR ASSOCIATED WITH DESTABILIZATION DOMAINS

COMPOSITIONS AND METHODS FOR CHIMERIC LIGAND RECEPTOR (CLR)-MEDIATE...

SELECTION METHODS FOR GENETICALLY-MODIFIED T CELLS

METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D...

Protein Enriched Microvesicles and Methods of Making and Using the...

Ribosome-Mediated Incorporation of Peptides and Peptidomimetics