DNA ligase (ATP) (6.5.1.1)

Industry

CPC
C12Y605/01001

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12YENZYMES C12Y605/00Ligases forming phosphoric ester bonds (6.5)

Current Industry

C12Y605/01001DNA ligase (ATP) (6.5.1.1)

Industries

Patents Grantslast 30 patents

Information Patent Grant
Method for generating higher order genome editing libraries
- Patent number 12,091,656
- Issue date Sep 17, 2024
- Johann Wolfgang Goethe-Universität Frankfur
- Manuel Kaulich
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for identifying a location of an RNA in a biological sample
- Patent number 11,952,627
- Issue date Apr 9, 2024
- 10X GENOMICS, INC.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Increasing capture efficiency of spatial assays
- Patent number 11,898,205
- Issue date Feb 13, 2024
- 10X GENOMICS, INC.
- Felice Alessio Bava
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 11,834,711
- Issue date Dec 5, 2023
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T4 DNA ligase variants with increased thermostability
- Patent number 11,788,082
- Issue date Oct 17, 2023
- AbClonal Science, Inc.
- Zhenyu Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for identifying a location of an RNA in a biological sample
- Patent number 11,761,038
- Issue date Sep 19, 2023
- 10X GENOMICS, INC.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for attaching one or more polynucleotide binding proteins to...
- Patent number 11,725,235
- Issue date Aug 15, 2023
- Oxford Nanopore Technologies PLC
- Andrew John Heron
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T4 DNA ligase variants with increased resistance to salt
- Patent number 11,685,913
- Issue date Jun 27, 2023
- AbClonal Science, Inc.
- Alicia DiCicco
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Enzymatic ligation of nucleic acids
- Patent number 11,661,629
- Issue date May 30, 2023
- Life Technologies Corporation
- Stephen Hendricks
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
In vitro recombination method
- Patent number 11,542,529
- Issue date Jan 3, 2023
- Codex DNA, Inc.
- Lei Young
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Enhanced adaptor ligation
- Patent number 11,279,972
- Issue date Mar 22, 2022
- Swift Biosciences, Inc.
- Vladimir Makarov
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 11,180,800
- Issue date Nov 23, 2021
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multiple ligase compositions, systems, and methods
- Patent number 11,124,789
- Issue date Sep 21, 2021
- RGENE, INC.
- Yu Zheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method to alter Chinese hamster ovary cell line stability
- Patent number 11,124,772
- Issue date Sep 21, 2021
- University of Delaware
- Kelvin Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method of preparing cell free nucleic acid molecules by in situ amp...
- Patent number 11,015,213
- Issue date May 25, 2021
- CIRCULOGENE THERANOSTICS, LLC
- Chen-Hsiung Yeh
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Double-strand DNA break quantification method
- Patent number 10,907,199
- Issue date Feb 2, 2021
- Marie-Chantal Gregoire
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
DNA ligase variants
- Patent number 10,837,009
- Issue date Nov 17, 2020
- New England Biolabs, Inc.
- Jennifer Ong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Molecular detection using ligation amplification
- Patent number 10,781,477
- Issue date Sep 22, 2020
- ARATOME, LLC
- Jay Trautman
- G01 - MEASURING TESTING
Information Patent Grant
Method for establishing eukaryotic expression cell line of CD36 mut...
- Patent number 10,711,046
- Issue date Jul 14, 2020
- NAN-NING INSTITUTE OF TRANSFUSION MEDICINE
- Guoguang Wu
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sample preparation methods, systems and compositions
- Patent number 10,697,008
- Issue date Jun 30, 2020
- KARIUS, INC.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Construction of next generation sequencing (NGS) libraries using co...
- Patent number 10,683,542
- Issue date Jun 16, 2020
- Integrated DNA Technologies, Inc.
- Zachary Zwirko
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Processes for the production of oligonucleotides
- Patent number 10,640,812
- Issue date May 5, 2020
- GlaxoSmithKline Intellectual Property Development Limited
- Andreas Crameri
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Low sequence bias single-stranded DNA ligation
- Patent number 10,640,828
- Issue date May 5, 2020
- The Penn State Research Foundation
- Philip C. Bevilacqua
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multiple ligase compositions, systems, and methods
- Patent number 10,626,390
- Issue date Apr 21, 2020
- RGENE, INC.
- Yu Zheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
In vitro recombination method
- Patent number 10,577,629
- Issue date Mar 3, 2020
- SGI-DNA, Inc.
- Lei Young
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified nucleotides methods and kits
- Patent number 10,526,652
- Issue date Jan 7, 2020
- Pierce Biotechnology, Inc.
- Christopher L. Etienne
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Enzymatic ligation of nucleic acids
- Patent number 10,494,671
- Issue date Dec 3, 2019
- Life Technologies Corporation
- Stephen Hendricks
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Universal enzyme responsive linker for assembling ligands on DNA fu...
- Patent number 10,392,411
- Issue date Aug 27, 2019
- University of Connecticut
- Jessica Lynn Rouge
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Method for attaching one or more polynucleotide binding proteins to...
- Patent number 10,385,389
- Issue date Aug 20, 2019
- Oxford Nanopore Technologies Ltd.
- Andrew John Heron
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Universal enzyme responsive linker for assembling ligands on DNA fu...
- Patent number 10,208,072
- Issue date Feb 19, 2019
- University of Conneticut
- Jessica Lynn Rouge
- B82 - NANO-TECHNOLOGY

Patents Applicationslast 30 patents

Information Patent Application
METHOD FOR GENERATING HIGHER ORDER GENOME EDITING LIBRARIES
- Publication number 20250043271
- Publication date Feb 6, 2025
- JOHANN WOLFGANG GOETHE-UNIVERSITAT FRANKFURT AM MAIN
- Manuel KAULICH
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
T7 DNA Ligase Variants R129D with Increased Specificity for Cohesiv...
- Publication number 20240392336
- Publication date Nov 28, 2024
- AbClonal Science, Inc.
- Dapeng Sun
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID
- Publication number 20240352443
- Publication date Oct 24, 2024
- DNA Script
- Sandrine CRETON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED DNA LIGASE VARIANTS
- Publication number 20240309353
- Publication date Sep 19, 2024
- Codexis, Inc.
- Jacob Hansen Artz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
- Publication number 20240301488
- Publication date Sep 12, 2024
- 10X Genomics, Inc.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
- Publication number 20240294979
- Publication date Sep 5, 2024
- Karius, Inc.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T7 DNA Ligase Variants Having Increased Ligation Efficiency
- Publication number 20240247246
- Publication date Jul 25, 2024
- AbClonal Science, Inc.
- Dapeng Sun
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE-FREE ENZYMATIC SYNTHES...
- Publication number 20240209407
- Publication date Jun 27, 2024
- CAMENA BIOSCIENCE LIMITED
- Derek STEMPLE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID PROCESSING VIA CIRCULARIZATION
- Publication number 20240209346
- Publication date Jun 27, 2024
- 10X Genomics, Inc.
- Shankar Shastry
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS
- Publication number 20240182968
- Publication date Jun 6, 2024
- 10X Genomics, Inc.
- Felice Alessio Bava
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Methods of Library Preparation
- Publication number 20240175010
- Publication date May 30, 2024
- Illumina, Inc.
- Allison Yunghans
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T4 DNA Ligase Variants with Increased Resistance to Salt
- Publication number 20240067951
- Publication date Feb 29, 2024
- AbClonal Science, Inc.
- Alicia DiCicco
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO...
- Publication number 20240026441
- Publication date Jan 25, 2024
- Oxford Nanopre Technologies PLC
- Andrew John Heron
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HIGH-SPEED PHOTO-CROSS-LINKING LINKER FOR MOLECULAR INTERACTION ANA...
- Publication number 20240002838
- Publication date Jan 4, 2024
- Saitama University
- Naoto Nemoto
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE
- Publication number 20230383344
- Publication date Nov 30, 2023
- 10X Genomics, Inc.
- Marlon Stoeckius
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR DISPLAYING BISPECIFIC ANTIBODY ON SURFACE OF MAMMALIAN C...
- Publication number 20230331871
- Publication date Oct 19, 2023
- DDBIO. CO, LTD., (SHANG HAI)
- Chen ZHOU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T4 DNA Ligase Variants with Increased Thermostability
- Publication number 20230265412
- Publication date Aug 24, 2023
- AbClonal Science, Inc.
- Zhenyu Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ATP-DEPENDENT DNA LIGASE
- Publication number 20230125232
- Publication date Apr 27, 2023
- ArcticZymes AS
- Bernd Ketelsen Striberny
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PREPARATION METHOD FOR DNA NEXT-GENERATION SEQUENCING LIBRARY
- Publication number 20230067708
- Publication date Mar 2, 2023
- DAAN GENE CO., LTD.
- ZHIKUN LIANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Nucleobase Editors
- Publication number 20230051661
- Publication date Feb 16, 2023
- Agency for Science, Technology and Research
- Liwei Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
- Publication number 20220186304
- Publication date Jun 16, 2022
- Karius, Inc.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF...
- Publication number 20220162687
- Publication date May 26, 2022
- The Regents of the University of Colorado, a Body Corporate
- Brian DEDECKER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Enhanced Adaptor Ligation
- Publication number 20220162688
- Publication date May 26, 2022
- SWIFT BIOSCIENCES, INC.
- VLADIMIR MAKAROV
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR PRODUCING MODIFIED OLIGONUCLEOTIDE COMPRISING COMPLEMENT...
- Publication number 20220041645
- Publication date Feb 10, 2022
- AJINOMOTO CO., INC.
- Daisuke TAKAHASHI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD TO ALTER CHINESE HAMSTER OVARY CELL LINE STABILITY
- Publication number 20210380948
- Publication date Dec 9, 2021
- University of Delaware
- Kelvin LEE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS
- Publication number 20210238680
- Publication date Aug 5, 2021
- 10X Genomics, Inc.
- Felice Alessio Bava
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS
- Publication number 20200399691
- Publication date Dec 24, 2020
- Karius, Inc.
- Timothy A. Blauwkamp
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES
- Publication number 20200277659
- Publication date Sep 3, 2020
- GlaxoSmithKline Intellectual Property Development Limited
- Andreas CRAMERI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MULTIPLE LIGASE COMPOSITIONS, SYSTEMS, AND METHODS
- Publication number 20200248166
- Publication date Aug 6, 2020
- RGENE, Inc.
- Yu Zheng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IN VITRO RECOMBINATION METHOD
- Publication number 20200190539
- Publication date Jun 18, 2020
- SGI-DNA, INC.
- Lei Young
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

DNA ligase (ATP) (6.5.1.1)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Method for generating higher order genome editing libraries

Methods for identifying a location of an RNA in a biological sample

Increasing capture efficiency of spatial assays

Sample preparation methods, systems and compositions

T4 DNA ligase variants with increased thermostability

Methods for identifying a location of an RNA in a biological sample

Method for attaching one or more polynucleotide binding proteins to...

T4 DNA ligase variants with increased resistance to salt

Enzymatic ligation of nucleic acids

In vitro recombination method

Enhanced adaptor ligation

Sample preparation methods, systems and compositions

Multiple ligase compositions, systems, and methods

Method to alter Chinese hamster ovary cell line stability

Method of preparing cell free nucleic acid molecules by in situ amp...

Double-strand DNA break quantification method

DNA ligase variants

Molecular detection using ligation amplification

Method for establishing eukaryotic expression cell line of CD36 mut...

Sample preparation methods, systems and compositions

Construction of next generation sequencing (NGS) libraries using co...

Processes for the production of oligonucleotides

Low sequence bias single-stranded DNA ligation

Multiple ligase compositions, systems, and methods

In vitro recombination method

Modified nucleotides methods and kits

Enzymatic ligation of nucleic acids

Universal enzyme responsive linker for assembling ligands on DNA fu...

Method for attaching one or more polynucleotide binding proteins to...

Universal enzyme responsive linker for assembling ligands on DNA fu...

Patents Applicationslast 30 patents

METHOD FOR GENERATING HIGHER ORDER GENOME EDITING LIBRARIES

T7 DNA Ligase Variants R129D with Increased Specificity for Cohesiv...

METHOD FOR GENERATING DOUBLE-STRANDED NUCLEIC ACID

ENGINEERED DNA LIGASE VARIANTS

METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE

SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS

T7 DNA Ligase Variants Having Increased Ligation Efficiency

COMPOSITIONS AND METHODS FOR PHOSPHORAMIDITE-FREE ENZYMATIC SYNTHES...

NUCLEIC ACID PROCESSING VIA CIRCULARIZATION

INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS

Methods of Library Preparation

T4 DNA Ligase Variants with Increased Resistance to Salt

METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO...

HIGH-SPEED PHOTO-CROSS-LINKING LINKER FOR MOLECULAR INTERACTION ANA...

METHODS FOR IDENTIFYING A LOCATION OF AN RNA IN A BIOLOGICAL SAMPLE

METHOD FOR DISPLAYING BISPECIFIC ANTIBODY ON SURFACE OF MAMMALIAN C...

T4 DNA Ligase Variants with Increased Thermostability

ATP-DEPENDENT DNA LIGASE

PREPARATION METHOD FOR DNA NEXT-GENERATION SEQUENCING LIBRARY

Nucleobase Editors

SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS

NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF...

Enhanced Adaptor Ligation

METHOD FOR PRODUCING MODIFIED OLIGONUCLEOTIDE COMPRISING COMPLEMENT...

METHOD TO ALTER CHINESE HAMSTER OVARY CELL LINE STABILITY

INCREASING CAPTURE EFFICIENCY OF SPATIAL ASSAYS

SAMPLE PREPARATION METHODS, SYSTEMS AND COMPOSITIONS

NOVEL PROCESSES FOR THE PRODUCTION OF OLIGONUCLEOTIDES

MULTIPLE LIGASE COMPOSITIONS, SYSTEMS, AND METHODS

IN VITRO RECOMBINATION METHOD