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C12N15/907
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C12
Biochemistry
C12N
MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
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C12N15/907
in mammalian cells
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Patents Grants
last 30 patents
Information
Patent Grant
CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
12,365,887
Issue date
Jul 22, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Universal donor cells
Patent number
12,365,915
Issue date
Jul 22, 2025
CRISPR THERAPEUTICS AG
Alireza Rezania
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for producing genome-edited cell
Patent number
12,365,923
Issue date
Jul 22, 2025
Osaka University
Shinichiro Nakada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modifying a target nucleic acid
Patent number
12,359,179
Issue date
Jul 15, 2025
The Regents of the University of California
Alexander Marson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DNA plasmids for the fast generation of homologous recombination ve...
Patent number
12,359,222
Issue date
Jul 15, 2025
Temple University - of the Commonwealth System of Higher Education
Oscar M. Perez-Leal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Systems and methods for modulating chromosomal rearrangements
Patent number
12,359,223
Issue date
Jul 15, 2025
Editas Medicine, Inc.
Cecilia Cotta-Ramusino
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene-modifying endonucleases
Patent number
12,351,818
Issue date
Jul 8, 2025
Amber Bio Inc.
Basem Al-Shayeb
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Rationally-designed single-chain meganucleases with non-palindromic...
Patent number
12,351,839
Issue date
Jul 8, 2025
Precision Biosciences, Inc.
James Jefferson Smith
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CPF1 complexes with reduced indel activity
Patent number
12,344,838
Issue date
Jul 1, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Drug-resistant immune cells and methods of use thereof
Patent number
12,343,397
Issue date
Jul 1, 2025
Regents of The University of Minnesota
Mark J. Osborn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene-edited natural killer cells
Patent number
12,344,655
Issue date
Jul 1, 2025
CRISPR THERAPEUTICS AG
Valentin Sluch
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Systems for cell control
Patent number
12,344,855
Issue date
Jul 1, 2025
CELLINO BIOTECH, INC.
Stan Wang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleobase editors and uses thereof
Patent number
12,344,869
Issue date
Jul 1, 2025
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-guided nucleases and active fragments and variants thereof and...
Patent number
12,338,455
Issue date
Jun 24, 2025
Life Edit Therapeutics, Inc.
Alexandra Briner Crawley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Crispr-CPF1-related methods, compositions and components for cancer...
Patent number
12,325,854
Issue date
Jun 10, 2025
Editas Medicine, Inc.
Gordon Grant Welstead
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for increasing efficiency of gene editing in cells
Patent number
12,325,865
Issue date
Jun 10, 2025
President and Fellows of Harvard College
George M. Church
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for targeting, editing, or modifying genes
Patent number
12,319,932
Issue date
Jun 3, 2025
Celyntra Therapeutics SA
Andrea Barghetti
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Unconstrained genome targeting with near-PAMless engineered CRISPR-...
Patent number
12,312,613
Issue date
May 27, 2025
The General Hospital Corporation
Benjamin Kleinstiver
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid-encapsulated dual-cleaving endonuclease for DNA and gene editing
Patent number
12,312,615
Issue date
May 27, 2025
Specific Biologics Inc.
David R. Edgell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR-Cas effector polypeptides and methods of use thereof
Patent number
12,312,616
Issue date
May 27, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Suppression of cytokine release syndrome in chimeric antigen recept...
Patent number
12,304,941
Issue date
May 20, 2025
Washington University
John DiPersio
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
pAPN mutant and composition for site-directed modification of pAPN...
Patent number
12,297,468
Issue date
May 13, 2025
AGSINO GENSOURCES CO., LTD.
Kui Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Non-human animals expressing exogenous terminal deoxynucleotidyltra...
Patent number
12,295,354
Issue date
May 13, 2025
REGENERON PHARMACEUTICALS, INC.
Lynn Macdonald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR-Cas13 system and use thereof
Patent number
12,297,450
Issue date
May 13, 2025
GUANGZHOU REFORGENE MEDICINE CO., LTD.
Junbin Liang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method of cell therapy
Patent number
12,297,274
Issue date
May 13, 2025
Jürgen Herbert Ernst Kuball
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid-encapsulated dual-cleaving endonuclease for DNA and gene editing
Patent number
12,297,467
Issue date
May 13, 2025
SPECIFIC BIOLOGICS INC.
David R. Edgell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered CAS9 systems for eukaryotic genome modification
Patent number
12,297,449
Issue date
May 13, 2025
Sigma-Aldrich Co. LLC
Timothy Seebeck
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for screening variant of target gene
Patent number
12,291,706
Issue date
May 6, 2025
APPLIED STEMCELL, INC.
Alfonso Farruggio
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genome editing methods and constructs
Patent number
12,285,495
Issue date
Apr 29, 2025
FONDAZIONE TELETHON ETS
Alberto Auricchio
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and kits for identifying cancer treatment targets
Patent number
12,286,623
Issue date
Apr 29, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
GENE EDITING REPORTER SYSTEM AND GUIDE RNA AND COMPOSITION RELATED...
Publication number
20250235559
Publication date
Jul 24, 2025
Incisive Genetics Inc.
Blair LEAVITT
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NON-LTR RETROTRANSPOSON SYSTEM AND USE THEREOF
Publication number
20250236890
Publication date
Jul 24, 2025
Beijing AstraGenomics Technology Co., Ltd.
Chen ZHAO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR INTRATUMORAL DELIVERY OF CRISPR/CAS SYSTEMS
Publication number
20250235555
Publication date
Jul 24, 2025
Christiana Care Gene Editing Institute, Inc.
Eric B. Kmiec
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CRISPR/CAS9-BASED FUSION PROTEINS FOR MODULATING GENE EXPRESSION AN...
Publication number
20250236854
Publication date
Jul 24, 2025
Glaxosmithkline Intellectual Property Development Limited GSK Medicines Rese...
Syandan Chakraborty
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED CHIMERIC ISCB POLYPEPTIDES AND USES THEREOF
Publication number
20250236857
Publication date
Jul 24, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Inhibition of NHEJ, MMEJ, and 53BP1 Promotes High Levels of HDR
Publication number
20250236892
Publication date
Jul 24, 2025
Integrated DNA Technologies, Inc.
Steve Ehren GLENN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MATERIALS AND METHODS FOR TREATMENT OF HEREDITARY HAEMOCHROMATOSIS
Publication number
20250235561
Publication date
Jul 24, 2025
CRISPR Therapeutics AG
Roman Lvovitch Bogorad
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENETICALLY MODIFIED NON-HUMAN MAMMALS, PREPARATION METHODS THEREFO...
Publication number
20250234846
Publication date
Jul 24, 2025
RENGENE BIOTECHNOLOGY CO., LTD.
Haoyi WANG
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYM...
Publication number
20250236856
Publication date
Jul 24, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OPTIMIZED RETRON EDITORS FOR EFFICIENT GENOME ENGINEERING AND DELIV...
Publication number
20250236891
Publication date
Jul 24, 2025
NEW YORK UNIVERSITY
John Poirier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR TARGETED GENE INSERTION INTO IMMUNE CELLS
Publication number
20250235477
Publication date
Jul 24, 2025
Miltenyi Biotec B.V. & Co. KG
Dominik LOCK
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE THERAPY FOR AUTOSOMAL DOMINANT DISEASES
Publication number
20250235556
Publication date
Jul 24, 2025
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Wen-Hsuan WU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE EDITING METHODS FOR TREATING ALPHA-1 ANTITRYPSIN (AAT) DEFICIENCY
Publication number
20250228973
Publication date
Jul 17, 2025
PRECISION BIOSCIENCES, INC.
James Jefferson Smith
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SAFETY SWITCHES TO CONTROL IN VITRO AND IN VIVO PROLIFERATION OF CE...
Publication number
20250230470
Publication date
Jul 17, 2025
Sana Biotechnology, Inc.
Eleonore THAM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENOME INSERTIONS IN CELLS
Publication number
20250230471
Publication date
Jul 17, 2025
Addition Therapeutics, Inc.
Reema ALDAIMALANI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
Publication number
20250230424
Publication date
Jul 17, 2025
Caribou Biosciences, Inc.
Stan Johan Josef Brouns
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELLS HAVING SOLID TUMOR TARGETING BACKBONE AND USE THEREOF
Publication number
20250228943
Publication date
Jul 17, 2025
FATE THERAPEUTICS, INC.
Bahram VALAMEHR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR TREATING LIPOPROTEIN-RELATED DISEASES
Publication number
20250228975
Publication date
Jul 17, 2025
CRISPR Therapeutics AG
Sanjay D'SOUZA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HYBRID CRISPR-CAS SYSTEMS AND METHODS OF USE THEREOF
Publication number
20250223577
Publication date
Jul 10, 2025
THE BROAD INSTITUTE, INC.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENOME EDITING METHODS AND CONSTRUCTS
Publication number
20250222140
Publication date
Jul 10, 2025
Fondazione Telethon ETS
Alberto Auricchio
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED CASCADE RIBONUCLEOPROTEINS AND USES THEREOF
Publication number
20250223578
Publication date
Jul 10, 2025
Caribou Biosciences, Inc.
Stan Johan Josef Brouns
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENE EDITING SYSTEM FOR TREATING USHER SYNDROME
Publication number
20250222136
Publication date
Jul 10, 2025
GenKOre, Inc.
Yong Sam KIM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TARGET SYSTEM FOR HOMOLOGY-DIRECTED REPAIR AND GENE EDITING METHOD...
Publication number
20250215457
Publication date
Jul 3, 2025
GENKORE INC
Yong Sam KIM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Production of reverse transcribed DNA (RT-DNA) using a retron rever...
Publication number
20250215458
Publication date
Jul 3, 2025
The Regents of the University of California
Seth Shipman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR PREDICTING OFF-TARGET WHICH CAN OCCUR IN PROCESS OF EDIT...
Publication number
20250215488
Publication date
Jul 3, 2025
Toolgen Incorporated
Jeongjoon LEE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS INCLUDING IFNE AND USES THEREOF
Publication number
20250213721
Publication date
Jul 3, 2025
Memorial Sloan-Kettering Cancer Center
Francisco M. Barriga
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR ENGINEERING TREG CELLS FOR TREATMENT O...
Publication number
20250213686
Publication date
Jul 3, 2025
Seattle Children's Hospital (dba Seattle Children's Research Institute)
Jane Buckner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NEXT GENERATION DESIGNER LIVER ORGANOIDS AND THEIR METHODS OF PREPA...
Publication number
20250207101
Publication date
Jun 26, 2025
Arizona Board of Regents on behalf of Arizona State University
Samira Kiani
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CASZ COMPOSITIONS AND METHODS OF USE
Publication number
20250207152
Publication date
Jun 26, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INTEGRATION OF LARGE NUCLEIC ACIDS INTO GENOMES
Publication number
20250207153
Publication date
Jun 26, 2025
The Regents of the University of California
Patrick Hsu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...