in mammalian cells

Industry

CPC
C12N15/907

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Parent Industries

CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N15/00Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors

Current Industry

C12N15/907in mammalian cells

Industries

Patents Grantslast 30 patents

Information Patent Grant
Engineered class 2 type V CRISPR systems
- Patent number 12,163,125
- Issue date Dec 10, 2024
- Scribe Therapeutics Inc.
- Gayathri Vijayakumar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Non-human animals having a humanized signal-regulatory protein gene
- Patent number 12,161,097
- Issue date Dec 10, 2024
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Type II CRISPR/Cas9 genome editing system and the application thereof
- Patent number 12,157,886
- Issue date Dec 3, 2024
- ZHUHAI SHU TONG MEDICAL TECHNOLOGY CO., LTD.
- Rui Tian
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for modulating a genome
- Patent number 12,157,898
- Issue date Dec 3, 2024
- FLAGSHIP PIONEERING INNOVATIONS VI, LLC
- Anne Helen Bothmer
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
DNA sequence modification-based gene drive
- Patent number 12,157,883
- Issue date Dec 3, 2024
- California Institute of Technology
- Bruce A Hay
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CRISPR gene therapy of fusion gene related cancers
- Patent number 12,157,905
- Issue date Dec 3, 2024
- Aarhus Universitet
- Christian Kanstrup Holm
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified CAS9 protein, and use thereof
- Patent number 12,152,259
- Issue date Nov 26, 2024
- The University of Tokyo
- Osamu Nureki
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Systems, methods, and compositions for correction of frameshift mut...
- Patent number 12,146,152
- Issue date Nov 19, 2024
- Massachusetts Institute of Technology
- Timothy Lu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Endothelial cell factors and methods thereof
- Patent number 12,146,165
- Issue date Nov 19, 2024
- THE CHILDREN'S MEDICAL CENTER CORPORATION
- Leonard I. Zon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Generation of induced pluripotent cells by CRISPR activation
- Patent number 12,146,166
- Issue date Nov 19, 2024
- The J. David Gladstone Institutes
- Peng Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Composition for editing a nucleic acid sequence and method using th...
- Patent number 12,139,716
- Issue date Nov 12, 2024
- Lung-Jr Lin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multiplexed genome editing
- Patent number 12,133,515
- Issue date Nov 5, 2024
- President and Fellows of Harvard College
- George M. Church
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of substituting pathogenic amino acids using programmable b...
- Patent number 12,133,884
- Issue date Nov 5, 2024
- Beam Therapeutics Inc.
- David Bryson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Targeted integration of nucleic acids
- Patent number 12,129,480
- Issue date Oct 29, 2024
- Genentech, Inc.
- Chi Kin Domingos Ng
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Haplotype-based treatment of RP1 associated retinal degenerations
- Patent number 12,129,496
- Issue date Oct 29, 2024
- Massachusetts Eye and Ear Infirmary
- Qin Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods and compositions for modulating a genome
- Patent number 12,123,034
- Issue date Oct 22, 2024
- FLAGSHIP PIONEERING INNOVATIONS VI, LLC
- Robert Charles Altshuler
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
- Patent number 12,123,015
- Issue date Oct 22, 2024
- The Regents of the University of California
- Jennifer A. Doudna
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Class II, type V CRISPR systems
- Patent number 12,123,014
- Issue date Oct 22, 2024
- METAGENOMI, INC.
- Brian Thomas
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleases and compositions, systems, and methods thereof
- Patent number 12,123,016
- Issue date Oct 22, 2024
- Profluent Bio Inc.
- Ali Madani
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Base editing of ANGPTL3 and methods of using same for treatment of...
- Patent number 12,115,230
- Issue date Oct 15, 2024
- Verve Therapeutics, Inc.
- Alexandra Chadwick
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Systems and methods of assisted reproduction and prevention of gene...
- Patent number 12,115,037
- Issue date Oct 15, 2024
- Sapphiros AI Bio LLC
- Robin Y. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Optimized protein linkers and methods of use
- Patent number 12,110,517
- Issue date Oct 8, 2024
- PAIRWISE PLANTS SERVICES, INC.
- Sharon Leigh Guffy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Homology directed repair compositions for the treatment of hemoglob...
- Patent number 12,110,499
- Issue date Oct 8, 2024
- Seattle Children's Hospital
- Andrew Scharenberg
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Universal donor stem cells and related methods
- Patent number 12,110,500
- Issue date Oct 8, 2024
- President and Fellows of Harvard College
- Torsten B. Meissner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
NANOS knock-out that ablates germline cells
- Patent number 12,102,069
- Issue date Oct 1, 2024
- Washington State University
- Jon Michael Oatley
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Methods for efficient delivery of therapeutic molecules in vitro an...
- Patent number 12,102,691
- Issue date Oct 1, 2024
- Massachusetts Eye and Ear Infirmary
- Zheng-Yi Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions and methods for differential Cas9 gene labeling and/or...
- Patent number 12,098,381
- Issue date Sep 24, 2024
- University of Massachusetts
- Thoru Pederson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lentiviral vector and method for delivering exogenous RNA by the le...
- Patent number 12,091,674
- Issue date Sep 17, 2024
- SHANGHAI BDGENE TECHNOLOGY CO., LTD.
- Yujia Cai
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Carboxylated nanodiamond-mediated CRISPR-CAS9 delivery system
- Patent number 12,091,677
- Issue date Sep 17, 2024
- Taipei Veterans General Hospital
- Shih-Hwa Chiou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Using programmable DNA binding proteins to enhance targeted genome...
- Patent number 12,084,675
- Issue date Sep 10, 2024
- Sigma-Aldrich Co. LLC
- Fuqiang Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
Methods and Compositions for RNA-Directed Target DNA Modification a...
- Publication number 20240417756
- Publication date Dec 19, 2024
- The Regents of the University of California
- Jennifer A. Doudna
- H01 - BASIC ELECTRIC ELEMENTS
Information Patent Application
PAPN MUTANT AND COMPOSITION FOR SITE-DIRECTED MODIFICATION OF PAPN...
- Publication number 20240417711
- Publication date Dec 19, 2024
- AGSINO GENSOURCES CO., LTD.
- Kui LI
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
METHODS AND COMPOSITIONS FOR EDITING A GENOME WITH PRIME EDITING AN...
- Publication number 20240417719
- Publication date Dec 19, 2024
- THE BROAD INSTITUTE, INC.
- David R. Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FUSION POLYPEPTIDES FOR GENETIC EDITING AND METHODS OF USE THEREOF
- Publication number 20240417755
- Publication date Dec 19, 2024
- VOR BIOPHARMA INC.
- Elizabeth Paik
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS AND COMPOSITIONS FOR MODULATING A GENOME
- Publication number 20240417757
- Publication date Dec 19, 2024
- Flagship Pioneering Innovations VI, LLC.
- Anne Helen BOTHMER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD FOR SITE-DIRECTED INTEGRATION OF TARGET GENE INTO SPECIFIC S...
- Publication number 20240415962
- Publication date Dec 19, 2024
- XI'AN YUFAN BIOTECHNOLOGIES CO., LTD.
- Fei LONG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Precise Excisions of Portions of Exons for Treatment of Duchenne Mu...
- Publication number 20240415984
- Publication date Dec 19, 2024
- VERTEX PHARMACEUTICALS INCORPORATED
- Tudor Fulga
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENDOTHELIAL CELL FACTORS AND METHODS THEREOF
- Publication number 20240417695
- Publication date Dec 19, 2024
- The Children's Medical Center Corporation
- Leonard I. ZON
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR IMPROVED GENOME EDITING WITH NME2CAS9...
- Publication number 20240417707
- Publication date Dec 19, 2024
- University of Massachusetts
- Erik Joseph Sontheimer
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS AND COMPOSITIONS FOR GENOME EDITING
- Publication number 20240409961
- Publication date Dec 12, 2024
- Salk Institute for Biological Studies
- Juan Carlos IZPISUA BELMONTE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CAR T CELLS GENERATED BY EFFECTOR PROTEINS AND METHODS RELATED THERETO
- Publication number 20240409893
- Publication date Dec 12, 2024
- MAMMOTH BIOSCIENCES, INC.
- Subhadra JAYARAMAN RUKMINI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GUIDE RNAS AND USES THEREOF
- Publication number 20240409923
- Publication date Dec 12, 2024
- Spotlight Therapeutics
- Benjamin G. Gowen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENDONUCLEASE SYSTEMS
- Publication number 20240409962
- Publication date Dec 12, 2024
- METAGENOMI, INC.
- Brian C. THOMAS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Use of Inhibitors to Increase Efficiency of Crispr/CAS Insertions
- Publication number 20240409963
- Publication date Dec 12, 2024
- AstraZeneca AB
- Marcello Maresca
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONVERSION-RESISTANT / CONDITION-RESISTANT TREGS AND CAR TREGS, MET...
- Publication number 20240408201
- Publication date Dec 12, 2024
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Mohsen Khosravi Maharlooei
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD OF MODULATING PCSK9 AND USES THEREOF
- Publication number 20240408236
- Publication date Dec 12, 2024
- Epigenic Therapeutics, Inc.
- Changyang ZHOU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSPOSON COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20240401085
- Publication date Dec 5, 2024
- Poseida Therapeutics, Inc.
- Joseph S. LUCAS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS
- Publication number 20240400684
- Publication date Dec 5, 2024
- THE REGENTS OF THE UNIVESITY OF CALIFORNIA
- Jacob Corn
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND...
- Publication number 20240401084
- Publication date Dec 5, 2024
- LifeEDIT Therapeutics, Inc.
- Alexandra Briner Crawley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Correction
- Publication number 20240401034
- Publication date Dec 5, 2024
- The Board of Trustees of the Leland Stanford Junior University
- Matthew H. Porteus
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-MEIOTIC ALLELE INTROGRESSION
- Publication number 20240397918
- Publication date Dec 5, 2024
- Recombinetics, Inc.
- Scott C. Fahrenkrug
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED CASX REPRESSOR SYSTEMS
- Publication number 20240392271
- Publication date Nov 28, 2024
- Scribe Therapeutics Inc.
- Jason FERNANDES
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...
- Publication number 20240390523
- Publication date Nov 28, 2024
- Verve Therapeutics, Inc.
- Alexandra Chadwick
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSPOSASE AND USES THEREOF
- Publication number 20240392262
- Publication date Nov 28, 2024
- Poseida Therapeutics, Inc.
- Dongyang ZHANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODY RESISTANT MODIFIED RECEPTORS TO ENHANCE CELL-BASED THERAPIES
- Publication number 20240390460
- Publication date Nov 28, 2024
- Regeneron Pharmaceuticals, Inc.
- Michael Moore
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DNA CONSTRUCTS FOR IMPROVED T CELL IMMUNOTHERAPY OF CANCER
- Publication number 20240392243
- Publication date Nov 28, 2024
- The Regents of the University of California
- Theodore Lee ROTH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Nucleotides Comprising CasPhi Modified for Nuclear Targeting
- Publication number 20240392322
- Publication date Nov 28, 2024
- Vanderbilt University
- Tonia S. Rex
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CRISPR-CAS13 SYSTEM AND USE THEREOF
- Publication number 20240392323
- Publication date Nov 28, 2024
- GUANGZHOU REFORGENE MEDICINE CO., LTD.
- Junbin Liang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR DELAYING CRISPR ACTION AND IMPROVING GENE DRIVE EFFECTI...
- Publication number 20240392287
- Publication date Nov 28, 2024
- The Regents of the University of California
- Valentino Matteo GANTZ
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
INHIBITOR OLIGONUCLEOTIDES AND METHODS OF USE THEREOF
- Publication number 20240384304
- Publication date Nov 21, 2024
- VOR BIOPHARMA INC.
- Dane Hazelbaker
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

in mammalian cells

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Engineered class 2 type V CRISPR systems

Non-human animals having a humanized signal-regulatory protein gene

Type II CRISPR/Cas9 genome editing system and the application thereof

Methods and compositions for modulating a genome

DNA sequence modification-based gene drive

CRISPR gene therapy of fusion gene related cancers

Modified CAS9 protein, and use thereof

Systems, methods, and compositions for correction of frameshift mut...

Endothelial cell factors and methods thereof

Generation of induced pluripotent cells by CRISPR activation

Composition for editing a nucleic acid sequence and method using th...

Multiplexed genome editing

Methods of substituting pathogenic amino acids using programmable b...

Targeted integration of nucleic acids

Haplotype-based treatment of RP1 associated retinal degenerations

Methods and compositions for modulating a genome

Methods and compositions for RNA-directed target DNA modification a...

Class II, type V CRISPR systems

Nucleases and compositions, systems, and methods thereof

Base editing of ANGPTL3 and methods of using same for treatment of...

Systems and methods of assisted reproduction and prevention of gene...

Optimized protein linkers and methods of use

Homology directed repair compositions for the treatment of hemoglob...

Universal donor stem cells and related methods

NANOS knock-out that ablates germline cells

Methods for efficient delivery of therapeutic molecules in vitro an...

Compositions and methods for differential Cas9 gene labeling and/or...

Lentiviral vector and method for delivering exogenous RNA by the le...

Carboxylated nanodiamond-mediated CRISPR-CAS9 delivery system

Using programmable DNA binding proteins to enhance targeted genome...

Patents Applicationslast 30 patents

Methods and Compositions for RNA-Directed Target DNA Modification a...

PAPN MUTANT AND COMPOSITION FOR SITE-DIRECTED MODIFICATION OF PAPN...

METHODS AND COMPOSITIONS FOR EDITING A GENOME WITH PRIME EDITING AN...

FUSION POLYPEPTIDES FOR GENETIC EDITING AND METHODS OF USE THEREOF

METHODS AND COMPOSITIONS FOR MODULATING A GENOME

METHOD FOR SITE-DIRECTED INTEGRATION OF TARGET GENE INTO SPECIFIC S...

Precise Excisions of Portions of Exons for Treatment of Duchenne Mu...

ENDOTHELIAL CELL FACTORS AND METHODS THEREOF

COMPOSITIONS AND METHODS FOR IMPROVED GENOME EDITING WITH NME2CAS9...

METHODS AND COMPOSITIONS FOR GENOME EDITING

CAR T CELLS GENERATED BY EFFECTOR PROTEINS AND METHODS RELATED THERETO

GUIDE RNAS AND USES THEREOF

ENDONUCLEASE SYSTEMS

Use of Inhibitors to Increase Efficiency of Crispr/CAS Insertions

CONVERSION-RESISTANT / CONDITION-RESISTANT TREGS AND CAR TREGS, MET...

METHOD OF MODULATING PCSK9 AND USES THEREOF

TRANSPOSON COMPOSITIONS AND METHODS OF USE THEREOF

ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS

RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND...

Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Correction

NON-MEIOTIC ALLELE INTROGRESSION

ENGINEERED CASX REPRESSOR SYSTEMS

BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...

TRANSPOSASE AND USES THEREOF

ANTIBODY RESISTANT MODIFIED RECEPTORS TO ENHANCE CELL-BASED THERAPIES

DNA CONSTRUCTS FOR IMPROVED T CELL IMMUNOTHERAPY OF CANCER

Nucleotides Comprising CasPhi Modified for Nuclear Targeting

CRISPR-CAS13 SYSTEM AND USE THEREOF

METHODS FOR DELAYING CRISPR ACTION AND IMPROVING GENE DRIVE EFFECTI...

INHIBITOR OLIGONUCLEOTIDES AND METHODS OF USE THEREOF